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Norbert Krug

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S Switalla; A Braun; Clemens Dasenbrock; Jan W Knebel; Norbert Krug; Detlef Ritter; K Sewald
Determination of genotoxicity by the Comet assay applied to murine precision-cut lung slices.
Ole Janssen; Norbert Krug; Bianca Lavae-Mokhtari; Frank Schaumann; Lutz Welker; Carla Winkler; Heike Biller; Olaf Holz; Jens M Hohlfeld
Low-dose endotoxin inhalation in healthy volunteers - a challenge model for early clinical drug development.
Philipp Badorrek; Melanie Dick; Lorenz Emmert; Hartmut Hecker; Jens M Hohlfeld; Wolfgang Koch; Robert Murdoch; Frank Schaumann; Norbert Krug
Pollen starch granules in bronchial inflammation.

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2013: S Switalla; A Braun; Clemens Dasenbrock; Jan W Knebel; Norbert Krug; Detlef Ritter; K Sewald
Determination of genotoxicity by the Comet assay applied to murine precision-cut lung slices.
Toxicology in vitro : an international journal published in association with BIBRA 2013;27(2):798-803.
2013: Ole Janssen; Norbert Krug; Bianca Lavae-Mokhtari; Frank Schaumann; Lutz Welker; Carla Winkler; Heike Biller; Olaf Holz; Jens M Hohlfeld
Low-dose endotoxin inhalation in healthy volunteers - a challenge model for early clinical drug development.
BMC pulmonary medicine 2013;13():19.
2012: Philipp Badorrek; Melanie Dick; Lorenz Emmert; Hartmut Hecker; Jens M Hohlfeld; Wolfgang Koch; Robert Murdoch; Frank Schaumann; Norbert Krug
Pollen starch granules in bronchial inflammation.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2012;109(3):208-214.e6.
2012: Carsten Schleh; Fabian Blank; Armin Braun; Veit J Erpenbeck; Peter Gehr; Norbert Krug; Hans D Lauenstein; Matthias Nassimi; Barbara M Rothen-Rutishauser; Jens Hohlfeld
Surfactant Protein D modulates allergen particle uptake and inflammatory response in a human epithelial airway model.
Respiratory research 2012;13():8.
2011: Heike Biller; Olaf Holz; Rudolf A Jörres; Wolfgang Koch; Norbert Krug; Meike Müller; Horst Windt; Jens M Hohlfeld
Breath profiles by electronic nose correlate with systemic markers but not ozone response.
Respiratory medicine 2011;105(9):1352-63.
2011: Philipp Badorrek; Melanie Dick; Hartmut Hecker; Frank Schaumann; Ana R Sousa; Robert Murdoch; Jens M Hohlfeld; Norbert Krug
Anti-allergic drug testing in an environmental challenge chamber is suitable both in and out of the relevant pollen season.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2011;106(4):336-41.
2011: Elena N Atochina-Vasserman; Carla Winkler; Helen Abramova; Frank Schaumann; Norbert Krug; Andrew J Gow; Michael F Beers; Jens Hohlfeld
Segmental allergen challenge alters multimeric structure and function of surfactant protein D in humans.
American journal of respiratory and critical care medicine 2011;183(7):856-64.
2011: H D Lauenstein; David Quarcoo; L Plappert; C Schleh; M Nassimi; C Pilzner; S Rochlitzer; P Brabet; T Welte; Heinz G Hoymann; Norbert Krug; M Müller; E A Lerner; Armin Braun; David A Groneberg
Pituitary adenylate cyclase-activating peptide receptor 1 mediates anti-inflammatory effects in allergic airway inflammation in mice.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2011;41(4):592-601.
2011: Jens Tank; Heike Biller; Karsten Heusser; Olaf Holz; André Diedrich; Theodor Framke; Armin Koch; Anika Grosshennig; Wolfgang Koch; Norbert Krug; Jens Jordan; Jens M Hohlfeld
Effect of acute ozone induced airway inflammation on human sympathetic nerve traffic: a randomized, placebo controlled, crossover study.
PloS one 2011;6(4):e18737.
2011: Carla Winkler; Elena N Atochina-Vasserman; Olaf Holz; Michael F Beers; Veit J Erpenbeck; Norbert Krug; Stefan Roepcke; Gereon Lauer; Martin Elmlinger; Jens Hohlfeld
Comprehensive characterisation of pulmonary and serum surfactant protein D in COPD.
Respiratory research 2011;12():29.
2010: Carla Winkler; Katja Hüper; Ann-Carina Wedekind; Sabine Rochlitzer; Christina Hartwig; Meike Müller; Armin Braun; Norbert Krug; Jens M Hohlfeld; Veit J Erpenbeck
Surfactant protein D modulates pulmonary clearance of pollen starch granules.
Experimental lung research 2010;36(9):522-30.
2010: Jens Hohlfeld; T Holland-Letz; Michael Larbig; M Lavae-Mokhtari; E Wierenga; M Kapsenberg; R van Ree; Norbert Krug; A Bufe
Diagnostic value of outcome measures following allergen exposure in an environmental challenge chamber compared with natural conditions.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2010;40(7):998-1006.
2010: S Switalla; Jan W Knebel; Detlef Ritter; Norbert Krug; Armin Braun; K Sewald
Effects of acute in vitro exposure of murine precision-cut lung slices to gaseous nitrogen dioxide and ozone in an air-liquid interface (ALI) culture.
Toxicology letters 2010;196(2):117-24.
2010: M Nassimi; C Schleh; H D Lauenstein; R Hussein; Heinz G Hoymann; Wolfgang Koch; Gerhard Pohlmann; Norbert Krug; K Sewald; Susanne Rittinghausen; Armin Braun; Christel C Müller-Goymann
A toxicological evaluation of inhaled solid lipid nanoparticles used as a potential drug delivery system for the lung.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2010;75(2):107-16.
2010: Carsten Schleh; Veit J Erpenbeck; Carla Winkler; Hans D Lauenstein; Matthias Nassimi; Armin Braun; Norbert Krug; Jens Hohlfeld
Allergen particle binding by human primary bronchial epithelial cells is modulated by surfactant protein D.
Respiratory research 2010;11():83.
2010: Barbara Fuchs; Saskia Knothe; Sabine Rochlitzer; Matthias Nassimi; Marina Pils; Hans-Dieter Lauenstein; Christina Nassenstein; Meike Müller; Thomas Ebensen; Anna-Maria Dittrich; Norbert Krug; Carlos A Guzman; Armin Braun
A Toll-like receptor 2/6 agonist reduces allergic airway inflammation in chronic respiratory sensitisation to Timothy grass pollen antigens.
International archives of allergy and immunology 2010;152(2):131-9.
2009: Matthias Nassimi; Carsten Schleh; Hans-Dieter Lauenstein; Riem Hussein; Katrin Lübbers; Gerhard Pohlmann; Simone Switalla; Katherina Sewald; Meike Müller; Norbert Krug; Christel C Müller-Goymann; Armin Braun
Low cytotoxicity of solid lipid nanoparticles in in vitro and ex vivo lung models.
Inhalation toxicology 2009;21 Suppl 1():104-9.
2009: Tibor Veres; Marina Shevchenko; Gabriela Krasteva; Emma Spies; Frauke Prenzler; Sabine Rochlitzer; Thomas Tschernig; Norbert Krug; Wolfgang Kummer; Armin Braun
Dendritic cell-nerve clusters are sites of T cell proliferation in allergic airway inflammation.
The American journal of pathology 2009;174(3):808-17.
2009: Veit J Erpenbeck; Norbert Krug; Jens M Hohlfeld
Therapeutic use of surfactant components in allergic asthma.
Naunyn-Schmiedeberg's archives of pharmacology 2009;379(3):217-24.
2009: Carsten Schleh; Christian Mühlfeld; Karin Pulskamp; Andreas Schmiedl; Matthias Nassimi; Hans D Lauenstein; Armin Braun; Norbert Krug; Veit J Erpenbeck; Jens M Hohlfeld
The effect of titanium dioxide nanoparticles on pulmonary surfactant function and ultrastructure.
Respiratory research 2009;10():90.
2009: Veit J Erpenbeck; Ina Fischer; Kathrin Wiese; Frank Schaumann; Andreas Schmiedl; Christina Nassenstein; Norbert Krug; Jens Hohlfeld
Therapeutic surfactants modulate the viability of eosinophils and induce inflammatory mediator release.
International archives of allergy and immunology 2009;149(4):333-42.
2009: Heinz-Gerd Hoymann; Lutz Wollin; Meike Muller; Regina Korolewitz; Norbert Krug; Armin Braun; Rolf Beume
Effects of the phosphodiesterase type 4 inhibitor roflumilast on early and late allergic response and airway hyperresponsiveness in Aspergillus-fumigatus-sensitized mice.
Pharmacology 2009;83(3):188-95.
2008: M Henjakovic; C Martin; Heinz G Hoymann; K Sewald; A R Ressmeyer; C Dassow; Gerhard Pohlmann; Norbert Krug; S Uhlig; Armin Braun
Ex vivo lung function measurements in precision-cut lung slices (PCLS) from chemical allergen-sensitized mice represent a suitable alternative to in vivo studies.
Toxicological sciences : an official journal of the Society of Toxicology 2008;106(2):444-53.
2008: Mathias Pletz; Ulrich Maus; Norbert Krug; Tobias Welte; Hartmut Lode
Pneumococcal vaccines: mechanism of action, impact on epidemiology and adaption of the species.
International journal of antimicrobial agents 2008;32(3):199-206.
2008: M Henjakovic; K Sewald; S Switalla; D Kaiser; M Müller; Tibor Veres; C Martin; S Uhlig; Norbert Krug; Armin Braun
Ex vivo testing of immune responses in precision-cut lung slices.
Toxicology and applied pharmacology 2008;231(1):68-76.
2008: Jens Hohlfeld; Kerstin Schoenfeld; Mehyar Lavae-Mokhtari; Frank Schaumann; Meike Mueller; Dirk Bredenbroeker; Norbert Krug; Robert Hermann
Roflumilast attenuates pulmonary inflammation upon segmental endotoxin challenge in healthy subjects: a randomized placebo-controlled trial.
Pulmonary pharmacology & therapeutics 2008;21(4):616-23.
2008: Frank Schaumann; Meike Müller; Armin Braun; Birgit Luettig; David Peden; Jens Hohlfeld; Norbert Krug
Endotoxin augments myeloid dendritic cell influx into the airways in patients with allergic asthma.
American journal of respiratory and critical care medicine 2008;177(12):1307-13.
2008: Norbert Krug; Klaus F Rabe
Animal models for human asthma: the perspective of a clinician.
Current drug targets 2008;9(6):438-42.
2007: Christina Nassenstein; Thomas Kammertoens; Tibor Veres; Wolfgang Uckert; Emma Spies; Barbara Fuchs; Norbert Krug; Armin Braun
Neuroimmune crosstalk in asthma: dual role of the neurotrophin receptor p75NTR.
The Journal of allergy and clinical immunology 2007;120(5):1089-96.
2007: Tibor Veres; Sabine Rochlitzer; Marina Shevchenko; Barbara Fuchs; Frauke Prenzler; Christina Nassenstein; Axel Fischer; Lutz Welker; Olaf Holz; Meike Müller; Norbert Krug; Armin Braun
Spatial interactions between dendritic cells and sensory nerves in allergic airway inflammation.
American journal of respiratory cell and molecular biology 2007;37(5):553-61.
2007: Alexander G Chuchalin; Alla N Tsoi; Kai Richter; Norbert Krug; Ronald Dahl; P B Luursema; Ray Cameron; Weibin Bao; Mark Higgins; Ralph Woessner; Andre van As
Safety and tolerability of indacaterol in asthma: a randomized, placebo-controlled 28-day study.
Respiratory medicine 2007;101(10):2065-75.
2007: Heinz Fehrenbach; Antonia Fehrenbach; Erik Dietzel; Thomas Tschernig; Norbert Krug; Veronika Grau; Jens Hohlfeld
Effects of keratinocyte growth factor on intra-alveolar surfactant fixed in situ: Quantitative ultrastructural and immunoelectron microscopic analysis.
Anatomical record (Hoboken, N.J. : 2007) 2007;290(8):974-80.
2007: Irina Kouznetsova; Caroline E Chwieralski; Ralf Bälder; Margitta Hinz; Armin Braun; Norbert Krug; Werner Hoffmann
Induced trefoil factor family 1 expression by trans-differentiating Clara cells in a murine asthma model.
American journal of respiratory cell and molecular biology 2007;36(3):286-95.
2006: Thomas Glaab; Jens Hohlfeld; Rudolf A Jörres; Norbert Krug; Tobias Welte
[Pathomechanisms in chronic obstructive pulmonary disease (COPD)].
Medizinische Klinik (Munich, Germany : 1983) 2006;101(12):951-6.
2006: Thomas Thum; Veit J Erpenbeck; Julia Moeller; Jens Hohlfeld; Norbert Krug; Jürgen Borlak
Expression of xenobiotic metabolizing enzymes in different lung compartments of smokers and nonsmokers.
Environmental health perspectives 2006;114(11):1655-61.
2006: Christina Nassenstein; David Dawbarn; Kenneth Pollock; Shelley J Allen; Veit J Erpenbeck; Emma Spies; Norbert Krug; Armin Braun
Pulmonary distribution, regulation, and functional role of Trk receptors in a murine model of asthma.
The Journal of allergy and clinical immunology 2006;118(3):597-605.
2006: Michael Larbig; Bernard Burtin; Laurent Martin; Holger Stamm; Birgit Luettig; Jens Hohlfeld; Norbert Krug
Facial thermography is a sensitive tool to determine antihistaminic activity: comparison of levocetirizine and fexofenadine.
British journal of clinical pharmacology 2006;62(2):158-64.
2006: Veit J Erpenbeck; M Ziegert; D Cavalet-Blanco; C Martin; Ralf Baelder; Thomas Glaab; Armin Braun; W Steinhilber; Birgit Luettig; S Uhlig; Heinz G Hoymann; Norbert Krug; Jens Hohlfeld
Surfactant protein D inhibits early airway response in Aspergillus fumigatus-sensitized mice.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2006;36(7):930-40.
2006: Veit J Erpenbeck; R Schmidt; A Günther; Norbert Krug; Jens Hohlfeld
Surfactant protein levels in bronchoalveolar lavage after segmental allergen challenge in patients with asthma.
Allergy 2006;61(5):598-604.
2006: Thomas Glaab; H Hecker; Michael Stephan; Ralf Baelder; Armin Braun; Regina Korolewitz; Norbert Krug; Heinz G Hoymann
Comparison of non-invasive measures of cholinergic and allergic airway responsiveness in rats.
Acta physiologica (Oxford, England) 2006;186(4):301-8.
2006: Norbert Krug
Usefulness of pollen chamber in the evaluation of clinical trials with allergen products.
Arbeiten aus dem Paul-Ehrlich-Institut (Bundesamt für Sera und Impfstoffe) zu Frankfurt a.M 2006;(95):167-70; discussion 170-1.
2006: KC Müller; Lutz Welker; K Paasch; B Feindt; Veit J Erpenbeck; Jens Hohlfeld; Norbert Krug; M Nakashima; Detlev Branscheid; Helgo Magnussen; Rudolf A Jörres; Olaf Holz
Lung fibroblasts from patients with emphysema show markers of senescence in vitro.
Respiratory research 2006;7():32.
2006: Veit J Erpenbeck; Andreas Hagenberg; Harald Krentel; Marc Discher; Armin Braun; Jens Hohlfeld; Norbert Krug
Regulation of GATA-3, c-maf and T-bet mRNA expression in bronchoalveolar lavage cells and bronchial biopsies after segmental allergen challenge.
International archives of allergy and immunology 2006;139(4):306-16.
2005: Veit J Erpenbeck; Rudolf A Jörres; Marc Discher; Harald Krentel; Dimitrios Tsikas; Birgit Luettig; Norbert Krug; Jens Hohlfeld
Local nitric oxide levels reflect the degree of allergic airway inflammation after segmental allergen challenge in asthmatics.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2005;13(2):125-33.
2005: Henning Weigt; Christina Nassenstein; Thomas Tschernig; Peter F Mühlradt; Norbert Krug; Armin Braun
Efficacy of macrophage-activating lipopeptide-2 combined with interferon-gamma in a murine asthma model.
American journal of respiratory and critical care medicine 2005;172(5):566-72.
2005: Thomas Voshaar; Joachim Heyder; D Köhler; Norbert Krug; D Nowak; Gerhard Scheuch; H Schulz; C Witt
[Effects of particulate air pollution on human health. Statement of the German Society of Pneumology on the discussion about fine particulate air pollution].
Pneumologie (Stuttgart, Germany) 2005;59(7):470-6.
2005: Veit J Erpenbeck; Delphine C Malherbe; Stefanie Sommer; Andreas Schmiedl; Wolfram Steinhilber; Andrew J Ghio; Norbert Krug; Jo Rae Wright; Jens Hohlfeld
Surfactant protein D increases phagocytosis and aggregation of pollen-allergen starch granules.
American journal of physiology. Lung cellular and molecular physiology 2005;288(4):L692-8.
2005: Norbert Krug; Jens Hohlfeld; Henning Geldmacher; Michael Larbig; R Heermann; N Lavallee; D T Nguyen; Ursula Petzold; Robert Hermann
Effect of loteprednol etabonate nasal spray suspension on seasonal allergic rhinitis assessed by allergen challenge in an environmental exposure unit.
Allergy 2005;60(3):354-9.
2005: Aysefa Doganci; Tatjana Eigenbrod; Norbert Krug; George T De Sanctis; Michael Hausding; Veit J Erpenbeck; El-Bdaoui Haddad; Hans-Anton Lehr; Edgar Schmitt; Tobias Bopp; Karl-Josef Kallen; Udo Herz; Steffen Schmitt; Cornelia Luft; Oliver Hecht; Jens Hohlfeld; Hiroaki Ito; Norihiro Nishimoto; Kazuyuki Yoshizaki; Tadamitsu Kishimoto; Stefan Rose-John; Harald Renz; Markus F Neurath; Peter R Galle; Susetta Finotto
The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo.
The Journal of clinical investigation 2005;115(2):313-25.
2005: Ralf Baelder; Barbara Fuchs; Wilfried Bautsch; Jörg Zwirner; Jörg Köhl; Heinz G Hoymann; Thomas Glaab; Veit J Erpenbeck; Norbert Krug; Armin Braun
Pharmacological targeting of anaphylatoxin receptors during the effector phase of allergic asthma suppresses airway hyperresponsiveness and airway inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(2):783-9.
2005: Thomas Glaab; Michaela Ziegert; Ralf Baelder; Regina Korolewitz; Armin Braun; Jens Hohlfeld; Wayne Mitzner; Norbert Krug; Heinz G Hoymann
Invasive versus noninvasive measurement of allergic and cholinergic airway responsiveness in mice.
Respiratory research 2005;6():139.
2004: Frank Schaumann; Paul J A Borm; Andreas Herbrich; Johannes Knoch; Mike Pitz; Roel P F Schins; Birgit Luettig; Jens Hohlfeld; Joachim Heinrich; Norbert Krug
Metal-rich ambient particles (particulate matter 2.5) cause airway inflammation in healthy subjects.
American journal of respiratory and critical care medicine 2004;170(8):898-903.
2004: Thomas Glaab; Wayne Mitzner; Armin Braun; Heinrich Ernst; Regina Korolewitz; Jens Hohlfeld; Norbert Krug; Heinz G Hoymann
Repetitive measurements of pulmonary mechanics to inhaled cholinergic challenge in spontaneously breathing mice.
Journal of applied physiology (Bethesda, Md. : 1985) 2004;97(3):1104-11.
2004: Henning Weigt; Peter F Muhlradt; Michael Larbig; Norbert Krug; Armin Braun
The Toll-like receptor-2/6 agonist macrophage-activating lipopeptide-2 cooperates with IFN-gamma to reverse the Th2 skew in an in vitro allergy model.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(10):6080-6.
2004: Jens Hohlfeld; Andreas Schmiedl; Veit J Erpenbeck; Per Venge; Norbert Krug
Eosinophil cationic protein alters pulmonary surfactant structure and function in asthma.
The Journal of allergy and clinical immunology 2004;113(3):496-502.
2004: Veit J Erpenbeck; Andreas Hagenberg; Yasmin Dulkys; Jörn Elsner; Ralf Bälder; Harald Krentel; Marc Discher; Armin Braun; Norbert Krug; Jens Hohlfeld
Natural porcine surfactant augments airway inflammation after allergen challenge in patients with asthma.
American journal of respiratory and critical care medicine 2004;169(5):578-86.
2004: Jens Hohlfeld; Heinz G Hoymann; Thomas Tschernig; Antonia Fehrenbach; Norbert Krug; Heinz Fehrenbach
Keratinocyte growth factor transiently alters pulmonary function in rats.
Journal of applied physiology (Bethesda, Md. : 1985) 2004;96(2):704-10.
2004: Andreas Schmiedl; Norbert Krug; Jens Hohlfeld
Influence of plasma and inflammatory proteins on the ultrastructure of exogenous surfactant.
Journal of electron microscopy 2004;53(4):407-16.
2003: Norbert Krug; Jens Hohlfeld; Michael Larbig; A Buckendahl; P Badorrek; Henning Geldmacher; Wolfgang Behnke; W Dunkhorst; H Windt; B Loedding; Birgit Luettig; Wolfgang Koch
Validation of an environmental exposure unit for controlled human inhalation studies with grass pollen in patients with seasonal allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(12):1667-74.
2003: Thomas Glaab; Heinz G Hoymann; M Hecht; Regina Korolewitz; Thomas Tschernig; Jens Hohlfeld; Norbert Krug; Armin Braun
Effect of anti-nerve growth factor on early and late airway responses in allergic rats.
Allergy 2003;58(9):900-4.
2003: Christina Nassenstein; Armin Braun; Veit J Erpenbeck; Marek Lommatzsch; Stephanie Schmidt; Norbert Krug; Werner Luttmann; Harald Renz; J Christian Virchow
The neurotrophins nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 are survival and activation factors for eosinophils in patients with allergic bronchial asthma.
The Journal of experimental medicine 2003;198(3):455-67.
2003: Veit J Erpenbeck; Jens Hohlfeld; Brunhild Volkmann; Andreas Hagenberg; Henning Geldmacher; Armin Braun; Norbert Krug
Segmental allergen challenge in patients with atopic asthma leads to increased IL-9 expression in bronchoalveolar lavage fluid lymphocytes.
The Journal of allergy and clinical immunology 2003;111(6):1319-27.
2003: Antonia Fehrenbach; Christoph Bube; Jens Hohlfeld; Paul Stevens; Thomas Tschernig; Heinz G Hoymann; Norbert Krug; Heinz Fehrenbach
Surfactant homeostasis is maintained in vivo during keratinocyte growth factor-induced rat lung type II cell hyperplasia.
American journal of respiratory and critical care medicine 2003;167(9):1264-70.
2003: Veit J Erpenbeck; Jens Hohlfeld; Marc Discher; Harald Krentel; Andreas Hagenberg; Armin Braun; Norbert Krug
Increased expression of interleukin-9 messenger RNA after segmental allergen challenge in allergic asthmatics.
Chest 2003;123(3 Suppl):370S.
2003: Veit J Erpenbeck; Jens Hohlfeld; Marc Discher; Harald Krentel; Andreas Hagenberg; Armin Braun; Norbert Krug
Increased messenger RNA expression of c-maf and GATA-3 after segmental allergen challenge in allergic asthmatics.
Chest 2003;123(3 Suppl):370S-1S.
2003: Veit J Erpenbeck; Jens Hohlfeld; J Petschallies; Elisabeth Eklund; C G B Peterson; Helmut Fabel; Norbert Krug
Local release of eosinophil peroxidase following segmental allergen provocation in asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(3):331-6.
2003: Henning Weigt; Peter F Mühlradt; Andreas Emmendörffer; Norbert Krug; Armin Braun
Synthetic mycoplasma-derived lipopeptide MALP-2 induces maturation and function of dendritic cells.
Immunobiology 2003;207(3):223-33.
2003: Andreas Schmiedl; Heinz G Hoymann; Matthias Ochs; A Menke; Antonia Fehrenbach; Norbert Krug; Thomas Tschernig; Jens Hohlfeld
Increase of inactive intra-alveolar surfactant subtypes in lungs of asthmatic Brown Norway rats.
Virchows Archiv : an international journal of pathology 2003;442(1):56-65.
2002: Thomas Glaab; Heinz G Hoymann; Jens Hohlfeld; Regina Korolewitz; Matthias Hecht; Yves Alarie; Thomas Tschernig; Armin Braun; Norbert Krug; Helmut Fabel
Noninvasive measurement of midexpiratory flow indicates bronchoconstriction in allergic rats.
Journal of applied physiology (Bethesda, Md. : 1985) 2002;93(4):1208-14.
2002: Jens Hohlfeld; Veit J Erpenbeck; Norbert Krug
Surfactant proteins SP-A and SP-D as modulators of the allergic inflammation in asthma.
Pathobiology : journal of immunopathology, molecular and cellular biology 2002;70(5):287-92.
2001: Norbert Krug; Thomas Tschernig; Veit J Erpenbeck; Jens Hohlfeld; J Köhl
Complement factors C3a and C5a are increased in bronchoalveolar lavage fluid after segmental allergen provocation in subjects with asthma.
American journal of respiratory and critical care medicine 2001;164(10 Pt 1):1841-3.
2001: C Lehmann; A Wilkening; D Leiber; A Markus; Norbert Krug; Reinhard Pabst; Thomas Tschernig
Lymphocytes in the bronchoalveolar space reenter the lung tissue by means of the alveolar epithelium, migrate to regional lymph nodes, and subsequently rejoin the systemic immune system.
The Anatomical record 2001;264(3):229-36.
2001: Norbert Krug; Veit J Erpenbeck; K Balke; J Petschallies; Thomas Tschernig; Jens Hohlfeld; Helmut Fabel
Cytokine profile of bronchoalveolar lavage-derived CD4(+), CD8(+), and gammadelta T cells in people with asthma after segmental allergen challenge.
American journal of respiratory cell and molecular biology 2001;25(1):125-31.
2000: Anke Lührmann; Rainer V Haberberger; Christiane Mörike; Gustav Steinhoff; Norbert Krug; Reinhard Pabst; Thomas Tschernig
[Recruitment of immunocompetent cells in a transplanted lung is not impaired despite incompletel reinnervation].
Pneumologie (Stuttgart, Germany) 2000;54(12):564-8.
2000: Norbert Krug; W W Cruikshank; Thomas Tschernig; Veit J Erpenbeck; K Balke; Jens Hohlfeld; David M Center; Helmut Fabel
Interleukin 16 and T-cell chemoattractant activity in bronchoalveolar lavage 24 hours after allergen challenge in asthma.
American journal of respiratory and critical care medicine 2000;162(1):105-11.
2000: G Enhorning; Jens Hohlfeld; Norbert Krug; G Lema; Robert C Welliver
Surfactant function affected by airway inflammation and cooling: possible impact on exercise-induced asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2000;15(3):532-8.
2000: M Schuster; Thomas Tschernig; Norbert Krug; R Pabst
Lymphocytes migrate from the blood into the bronchoalveolar lavage and lung parenchyma in the asthma model of the brown Norway rat.
American journal of respiratory and critical care medicine 2000;161(2 Pt 1):558-66.
2000: Emma Heeley; Jens Hohlfeld; Norbert Krug; Anthony D Postle
Phospholipid molecular species of bronchoalveolar lavage fluid after local allergen challenge in asthma.
American journal of physiology. Lung cellular and molecular physiology 2000;278(2):L305-11.
1999: Norbert Krug; U Napp; I Enander; Elisabeth Eklund; C H Rieger; Uwe Schauer
Intracellular expression and serum levels of eosinophil peroxidase (EPO) and eosinophil cationic protein in asthmatic children.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1999;29(11):1507-15.
1999: Jens Hohlfeld; K Ahlf; G Enhorning; K Balke; Veit J Erpenbeck; J Petschallies; Heinz G Hoymann; Helmut Fabel; Norbert Krug
Dysfunction of pulmonary surfactant in asthmatics after segmental allergen challenge.
American journal of respiratory and critical care medicine 1999;159(6):1803-9.
1999: Jens Hohlfeld; Martin Strüber; K Ahlf; Marius M Hoeper; Sandra Fraund; Norbert Krug; Gregor Warnecke; Wolfgang Harringer; Axel Haverich; Helmut Fabel
Exogenous surfactant improves survival and surfactant function in ischaemia-reperfusion injury in minipigs.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;13(5):1037-43.
1999: Norbert Krug; Thomas Tschernig; K Balke; Veit J Erpenbeck; L Meyer; U Bode; Jens Hohlfeld; Reinhard Pabst; Helmut Fabel
Enhanced expression of fas ligand (CD95L) on T cells after segmental allergen provocation in asthma.
The Journal of allergy and clinical immunology 1999;103(4):649-55.
1998: Norbert Krug; Thomas Jung; U Napp; K Wagner; G Schultze-Werninghaus; CH Heusser; Christian H L Rieger; Uwe Schauer; Helmut Fabel
Frequencies of T cells expressing interleukin-4 and interleukin-5 in atopic asthmatic children. Comparison with atopic asthmatic adults.
American journal of respiratory and critical care medicine 1998;158(3):754-9.
1998: Jens Hohlfeld; E Tiryaki; Hinrich Hamm; Heinz G Hoymann; Norbert Krug; Axel Haverich; Helmut Fabel
Pulmonary surfactant activity is impaired in lung transplant recipients.
American journal of respiratory and critical care medicine 1998;158(3):706-12.
1998: Annette Klemm; Thomas Tschernig; Norbert Krug; Reinhard Pabst
Lymphocyte subsets in distinct lung compartments show a different ability to produce interferon-gamma (IFN-gamma) during a pulmonary immune response.
Clinical and experimental immunology 1998;113(2):252-7.
1998: E Spiekerkoetter; Norbert Krug; Marius M Hoeper; Karsten Wiebe; M Hamm; Wolfgang Harringer; Axel Haverich; Helmut Fabel
Prevalence of malignancies after lung transplantation.
Transplantation proceedings 1998;30(4):1523-4.
1998: Karsten Wiebe; Wolfgang Harringer; Ulrich F W Franke; Martin Strüber; Norbert Krug; F Korff; Thorsten Wahlers; Jochen Cremer; Axel Haverich
FK506 rescue therapy in lung transplantation.
Transplantation proceedings 1998;30(4):1508-9.
1998: Anthony J Frew; Mary P Carroll; C Gratziou; Norbert Krug
Endobronchial allergen challenge.
The European respiratory journal. Supplement 1998;26():33S-35S.
1998: Norbert Krug; Thomas Tschernig; S Holgate; Reinhard Pabst
How do lymphocytes get into the asthmatic airways? Lymphocyte traffic into and within the lung in asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1998;28(1):10-8.
1997: J P Lührs; Norbert Krug; T H Schürmeyer
[Swollen parotid gland and lower leg erythema. Presentation of differential diagnosis and therapy based on a case report].
Fortschritte der Medizin 1997;115(25):39-42.
1997: Norbert Krug; Uwe Schauer; T O Wagner
[Cell biology of bronchial asthma: interesting new methods. Intracellular determination of cytokines in T-cells and basic proteins in eosinophilic granulocytes using flow cytometry].
Pneumologie (Stuttgart, Germany) 1997;51(4):381-5.
1997: Norbert Krug; Anthony J Frew
The Th2 cell in asthma: initial expectations yet to be realised.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1997;27(2):142-50.
1996: Uwe Schauer; Thomas Jung; Norbert Krug; A Frew
Measurement of intracellular cytokines.
Immunology today 1996;17(7):305-6.
1996: Norbert Krug; A M Thurau; P Lackie; JE Baier; G Schultze-Werninghaus; Christian H L Rieger; Uwe Schauer
A flow cytometric method for the detection of intracellular basic proteins in unseparated peripheral blood and bone marrow eosinophils.
Journal of immunological methods 1996;190(2):245-54.
1996: Norbert Krug; LM Teran; AE Redington; C Gratziou; stephen montefort; Riccardo Polosa; H Brewster; Peter H Howarth; Stephen T Holgate; Anthony J Frew; Mary P Carroll
Safety aspects of local endobronchial allergen challenge in asthmatic patients.
American journal of respiratory and critical care medicine 1996;153(4 Pt 1):1391-7.
1996: Norbert Krug; Jacqueline Madden; AE Redington; P Lackie; Ratko Djukanovic; Uwe Schauer; Stephen T Holgate; Anthony J Frew; Peter H Howarth
T-cell cytokine profile evaluated at the single cell level in BAL and blood in allergic asthma.
American journal of respiratory cell and molecular biology 1996;14(4):319-26.
1996: T O F Wagner; Norbert Krug; W H Hoffmeyer; Helmut Fabel
[Guidelines of the American Thoracic Society/American Lung Association for education in pneumology and in pneumology and intensive care medicine. Accreditation Council for Graduate Medical Education (ACGME)].
Pneumologie (Stuttgart, Germany) 1996;50(3):231-6.
1996: A M Thurau; U Schylz; V Wolf; Norbert Krug; U Schauer
Identification of eosinophils by flow cytometry.
Cytometry 1996;23(2):150-8.
1995: H Foth; W P Geng; Norbert Krug; F Vetterlein
Pulmonary uptake of bupivacaine in isolated perfused rat lung.
Naunyn-Schmiedeberg's archives of pharmacology 1995;351(1):99-106.
1993: Norbert Krug; Uwe Schauer; T O F Wagner; Helmut Fabel
[Is asthma a disease of the T-helper lymphocytes (TH2 Cells)? The significance of activated T-cells and eosinophils in chronic inflammatory reaction in bronchial asthma].
Medizinische Klinik (Munich, Germany : 1983) 1993;88(6):377-80.
1993: Norbert Krug; I Otterbach; L Wilkens; E Kupsch; Helmut Fabel
[Isolated late pulmonary metastasis of adenoid cystic carcinoma of the parotid gland].
Pneumologie (Stuttgart, Germany) 1993;47(5):357-60.