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Martin Kuehne

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TOP 3
Martin E Kuehne; Rory Waterman
rac-18-Meth-oxy-coronaridine hydro-chloride.
Christopher J Pace; Stanley D D Glick; Isabelle M Maisonneuve; Li-Wen He; Patrick A Jokiel; Martin E Kuehne; Mark W Fleck
Novel iboga alkaloid congeners block nicotinic receptors and reduce drug self-administration.
Martin E Kuehne; William G Bornmann; Istvan Markó; Yong Qin; Karen L LeBoulluec; Deborah A Frasier; Feng Xu; Tshilundu Mulamba; Carol L Ensinger; Linda S Borman; Anne E Huot; Christopher Exon; Fred T Bizzarro; Julia B Cheung; Susan Bane
Syntheses and biological evaluation of vinblastine congeners.

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All Publications

2012: Martin E Kuehne; Rory Waterman
rac-18-Meth-oxy-coronaridine hydro-chloride.
Acta crystallographica. Section E, Structure reports online 2012;68(Pt 4):o1041.
2004: Christopher J Pace; Stanley D D Glick; Isabelle M Maisonneuve; Li-Wen He; Patrick A Jokiel; Martin E Kuehne; Mark W Fleck
Novel iboga alkaloid congeners block nicotinic receptors and reduce drug self-administration.
European journal of pharmacology 2004;492(2-3):159-67.
2003: Martin E Kuehne; William G Bornmann; Istvan Markó; Yong Qin; Karen L LeBoulluec; Deborah A Frasier; Feng Xu; Tshilundu Mulamba; Carol L Ensinger; Linda S Borman; Anne E Huot; Christopher Exon; Fred T Bizzarro; Julia B Cheung; Susan Bane
Syntheses and biological evaluation of vinblastine congeners.
Organic & biomolecular chemistry 2003;1(12):2120-36.
2003: Martin E Kuehne; Liwen He; Patrick A Jokiel; C J Pace; Mark W Fleck; Isabelle M Maisonneuve; Stanley D D Glick; Jean M Bidlack
Synthesis and biological evaluation of 18-methoxycoronaridine congeners. Potential antiaddiction agents.
Journal of medicinal chemistry 2003;46(13):2716-30.
2002: Sabarni K Chatterjee; Julien Laffray; Pruthvi Patel; Rudravajhala Ravindra; Yong Qin; Martin E Kuehne; Susan Bane
Interaction of tubulin with a new fluorescent analogue of vinblastine.
Biochemistry 2002;41(47):14010-8.
2002: Wenjiang Zhang; Yamini Ramamoorthy; Rachel F Tyndale; Stanley D D Glick; Isabelle M Maisonneuve; Martin E Kuehne; Edward M Sellers
Metabolism of 18-methoxycoronaridine, an ibogaine analog, to 18-hydroxycoronaridine by genetically variable CYP2C19.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(6):663-9.
2001: Martin E Kuehne; Yong Qin; A E Huot; Susan Bane
The syntheses of 16a'-homo-leurosidine and 16a'-homo-vinblastine. Generation of atropisomers.
The Journal of organic chemistry 2001;66(16):5317-28.
2001: Martin E Kuehne; S D Cowen; F Xu; L S Borman
Syntheses of 5a'-homo-vinblastine and congeners designed to establish structural determinants for isolation of atropisomers.
The Journal of organic chemistry 2001;66(16):5303-16.
2001: Martin E Kuehne; W Dai; YL Li
New ferrocenyl chiral auxiliary substituents for amines: applications to syntheses of mossambine and vinblastine.
The Journal of organic chemistry 2001;66(5):1560-6.
2000: Martin E Kuehne; YL Li; C Q Wei
Biogenetic syntheses of kopsijasminilam and deoxykopsijasminilam.
The Journal of organic chemistry 2000;65(20):6434-40.
1999: Martin E Kuehne; YL Li
A biomimetic synthesis of the pauciflorine A and B skeleton.
Organic letters 1999;1(11):1749-50.
1998: Stanley D D Glick; Isabelle M Maisonneuve; Kathleen Rutledge; K A Fritz; UK Bandarage; Martin E Kuehne
18-Methoxycoronardine attenuates nicotine-induced dopamine release and nicotine preferences in rats.
Psychopharmacology 1998;139(3):274-80.
1998: D Wei; Isabelle M Maisonneuve; Martin E Kuehne; Stanley D D Glick
Acute iboga alkaloid effects on extracellular serotonin (5-HT) levels in nucleus accumbens and striatum in rats.
Brain research 1998;800(2):260-8.
1997: Isabelle M Maisonneuve; Kathleen Rutledge; G L Mann; UK Bandarage; Martin E Kuehne; Stanley D D Glick
Time-dependent interactions between iboga agents and cocaine.
European journal of pharmacology 1997;336(2-3):123-6.
1997: Amir H Rezvani; David H Overstreet; Y Yang; Isabelle M Maisonneuve; UK Bandarage; Martin E Kuehne; Stanley D D Glick
Attenuation of alcohol consumption by a novel nontoxic ibogaine analogue (18-methoxycoronaridine) in alcohol-preferring rats.
Pharmacology, biochemistry, and behavior 1997;58(2):615-9.
1996: R T Layer; Phil Skolnick; C M Bertha; U K Bandarage; Martin E Kuehne; P Popik
Structurally modified ibogaine analogs exhibit differing affinities for NMDA receptors.
European journal of pharmacology 1996;309(2):159-65.
1996: Stanley D D Glick; Martin E Kuehne; Isabelle M Maisonneuve; U K Bandarage; H H Molinari
18-Methoxycoronaridine, a non-toxic iboga alkaloid congener: effects on morphine and cocaine self-administration and on mesolimbic dopamine release in rats.
Brain research 1996;719(1-2):29-35.
1995: Wayne D Bowen; BJ Vilner; Wanda Williams; C M Bertha; Martin E Kuehne; Arthur E Jacobson
Ibogaine and its congeners are sigma 2 receptor-selective ligands with moderate affinity.
European journal of pharmacology 1995;279(1):R1-3.
1994: Stanley D D Glick; Martin E Kuehne; J Raucci; T E Wilson; D Larson; Richard W Keller; Jeffrey N Carlson
Effects of iboga alkaloids on morphine and cocaine self-administration in rats: relationship to tremorigenic effects and to effects on dopamine release in nucleus accumbens and striatum.
Brain research 1994;657(1-2):14-22.
1993: L S Borman; W G Bornmann; Martin E Kuehne
Modulation of drug cytotoxicity in wild-type and multidrug-resistant tumor cells by stereoisomeric series of C-20'-vinblastine congeners that lack antimicrotubule activity.
Cancer chemotherapy and pharmacology 1993;31(5):343-9.
1992: Darlene Deecher; Milt Teitler; D M Soderlund; W G Bornmann; Martin E Kuehne; Stanley D D Glick
Mechanisms of action of ibogaine and harmaline congeners based on radioligand binding studies.
Brain research 1992;571(2):242-7.
1989: L S Borman; Martin E Kuehne
Specific alterations in the biological activities of C-20'-modified vinblastine congeners.
Biochemical pharmacology 1989;38(5):715-24.
1988: L S Borman; Martin E Kuehne; P A Matson; I Marko; T C Zebovitz
Single site-modified congeners of vinblastine dissociate its various anti-microtubule actions.
The Journal of biological chemistry 1988;263(15):6945-8.