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Vladimir Krutovskikh

Research Profile

Chemicals & Drugs

Anatomy

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Genes, Tumor Suppressor

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Vladimir A Krutovskikh; Zdenko Herceg
Oncogenic microRNAs (OncomiRs) as a new class of cancer biomarkers.
Maria Lúcia Zaidan Dagli; Hiroshi Yamasaki; Vladimir A Krutovskikh; Yasufumi Omori
Delayed liver regeneration and increased susceptibility to chemical hepatocarcinogenesis in transgenic mice expressing a dominant-negative mutant of connexin32 only in the liver.
Brad L Upham; Junji Suzuki; Gang Chen; Yurong Wang; Laura R McCabe; Chia-Cheng Chang; Vladimir A Krutovskikh; Hiroshi Yamasaki; James E Trosko
Reduced gap junctional intercellular communication and altered biological effects in mouse osteoblast and rat liver oval cell lines transfected with dominant-negative connexin 43.

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All Publications

2010: Vladimir A Krutovskikh; Zdenko Herceg
Oncogenic microRNAs (OncomiRs) as a new class of cancer biomarkers.
BioEssays : news and reviews in molecular, cellular and developmental biology 2010;32(10):894-904.
2004: Maria Lúcia Zaidan Dagli; Hiroshi Yamasaki; Vladimir A Krutovskikh; Yasufumi Omori
Delayed liver regeneration and increased susceptibility to chemical hepatocarcinogenesis in transgenic mice expressing a dominant-negative mutant of connexin32 only in the liver.
Carcinogenesis 2004;25(4):483-92.
2003: Brad L Upham; Junji Suzuki; Gang Chen; Yurong Wang; Laura R McCabe; Chia-Cheng Chang; Vladimir A Krutovskikh; Hiroshi Yamasaki; James E Trosko
Reduced gap junctional intercellular communication and altered biological effects in mouse osteoblast and rat liver oval cell lines transfected with dominant-negative connexin 43.
Molecular carcinogenesis 2003;37(4):192-201.
2003: Gideon Berke; Vladimir A Krutovskikh; Hiroshi Yamasaki
Connexin 37 gene is not mutated in lung carcinomas 3LL and CMT.
Cancer letters 2003;195(1):67-72.
2003: N A Iaitskiĭ; Michael V Dubina; S V Vasil'ev; D E Popov; Vladimir A Krutovskikh
[The scientific and clinical value of molecular genetic changes in the intercellular gap junctions observed in colon cancer].
Vestnik Rossiĭskoĭ akademii meditsinskikh nauk / Rossiĭskaia akademiia meditsinskikh nauk 2003;(10):24-9.
2002: Vladimir A Krutovskikh
Implication of direct host-tumor intercellular interactions in non-immune host resistance to neoplastic growth.
Seminars in cancer biology 2002;12(4):267-76.
2002: Michael V Dubina; Nikolay A Iatckii; Dimitrii E Popov; Sergei V Vasil'ev; Vladimir A Krutovskikh
Connexin 43, but not connexin 32, is mutated at advanced stages of human sporadic colon cancer.
Oncogene 2002;21(32):4992-6.
2002: Vladimir A Krutovskikh; Colette Piccoli; Hiroshi Yamasaki; Horashi Yamasaki
Gap junction intercellular communication propagates cell death in cancerous cells.
Oncogene 2002;21(13):1989-99.
2000: Vladimir A Krutovskikh; Horashi Yamasaki
Connexin gene mutations in human genetic diseases.
Mutation research 2000;462(2-3):197-207.
2000: T Saito; Vladimir A Krutovskikh; M J Marion; KG Ishak; Patrick Williams; Horashi Yamasaki
Human hemangiosarcomas have a common polymorphism but no mutations in the connexin37 gene.
International journal of cancer. Journal international du cancer 2000;86(1):67-70.
2000: Vladimir A Krutovskikh; S M Troyanovsky; Colette Piccoli; H Tsuda; M Asamoto; Horashi Yamasaki
Differential effect of subcellular localization of communication impairing gap junction protein connexin43 on tumor cell growth in vivo.
Oncogene 2000;19(4):505-13.
1999: Horashi Yamasaki; Vladimir A Krutovskikh; Marc Mesnil; T Tanaka; Maria-Lucia Zaidan-Dagli; Yasufumi Omori
Role of connexin (gap junction) genes in cell growth control and carcinogenesis.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1999;322(2-3):151-9.
1999: Horashi Yamasaki; Yasufumi Omori; Maria-Lucia Zaidan-Dagli; Nikolai Mironov; Marc Mesnil; Vladimir A Krutovskikh
Genetic and epigenetic changes of intercellular communication genes during multistage carcinogenesis.
Cancer detection and prevention 1999;23(4):273-9.
1999: Horashi Yamasaki; Yasufumi Omori; Vladimir A Krutovskikh; W Zhu; Nikolai Mironov; K Yamakage; Marc Mesnil
Connexins in tumour suppression and cancer therapy.
Novartis Foundation symposium 1999;219():241-54; discussion 254-60.
1998: Vladimir A Krutovskikh; H Yamasaki; H Tsuda; M Asamoto
Inhibition of intrinsic gap-junction intercellular communication and enhancement of tumorigenicity of the rat bladder carcinoma cell line BC31 by a dominant-negative connexin 43 mutant.
Molecular carcinogenesis 1998;23(4):254-61.
1998: Makoto Asamoto; T Toriyama-Baba; Vladimir A Krutovskikh; S M Cohen; Hiroyuki Tsuda
Enhanced tumorigenicity of rat bladder squamous cell carcinoma cells after abrogation of gap junctional intercellular communication.
Japanese journal of cancer research : Gann 1998;89(5):481-6.
1997: Vladimir A Krutovskikh; Makoto Asamoto; Nobuo Takasuka; Michiaki Murakoshi; Hoyoku Nishino; Hiroyuki Tsuda
Differential dose-dependent effects of alpha-, beta-carotenes and lycopene on gap-junctional intercellular communication in rat liver in vivo.
Japanese journal of cancer research : Gann 1997;88(12):1121-4.
1997: Vladimir A Krutovskikh; Horashi Yamasaki
The role of gap junctional intercellular communication (GJIC) disorders in experimental and human carcinogenesis.
Histology and histopathology 1997;12(3):761-8.
1997: Kazunori Sekine; E Watanabe; J Nakamura; Nobuo Takasuka; Dae Joong Kim; Makoto Asamoto; Vladimir A Krutovskikh; H Baba-Toriyama; T Ota; Malcolm Moore; M Masuda; H Sugimoto; Hoyoku Nishino; T Kakizoe; Hiroyuki Tsuda
Inhibition of azoxymethane-initiated colon tumor by bovine lactoferrin administration in F344 rats.
Japanese journal of cancer research : Gann 1997;88(6):523-6.
1997: T Hori; Makoto Asamoto; Vladimir A Krutovskikh; Y Iwahori; M Maeda; Hiroyasu Toriyama-Baba; Nobuo Takasuka; Hiroyuki Tsuda
Triazine derivatives inhibit rat hepatocarcinogenesis but do not enhance gap junctional intercellular communication.
Japanese journal of cancer research : Gann 1997;88(1):12-7.
1996: Hiroyuki Tsuda; Makoto Asamoto; Y Iwahori; T Hori; T Ota; H Baba-Toriyama; N Uehara; Dae Joong Kim; Vladimir A Krutovskikh; Nobuo Takasuka; Takayuki Tsuchiya; M Mutai; M Tatematsu; H Yamasaki
Decreased connexin32 and a characteristic enzyme phenotype in clofibrate-induced preneoplastic lesions not shared with spontaneously occurring lesions in the rat liver.
Carcinogenesis 1996;17(11):2441-8.
1996: Yasufumi Omori; Vladimir A Krutovskikh; Nikolai Mironov; H Tsuda; Horashi Yamasaki
Cx32 gene mutation in a chemically induced rat liver tumour.
Carcinogenesis 1996;17(9):2077-80.
1996: Vladimir A Krutovskikh; Nikolai Mironov; Horashi Yamasaki
Human connexin 37 is polymorphic but not mutated in tumours.
Carcinogenesis 1996;17(8):1761-3.
1996: Horashi Yamasaki; Vladimir A Krutovskikh; Marc Mesnil; Yasufumi Omori
Connexin genes and cell growth control.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1996;18():105-14.
1995: Marc Mesnil; Vladimir A Krutovskikh; Yasufumi Omori; Horashi Yamasaki
Role of blocked gap junctional intercellular communication in non-genotoxic carcinogenesis.
Toxicology letters 1995;82-83():701-6.
1995: Horashi Yamasaki; Marc Mesnil; Yasufumi Omori; Nikolai Mironov; Vladimir A Krutovskikh
Intercellular communication and carcinogenesis.
Mutation research 1995;333(1-2):181-8.
1995: Vladimir A Krutovskikh; Marc Mesnil; Giovanna Mazzoleni; Horashi Yamasaki
Inhibition of rat liver gap junction intercellular communication by tumor-promoting agents in vivo. Association with aberrant localization of connexin proteins.
Laboratory investigation; a journal of technical methods and pathology 1995;72(5):571-7.
1995: Marc Mesnil; Vladimir A Krutovskikh; Colette Piccoli; C Elfgang; Otto Traub; Klaus Willecke; Horashi Yamasaki
Negative growth control of HeLa cells by connexin genes: connexin species specificity.
Cancer research 1995;55(3):629-39.
1994: Y Bager; Kerstin Kenne; Vladimir A Krutovskikh; Marc Mesnil; Otto Traub; Lars Wärngård
Alteration in expression of gap junction proteins in rat liver after treatment with the tumour promoter 3,4,5,3',4'-pentachlorobiphenyl.
Carcinogenesis 1994;15(11):2439-43.
1994: Vladimir A Krutovskikh; Giovanna Mazzoleni; Nikolai Mironov; Yasufumi Omori; A M Aguelon; Marc Mesnil; F Berger; C Partensky; Horashi Yamasaki
Altered homologous and heterologous gap-junctional intercellular communication in primary human liver tumors associated with aberrant protein localization but not gene mutation of connexin 32.
International journal of cancer. Journal international du cancer 1994;56(1):87-94.
1994: Vladimir A Krutovskikh; V S Turusov
Tumours of the intestines.
IARC scientific publications 1994;(111):195-221.
1993: Horashi Yamasaki; Vladimir A Krutovskikh; Marc Mesnil; amedeo columbano; H Tsuda; N Ito
Gap junctional intercellular communication and cell proliferation during rat liver carcinogenesis.
Environmental health perspectives 1993;101 Suppl 5():191-7.
1991: Vladimir A Krutovskikh; Masahito Oyamada; Horashi Yamasaki
Sequential changes of gap-junctional intercellular communications during multistage rat liver carcinogenesis: direct measurement of communication in vivo.
Carcinogenesis 1991;12(9):1701-6.
1990: Masahito Oyamada; Vladimir A Krutovskikh; Marc Mesnil; C Partensky; F Berger; Horashi Yamasaki
Aberrant expression of gap junction gene in primary human hepatocellular carcinomas: increased expression of cardiac-type gap junction gene connexin 43.
Molecular carcinogenesis 1990;3(5):273-8.