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Jürgen Kuball

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Cordula Gründer; Sabine Heijhuurs; Samantha Hol; Anton Martens; Wouter Scheper; Kirsten Scholten; Zsolt Sebestyen; Trudy Straetemans; Roland Strong; Suzanne van Dorp; Esther Drent; Jürgen Kuball
γ9 and δ2CDR3 domains regulate functional avidity of T cells harboring γ9δ2TCRs.
Christelle Harly; Thomas Herrmann; Jürgen Kuball; Alexandra Léger; Jianqiang Li; Hannu Mönkkönen; Jukka Mönkkönen; Steven Nedellec; Sonia Netzer; Daniel Olive; Cassie-Marie Peigné; Erin J Adams; Marc Bonneville; Richard Breathnach; Julie Déchanet-Merville; Yves Guillaume; Emmanuel Scotet
Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset.
Christoph Schmid; Gerard Socie; Michael Stadler; Reza Tabrizi; Lars Vindeløv; Jiri Vorlicek; Luca Castagna; Jan Cornelissen; Michele Falda; Graham Jackson; Nicolaus Kröger; Jürgen Kuball; Myriam Labopin; Per Ljungman; Mohamad Mohty; Arnon Nagler; Dietger Niederwieser; Emmanuelle Polge; Andreas Rank; Vanderson Rocha
Treatment, risk factors, and outcome of adults with relapsed AML after reduced intensity conditioning for allogeneic stem cell transplantation.

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All Publications

2012: Cordula Gründer; Sabine Heijhuurs; Samantha Hol; Anton Martens; Wouter Scheper; Kirsten Scholten; Zsolt Sebestyen; Trudy Straetemans; Roland Strong; Suzanne van Dorp; Esther Drent; Jürgen Kuball
γ9 and δ2CDR3 domains regulate functional avidity of T cells harboring γ9δ2TCRs.
Blood 2012;120(26):5153-62.
2012: Christelle Harly; Thomas Herrmann; Jürgen Kuball; Alexandra Léger; Jianqiang Li; Hannu Mönkkönen; Jukka Mönkkönen; Steven Nedellec; Sonia Netzer; Daniel Olive; Cassie-Marie Peigné; Erin J Adams; Marc Bonneville; Richard Breathnach; Julie Déchanet-Merville; Yves Guillaume; Emmanuel Scotet
Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset.
Blood 2012;120(11):2269-79.
2012: Christoph Schmid; Gerard Socie; Michael Stadler; Reza Tabrizi; Lars Vindeløv; Jiri Vorlicek; Luca Castagna; Jan Cornelissen; Michele Falda; Graham Jackson; Nicolaus Kröger; Jürgen Kuball; Myriam Labopin; Per Ljungman; Mohamad Mohty; Arnon Nagler; Dietger Niederwieser; Emmanuelle Polge; Andreas Rank; Vanderson Rocha
Treatment, risk factors, and outcome of adults with relapsed AML after reduced intensity conditioning for allogeneic stem cell transplantation.
Blood 2012;119(6):1599-606.
2011: Suzanne van Dorp; Scott J P Beijn; Roel de Weger; Saskia Ebeling; Frits Gmelig-Meyling; Edward F Knol; Henk Lokhorst; Ellen Meijer; Monique Minnema; Eefke Petersen; Floor Pietersma; Henrike Resemann; Liane te Boome; Debbie Van Baarle; Marijke van Dijk; Jürgen Kuball
The immunological phenotype of rituximab-sensitive chronic graft-versus-host disease: a phase II study.
Haematologica 2011;96(9):1380-4.
2011: Victoria Marcu (-Malina); Anton Martens; Kirsten Scholten; Zsolt Sebestyen; Susanne Strand; Marit van Buuren; Linda Hartkamp; Sabine Heijhuurs; Jürgen Kuball
Redirecting αβ T cells against cancer cells by transfer of a broadly tumor-reactive γδT-cell receptor.
Blood 2011;118(1):50-9.
2011: Floor L Pietersma; Suzanne van Dorp; Monique C Minnema; Jürgen Kuball; Ellen Meijer; Rob Schuurman; Debbie Van Baarle
Influence of donor cytomegalovirus (CMV) status on severity of viral reactivation after allogeneic stem cell transplantation in CMV-seropositive recipients.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2011;52(7):e144-8.
2011: Jürgen Kuball; Karin de Boer; Eva Wagner; Mohammed Wattad; Edite Antunes; Risini D Weeratna; Alain P Vicari; Carina Lotz; Suzanne van Dorp; Samantha Hol; Philip D Greenberg; Wolfgang Heit; Heather L Davis; Matthias Theobald
Pitfalls of vaccinations with WT1-, Proteinase3- and MUC1-derived peptides in combination with MontanideISA51 and CpG7909.
Cancer immunology, immunotherapy : CII 2011;60(2):161-71.
2010: Anjo Riemens; Liane te Boome; Saskia Imhof; Jürgen Kuball; Aniki Rothova
Current insights into ocular graft-versus-host disease.
Current opinion in ophthalmology 2010;21(6):485-94.
2010: Ralf-Holger Voss; Simone Thomas; Christina Pfirschke; Beate Hauptrock; Sebastian Klobuch; Jürgen Kuball; Margarete Grabowski; Renate Engel; Philippe Guillaume; Pedro Romero; Christoph Huber; Philipp Beckhove; Matthias Theobald
Coexpression of the T-cell receptor constant alpha domain triggers tumor reactivity of single-chain TCR-transduced human T cells.
Blood 2010;115(25):5154-63.
2009: Suzanne van Dorp; Floor Pietersma; Matthias Wölfl; Leo F Verdonck; Eefke J Petersen; Henk M Lokhorst; Edwin Martens; Matthias Theobald; Debbie Van Baarle; Ellen Meijer; Jürgen Kuball
Rituximab treatment before reduced-intensity conditioning transplantation associates with a decreased incidence of extensive chronic GVHD.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2009;15(6):671-8.
2009: Victoria Marcu (-Malina); Suzanne van Dorp; Jürgen Kuball
Re-targeting T-cells against cancer by gene-transfer of tumor-reactive receptors.
Expert opinion on biological therapy 2009;9(5):579-91.
2009: Jürgen Kuball; Beate Hauptrock; Victoria Marcu (-Malina); Edite Antunes; Ralf-Holger Voss; Matthias Wolfl; Roland Strong; Matthias Theobald; Philip D Greenberg
Increasing functional avidity of TCR-redirected T cells by removing defined N-glycosylation sites in the TCR constant domain.
The Journal of experimental medicine 2009;206(2):463-75.
2008: Matthias Wölfl; Alleluiah Rutebemberwa; Timothy Mosbruger; Qing Mao; Hong-mei Li; Dale Netski; Stuart C Ray; Drew M Pardoll; John Sidney; Alessandro Sette; Todd Allen; Thomas Kuntzen; Daniel G Kavanagh; Jürgen Kuball; Philip D Greenberg; Andrea L Cox
Hepatitis C virus immune escape via exploitation of a hole in the T cell repertoire.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(9):6435-46.
2008: Marcus Schuchmann; Ralf G Meyer; E Distler; Esther Von Stebut; Jürgen Kuball; Elke Schnürer; T Wölfel; M Theobald; Abdo Konur; S Gregor; O Schreiner; Christoph Huber; Peter R Galle; Gerd Otto; Wolfgang Herr
The programmed death (PD)-1/PD-ligand 1 pathway regulates graft-versus-host-reactive CD8 T cells after liver transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008;8(11):2434-44.
2008: Matthias Wölfl; Jürgen Kuball; Matthias Eyrich; Paul G Schlegel; Philip D Greenberg
Use of CD137 to study the full repertoire of CD8+ T cells without the need to know epitope specificities.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2008;73(11):1043-9.
2008: Ralf-Holger Voss; Ralph A Willemsen; Jürgen Kuball; Margarete Grabowski; Renate Engel; Ratna S Intan; Philippe Guillaume; Pedro Romero; Christoph Huber; Matthias Theobald
Molecular design of the Calphabeta interface favors specific pairing of introduced TCRalphabeta in human T cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(1):391-401.
2007: Matthias Wolfl; Jürgen Kuball; William Y Ho; Hieu Nguyen; Thomas J Manley; Marie Bleakley; Philip D Greenberg
Activation-induced expression of CD137 permits detection, isolation, and expansion of the full repertoire of CD8+ T cells responding to antigen without requiring knowledge of epitope specificities.
Blood 2007;110(1):201-10.
2007: Katrin Besold; Nadine Frankenberg; Sandra Pepperl-Klindworth; Jürgen Kuball; Matthias Theobald; Gabriele Hahn; Bodo Plachter
Processing and MHC class I presentation of human cytomegalovirus pp65-derived peptides persist despite gpUS2-11-mediated immune evasion.
The Journal of general virology 2007;88(Pt 5):1429-39.
2007: Jürgen Kuball; Michelle L Dossett; Matthias Wolfl; William Y Ho; Ralf-Holger Voss; Carla Fowler; Philip D Greenberg
Facilitating matched pairing and expression of TCR chains introduced into human T cells.
Blood 2007;109(6):2331-8.
2006: Christian Blank; Jürgen Kuball; Simon Voelkl; Heinz Wiendl; Bernd Becker; Bernhard Walter; Otto Majdic; Thomas F Gajewski; Matthias Theobald; Reinhard Andreesen; Andreas Mackensen
Blockade of PD-L1 (B7-H1) augments human tumor-specific T cell responses in vitro.
International journal of cancer. Journal international du cancer 2006;119(2):317-27.
2006: Zhanhai Su; Jürgen Kuball; Ana P Barreiros; Daniela Gottfried; Edite Antunes Ferreira; Matthias Theobald; Peter R Galle; Dennis Strand; Susanne Strand
Nitric oxide promotes resistance to tumor suppression by CTLs.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(7):3923-30.
2006: William Y Ho; Hieu N Nguyen; Matthias Wolfl; Jürgen Kuball; Philip D Greenberg
In vitro methods for generating CD8+ T-cell clones for immunotherapy from the naïve repertoire.
Journal of immunological methods 2006;310(1-2):40-52.
2006: Ralf-Holger Voss; Jürgen Kuball; Renate Engel; Philippe Guillaume; Pedro Romero; Christoph Huber; Matthias Theobald
Redirection of T cells by delivering a transgenic mouse-derived MDM2 tumor antigen-specific TCR and its humanized derivative is governed by the CD8 coreceptor and affects natural human TCR expression.
Immunologic research 2006;34(1):67-87.
2006: Sandra Pepperl-Klindworth; Katrin Besold; Nadine Frankenberg; Mildred Farkas; Jürgen Kuball; Matthias Theobald; Bodo Plachter
Cytomegalovirus interleukin-10 expression in infected cells does not impair MHC class I restricted peptide presentation on bystanding antigen-presenting cells.
Viral immunology 2006;19(1):92-101.
2005: Christoph Huber; N Bobek; Jürgen Kuball; S Thaler; Sandra Hoffarth; C Huber; Matthias Theobald; Martin Schuler
Inhibitors of apoptosis confer resistance to tumour suppression by adoptively transplanted cytotoxic T-lymphocytes in vitro and in vivo.
Cell death and differentiation 2005;12(4):317-25.
2005: Jürgen Kuball; Frank W Schmitz; Ralf-Holger Voss; Edite Antunes Ferreira; Renate Engel; Philippe Guillaume; Susanne Strand; Pedro Romero; Christoph Huber; Linda A Sherman; Matthias Theobald
Cooperation of human tumor-reactive CD4+ and CD8+ T cells after redirection of their specificity by a high-affinity p53A2.1-specific TCR.
Immunity 2005;22(1):117-29.
2005: Ralf-Holger Voss; Jürgen Kuball; Matthias Theobald
Designing TCR for cancer immunotherapy.
Methods in molecular medicine 2005;109():229-56.
2004: Jürgen Kuball; Matthias Theobald; Edite Antunes Ferreira; Georg Hess; Jürgen Burg; Giancarlo Maccagno; Ana P Barreiros; Stefan Lüth; Carl C Schimanski; Marcus Schuchmann; Andreas Schwarting; Markus F Neurath; Gerd Otto; Peter R Galle; Ansgar W Lohse
Control of organ transplant-associated graft-versus-host disease by activated host lymphocyte infusions.
Transplantation 2004;78(12):1774-9.
2004: Susanne Strand; Petra Vollmer; Lothar van den Abeelen; Daniela Gottfried; Vijay Alla; Hans Heid; Jürgen Kuball; Matthias Theobald; Peter R Galle; Dennis Strand
Cleavage of CD95 by matrix metalloproteinase-7 induces apoptosis resistance in tumour cells.
Oncogene 2004;23(20):3732-6.
2002: Jürgen Kuball; Martin Schuler; E Antunes Ferreira; Wolfgang Herr; M Neumann; L Obenauer-Kutner; L Westreich; Christoph Huber; Thomas Wölfel; Matthias Theobald
Generating p53-specific cytotoxic T lymphocytes by recombinant adenoviral vector-based vaccination in mice, but not man.
Gene therapy 2002;9(13):833-43.
2002: Jürgen Kuball; Hans Günter Derigs; Thomas Wölfel
[T-cell therapy in oncology. Therapeutic vaccination, allogeneic blood stem cell transplantation and adoptive T-cell transfer].
Deutsche medizinische Wochenschrift (1946) 2002;127(14):755-62.
2002: Jürgen Kuball; Shu Fen Wen; Joachim Leissner; Derek Atkins; Patricia Meinhardt; Erlinda Quijano; Heidrun Engler; Beth Hutchins; Daniel Maneval; Michael J Grace; Mary Ann Fritz; Stephan Störkel; Joachim W Thüroff; Christoph Huber; Martin Schuler
Successful adenovirus-mediated wild-type p53 gene transfer in patients with bladder cancer by intravesical vector instillation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(4):957-65.
2001: Jürgen Kuball; Christoph Huber; Martin Schuler
[Gene therapy of solid tumors].
Der Internist 2001;42(10):1321-7.
2001: T Stanislawski; Ralf-Holger Voss; Carina Lotz; Elena Sadovnikova; Ralph A Willemsen; Jürgen Kuball; Thomas Ruppert; Reinder L H Bolhuis; Cornelis J M Melief; Christoph Huber; Hans J Stauss; Matthias Theobald
Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer.
Nature immunology 2001;2(10):962-70.
2001: Martin Schuler; Richard Herrmann; J L De Greve; A K Stewart; U Gatzemeier; D J Stewart; L Laufman; Richard J Gralla; Jürgen Kuball; R Buhl; Claus Peter Heussel; Friedrich Kommoss; A P Perruchoud; F A Shepherd; Mary Ann Fritz; J A Horowitz; Christoph Huber; C Rochlitz
Adenovirus-mediated wild-type p53 gene transfer in patients receiving chemotherapy for advanced non-small-cell lung cancer: results of a multicenter phase II study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(6):1750-8.