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Jian Kuang

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Chemicals & Drugs

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Ruoning Wang; Sung Yun Jung; Chuan Fen Wu; Jun Qin; Ryuji Kobayashi; Gary E Gallick; Jian Kuang
Direct roles of the signaling kinase RSK2 in Cdc25C activation during Xenopus oocyte maturation.
P Ji; S M Smith; Yan Wang; Rongcai Jiang; Sonya W Song; B Li; Raymond Sawaya; Janet M Bruner; Jian Kuang; H Yu; Gregory N Fuller; Wei Zhang
Inhibition of gliomagenesis and attenuation of mitotic transition by MIIP.
Chuan Fen Wu; Ruoning Wang; Qianjin Liang; Jianjiao Liang; Wenke Li; Sung Yun Jung; Jun Qin; Sue-Hwa Lin; Jian Kuang
Dissecting the M phase-specific phosphorylation of serine-proline or threonine-proline motifs.

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All Publications

2010: Ruoning Wang; Sung Yun Jung; Chuan Fen Wu; Jun Qin; Ryuji Kobayashi; Gary E Gallick; Jian Kuang
Direct roles of the signaling kinase RSK2 in Cdc25C activation during Xenopus oocyte maturation.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(46):19885-90.
2010: P Ji; S M Smith; Yan Wang; Rongcai Jiang; Sonya W Song; B Li; Raymond Sawaya; Janet M Bruner; Jian Kuang; H Yu; Gregory N Fuller; Wei Zhang
Inhibition of gliomagenesis and attenuation of mitotic transition by MIIP.
Oncogene 2010;29(24):3501-8.
2010: Chuan Fen Wu; Ruoning Wang; Qianjin Liang; Jianjiao Liang; Wenke Li; Sung Yun Jung; Jun Qin; Sue-Hwa Lin; Jian Kuang
Dissecting the M phase-specific phosphorylation of serine-proline or threonine-proline motifs.
Molecular biology of the cell 2010;21(9):1470-81.
2009: Xi Zhou; Shujuan Pan; Le Sun; Joe Corvera; Yu-Chen Lee; Sue-Hwa Lin; Jian Kuang
The CHMP4b- and Src-docking sites in the Bro1 domain are autoinhibited in the native state of Alix.
The Biochemical journal 2009;418(2):277-84.
2008: Xi Zhou; Shujuan Pan; Le Sun; Joe Corvera; Sue-Hwa Lin; Jian Kuang
The HIV-1 p6/EIAV p9 docking site in Alix is autoinhibited as revealed by a conformation-sensitive anti-Alix monoclonal antibody.
The Biochemical journal 2008;414(2):215-20.
2008: Shujuan Pan; Ruoning Wang; Xi Zhou; Joe Corvera; Malgorzata Kloc; Richard Sifers; Gary E Gallick; Sue-Hwa Lin; Jian Kuang
Extracellular Alix regulates integrin-mediated cell adhesions and extracellular matrix assembly.
The EMBO journal 2008;27(15):2077-90.
2008: Yong Zhao; Olivier Haccard; Ruoning Wang; Jiangtao Yu; Jian Kuang; Catherine Jessus; Michael L Goldberg
Roles of Greatwall kinase in the regulation of cdc25 phosphatase.
Molecular biology of the cell 2008;19(4):1317-27.
2007: Zhehui Feng; Chuan-Fen Wu; Xi Zhou; Jian Kuang
Alternative polyadenylation produces two major transcripts of Alix.
Archives of biochemistry and biophysics 2007;465(2):328-35.
2007: Chuan-Fen Wu; Claude Delsert; Sandrine Faure; Edwin E Traverso; Malgorzata Kloc; Jian Kuang; Laurence D Etkin; Nathalie Morin
Tumorhead distribution to cytoplasmic membrane of neural plate cells is positively regulated by Xenopus p21-activated kinase 1 (X-PAK1).
Developmental biology 2007;308(1):169-86.
2007: Ruoning Wang; Guangan He; Mayra Nelman-Gonzalez; Cheryl L Ashorn; Gary E Gallick; P Todd Stukenberg; Marc W Kirschner; Jian Kuang
Regulation of Cdc25C by ERK-MAP kinases during the G2/M transition.
Cell 2007;128(6):1119-32.
2007: Robert E Dejournett; Ryuji Kobayashi; Shujuan Pan; Chuanfen Wu; Laurence D Etkin; Richard B Clark; Oliver Bogler; Jian Kuang
Phosphorylation of the proline-rich domain of Xp95 modulates Xp95 interaction with partner proteins.
The Biochemical journal 2007;401(2):521-31.
2006: Guangan He; Jian Kuang; Zaifeng Huang; John M Koomen; Ryuji Kobayashi; Abdul R Khokhar; Zahid H Siddik
Upregulation of p27 and its inhibition of CDK2/cyclin E activity following DNA damage by a novel platinum agent are dependent on the expression of p21.
British journal of cancer 2006;95(11):1514-24.
2006: Shujuan Pan; Ruoning Wang; Xi Zhou; Guangan He; John M Koomen; Ryuji Kobayashi; Le Sun; Joe Corvera; Gary E Gallick; Jian Kuang
Involvement of the conserved adaptor protein Alix in actin cytoskeleton assembly.
The Journal of biological chemistry 2006;281(45):34640-50.
2005: Guangan He; Zahid H Siddik; Zaifeng Huang; Ruoning Wang; John M Koomen; Ryuji Kobayashi; Abdul R Khokhar; Jian Kuang
Induction of p21 by p53 following DNA damage inhibits both Cdk4 and Cdk2 activities.
Oncogene 2005;24(18):2929-43.
2004: Sue-Hwa Lin; Michiya Nishino; Weiping Luo; Jonathan P Aumais; Matthew Galfione; Jian Kuang; Li-Yuan Yu-Lee
Inhibition of prostate tumor growth by overexpression of NudC, a microtubule motor-associated protein.
Oncogene 2004;23(14):2499-506.
2002: Ying Wu; Shujuan Pan; Weiping Luo; Sue-Hwa Lin; Jian Kuang
Hp95 promotes anoikis and inhibits tumorigenicity of HeLa cells.
Oncogene 2002;21(44):6801-8.
2002: Margaret A Bolton; Weijie Lan; Shannon E Powers; Mark L McCleland; Jian Kuang; P Todd Stukenberg
Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation.
Molecular biology of the cell 2002;13(9):3064-77.
2001: Jian Kuang; Guangan He; Zaifeng Huang; Abdul R Khokhar; Zahid H Siddik
Bimodal effects of 1R,2R-diaminocyclohexane(trans-diacetato)(dichloro)platinum(IV) on cell cycle checkpoints.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(11):3629-39.
2001: Chuan-Fen Wu; H Nakamura; Agnes P Chan; Y H Zhou; Tongyu Cao; Jian Kuang; S G Gong; G He; Laurence D Etkin
Tumorhead, a Xenopus gene product that inhibits neural differentiation through regulation of proliferation.
Development (Cambridge, England) 2001;128(17):3381-93.
2001: Y Wu; S Pan; S Che; Guangan He; Mayra Nelman-Gonzalez; Michael M Weil; Jian Kuang
Overexpression of Hp95 induces G1 phase arrest in confluent HeLa cells.
Differentiation; research in biological diversity 2001;67(4-5):139-53.
2000: H Nakamura; C Wu; Jian Kuang; Carolyn A Larabell; Laurence D Etkin
XCS-1, a maternally expressed gene product involved in regulating mitosis in Xenopus.
Journal of cell science 2000;113 ( Pt 13)():2497-505.
1999: S Che; Heithem M El-Hodiri; C F Wu; Mayra Nelman-Gonzalez; Michael M Weil; Laurence D Etkin; R B Clark; Jian Kuang
Identification and cloning of xp95, a putative signal transduction protein in Xenopus oocytes.
The Journal of biological chemistry 1999;274(9):5522-31.
1998: H Zhou; Jian Kuang; L Zhong; Wen-Lin Kuo; Joe Gray; A Sahin; B R Brinkley; Subrata Sen
Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation.
Nature genetics 1998;20(2):189-93.
1998: R A Barratt; Gary D Kao; W Gillies McKenna; Jian Kuang; Ruth J Muschel
The G2 block induced by DNA damage: a caffeine-resistant component independent of Cdc25C, MPM-2 phosphorylation, and H1 kinase activity.
Cancer research 1998;58(12):2639-45.
1998: S Che; Weiguo Wu; Mayra Nelman-Gonzalez; T Stukenberg; R Clark; Jian Kuang
A phosphatase activity in Xenopus oocyte extracts preferentially dephosphorylates the MPM-2 epitope.
FEBS letters 1998;424(3):225-33.
1997: Michael B Yaffe; Mike Schutkowski; M Shen; Xiao Zhen Zhou; P Todd Stukenberg; JU Rahfeld; J Xu; Jian Kuang; Marc W Kirschner; Gunter Fischer; Lewis C Cantley; Kun Ping Lu
Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism.
Science (New York, N.Y.) 1997;278(5345):1957-60.
1997: S Che; Michael M Weil; Laurence D Etkin; H F Epstein; Jian Kuang
Molecular cloning of a splice variant of Caenorhabditis elegans YNK1, a putative element in signal transduction.
Biochimica et biophysica acta 1997;1354(3):231-40.
1997: S Che; Michael M Weil; Mayra Nelman-Gonzalez; Cheryl L Ashorn; Jian Kuang
MPM-2 epitope sequence is not sufficient for recognition and phosphorylation by ME kinase-H.
FEBS letters 1997;413(3):417-23.
1997: Heithem M El-Hodiri; S Che; Mayra Nelman-Gonzalez; Jian Kuang; Laurence D Etkin
Mitogen-activated protein kinase and cyclin B/Cdc2 phosphorylate Xenopus nuclear factor 7 (xnf7) in extracts from mature oocytes. Implications for regulation of xnf7 subcellular localization.
The Journal of biological chemistry 1997;272(33):20463-70.
1997: P Todd Stukenberg; KD Lustig; TJ McGarry; Randall W King; Jian Kuang; Marc W Kirschner
Systematic identification of mitotic phosphoproteins.
Current biology : CB 1997;7(5):338-48.
1996: W Shou; X Li; C Wu; Tongyu Cao; Jian Kuang; S Che; Laurence D Etkin
Finely tuned regulation of cytoplasmic retention of Xenopus nuclear factor 7 by phosphorylation of individual threonine residues.
Molecular and cellular biology 1996;16(3):990-7.
1994: Jian Kuang; C L Ashorn; M Gonzalez-Kuyvenhoven; J E Penkala
cdc25 is one of the MPM-2 antigens involved in the activation of maturation-promoting factor.
Molecular biology of the cell 1994;5(2):135-45.
1993: Jian Kuang; C L Ashorn
At least two kinases phosphorylate the MPM-2 epitope during Xenopus oocyte maturation.
The Journal of cell biology 1993;123(4):859-68.
1991: Jian Kuang; J E Penkala; C L Ashorn; D A Wright; G F Saunders; P N Rao
Multiple forms of maturation-promoting factor in unfertilized Xenopus eggs.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(24):11530-4.
1991: Jian Kuang; J E Penkala; D A Wright; G F Saunders; P N Rao
A novel M phase-specific H1 kinase recognized by the mitosis-specific monoclonal antibody MPM-2.
Developmental biology 1991;144(1):54-64.
1989: Jian Kuang; J Zhao; D A Wright; G F Saunders; P N Rao
Mitosis-specific monoclonal antibody MPM-2 inhibits Xenopus oocyte maturation and depletes maturation-promoting activity.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(13):4982-6.
1989: J Y Zhao; Jian Kuang; R C Adlakha; P N Rao
Threonine phosphorylation is associated with mitosis in HeLa cells.
FEBS letters 1989;249(2):389-95.