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Hanna Ksiezak-Reding

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Ismael Santa-Maria; Jun Wang; Alice Chen; Carmen Diaz-Ruiz; Lap Ho; Hanna Ksiezak-Reding; Giulio Maria Pasinetti
GSPE interferes with tau aggregation in vivo: implication for treating tauopathy.
Hanna Ksiezak-Reding; Carmen Diaz-Ruiz; Lap Ho; Ismael Santa-Maria; Jun Wang; Giulio Maria Pasinetti
Ultrastructural alterations of Alzheimer's disease paired helical filaments by grape seed-derived polyphenols.
Annette Tennstaedt; Anca Laura Tirniceriu; Linda Truebestein; Alfonso Baldi; Roland Brandt; Anke Brockmann; Tim Clausen; Leif Dehmelt; Rupert Egensperger; Patrick Hauske; Robert Huber; Inga Irle; Markus Kaiser; Hanna Ksiezak-Reding; Christof M Niemeyer; Simon Pöpsel; Barbara Sacca; Nina Schmidt; Michael Ehrmann
Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregates.

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2012: Ismael Santa-Maria; Jun Wang; Alice Chen; Carmen Diaz-Ruiz; Lap Ho; Hanna Ksiezak-Reding; Giulio Maria Pasinetti
GSPE interferes with tau aggregation in vivo: implication for treating tauopathy.
Neurobiology of aging 2012;33(9):2072-81.
2012: Hanna Ksiezak-Reding; Carmen Diaz-Ruiz; Lap Ho; Ismael Santa-Maria; Jun Wang; Giulio Maria Pasinetti
Ultrastructural alterations of Alzheimer's disease paired helical filaments by grape seed-derived polyphenols.
Neurobiology of aging 2012;33(7):1427-39.
2012: Annette Tennstaedt; Anca Laura Tirniceriu; Linda Truebestein; Alfonso Baldi; Roland Brandt; Anke Brockmann; Tim Clausen; Leif Dehmelt; Rupert Egensperger; Patrick Hauske; Robert Huber; Inga Irle; Markus Kaiser; Hanna Ksiezak-Reding; Christof M Niemeyer; Simon Pöpsel; Barbara Sacca; Nina Schmidt; Michael Ehrmann
Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregates.
The Journal of biological chemistry 2012;287(25):20931-41.
2012: Ismael Santa-Maria; Merina Varghese; Jun Wang; Anastasiya Dzhun; Hanna Ksiezak-Reding; Giulio M Pasinetti
Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes.
The Journal of biological chemistry 2012;287(24):20522-33.
2010: Giulio Maria Pasinetti; Hanna Ksiezak-Reding; Ismael Santa-Maria; Jun Wang; Lap Ho
Development of a grape seed polyphenolic extract with anti-oligomeric activity as a novel treatment in progressive supranuclear palsy and other tauopathies.
Journal of neurochemistry 2010;114(6):1557-68.
2010: Jun Wang; Ismael Santa-Maria; Lap Ho; Hanna Ksiezak-Reding; Kenjiro Ono; David B Teplow; Giulio Maria Pasinetti
Grape derived polyphenols attenuate tau neuropathology in a mouse model of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2010;22(2):653-61.
2009: C Díaz-Ruiz; Jun Wang; Hanna Ksiezak-Reding; Lap Ho; Xianjuan Qian; Nelson Humala; S Thomas; P Martínez-Martín; Giulio Maria Pasinetti
Role of Hypertension in Aggravating Abeta Neuropathology of AD Type and Tau-Mediated Motor Impairment.
Cardiovascular psychiatry and neurology 2009;2009():107286.
2007: Wanda Gordon-Krajcer; E Kozniewska; Jerzy W Lazarewicz; Hanna Ksiezak-Reding
Differential changes in phosphorylation of tau at PHF-1 and 12E8 epitopes during brain ischemia and reperfusion in gerbils.
Neurochemical research 2007;32(4-5):729-37.
2007: Giulio Maria Pasinetti; Rudy Zhao; Weiping Qin; Lap Ho; Yemul Shrishailam; Donal MacGrogan; Wendy Ressmann; Nelson Humala; Xunxian Liu; Carmen Romero; Breton Stetka; Linghong Chen; Hanna Ksiezak-Reding; Jun Wang
Caloric intake and Alzheimer's disease. Experimental approaches and therapeutic implications.
Interdisciplinary topics in gerontology 2007;35():159-75.
2006: Makio Takahashi; Hirotake Uchikado; Domenico Caprotti; Karen M Weidenheim; dennis dickson; Hanna Ksiezak-Reding; Giulio Maria Pasinetti
Identification of G-protein coupled receptor kinase 2 in paired helical filaments and neurofibrillary tangles.
Journal of neuropathology and experimental neurology 2006;65(12):1157-69.
2006: Rudy Zhao; Hanna Ksiezak-Reding; Silvana Riggio; Vahram Haroutunian; Giulio Maria Pasinetti
Insulin receptor deficits in schizophrenia and in cellular and animal models of insulin receptor dysfunction.
Schizophrenia research 2006;84(1):1-14.
2006: Weiping Qin; Y Peng; Hanna Ksiezak-Reding; Lap Ho; Breton Stetka; E Lovati; Giulio Maria Pasinetti
Inhibition of cyclooxygenase as potential novel therapeutic strategy in N141I presenilin-2 familial Alzheimer's disease.
Molecular psychiatry 2006;11(2):172-81.
2005: Hanna Ksiezak-Reding; Joseph S Wall
Characterization of paired helical filaments by scanning transmission electron microscopy.
Microscopy research and technique 2005;67(3-4):126-40.
2005: Rudy Zhao; Hanna Ksiezak-Reding; Jun Wang; Giulio Maria Pasinetti
Expression of tau reduces secretion of Abeta without altering the amyloid precursor protein content in CHOsw cells.
FEBS letters 2005;579(10):2119-24.
2004: Gloria Lee; Ramasamy Thangavel; Vandana Sharma; Joel M Litersky; Kiran Bhaskar; Sandy M Fang; Lana H Do; Athena Andreadis; Gary W Van Hoesen; Hanna Ksiezak-Reding
Phosphorylation of tau by fyn: implications for Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(9):2304-12.
2004: H Kyoung Pyo; E Lovati; Giulio Maria Pasinetti; Hanna Ksiezak-Reding
Phosphorylation of tau at THR212 and SER214 in human neuronal and glial cultures: the role of AKT.
Neuroscience 2004;127(3):649-58.
2003: Hanna Ksiezak-Reding; Han Kyoung Pyo; Boris Feinstein; Giulio Maria Pasinetti
Akt/PKB kinase phosphorylates separately Thr212 and Ser214 of tau protein in vitro.
Biochimica et biophysica acta 2003;1639(3):159-68.
2003: Rudy Zhao; Lap Ho; J Suh; Weiping Qin; H Pyo; Patrick N Pompl; Hanna Ksiezak-Reding; Giulio Maria Pasinetti
A role of P301L tau mutant in anti-apoptotic gene expression, cell cycle and apoptosis.
Molecular and cellular neurosciences 2003;24(2):367-79.
2003: Hanna Ksiezak-Reding; Muhammad Farooq; Liang-sheng Yang; dennis dickson; Patrizia LoPresti
Tau protein expression in adult bovine oligodendrocytes: functional and pathological significance.
Neurochemical research 2003;28(9):1385-92.
2002: Makio Takahashi; Karen M Weidenheim; dennis dickson; Hanna Ksiezak-Reding
Morphological and biochemical correlations of abnormal tau filaments in progressive supranuclear palsy.
Journal of neuropathology and experimental neurology 2002;61(1):33-45.
2001: ME King; Nupur Ghoshal; Joseph S Wall; Lester I Binder; Hanna Ksiezak-Reding
Structural analysis of Pick's disease-derived and in vitro-assembled tau filaments.
The American journal of pathology 2001;158(4):1481-90.
2000: Hanna Ksiezak-Reding; D He; Wanda Gordon-Krajcer; Yvonne Kress; Sunhee C Lee; dennis dickson
Induction of Alzheimer-specific Tau epitope AT100 in apoptotic human fetal astrocytes.
Cell motility and the cytoskeleton 2000;47(3):236-52.
2000: K Ishizawa; Hanna Ksiezak-Reding; Peter Davies; André Delacourte; P Tiseo; Shu-Hui C. Yen; dennis dickson
A double-labeling immunohistochemical study of tau exon 10 in Alzheimer's disease, progressive supranuclear palsy and Pick's disease.
Acta neuropathologica 2000;100(3):235-44.
2000: Wanda Gordon-Krajcer; L Yang; Hanna Ksiezak-Reding
Conformation of paired helical filaments blocks dephosphorylation of epitopes shared with fetal tau except Ser199/202 and Ser202/Thr205.
Brain research 2000;856(1-2):163-75.
2000: dennis dickson; WK Liu; Hanna Ksiezak-Reding; Shu-Hui C. Yen
Neuropathologic and molecular considerations.
Advances in neurology 2000;82():9-27.
1999: Liang-sheng Yang; Hanna Ksiezak-Reding
Ca2+ and Mg2+ selectively induce aggregates of PHF-tau but not normal human tau.
Journal of neuroscience research 1999;55(1):36-43.
1998: Hanna Ksiezak-Reding; G Yang; M Simon; Joseph S Wall
Assembled tau filaments differ from native paired helical filaments as determined by scanning transmission electron microscopy (STEM).
Brain research 1998;814(1-2):86-98.
1998: L Yang; Hanna Ksiezak-Reding
Ubiquitin immunoreactivity of paired helical filaments differs in Alzheimer's disease and corticobasal degeneration.
Acta neuropathologica 1998;96(5):520-6.
1997: E Tracz; dennis dickson; J F Hainfeld; Hanna Ksiezak-Reding
Paired helical filaments in corticobasal degeneration: the fine fibrillary structure with NanoVan.
Brain research 1997;773(1-2):33-44.
1997: Liang-sheng Yang; Wanda Gordon-Krajcer; Hanna Ksiezak-Reding
Tau released from paired helical filaments with formic acid or guanidine is susceptible to calpain-mediated proteolysis.
Journal of neurochemistry 1997;69(4):1548-58.
1996: Hanna Ksiezak-Reding; E Tracz; L S Yang; dennis dickson; M Simon; J S Wall
Ultrastructural instability of paired helical filaments from corticobasal degeneration as examined by scanning transmission electron microscopy.
The American journal of pathology 1996;149(2):639-51.
1995: Hanna Ksiezak-Reding; R L Leibowitz; R Bowser; Peter Davies
Binding of Alz 50 depends on Phe8 in tau synthetic peptides and varies between native and denatured tau proteins.
Brain research 1995;697(1-2):63-75.
1995: L S Yang; Hanna Ksiezak-Reding
Calpain-induced proteolysis of normal human tau and tau associated with paired helical filaments.
European journal of biochemistry / FEBS 1995;233(1):9-17.
1995: Hanna Ksiezak-Reding; Bridget Shafit-Zagardo; Shu-Hui C. Yen
Differential expression of exons 10 and 11 in normal tau and tau associated with paired helical filaments.
Journal of neuroscience research 1995;41(5):583-93.
1995: M B Feany; Hanna Ksiezak-Reding; W K Liu; I Vincent; Shu-Hui C. Yen; dennis dickson
Epitope expression and hyperphosphorylation of tau protein in corticobasal degeneration: differentiation from progressive supranuclear palsy.
Acta neuropathologica 1995;90(1):37-43.
1994: Hanna Ksiezak-Reding; K Morgan; L A Mattiace; Peter Davies; W K Liu; Shu-Hui C. Yen; Karen M Weidenheim; dennis dickson
Ultrastructure and biochemical composition of paired helical filaments in corticobasal degeneration.
The American journal of pathology 1994;145(6):1496-508.
1994: Hanna Ksiezak-Reding; K Morgan; dennis dickson
Tau immunoreactivity and SDS solubility of two populations of paired helical filaments that differ in morphology.
Brain research 1994;649(1-2):185-96.
1994: Hanna Ksiezak-Reding; J S Wall
Mass and physical dimensions of two distinct populations of paired helical filaments.
Neurobiology of aging 1994;15(1):11-9.
1992: Hanna Ksiezak-Reding; W K Liu; Shu-Hui C. Yen
Phosphate analysis and dephosphorylation of modified tau associated with paired helical filaments.
Brain research 1992;597(2):209-19.
1992: dennis dickson; Hanna Ksiezak-Reding; W K Liu; Peter Davies; A Crowe; Shu-Hui C. Yen
Immunocytochemistry of neurofibrillary tangles with antibodies to subregions of tau protein: identification of hidden and cleaved tau epitopes and a new phosphorylation site.
Acta neuropathologica 1992;84(6):596-605.
1991: A Crowe; Hanna Ksiezak-Reding; W K Liu; dennis dickson; Shu-Hui C. Yen
The N terminal region of human tau is present in Alzheimer's disease protein A68 and is incorporated into paired helical filaments.
The American journal of pathology 1991;139(6):1463-70.
1991: W K Liu; Hanna Ksiezak-Reding; Shu-Hui C. Yen
Abnormal tau proteins from Alzheimer's disease brains. Purification and amino acid analysis.
The Journal of biological chemistry 1991;266(32):21723-7.
1991: L A Mattiace; Yvonne Kress; Peter Davies; Hanna Ksiezak-Reding; Shu-Hui C. Yen; dennis dickson
Ubiquitin-immunoreactive dystrophic neurites in Down's syndrome brains.
Journal of neuropathology and experimental neurology 1991;50(5):547-59.
1991: Hanna Ksiezak-Reding; Shu-Hui C. Yen
Structural stability of paired helical filaments requires microtubule-binding domains of tau: a model for self-association.
Neuron 1991;6(5):717-28.
1990: T Suenaga; Asao Hirano; Josefina F Llena; Hanna Ksiezak-Reding; Shu-Hui C. Yen; dennis dickson
Ubiquitin immunoreactivity in kuru plaques in Creutzfeldt-Jakob disease.
Annals of neurology 1990;28(2):174-7.
1990: dennis dickson; A Wertkin; Yvonne Kress; Hanna Ksiezak-Reding; Shu-Hui C. Yen
Ubiquitin immunoreactive structures in normal human brains. Distribution and developmental aspects.
Laboratory investigation; a journal of technical methods and pathology 1990;63(1):87-99.
1990: Hanna Ksiezak-Reding; L I Binder; Shu-Hui C. Yen
Alzheimer disease proteins (A68) share epitopes with tau but show distinct biochemical properties.
Journal of neuroscience research 1990;25(3):420-30.
1990: Hanna Ksiezak-Reding; C H Chien; Virginia M-Y Lee; Shu-Hui C. Yen
Mapping of the Alz 50 epitope in microtubule-associated proteins tau.
Journal of neuroscience research 1990;25(3):412-9.
1990: T Suenaga; Asao Hirano; Josefina F Llena; Hanna Ksiezak-Reding; Shu-Hui C. Yen; dennis dickson
Modified Bielschowsky and immunocytochemical studies on cerebellar plaques in Alzheimer's disease.
Journal of neuropathology and experimental neurology 1990;49(1):31-40.
1989: Sunhee C Lee; Yong D Park; Shu-Hui C. Yen; Hanna Ksiezak-Reding; James E Goldman; dennis dickson
A study of infantile motor neuron disease with neurofilament and ubiquitin immunocytochemistry.
Neuropediatrics 1989;20(2):107-11.
1989: dennis dickson; H Crystal; L A Mattiace; Yvonne Kress; A Schwagerl; Hanna Ksiezak-Reding; Peter Davies; Shu-Hui C. Yen
Diffuse Lewy body disease: light and electron microscopic immunocytochemistry of senile plaques.
Acta neuropathologica 1989;78(6):572-84.
1988: Hanna Ksiezak-Reding; L I Binder; Shu-Hui C. Yen
Immunochemical and biochemical characterization of tau proteins in normal and Alzheimer's disease brains with Alz 50 and Tau-1.
The Journal of biological chemistry 1988;263(17):7948-53.
1988: Hanna Ksiezak-Reding; Peter Davies; Shu-Hui C. Yen
Alz 50, a monoclonal antibody to Alzheimer's disease antigen, cross-reacts with tau proteins from bovine and normal human brain.
The Journal of biological chemistry 1988;263(17):7943-7.
1987: Hanna Ksiezak-Reding; Shu-Hui C. Yen
Phosphatase and carbocyanine dye binding define different types of phosphate groups in mammalian neurofilaments.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(11):3554-60.
1987: Hanna Ksiezak-Reding; dennis dickson; Peter Davies; Shu-Hui C. Yen
Recognition of tau epitopes by anti-neurofilament antibodies that bind to Alzheimer neurofibrillary tangles.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(10):3410-4.
1987: Hanna Ksiezak-Reding; Shu-Hui C. Yen
Two monoclonal antibodies recognize Alzheimer's neurofibrillary tangles, neurofilament, and microtubule-associated proteins.
Journal of neurochemistry 1987;48(2):455-62.
1987: dennis dickson; Hanna Ksiezak-Reding; Peter Davies; Shu-Hui C. Yen
A monoclonal antibody that recognizes a phosphorylated epitope in Alzheimer neurofibrillary tangles, neurofilaments and tau proteins immunostains granulovacuolar degeneration.
Acta neuropathologica 1987;73(3):254-8.
1986: L M Hinman; Hanna Ksiezak-Reding; A C Baker; John P Blass
Pigeon liver phosphoprotein phosphatase: an effective activator of pyruvate dehydrogenase in tissue homogenates.
Archives of biochemistry and biophysics 1986;246(1):381-90.
1984: Hanna Ksiezak-Reding; C Peterson; G E Gibson
The pyruvate dehydrogenase complex during aging.
Mechanisms of ageing and development 1984;26(1):67-73.
1984: G E Gibson; Hanna Ksiezak-Reding; K F Sheu; V Mykytyn; John P Blass
Correlation of enzymatic, metabolic, and behavioral deficits in thiamin deficiency and its reversal.
Neurochemical research 1984;9(6):803-14.
1982: Hanna Ksiezak-Reding; John P Blass; G E Gibson
Studies on the pyruvate dehydrogenase complex in brain with the arylamine acetyltransferase-coupled assay.
Journal of neurochemistry 1982;38(6):1627-36.
1982: Hanna Ksiezak-Reding; Alan M Goldberg
The role of chloride in acetylcholine metabolism.
Journal of neurochemistry 1982;38(1):121-9.