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Jeffrey Kudlow

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Ping Huang; Shiuh-Rong Ho; Kai Wang; Bryan C Roessler; Fengxue Zhang; Yong Hu; Damon B Bowe; Jeffrey E Kudlow; Andrew J Paterson
Muscle-specific overexpression of NCOATGK, splice variant of O-GlcNAcase, induces skeletal muscle atrophy.
Shiuh-Rong Ho; Kai Wang; Thomas R Whisenhunt; Ping Huang; Xiaolin Zhu; Jeffrey E Kudlow; Andrew J Paterson
O-GlcNAcylation enhances FOXO4 transcriptional regulation in response to stress.
Kai Wang; Shiuh-Rong Ho; Weiming Mao; Ping Huang; Fengxue Zhang; Erik M Schwiebert; Jeffrey E Kudlow; Andrew J Paterson
Increased O-GlcNAc causes disrupted lens fiber cell differentiation and cataracts.

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2011: Ping Huang; Shiuh-Rong Ho; Kai Wang; Bryan C Roessler; Fengxue Zhang; Yong Hu; Damon B Bowe; Jeffrey E Kudlow; Andrew J Paterson
Muscle-specific overexpression of NCOATGK, splice variant of O-GlcNAcase, induces skeletal muscle atrophy.
American journal of physiology. Cell physiology 2011;300(3):C456-65.
2010: Shiuh-Rong Ho; Kai Wang; Thomas R Whisenhunt; Ping Huang; Xiaolin Zhu; Jeffrey E Kudlow; Andrew J Paterson
O-GlcNAcylation enhances FOXO4 transcriptional regulation in response to stress.
FEBS letters 2010;584(1):49-54.
2009: Kai Wang; Shiuh-Rong Ho; Weiming Mao; Ping Huang; Fengxue Zhang; Erik M Schwiebert; Jeffrey E Kudlow; Andrew J Paterson
Increased O-GlcNAc causes disrupted lens fiber cell differentiation and cataracts.
Biochemical and biophysical research communications 2009;387(1):70-6.
2008: Xiaoyong Yang; Pat P Ongusaha; Philip D Miles; Joyce C Havstad; Fengxue Zhang; W Venus So; Jeffrey E Kudlow; Robert H Michell; Jerrold M Olefsky; Seth J Field; Ronald M Evans
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance.
Nature 2008;451(7181):964-9.
2007: Fengxue Zhang; Andrew J Paterson; Ping Huang; Kai Wang; Jeffrey E Kudlow
Metabolic control of proteasome function.
Physiology (Bethesda, Md.) 2007;22():373-9.
2007: Fengxue Zhang; Yong Hu; Ping Huang; Clifford A Toleman; Andrew J Paterson; Jeffrey E Kudlow
Proteasome function is regulated by cyclic AMP-dependent protein kinase through phosphorylation of Rpt6.
The Journal of biological chemistry 2007;282(31):22460-71.
2006: Damon B Bowe; Andrea Sadlonova; Clifford A Toleman; Zdenek Novak; Yong Hu; Ping Huang; Shibani Mukherjee; Timothy Whitsett; Andra R Frost; Andrew J Paterson; Jeffrey E Kudlow
O-GlcNAc integrates the proteasome and transcriptome to regulate nuclear hormone receptors.
Molecular and cellular biology 2006;26(22):8539-50.
2006: Jeffrey E Kudlow
Post-translational modification by O-GlcNAc: another way to change protein function.
Journal of cellular biochemistry 2006;98(5):1062-75.
2006: Thomas R Whisenhunt; Xiaoyong Yang; Damon B Bowe; Andrew J Paterson; Brian A Van Tine; Jeffrey E Kudlow
Disrupting the enzyme complex regulating O-GlcNAcylation blocks signaling and development.
Glycobiology 2006;16(6):551-63.
2006: Clifford A Toleman; Andrew J Paterson; Jeffrey E Kudlow
Location and characterization of the O-GlcNAcase active site.
Biochimica et biophysica acta 2006;1760(5):829-39.
2006: Clifford A Toleman; Andrew J Paterson; Jeffrey E Kudlow
The histone acetyltransferase NCOAT contains a zinc finger-like motif involved in substrate recognition.
The Journal of biological chemistry 2006;281(7):3918-25.
2006: Clifford A Toleman; Andrew J Paterson; Ronald Shin; Jeffrey E Kudlow
Streptozotocin inhibits O-GlcNAcase via the production of a transition state analog.
Biochemical and biophysical research communications 2006;340(2):526-34.
2005: Meejeon Roh; Andrew J Paterson; Kan Liu; Joanne McAndrew; Edward Chin; Jeffrey E Kudlow
Proteolytic processing of TGFalpha redirects its mitogenic activity: the membrane-anchored form is autocrine, the secreted form is paracrine.
Biochimica et biophysica acta 2005;1743(3):231-42.
2005: K Wade Foster; Zhaoli Liu; Clinton D Nail; Xingnan Li; Thomas J Fitzgerald; Sarah K Bailey; Andra R Frost; Iuri D Louro; Tim M Townes; Andrew J Paterson; Jeffrey E Kudlow; Susan Lobo Ruppert; J Michael Ruppert
Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia.
Oncogene 2005;24(9):1491-500.
2004: Clifford A Toleman; Andrew J Paterson; Thomas R Whisenhunt; Jeffrey E Kudlow
Characterization of the histone acetyltransferase (HAT) domain of a bifunctional protein with activable O-GlcNAcase and HAT activities.
The Journal of biological chemistry 2004;279(51):53665-73.
2004: Yong Hu; Lacinda Riesland; Andrew J Paterson; Jeffrey E Kudlow
Phosphorylation of mouse glutamine-fructose-6-phosphate amidotransferase 2 (GFAT2) by cAMP-dependent protein kinase increases the enzyme activity.
The Journal of biological chemistry 2004;279(29):29988-93.
2004: Kan Liu; Andrew J Paterson; Fengxue Zhang; Joanne McAndrew; Ken-Ichiro Fukuchi; J Michael Wyss; Ling Peng; Yong Hu; Jeffrey E Kudlow
Accumulation of protein O-GlcNAc modification inhibits proteasomes in the brain and coincides with neuronal apoptosis in brain areas with high O-GlcNAc metabolism.
Journal of neurochemistry 2004;89(4):1044-55.
2004: Martin Hafner; Jutta Wenk; Arianna Nenci; Manolis Pasparakis; Karin Scharffetter-Kochanek; Neil Smyth; Thorsten Peters; Daniel Kess; Olaf Holtkötter; Pierre Shephard; Jeffrey E Kudlow; Hans Smola; Ingo Haase; Angela Schippers; Thomas Krieg; Werner Muller
Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyte-expressed protein.
Genesis (New York, N.Y. : 2000) 2004;38(4):176-81.
2003: Fengxue Zhang; Kaihong Su; Xiaoyong Yang; Damon B Bowe; Andrew J Paterson; Jeffrey E Kudlow
O-GlcNAc modification is an endogenous inhibitor of the proteasome.
Cell 2003;115(6):715-25.
2003: Brian A Van Tine; A J Patterson; Jeffrey E Kudlow
Assignment of N-acetyl-D-glucosaminidase (Mgea5) to rat chromosome 1q5 by tyramide fluorescence in situ hybridization (T-FISH): synteny between rat, mouse and human with Insulin Degradation Enzyme (IDE).
Cytogenetic and genome research 2003;103(1-2):202B.
2002: Robert J Konrad; Jeffrey E Kudlow
The role of O-linked protein glycosylation in beta-cell dysfunction.
International journal of molecular medicine 2002;10(5):535-9.
2002: Jeffrey E Kudlow
The O-GlcNAcase theory of diabetes: commentary on a candidate gene for diabetes.
Molecular genetics and metabolism 2002;77(1-2):1-2.
2002: Kan Liu; Andrew J Paterson; Robert J Konrad; A F Parlow; Shiro Jimi; Meejeon Roh; Edward Chin; Jeffrey E Kudlow
Streptozotocin, an O-GlcNAcase inhibitor, blunts insulin and growth hormone secretion.
Molecular and cellular endocrinology 2002;194(1-2):135-46.
2002: Xiaoyong Yang; Fengxue Zhang; Jeffrey E Kudlow
Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: coupling protein O-GlcNAcylation to transcriptional repression.
Cell 2002;110(1):69-80.
2002: Robert J Konrad; Fengxue Zhang; John E Hale; Michael D Knierman; Gerald Becker; Jeffrey E Kudlow
Alloxan is an inhibitor of the enzyme O-linked N-acetylglucosamine transferase.
Biochemical and biophysical research communications 2002;293(1):207-12.
2001: Robert J Konrad; joseph tolar; John E Hale; Michael D Knierman; Gerald Becker; Jeffrey E Kudlow
Purification of the O-glycosylated protein p135 and identification as O-GlcNAc transferase.
Biochemical and biophysical research communications 2001;288(5):1136-40.
2001: Xiaoyong Yang; Kaihong Su; MD Roos; Qing Chang; Andrew J Paterson; Jeffrey E Kudlow
O-linkage of N-acetylglucosamine to Sp1 activation domain inhibits its transcriptional capability.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(12):6611-6.
2001: Robert J Konrad; Irina Mikolaenko; joseph tolar; Kan Liu; Jeffrey E Kudlow
The potential mechanism of the diabetogenic action of streptozotocin: inhibition of pancreatic beta-cell O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase.
The Biochemical journal 2001;356(Pt 1):31-41.
2001: Meejeon Roh; Andrew J Paterson; Sylvia Asa; Edward Chin; Jeffrey E Kudlow
Stage-sensitive blockade of pituitary somatomammotrope development by targeted expression of a dominant negative epidermal growth factor receptor in transgenic mice.
Molecular endocrinology (Baltimore, Md.) 2001;15(4):600-13.
2000: Vijayakrishna K Gadi; S D Alexander; Jeffrey E Kudlow; Paula W Allan; William B Parker; Eric J Sorscher
In vivo sensitization of ovarian tumors to chemotherapy by expression of E. coli purine nucleoside phosphorylase in a small fraction of cells.
Gene therapy 2000;7(20):1738-43.
2000: Robert J Konrad; Kan Liu; Jeffrey E Kudlow
A modified method of islet isolation preserves the ability of pancreatic islets to increase protein O-glycosylation in response to glucose and streptozotocin.
Archives of biochemistry and biophysics 2000;381(1):92-8.
2000: I Han; Eok-Soo Oh; Jeffrey E Kudlow
Responsiveness of the state of O-linked N-acetylglucosamine modification of nuclear pore protein p62 to the extracellular glucose concentration.
The Biochemical journal 2000;350 Pt 1():109-14.
2000: Qing Chang; Kaihong Su; J R Baker; Xiaoyong Yang; Andrew J Paterson; Jeffrey E Kudlow
Phosphorylation of human glutamine:fructose-6-phosphate amidotransferase by cAMP-dependent protein kinase at serine 205 blocks the enzyme activity.
The Journal of biological chemistry 2000;275(29):21981-7.
2000: Kaihong Su; Xiaoyong Yang; MD Roos; Andrew J Paterson; Jeffrey E Kudlow
Human Sug1/p45 is involved in the proteasome-dependent degradation of Sp1.
The Biochemical journal 2000;348 Pt 2():281-9.
2000: K Liu; Andrew J Paterson; Edward Chin; Jeffrey E Kudlow
Glucose stimulates protein modification by O-linked GlcNAc in pancreatic beta cells: linkage of O-linked GlcNAc to beta cell death.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(6):2820-5.
2000: Robert J Konrad; Karen M Janowski; Jeffrey E Kudlow
Glucose and streptozotocin stimulate p135 O-glycosylation in pancreatic islets.
Biochemical and biophysical research communications 2000;267(1):26-32.
1999: W Xie; Louise T Chow; Andrew J Paterson; Edward Chin; Jeffrey E Kudlow
Conditional expression of the ErbB2 oncogene elicits reversible hyperplasia in stratified epithelia and up-regulation of TGFalpha expression in transgenic mice.
Oncogene 1999;18(24):3593-607.
1999: Kaihong Su; MD Roos; Xiaoyong Yang; I Han; Andrew J Paterson; Jeffrey E Kudlow
An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro.
The Journal of biological chemistry 1999;274(21):15194-202.
1999: Dan Wang; Jeffrey E Kudlow
Purification and characterization of TEF1, a transcription factor that controls the human transforming growth factor-alpha promoter.
Biochimica et biophysica acta 1999;1449(1):50-62.
1998: MD Roos; W Xie; Kaihong Su; J A Clark; Xiaoyong Yang; Edward Chin; Andrew J Paterson; Jeffrey E Kudlow
Streptozotocin, an analog of N-acetylglucosamine, blocks the removal of O-GlcNAc from intracellular proteins.
Proceedings of the Association of American Physicians 1998;110(5):422-32.
1998: W Xie; F Li; Jeffrey E Kudlow; C Wu
Expression of the integrin-linked kinase (ILK) in mouse skin: loss of expression in suprabasal layers of the epidermis and up-regulation by erbB-2.
The American journal of pathology 1998;153(2):367-72.
1998: David S H Bell; Jeffrey E Kudlow; M Tidwell
Health-care charges generated by patients with diabetes.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 1998;4(4):237-9.
1998: W Xie; X Wu; Louise T Chow; Edward Chin; Andrew J Paterson; Jeffrey E Kudlow
Targeted expression of activated erbB-2 to the epidermis of transgenic mice elicits striking developmental abnormalities in the epidermis and hair follicles.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(4):313-25.
1998: I Han; MD Roos; Jeffrey E Kudlow
Interaction of the transcription factor Sp1 with the nuclear pore protein p62 requires the C-terminal domain of p62.
Journal of cellular biochemistry 1998;68(1):50-61.
1997: W Xie; Andrew J Paterson; Edward Chin; Lisle Nabell; Jeffrey E Kudlow
Targeted expression of a dominant negative epidermal growth factor receptor in the mammary gland of transgenic mice inhibits pubertal mammary duct development.
Molecular endocrinology (Baltimore, Md.) 1997;11(12):1766-81.
1997: MD Roos; Kaihong Su; J R Baker; Jeffrey E Kudlow
O glycosylation of an Sp1-derived peptide blocks known Sp1 protein interactions.
Molecular and cellular biology 1997;17(11):6472-80.
1997: W Xie; Kaihong Su; D Wang; Andrew J Paterson; Jeffrey E Kudlow
MDA468 growth inhibition by EGF is associated with the induction of the cyclin-dependent kinase inhibitor p21WAF1.
Anticancer research 1997;17(4A):2627-33.
1997: Dan Wang; T H Shin; Jeffrey E Kudlow
Transcription factor AP-2 controls transcription of the human transforming growth factor-alpha gene.
The Journal of biological chemistry 1997;272(22):14244-50.
1997: I Han; Jeffrey E Kudlow
Reduced O glycosylation of Sp1 is associated with increased proteasome susceptibility.
Molecular and cellular biology 1997;17(5):2550-8.
1997: Peter P Sayeski; Dan Wang; Kaihong Su; I O Han; Jeffrey E Kudlow
Cloning and partial characterization of the mouse glutamine:fructose-6-phosphate amidotransferase (GFAT) gene promoter.
Nucleic acids research 1997;25(7):1458-66.
1996: P P Sayeski; Jeffrey E Kudlow
Glucose metabolism to glucosamine is necessary for glucose stimulation of transforming growth factor-alpha gene transcription.
The Journal of biological chemistry 1996;271(25):15237-43.
1996: MD Roos; I Han; Andrew J Paterson; Jeffrey E Kudlow
Role of glucosamine synthesis in the stimulation of TGF-alpha gene transcription by glucose and EGF.
The American journal of physiology 1996;270(3 Pt 1):C803-11.
1996: Joseph R Biggs; Jeffrey E Kudlow; Andrew Kraft
The role of the transcription factor Sp1 in regulating the expression of the WAF1/CIP1 gene in U937 leukemic cells.
The Journal of biological chemistry 1996;271(2):901-6.
1995: J McAndrew; Andrew J Paterson; Sylvia Asa; Kevin J Mccarthy; Jeffrey E Kudlow
Targeting of transforming growth factor-alpha expression to pituitary lactotrophs in transgenic mice results in selective lactotroph proliferation and adenomas.
Endocrinology 1995;136(10):4479-88.
1995: T H Shin; Andrew J Paterson; Jeffrey E Kudlow
p53 stimulates transcription from the human transforming growth factor alpha promoter: a potential growth-stimulatory role for p53.
Molecular and cellular biology 1995;15(9):4694-701.
1995: Andrew J Paterson; Jeffrey E Kudlow
Regulation of glutamine:fructose-6-phosphate amidotransferase gene transcription by epidermal growth factor and glucose.
Endocrinology 1995;136(7):2809-16.
1995: W R Staggers; Andrew J Paterson; Jeffrey E Kudlow
Sequence of the functional human keratin K14 promoter.
Gene 1995;153(2):297-8.
1994: T H Shin; Jeffrey E Kudlow
Identification and characterization of the human transforming growth factor-alpha initiator.
Molecular endocrinology (Baltimore, Md.) 1994;8(6):704-12.
1994: P P Sayeski; Andrew J Paterson; Jeffrey E Kudlow
The murine glutamine:fructose-6-phosphate amidotransferase-encoding cDNA sequence.
Gene 1994;140(2):289-90.
1994: L M Nabell; R H Raja; P P Sayeski; Andrew J Paterson; Jeffrey E Kudlow
Human immunodeficiency virus 1 Tat stimulates transcription of the transforming growth factor alpha gene in an epidermal growth factor-dependent manner.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(1):87-93.
1993: Russell B Myers; Jeffrey E Kudlow; William E Grizzle
Expression of transforming growth factor-alpha, epidermal growth factor and the epidermal growth factor receptor in adenocarcinoma of the prostate and benign prostatic hyperplasia.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1993;6(6):733-7.
1993: Matthew C Daniels; P Kansal; T M Smith; Andrew J Paterson; Jeffrey E Kudlow; Donald A McClain
Glucose regulation of transforming growth factor-alpha expression is mediated by products of the hexosamine biosynthesis pathway.
Molecular endocrinology (Baltimore, Md.) 1993;7(8):1041-8.
1992: D K Driman; M S Kobrin; Jeffrey E Kudlow; Sylvia Asa
Transforming growth factor-alpha in normal and neoplastic human endocrine tissues.
Human pathology 1992;23(12):1360-5.
1992: Donald A McClain; Andrew J Paterson; MD Roos; X Wei; Jeffrey E Kudlow
Glucose and glucosamine regulate growth factor gene expression in vascular smooth muscle cells.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(17):8150-4.
1992: T H Shin; Andrew J Paterson; J H Grant; A A Meluch; Jeffrey E Kudlow
5-Azacytidine treatment of HA-A melanoma cells induces Sp1 activity and concomitant transforming growth factor alpha expression.
Molecular and cellular biology 1992;12(9):3998-4006.
1992: B Borgundvaag; Jeffrey E Kudlow; S G Mueller; Susan R George
Dopamine receptor activation inhibits estrogen-stimulated transforming growth factor-alpha gene expression and growth in anterior pituitary, but not in uterus.
Endocrinology 1992;130(6):3453-8.
1991: S G Mueller; Jeffrey E Kudlow
Transforming growth factor-beta (TGF beta) inhibits TGF alpha expression in bovine anterior pituitary-derived cells.
Molecular endocrinology (Baltimore, Md.) 1991;5(10):1439-46.
1991: R H Raja; Andrew J Paterson; T H Shin; Jeffrey E Kudlow
Transcriptional regulation of the human transforming growth factor-alpha gene.
Molecular endocrinology (Baltimore, Md.) 1991;5(4):514-20.
1990: S G Mueller; Andrew J Paterson; Jeffrey E Kudlow
Transforming growth factor alpha in arterioles: cell surface processing of its precursor by elastases.
Molecular and cellular biology 1990;10(9):4596-602.
1990: Jeffrey E Kudlow; J D Bjorge
TGF alpha in normal physiology.
Seminars in cancer biology 1990;1(4):293-302.
1989: S G Mueller; M S Kobrin; Andrew J Paterson; Jeffrey E Kudlow
Transforming growth factor-alpha expression in the anterior pituitary gland: regulation by epidermal growth factor and phorbol ester in dispersed cells.
Molecular endocrinology (Baltimore, Md.) 1989;3(6):976-83.
1989: Derek K Lobb; M S Kobrin; Jeffrey E Kudlow; JH Dorrington
Transforming growth factor-alpha in the adult bovine ovary: identification in growing ovarian follicles.
Biology of reproduction 1989;40(5):1087-93.
1989: Jeffrey E Kudlow; A W Leung; M S Kobrin; Andrew J Paterson; Sylvia Asa
Transforming growth factor-alpha in the mammalian brain. Immunohistochemical detection in neurons and characterization of its mRNA.
The Journal of biological chemistry 1989;264(7):3880-3.
1989: J D Bjorge; Andrew J Paterson; Jeffrey E Kudlow
Phorbol ester or epidermal growth factor (EGF) stimulates the concurrent accumulation of mRNA for the EGF receptor and its ligand transforming growth factor-alpha in a breast cancer cell line.
The Journal of biological chemistry 1989;264(7):4021-7.
1989: J D Bjorge; Jeffrey E Kudlow; G B Mills; Andrew J Paterson
Inhibition of stimulus-dependent epidermal growth factor receptor and transforming growth factor-alpha mRNA accumulation by the protein kinase C inhibitor staurosporine.
FEBS letters 1989;243(2):404-8.
1988: Jeffrey E Kudlow; J D Bjorge; M S Kobrin; Andrew J Paterson
Regulation of EGF receptor and transforming growth factor-alpha expression.
Advances in experimental medicine and biology 1988;234():105-26.
1987: Jeffrey E Kudlow; M S Kobrin; A F Purchio; D R Twardzik; E R Hernandez; Sylvia Asa; Eli Y Adashi
Ovarian transforming growth factor-alpha gene expression: immunohistochemical localization to the theca-interstitial cells.
Endocrinology 1987;121(4):1577-9.
1987: M S Kobrin; Sylvia Asa; J Samsoondar; Jeffrey E Kudlow
Alpha-transforming growth factor in the bovine anterior pituitary gland: secretion by dispersed cells and immunohistochemical localization.
Endocrinology 1987;121(4):1412-6.
1987: J D Bjorge; Jeffrey E Kudlow
Epidermal growth factor receptor synthesis is stimulated by phorbol ester and epidermal growth factor. Evidence for a common mechanism.
The Journal of biological chemistry 1987;262(14):6615-22.
1987: J Samsoondar; Jeffrey E Kudlow
Partial purification of an adrenal growth factor produced by normal bovine anterior pituitary cells in culture.
Endocrinology 1987;120(3):929-35.
1986: M S Kobrin; J Samsoondar; Jeffrey E Kudlow
Alpha-transforming growth factor secreted by untransformed bovine anterior pituitary cells in culture. II. Identification using a sequence-specific monoclonal antibody.
The Journal of biological chemistry 1986;261(31):14414-9.
1986: J Samsoondar; M S Kobrin; Jeffrey E Kudlow
Alpha-transforming growth factor secreted by untransformed bovine anterior pituitary cells in culture. I. Purification from conditioned medium.
The Journal of biological chemistry 1986;261(31):14408-13.
1986: Jeffrey E Kudlow; C Y Cheung; J D Bjorge
Epidermal growth factor stimulates the synthesis of its own receptor in a human breast cancer cell line.
The Journal of biological chemistry 1986;261(9):4134-8.
1984: Jeffrey E Kudlow; M J Khosravi; M S Kobrin; W W Mak
Inability of anti-epidermal growth factor receptor monoclonal antibody to block "autocrine" growth stimulation in transforming growth factor-secreting melanoma cells.
The Journal of biological chemistry 1984;259(19):11895-900.
1984: Jeffrey E Kudlow; M S Kobrin
Secretion of epidermal growth factor-like mitogens by cultured cells from bovine anterior pituitary glands.
Endocrinology 1984;115(3):911-7.