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Takahiro Kubota

Research Profile

Physiology

Geographic Areas

Japan

Chemicals & Drugs

Occupations

Pharmacogenetics

Procedures

Genes & Molecular Sequences

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Publications

TOP 3
Eiko Ohtake; Fumiko Kakihara; Naoko Matsumoto; Shogo Ozawa; Yasuo Ohno; Setsuo Hasegawa; Hiroshi Suzuki; Takahiro Kubota
Frequency distribution of phenol sulfotransferase 1A1 activity in platelet cells from healthy Japanese subjects.
Mikihiro Kusama; Takahiro Kubota; Yuji Matsukura; Kumi Matsuno; Seishi Ogawa; Yoshihiro Kanda; Tatsuji Iga
Influence of glutathione S-transferase A1 polymorphism on the pharmacokinetics of busulfan.
Takehito Yamamoto; Takahiro Kubota; Takeshi Ozeki; Mika Sawada; Shin-ichi Yokota; Yasuhiko Yamada; Yuji Kumagai; Tatsuji Iga
Effects of the CYP3A5 genetic polymorphism on the pharmacokinetics of diltiazem.

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All Publications

2006: Eiko Ohtake; Fumiko Kakihara; Naoko Matsumoto; Shogo Ozawa; Yasuo Ohno; Setsuo Hasegawa; Hiroshi Suzuki; Takahiro Kubota
Frequency distribution of phenol sulfotransferase 1A1 activity in platelet cells from healthy Japanese subjects.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2006;28(4):272-7.
2006: Mikihiro Kusama; Takahiro Kubota; Yuji Matsukura; Kumi Matsuno; Seishi Ogawa; Yoshihiro Kanda; Tatsuji Iga
Influence of glutathione S-transferase A1 polymorphism on the pharmacokinetics of busulfan.
Clinica chimica acta; international journal of clinical chemistry 2006;368(1-2):93-8.
2005: Takehito Yamamoto; Takahiro Kubota; Takeshi Ozeki; Mika Sawada; Shin-ichi Yokota; Yasuhiko Yamada; Yuji Kumagai; Tatsuji Iga
Effects of the CYP3A5 genetic polymorphism on the pharmacokinetics of diltiazem.
Clinica chimica acta; international journal of clinical chemistry 2005;362(1-2):147-54.
2005: Akihiro Ishiguro; Takahiro Kubota; Yoshihiro Soya; Hiroshi Sasaki; Osamu Yagyu; Yutaka Takarada; Tatsuji Iga
High-throughput detection of multiple genetic polymorphisms influencing drug metabolism with mismatch primers in allele-specific polymerase chain reaction.
Analytical biochemistry 2005;337(2):256-61.
2004: Akihiro Ishiguro; Takahiro Kubota; Hiroshi Sasaki; Tatsuji Iga
A long PCR assay to distinguish CYP2D6*5 and a novel CYP2D6 mutant allele associated with an 11-kb EcoRI haplotype.
Clinica chimica acta; international journal of clinical chemistry 2004;347(1-2):217-21.
2004: Takahiro Kubota; Akihito Nishida; Ken Takeuchi; Takayuki Iida; Hiromitsu Yokota; Katsumi Higashi; Kazuhiko Nakahara; Hiroyuki Hanai; Tatsuji Iga
Frequency distribution of thiopurine S-methyltransferase activity in red blood cells of a healthy Japanese population.
Therapeutic drug monitoring 2004;26(3):319-21.
2004: Akihiro Ishiguro; Takahiro Kubota; Hiroshi Ishikawa; Tatsuji Iga
Metabolic activity of dextromethorphan O-demethylation in healthy Japanese volunteers carrying duplicated CYP2D6 genes: duplicated allele of CYP2D6*10 does not increase CYP2D6 metabolic activity.
Clinica chimica acta; international journal of clinical chemistry 2004;344(1-2):201-4.
2004: Kumi Matsuno; Takahiro Kubota; Yuji Matsukura; Hiroshi Ishikawa; Tatsuji Iga
Genetic analysis of glutathione S-transferase A1 and T1 polymorphisms in a Japanese population.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2004;42(5):560-2.
2003: Kazuishi Sekino; Takahiro Kubota; Yuko Okada; Yasuhiko Yamada; Koujirou Yamamoto; Ryuya Horiuchi; Kenjirou Kimura; Tatsuji Iga
Effect of the single CYP2C9*3 allele on pharmacokinetics and pharmacodynamics of losartan in healthy Japanese subjects.
European journal of clinical pharmacology 2003;59(8-9):589-92.
2003: Takehito Yamamoto; Nobue Nagafuchi; Takeshi Ozeki; Takahiro Kubota; Hiroshi Ishikawa; Seishi Ogawa; Yasuhiko Yamada; Hisamaru Hirai; Tatsuji Iga
CYP3A4*18: it is not rare allele in Japanese population.
Drug metabolism and pharmacokinetics 2003;18(4):267-8.
2002: Akihito Nishida; Takahiro Kubota; Yasuhiko Yamada; Katsumi Higashi; Kiyoshi Kitamura; Kazuhiko Nakahara; Tatsuji Iga
Thiopurine S-methyltransferase activity in Japanese subjects: metabolic activity of 6-mercaptopurine 6-methylation in different TPMT genotypes.
Clinica chimica acta; international journal of clinical chemistry 2002;323(1-2):147-50.
2002: Yoshiharu Mitsunaga; Takahiro Kubota; Akihiro Ishiguro; Yasuhiko Yamada; Hiroshi Sasaki; Kan Chiba; Tatsuji Iga
Frequent occurrence of CYP2D6*10 duplication allele in a Japanese population.
Mutation research 2002;505(1-2):83-5.