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Alexei Kudin

Research Profile

Anatomy

Living Beings

Chemicals & Drugs

Physiology

Disorders

Temporal Lobe Epilepsy

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Publications

TOP 3
Stefan Vielhaber; Gábor Zsurka; Werner Zuschratter; Grazyna Debska-Vielhaber; Reinhard Dengler; Katja Kollewe; Cornelia Kornblum; Alexei P Kudin; Irina Minin; Viktoriya Peeva; S Schoeler; Stefanie Schreiber; Wolfram S Kunz
Mitofusin 2 mutations affect mitochondrial function by mitochondrial DNA depletion.
Alexei P Kudin; Bartłomiej Augustynek; Richard Kovács; Anja Kerstin Lehmann; Wolfram S Kunz
The contribution of thioredoxin-2 reductase and glutathione peroxidase to H(2)O(2) detoxification of rat brain mitochondria.
Dominika Malinska; Malgorzata Bejtka; Alexei P Kudin; Wolfram S Kunz
Changes in mitochondrial reactive oxygen species synthesis during differentiation of skeletal muscle cells.

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All Publications

2013: Stefan Vielhaber; Gábor Zsurka; Werner Zuschratter; Grazyna Debska-Vielhaber; Reinhard Dengler; Katja Kollewe; Cornelia Kornblum; Alexei P Kudin; Irina Minin; Viktoriya Peeva; S Schoeler; Stefanie Schreiber; Wolfram S Kunz
Mitofusin 2 mutations affect mitochondrial function by mitochondrial DNA depletion.
Acta neuropathologica 2013;125(2):245-56.
2012: Alexei P Kudin; Bartłomiej Augustynek; Richard Kovács; Anja Kerstin Lehmann; Wolfram S Kunz
The contribution of thioredoxin-2 reductase and glutathione peroxidase to H(2)O(2) detoxification of rat brain mitochondria.
Biochimica et biophysica acta 2012;1817(10):1901-6.
2012: Dominika Malinska; Malgorzata Bejtka; Alexei P Kudin; Wolfram S Kunz
Changes in mitochondrial reactive oxygen species synthesis during differentiation of skeletal muscle cells.
Mitochondrion 2012;12(1):144-8.
2010: Dominika Malinska; Bogusz Kulawiak; Alexei P Kudin; Richard Kovacs; Christine Huchzermeyer; Oliver Kann; Adam Szewczyk; Wolfram S Kunz
Complex III-dependent superoxide production of brain mitochondria contributes to seizure-related ROS formation.
Biochimica et biophysica acta 2010;1797(6-7):1163-70.
2009: Alexei P Kudin; Gábor Zsurka; Christian E Elger; Wolfram S Kunz
Mitochondrial involvement in temporal lobe epilepsy.
Experimental neurology 2009;218(2):326-32.
2009: Christian Frisch; Kerstin Hüsch; Frank Angenstein; Alexei P Kudin; Wolfram Kunz; Christian E Elger; Christoph Helmstaedter
Dose-dependent memory effects and cerebral volume changes after in utero exposure to valproate in the rat.
Epilepsia 2009;50(6):1432-41.
2009: Jolanta Skalska; Piotr Bednarczyk; Marta Piwońska; Bogusz Kulawiak; Grzegorz Wilczynski; Krzysztof Dołowy; Alexei P Kudin; Wolfram S Kunz; Adam Szewczyk
Calcium ions regulate K(+) uptake into brain mitochondria: The evidence for a novel potassium channel.
International journal of molecular sciences 2009;10(3):1104-20.
2009: Suzana Gispert; Filomena Ricciardi; Alexander Kurz; Mekhman Azizov; Hans-Hermann Hoepken; Dorothea Becker; Wolfgang Voos; Kristina Leuner; Walter E Müller; Alexei P Kudin; Wolfram S Kunz; Annabelle Zimmermann; Jochen Roeper; Dirk Wenzel; Marina Jendrach; Moisés García-Arencíbia; Javier Fernández-Ruiz; Leslie Huber; Hermann Rohrer; Miguel Barrera; Andreas S Reichert; Udo Rüb; Amy Chen; Robert L Nussbaum; Georg Auburger
Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration.
PloS one 2009;4(6):e5777.
2009: Dominika Malinska; Alexei P Kudin; Grazyna Debska-Vielhaber; Stefan Vielhaber; Wolfram S Kunz
Chapter 23 Quantification of superoxide production by mouse brain and skeletal muscle mitochondria.
Methods in enzymology 2009;456():419-37.
2008: Bogusz Kulawiak; Alexei P Kudin; Adam Szewczyk; Wolfram S Kunz
BK channel openers inhibit ROS production of isolated rat brain mitochondria.
Experimental neurology 2008;212(2):543-7.
2008: Alexei P Kudin; Dominika Malinska; Wolfram S Kunz
Sites of generation of reactive oxygen species in homogenates of brain tissue determined with the use of respiratory substrates and inhibitors.
Biochimica et biophysica acta 2008;1777(7-8):689-95.
2008: Stefan Vielhaber; Heiko G Niessen; Grazyna Debska-Vielhaber; Alexei P Kudin; Jörg Wellmer; Jörn Kaufmann; Mircea Ariel Schönfeld; Robert Fendrich; Wieland Willker; Dieter Leibfritz; Johannes Schramm; Christian E Elger; Hans-Jochen Heinze; Wolfram S Kunz
Subfield-specific loss of hippocampal N-acetyl aspartate in temporal lobe epilepsy.
Epilepsia 2008;49(1):40-50.
2007: M Baron; Alexei P Kudin; Wolfram S Kunz
Mitochondrial dysfunction in neurodegenerative disorders.
Biochemical Society transactions 2007;35(Pt 5):1228-31.
2007: Hue-Tran Hornig-Do; Jürgen-Christoph von Kleist-Retzow; Katrin Lanz; Claudia Wickenhauser; Alexei P Kudin; Wolfram S Kunz; Rudolf J Wiesner; Matthias Schauen
Human epidermal keratinocytes accumulate superoxide due to low activity of Mn-SOD, leading to mitochondrial functional impairment.
The Journal of investigative dermatology 2007;127(5):1084-93.
2007: Hans-Hermann Hoepken; Suzana Gispert; Blas Morales; Oliver Wingerter; Domenico Del Turco; Alexander Mülsch; Robert L Nussbaum; Klaus Müller; Stefan Dröse; Ulrich Brandt; Thomas Deller; Brunhilde Wirth; Alexei P Kudin; Wolfram S Kunz; Georg Auburger
Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6.
Neurobiology of disease 2007;25(2):401-11.
2007: Christian Frisch; Alexei P Kudin; Christian E Elger; Wolfram S Kunz; Christoph Helmstaedter
Amelioration of water maze performance deficits by topiramate applied during pilocarpine-induced status epilepticus is negatively dose-dependent.
Epilepsy research 2007;73(2):173-80.
2005: Heiko G Niessen; Frank Angenstein; Stefan Vielhaber; Christian Frisch; Alexei P Kudin; Christian E Elger; Hans-Jochen Heinze; Henning Scheich; Wolfram S Kunz
Volumetric magnetic resonance imaging of functionally relevant structural alterations in chronic epilepsy after pilocarpine-induced status epilepticus in rats.
Epilepsia 2005;46(7):1021-6.
2005: Alexei P Kudin; Grazyna Debska-Vielhaber; Wolfram S Kunz
Characterization of superoxide production sites in isolated rat brain and skeletal muscle mitochondria.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2005;59(4):163-8.
2004: Alexei P Kudin; Grazyna Debska-Vielhaber; Stefan Vielhaber; Christian E Elger; Wolfram S Kunz
The mechanism of neuroprotection by topiramate in an animal model of epilepsy.
Epilepsia 2004;45(12):1478-87.
2004: Alexei P Kudin; Nana Yaw-B Bimpong-Buta; Stefan Vielhaber; Christian E Elger; Wolfram S Kunz
Characterization of superoxide-producing sites in isolated brain mitochondria.
The Journal of biological chemistry 2004;279(6):4127-35.
2004: Wolfram S Kunz; Nana Yaw-B Bimpong-Buta; Alexei P Kudin; Christian E Elger
The role of mitochondria in epilepsy: implications for neurodegenerative diseases.
Toxicology mechanisms and methods 2004;14(1-2):19-23.
2003: Stefan Vielhaber; Alexei P Kudin; Tatiana A Kudina; Detlef Stiller; Henning Scheich; Ariel Schoenfeld; Helmut Feistner; Hans-Jochen Heinze; Christian E Elger; Wolfram S Kunz
Hippocampal N-acetyl aspartate levels do not mirror neuronal cell densities in creatine-supplemented epileptic rats.
The European journal of neuroscience 2003;18(8):2292-300.
2003: Stefan Vielhaber; Alexei P Kudin; Kirstin Winkler; Falk R Wiedemann; Rolf Schröder; Helmut Feistner; Hans-Jochen Heinze; Christian E Elger; Wolfram S Kunz
Is there mitochondrial dysfunction in amyotrophic lateral sclerosis skeletal muscle?
Annals of neurology 2003;53(5):686-7; author reply 687-8.
2002: Dmitry A Varlamov; Alexei P Kudin; Stefan Vielhaber; Rolf Schröder; Robert Sassen; Albert Becker; Dagmar Kunz; Karsten Haug; Johannes Rebstock; Armin Heils; Christian E Elger; Wolfram S Kunz
Metabolic consequences of a novel missense mutation of the mtDNA CO I gene.
Human molecular genetics 2002;11(16):1797-805.
2002: Alexei P Kudin; Tatiana A Kudina; Jan Seyfried; Stefan Vielhaber; Heinz Beck; Christian E Elger; Wolfram S Kunz
Seizure-dependent modulation of mitochondrial oxidative phosphorylation in rat hippocampus.
The European journal of neuroscience 2002;15(7):1105-14.
2002: Alexei P Kudin; Stefan Vielhaber; Christian E Elger; Wolfram S Kunz
Differences in flux control and reserve capacity of cytochrome c oxidase (COX) in human skeletal muscle and brain suggest different metabolic effects of mild COX deficiencies.
Molecular biology reports 2002;29(1-2):89-92.
2000: Wolfram S Kunz; Alexei P Kudin; Stefan Vielhaber; Ingmar Blümcke; W Zuschratter; Johannes Schramm; Heinz Beck; Christian E Elger
Mitochondrial complex I deficiency in the epileptic focus of patients with temporal lobe epilepsy.
Annals of neurology 2000;48(5):766-73.
2000: Wolfram S Kunz; Alexei P Kudin; Stefan Vielhaber; Christian E Elger; Giuseppe Attardi; Gaetano Villani
Flux control of cytochrome c oxidase in human skeletal muscle.
The Journal of biological chemistry 2000;275(36):27741-5.
2000: Stefan Vielhaber; Alexei P Kudin; Rolf Schröder; Christian E Elger; Wolfram S Kunz
Muscle fibres: applications for the study of the metabolic consequences of enzyme deficiencies in skeletal muscle.
Biochemical Society transactions 2000;28(2):159-64.
1999: Alexei P Kudin; Stefan Vielhaber; Heinz Beck; Christian E Elger; Wolfram S Kunz
Quantitative investigation of mitochondrial function in single rat hippocampal slices: a novel application of high-resolution respirometry and laser-excited fluorescence spectroscopy.
Brain research. Brain research protocols 1999;4(3):329-34.