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Paul Kubes

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TOP 3
Craig N Jenne; R Urrutia; Paul Kubes
Platelets: bridging hemostasis, inflammation, and immunity.
Daniel J Niven; Henry Thomas Stelfox; Paul Kubes; Caroline Léger; Kevin B Laupland
Assessment of the safety and feasibility of administering antipyretic therapy in critically ill adults: A pilot randomized clinical trial.
Connie H Y Wong; Paul Kubes
Imaging natural killer T cells in action.

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All Publications

2013: Craig N Jenne; R Urrutia; Paul Kubes
Platelets: bridging hemostasis, inflammation, and immunity.
International journal of laboratory hematology 2013;35(3):254-61.
2013: Daniel J Niven; Henry Thomas Stelfox; Paul Kubes; Caroline Léger; Kevin B Laupland
Assessment of the safety and feasibility of administering antipyretic therapy in critically ill adults: A pilot randomized clinical trial.
Journal of critical care 2013;28(3):296-302.
2013: Connie H Y Wong; Paul Kubes
Imaging natural killer T cells in action.
Immunology and cell biology 2013;91(4):304-10.
2013: Craig N Jenne; Peter A Forsyth; Braedon McDonald; Grant McFadden; Masmudur M Rahman; Connie H Y Wong; Franz J Zemp; Paul Kubes
Neutrophils recruited to sites of infection protect from virus challenge by releasing neutrophil extracellular traps.
Cell host & microbe 2013;13(2):169-80.
2013: Bryan G Yipp; Paul Kubes
Antibodies against neutrophil LY6G do not inhibit leukocyte recruitment in mice in vivo.
Blood 2013;121(1):241-2.
2012: Tara J Moriarty; Tanya Odisho; Aydan Salman-Dilgimen; Meiqing Shi; Jon T Skare; Eric H Weening; Jing Wu; Hong Zhou; Rhodaba Ebady; Pierre-Olivier Hardy; Paul Kubes; John Leong; Yi-Pin Lin; George Chaconas
Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules.
Molecular microbiology 2012;86(5):1116-31.
2012: Elzbieta Kolaczkowska; Paul Kubes
Phagocytes & granulocytes. Angiogenic neutrophils: a novel subpopulation paradigm.
Blood 2012;120(23):4455-7.
2012: Paul Kubes; Wajahat Z Mehal
Sterile inflammation in the liver.
Gastroenterology 2012;143(5):1158-72.
2012: Braedon McDonald; Rossana Urrutia; Bryan G Yipp; Craig N Jenne; Paul Kubes
Intravascular neutrophil extracellular traps capture bacteria from the bloodstream during sepsis.
Cell host & microbe 2012;12(3):324-33.
2012: Bryan G Yipp; Lori Zbytnuik; Kunyan Zhang; Muhammad Asaduzzaman; John Conly; Anne de Boisfleury Chevance; Craig N Jenne; Stephen E Malawista; H Christopher Meijndert; Björn Petri; Keir Pittman; Davide Salina; Brittney N V Scott; Kaiyu Wu; Paul Kubes
Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo.
Nature medicine 2012;18(9):1386-93.
2012: Jonathan D Spicer; Simon C Chow; Jonathan J Cools-Lartigue; Betty Giannias; Paul Kubes; Braedon McDonald; Lorenzo E Ferri
Neutrophils promote liver metastasis via Mac-1-mediated interactions with circulating tumor cells.
Cancer research 2012;72(16):3919-27.
2012: Shalina S Ousman; Paul Kubes
Immune surveillance in the central nervous system.
Nature neuroscience 2012;15(8):1096-101.
2012: Craig N Jenne; Paul Kubes
NETs tangle with HIV.
Cell host & microbe 2012;12(1):5-7.
2012: James A Deane; Latasha D Abeynaike; A Richard Kitching; Paul Kubes; M Ursula Norman; Janet L Wee; Michael J Hickey
Endogenous regulatory T cells adhere in inflamed dermal vessels via ICAM-1: association with regulation of effector leukocyte adhesion.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(5):2179-88.
2012: Maria-Jesus Sanz; Paul Kubes
Neutrophil-active chemokines in in vivo imaging of neutrophil trafficking.
European journal of immunology 2012;42(2):278-83.
2012: Mark Harding; Paul Kubes
Innate immunity in the vasculature: interactions with pathogenic bacteria.
Current opinion in microbiology 2012;15(1):85-91.
2012: Sean A Parsons; Pina Colarusso; Paul Kubes; Björn Petri; Dawn L Roccamatisi; Ritu Sharma; Hong Zhang; Kamala D Patel
Endothelial paxillin and focal adhesion kinase (FAK) play a critical role in neutrophil transmigration.
European journal of immunology 2012;42(2):436-46.
2012: Daniel J Niven; H Tom Stelfox; Paul Kubes; Caroline Léger; Kevin B Laupland
Assessment of the safety and feasibility of administering anti-pyretic therapy in critically ill adults: study protocol of a randomized trial.
BMC research notes 2012;5():147.
2012: Braedon McDonald; Paul Kubes
Neutrophils and intravascular immunity in the liver during infection and sterile inflammation.
Toxicologic pathology 2012;40(2):157-65.
2011: Braedon McDonald; Paul Kubes
Cellular and molecular choreography of neutrophil recruitment to sites of sterile inflammation.
Journal of molecular medicine (Berlin, Germany) 2011;89(11):1079-88.
2011: Connie H Y Wong; Craig N Jenne; Woo Yong Lee; Caroline Léger; Paul Kubes
Functional innervation of hepatic iNKT cells is immunosuppressive following stroke.
Science (New York, N.Y.) 2011;334(6052):101-5.
2011: Eizabeth Long; Donna-Marie McCafferty; Brandie Millen; Heitor A Paula-Neto; Alexander C Klimowicz; Paul Kubes; Stephen M Robbins
A subclass of acylated anti-inflammatory mediators usurp Toll-like receptor 2 to inhibit neutrophil recruitment through peroxisome proliferator-activated receptor gamma.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(39):16357-62.
2011: Erin F McAvoy; Braedon McDonald; Sean A Parsons; Connie H Wong; Regine Landmann; Paul Kubes
The role of CD14 in neutrophil recruitment within the liver microcirculation during endotoxemia.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(4):2592-601.
2011: Björn Petri; Jaswinder Kaur; Elizabeth M Long; Hang Li; Sean A Parsons; Stefan Butz; Mia Phillipson; Dietmar Vestweber; Kamala D Patel; Stephen M Robbins; Paul Kubes
Endothelial LSP1 is involved in endothelial dome formation, minimizing vascular permeability changes during neutrophil transmigration in vivo.
Blood 2011;117(3):942-52.
2011: Mia Phillipson; Paul Kubes
The neutrophil in vascular inflammation.
Nature medicine 2011;17(11):1381-90.
2011: Craig N Jenne; Björn Petri; Connie H Y Wong; Paul Kubes
The use of spinning-disk confocal microscopy for the intravital analysis of platelet dynamics in response to systemic and local inflammation.
PloS one 2011;6(9):e25109.
2011: Heitor A Paula Neto; Paul Kubes
Platelets, endothelium and shear join forces to mislead neutrophils in sepsis.
Critical care (London, England) 2011;15(1):103.
2010: Florian H Pilsczek; Davide Salina; Karen K H Poon; Candace Fahey; Bryan G Yipp; Christopher D Sibley; Stephen M Robbins; Francis H Y Green; Mike G Surette; Motoyuki Sugai; M Gabriela Bowden; Muzaffar Hussain; Kunyan Zhang; Paul Kubes
A novel mechanism of rapid nuclear neutrophil extracellular trap formation in response to Staphylococcus aureus.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(12):7413-25.
2010: Braedon McDonald; Keir Pittman; Gustavo B Menezes; Simon A Hirota; Ingrid Slaba; Christopher C M Waterhouse; Paul L Beck; Daniel A Muruve; Paul Kubes
Intravascular danger signals guide neutrophils to sites of sterile inflammation.
Science (New York, N.Y.) 2010;330(6002):362-6.
2010: Braedon McDonald; Paul Kubes
Chemokines: sirens of neutrophil recruitment-but is it just one song?
Immunity 2010;33(2):148-9.
2010: Spencer Alexander Freeman; Sarah J McLeod; Janet Dukowski; Pamela Austin; Crystal C Y Lee; Brandie Millen-Martin; Paul Kubes; Donna-Marie McCafferty; Michael Robert Gold; Calvin D Roskelley
Preventing the activation or cycling of the Rap1 GTPase alters adhesion and cytoskeletal dynamics and blocks metastatic melanoma cell extravasation into the lungs.
Cancer research 2010;70(11):4590-601.
2010: Mark R Gillrie; Lori Zbytnuik; Erin McAvoy; Roxna Kapadia; Kristine Lee; Christopher C M Waterhouse; Shevaun P Davis; Daniel A Muruve; Paul Kubes; May Ho
Divergent roles of Toll-like receptor 2 in response to lipoteichoic acid and Staphylococcus aureus in vivo.
European journal of immunology 2010;40(6):1639-50.
2010: Meiqing Shi; Shu Shun Li; Chunfu Zheng; Gareth J Jones; Kwang S Kim; Hong Zhou; Paul Kubes; Christopher H Mody
Real-time imaging of trapping and urease-dependent transmigration of Cryptococcus neoformans in mouse brain.
The Journal of clinical investigation 2010;120(5):1683-93.
2010: Connie H Y Wong; bryan heit; Paul Kubes
Molecular regulators of leucocyte chemotaxis during inflammation.
Cardiovascular research 2010;86(2):183-91.
2010: Woo Yong Lee; Tara J Moriarty; Connie H Y Wong; Hong Zhou; Robert M Strieter; Nico van Rooijen; George Chaconas; Paul Kubes
An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells.
Nature immunology 2010;11(4):295-302.
2010: Christopher C M Waterhouse; Steven Johnson; Mia Phillipson; Lori Zbytnuik; Björn Petri; Margaret Kelly; John B Lowe; Paul Kubes
Secretory cell hyperplasia and defects in Notch activity in a mouse model of leukocyte adhesion deficiency type II.
Gastroenterology 2010;138(3):1079-90.e1-5.
2010: Marie-Renée Blanchet; Matthew Gold; Steven Maltby; Jami Bennett; Björn Petri; Paul Kubes; David M Lee; Kelly M McNagny
Loss of CD34 leads to exacerbated autoimmune arthritis through increased vascular permeability.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(3):1292-9.
2009: Gustavo Batista Menezes; Woo Yong Lee; Hong Zhou; Christopher Curtis Matchett Waterhouse; Denise C Cara; Paul Kubes
Selective down-regulation of neutrophil Mac-1 in endotoxemic hepatic microcirculation via IL-10.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(11):7557-68.
2009: Hong Zhou; Graciela Andonegui; Connie H Y Wong; Paul Kubes
Role of endothelial TLR4 for neutrophil recruitment into central nervous system microvessels in systemic inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(8):5244-50.
2009: Graciela Andonegui; Hong Zhou; Daniel C Bullard; Margaret M Kelly; Sarah C Mullaly; Braedon McDonald; Elizabeth M Long; Stephen M Robbins; Paul Kubes
Mice that exclusively express TLR4 on endothelial cells can efficiently clear a lethal systemic Gram-negative bacterial infection.
The Journal of clinical investigation 2009;119(7):1921-30.
2009: Mia Phillipson; bryan heit; Sean A Parsons; Björn Petri; Sarah C Mullaly; Pina Colarusso; R Michael Gower; Graham G Neely; Scott I Simon; Paul Kubes
Vav1 is essential for mechanotactic crawling and migration of neutrophils out of the inflamed microvasculature.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(11):6870-8.
2009: Gustavo B Menezes; Erin F McAvoy; Paul Kubes
Hyaluronan, platelets, and monocytes: a novel pro-inflammatory triad.
The American journal of pathology 2009;174(6):1993-5.
2009: Michael J Hickey; Paul Kubes
Intravascular immunity: the host-pathogen encounter in blood vessels.
Nature reviews. Immunology 2009;9(5):364-75.
2009: Jami L Bennett; Marie-Renée Blanchet; Linlin Zhao; Lori Zbytnuik; Frann Antignano; Matthew Gold; Paul Kubes; Kelly M McNagny
Bone marrow-derived mast cells accumulate in the central nervous system during inflammation but are dispensable for experimental autoimmune encephalomyelitis pathogenesis.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(9):5507-14.
2009: M Figura; Lisa Chilton; Abdelhamid Liacini; M Maric Viskovic; V Phan; Derrice Knight; Timothy Millar; K Patel; Paul Kubes; Wayne R Giles; Lee Anne Tibbles
Blockade of K(ATP) channels reduces endothelial hyperpolarization and leukocyte recruitment upon reperfusion after hypoxia.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2009;9(4):687-96.
2009: David P Stirling; Shuhong Liu; Paul Kubes; V Wee Yong
Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(3):753-64.
2009: Elizabeth M Long; Brandie Millen; Paul Kubes; Stephen M Robbins
Lipoteichoic acid induces unique inflammatory responses when compared to other toll-like receptor 2 ligands.
PloS one 2009;4(5):e5601.
2008: Julie Audoy-Rémus; Jean-François Richard; Denis Soulet; Hong Zhou; Paul Kubes; Luc Vallières
Rod-Shaped monocytes patrol the brain vasculature and give rise to perivascular macrophages under the influence of proinflammatory cytokines and angiopoietin-2.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(41):10187-99.
2008: Katie L Lloyd-Jones; Margaret M Kelly; Paul Kubes
Varying importance of soluble and membrane CD14 in endothelial detection of lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(2):1446-53.
2008: bryan heit; Stephen M Robbins; Charlene M Downey; Zhiwen Guan; Pina Colarusso; B Joan Miller; Frank R Jirik; Paul Kubes
PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils.
Nature immunology 2008;9(7):743-52.
2008: Tara J Moriarty; M Ursula Norman; Pina Colarusso; Troy Bankhead; Paul Kubes; George Chaconas
Real-time high resolution 3D imaging of the lyme disease spirochete adhering to and escaping from the vasculature of a living host.
PLoS pathogens 2008;4(6):e1000090.
2008: Chun Fu Zheng; Gareth J Jones; Meiqing Shi; Jeremy C D Wiseman; Kaleb J Marr; Byron M Berenger; Shaunna M Huston; M John Gill; Alan Krensky; Paul Kubes; Christopher H Mody
Late expression of granulysin by microbicidal CD4+ T cells requires PI3K- and STAT5-dependent expression of IL-2Rbeta that is defective in HIV-infected patients.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(11):7221-9.
2008: M Ursula Norman; John Hwang; Sara Hulliger; Claudine S Bonder; Jun Yamanouchi; Pere Santamaria; Paul Kubes
Mast cells regulate the magnitude and the cytokine microenvironment of the contact hypersensitivity response.
The American journal of pathology 2008;172(6):1638-49.
2008: Björn Petri; Mia Phillipson; Paul Kubes
The physiology of leukocyte recruitment: an in vivo perspective.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(10):6439-46.
2008: M Ursula Norman; Lori Zbytnuik; Paul Kubes
Interferon-gamma limits Th1 lymphocyte adhesion to inflamed endothelium: a nitric oxide regulatory feedback mechanism.
European journal of immunology 2008;38(5):1368-80.
2008: Braedon McDonald; Erin F McAvoy; Florence Lam; Varinder Gill; Carol de la Motte; Rashmin C Savani; Paul Kubes
Interaction of CD44 and hyaluronan is the dominant mechanism for neutrophil sequestration in inflamed liver sinusoids.
The Journal of experimental medicine 2008;205(4):915-27.
2008: Woo Yong Lee; Paul Kubes
Leukocyte adhesion in the liver: distinct adhesion paradigm from other organs.
Journal of hepatology 2008;48(3):504-12.
2008: Steven M Kerfoot; Krista McRae; Florence Lam; Erin F McAvoy; Stephen Clark; Michael Brain; Patricia F Lalor; David H Adams; Paul Kubes
A novel mechanism of erythrocyte capture from circulation in humans.
Experimental hematology 2008;36(2):111-8.
2008: Margaret M Kelly; Kelly McNagny; David L Williams; Nico van Rooijen; Lori Maxwell; Carol Gwozd; Christopher H Mody; Paul Kubes
The lung responds to zymosan in a unique manner independent of toll-like receptors, complement, and dectin-1.
American journal of respiratory cell and molecular biology 2008;38(2):227-38.
2008: bryan heit; Lixin Liu; Pina Colarusso; Kamal D Puri; Paul Kubes
PI3K accelerates, but is not required for, neutrophil chemotaxis to fMLP.
Journal of cell science 2008;121(Pt 2):205-14.
2008: M Ursula Norman; Tara J Moriarty; Ashley R Dresser; Brandie Millen; Paul Kubes; George Chaconas
Molecular mechanisms involved in vascular interactions of the Lyme disease pathogen in a living host.
PLoS pathogens 2008;4(10):e1000169.
2008: Mia Phillipson; Jaswinder Kaur; Pina Colarusso; Christie M Ballantyne; Paul Kubes
Endothelial domes encapsulate adherent neutrophils and minimize increases in vascular permeability in paracellular and transcellular emigration.
PloS one 2008;3(2):e1649.
2008: M Ursula Norman; Sara Hulliger; Pina Colarusso; Paul Kubes
Multichannel fluorescence spinning disk microscopy reveals early endogenous CD4 T cell recruitment in contact sensitivity via complement.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(1):510-21.
2007: Lixin Liu; Kamal D Puri; Josef M Penninger; Paul Kubes
Leukocyte PI3Kgamma and PI3Kdelta have temporally distinct roles for leukocyte recruitment in vivo.
Blood 2007;110(4):1191-8.
2007: Bryan G Yipp; Michael J Hickey; Graciela Andonegui; Allan G Murray; Sornchai Looareesuwan; Paul Kubes; May Ho
Differential roles of CD36, ICAM-1, and P-selectin in Plasmodium falciparum cytoadherence in vivo.
Microcirculation (New York, N.Y. : 1994) 2007;14(6):593-602.
2007: Margaret Kelly; John M Hwang; Paul Kubes
Modulating leukocyte recruitment in inflammation.
The Journal of allergy and clinical immunology 2007;120(1):3-10.
2007: Stephen Clark; Adrienne C Ma; Samantha A Tavener; Braedon McDonald; Zahra Goodarzi; Margaret M Kelly; Kamala D Patel; Subhadeep Chakrabarti; Erin McAvoy; Gary D Sinclair; Elizabeth M Keys; Emma Allen-Vercoe; Rebekah DeVinney; Christopher J Doig; Francis H Y Green; Paul Kubes
Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood.
Nature medicine 2007;13(4):463-9.
2007: Chun Fu Zheng; Ling Ling Ma; Gareth J Jones; M John Gill; Alan Krensky; Paul Kubes; Christopher H Mody
Cytotoxic CD4+ T cells use granulysin to kill Cryptococcus neoformans, and activation of this pathway is defective in HIV patients.
Blood 2007;109(5):2049-57.
2007: Sarah C Mullaly; Paul Kubes
Mast cell-expressed complement receptor, not TLR2, is the main detector of zymosan in peritonitis.
European journal of immunology 2007;37(1):224-34.
2006: Sarah C Mullaly; Paul Kubes
The role of TLR2 in vivo following challenge with Staphylococcus aureus and prototypic ligands.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(11):8154-63.
2006: Hong Zhou; Benoît M Lapointe; Stephen Clark; Lori Zbytnuik; Paul Kubes
A requirement for microglial TLR4 in leukocyte recruitment into brain in response to lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(11):8103-10.
2006: Mia Phillipson; bryan heit; Pina Colarusso; Lixin Liu; Christie M Ballantyne; Paul Kubes
Intraluminal crawling of neutrophils to emigration sites: a molecularly distinct process from adhesion in the recruitment cascade.
The Journal of experimental medicine 2006;203(12):2569-75.
2006: Erin F McAvoy; Paul Kubes
Holey endothelium: gateways for naïve T cell activation.
Hepatology (Baltimore, Md.) 2006;44(5):1083-5.
2006: bryan heit; Gareth Jones; Derrice Knight; JOSEPH ANTONY; M John Gill; Christopher Brown; Christopher Power; Paul Kubes
HIV and other lentiviral infections cause defects in neutrophil chemotaxis, recruitment, and cell structure: immunorestorative effects of granulocyte-macrophage colony-stimulating factor.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(9):6405-14.
2006: Katie L Lloyd; Paul Kubes
GPI-linked endothelial CD14 contributes to the detection of LPS.
American journal of physiology. Heart and circulatory physiology 2006;291(1):H473-81.
2006: Claudine S Bonder; Stephen Clark; M Ursula Norman; Pauline Johnson; Paul Kubes
Use of CD44 by CD4+ Th1 and Th2 lymphocytes to roll and adhere.
Blood 2006;107(12):4798-806.
2006: Steven M Kerfoot; M Ursula Norman; Benoît M Lapointe; Claudine S Bonder; Lori Zbytnuik; Paul Kubes
Reevaluation of P-selectin and alpha 4 integrin as targets for the treatment of experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(10):6225-34.
2006: Samantha A Tavener; Paul Kubes
Cellular and molecular mechanisms underlying LPS-associated myocyte impairment.
American journal of physiology. Heart and circulatory physiology 2006;290(2):H800-6.
2006: Steven M Kerfoot; Charlotte D'Mello; Henry Nguyen; Maureen N Ajuebor; Paul Kubes; Tai Le; Mark G Swain
TNF-alpha-secreting monocytes are recruited into the brain of cholestatic mice.
Hepatology (Baltimore, Md.) 2006;43(1):154-62.
2005: Paul R Mangan; Darrell O'Quinn; Laurie Harrington; Claudine S Bonder; Paul Kubes; Dennis F Kucik; Daniel C Bullard; Casey T Weaver
Both Th1 and Th2 cells require P-selectin glycoprotein ligand-1 for optimal rolling on inflamed endothelium.
The American journal of pathology 2005;167(6):1661-75.
2005: Claudine S Bonder; M Ursula Norman; Tara Macrae; Paul R Mangan; Casey T Weaver; Daniel C Bullard; Donna-Marie McCafferty; Paul Kubes
P-selectin can support both Th1 and Th2 lymphocyte rolling in the intestinal microvasculature.
The American journal of pathology 2005;167(6):1647-60.
2005: bryan heit; Pina Colarusso; Paul Kubes
Fundamentally different roles for LFA-1, Mac-1 and alpha4-integrin in neutrophil chemotaxis.
Journal of cell science 2005;118(Pt 22):5205-20.
2005: Graciela Andonegui; Steven M Kerfoot; Kelly M McNagny; Kirsten V J Ebbert; Kamala D Patel; Paul Kubes
Platelets express functional Toll-like receptor-4.
Blood 2005;106(7):2417-23.
2005: Varinder Gill; Christopher J Doig; Derrice Knight; Emma Love; Paul Kubes
Targeting adhesion molecules as a potential mechanism of action for intravenous immunoglobulin.
Circulation 2005;112(13):2031-9.
2005: Claudine S Bonder; M Ursula Norman; Mark G Swain; Lori Zbytnuik; Jun Yamanouchi; Pere Santamaria; Maureen N Ajuebor; Marko Salmi; Sirpa Jalkanen; Paul Kubes
Rules of recruitment for Th1 and Th2 lymphocytes in inflamed liver: a role for alpha-4 integrin and vascular adhesion protein-1.
Immunity 2005;23(2):153-63.
2005: Samantha A Tavener; Paul Kubes
Is there a role for cardiomyocyte toll-like receptor 4 in endotoxemia?
Trends in cardiovascular medicine 2005;15(5):153-7.
2005: Adil I Khan; bryan heit; Graciela Andonegui; Pina Colarusso; Paul Kubes
Lipopolysaccharide: a p38 MAPK-dependent disrupter of neutrophil chemotaxis.
Microcirculation (New York, N.Y. : 1994) 2005;12(5):421-32.
2005: Steven M Kerfoot; Paul Kubes
Local coordination verses systemic disregulation: complexities in leukocyte recruitment revealed by local and systemic activation of TLR4 in vivo.
Journal of leukocyte biology 2005;77(6):862-7.
2005: Lixin Liu; Denise C Cara; Jaswinder Kaur; Eko Raharjo; Sarah C Mullaly; Jenny Jongstra-Bilen; Jan Jongstra; Paul Kubes
LSP1 is an endothelial gatekeeper of leukocyte transendothelial migration.
The Journal of experimental medicine 2005;201(3):409-18.
2005: M Ursula Norman; Paul Kubes
Therapeutic intervention in inflammatory diseases: a time and place for anti-adhesion therapy.
Microcirculation (New York, N.Y. : 1994) 2005;12(1):91-8.
2004: Adil I Khan; Steven M Kerfoot; bryan heit; Lixin Liu; Graciela Andonegui; Brian Ruffell; Pauline Johnson; Paul Kubes
Role of CD44 and hyaluronan in neutrophil recruitment.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(12):7594-601.
2004: Steven M Kerfoot; Eizabeth Long; Michael J Hickey; Graciela Andonegui; Benoît M Lapointe; Renata C O Zanardo; Claudine S Bonder; Will G James; Stephen M Robbins; Paul Kubes
TLR4 contributes to disease-inducing mechanisms resulting in central nervous system autoimmune disease.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(11):7070-7.
2004: Benoît M Lapointe; Leonie M Herx; Varinder Gill; Luanne M Metz; Paul Kubes
IVIg therapy in brain inflammation: etiology-dependent differential effects on leucocyte recruitment.
Brain : a journal of neurology 2004;127(Pt 12):2649-56.
2004: Renata C O Zanardo; Claudine S Bonder; John M Hwang; Graciela Andonegui; Lixin Liu; Dietmar Vestweber; Lori Zbytnuik; Paul Kubes
A down-regulatable E-selectin ligand is functionally important for PSGL-1-independent leukocyte-endothelial cell interactions.
Blood 2004;104(12):3766-73.
2004: Sarah C Mullaly; Paul Kubes
Toll gates and traffic arteries: from endothelial TLR2 to atherosclerosis.
Circulation research 2004;95(7):657-9.
2004: Samantha A Tavener; Eizabeth Long; Stephen M Robbins; Krista M McRae; Holly Van Remmen; Paul Kubes
Immune cell Toll-like receptor 4 is required for cardiac myocyte impairment during endotoxemia.
Circulation research 2004;95(7):700-7.
2004: Claudine S Bonder; Derrice Knight; Daniel Hernandez-Saavedra; Joe M McCord; Paul Kubes
Chimeric SOD2/3 inhibits at the endothelial-neutrophil interface to limit vascular dysfunction in ischemia-reperfusion.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(3):G676-84.
2004: Slava Epelman; Danuta Stack; Chris Bell; Erica Wong; Graham G Neely; Stephan R Krutzik; Kensuke Miyake; Paul Kubes; Lori Zbytnuik; Ling Ling Ma; Xiaobin Xie; Donald E Woods; Christopher H Mody
Different domains of Pseudomonas aeruginosa exoenzyme S activate distinct TLRs.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(3):2031-40.
2004: John M Hwang; Jun Yamanouchi; Pere Santamaria; Paul Kubes
A critical temporal window for selectin-dependent CD4+ lymphocyte homing and initiation of late-phase inflammation in contact sensitivity.
The Journal of experimental medicine 2004;199(9):1223-34.
2004: Ella S M Ng; David Jourd'heuil; Joe M McCord; Daniel Hernandez; Mitsukuni Yasui; Derrice Knight; Paul Kubes
Enhanced S-nitroso-albumin formation from inhaled NO during ischemia/reperfusion.
Circulation research 2004;94(4):559-65.
2004: Claudine S Bonder; Maureen N Ajuebor; Lori Zbytnuik; Paul Kubes; Mark G Swain
Essential role for neutrophil recruitment to the liver in concanavalin A-induced hepatitis.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(1):45-53.
2004: Denise C Cara; Paul Kubes
Intravital microscopy as a tool for studying recruitment and chemotaxis.
Methods in molecular biology (Clifton, N.J.) 2004;239():123-32.
2003: Guglielmo M Venturi; LiLi Tu; Takafumi Kadono; Adil I Khan; Yoko Fujimoto; Philip Oshel; Cheryl B Bock; Ann S Miller; Ralph M Albrecht; Paul Kubes; Douglas A Steeber; Thomas F Tedder
Leukocyte migration is regulated by L-selectin endoproteolytic release.
Immunity 2003;19(5):713-24.
2003: Paul Kubes; bryan heit; Guido Van Marle; James B Johnston; Derrice Knight; Adil Khan; Christopher Power
In vivo impairment of neutrophil recruitment during lentivirus infection.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(9):4801-8.
2003: Betty Y Poon; Eko Raharjo; Kamala D Patel; Samantha A Tavener; Paul Kubes
Complexity of inducible nitric oxide synthase: cellular source determines benefit versus toxicity.
Circulation 2003;108(9):1107-12.
2003: Ella S M Ng; Paul Kubes
The physiology of S-nitrosothiols: carrier molecules for nitric oxide.
Canadian journal of physiology and pharmacology 2003;81(8):759-64.
2003: Adil I Khan; Paul Kubes
L-selectin: an emerging player in chemokine function.
Microcirculation (New York, N.Y. : 1994) 2003;10(3-4):351-8.
2003: Supattra Serirom; Wahaju H Raharjo; Kesinee Chotivanich; Sornchai Loareesuwan; Paul Kubes; May Ho
Anti-adhesive effect of nitric oxide on Plasmodium falciparum cytoadherence under flow.
The American journal of pathology 2003;162(5):1651-60.
2003: Claudine S Bonder; Paul Kubes
The future of GI and liver research: editorial perspectives: II. Modulating leukocyte recruitment to splanchnic organs to reduce inflammation.
American journal of physiology. Gastrointestinal and liver physiology 2003;284(5):G729-33.
2003: Graciela Andonegui; Claudine S Bonder; Francis Green; Sarah C Mullaly; Lori Zbytnuik; Eko Raharjo; Paul Kubes
Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs.
The Journal of clinical investigation 2003;111(7):1011-20.
2003: Jaswinder Kaur; Richard C Woodman; Paul Kubes
P38 MAPK: critical molecule in thrombin-induced NF-kappa B-dependent leukocyte recruitment.
American journal of physiology. Heart and circulatory physiology 2003;284(4):H1095-103.
2003: Steven M Kerfoot; Sarah E Lord; Robert B Bell; Varinder Gill; Stephen M Robbins; Paul Kubes
Human fractalkine mediates leukocyte adhesion but not capture under physiological shear conditions; a mechanism for selective monocyte recruitment.
European journal of immunology 2003;33(3):729-39.
2003: bryan heit; Paul Kubes
Measuring chemotaxis and chemokinesis: the under-agarose cell migration assay.
Science's STKE : signal transduction knowledge environment 2003;2003(170):PL5.
2003: Lixin Liu; Paul Kubes
Molecular mechanisms of leukocyte recruitment: organ-specific mechanisms of action.
Thrombosis and haemostasis 2003;89(2):213-20.
2003: Bryan G Yipp; Dror I Baruch; Ciaran Brady; Allan G Murray; Sornchai Looareesuwan; Paul Kubes; May Ho
Recombinant PfEMP1 peptide inhibits and reverses cytoadherence of clinical Plasmodium falciparum isolates in vivo.
Blood 2003;101(1):331-7.
2002: Yang Li; Daniel A Muruve; Robert G Collins; Samuel S Lee; Paul Kubes
The role of selectins and integrins in adenovirus vector-induced neutrophil recruitment to the liver.
European journal of immunology 2002;32(12):3443-52.
2002: bryan heit; Samantha A Tavener; Eko Raharjo; Paul Kubes
An intracellular signaling hierarchy determines direction of migration in opposing chemotactic gradients.
The Journal of cell biology 2002;159(1):91-102.
2002: Graciela Andonegui; Sanna Goyert; Paul Kubes
Lipopolysaccharide-induced leukocyte-endothelial cell interactions: a role for CD14 versus toll-like receptor 4 within microvessels.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(4):2111-9.
2002: Steven M Kerfoot; Paul Kubes
Overlapping roles of P-selectin and alpha 4 integrin to recruit leukocytes to the central nervous system in experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(2):1000-6.
2002: John Wong; Paul Kubes; Yikun Zhang; Yang Li; Stefan J Urbanski; C Frank Bennett; Samuel S Lee
Role of ICAM-1 in chronic hepatic allograft rejection in the rat.
American journal of physiology. Gastrointestinal and liver physiology 2002;283(1):G196-203.
2002: Paul Kubes; Derrice Payne; Richard C Woodman
Molecular mechanisms of leukocyte recruitment in postischemic liver microcirculation.
American journal of physiology. Gastrointestinal and liver physiology 2002;283(1):G139-47.
2002: Michael J Hickey; Elaine Sihota; Abdelaziz Amrani; Pere Santamaria; Lori Zbytnuik; Ella S M Ng; Winnie Ho; Keith Sharkey; Paul Kubes
Inducible nitric oxide synthase (iNOS) in endotoxemia: chimeric mice reveal different cellular sources in various tissues.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(9):1141-3.
2002: Bryan G Yipp; Graciela Andonegui; Christopher J Howlett; Stephen M Robbins; Thomas Hartung; May Ho; Paul Kubes
Profound differences in leukocyte-endothelial cell responses to lipopolysaccharide versus lipoteichoic acid.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4650-8.
2002: Paul Kubes
The complexities of leukocyte recruitment.
Seminars in immunology 2002;14(2):65-72.
2002: Tailoi Chan-Ling; Mary E Gerritsen; Caryl E Hill; Paul Kubes; Michael Perry
Microcirculation down under.
Trends in pharmacological sciences 2002;23(3):106-8.
2001: Denise C Cara; Jaswinder Kaur; M Forster; Donna-Marie McCafferty; Paul Kubes
Role of p38 mitogen-activated protein kinase in chemokine-induced emigration and chemotaxis in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(11):6552-8.
2001: Steven M Kerfoot; Eko Raharjo; May Ho; Jaswinder Kaur; S Serirom; Donna-Marie McCafferty; A R Burns; Kamala D Patel; Paul Kubes
Exclusive neutrophil recruitment with oncostatin M in a human system.
The American journal of pathology 2001;159(4):1531-9.
2001: M J Sanz; Michael J Hickey; B Johnston; Donna-Marie McCafferty; Eko Raharjo; P L Huang; Paul Kubes
Neuronal nitric oxide synthase (NOS) regulates leukocyte-endothelial cell interactions in endothelial NOS deficient mice.
British journal of pharmacology 2001;134(2):305-12.
2001: Jaswinder Kaur; Richard C Woodman; L Ostrovsky; Paul Kubes
Selective recruitment of neutrophils and lymphocytes by thrombin: a role for NF-kappaB.
American journal of physiology. Heart and circulatory physiology 2001;281(2):H784-95.
2001: Paul Kubes; Steven M Kerfoot
Leukocyte recruitment in the microcirculation: the rolling paradigm revisited.
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society 2001;16():76-80.
2001: G C Ibbotson; Christopher J Doig; Jaswinder Kaur; Varinder Gill; L Ostrovsky; T Fairhead; Paul Kubes
Functional alpha4-integrin: a newly identified pathway of neutrophil recruitment in critically ill septic patients.
Nature medicine 2001;7(4):465-70.
2001: Betty Y Poon; Christopher A Ward; Conan B Cooper; Wayne R Giles; A R Burns; Paul Kubes
alpha(4)-integrin mediates neutrophil-induced free radical injury to cardiac myocytes.
The Journal of cell biology 2001;152(5):857-66.
2000: Michael J Hickey; M Forster; D Mitchell; Jaswinder Kaur; C De Caigny; Paul Kubes
L-selectin facilitates emigration and extravascular locomotion of leukocytes during acute inflammatory responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(12):7164-70.
2000: J Carvalho-Tavares; Michael J Hickey; J Hutchison; J Michaud; I T Sutcliffe; Paul Kubes
A role for platelets and endothelial selectins in tumor necrosis factor-alpha-induced leukocyte recruitment in the brain microvasculature.
Circulation research 2000;87(12):1141-8.
2000: May Ho; Michael J Hickey; Allan G Murray; Graciela Andonegui; Paul Kubes
Visualization of Plasmodium falciparum-endothelium interactions in human microvasculature: mimicry of leukocyte recruitment.
The Journal of experimental medicine 2000;192(8):1205-11.
2000: Richard C Woodman; Desiree A Teoh; Derrice Payne; Paul Kubes
Thrombin and leukocyte recruitment in endotoxemia.
American journal of physiology. Heart and circulatory physiology 2000;279(3):H1338-45.
2000: Donna-Marie McCafferty; S Kanwar; DN Granger; Paul Kubes
E/P-selectin-deficient mice: an optimal mutation for abrogating antigen but not tumor necrosis factor-alpha-induced immune responses.
European journal of immunology 2000;30(8):2362-71.
2000: Donna-Marie McCafferty; Elaine Sihota; Marcelo N Muscara; John L Wallace; Keith Sharkey; Paul Kubes
Spontaneously developing chronic colitis in IL-10/iNOS double-deficient mice.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(1):G90-9.
2000: Paul Kubes
Inducible nitric oxide synthase: a little bit of good in all of us.
Gut 2000;47(1):6-9.
2000: AE Fox-Robichaud; Paul Kubes
Molecular mechanisms of tumor necrosis factor alpha-stimulated leukocyte recruitment into the murine hepatic circulation.
Hepatology (Baltimore, Md.) 2000;31(5):1123-7.
2000: D J Mitchell; P Li; PH Reinhardt; Paul Kubes
Importance of L-selectin-dependent leukocyte-leukocyte interactions in human whole blood.
Blood 2000;95(9):2954-9.
2000: B Johnston; A R Burns; M Suematsu; K Watanabe; Thomas B Issekutz; Paul Kubes
Increased sensitivity to the C-X-C chemokine CINC/gro in a model of chronic inflammation.
Microcirculation (New York, N.Y. : 1994) 2000;7(2):109-18.
2000: L Ostrovsky; J Carvalho-Tavares; Richard C Woodman; Paul Kubes
Translational inhibition of E-selectin expression stimulates P-selectin-dependent neutrophil recruitment.
American journal of physiology. Heart and circulatory physiology 2000;278(4):H1225-32.
2000: B Johnston; A Chee; Thomas B Issekutz; T Ugarova; AE Fox-Robichaud; Michael J Hickey; Paul Kubes
Alpha 4 integrin-dependent leukocyte recruitment does not require VCAM-1 in a chronic model of inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(6):3337-44.
2000: Hong Ding; Paul Kubes; Chris R Triggle
Potassium- and acetylcholine-induced vasorelaxation in mice lacking endothelial nitric oxide synthase.
British journal of pharmacology 2000;129(6):1194-200.
1999: AE Fox-Robichaud; Derrice Payne; Paul Kubes
Inhaled NO reaches distal vasculatures to inhibit endothelium- but not leukocyte-dependent cell adhesion.
The American journal of physiology 1999;277(6 Pt 1):L1224-31.
1999: B Johnston; Paul Kubes
The alpha4-integrin: an alternative pathway for neutrophil recruitment?
Immunology today 1999;20(12):545-50.
1999: Donna-Marie McCafferty; Marcel Miampamba; Elaine Sihota; Keith Sharkey; Paul Kubes
Role of inducible nitric oxide synthase in trinitrobenzene sulphonic acid induced colitis in mice.
Gut 1999;45(6):864-73.
1999: M J Sanz; B Johnston; A Issekutz; Paul Kubes
Endothelin-1 causes P-selectin-dependent leukocyte rolling and adhesion within rat mesenteric microvessels.
The American journal of physiology 1999;277(5 Pt 2):H1823-30.
1999: Gareth Waldron; Hong Ding; Fina Lovren; Paul Kubes; Chris R Triggle
Acetylcholine-induced relaxation of peripheral arteries isolated from mice lacking endothelial nitric oxide synthase.
British journal of pharmacology 1999;128(3):653-8.
1999: Michael J Hickey; DN Granger; Paul Kubes
Molecular mechanisms underlying IL-4-induced leukocyte recruitment in vivo: a critical role for the alpha 4 integrin.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(6):3441-8.
1999: Paul Kubes; Derrice Payne; M B Grisham; D Jourd-Heuil; AE Fox-Robichaud
Inhaled NO impacts vascular but not extravascular compartments in postischemic peripheral organs.
The American journal of physiology 1999;277(2 Pt 2):H676-82.
1999: Donna-Marie McCafferty; CW Smith; DN Granger; Paul Kubes
Intestinal inflammation in adhesion molecule-deficient mice: an assessment of P-selectin alone and in combination with ICAM-1 or E-selectin.
Journal of leukocyte biology 1999;66(1):67-74.
1999: Betty Y Poon; Christopher A Ward; Wayne R Giles; Paul Kubes
Emigrated neutrophils regulate ventricular contractility via alpha4 integrin.
Circulation research 1999;84(11):1245-51.
1999: B Johnston; J P Gaboury; M Suematsu; Paul Kubes
Nitric oxide inhibits microvascular protein leakage induced by leukocyte adhesion-independent and adhesion-dependent inflammatory mediators.
Microcirculation (New York, N.Y. : 1994) 1999;6(2):153-62.
1999: B Johnston; A R Burns; M Suematsu; Thomas B Issekutz; R C Woodman; Paul Kubes
Chronic inflammation upregulates chemokine receptors and induces neutrophil migration to monocyte chemoattractant protein-1.
The Journal of clinical investigation 1999;103(9):1269-76.
1999: J Carvalho-Tavares; AE Fox-Robichaud; Paul Kubes
Assessment of the mechanism of juxtacrine activation and adhesion of leukocytes in liver microcirculation.
The American journal of physiology 1999;276(4 Pt 1):G828-34.
1999: S Kanwar; D A Steeber; T F Tedder; Michael J Hickey; Paul Kubes
Overlapping roles for L-selectin and P-selectin in antigen-induced immune responses in the microvasculature.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(5):2709-16.
1999: Michael J Hickey; S Kanwar; Donna-Marie McCafferty; DN Granger; M J Eppihimer; Paul Kubes
Varying roles of E-selectin and P-selectin in different microvascular beds in response to antigen.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(2):1137-43.
1999: Paul Kubes
Ruthenium red as measure of mast cell activation.
Methods in enzymology 1999;301():22-7.
1998: PH Reinhardt; Paul Kubes
Differential leukocyte recruitment from whole blood via endothelial adhesion molecules under shear conditions.
Blood 1998;92(12):4691-9.
1998: Richard C Woodman; B Johnston; Michael J Hickey; Desiree A Teoh; PH Reinhardt; Betty Y Poon; Paul Kubes
The functional paradox of CD43 in leukocyte recruitment: a study using CD43-deficient mice.
The Journal of experimental medicine 1998;188(11):2181-6.
1998: Michael J Hickey; Andrew C Issekutz; PH Reinhardt; R N Fedorak; Paul Kubes
Endogenous interleukin-10 regulates hemodynamic parameters, leukocyte-endothelial cell interactions, and microvascular permeability during endotoxemia.
Circulation research 1998;83(11):1124-31.
1998: S Kanwar; Michael J Hickey; Paul Kubes
Postischemic inflammation: a role for mast cells in intestine but not in skeletal muscle.
The American journal of physiology 1998;275(2 Pt 1):G212-8.
1998: G D Withers; Paul Kubes; G Ibbotson; R Brent Scott
Anaphylaxis-induced mesenteric vascular permeability, granulocyte adhesion, and platelet aggregates in rat.
The American journal of physiology 1998;275(1 Pt 2):H274-84.
1998: May Ho; T Schollaardt; X Niu; Sornchai Looareesuwan; Kamala D Patel; Paul Kubes
Characterization of Plasmodium falciparum-infected erythrocyte and P-selectin interaction under flow conditions.
Blood 1998;91(12):4803-9.
1998: AE Fox-Robichaud; Derrice Payne; Shabih U Hasan; L Ostrovsky; T Fairhead; PH Reinhardt; Paul Kubes
Inhaled NO as a viable antiadhesive therapy for ischemia/reperfusion injury of distal microvascular beds.
The Journal of clinical investigation 1998;101(11):2497-505.
1998: L Ostrovsky; A J King; S Bond; D Mitchell; DE Lorant; Guy A Zimmerman; R Larsen; X F Niu; Paul Kubes
A juxtacrine mechanism for neutrophil adhesion on platelets involves platelet-activating factor and a selectin-dependent activation process.
Blood 1998;91(8):3028-36.
1998: Richard C Woodman; L Ostrovsky; Desiree A Teoh; Derrice Payne; Man-Chiu Poon; Paul Kubes
Antithrombin and ischemia/reperfusion.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1998;9 Suppl 2():S7-15.
1998: Paul Kubes; Derrice Payne; L Ostrovsky
Preconditioning and adenosine in I/R-induced leukocyte-endothelial cell interactions.
The American journal of physiology 1998;274(4 Pt 2):H1230-8.
1998: B Johnston; A R Burns; Paul Kubes
A role for mast cells in the development of adjuvant-induced vasculitis and arthritis.
The American journal of pathology 1998;152(2):555-63.
1998: S Kanwar; CW Smith; Paul Kubes
An absolute requirement for P-selectin in ischemia/reperfusion-induced leukocyte recruitment in cremaster muscle.
Microcirculation (New York, N.Y. : 1994) 1998;5(4):281-7.
1997: B Johnston; U M Walter; Andrew C Issekutz; Thomas B Issekutz; D C Anderson; Paul Kubes
Differential roles of selectins and the alpha4-integrin in acute, subacute, and chronic leukocyte recruitment in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(9):4514-23.
1997: L Ostrovsky; Richard C Woodman; Derrice Payne; Desiree A Teoh; Paul Kubes
Antithrombin III prevents and rapidly reverses leukocyte recruitment in ischemia/reperfusion.
Circulation 1997;96(7):2302-10.
1997: Michael J Hickey; Keith Sharkey; Elaine Sihota; PH Reinhardt; JD MacMicking; C Nathan; Paul Kubes
Inducible nitric oxide synthase-deficient mice have enhanced leukocyte-endothelium interactions in endotoxemia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1997;11(12):955-64.
1997: Paul Kubes
The role of shear forces in ischemia/reperfusion-induced neutrophil rolling and adhesion.
Journal of leukocyte biology 1997;62(4):458-64.
1997: Paul Kubes; Elaine Sihota; Michael J Hickey
Endogenous but not exogenous nitric oxide decreases TNF-alpha-induced leukocyte rolling.
The American journal of physiology 1997;273(3 Pt 1):G628-35.
1997: Samuel A Zamora; Harish J Amin; Douglas D McMillan; Paul Kubes; Gordon H Fick; J D Bützner; Howard G Parsons; R Brent Scott
Plasma L-arginine concentrations in premature infants with necrotizing enterocolitis.
The Journal of pediatrics 1997;131(2):226-32.
1997: PH Reinhardt; Christopher A Ward; Wayne R Giles; Paul Kubes
Emigrated rat neutrophils adhere to cardiac myocytes via alpha 4 integrin.
Circulation research 1997;81(2):196-201.
1997: J Wong; B Johnston; Samuel S Lee; Daniel C Bullard; C W Smith; Arthur L Beaudet; Paul Kubes
A minimal role for selectins in the recruitment of leukocytes into the inflamed liver microvasculature.
The Journal of clinical investigation 1997;99(11):2782-90.
1997: PH Reinhardt; John Elliott; Paul Kubes
Neutrophils can adhere via alpha4beta1-integrin under flow conditions.
Blood 1997;89(10):3837-46.
1997: R Udomsangpetch; PH Reinhardt; T Schollaardt; John Elliott; Paul Kubes; May Ho
Promiscuity of clinical Plasmodium falciparum isolates for multiple adhesion molecules under flow conditions.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(9):4358-64.
1997: Michael J Hickey; PH Reinhardt; L Ostrovsky; W M Jones; Mark A Jutila; Derrice Payne; J Elliott; Paul Kubes
Tumor necrosis factor-alpha induces leukocyte recruitment by different mechanisms in vivo and in vitro.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(7):3391-400.
1997: S Kanwar; Daniel C Bullard; Michael J Hickey; CW Smith; Arthur L Beaudet; B A Wolitzky; Paul Kubes
The association between alpha4-integrin, P-selectin, and E-selectin in an allergic model of inflammation.
The Journal of experimental medicine 1997;185(6):1077-87.
1997: Donna-Marie McCafferty; J S Mudgett; Mark G Swain; Paul Kubes
Inducible nitric oxide synthase plays a critical role in resolving intestinal inflammation.
Gastroenterology 1997;112(3):1022-7.
1996: Paul Kubes; J P Gaboury
Rapid mast cell activation causes leukocyte-dependent and -independent permeability alterations.
The American journal of physiology 1996;271(6 Pt 2):H2438-46.
1996: X F Niu; G Ibbotson; Paul Kubes
A balance between nitric oxide and oxidants regulates mast cell-dependent neutrophil-endothelial cell interactions.
Circulation research 1996;79(5):992-9.
1996: Paul Kubes; D N Granger
Leukocyte-endothelial cell interactions evoked by mast cells.
Cardiovascular research 1996;32(4):699-708.
1996: B Johnston; S Kanwar; Paul Kubes
Hydrogen peroxide induces leukocyte rolling: modulation by endogenous antioxidant mechanisms including NO.
The American journal of physiology 1996;271(2 Pt 2):H614-21.
1996: S Kanwar; Paul Kubes; B L Tepperman; Samuel S Lee
Nitric oxide synthase activity in portal-hypertensive and cirrhotic rats.
Journal of hepatology 1996;25(1):85-9.
1996: K Tjandra; Paul Kubes; K Rioux; Mark G Swain
Endogenous glucocorticoids inhibit neutrophil recruitment to inflammatory sites in cholestatic rats.
The American journal of physiology 1996;270(5 Pt 1):G821-5.
1996: B Johnston; Thomas B Issekutz; Paul Kubes
The alpha 4-integrin supports leukocyte rolling and adhesion in chronically inflamed postcapillary venules in vivo.
The Journal of experimental medicine 1996;183(5):1995-2006.
1996: I Alican; Paul Kubes
A critical role for nitric oxide in intestinal barrier function and dysfunction.
The American journal of physiology 1996;270(2 Pt 1):G225-37.
1996: J P Gaboury; X F Niu; Paul Kubes
Nitric oxide inhibits numerous features of mast cell-induced inflammation.
Circulation 1996;93(2):318-26.
1996: D Neil Granger; Paul Kubes
Nitric oxide as antiinflammatory agent.
Methods in enzymology 1996;269():434-42.
1996: PH Reinhardt; Paul H Naccache; Patrice E Poubelle; R de Médicis; M E Kehrli; Paul Kubes
Monosodium urate crystals promote neutrophil adhesion via a CD18-independent and selectin-independent mechanism.
The American journal of physiology 1996;270(1 Pt 1):C31-9.
1995: S Kanwar; B Johnston; Paul Kubes
Leukotriene C4/D4 induces P-selectin and sialyl Lewis(x)-dependent alterations in leukocyte kinetics in vivo.
Circulation research 1995;77(5):879-87.
1995: S Kanwar; Richard C Woodman; Man-Chiu Poon; T Murohara; A M Lefer; K L Davenpeck; Paul Kubes
Desmopressin induces endothelial P-selectin expression and leukocyte rolling in postcapillary venules.
Blood 1995;86(7):2760-6.
1995: Paul Kubes
Nitric oxide affects microvascular permeability in the intact and inflamed vasculature.
Microcirculation (New York, N.Y. : 1994) 1995;2(3):235-44.
1995: Mark G Swain; K Tjandra; S Kanwar; Paul Kubes
Neutrophil adhesion is impaired in rat model of cholestasis.
Gastroenterology 1995;109(3):923-32.
1995: Paul Kubes; X F Niu; C W Smith; M E Kehrli; PH Reinhardt; Richard C Woodman
A novel beta 1-dependent adhesion pathway on neutrophils: a mechanism invoked by dihydrocytochalasin B or endothelial transmigration.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(11):1103-11.
1995: Paul Kubes; PH Reinhardt; Derrice Payne; Richard C Woodman
Excess nitric oxide does not cause cellular, vascular, or mucosal dysfunction in the cat small intestine.
The American journal of physiology 1995;269(1 Pt 1):G34-41.
1995: Paul Kubes; Mark A Jutila; Derrice Payne
Therapeutic potential of inhibiting leukocyte rolling in ischemia/reperfusion.
The Journal of clinical investigation 1995;95(6):2510-9.
1995: S Kanwar; Paul Kubes
Nitric oxide is an antiadhesive molecule for leukocytes.
New horizons (Baltimore, Md.) 1995;3(1):93-104.
1995: J P Gaboury; B Johnston; X F Niu; Paul Kubes
Mechanisms underlying acute mast cell-induced leukocyte rolling and adhesion in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(2):804-13.
1994: S Kanwar; Paul Kubes
Ischemia/reperfusion-induced granulocyte influx is a multistep process mediated by mast cells.
Microcirculation (New York, N.Y. : 1994) 1994;1(3):175-82.
1994: Paul Kubes; I Kurose; D Neil Granger
NO donors prevent integrin-induced leukocyte adhesion but not P-selectin-dependent rolling in postischemic venules.
The American journal of physiology 1994;267(3 Pt 2):H931-7.
1994: S Kanwar; Paul Kubes
Mast cells contribute to ischemia-reperfusion-induced granulocyte infiltration and intestinal dysfunction.
The American journal of physiology 1994;267(2 Pt 1):G316-21.
1994: X F Niu; C W Smith; Paul Kubes
Intracellular oxidative stress induced by nitric oxide synthesis inhibition increases endothelial cell adhesion to neutrophils.
Circulation research 1994;74(6):1133-40.
1994: Paul Kubes; S Kanwar
Histamine induces leukocyte rolling in post-capillary venules. A P-selectin-mediated event.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(7):3570-7.
1994: S Kanwar; B L Tepperman; Derrice Payne; L R Sutherland; Paul Kubes
Time course of nitric oxide production and epithelial dysfunction during ischemia/reperfusion of the feline small intestine.
Circulatory shock 1994;42(3):135-40.
1994: S Kanwar; John L Wallace; D Befus; Paul Kubes
Nitric oxide synthesis inhibition increases epithelial permeability via mast cells.
The American journal of physiology 1994;266(2 Pt 1):G222-9.
1994: J P Gaboury; D C Anderson; Paul Kubes
Molecular mechanisms involved in superoxide-induced leukocyte-endothelial cell interactions in vivo.
The American journal of physiology 1994;266(2 Pt 2):H637-42.
1994: J P Gaboury; Paul Kubes
Reductions in physiologic shear rates lead to CD11/CD18-dependent, selectin-independent leukocyte rolling in vivo.
Blood 1994;83(2):345-50.
1993: Paul Kubes
Nitric oxide-induced microvascular permeability alterations: a regulatory role for cGMP.
The American journal of physiology 1993;265(6 Pt 2):H1909-15.
1993: John L Wallace; Webb McKnight; M Miyasaka; T Tamatani; J Paulson; D C Anderson; DN Granger; Paul Kubes
Role of endothelial adhesion molecules in NSAID-induced gastric mucosal injury.
The American journal of physiology 1993;265(5 Pt 1):G993-8.
1993: Paul Kubes; S Kanwar; X F Niu; J P Gaboury
Nitric oxide synthesis inhibition induces leukocyte adhesion via superoxide and mast cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1993;7(13):1293-9.
1993: Richard C Woodman; PH Reinhardt; S Kanwar; F L Johnston; Paul Kubes
Effects of human neutrophil elastase (HNE) on neutrophil function in vitro and in inflamed microvessels.
Blood 1993;82(7):2188-95.
1993: J Gaboury; Richard C Woodman; DN Granger; PH Reinhardt; Paul Kubes
Nitric oxide prevents leukocyte adherence: role of superoxide.
The American journal of physiology 1993;265(3 Pt 2):H862-7.
1993: Derrice Payne; Paul Kubes
Nitric oxide donors reduce the rise in reperfusion-induced intestinal mucosal permeability.
The American journal of physiology 1993;265(1 Pt 1):G189-95.
1993: I Kurose; Paul Kubes; R Wolf; DC Anderson; J Paulson; M Miyasaka; D Neil Granger
Inhibition of nitric oxide production. Mechanisms of vascular albumin leakage.
Circulation research 1993;73(1):164-71.
1993: Paul Kubes; R Smith; M D Grisham; D N Granger
Neutrophil-mediated proteolysis. Differential roles for cathepsin G and elastase.
Inflammation 1993;17(3):321-32.
1993: Donna-Marie McCafferty; Paul Kubes; John L Wallace
Inhibition of platelet-activating factor-induced leukocyte adhesion in vivo by a leumedin.
European journal of pharmacology 1993;232(2-3):169-72.
1993: Paul Kubes
Ischemia-reperfusion in feline small intestine: a role for nitric oxide.
The American journal of physiology 1993;264(1 Pt 1):G143-9.
1992: H Asako; Paul Kubes; Bruce Baethge; R E Wolf; D Neil Granger
Reduction of leukocyte adherence and emigration by cyclosporine and L683,590 (FK506) in postcapillary venules.
Transplantation 1992;54(4):686-90.
1992: Paul Kubes; J Hunter; DN Granger
Ischemia/reperfusion-induced feline intestinal dysfunction: importance of granulocyte recruitment.
Gastroenterology 1992;103(3):807-12.
1992: H Asako; Paul Kubes; J Wallace; R E Wolf; D Neil Granger
Modulation of leukocyte adhesion in rat mesenteric venules by aspirin and salicylate.
Gastroenterology 1992;103(1):146-52.
1992: Paul Kubes
Nitric oxide modulates epithelial permeability in the feline small intestine.
The American journal of physiology 1992;262(6 Pt 1):G1138-42.
1992: H Asako; Paul Kubes; J Wallace; T Gaginella; R E Wolf; D Neil Granger
Indomethacin-induced leukocyte adhesion in mesenteric venules: role of lipoxygenase products.
The American journal of physiology 1992;262(5 Pt 1):G903-8.
1992: Paul Kubes; DN Granger
Nitric oxide modulates microvascular permeability.
The American journal of physiology 1992;262(2 Pt 2):H611-5.
1992: H Asako; Paul Kubes; Bruce Baethge; R E Wolf; D Neil Granger
Colchicine and methotrexate reduce leukocyte adherence and emigration in rat mesenteric venules.
Inflammation 1992;16(1):45-56.
1991: Paul Kubes; Matthew B Grisham; J A Barrowman; T Gaginella; D Neil Granger
Leukocyte-induced vascular protein leakage in cat mesentery.
The American journal of physiology 1991;261(6 Pt 2):H1872-9.
1991: M Suzuki; H Asako; Paul Kubes; S Jennings; Matthew B Grisham; D Neil Granger
Neutrophil-derived oxidants promote leukocyte adherence in postcapillary venules.
Microvascular research 1991;42(2):125-38.
1991: Paul Kubes; M Suzuki; D Neil Granger
Nitric oxide: an endogenous modulator of leukocyte adhesion.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(11):4651-5.
1991: Paul Kubes; K E Arfors; D Neil Granger
Platelet-activating factor-induced mucosal dysfunction: role of oxidants and granulocytes.
The American journal of physiology 1991;260(6 Pt 1):G965-71.
1991: Ronald J Korthuis; Paul Kubes; Patrick Tso; M Perry; D Neil Granger
Transport kinetics for superoxide dismutase and catalase between plasma and interstitial fluid in the rat small intestine.
Free radical biology & medicine 1991;11(3):293-8.
1990: Paul Kubes; G Ibbotson; J Russell; J L Wallace; D Neil Granger
Role of platelet-activating factor in ischemia/reperfusion-induced leukocyte adherence.
The American journal of physiology 1990;259(2 Pt 1):G300-5.
1990: Paul Kubes; M Suzuki; D Neil Granger
Platelet-activating factor-induced microvascular dysfunction: role of adherent leukocytes.
The American journal of physiology 1990;258(1 Pt 1):G158-63.