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Donald Kufe

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
60
Kharbanda, Surender
56
Weichselbaum, Ralph
45
Weichselbaum, Ralph
42
Datta, Rakesh
39
Spriggs, David
33
Yuan, Zhi-Min
26
Pandey, Pramod
23
Mauceri, Helena
23
Beckett, Michael
21
Hayes, Daniel
20
Hallahan, Dennis
18
Avigan, David
18
Bharti, Ajit
18
Ren, Jian
18
Raina, Deepak

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Publications

TOP 3
Joshi Maya Datt; Ahmad Rehan; Yin Li; Raina Deepak; Rajabi Hasan; Bubley Glenn; Kharbanda Surender; Kufe Donald
MUC1 oncoprotein is a druggable target in human prostate cancer cells.
Ahmad Rehan; Raina Deepak; Joshi Maya Datt; Kawano Takeshi; Ren Jian; Kharbanda Surender; Kufe Donald
MUC1-C oncoprotein functions as a direct activator of the nuclear factor-kappaB p65 transcription factor.
Weichselbaum R R; Kufe D
Translation of the radio- and chemo-inducible TNFerade vector to the treatment of human cancers.

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All Publications

2009: Joshi Maya Datt; Ahmad Rehan; Yin Li; Raina Deepak; Rajabi Hasan; Bubley Glenn; Kharbanda Surender; Kufe Donald
MUC1 oncoprotein is a druggable target in human prostate cancer cells.
Molecular cancer therapeutics 2009;8(11):3056-65.
2009: Ahmad Rehan; Raina Deepak; Joshi Maya Datt; Kawano Takeshi; Ren Jian; Kharbanda Surender; Kufe Donald
MUC1-C oncoprotein functions as a direct activator of the nuclear factor-kappaB p65 transcription factor.
Cancer research 2009;69(17):7013-21.
2009: Weichselbaum R R; Kufe D
Translation of the radio- and chemo-inducible TNFerade vector to the treatment of human cancers.
Cancer gene therapy 2009;16(8):609-19.
2009: Raina Deepak; Ahmad Rehan; Joshi Maya Datt; Yin Li; Wu Zekui; Kawano Takeshi; Vasir Baldev; Avigan David; Kharbanda Surender; Kufe Donald
Direct targeting of the mucin 1 oncoprotein blocks survival and tumorigenicity of human breast carcinoma cells.
Cancer research 2009;69(12):5133-41.
2009: Yin Li; Kharbanda Surender; Kufe Donald
MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation.
International journal of oncology 2009;34(6):1691-9.
2009: Mauceri H J; Beckett M A; Liang H; Sutton H G; Pitroda S; Galka E; Efimova E; Darga T; Khodarev N N; King C R; Posner M C; Hellman S; Kufe D W; Weichselbaum R R
Translational strategies exploiting TNF-alpha that sensitize tumors to radiation therapy.
Cancer gene therapy 2009;16(4):373-81.
2008: Raina Deepak; Ahmad Rehan; Chen Dongshu; Kumar Shailendra; Kharbanda Surender; Kufe Donald
MUC1 oncoprotein suppresses activation of the ARF-MDM2-p53 pathway.
Cancer biology & therapy 2008;7(12):1959-67.
2008: Agata Naoki; Ahmad Rehan; Kawano Takeshi; Raina Deepak; Kharbanda Surender; Kufe Donald
MUC1 oncoprotein blocks death receptor-mediated apoptosis by inhibiting recruitment of caspase-8.
Cancer research 2008;68(15):6136-44.
2008: Kawano Takeshi; Ahmad Rehan; Nogi Hiroko; Agata Naoki; Anderson Kenneth; Kufe Donald
MUC1 oncoprotein promotes growth and survival of human multiple myeloma cells.
International journal of oncology 2008;33(1):153-9.
2008: Vasir Baldev; Wu Zekui; Crawford Keith; Rosenblatt Jacalyn; Zarwan Corrine; Bissonnette Adam; Kufe Donald; Avigan David
Fusions of dendritic cells with breast carcinoma stimulate the expansion of regulatory T cells while concomitant exposure to IL-12, CpG oligodeoxynucleotides, and anti-CD3/CD28 promotes the expansion of activated tumor reactive cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(1):808-21.
2008: Ahmad Rehan; Raina Deepak; Meyer Colin; Kufe Donald
Triterpenoid CDDO-methyl ester inhibits the Janus-activated kinase-1 (JAK1)-->signal transducer and activator of transcription-3 (STAT3) pathway by direct inhibition of JAK1 and STAT3.
Cancer research 2008;68(8):2920-6.
2008: Kufe Donald W
Targeting the human MUC1 oncoprotein: a tale of two proteins.
Cancer biology & therapy 2008;7(1):81-4.
2007: Kawano Takeshi; Ito Masaki; Raina Deepak; Wu Zekui; Rosenblatt Jacalyn; Avigan David; Stone Richard; Kufe Donald
MUC1 oncoprotein regulates Bcr-Abl stability and pathogenesis in chronic myelogenous leukemia cells.
Cancer research 2007;67(24):11576-84.
2007: Ahmad Rehan; Raina Deepak; Trivedi Vishal; Ren Jian; Rajabi Hasan; Kharbanda Surender; Kufe Donald
MUC1 oncoprotein activates the IkappaB kinase beta complex and constitutive NF-kappaB signalling.
Nature cell biology 2007;9(12):1419-27.
2007: Katdare Mukta; Efimova Elena V; Labay Edwardine; Khodarev Nikolai N; Darga Thomas E; Garofalo Michael; Nakamura Satoaki; Kufe Donald W; Posner Mitchell C; Weichselbaum Ralph R
Diverse TNFalpha-induced death pathways are enhanced by inhibition of NF-kappaB.
International journal of oncology 2007;31(6):1519-28.
2007: Avigan David E; Vasir Baldev; George Daniel J; Oh William K; Atkins Michael B; McDermott David F; Kantoff Philip W; Figlin Robert A; Vasconcelles Michael J; Xu Yuanxin; Kufe Donald; Bukowski Ronald M
Phase I/II study of vaccination with electrofused allogeneic dendritic cells/autologous tumor-derived cells in patients with stage IV renal cell carcinoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2007;30(7):749-61.
2007: Ramasamy Selvi; Duraisamy Sekhar; Barbashov Sergei; Kawano Takeshi; Kharbanda Surender; Kufe Donald
The MUC1 and galectin-3 oncoproteins function in a microRNA-dependent regulatory loop.
Molecular cell 2007;27(6):992-1004.
2007: Duraisamy Sekhar; Kufe Turner; Ramasamy Selvi; Kufe Donald
Evolution of the human MUC1 oncoprotein.
International journal of oncology 2007;31(3):671-7.
2007: Yamini Bakhtiar; Yu Xiaohong; Dolan M Eileen; Wu Michael H; Darga Thomas E; Kufe Donald W; Weichselbaum Ralph R
Inhibition of nuclear factor-kappaB activity by temozolomide involves O6-methylguanine induced inhibition of p65 DNA binding.
Cancer research 2007;67(14):6889-98.
2007: Leng Yumei; Cao Cheng; Ren Jian; Huang Lei; Chen Dongshu; Ito Masaki; Kufe Donald
Nuclear import of the MUC1-C oncoprotein is mediated by nucleoporin Nup62.
The Journal of biological chemistry 2007;282(27):19321-30.
2007: Wei Xiaolong; Xu Hai; Kufe Donald
Human mucin 1 oncoprotein represses transcription of the p53 tumor suppressor gene.
Cancer research 2007;67(4):1853-8.
2007: Lerma Enrica I; Nguyen Viet-Anh; Wang Tao; Tipping Alex; Melo Junia V; Kufe Donald; Austin David J; Deisseroth Albert
Novel compounds with antiproliferative activity against imatinib-resistant cell lines.
Molecular cancer therapeutics 2007;6(2):655-66.
2007: Kawano Takeshi; Agata Naoki; Kharbanda Surender; Avigan David; Kufe Donald
A novel isocoumarin derivative induces mitotic phase arrest and apoptosis of human multiple myeloma cells.
Cancer chemotherapy and pharmacology 2007;59(3):329-35.
2007: Sha Shi-Ken; Sato Takuji; Kobayashi Hidetaka; Ishigaki Machiyo; Yamamoto Sayaka; Sato Hitoshi; Takada Asako; Nakajyo Sigetosi; Mochizuki Yasuo; Friedman Jonathan M; Cheng Fong-Chi; Okura Takashi; Kimura Ryohei; Kufe Donald W; Vonhoff Daniel D; Kawabe Takumi
Cell cycle phenotype-based optimization of G2-abrogating peptides yields CBP501 with a unique mechanism of action at the G2 checkpoint.
Molecular cancer therapeutics 2007;6(1):147-53.
2007: Yin Li; Kharbanda Surender; Kufe Donald
Mucin 1 oncoprotein blocks hypoxia-inducible factor 1alpha activation in a survival response to hypoxia.
The Journal of biological chemistry 2007;282(1):257-66.
2007: Imam Syed Z; Indig Fred E; Cheng Wen-Hsing; Saxena Satya P; Stevnsner Tinna; Kufe Donald; Bohr Vilhelm A
Cockayne syndrome protein B interacts with and is phosphorylated by c-Abl tyrosine kinase.
Nucleic acids research 2007;35(15):4941-51.
2006: Ren Jian; Raina Deepak; Chen Wen; Li Guilan; Huang Lei; Kufe Donald
MUC1 oncoprotein functions in activation of fibroblast growth factor receptor signaling.
Molecular cancer research : MCR 2006;4(11):873-83.
2006: Ahmad Rehan; Raina Deepak; Meyer Colin; Kharbanda Surender; Kufe Donald
Triterpenoid CDDO-Me blocks the NF-kappaB pathway by direct inhibition of IKKbeta on Cys-179.
The Journal of biological chemistry 2006;281(47):35764-9.
2006: Raina Deepak; Ahmad Rehan; Kumar Shailendra; Ren Jian; Yoshida Kiyotsugu; Kharbanda Surender; Kufe Donald
MUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damage.
The EMBO journal 2006;25(16):3774-83.
2006: Duraisamy Sekhar; Ramasamy Selvi; Kharbanda Surender; Kufe Donald
Distinct evolution of the human carcinoma-associated transmembrane mucins, MUC1, MUC4 AND MUC16.
Gene 2006;373():28-34.
2006: Wei Xiaolong; Xu Hai; Kufe Donald
MUC1 oncoprotein stabilizes and activates estrogen receptor alpha.
Molecular cell 2006;21(2):295-305.
2006: Ren J; Bharti A; Raina D; Chen W; Ahmad R; Kufe D
MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90.
Oncogene 2006;25(1):20-31.
2006: Mezhir J J; Smith K D; Posner M C; Senzer N; Yamini B; Kufe D W; Weichselbaum R R
Ionizing radiation: a genetic switch for cancer therapy.
Cancer gene therapy 2006;13(1):1-6.
2005: Agata Naoki; Nogi Hiroko; Bamberg Michael; Milhollen Michael; Pu Minying; Weitman Steven; Kharbanda Surender; Kufe Donald
The angiogenesis inhibitor NM-3 is active against human NSCLC xenografts alone and in combination with docetaxel.
Cancer chemotherapy and pharmacology 2005;56(6):610-4.
2005: Huang Lei; Chen Dongshu; Liu Derek; Yin Li; Kharbanda Surender; Kufe Donald
MUC1 oncoprotein blocks glycogen synthase kinase 3beta-mediated phosphorylation and degradation of beta-catenin.
Cancer research 2005;65(22):10413-22.
2005: Mezhir James J; Schmidt Hank; Yamini Bakhtiar; Senzer Neil N; Posner Mitchell C; Kufe Donald W; Weichselbaum Ralph R
Chemo-inducible gene therapy.
Anti-cancer drugs 2005;16(10):1053-8.
2005: Murphy Kevin T; Wardak Abdullah; Beckett Michael A; Lopez Carlos A; Mehta Neil; Kimchi Eric; Salloum Rabih M; Jaskowiak Nora T; Posner Mitchell C; Ohno Tsuneya; Kufe Donald W; Weichselbaum Ralph R; Mauceri Helena J
Forphenicinol enhances the antitumor effects of cyclophosphamide in a model of squamous cell carcinoma.
Cancer chemotherapy and pharmacology 2005;56(3):317-21.
2005: Vasir Baldev; Borges Virginia; Wu Zekui; Grosman Daren; Rosenblatt Jacalyn; Irie Masaki; Anderson Kenneth; Kufe Donald; Avigan David
Fusion of dendritic cells with multiple myeloma cells results in maturation and enhanced antigen presentation.
British journal of haematology 2005;129(5):687-700.
2005: Rosenblatt Jacalyn; Kufe Donald; Avigan David
Dendritic cell fusion vaccines for cancer immunotherapy.
Expert opinion on biological therapy 2005;5(5):703-15.
2005: Ikeda T; Kimura F; Nakata Y; Sato K; Ogura K; Motoyoshi K; Sporn M; Kufe D
Triterpenoid CDDO-Im downregulates PML/RARalpha expression in acute promyelocytic leukemia cells.
Cell death and differentiation 2005;12(5):523-31.
2005: Homma S; Kikuchi T; Ishiji N; Ochiai K; Takeyama H; Saotome H; Sagawa Y; Hara E; Kufe D; Ryan J L; Ohno T; Toda G
Cancer immunotherapy by fusions of dendritic and tumour cells and rh-IL-12.
European journal of clinical investigation 2005;35(4):279-86.
2005: Cao Cheng; Li Yanping; Leng Yumei; Li Ping; Ma Qingjun; Kufe Donald
Ubiquitination and degradation of the Arg tyrosine kinase is regulated by oxidative stress.
Oncogene 2005;24(15):2433-40.
2005: Yoshida Kiyotsugu; Yamaguchi Tomoko; Natsume Tohru; Kufe Donald; Miki Yoshio
JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage.
Nature cell biology 2005;7(3):278-85.
2005: Raina Deepak; Pandey Pramod; Ahmad Rehan; Bharti Ajit; Ren Jian; Kharbanda Surender; Weichselbaum Ralph; Kufe Donald
c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage.
The Journal of biological chemistry 2005;280(12):11147-51.
2005: Wei Xiaolong; Xu Hai; Kufe Donald
Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response.
Cancer cell 2005;7(2):167-78.
2005: Vasir Baldev; Avigan David; Wu Zekui; Crawford Keith; Turnquist Shawn; Ren Jian; Kufe Donald
Dendritic cells induce MUC1 expression and polarization on human T cells by an IL-7-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(4):2376-86.
2004: Agata Naoki; Nogi Hiroko; Milhollen Michael; Kharbanda Surender; Kufe Donald
2-(8-Hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl)propionic acid, a small molecule isocoumarin, potentiates dexamethasone-induced apoptosis of human multiple myeloma cells.
Cancer research 2004;64(23):8512-6.
2004: Gong Jianlin; Koido Shigeo; Kato Yoko; Tanaka Yasuhiro; Chen Dongshu; Jonas Anna; Galinsky Ilene; DeAngelo Daniel; Avigan David; Kufe Donald; Stone Richard
Induction of anti-leukemic cytotoxic T lymphocytes by fusion of patient-derived dendritic cells with autologous myeloblasts.
Leukemia research 2004;28(12):1303-12.
2004: Kikuchi Tetsuro; Akasaki Yasuharu; Abe Toshiaki; Fukuda Takahiro; Saotome Hideo; Ryan John L; Kufe Donald W; Ohno Tsuneya
Vaccination of glioma patients with fusions of dendritic and glioma cells and recombinant human interleukin 12.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2004;27(6):452-9.
2004: Yin Li; Huang Lei; Kufe Donald
MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress.
The Journal of biological chemistry 2004;279(44):45721-7.
2004: Yamini Bakhtiar; Yu Xiaohong; Gillespie G Yancey; Kufe Donald W; Weichselbaum Ralph R
Transcriptional targeting of adenovirally delivered tumor necrosis factor alpha by temozolomide in experimental glioblastoma.
Cancer research 2004;64(18):6381-4.
2004: Lopez Carlos A; Kimchi Eric T; Mauceri Helena J; Park James O; Mehta Neil; Murphy Kevin T; Beckett Michael A; Hellman Samuel; Posner Mitchell C; Kufe Donald W; Weichselbaum Ralph R
Chemoinducible gene therapy: a strategy to enhance doxorubicin antitumor activity.
Molecular cancer therapeutics 2004;3(9):1167-75.
2004: Mundt Arno J; Vijayakumar Srinivasan; Nemunaitis John; Sandler Alan; Schwartz Herbert; Hanna Nader; Peabody Terrence; Senzer Neil; Chu Karen; Rasmussen Camilla S; Kessler Paul D; Rasmussen Henrik S; Warso Michael; Kufe Donald W; Gupta Tapas Das; Weichselbaum Ralph R
A Phase I trial of TNFerade biologic in patients with soft tissue sarcoma in the extremities.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(17):5747-53.
2004: Irie Masaki; Homma Sadamu; Komita Hideo; Zeniya Mikio; Kufe Donald; Ohno Tsuneya; Toda Gotaro
Inhibition of spontaneous development of liver tumors by inoculation with dendritic cells loaded with hepatocellular carcinoma cells in C3H/HeNCRJ mice.
International journal of cancer. Journal international du cancer 2004;111(2):238-45.
2004: Nakamura Motoyuki; Kikuchi Tetsuro; Kufe Donald W; Ohno Tsuneya
Antitumor effects of fusions composed of dendritic cells and fibroblasts transfected with genomic DNA from tumor cells.
Cancer immunology, immunotherapy : CII 2004;53(8):690-6.
2004: Avigan David; Vasir Baldev; Gong Jianlin; Borges Virginia; Wu Zekui; Uhl Lynne; Atkins Michael; Mier James; McDermott David; Smith Therese; Giallambardo Nancy; Stone Carolyn; Schadt Kim; Dolgoff Jennifer; Tetreault Jean-Claude; Villarroel Marisa; Kufe Donald
Fusion cell vaccination of patients with metastatic breast and renal cancer induces immunological and clinical responses.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(14):4699-708.
2004: Iinuma Toshio; Homma Sadamu; Noda Tetsuo; Kufe Donald; Ohno Tsuneya; Toda Gotaro
Prevention of gastrointestinal tumors based on adenomatous polyposis coli gene mutation by dendritic cell vaccine.
The Journal of clinical investigation 2004;113(9):1307-17.
2004: Raje Noopur; Hideshima Teru; Davies Faith E; Chauhan Dharminder; Treon Steven P; Young Gloria; Tai Yu-Tzu; Avigan David; Gong Jianlin; Schlossman Robert L; Richardson Paul; Kufe Donald W; Anderson Kenneth C
Tumour cell/dendritic cell fusions as a vaccination strategy for multiple myeloma.
British journal of haematology 2004;125(3):343-52.
2004: Raina Deepak; Kharbanda Surender; Kufe Donald
The MUC1 oncoprotein activates the anti-apoptotic phosphoinositide 3-kinase/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts.
The Journal of biological chemistry 2004;279(20):20607-12.
2004: Li Quan; Ren Jian; Kufe Donald
Interaction of human MUC1 and beta-catenin is regulated by Lck and ZAP-70 in activated Jurkat T cells.
Biochemical and biophysical research communications 2004;315(2):471-6.
2004: Ren Jian; Agata Naoki; Chen Dongshu; Li Yongqing; Yu Wei-hsuan; Huang Lei; Raina Deepak; Chen Wen; Kharbanda Surender; Kufe Donald
Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents.
Cancer cell 2004;5(2):163-75.
2004: Senzer Neil; Mani Sridhar; Rosemurgy Alexander; Nemunaitis John; Cunningham Casey; Guha Chandan; Bayol Natalia; Gillen Michelle; Chu Karen; Rasmussen Camilla; Rasmussen Henrik; Kufe Donald; Weichselbaum Ralph; Hanna Nader
TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: a phase I study in patients with solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(4):592-601.
2004: Ikeda Takashi; Nakata Yukiko; Kimura Fumihiko; Sato Ken; Anderson Kenneth; Motoyoshi Kazuo; Sporn Michael; Kufe Donald
Induction of redox imbalance and apoptosis in multiple myeloma cells by the novel triterpenoid 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid.
Molecular cancer therapeutics 2004;3(1):39-45.
2003: Huang Lei; Ren Jian; Chen Dongshu; Li Yongqing; Kharbanda Surender; Kufe Donald
MUC1 cytoplasmic domain coactivates Wnt target gene transcription and confers transformation.
Cancer biology & therapy 2003;2(6):702-6.
2003: Supko Jeffrey G; Eder Joseph P; Ryan David P; Seiden Michael V; Lynch Thomas J; Amrein Phillip C; Kufe Donald W; Clark Jeffrey W
Phase I clinical trial and pharmacokinetic study of the spicamycin analog KRN5500 administered as a 1-hour intravenous infusion for five consecutive days to patients with refractory solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(14):5178-86.
2003: Takeda A; Homma S; Okamoto T; Kufe D; Ohno T
Immature dendritic cell/tumor cell fusions induce potent antitumour immunity.
European journal of clinical investigation 2003;33(10):897-904.
2003: Cao Cheng; Leng Yumei; Huang Wei; Liu Xuan; Kufe Donald
Glutathione peroxidase 1 is regulated by the c-Abl and Arg tyrosine kinases.
The Journal of biological chemistry 2003;278(41):39609-14.
2003: Ikeda Takashi; Sporn Michael; Honda Tadashi; Gribble Gordon W; Kufe Donald
The novel triterpenoid CDDO and its derivatives induce apoptosis by disruption of intracellular redox balance.
Cancer research 2003;63(17):5551-8.
2003: Li Yongqing; Liu Derek; Chen Dongshu; Kharbanda Surender; Kufe Donald
Human DF3/MUC1 carcinoma-associated protein functions as an oncogene.
Oncogene 2003;22(38):6107-10.
2003: Cao Cheng; Leng Yumei; Liu Xuan; Yi Yanping; Li Ping; Kufe Donald
Catalase is regulated by ubiquitination and proteosomal degradation. Role of the c-Abl and Arg tyrosine kinases.
Biochemistry 2003;42(35):10348-53.
2003: Cheng Wen-Hsing; von Kobbe Cayetano; Opresko Patricia L; Fields Kesha M; Ren Jian; Kufe Donald; Bohr Vilhelm A
Werner syndrome protein phosphorylation by abl tyrosine kinase regulates its activity and distribution.
Molecular and cellular biology 2003;23(18):6385-95.
2003: Yin Li; Li Yongqing; Ren Jian; Kuwahara Hiroaki; Kufe Donald
Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress.
The Journal of biological chemistry 2003;278(37):35458-64.
2003: Li Yongqing; Yu Wei-Hsuan; Ren Jian; Chen Wen; Huang Lei; Kharbanda Surender; Loda Massimo; Kufe Donald
Heregulin targets gamma-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 oncoprotein.
Molecular cancer research : MCR 2003;1(10):765-75.
2003: Cao Cheng; Leng Yumei; Kufe Donald
Catalase activity is regulated by c-Abl and Arg in the oxidative stress response.
The Journal of biological chemistry 2003;278(32):29667-75.
2003: Kufe Donald; Weichselbaum Ralph
Radiation therapy: activation for gene transcription and the development of genetic radiotherapy-therapeutic strategies in oncology.
Cancer biology & therapy 2003;2(4):326-9.
2003: Chen Dongshu; Xia Jianchuan; Tanaka Yasuhiro; Chen Hongsong; Koido Shigeo; Wernet Oliver; Mukherjee Pinku; Gendler Sandra J; Kufe Donald; Gong Jianlin
Immunotherapy of spontaneous mammary carcinoma with fusions of dendritic cells and mucin 1-positive carcinoma cells.
Immunology 2003;109(2):300-7.
2003: Cao Cheng; Leng Yumei; Li Chufang; Kufe Donald
Functional interaction between the c-Abl and Arg protein-tyrosine kinases in the oxidative stress response.
The Journal of biological chemistry 2003;278(15):12961-7.
2003: Li Yongqing; Chen Wen; Ren Jian; Yu Wei-Hsuan; Li Quan; Yoshida Kiyotsugu; Kufe Donald
DF3/MUC1 signaling in multiple myeloma cells is regulated by interleukin-7.
Cancer biology & therapy 2003;2(2):187-93.
2003: Yoshida Kiyotsugu; Wang Hong-Gang; Miki Yoshio; Kufe Donald
Protein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9.
The EMBO journal 2003;22(6):1431-41.
2003: Gupta V K; Park J O; Kurihara T; Koons A; Mauceri H J; Jaskowiak N T; Kufe D W; Weichselbaum R R; Posner M C
Selective gene expression using a DF3/MUC1 promoter in a human esophageal adenocarcinoma model.
Gene therapy 2003;10(3):206-12.
2003: Kumar Shailendra; Mishra Neerad; Raina Deepak; Saxena Satya; Kufe Donald
Abrogation of the cell death response to oxidative stress by the c-Abl tyrosine kinase inhibitor STI571.
Molecular pharmacology 2003;63(2):276-82.
2003: Homma Sadamu; Matai Kazuo; Irie Masaki; Ohno Tsuneya; Kufe Donald; Toda Gotaro
Immunotherapy using fusions of autologous dendritic cells and tumor cells showed effective clinical response in a patient with advanced gastric carcinoma.
Journal of gastroenterology 2003;38(10):989-94.
2002: Yoshida Kiyotsugu; Miki Yoshio; Kufe Donald
Activation of SAPK/JNK signaling by protein kinase Cdelta in response to DNA damage.
The Journal of biological chemistry 2002;277(50):48372-8.
2002: Borges Virginia F; Kufe Donald; Avigan David E
Update on cancer vaccines.
Current opinion in gastroenterology 2002;18(6):723-31.
2002: Ren Xinping; Cao Cheng; Zhu Liben; Yoshida Kiyotsugu; Kharbanda Surender; Weichselbaum Ralph; Kufe Donald
Lyn tyrosine kinase inhibits nuclear export of the p53 tumor suppressor.
Cancer biology & therapy 2002;1(6):703-8.
2002: Mauceri Helena J; Seetharam Saraswathy; Beckett Michael A; Schumm L Philip; Koons Ann; Gupta Vinay K; Park James O; Manan Abdullah; Lee John Y; Montag Anthony G; Kufe Donald W; Weichselbaum Ralph R
Angiostatin potentiates cyclophosphamide treatment of metastatic disease.
Cancer chemotherapy and pharmacology 2002;50(5):412-8.
2002: Weichselbaum Ralph R; Kufe Donald W; Hellman Samuel; Rasmussen Henrik S; King C Richter; Fischer Paul H; Mauceri Helena J
Radiation-induced tumour necrosis factor-alpha expression: clinical application of transcriptional and physical targeting of gene therapy.
The lancet oncology 2002;3(11):665-71.
2002: Eder Joseph P; Supko Jeffrey G; Clark Jeffrey W; Puchalski Thomas A; Garcia-Carbonero Rocio; Ryan David P; Shulman Lawrence N; Proper Joann; Kirvan Moira; Rattner Barbara; Connors Susan; Keogan Mary T; Janicek Milos J; Fogler William E; Schnipper Lowell; Kinchla Nancy; Sidor Carolyn; Phillips Eric; Folkman Judah; Kufe Donald W
Phase I clinical trial of recombinant human endostatin administered as a short intravenous infusion repeated daily.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(18):3772-84.
2002: Ren Jian; Datta Rakesh; Shioya Hisashi; Li Yongqing; Oki Eiji; Biedermann Verena; Bharti Ajit; Kufe Donald
p73beta is regulated by protein kinase Cdelta catalytic fragment generated in the apoptotic response to DNA damage.
The Journal of biological chemistry 2002;277(37):33758-65.
2002: Park James O; Lopez Carlos A; Gupta Vinay K; Brown Charles K; Mauceri Helena J; Darga Thomas E; Manan Abdullah; Hellman Samuel; Posner Mitchell C; Kufe Donald W; Weichselbaum Ralph R
Transcriptional control of viral gene therapy by cisplatin.
The Journal of clinical investigation 2002;110(3):403-10.
2002: Raina Deepak; Mishra Neerad; Kumar Shailendra; Kharbanda Surender; Saxena Satya; Kufe Donald
Inhibition of c-Abl with STI571 attenuates stress-activated protein kinase activation and apoptosis in the cellular response to 1-beta-D-arabinofuranosylcytosine.
Molecular pharmacology 2002;61(6):1489-95.
2002: Yoshida Kiyotsugu; Komatsu Kiyoshi; Wang Hong-Gang; Kufe Donald
c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage.
Molecular and cellular biology 2002;22(10):3292-300.
2002: Epperly Michael W; Sikora Christine A; DeFilippi Stacy J; Gretton Joan A; Zhan Qimin; Kufe Donald W; Greenberger Joel S
Manganese superoxide dismutase (SOD2) inhibits radiation-induced apoptosis by stabilization of the mitochondrial membrane.
Radiation research 2002;157(5):568-77.
2002: Ren Jian; Li Yongqing; Kufe Donald
Protein kinase C delta regulates function of the DF3/MUC1 carcinoma antigen in beta-catenin signaling.
The Journal of biological chemistry 2002;277(20):17616-22.
2002: Gong Jianlin; Koido Shigeo; Chen Dongshu; Tanaka Yasuhiro; Huang Lei; Avigan David; Anderson Kenneth; Ohno Tsuneya; Kufe Donald
Immunization against murine multiple myeloma with fusions of dendritic and plasmacytoma cells is potentiated by interleukin 12.
Blood 2002;99(7):2512-7.
2002: Koido Shigeo; Tanaka Yasuhiro; Chen Dongshu; Kufe Donald; Gong Jianlin
The kinetics of in vivo priming of CD4 and CD8 T cells by dendritic/tumor fusion cells in MUC1-transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(5):2111-7.
2002: Reimer Corinne L; Agata Naoki; Tammam Jennifer G; Bamberg Michael; Dickerson William M; Kamphaus George D; Rook Susan L; Milhollen Michael; Fram Robert; Kalluri Raghu; Kufe Donald; Kharbanda Surender
Antineoplastic effects of chemotherapeutic agents are potentiated by NM-3, an inhibitor of angiogenesis.
Cancer research 2002;62(3):789-95.
2002: Mauceri Helena J; Seetharam Saraswathy; Beckett Michael A; Lee John Y; Gupta Vinay K; Gately Stephen; Stack M Sharon; Brown Charles K; Swedberg Kirsten; Kufe Donald W; Weichselbaum Ralph R
Tumor production of angiostatin is enhanced after exposure to TNF-alpha.
International journal of cancer. Journal international du cancer 2002;97(4):410-5.
2002: Gupta Vinay K; Jaskowiak Nora T; Beckett Michael A; Mauceri Helena J; Grunstein Jeremy; Johnson Randall S; Calvin Douglas A; Nodzenski Edwardine; Pejovic Marija; Kufe Donald W; Posner Mitchell C; Weichselbaum Ralph R
Vascular endothelial growth factor enhances endothelial cell survival and tumor radioresistance.
Cancer journal (Sudbury, Mass.) 2002;8(1):47-54.
2001: Yoshida K; Kufe D
Negative regulation of the SHPTP1 protein tyrosine phosphatase by protein kinase C delta in response to DNA damage.
Molecular pharmacology 2001;60(6):1431-8.
2001: Yin L; Ohno T; Weichselbaum R; Kharbanda S; Kufe D
The novel isocoumarin 2-(8-hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl) propionic acid (NM-3) induces lethality of human carcinoma cells by generation of reactive oxygen species.
Molecular cancer therapeutics 2001;1(1):43-8.
2001: Bunnell C A; Supko J G; Eder J P; Clark J W; Lynch T J; Kufe D W; Shulman L N
Phase I clinical trial of 7-cyanoquinocarcinol (DX-52-1) in adult patients with refractory solid malignancies.
Cancer chemotherapy and pharmacology 2001;48(5):347-55.
2001: Homma S; Toda G; Gong J; Kufe D; Ohno T
Preventive antitumor activity against hepatocellular carcinoma (HCC) induced by immunization with fusions of dendritic cells and HCC cells in mice.
Journal of gastroenterology 2001;36(11):764-71.
2001: Tanaka Y; Koido S; Chen D; Gendler S J; Kufe D; Gong J
Vaccination with allogeneic dendritic cells fused to carcinoma cells induces antitumor immunity in MUC1 transgenic mice.
Clinical immunology (Orlando, Fla.) 2001;101(2):192-200.
2001: Chmura S J; Gupta N; Advani S J; Kufe D W; Weichselbaum R R
Prospects for viral-based strategies enhancing the anti-tumor effects of ionizing radiation.
Seminars in radiation oncology 2001;11(4):338-45.
2001: Majumder P K; Mishra N C; Sun X; Bharti A; Kharbanda S; Saxena S; Kufe D
Targeting of protein kinase C delta to mitochondria in the oxidative stress response.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2001;12(9):465-70.
2001: Ito Y; Pandey P; Mishra N; Kumar S; Narula N; Kharbanda S; Saxena S; Kufe D
Targeting of the c-Abl tyrosine kinase to mitochondria in endoplasmic reticulum stress-induced apoptosis.
Molecular and cellular biology 2001;21(18):6233-42.
2001: Li Y; Ren J; Yu W; Li Q; Kuwahara H; Yin L; Carraway K L; Kufe D
The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin.
The Journal of biological chemistry 2001;276(38):35239-42.
2001: Ito Y; Mishra N C; Yoshida K; Kharbanda S; Saxena S; Kufe D
Mitochondrial targeting of JNK/SAPK in the phorbol ester response of myeloid leukemia cells.
Cell death and differentiation 2001;8(8):794-800.
2001: Gupta N; Nodzenski E; Khodarev N N; Yu J; Khorasani L; Beckett M A; Kufe D W; Weichselbaum R R
Angiostatin effects on endothelial cells mediated by ceramide and RhoA.
EMBO reports 2001;2(6):536-40.
2001: Akewanlop C; Watanabe M; Singh B; Walker M; Kufe D W; Hayes D F
Phagocytosis of breast cancer cells mediated by anti-MUC-1 monoclonal antibody, DF3, and its bispecific antibody.
Cancer research 2001;61(10):4061-5.
2001: Kumar S; Bharti A; Mishra N C; Raina D; Kharbanda S; Saxena S; Kufe D
Targeting of the c-Abl tyrosine kinase to mitochondria in the necrotic cell death response to oxidative stress.
The Journal of biological chemistry 2001;276(20):17281-5.
2001: Ito Y; Pandey P; Sporn M B; Datta R; Kharbanda S; Kufe D
The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism.
Molecular pharmacology 2001;59(5):1094-9.
2001: Ito Y; Pandey P; Sathyanarayana P; Ling P; Rana A; Weichselbaum R; Tan T H; Kufe D; Kharbanda S
Interaction of hematopoietic progenitor kinase 1 and c-Abl tyrosine kinase in response to genotoxic stress.
The Journal of biological chemistry 2001;276(21):18130-8.
2001: Cao C; Ren X; Kharbanda S; Koleske A; Prasad K V; Kufe D
The ARG tyrosine kinase interacts with Siva-1 in the apoptotic response to oxidative stress.
The Journal of biological chemistry 2001;276(15):11465-8.
2001: Li Y; Kuwahara H; Ren J; Wen G; Kufe D
The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3 beta and beta-catenin.
The Journal of biological chemistry 2001;276(9):6061-4.
2001: Li Y; Kufe D
The Human DF3/MUC1 carcinoma-associated antigen signals nuclear localization of the catenin p120(ctn).
Biochemical and biophysical research communications 2001;281(2):440-3.
2001: Villalona-Calero M A; Eder J P; Toppmeyer D L; Allen L F; Fram R; Velagapudi R; Myers M; Amato A; Kagen-Hallet K; Razvillas B; Kufe D W; Von Hoff D D; Rowinsky E K
Phase I and pharmacokinetic study of LU79553, a DNA intercalating bisnaphthalimide, in patients with solid malignancies.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(3):857-69.
2001: Weichselbaum R R; Kufe D W; Advani S J; Roizman B
Molecular targeting of gene therapy and radiotherapy.
Acta oncologica (Stockholm, Sweden) 2001;40(6):735-8.
2000: Salloum R M; Jaskowiak N T; Mauceri H J; Seetharam S; Beckett M A; Koons A M; Hari D M; Gupta V K; Reimer C; Kalluri R; Posner M C; Hellman S; Kufe D W; Weichselbaum R R
NM-3, an isocoumarin, increases the antitumor effects of radiotherapy without toxicity.
Cancer research 2000;60(24):6958-63.
2000: Datta R; Yoshinaga K; Kaneki M; Pandey P; Kufe D
Phorbol ester-induced generation of reactive oxygen species is protein kinase cbeta -dependent and required for SAPK activation.
The Journal of biological chemistry 2000;275(52):41000-3.
2000: Gong J; Apostolopoulos V; Chen D; Chen H; Koido S; Gendler S J; McKenzie I F; Kufe D
Selection and characterization of MUC1-specific CD8+ T cells from MUC1 transgenic mice immunized with dendritic-carcinoma fusion cells.
Immunology 2000;101(3):316-24.
2000: Koido S; Kashiwaba M; Chen D; Gendler S; Kufe D; Gong J
Induction of antitumor immunity by vaccination of dendritic cells transfected with MUC1 RNA.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(10):5713-9.
2000: Datta R; Oki E; Endo K; Biedermann V; Ren J; Kufe D
XIAP regulates DNA damage-induced apoptosis downstream of caspase-9 cleavage.
The Journal of biological chemistry 2000;275(41):31733-8.
2000: Hanna N N; Seetharam S; Mauceri H J; Beckett M A; Jaskowiak N T; Salloum R M; Hari D; Dhanabal M; Ramchandran R; Kalluri R; Sukhatme V P; Kufe D W; Weichselbaum R R
Antitumor interaction of short-course endostatin and ionizing radiation.
Cancer journal (Sudbury, Mass.) 2000;6(5):287-93.
2000: Kurihara T; Brough D E; Kovesdi I; Kufe D W
Selectivity of a replication-competent adenovirus for human breast carcinoma cells expressing the MUC1 antigen.
The Journal of clinical investigation 2000;106(6):763-71.
2000: Pandey P; Nakazawa A; Ito Y; Datta R; Kharbanda S; Kufe D
Requirement for caspase activation in monocytic differentiation of myeloid leukemia cells.
Oncogene 2000;19(34):3941-7.
2000: Pandey P; Saleh A; Nakazawa A; Kumar S; Srinivasula S M; Kumar V; Weichselbaum R; Nalin C; Alnemri E S; Kufe D; Kharbanda S
Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90.
The EMBO journal 2000;19(16):4310-22.
2000: Gong J; Nikrui N; Chen D; Koido S; Wu Z; Tanaka Y; Cannistra S; Avigan D; Kufe D
Fusions of human ovarian carcinoma cells with autologous or allogeneic dendritic cells induce antitumor immunity.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(3):1705-11.
2000: Yoshida K; Weichselbaum R; Kharbanda S; Kufe D
Role for Lyn tyrosine kinase as a regulator of stress-activated protein kinase activity in response to DNA damage.
Molecular and cellular biology 2000;20(15):5370-80.
2000: Avigan D; Wu Z; Joyce R; Elias A; Richardson P; McDermott D; Levine J; Kennedy L; Giallombardo N; Hurley D; Gong J; Kufe D
Immune reconstitution following high-dose chemotherapy with stem cell rescue in patients with advanced breast cancer.
Bone marrow transplantation 2000;26(2):169-76.
2000: Kharbanda S; Pandey P; Yamauchi T; Kumar S; Kaneki M; Kumar V; Bharti A; Yuan Z M; Ghanem L; Rana A; Weichselbaum R; Johnson G; Kufe D
Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage.
Molecular and cellular biology 2000;20(14):4979-89.
2000: Majumder P K; Pandey P; Sun X; Cheng K; Datta R; Saxena S; Kharbanda S; Kufe D
Mitochondrial translocation of protein kinase C delta in phorbol ester-induced cytochrome c release and apoptosis.
The Journal of biological chemistry 2000;275(29):21793-6.
2000: Sun X; Majumder P; Shioya H; Wu F; Kumar S; Weichselbaum R; Kharbanda S; Kufe D
Activation of the cytoplasmic c-Abl tyrosine kinase by reactive oxygen species.
The Journal of biological chemistry 2000;275(23):17237-40.
2000: Endo K; Oki E; Biedermann V; Kojima H; Yoshida K; Johannes F J; Kufe D; Datta R
Proteolytic cleavage and activation of protein kinase C [micro] by caspase-3 in the apoptotic response of cells to 1-beta -D-arabinofuranosylcytosine and other genotoxic agents.
The Journal of biological chemistry 2000;275(24):18476-81.
2000: Hari D; Beckett M A; Sukhatme V P; Dhanabal M; Nodzenski E; Lu H; Mauceri H J; Kufe D W; Weichselbaum R R
Angiostatin induces mitotic cell death of proliferating endothelial cells.
Molecular cell biology research communications : MCBRC 2000;3(5):277-82.
2000: Ito Y; Pandey P; Place A; Sporn M B; Gribble G W; Honda T; Kharbanda S; Kufe D
The novel triterpenoid 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid induces apoptosis of human myeloid leukemia cells by a caspase-8-dependent mechanism.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2000;11(5):261-7.
2000: Kharbanda S; Kumar V; Dhar S; Pandey P; Chen C; Majumder P; Yuan Z M; Whang Y; Strauss W; Pandita T K; Weaver D; Kufe D
Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase.
Current biology : CB 2000;10(10):568-75.
2000: Eder J P; Kantoff P W; Roper K; Xu G X; Bubley G J; Boyden J; Gritz L; Mazzara G; Oh W K; Arlen P; Tsang K Y; Panicali D; Schlom J; Kufe D W
A phase I trial of a recombinant vaccinia virus expressing prostate-specific antigen in advanced prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(5):1632-8.
2000: Colorado P C; Torre A; Kamphaus G; Maeshima Y; Hopfer H; Takahashi K; Volk R; Zamborsky E D; Herman S; Sarkar P K; Ericksen M B; Dhanabal M; Simons M; Post M; Kufe D W; Weichselbaum R R; Sukhatme V P; Kalluri R
Anti-angiogenic cues from vascular basement membrane collagen.
Cancer research 2000;60(9):2520-6.
2000: Pandey P; Farber R; Nakazawa A; Kumar S; Bharti A; Nalin C; Weichselbaum R; Kufe D; Kharbanda S
Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3.
Oncogene 2000;19(16):1975-81.
2000: Kumar V; Sabatini D; Pandey P; Gingras A C; Majumder P K; Kumar M; Yuan Z M; Carmichael G; Weichselbaum R; Sonenberg N; Kufe D; Kharbanda S
Regulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase.
The Journal of biological chemistry 2000;275(15):10779-87.
2000: Chmura S J; Nodzenski E; Kharbanda S; Pandey P; Quintans J; Kufe D W; Weichselbaum R R
Down-regulation of ceramide production abrogates ionizing radiation-induced cytochrome c release and apoptosis.
Molecular pharmacology 2000;57(4):792-6.
2000: Sun X; Wu F; Datta R; Kharbanda S; Kufe D
Interaction between protein kinase C delta and the c-Abl tyrosine kinase in the cellular response to oxidative stress.
The Journal of biological chemistry 2000;275(11):7470-3.
2000: Kufe D W
Smallpox, polio and now a cancer vaccine?
Nature medicine 2000;6(3):252-3.
2000: Kumar V; Pandey P; Sabatini D; Kumar M; Majumder P K; Bharti A; Carmichael G; Kufe D; Kharbanda S
Functional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translation.
The EMBO journal 2000;19(5):1087-97.
2000: Gong J; Avigan D; Chen D; Wu Z; Koido S; Kashiwaba M; Kufe D
Activation of antitumor cytotoxic T lymphocytes by fusions of human dendritic cells and breast carcinoma cells.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(6):2715-8.
2000: Chmura S J; Dolan M E; Cha A; Mauceri H J; Kufe D W; Weichselbaum R R
In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumor cell toxicity and growth delay in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(2):737-42.
2000: Kharbanda S; Saxena S; Yoshida K; Pandey P; Kaneki M; Wang Q; Cheng K; Chen Y N; Campbell A; Sudha T; Yuan Z M; Narula J; Weichselbaum R; Nalin C; Kufe D
Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage.
The Journal of biological chemistry 2000;275(1):322-7.
2000: Supko J G; Lynch T J; Clark J W; Fram R; Allen L F; Velagapudi R; Kufe D W; Eder J P
A phase I clinical and pharmacokinetic study of the dolastatin analogue cemadotin administered as a 5-day continuous intravenous infusion.
Cancer chemotherapy and pharmacology 2000;46(4):319-28.
1999: Yoshida K; Kharbanda S; Kufe D
Functional interaction between SHPTP1 and the Lyn tyrosine kinase in the apoptotic response to DNA damage.
The Journal of biological chemistry 1999;274(49):34663-8.
1999: Avigan D; Wu Z; Gong J; Joyce R; Levine J; Elias A; Richardson P; Milano J; Kennedy L; Anderson K; Kufe D
Selective in vivo mobilization with granulocyte macrophage colony-stimulating factor (GM-CSF)/granulocyte-CSF as compared to G-CSF alone of dendritic cell progenitors from peripheral blood progenitor cells in patients with advanced breast cancer undergoing autologous transplantation.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(10):2735-41.
1999: Yuan Z M; Huang Y; Ishiko T; Nakada S; Utsugisawa T; Shioya H; Utsugisawa Y; Shi Y; Weichselbaum R; Kufe D
Function for p300 and not CBP in the apoptotic response to DNA damage.
Oncogene 1999;18(41):5714-7.
1999: Seetharam S; Staba M J; Schumm L P; Schreiber K; Schreiber H; Kufe D W; Weichselbaum R R
Enhanced eradication of local and distant tumors by genetically produced interleukin-12 and radiation.
International journal of oncology 1999;15(4):769-73.
1999: Gorski D H; Beckett M A; Jaskowiak N T; Calvin D P; Mauceri H J; Salloum R M; Seetharam S; Koons A; Hari D M; Kufe D W; Weichselbaum R R
Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation.
Cancer research 1999;59(14):3374-8.
1999: Yuan Z M; Shioya H; Ishiko T; Sun X; Gu J; Huang Y Y; Lu H; Kharbanda S; Weichselbaum R; Kufe D
p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage.
Nature 1999;399(6738):814-7.
1999: Tai Y T; Strobel T; Kufe D; Cannistra S A
In vivo cytotoxicity of ovarian cancer cells through tumor-selective expression of the BAX gene.
Cancer research 1999;59(9):2121-6.
1999: Huang Y; Nakada S; Ishiko T; Utsugisawa T; Datta R; Kharbanda S; Yoshida K; Talanian R V; Weichselbaum R; Kufe D; Yuan Z M
Role for caspase-mediated cleavage of Rad51 in induction of apoptosis by DNA damage.
Molecular and cellular biology 1999;19(4):2986-97.
1999: Raje N; Gong J; Chauhan D; Teoh G; Avigan D; Wu Z; Chen D; Treon S P; Webb I J; Kufe D W; Anderson K C
Bone marrow and peripheral blood dendritic cells from patients with multiple myeloma are phenotypically and functionally normal despite the detection of Kaposi's sarcoma herpesvirus gene sequences.
Blood 1999;93(5):1487-95.
1999: Mauceri H J; Hanna N N; Staba M J; Beckett M A; Kufe D W; Weichselbaum R R
Radiation-inducible gene therapy.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1999;322(2-3):225-8.
1999: Guo X Y; Balague C; Wang T; Randhawa G; Yuan Z; Bachier C; Greenberger J; Arlinghaus R; Kufe D; Deisseroth A B
The presence of the Rb c-box peptide in the cytoplasm inhibits p210bcr-abl transforming function.
Oncogene 1999;18(8):1589-95.
1999: Yuan Z M; Huang Y; Ishiko T; Nakada S; Utsugisawa T; Shioya H; Utsugisawa Y; Yokoyama K; Weichselbaum R; Shi Y; Kufe D
Role for p300 in stabilization of p53 in the response to DNA damage.
The Journal of biological chemistry 1999;274(4):1883-6.
1999: Kaneki M; Kharbanda S; Pandey P; Yoshida K; Takekawa M; Liou J R; Stone R; Kufe D
Functional role for protein kinase Cbeta as a regulator of stress-activated protein kinase activation and monocytic differentiation of myeloid leukemia cells.
Molecular and cellular biology 1999;19(1):461-70.
1999: Chmura S J; Advani S J; Kufe D W; Weichselbaum R R
Strategies for enhancing viral-based gene therapy using ionizing radiation.
Radiation oncology investigations 1999;7(5):261-9.
1998: Kharbanda S; Yuan Z M; Weichselbaum R; Kufe D
Determination of cell fate by c-Abl activation in the response to DNA damage.
Oncogene 1998;17(25):3309-18.
1998: Gorski D H; Mauceri H J; Salloum R M; Gately S; Hellman S; Beckett M A; Sukhatme V P; Soff G A; Kufe D W; Weichselbaum R R
Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin.
Cancer research 1998;58(24):5686-9.
1998: Teoh G; Chen L; Urashima M; Tai Y T; Celi L A; Chen D; Chauhan D; Ogata A; Finberg R W; Webb I J; Kufe D W; Anderson K C
Adenovirus vector-based purging of multiple myeloma cells.
Blood 1998;92(12):4591-601.
1998: Li Y; Bharti A; Chen D; Gong J; Kufe D
Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-catenin.
Molecular and cellular biology 1998;18(12):7216-24.
1998: Chung T D; Mauceri H J; Hallahan D E; Yu J J; Chung S; Grdina W L; Yajnik S; Kufe D W; Weichselbaum R R
Tumor necrosis factor-alpha-based gene therapy enhances radiation cytotoxicity in human prostate cancer.
Cancer gene therapy 1998;5(6):344-9.
1998: Bharti A; Kraeft S K; Gounder M; Pandey P; Jin S; Yuan Z M; Lees-Miller S P; Weichselbaum R; Weaver D; Chen L B; Kufe D; Kharbanda S
Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis.
Molecular and cellular biology 1998;18(11):6719-28.
1998: Cristofanilli M; Bryan W J; Miller L L; Chang A Y; Gradishar W J; Kufe D W; Hortobagyi G N
Phase II study of adozelesin in untreated metastatic breast cancer.
Anti-cancer drugs 1998;9(9):779-82.
1998: Liedtke M; Pandey P; Kumar S; Kharbanda S; Kufe D
Regulation of Bcr-Abl-induced SAP kinase activity and transformation by the SHPTP1 protein tyrosine phosphatase.
Oncogene 1998;17(15):1889-92.
1998: Kumar S; Pandey P; Bharti A; Jin S; Weichselbaum R; Weaver D; Kufe D; Kharbanda S
Regulation of DNA-dependent protein kinase by the Lyn tyrosine kinase.
The Journal of biological chemistry 1998;273(40):25654-8.
1998: Seetharam S; Nodzenski E; Beckett M A; Heimann R; Cha A; Margulies I; Pastan I; Kufe D W; Weichselbaum R R
Modulation of apoptotic response of a radiation-resistant human carcinoma by Pseudomonas exotoxin-chimeric protein.
Cancer research 1998;58(15):3215-20.
1998: Guo X Y; Fontana J; Kufe D; Deisseroth A
Antagonistic effects of ABL and BCRABL proteins on proliferation and the response to genotoxic stress in normal and leukemic myeloid cells.
Leukemia & lymphoma 1998;30(3-4):225-35.
1998: Mauceri H J; Hanna N N; Beckett M A; Gorski D H; Staba M J; Stellato K A; Bigelow K; Heimann R; Gately S; Dhanabal M; Soff G A; Sukhatme V P; Kufe D W; Weichselbaum R R
Combined effects of angiostatin and ionizing radiation in antitumour therapy.
Nature 1998;394(6690):287-91.
1998: Manome Y; Kunieda T; Wen P Y; Koga T; Kufe D W; Ohno T
Transgene expression in malignant glioma using a replication-defective adenoviral vector containing the Egr-1 promoter: activation by ionizing radiation or uptake of radioactive iododeoxyuridine.
Human gene therapy 1998;9(10):1409-17.
1998: Kojima H; Endo K; Moriyama H; Tanaka Y; Alnemri E S; Slapak C A; Teicher B; Kufe D; Datta R
Abrogation of mitochondrial cytochrome c release and caspase-3 activation in acquired multidrug resistance.
The Journal of biological chemistry 1998;273(27):16647-50.
1998: Gong J; Chen D; Kashiwaba M; Li Y; Chen L; Takeuchi H; Qu H; Rowse G J; Gendler S J; Kufe D
Reversal of tolerance to human MUC1 antigen in MUC1 transgenic mice immunized with fusions of dendritic and carcinoma cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(11):6279-83.
1998: Kharbanda S; Pandey P; Morris P L; Whang Y; Xu Y; Sawant S; Zhu L J; Kumar N; Yuan Z M; Weichselbaum R; Sawyers C L; Pandita T K; Kufe D
Functional role for the c-Abl tyrosine kinase in meiosis I.
Oncogene 1998;16(14):1773-7.
1998: Yuan Z M; Utsugisawa T; Ishiko T; Nakada S; Huang Y; Kharbanda S; Weichselbaum R; Kufe D
Activation of protein kinase C delta by the c-Abl tyrosine kinase in response to ionizing radiation.
Oncogene 1998;16(13):1643-8.
1998: Staba M J; Mauceri H J; Kufe D W; Hallahan D E; Weichselbaum R R
Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft.
Gene therapy 1998;5(3):293-300.
1998: Eder J P; Supko J G; Lynch T; Bryant M; Vosburgh E; Shulman L N; Xu G; Kufe D W
Phase I trial of the colloidal dispersion formulation of 9-amino-20(S)-camptothecin administered as a 72-hour continuous intravenous infusion.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(2):317-24.
1998: Yuan Z M; Huang Y; Ishiko T; Nakada S; Utsugisawa T; Kharbanda S; Wang R; Sung P; Shinohara A; Weichselbaum R; Kufe D
Regulation of Rad51 function by c-Abl in response to DNA damage.
The Journal of biological chemistry 1998;273(7):3799-802.
1997: Chauhan D; Pandey P; Ogata A; Teoh G; Krett N; Halgren R; Rosen S; Kufe D; Kharbanda S; Anderson K
Cytochrome c-dependent and -independent induction of apoptosis in multiple myeloma cells.
The Journal of biological chemistry 1997;272(48):29995-7.
1997: Gong J; Chen L; Chen D; Kashiwaba M; Manome Y; Tanaka T; Kufe D
Induction of antigen-specific antitumor immunity with adenovirus-transduced dendritic cells.
Gene therapy 1997;4(10):1023-8.
1997: Kharbanda S; Yuan Z M; Weichselbaum R; Kufe D
Functional role for the c-Abl protein tyrosine kinase in the cellular response to genotoxic stress.
Biochimica et biophysica acta 1997;1333(2):O1-7.
1997: Huang Y; Yuan Z M; Ishiko T; Nakada S; Utsugisawa T; Kato T; Kharbanda S; Kufe D W
Pro-apoptotic effect of the c-Abl tyrosine kinase in the cellular response to 1-beta-D-arabinofuranosylcytosine.
Oncogene 1997;15(16):1947-52.
1997: Parr M J; Manome Y; Tanaka T; Wen P; Kufe D W; Kaelin W G; Fine H A
Tumor-selective transgene expression in vivo mediated by an E2F-responsive adenoviral vector.
Nature medicine 1997;3(10):1145-9.
1997: Chmura S J; Mauceri H J; Advani S; Heimann R; Beckett M A; Nodzenski E; Quintans J; Kufe D W; Weichselbaum R R
Decreasing the apoptotic threshold of tumor cells through protein kinase C inhibition and sphingomyelinase activation increases tumor killing by ionizing radiation.
Cancer research 1997;57(19):4340-7.
1997: Hanna N N; Mauceri H J; Wayne J D; Hallahan D E; Kufe D W; Weichselbaum R R
Virally directed cytosine deaminase/5-fluorocytosine gene therapy enhances radiation response in human cancer xenografts.
Cancer research 1997;57(19):4205-9.
1997: Jin S; Kharbanda S; Mayer B; Kufe D; Weaver D T
Binding of Ku and c-Abl at the kinase homology region of DNA-dependent protein kinase catalytic subunit.
The Journal of biological chemistry 1997;272(40):24763-6.
1997: Yuan Z M; Utsugisawa T; Huang Y; Ishiko T; Nakada S; Kharbanda S; Weichselbaum R; Kufe D
Inhibition of phosphatidylinositol 3-kinase by c-Abl in the genotoxic stress response.
The Journal of biological chemistry 1997;272(38):23485-8.
1997: Datta R; Kojima H; Yoshida K; Kufe D
Caspase-3-mediated cleavage of protein kinase C theta in induction of apoptosis.
The Journal of biological chemistry 1997;272(33):20317-20.
1997: Chen L; Chen D; Block E; O'Donnell M; Kufe D W; Clinton S K
Eradication of murine bladder carcinoma by intratumor injection of a bicistronic adenoviral vector carrying cDNAs for the IL-12 heterodimer and its inhibition by the IL-12 p40 subunit homodimer.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(1):351-9.
1997: Kharbanda S; Pandey P; Schofield L; Israels S; Roncinske R; Yoshida K; Bharti A; Yuan Z M; Saxena S; Weichselbaum R; Nalin C; Kufe D
Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(13):6939-42.
1997: Shafman T; Khanna K K; Kedar P; Spring K; Kozlov S; Yen T; Hobson K; Gatei M; Zhang N; Watters D; Egerton M; Shiloh Y; Kharbanda S; Kufe D; Lavin M F
Interaction between ATM protein and c-Abl in response to DNA damage.
Nature 1997;387(6632):520-3.
1997: Weichselbaum R R; Kufe D
Gene therapy of cancer.
Lancet 1997;349 Suppl 2():SII10-2.
1997: Gong J; Chen D; Kashiwaba M; Kufe D
Induction of antitumor activity by immunization with fusions of dendritic and carcinoma cells.
Nature medicine 1997;3(5):558-61.
1997: Yamamoto M; Bharti A; Li Y; Kufe D
Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion.
The Journal of biological chemistry 1997;272(19):12492-4.
1997: Tsuji K; Uwano T; Yoshida Y; Kikuchi K; Okamoto T; Yamamoto S; Ichiki M; Hayashi I; Ohno T; Kufe D W
Detection of the circulating lung cancer marker LCAP with a new monoclonal antibody TRD-L1.
The International journal of biological markers 1997;12(2):49-54.
1997: Li X G; Haluska P; Hsiang Y H; Bharti A K; Kufe D W; Liu L F; Rubin E H
Involvement of amino acids 361 to 364 of human topoisomerase I in camptothecin resistance and enzyme catalysis.
Biochemical pharmacology 1997;53(7):1019-27.
1997: Kharbanda S; Pandey P; Jin S; Inoue S; Bharti A; Yuan Z M; Weichselbaum R; Weaver D; Kufe D
Functional interaction between DNA-PK and c-Abl in response to DNA damage.
Nature 1997;386(6626):732-5.
1997: Chmura S J; Nodzenski E; Beckett M A; Kufe D W; Quintans J; Weichselbaum R R
Loss of ceramide production confers resistance to radiation-induced apoptosis.
Cancer research 1997;57(7):1270-5.
1997: Tanaka T; Manome Y; Wen P; Kufe D W; Fine H A
Viral vector-mediated transduction of a modified platelet factor 4 cDNA inhibits angiogenesis and tumor growth.
Nature medicine 1997;3(4):437-42.
1997: Yuan Z M; Huang Y; Ishiko T; Kharbanda S; Weichselbaum R; Kufe D
Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(4):1437-40.
1997: Akagi J; Hodge J W; McLaughlin J P; Gritz L; Mazzara G; Kufe D; Schlom J; Kantor J A
Therapeutic antitumor response after immunization with an admixture of recombinant vaccinia viruses expressing a modified MUC1 gene and the murine T-cell costimulatory molecule B7.
Journal of immunotherapy (Hagerstown, Md. : 1997) 1997;20(1):38-47.
1997: Datta R; Kojima H; Banach D; Bump N J; Talanian R V; Alnemri E S; Weichselbaum R R; Wong W W; Kufe D W
Activation of a CrmA-insensitive, p35-sensitive pathway in ionizing radiation-induced apoptosis.
The Journal of biological chemistry 1997;272(3):1965-9.
1997: Chauhan D; Kharbanda S; Ogata A; Urashima M; Teoh G; Robertson M; Kufe D W; Anderson K C
Interleukin-6 inhibits Fas-induced apoptosis and stress-activated protein kinase activation in multiple myeloma cells.
Blood 1997;89(1):227-34.
1996: Eder J P; Rubin E; Stone R; Bryant M; Xu G; Supko J; Kinchla N; Lynch T; Hurwitz S; Rodriguez D; Shapiro C; Toppmeyer D; Grossbard M; Vosburg E; Huberman M; Schnipper L; Shulman L; Kufe D W
Trials of 9-amino-20(S)-camptothecin in Boston.
Annals of the New York Academy of Sciences 1996;803():247-55.
1996: Li X G; Haluska P; Hsiang Y H; Bharti A; Kufe D W; Rubin E H
Identification of topoisomerase I mutations affecting both DNA cleavage and interaction with camptothecin.
Annals of the New York Academy of Sciences 1996;803():111-27.
1996: Ghayur T; Hugunin M; Talanian R V; Ratnofsky S; Quinlan C; Emoto Y; Pandey P; Datta R; Huang Y; Kharbanda S; Allen H; Kamen R; Wong W; Kufe D
Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis.
The Journal of experimental medicine 1996;184(6):2399-404.
1996: Chen L; Pulsipher M; Chen D; Sieff C; Elias A; Fine H A; Kufe D W
Selective transgene expression for detection and elimination of contaminating carcinoma cells in hematopoietic stem cell sources.
The Journal of clinical investigation 1996;98(11):2539-48.
1996: Gimmi C D; Morrison B W; Mainprice B A; Gribben J G; Boussiotis V A; Freeman G J; Park S Y; Watanabe M; Gong J; Hayes D F; Kufe D W; Nadler L M
Breast cancer-associated antigen, DF3/MUC1, induces apoptosis of activated human T cells.
Nature medicine 1996;2(12):1367-70.
1996: Yuan Z M; Huang Y; Fan M M; Sawyers C; Kharbanda S; Kufe D
Genotoxic drugs induce interaction of the c-Abl tyrosine kinase and the tumor suppressor protein p53.
The Journal of biological chemistry 1996;271(43):26457-60.
1996: Datta R; Banach D; Kojima H; Talanian R V; Alnemri E S; Wong W W; Kufe D W
Activation of the CPP32 protease in apoptosis induced by 1-beta-D-arabinofuranosylcytosine and other DNA-damaging agents.
Blood 1996;88(6):1936-43.
1996: Yuan Z M; Huang Y; Kraeft S K; Chen L B; Kharbanda S; Kufe D
Interaction of cyclin-dependent kinase 2 and the Lyn tyrosine kinase in cells treated with 1-beta-D-arabinofuranosylcytosine.
Oncogene 1996;13(5):939-46.
1996: Pandey P; Raingeaud J; Kaneki M; Weichselbaum R; Davis R J; Kufe D; Kharbanda S
Activation of p38 mitogen-activated protein kinase by c-Abl-dependent and -independent mechanisms.
The Journal of biological chemistry 1996;271(39):23775-9.
1996: Kharbanda S; Saleem A; Yuan Z M; Kraeft S; Weichselbaum R; Chen L B; Kufe D
Nuclear signaling induced by ionizing radiation involves colocalization of the activated p56/p53lyn tyrosine kinase with p34cdc2.
Cancer research 1996;56(16):3617-21.
1996: Yuan Z M; Huang Y; Whang Y; Sawyers C; Weichselbaum R; Kharbanda S; Kufe D
Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.
Nature 1996;382(6588):272-4.
1996: Kharbanda S; Bharti A; Pei D; Wang J; Pandey P; Ren R; Weichselbaum R; Walsh C T; Kufe D
The stress response to ionizing radiation involoves c-Abl-dependent phosphorylation of SHPTP1.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(14):6898-901.
1996: Manome Y; Wen P Y; Chen L; Tanaka T; Dong Y; Yamazoe M; Hirshowitz A; Kufe D W; Fine H A
Gene therapy for malignant gliomas using replication incompetent retroviral and adenoviral vectors encoding the cytochrome P450 2B1 gene together with cyclophosphamide.
Gene therapy 1996;3(6):513-20.
1996: Manome Y; Wen P Y; Dong Y; Tanaka T; Mitchell B S; Kufe D W; Fine H A
Viral vector transduction of the human deoxycytidine kinase cDNA sensitizes glioma cells to the cytotoxic effects of cytosine arabinoside in vitro and in vivo.
Nature medicine 1996;2(5):567-73.
1996: Dong Y; Wen P; Manome Y; Parr M; Hirshowitz A; Chen L; Hirschowitz E A; Crystal R; Weichselbaum R; Kufe D W; Fine H A
In vivo replication-deficient adenovirus vector-mediated transduction of the cytosine deaminase gene sensitizes glioma cells to 5-fluorocytosine.
Human gene therapy 1996;7(6):713-20.
1996: Chen L; Waxman D J; Chen D; Kufe D W
Sensitization of human breast cancer cells to cyclophosphamide and ifosfamide by transfer of a liver cytochrome P450 gene.
Cancer research 1996;56(6):1331-40.
1996: Emoto Y; Kisaki H; Manome Y; Kharbanda S; Kufe D
Activation of protein kinase Cdelta in human myeloid leukemia cells treated with 1-beta-D-arabinofuranosylcytosine.
Blood 1996;87(5):1990-6.
1996: Manome Y; Yao X J; Kufe D W; Cohen E A; Fine H A
Selective effects of DNA damaging agents on HIV long terminal repeat activation and virus replication in vitro.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1996;11(2):109-16.
1996: Bharti A K; Olson M O; Kufe D W; Rubin E H
Identification of a nucleolin binding site in human topoisomerase I.
The Journal of biological chemistry 1996;271(4):1993-7.
1995: Saleem A; Datta R; Yuan Z M; Kharbanda S; Kufe D
Involvement of stress-activated protein kinase in the cellular response to 1-beta-D-arabinofuranosylcytosine and other DNA-damaging agents.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1995;6(12):1651-8.
1995: Chen L; Chen D; Manome Y; Dong Y; Fine H A; Kufe D W
Breast cancer selective gene expression and therapy mediated by recombinant adenoviruses containing the DF3/MUC1 promoter.
The Journal of clinical investigation 1995;96(6):2775-82.
1995: Hallahan D E; Dunphy E; Virudachalam S; Sukhatme V P; Kufe D W; Weichselbaum R R
C-jun and Egr-1 participate in DNA synthesis and cell survival in response to ionizing radiation exposure.
The Journal of biological chemistry 1995;270(51):30303-9.
1995: Kharbanda S; Pandey P; Ren R; Mayer B; Zon L; Kufe D
c-Abl activation regulates induction of the SEK1/stress-activated protein kinase pathway in the cellular response to 1-beta-D-arabinofuranosylcytosine.
The Journal of biological chemistry 1995;270(51):30278-81.
1995: Chauhan D; Kharbanda S M; Ogata A; Urashima M; Frank D; Malik N; Kufe D W; Anderson K C
Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells.
The Journal of experimental medicine 1995;182(6):1801-6.
1995: Manome Y; Wen P Y; Hershowitz A; Tanaka T; Rollins B J; Kufe D W; Fine H A
Monocyte chemoattractant protein-1 (MCP-1) gene transduction: an effective tumor vaccine strategy for non-intracranial tumors.
Cancer immunology, immunotherapy : CII 1995;41(4):227-35.
1995: Hallahan D E; Vokes E E; Rubin S J; O'Brien S; Samuels B; Vijaykumar S; Kufe D W; Phillips R; Weichselbaum R R
Phase I dose-escalation study of tumor necrosis factor-alpha and concomitant radiation therapy.
The cancer journal from Scientific American 1995;1(3):204-9.
1995: Pandey P; Kharbanda S; Kufe D
Association of the DF3/MUC1 breast cancer antigen with Grb2 and the Sos/Ras exchange protein.
Cancer research 1995;55(18):4000-3.
1995: Kharbanda S; Ren R; Pandey P; Shafman T D; Feller S M; Weichselbaum R R; Kufe D W
Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents.
Nature 1995;376(6543):785-8.
1995: Shafman T D; Saleem A; Kyriakis J; Weichselbaum R; Kharbanda S; Kufe D W
Defective induction of stress-activated protein kinase activity in ataxia-telangiectasia cells exposed to ionizing radiation.
Cancer research 1995;55(15):3242-5.
1995: Hallahan D E; Mauceri H J; Seung L P; Dunphy E J; Wayne J D; Hanna N N; Toledano A; Hellman S; Kufe D W; Weichselbaum R R
Spatial and temporal control of gene therapy using ionizing radiation.
Nature medicine 1995;1(8):786-91.
1995: Kharbanda S; Saleem A; Yuan Z; Emoto Y; Prasad K V; Kufe D
Stimulation of human monocytes with macrophage colony-stimulating factor induces a Grb2-mediated association of the focal adhesion kinase pp125FAK and dynamin.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(13):6132-6.
1995: Ichige K; Perey L; Vogel C A; Buchegger F; Kufe D
Expression of the DF3-P epitope in human ovarian carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(5):565-71.
1995: Saleem A; Kharbanda S; Yuan Z M; Kufe D
Monocyte colony-stimulating factor stimulates binding of phosphatidylinositol 3-kinase to Grb2.Sos complexes in human monocytes.
The Journal of biological chemistry 1995;270(18):10380-3.
1995: Datta R; Manome Y; Taneja N; Boise L H; Weichselbaum R; Thompson C B; Slapak C A; Kufe D
Overexpression of Bcl-XL by cytotoxic drug exposure confers resistance to ionizing radiation-induced internucleosomal DNA fragmentation.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1995;6(4):363-70.
1995: Yuan Z M; Kharbanda S; Kufe D
1-beta-D-arabinofuranosylcytosine activates tyrosine phosphorylation of p34cdc2 and its association with the Src-like p56/p53lyn kinase in human myeloid leukemia cells.
Biochemistry 1995;34(14):4908.
1995: Saleem A; Yuan Z M; Taneja N; Rubin E; Kufe D W; Kharbanda S M
Activation of serine/threonine protein kinases and early growth response 1 gene expression by tumor necrosis factor in human myeloid leukemia cells.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(8):4150-6.
1995: Chen M; Quintans J; Fuks Z; Thompson C; Kufe D W; Weichselbaum R R
Suppression of Bcl-2 messenger RNA production may mediate apoptosis after ionizing radiation, tumor necrosis factor alpha, and ceramide.
Cancer research 1995;55(5):991-4.
1995: Yuan Z M; Kharbanda S; Kufe D
1-beta-D-arabinofuranosylcytosine activates tyrosine phosphorylation of p34cdc2 and its association with the Src-like p56/p53lyn kinase in human myeloid leukemia cells.
Biochemistry 1995;34(3):1058-63.
1995: Teicher B A; Menon K; Northey D; Liu J; Kufe D W; Kaddurah-Daouk R
Cyclocreatine in cancer chemotherapy.
Cancer chemotherapy and pharmacology 1995;35(5):411-6.
1995: Weichselbaum R R; Beckett M A; Vokes E E; Brachman D G; Haraf D; Hallahan D; Kufe D
Cellular and molecular mechanisms of radioresistance.
Cancer treatment and research 1995;74():131-40.
1994: Slapak C A; Mizunuma N; Kufe D W
Expression of the multidrug resistance associated protein and P-glycoprotein in doxorubicin-selected human myeloid leukemia cells.
Blood 1994;84(9):3113-21.
1994: Kharbanda S; Yuan Z M; Taneja N; Weichselbaum R; Kufe D
p56/p53lyn tyrosine kinase activation in mammalian cells treated with mitomycin C.
Oncogene 1994;9(10):3005-11.
1994: Stone R M; Bernstein S H; Demetri G; Facklam D P; Arthur K; Andersen J; Aster J C; Kufe D
Therapy with recombinant human erythropoietin in patients with myelodysplastic syndromes.
Leukemia research 1994;18(10):769-76.
1994: Manome Y; Abe M; Hagen M F; Fine H A; Kufe D W
Enhancer sequences of the DF3 gene regulate expression of the herpes simplex virus thymidine kinase gene and confer sensitivity of human breast cancer cells to ganciclovir.
Cancer research 1994;54(20):5408-13.
1994: Chauhan D; Kharbanda S; Uchiyama H; Urashima M; Fragoso R; Sen J; Kufe D W; Anderson K C
Identification of upstream signals regulating interleukin-6 gene expression during in vitro treatment of human B cells with pokeweed mitogen.
Blood 1994;84(7):2243-52.
1994: Pantazis P; Mendoza J T; DeJesus A; Rubin E; Kufe D; Giovanella B C
Partial characterization of human leukemia U-937 cell sublines resistant to 9-nitrocamptothecin.
European journal of haematology 1994;53(3):135-44.
1994: Weichselbaum R R; Hallahan D; Fuks Z; Kufe D
Radiation induction of immediate early genes: effectors of the radiation-stress response.
International journal of radiation oncology, biology, physics 1994;30(1):229-34.
1994: Kharbanda S; Yuan Z M; Rubin E; Weichselbaum R; Kufe D
Activation of Src-like p56/p53lyn tyrosine kinase by ionizing radiation.
The Journal of biological chemistry 1994;269(32):20739-43.
1994: Weichselbaum R R; Hallahan D E; Beckett M A; Mauceri H J; Lee H; Sukhatme V P; Kufe D W
Gene therapy targeted by radiation preferentially radiosensitizes tumor cells.
Cancer research 1994;54(16):4266-9.
1994: Toppmeyer D L; Slapak C A; Croop J; Kufe D W
Role of P-glycoprotein in dolastatin 10 resistance.
Biochemical pharmacology 1994;48(3):609-12.
1994: Kharbanda S; Emoto Y; Kisaki H; Saleem A; Kufe D
1-beta-D-arabinofuranosylcytosine activates serine/threonine protein kinases and c-jun gene expression in phorbol ester-resistant myeloid leukemia cells.
Molecular pharmacology 1994;46(1):67-72.
1994: Hallahan D E; Virudachalam S; Kufe D W; Weichselbaum R R
Ketoconazole attenuates radiation-induction of tumor necrosis factor.
International journal of radiation oncology, biology, physics 1994;29(4):777-80.
1994: Kharbanda S; Saleem A; Shafman T; Emoto Y; Weichselbaum R; Kufe D
Activation of the pp90rsk and mitogen-activated serine/threonine protein kinases by ionizing radiation.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(12):5416-20.
1994: Hallahan D E; Bleakman D; Virudachalam S; Lee D; Grdina D; Kufe D W; Weichselbaum R R
The role of intracellular calcium in the cellular response to ionizing radiation.
Radiation research 1994;138(3):392-400.
1994: Hallahan D E; Virudachalam S; Kuchibhotla J; Kufe D W; Weichselbaum R R
Membrane-derived second messenger regulates x-ray-mediated tumor necrosis factor alpha gene induction.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(11):4897-901.
1994: Chauhan D; Kharbanda S M; Uchiyama H; Sukhatme V P; Kufe D W; Anderson K C
Involvement of serum response element in okadaic acid-induced EGR-1 transcription in human T-cells.
Cancer research 1994;54(8):2234-9.
1994: Kharbanda S; Saleem A; Datta R; Yuan Z M; Weichselbaum R; Kufe D
Ionizing radiation induces rapid tyrosine phosphorylation of p34cdc2.
Cancer research 1994;54(6):1412-4.
1994: Kharbanda S; Saleem A; Hirano M; Emoto Y; Sukhatme V; Blenis J; Kufe D
Activation of early growth response 1 gene transcription and pp90rsk during induction of monocytic differentiation.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(3):259-65.
1994: Rubin E; Pantazis P; Bharti A; Toppmeyer D; Giovanella B; Kufe D
Identification of a mutant human topoisomerase I with intact catalytic activity and resistance to 9-nitro-camptothecin.
The Journal of biological chemistry 1994;269(4):2433-9.
1994: Kharbanda S; Saleem A; Emoto Y; Stone R; Rapp U; Kufe D
Activation of Raf-1 and mitogen-activated protein kinases during monocytic differentiation of human myeloid leukemia cells.
The Journal of biological chemistry 1994;269(2):872-8.
1994: Yang K D; Mizobuchi T; Kharbanda S M; Datta R; Huberman E; Kufe D W; Stone R M
All-trans retinoic acid reverses phorbol ester resistance in a human myeloid leukemia cell line.
Blood 1994;83(2):490-6.
1993: Andrews C W; Jessup J M; Goldman H; Hayes D F; Kufe D W; O'Hara C J; Steele G D
Localization of tumor-associated glycoprotein DF3 in normal, inflammatory, and neoplastic lesions of the colon.
Cancer 1993;72(11):3185-90.
1993: Manome Y; Datta R; Taneja N; Shafman T; Bump E; Hass R; Weichselbaum R; Kufe D
Coinduction of c-jun gene expression and internucleosomal DNA fragmentation by ionizing radiation.
Biochemistry 1993;32(40):10607-13.
1993: Kharbanda S; Saleem A; Rubin E; Sukhatme V; Blenis J; Kufe D
Activation of the early growth response 1 gene and nuclear pp90rsk in human myeloid leukemia cells by 1-(beta-D-arabinofuranosyl)cytosine.
Biochemistry 1993;32(35):9137-42.
1993: Hass R; Hirano M; Kharbanda S; Rubin E; Meinhardt G; Kufe D
Resistance to phorbol ester-induced differentiation of a U-937 myeloid leukemia cell variant with a signaling defect upstream to Raf-1 kinase.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993;4(8):657-63.
1993: Slapak C A; Kharbanda S; Saleem A; Kufe D W
Defective translocation of protein kinase C in multidrug-resistant HL-60 cells confers a reversible loss of phorbol ester-induced monocytic differentiation.
The Journal of biological chemistry 1993;268(17):12267-73.
1993: Elson C E; Kufe D; Johnston W W
Immunohistochemical detection and significance of axillary lymph node micrometastases in breast carcinoma. A study of 97 cases.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1993;15(3):171-8.
1993: Kharbanda S; Huberman E; Kufe D
Activation of the jun-D gene during treatment of human myeloid leukemia cells with 1-beta-D-arabinofuranosylcytosine.
Biochemical pharmacology 1993;45(10):2055-61.
1993: Stone R M; Spriggs D R; Arthur K A; Mayer R J; Griffin J; Kufe D W
Recombinant human gamma interferon administered by continuous intravenous infusion in acute myelogenous leukemia and myelodysplastic syndromes.
American journal of clinical oncology 1993;16(2):159-63.
1993: Hass R; Gunji H; Hirano M; Weichselbaum R; Kufe D
Phorbol ester-induced monocytic differentiation is associated with G2 delay and down-regulation of cdc25 expression.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993;4(3):159-66.
1993: Chauhan D; Kharbanda S M; Rubin E; Barut B A; Mohrbacher A; Kufe D W; Anderson K C
Regulation of c-jun gene expression in human T lymphocytes.
Blood 1993;81(6):1540-8.
1993: Hallahan D E; Gius D; Kuchibhotla J; Sukhatme V; Kufe D W; Weichselbaum R R
Radiation signaling mediated by Jun activation following dissociation from a cell type-specific repressor.
The Journal of biological chemistry 1993;268(7):4903-7.
1993: Datta R; Taneja N; Sukhatme V P; Qureshi S A; Weichselbaum R; Kufe D W
Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(6):2419-22.
1993: Kharbanda S; Nakamura T; Kufe D
Induction of the c-jun proto-oncogene by a protein kinase C-dependent mechanism during exposure of human epidermal keratinocytes to ethanol.
Biochemical pharmacology 1993;45(3):675-81.
1993: Datta R; Weichselbaum R; Kufe D W
Ionizing radiation down-regulates histone H1 gene expression by transcriptional and post-transcriptional mechanisms.
Radiation research 1993;133(2):176-81.
1993: Abe M; Kufe D
Characterization of cis-acting elements regulating transcription of the human DF3 breast carcinoma-associated antigen (MUC1) gene.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(1):282-6.
1993: Kharbanda S; Rubin E; Datta R; Hass R; Sukhatme V; Kufe D
Transcriptional regulation of the early growth response 1 gene in human myeloid leukemia cells by okadaic acid.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993;4(1):17-23.
1993: Hallahan D E; Haimovitz-Friedman A; Kufe D W; Fuks Z; Weichselbaum R R
The role of cytokines in radiation oncology.
Important advances in oncology 1993;():71-80.
1993: Manome Y; Weichselbaum R R; Kufe D W; Fine H A
Effect of Bcl-2 on ionizing radiation and 1-beta-D-arabinofuranosylcytosine-induced internucleosomal DNA fragmentation and cell survival in human myeloid leukemia cells.
Oncology research 1993;5(3):139-44.
1992: Nakamura T; Lin L L; Kharbanda S; Knopf J; Kufe D
Macrophage colony stimulating factor activates phosphatidylcholine hydrolysis by cytoplasmic phospholipase A2.
The EMBO journal 1992;11(13):4917-22.
1992: Andreeff M; Stone R; Michaeli J; Young C W; Tong W P; Sogoloff H; Ervin T; Kufe D; Rifkind R A; Marks P A
Hexamethylene bisacetamide in myelodysplastic syndrome and acute myelogenous leukemia: a phase II clinical trial with a differentiation-inducing agent.
Blood 1992;80(10):2604-9.
1992: Perey L; Hayes D F; Kufe D
Effects of differentiating agents on cell surface expression of the breast carcinoma-associated DF3-P epitope.
Cancer research 1992;52(22):6365-70.
1992: Datta R; Rubin E; Sukhatme V; Qureshi S; Hallahan D; Weichselbaum R R; Kufe D W
Ionizing radiation activates transcription of the EGR1 gene via CArG elements.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(21):10149-53.
1992: Hass R; Brach M; Gunji H; Kharbanda S; Kufe D
Inhibition of EGR-1 and NF-kappa B gene expression by dexamethasone during phorbol ester-induced human monocytic differentiation.
Biochemical pharmacology 1992;44(8):1569-76.
1992: Datta R; Hallahan D E; Kharbanda S M; Rubin E; Sherman M L; Huberman E; Weichselbaum R R; Kufe D W
Involvement of reactive oxygen intermediates in the induction of c-jun gene transcription by ionizing radiation.
Biochemistry 1992;31(35):8300-6.
1992: Datta R; Hass R; Gunji H; Weichselbaum R; Kufe D
Down-regulation of cell cycle control genes by ionizing radiation.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1992;3(9):637-44.
1992: Weichselbaum R R; Beckett M A; Hallahan D E; Kufe D W; Vokes E E
Molecular targets to overcome radioresistance.
Seminars in oncology 1992;19(4 Suppl 11):14-20.
1992: Bernstein S H; Kufe D W
Future of basic/clinical hematopoiesis research in the era of hematopoietic growth factor availability.
Seminars in oncology 1992;19(4):441-8.
1992: Kharbanda S; Datta R; Rubin E; Nakamura T; Hass R; Kufe D
Regulation of c-jun expression during induction of monocytic differentiation by okadaic acid.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1992;3(7):391-9.
1992: Schmalbach T K; Datta R; Kufe D W; Sherman M L
Transcriptional regulation of cytokine expression by diethyldithiocarbamate in human HL-60 promyelocytic leukemia cells.
Biochemical pharmacology 1992;44(2):365-71.
1992: Samet J H; Libman H; Steger K A; Dhawan R K; Chen J; Shevitz A H; Dewees-Dunk R; Levenson S; Kufe D; Craven D E
Compliance with zidovudine therapy in patients infected with human immunodeficiency virus, type 1: a cross-sectional study in a municipal hospital clinic.
The American journal of medicine 1992;92(5):495-502.
1992: Perey L; Hayes D F; Maimonis P; Abe M; O'Hara C; Kufe D W
Tumor selective reactivity of a monoclonal antibody prepared against a recombinant peptide derived from the DF3 human breast carcinoma-associated antigen.
Cancer research 1992;52(9):2563-8.
1992: Brach M A; Herrmann F; Yamada H; Bäuerle P A; Kufe D W
Identification of NF-jun, a novel inducible transcription factor that regulates c-jun gene transcription.
The EMBO journal 1992;11(4):1479-86.
1992: Gunji H; Hass R; Kufe D
Internucleosomal DNA fragmentation during phorbol ester-induced monocytic differentiation and G0/G1 arrest.
The Journal of clinical investigation 1992;89(3):954-60.
1992: Hass R; Gunji H; Datta R; Kharbanda S; Hartmann A; Weichselbaum R; Kufe D
Differentiation and retrodifferentiation of human myeloid leukemia cells is associated with reversible induction of cell cycle-regulatory genes.
Cancer research 1992;52(6):1445-50.
1992: Clinton S K; Underwood R; Hayes L; Sherman M L; Kufe D W; Libby P
Macrophage colony-stimulating factor gene expression in vascular cells and in experimental and human atherosclerosis.
The American journal of pathology 1992;140(2):301-16.
1992: Rubin E; Kharbanda S; Gunji H; Weichselbaum R; Kufe D
cis-Diamminedichloroplatinum(II) induces c-jun expression in human myeloid leukemia cells: potential involvement of a protein kinase C-dependent signaling pathway.
Cancer research 1992;52(4):878-82.
1992: Datta R; Imamura K; Goldman S J; Dianoux A C; Kufe D W; Sherman M L
Functional expression of the macrophage colony-stimulating factor receptor in human THP-1 monocytic leukemia cells.
Blood 1992;79(4):904-12.
1992: Brach M A; Herrmann F; Kufe D W
Activation of the AP-1 transcription factor by arabinofuranosylcytosine in myeloid leukemia cells.
Blood 1992;79(3):728-34.
1992: Datta R; Kharbanda S; Kufe D W
Transcriptional and posttranscriptional regulation of H1 histone gene expression by 1-beta-D-arabinofuranosylcytosine.
Molecular pharmacology 1992;41(1):64-8.
1992: Brach M A; Kharbanda S M; Herrmann F; Kufe D W
Activation of the transcription factor kappa B in human KG-1 myeloid leukemia cells treated with 1-beta-D-arabinofuranosylcytosine.
Molecular pharmacology 1992;41(1):60-3.
1992: Damstrup L; Andersen J; Kufe D W; Hayes D F; Poulsen H S
Immunocytochemical determination of the estrogen-regulated proteins Mr 24,000, Mr 52,000 and DF3 breast cancer associated antigen: clinical value in advanced breast cancer and correlation with estrogen receptor.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1992;3(1):71-7.
1992: Spriggs D R; Deutsch S; Kufe D W
Genomic structure, induction, and production of TNF-alpha.
Immunology series 1992;56():3-34.
1992: Weichselbaum R R; Hallahan D E; Sukhatme V P; Kufe D W
Gene therapy targeted by ionizing radiation.
International journal of radiation oncology, biology, physics 1992;24(3):565-7.
1991: Ohno T; Terada M; Yoneda Y; Shea K W; Chambers R F; Stroka D M; Nakamura M; Kufe D W
A broadly neutralizing monoclonal antibody that recognizes the V3 region of human immunodeficiency virus type 1 glycoprotein gp120.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(23):10726-9.
1991: Bernstein S H; Kharbanda S M; Sherman M L; Stone R M; Kufe D W
Inhibition of protein kinase C is associated with a decrease in c-myc expression in human myeloid leukemia cells.
FEBS letters 1991;294(1-2):73-6.
1991: Kharbanda S; Rubin E; Gunji H; Hinz H; Giovanella B; Pantazis P; Kufe D
Camptothecin and its derivatives induce expression of the c-jun protooncogene in human myeloid leukemia cells.
Cancer research 1991;51(24):6636-42.
1991: Hass R; Pfannkuche H J; Kharbanda S; Gunji H; Meyer G; Hartmann A; Hidaka H; Resch K; Kufe D; Goppelt-Strübe M
Protein kinase C activation and protooncogene expression in differentiation/retrodifferentiation of human U-937 leukemia cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1991;2(11):541-8.
1991: Hallahan D E; Virudachalam S; Beckett M; Sherman M L; Kufe D; Weichselbaum R R
Mechanisms of X-ray-mediated protooncogene c-jun expression in radiation-induced human sarcoma cell lines.
International journal of radiation oncology, biology, physics 1991;21(6):1677-81.
1991: Hass R; Brach M; Kharbanda S; Giese G; Traub P; Kufe D
Inhibition of phorbol ester-induced monocytic differentiation by dexamethasone is associated with down-regulation of c-fos and c-jun (AP-1).
Journal of cellular physiology 1991;149(1):125-31.
1991: Yamada H; Iwase S; Mohri M; Kufe D
Involvement of a nuclear factor-kappa B-like protein in induction of the macrophage colony-stimulating factor gene by tumor necrosis factor.
Blood 1991;78(8):1988-95.
1991: Hallahan D E; Virudachalam S; Sherman M L; Huberman E; Kufe D W; Weichselbaum R R
Tumor necrosis factor gene expression is mediated by protein kinase C following activation by ionizing radiation.
Cancer research 1991;51(17):4565-9.
1991: Kharbanda S; Datta R; Kufe D
Regulation of c-jun gene expression in HL-60 leukemia cells by 1-beta-D-arabinofuranosylcytosine. Potential involvement of a protein kinase C dependent mechanism.
Biochemistry 1991;30(32):7947-52.
1991: Takeyama H; Wakamiya N; O'Hara C; Arthur K; Niloff J; Kufe D; Sakarai K; Spriggs D
Tumor necrosis factor expression by human ovarian carcinoma in vivo.
Cancer research 1991;51(16):4476-80.
1991: Brach M A; Hass R; Sherman M L; Gunji H; Weichselbaum R; Kufe D
Ionizing radiation induces expression and binding activity of the nuclear factor kappa B.
The Journal of clinical investigation 1991;88(2):691-5.
1991: Kharbanda S; Nakamura T; Stone R; Hass R; Bernstein S; Datta R; Sukhatme V P; Kufe D
Expression of the early growth response 1 and 2 zinc finger genes during induction of monocytic differentiation.
The Journal of clinical investigation 1991;88(2):571-7.
1991: Maimonis P; Hayes D F; Schaffel S; Kufe D
Lung cancer-associated protein: development and characterization of a new assay that detects a circulating lung cancer marker.
Cancer research 1991;51(15):3838-42.
1991: Bernstein S H; Sherman M L; Hass R; Nakamura T; Kharbanda S; Kufe D W
Effects of hexamethylene bisacetamide on induction of monocytic differentiation of human U-937 myeloid leukemia cells.
Biochemical pharmacology 1991;42(2):403-7.
1991: Datta R; Nakamura T; Sherman M L; Kufe D
Regulation of jun-B expression by a cyclic AMP (cAMP)-dependent mechanism in human myeloid cells.
Blood 1991;78(1):83-8.
1991: Bernstein S H; Kharbanda S M; Sherman M L; Sukhatme V P; Kufe D W
Posttranscriptional regulation of the zinc finger-encoding EGR-1 gene by granulocyte-macrophage colony-stimulating factor in human U-937 monocytic leukemia cells: involvement of a pertussis toxin-sensitive G protein.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1991;2(6):273-8.
1991: Rubin E; Kharbanda S; Gunji H; Kufe D
Activation of the c-jun protooncogene in human myeloid leukemia cells treated with etoposide.
Molecular pharmacology 1991;39(6):697-701.
1991: Nakamura T; Datta R; Kharbanda S; Kufe D
Regulation of jun and fos gene expression in human monocytes by the macrophage colony-stimulating factor.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1991;2(6):267-72.
1991: Sherman M L; Datta R; Hallahan D E; Weichselbaum R R; Kufe D W
Regulation of tumor necrosis factor gene expression by ionizing radiation in human myeloid leukemia cells and peripheral blood monocytes.
The Journal of clinical investigation 1991;87(5):1794-7.
1991: Chambers R F; Terada M; Kufe D; Ohno T
Shaking HIV-1 infected cells indicates novel behavior of MN strain.
AIDS research and human retroviruses 1991;7(5):459-63.
1991: Weichselbaum R R; Hallahan D E; Sukhatme V; Dritschilo A; Sherman M L; Kufe D W
Biological consequences of gene regulation after ionizing radiation exposure.
Journal of the National Cancer Institute 1991;83(7):480-4.
1991: Hallahan D E; Sukhatme V P; Sherman M L; Virudachalam S; Kufe D; Weichselbaum R R
Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(6):2156-60.
1991: Pantazis P; Kharbanda S; Goustin A S; Galanopoulos T; Kufe D
Coexpression of the genes for platelet-derived growth factor B-chain receptor and macrophage colony-stimulating factor 1 receptor during monocytic differentiation.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(6):2481-5.
1991: Datta R; Sherman M L; Stone R M; Kufe D
Expression of the jun-B gene during induction of monocytic differentiation.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1991;2(1):43-9.
1991: Gunji H; Kharbanda S; Kufe D
Induction of internucleosomal DNA fragmentation in human myeloid leukemia cells by 1-beta-D-arabinofuranosylcytosine.
Cancer research 1991;51(2):741-3.
1991: Brach M; Stone R; Kufe D
CSFs in combination with cytosine arabinoside, an inhibitor of DNA synthesis: potential strategies for the treatment of myeloid disorders.
Biotechnology therapeutics 1991;2(3-4):269-83.
1990: Dhawan R K; Kharbanda S; Nakamura M; Ohno T; Kufe D
Effects of granulocyte-macrophage colony-stimulating factor on 3'-azido-3'-deoxythymidine uptake, phosphorylation and nucleotide retention in human U-937 cells.
Biochemical pharmacology 1990;40(12):2695-700.
1990: Stone R M; Spriggs D R; Dhawan R K; Arthur K A; Mayer R J; Kufe D W
A phase I study of intermittent continuous infusion high dose cytosine arabinoside for acute leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1990;4(12):843-7.
1990: Nakamura T; Datta R; Sherman M L; Kufe D
Regulation of c-jun gene expression by cAMP in HL-60 myeloid leukemia cells.
The Journal of biological chemistry 1990;265(35):22011-5.
1990: Kharbanda S M; Sherman M L; Kufe D W
Transcriptional regulation of c-jun gene expression by arabinofuranosylcytosine in human myeloid leukemia cells.
The Journal of clinical investigation 1990;86(5):1517-23.
1990: Spriggs D R; Sherman M L; Imamura K; Mohri M; Rodriguez C; Robbins G; Kufe D W
Phospholipase A2 activation and autoinduction of tumor necrosis factor gene expression by tumor necrosis factor.
Cancer research 1990;50(22):7101-7.
1990: Datta R; Kharbanda S; Kufe D
Regulation of jun-B gene expression by 1-beta-D-arabinofuranosyl-cytosine in human myeloid leukemia cells.
Molecular pharmacology 1990;38(4):435-9.
1990: Maimonis P; Hayes D F; O'Hara C; Kufe D
Detection and characterization of a high molecular weight human lung carcinoma-associated glycoprotein.
Cancer research 1990;50(20):6738-43.
1990: Stone R M; Imamura K; Datta R; Sherman M L; Kufe D W
Inhibition of phorbol ester-induced monocytic differentiation and c-fms gene expression by dexamethasone: potential involvement of arachidonic acid metabolites.
Blood 1990;76(6):1225-32.
1990: Hayes D F; Silberstein D S; Rodrique S W; Kufe D W
DF3 antigen, a human epithelial cell mucin, inhibits adhesion of eosinophils to antibody-coated targets.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(3):962-70.
1990: Imamura K; Dianoux A; Nakamura T; Kufe D
Colony-stimulating factor 1 activates protein kinase C in human monocytes.
The EMBO journal 1990;9(8):2423-8, 2389.
1990: Sherman M L; Datta R; Hallahan D E; Weichselbaum R R; Kufe D W
Ionizing radiation regulates expression of the c-jun protooncogene.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(15):5663-6.
1990: Hallahan D E; Beckett M A; Kufe D; Weichselbaum R R
The interaction between recombinant human tumor necrosis factor and radiation in 13 human tumor cell lines.
International journal of radiation oncology, biology, physics 1990;19(1):69-74.
1990: Datta R; Sherman M L; Kufe D W
Regulation of proto-oncogene and tumor necrosis factor gene expression by ethanol in HL-60 myeloid leukemia cells.
Blood 1990;76(2):298-301.
1990: Abe M; Kufe D
Transcriptional regulation of DF3 gene expression in human MCF-7 breast carcinoma cells.
Journal of cellular physiology 1990;143(2):226-31.
1990: Mohri M; Spriggs D R; Kufe D
Effects of lipopolysaccharide on phospholipase A2 activity and tumor necrosis factor expression in HL-60 cells.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(7):2678-82.
1990: Nakamura T; Kharbanda S; Spriggs D; Kufe D
Effects of dexamethasone on induction of monocytic differentiation in human U-937 cells by dimethylsulfoxide.
Journal of cellular physiology 1990;142(2):261-7.
1990: Tondini C; Pap S A; Hayes D F; Elias A D; Kufe D W
Evaluation of monoclonal antibody DF3 conjugated with ricin as a specific immunotoxin for in vitro purging of human bone marrow.
Cancer research 1990;50(4):1170-5.
1990: Sherman M L; Stone R M; Datta R; Bernstein S H; Kufe D W
Transcriptional and post-transcriptional regulation of c-jun expression during monocytic differentiation of human myeloid leukemic cells.
The Journal of biological chemistry 1990;265(6):3320-3.
1990: Sherman M L; Weber B L; Datta R; Kufe D W
Transcriptional and posttranscriptional regulation of macrophage-specific colony stimulating factor gene expression by tumor necrosis factor. Involvement of arachidonic acid metabolites.
The Journal of clinical investigation 1990;85(2):442-7.
1990: Kharbanda S M; Sherman M L; Kufe D W
Effects of tiazofurin on guanine nucleotide binding regulatory proteins in HL-60 cells.
Blood 1990;75(3):583-8.
1990: Kharbanda S; Datta R; Kufe D
Induction of c-fos gene expression by arabinofuranosylcytosine in human KG-1 leukemia cells.
Cancer communications 1990;2(12):409-14.
1990: Kharbanda S; Nakamura T; Datta R; Sherman M L; Kufe D
Induction of monocytic differentiation by tumor necrosis factor in phorbol ester-resistant KG-1a cells.
Cancer communications 1990;2(10):327-32.
1989: Tondini C; Hayes D F; Kufe D W
Circulating tumor markers in breast cancer.
Hematology/oncology clinics of North America 1989;3(4):653-74.
1989: Hallahan D E; Spriggs D R; Beckett M A; Kufe D W; Weichselbaum R R
Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(24):10104-7.
1989: Abe M; Siddiqui J; Kufe D
Sequence analysis of the 5' region of the human DF3 breast carcinoma-associated antigen gene.
Biochemical and biophysical research communications 1989;165(2):644-9.
1989: Merlo G R; Siddiqui J; Cropp C S; Liscia D S; Lidereau R; Callahan R; Kufe D W
Frequent alteration of the DF3 tumor-associated antigen gene in primary human breast carcinomas.
Cancer research 1989;49(24 Pt 1):6966-71.
1989: Demetri G D; Spriggs D R; Sherman M L; Arthur K A; Imamura K; Kufe D W
A phase I trial of recombinant human tumor necrosis factor and interferon-gamma: effects of combination cytokine administration in vivo.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1989;7(10):1545-53.
1989: Sariban E; Imamura K; Sherman M; Rothwell V; Pantazis P; Kufe D
Downregulation of c-fms gene expression in human monocytes treated with phorbol esters and colony-stimulating factor 1.
Blood 1989;74(1):123-9.
1989: Brouckaert P; Spriggs D R; Demetri G; Kufe D W; Fiers W
Circulating interleukin 6 during a continuous infusion of tumor necrosis factor and interferon gamma.
The Journal of experimental medicine 1989;169(6):2257-62.
1989: Abe M; Kufe D
Structural analysis of the DF3 human breast carcinoma-associated protein.
Cancer research 1989;49(11):2834-9.
1989: Imamura K; Spriggs D; Ohno T; Kufe D
Effects of botulinum toxin type D on secretion of tumor necrosis factor from human monocytes.
Molecular and cellular biology 1989;9(5):2239-43.
1989: Ohno Y; Spriggs D; Matsukage A; Ohno T; Kufe D
Sequence-specific inhibition of DNA strand elongation by incorporation of 9-beta-D-arabinofuranosyladenine.
Cancer research 1989;49(8):2077-81.
1989: Sherman M L; Shafman T D; Colman M S; Kufe D W
Tiazofurin induction of mouse erythroleukemia cell hemoglobin production in the absence of commitment or changes in protooncogene expression.
Blood 1989;73(2):431-4.
1989: Weber B; Horiguchi J; Luebbers R; Sherman M; Kufe D
Posttranscriptional stabilization of c-fms mRNA by a labile protein during human monocytic differentiation.
Molecular and cellular biology 1989;9(2):769-75.
1989: Wakamiya N; Stone R; Takeyama H; Spriggs D; Kufe D
Detection of tumor necrosis factor gene expression at a cellular level in human acute myeloid leukemias.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1989;3(1):51-6.
1989: Horiguchi J; Spriggs D; Imamura K; Stone R; Luebbers R; Kufe D
Role of arachidonic acid metabolism in transcriptional induction of tumor necrosis factor gene expression by phorbol ester.
Molecular and cellular biology 1989;9(1):252-8.
1989: Hull S R; Bright A; Carraway K L; Abe M; Hayes D F; Kufe D W
Oligosaccharide differences in the DF3 sialomucin antigen from normal human milk and the BT-20 human breast carcinoma cell line.
Cancer communications 1989;1(4):261-7.
1989: Kharbanda S M; Miyazaki K; Takeyama H; Sherman M L; Spriggs D R; Carney W P; Kufe D W
Effects of tiazofurin on globin and proto-oncogene expression in K562 erythroleukemia cells.
Cancer communications 1989;1(3):191-7.
1988: Horiguchi J; Sherman M L; Sampson-Johannes A; Weber B L; Kufe D W
CSF-1 and C-FMS gene expression in human carcinoma cell lines.
Biochemical and biophysical research communications 1988;157(1):395-401.
1988: Kharbanda S M; Sherman M L; Spriggs D R; Kufe D W
Effects of tiazofurin on protooncogene expression during HL-60 cell differentiation.
Cancer research 1988;48(21):5965-8.
1988: Sariban E; Sitaras N M; Antoniades H N; Kufe D W; Pantazis P
Expression of platelet-derived growth factor (PDGF)-related transcripts and synthesis of biologically active PDGF-like proteins by human malignant epithelial cell lines.
The Journal of clinical investigation 1988;82(4):1157-64.
1988: Imamura K; Kufe D
Colony-stimulating factor 1-induced Na+ influx into human monocytes involves activation of a pertussis toxin-sensitive GTP-binding protein.
The Journal of biological chemistry 1988;263(28):14093-8.
1988: Spriggs D R; Sherman M L; Michie H; Arthur K A; Imamura K; Wilmore D; Frei E; Kufe D W
Recombinant human tumor necrosis factor administered as a 24-hour intravenous infusion. A phase I and pharmacologic study.
Journal of the National Cancer Institute 1988;80(13):1039-44.
1988: Horiguchi J; Sariban E; Kufe D
Transcriptional and posttranscriptional regulation of CSF-1 gene expression in human monocytes.
Molecular and cellular biology 1988;8(9):3951-4.
1988: Stone R M; Weber B L; Spriggs D R; Kufe D W
Phospholipase C activates protein kinase C and induces monocytic differentiation of HL-60 cells.
Blood 1988;72(2):739-44.
1988: Sariban E; Kufe D
Expression of the platelet-derived growth factor 1 and 2 genes in human myeloid cell lines and monocytes.
Cancer research 1988;48(16):4498-502.
1988: Tondini C; Hayes D F; Gelman R; Henderson I C; Kufe D W
Comparison of CA15-3 and carcinoembryonic antigen in monitoring the clinical course of patients with metastatic breast cancer.
Cancer research 1988;48(14):4107-12.
1988: Imamura K; Sherman M L; Spriggs D; Kufe D
Effect of tumor necrosis factor on GTP binding and GTPase activity in HL-60 and L929 cells.
The Journal of biological chemistry 1988;263(21):10247-53.
1988: Stone R M; Sariban E; Pettit G R; Kufe D W
Bryostatin 1 activates protein kinase C and induces monocytic differentiation of HL-60 cells.
Blood 1988;72(1):208-13.
1988: Sariban E; Imamura K; Luebbers R; Kufe D
Transcriptional and posttranscriptional regulation of tumor necrosis factor gene expression in human monocytes.
The Journal of clinical investigation 1988;81(5):1506-10.
1988: Spriggs D R; Robbins G; Arthur K; Mayer R J; Kufe D
Prolonged high dose ARA-C infusions in acute leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1988;2(5):304-6.
1988: Thor A; Viglione M J; Ohuchi N; Simpson J; Steis R; Cousar J; Lippman M; Kufe D W; Schlom J
Comparison of monoclonal antibodies for the detection of occult breast carcinoma metastases in bone marrow.
Breast cancer research and treatment 1988;11(2):133-45.
1988: Siddiqui J; Abe M; Hayes D; Shani E; Yunis E; Kufe D
Isolation and sequencing of a cDNA coding for the human DF3 breast carcinoma-associated antigen.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(7):2320-3.
1988: Rambaldi A; Wakamiya N; Vellenga E; Horiguchi J; Warren M K; Kufe D; Griffin J D
Expression of the macrophage colony-stimulating factor and c-fms genes in human acute myeloblastic leukemia cells.
The Journal of clinical investigation 1988;81(4):1030-5.
1988: Ohno Y; Spriggs D; Matsukage A; Ohno T; Kufe D
Effects of 1-beta-D-arabinofuranosylcytosine incorporation on elongation of specific DNA sequences by DNA polymerase beta.
Cancer research 1988;48(6):1494-8.
1988: Sherman M L; Shafman T D; Kufe D W
Modulation of cyclic AMP levels and differentiation by adenosine analogs in mouse erythroleukemia cells.
Journal of cellular physiology 1988;134(3):429-36.
1988: Sherman M L; Spriggs D R; Arthur K A; Imamura K; Frei E; Kufe D W
Recombinant human tumor necrosis factor administered as a five-day continuous infusion in cancer patients: phase I toxicity and effects on lipid metabolism.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1988;6(2):344-50.
1988: Hayes D F; Sekine H; Marcus D; Alper C A; Kufe D W
Genetically determined polymorphism of the circulating human breast cancer-associated DF3 antigen.
Blood 1988;71(2):436-40.
1988: Sariban E; Mitchell T; Rambaldi A; Kufe D W
c-sis but not c-fos gene expression is lineage specific in human myeloid cells.
Blood 1988;71(2):488-93.
1988: Spriggs D R; Imamura K; Rodriguez C; Sariban E; Kufe D W
Tumor necrosis factor expression in human epithelial tumor cell lines.
The Journal of clinical investigation 1988;81(2):455-60.
1988: Sariban E; Luebbers R; Kufe D
Transcriptional and posttranscriptional control of c-fos gene expression in human monocytes.
Molecular and cellular biology 1988;8(1):340-6.
1988: Hayes D F; Noska M A; Kufe D W; Zalutsky M R
Effect of radioiodination on the binding of monoclonal antibody DF3 to breast carcinoma cells.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1988;15(3):235-41.
1987: Spriggs D; Robbins G; Ohno Y; Kufe D
Detection of 1-beta-D-arabinofuranosylcytosine incorporation into DNA in vivo.
Cancer research 1987;47(24 Pt 1):6532-6.
1987: Imamura K; Spriggs D; Kufe D
Expression of tumor necrosis factor receptors on human monocytes and internalization of receptor bound ligand.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(9):2989-92.
1987: Spriggs D; Imamura K; Rodriguez C; Horiguchi J; Kufe D W
Induction of tumor necrosis factor expression and resistance in a human breast tumor cell line.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(18):6563-6.
1987: Ohuchi N; Page D L; Merino M J; Viglione M J; Kufe D W; Schlom J
Expression of tumor-associated antigen (DF3) in atypical hyperplasias and in situ carcinomas of the human breast.
Journal of the National Cancer Institute 1987;79(1):109-17.
1987: Abe M; Kufe D W
Identification of a family of high molecular weight tumor-associated glycoproteins.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(1):257-61.
1987: Kufe D W; Spriggs D R; Griffin J D
Pharmacologic studies of low-dose and high-dose continuous infusion cytosine arabinoside.
Seminars in oncology 1987;14(2 Suppl 1):149-58.
1987: Cannistra S A; Rambaldi A; Spriggs D R; Herrmann F; Kufe D; Griffin J D
Human granulocyte-macrophage colony-stimulating factor induces expression of the tumor necrosis factor gene by the U937 cell line and by normal human monocytes.
The Journal of clinical investigation 1987;79(6):1720-8.
1987: Wakamiya N; Horiguchi J; Kufe D
Detection of c-fms and CSF-1 RNA by in situ hybridization.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1987;1(6):518-20.
1987: Lundy J; Mishriki Y; Varma A O; Kufe D; Schuss A
Tumor-associated antigens in bilateral breast cancer.
Journal of surgical oncology 1987;35(1):24-9.
1987: Sariban E; Mitchell T; Kufe D
Expression of the c-raf protooncogene in human hematopoietic cells and cell lines.
Blood 1987;69(5):1437-40.
1987: Horiguchi J; Warren M K; Kufe D
Expression of the macrophage-specific colony-stimulating factor in human monocytes treated with granulocyte-macrophage colony-stimulating factor.
Blood 1987;69(4):1259-61.
1987: Sariban E; Mitchell T; Griffin J; Kufe D W
Effects of interferon-gamma on proto-oncogene expression during induction of human monocytic differentiation.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(6):1954-8.
1987: Band H; Corredor V; Lustgarten J; Huebner K; Griffin J D; Kufe D W; Yunis E J
Southern blot analysis of BII cell line--a putative variant of HL-60.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1987;1(2):142-5.
1987: Spriggs D R; Sherman M L; Frei E; Kufe D W
Clinical studies with tumour necrosis factor.
Ciba Foundation symposium 1987;131():206-27.
1986: Spriggs D R; Robbins G; Kufe D W
Effects of cis-diamminedichloroplatinum on DNA incorporation and cytotoxicity of 1-beta-D-arabinofuranosylcytosine.
Biochemical pharmacology 1986;35(23):4297-302.
1986: Horiguchi J; Warren M K; Ralph P; Kufe D
Expression of the macrophage specific colony-stimulating factor (CSF-1) during human monocytic differentiation.
Biochemical and biophysical research communications 1986;141(3):924-30.
1986: Spriggs D R; Stone R M; Kufe D W
The treatment of myelodysplastic syndromes.
Clinics in haematology 1986;15(4):1081-107.
1986: Spriggs D R; Stopa E; Mayer R J; Schoene W; Kufe D W
Fludarabine phosphate (NSC 312878) infusions for the treatment of acute leukemia: phase I and neuropathological study.
Cancer research 1986;46(11):5953-8.
1986: Mitchell T; Sariban E; Kufe D
Effects of 1-beta-D-arabinofuranosylcytosine on proto-oncogene expression in human U-937 cells.
Molecular pharmacology 1986;30(4):398-402.
1986: Friedman E L; Hayes D F; Kufe D W
Reactivity of monoclonal antibody DF3 with a high molecular weight antigen expressed in human ovarian carcinomas.
Cancer research 1986;46(10):5189-94.
1986: Hayes D F; Zurawski V R; Kufe D W
Comparison of circulating CA15-3 and carcinoembryonic antigen levels in patients with breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1986;4(10):1542-50.
1986: Pantazis P; Sariban E; Kufe D; Antoniades H N
Induction of c-sis gene expression and synthesis of platelet-derived growth factor in human myeloid leukemia cells during monocytic differentiation.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(17):6455-9.
1986: Kaysen J; Spriggs D; Kufe D
Incorporation of 5-fluorodeoxycytidine and metabolites into nucleic acids of human MCF-7 breast carcinoma cells.
Cancer research 1986;46(9):4534-8.
1986: Sherman M L; Shafman T D; Coward J K; Kufe D W
Selective inhibition of spermidine biosynthesis and differentiation by S-adenosyl-1,8-diamino-3-thiooctane in murine erythroleukemia cells.
Biochemical pharmacology 1986;35(15):2633-6.
1986: Hayes D F; Zalutsky M R; Kaplan W; Noska M; Thor A; Colcher D; Kufe D W
Pharmacokinetics of radiolabeled monoclonal antibody B6.2 in patients with metastatic breast cancer.
Cancer research 1986;46(6):3157-63.
1986: Watanabe T; Sherman M; Shafman T; Iwata T; Kufe D
Effects of ornithine decarboxylase inhibition on c-myc expression during murine erythroleukemia cell proliferation and differentiation.
Journal of cellular physiology 1986;127(3):480-4.
1986: Iwata T; Watanabe T; Kufe D W
Effects of 5-fluorouracil on globin mRNA synthesis in murine erythroleukemia cells.
Biochemistry 1986;25(9):2703-7.
1986: Spriggs D; Robbins G; Mitchell T; Kufe D
Incorporation of 9-beta-D-arabinofuranosyl-2-fluoroadenine into HL-60 cellular RNA and DNA.
Biochemical pharmacology 1986;35(2):247-52.
1986: Sherman M L; Shafman T D; Kufe D W
Inhibitory effects of theophylline and dibutyryl cAMP on murine erythroleukemia cell differentiation.
Biochemical and biophysical research communications 1986;134(2):845-51.
1986: Abe M; Kufe D
Effects of maturational agents on expression and secretion of two partially characterized high molecular weight milk-related glycoproteins in MCF-7 breast carcinoma cells.
Journal of cellular physiology 1986;126(1):126-32.
1986: Spriggs D R; Sokal J E; Griffin J; Kufe D W
Low dose ara-C administered by continuous subcutaneous infusion: a pharmacologic evaluation.
Cancer drug delivery 1986;3(3):211-6.
1985: Sekine H; Ohno T; Kufe D W
Purification and characterization of a high molecular weight glycoprotein detectable in human milk and breast carcinomas.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(5):3610-5.
1985: Griffin J D; Larcom P; Kufe D W
TPA induces differentiation of purified human myeloblasts in the absence of proliferation.
Experimental hematology 1985;13(10):1025-32.
1985: Sherman M L; Shafman T D; Spriggs D R; Kufe D W
Inhibition of murine erythroleukemia cell differentiation by 3-deazaadenosine.
Cancer research 1985;45(11 Pt 2):5830-4.
1985: Sekine H; Hayes D F; Ohno T; Keefe K A; Schaetzl E; Bast R C; Knapp R; Kufe D W
Circulating DF3 and CA125 antigen levels in serum from patients with epithelial ovarian carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1985;3(10):1355-63.
1985: Spriggs D R; Robbins G; Takvorian T; Kufe D W
Continuous infusion of high-dose 1-beta-D-arabinofuranosylcytosine: a phase I and pharmacological study.
Cancer research 1985;45(8):3932-6.
1985: Griffin J D; Spriggs D; Wisch J S; Kufe D W
Treatment of preleukemic syndromes with continuous intravenous infusion of low-dose cytosine arabinoside.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1985;3(7):982-91.
1985: Fram R J; Kufe D W
Effect of 1-beta-D-arabinofuranosyl cytosine and hydroxyurea on the repair of X-ray-induced DNA single-strand breaks in human leukemic blasts.
Biochemical pharmacology 1985;34(14):2557-60.
1985: Sariban E; Mitchell T; Kufe D
Expression of the c-fms proto-oncogene during human monocytic differentiation.
Nature 1985;316(6023):64-6.
1985: Kufe D W; Spriggs D R
Biochemical and cellular pharmacology of cytosine arabinoside.
Seminars in oncology 1985;12(2 Suppl 3):34-48.
1985: Kufe D W; Griffin J D; Spriggs D R
Cellular and clinical pharmacology of low-dose ara-C.
Seminars in oncology 1985;12(2 Suppl 3):200-7.
1985: Watanabe T; Mitchell T; Sariban E; Sabbath K; Griffin J; Kufe D
Effects of 1-beta-D-arabinofuranosylcytosine and phorbol ester on differentiation of human K562 erythroleukemia cells.
Molecular pharmacology 1985;27(6):683-8.
1985: Spriggs D; Griffin J; Wisch J; Kufe D
Clinical pharmacology of low-dose cytosine arabinoside.
Blood 1985;65(5):1087-9.
1985: Hayes D F; Sekine H; Ohno T; Abe M; Keefe K; Kufe D W
Use of a murine monoclonal antibody for detection of circulating plasma DF3 antigen levels in breast cancer patients.
The Journal of clinical investigation 1985;75(5):1671-8.
1985: Watanabe T; Shafman T; Kufe D W
Requirement of spermidine for induction of both heme synthesis and globin transcription in murine erythroleukemia cells.
Journal of cellular physiology 1985;122(3):435-40.
1985: Watanabe T; Sariban E; Mitchell T; Kufe D
Human c-myc and N-ras expression during induction of HL-60 cellular differentiation.
Biochemical and biophysical research communications 1985;126(3):999-1005.
1985: Fram R J; Kufe D W
Inhibition of DNA excision repair and the repair of X-ray-induced DNA damage by cytosine arabinoside and hydroxyurea.
Pharmacology & therapeutics 1985;31(3):165-76.
1985: Zalutsky M R; Colcher D; Kaplan W D; Kufe D W
Radioiodinated B6.2 monoclonal antibody: further characterization of a potential radiopharmaceutical for the identification of breast tumors.
International journal of nuclear medicine and biology 1985;12(3):227-33.
1985: Lundy J; Thor A; Maenza R; Schlom J; Forouhar F; Testa M; Kufe D
Monoclonal antibody DF3 correlates with tumor differentiation and hormone receptor status in breast cancer patients.
Breast cancer research and treatment 1985;5(3):269-76.
1985: Schlom J; Colcher D; Hand P H; Greiner J; Wunderlich D; Weeks M; Fisher P B; Noguchi P; Pestka S; Kufe D
Monoclonal antibodies reactive with breast tumor-associated antigens.
Advances in cancer research 1985;43():143-73.
1984: Schlom J; Greiner J; Hand P H; Colcher D; Inghirami G; Weeks M; Pestka S; Fisher P B; Noguchi P; Kufe D
Monoclonal antibodies to breast cancer-associated antigens as potential reagents in the management of breast cancer.
Cancer 1984;54(11 Suppl):2777-94.
1984: Shafman T D; Sherman M L; Kufe D W
Effect of 5'-methylthioadenosine on induction of murine erythroleukemia cell differentiation.
Biochemical and biophysical research communications 1984;124(1):172-7.
1984: Abe M; Kufe D W
Sodium butyrate induction of milk-related antigens in human MCF-7 breast carcinoma cells.
Cancer research 1984;44(10):4574-7.
1984: Kufe D W; Griffin J; Mitchell T; Shafman T
Polyamine requirements for induction of HL-60 promyelocyte differentiation by leukocyte-conditioned medium and phorbol ester.
Cancer research 1984;44(10):4281-4.
1984: Luisi-DeLuca C; Mitchell T; Spriggs D; Kufe D W
Induction of terminal differentiation in human K562 erythroleukemia cells by arabinofuranosylcytosine.
The Journal of clinical investigation 1984;74(3):821-7.
1984: Sugiura M; Fram R; Munroe D; Kufe D
DNA strand scission and ADP-ribosyltransferase activity during murine erythroleukemia cell differentiation.
Developmental biology 1984;104(2):484-8.
1984: Kufe D; Spriggs D; Egan E M; Munroe D
Relationships among Ara-CTP pools, formation of (Ara-C)DNA, and cytotoxicity of human leukemic cells.
Blood 1984;64(1):54-8.
1984: Herrick D; Kufe D W
Lethality associated with incorporation of 5-fluorouracil into preribosomal RNA.
Molecular pharmacology 1984;26(1):135-40.
1984: Kufe D W; Munroe D; Herrick D; Egan E; Spriggs D
Effects of 1-beta-D-arabinofuranosylcytosine incorporation on eukaryotic DNA template function.
Molecular pharmacology 1984;26(1):128-34.
1984: Kufe D W; Herrick D; Gunner L
Uracil enhancement of 5-fluorodexoyuridine incorporation into human breast carcinoma deoxyribonucleic acid.
Biochemical pharmacology 1984;33(14):2329-31.
1984: Szpak C A; Johnston W W; Lottich S C; Kufe D; Thor A; Schlom J
Patterns of reactivity of four novel monoclonal antibodies (B72.3, DF3, B1.1 and B6.2) with cells in human malignant and benign effusions.
Acta cytologica 1984;28(4):356-67.
1984: Sugiura M; Shafman T; Mitchell T; Griffin J; Kufe D
Involvement of spermidine in proliferation and differentiation of human promyelocytic leukemia cells.
Blood 1984;63(5):1153-8.
1984: Sugiura M; Shafman T; Kufe D
Effects of polyamine depletion on proliferation and differentiation of murine erythroleukemia cells.
Cancer research 1984;44(4):1440-4.
1984: Kufe D W; Weichselbaum R; Egan E M; Dahlberg W; Fram R J
Lethal effects of 1-beta-D-arabinofuranosylcytosine incorporation into deoxyribonucleic acid during ultraviolet repair.
Molecular pharmacology 1984;25(2):322-6.
1984: Kufe D; Herrick D; Crumpacker C; Schnipper L
Incorporation of 1-beta-D-arabinofuranosylcytosine into DNA from herpes simplex virus resistant to 9-beta-D-arabinofuranosyladenine.
Cancer research 1984;44(1):69-73.
1984: Munroe D; Sugiura M; Griffin J; Kufe D
Effect of ara-A on differentiation and proliferation of HL-60 cells.
Leukemia research 1984;8(3):355-61.
1984: Abe M; Kufe D W
Effect of sodium butyrate on human breast carcinoma (MCF-7) cellular proliferation, morphology, and CEA production.
Breast cancer research and treatment 1984;4(4):269-74.
1984: Fram R J; Kufe D W
The effect of inhibitors of DNA synthesis on DNA repair.
Nucleic acids symposium series 1984;(13):95-107.
1984: Peters W P; Weiss G; Kufe D W
Phase-I trial of combination therapy with continuous-infusion MMPR and continuous-infusion 5-FU.
Cancer chemotherapy and pharmacology 1984;13(2):136-8.
1984: Kufe D; Inghirami G; Abe M; Hayes D; Justi-Wheeler H; Schlom J
Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors.
Hybridoma 1984;3(3):223-32.
1983: Egan E M; Justi-Wheeler H; Kufe D W
Alkali lability of deoxyribonucleic acid that contains adenine arabinoside.
Biochemical pharmacology 1983;32(24):3849-52.
1983: Wisch J S; Griffin J D; Kufe D W
Response of preleukemic syndromes to continuous infusion of low-dose cytarabine.
The New England journal of medicine 1983;309(26):1599-602.
1983: Minden M; Major P; Griffin J; Wu A; Kufe D
Generation time of leukaemic blast progenitor cells.
Cell and tissue kinetics 1983;16(6):577-82.
1983: Kufe D W; Major P P; Munroe D; Egan M; Herrick D
Relationship between incorporation of 9-beta-D-arabinofuranosyladenine in L 1210 DNA and cytotoxicity.
Cancer research 1983;43(5):2000-4.
1983: Kufe D W; Scott P; Fram R; Major P
Biologic effect of 5-fluoro-2'-deoxyuridine incorporation in L1210 deoxyribonucleic acid.
Biochemical pharmacology 1983;32(8):1337-40.
1983: Colcher D; Zalutsky M; Kaplan W; Kufe D; Austin F; Schlom J
Radiolocalization of human mammary tumors in athymic mice by a monoclonal antibody.
Cancer research 1983;43(2):736-42.
1983: Kufe D W; Nadler L; Sargent L; Shapiro H; Hand P; Austin F; Colcher D; Schlom J
Biological behavior of human breast carcinoma-associated antigens expressed during cellular proliferation.
Cancer research 1983;43(2):851-7.
1983: Fram R; Major P; Egan E; Beardsley P; Rosenthal D; Kufe D
A phase I-II study of combination therapy with thymidine and cytosine arabinoside.
Cancer chemotherapy and pharmacology 1983;11(1):43-7.
1983: Fram R J; Egan E M; Kufe D W
Accumulation of leukemic cell DNA strand breaks with adriamycin and cytosine arabinoside.
Leukemia research 1983;7(2):243-9.
1983: Major P P; Agarwal R P; Kufe D W
Clinical pharmacology of arabinofuranosyladenine in combination with deoxycoformycin.
Cancer chemotherapy and pharmacology 1983;10(2):125-8.
1983: Colcher D; Hand P H; Wunderlich D; Nuti M; Teramoto Y A; Kufe D; Schlom J
Monoclonal antibodies to human mammary carcinoma associated antigens and their potential uses for diagnosis, prognosis, and therapy.
Laboratory and research methods in biology and medicine 1983;8():215-58.
1982: Rosowsky A; Abelson H T; Beardsley G P; Ensminger W D; Kufe D W; Steele G; Modest E J
Pharmacologic studies on the dibutyl and gamma-monobutyl esters of methotrexate in the rhesus monkey.
Cancer chemotherapy and pharmacology 1982;10(1):55-61.
1982: Herrick D J; Major P P; Kufe D W
Effect of methotrexate on incorporation and excision of 5-fluorouracil residues in human breast carcinoma DNA.
Cancer research 1982;42(12):5015-7.
1982: Griffin J; Munroe D; Major P; Kufe D
Induction of differentiation of human myeloid leukemia cells by inhibitors of DNA synthesis.
Experimental hematology 1982;10(9):774-81.
1982: Fram R J; Kufe D W
DNA strand breaks caused by inhibitors of DNA synthesis: 1-beta-D-arabinofuranosylcytosine and aphidicolin.
Cancer research 1982;42(10):4050-3.
1982: Major P P; Egan E M; Herrick D J; Kufe D W
Effect of ARA-C incorporation on deoxyribonucleic acid synthesis in cells.
Biochemical pharmacology 1982;31(18):2937-40.
1982: Agarwal R P; Major P P; Kufe D W
Simple and rapid high-performance liquid chromatographic method for analysis of nucleosides in biological fluids.
Journal of chromatography 1982;231(2):418-24.
1982: Weiss G R; McGovren J P; Schade D; Kufe D W
Phase I and pharmacological study of acivicin by 24-hour continuous infusion.
Cancer research 1982;42(9):3892-5.
1982: Major P P; Egan E; Herrick D; Kufe D W
5-Fluorouracil incorporation in DNA of human breast carcinoma cells.
Cancer research 1982;42(8):3005-9.
1982: Major P P; Egan E M; Herrick D; Kufe D W
Instability of (ara-C) DNA under alkaline conditions.
Biochemical pharmacology 1982;31(5):861-6.
1982: Weiss G R; Ervin T J; Meshad M W; Kufe D W
Phase II trial of combination therapy with continuous-infusion PALA and bolus-injection 5-FU.
Cancer treatment reports 1982;66(2):299-303.
1982: Weiss G R; Ervin T J; Meshad M W; Schade D; Branfman A R; Bruni R J; Chadwick M; Kufe D W
A phase I trial of combination therapy with continuous-infusion PALA and continuous-infusion 5-FU.
Cancer chemotherapy and pharmacology 1982;8(3):301-4.
1982: Major P P; Egan E M; Sargent L; Kufe D W
Modulation of 5-FU metabolism in human MCF-7 breast carcinoma cells.
Cancer chemotherapy and pharmacology 1982;8(1):87-91.
1982: Kufe D W; Major P P
Studies on the mechanism of action of cytosine arabinoside.
Medical and pediatric oncology 1982;10 Suppl 1():49-67.
1981: Kufe D W; Wick M M; Moschella S; Major P
Effect of high-dose thymidine infusions in patients with mycosis fungoides.
Cancer 1981;48(7):1513-6.
1981: Kufe D W; Major P P
5-Fluorouracil incorporation into human breast carcinoma RNA correlates with cytotoxicity.
The Journal of biological chemistry 1981;256(19):9802-5.
1981: Egan E M; Sargent L; Rosowsky A; Kufe D W
Rescue of thymidine cytotoxicity in L1210 ascites by elevated endogenous levels of deoxycytidine.
Cancer treatment reports 1981;65(9-10):853-60.
1981: Loh E; Kufe D W
Synergistic effects with inhibitors of de novo pyrimidine synthesis, acivicin, and N-(phosphonacetyl)-L-aspartic acid.
Cancer research 1981;41(9 Pt 1):3419-23.
1981: Kufe D W; Major P P; Egan E M; Loh E
5-Fluoro-2'-deoxyuridine incorporation in L1210 DNA.
The Journal of biological chemistry 1981;256(17):8885-8.
1981: Major P P; Sargent L; Egan E M; Kufe D W
Correlation of thymidine-enhanced incorporation of ara-C in deoxyribonucleic acid with increased cell kill.
Biochemical pharmacology 1981;30(16):2221-4.
1981: Major P P; Agarwal R P; Kufe D W
Clinical pharmacology of deoxycoformycin.
Blood 1981;58(1):91-6.
1981: Major P P; Egan E M; Beardsley G P; Minden M D; Kufe D W
Lethality of human myeloblasts correlates with the incorporation of arabinofuranosylcytosine into DNA.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(5):3235-9.
1981: Meshad M W; Ervin T J; Kufe D; Johnson R K; Blum R H; Frei E
Phase I trial of combination therapy with PALA and 5-FU.
Cancer treatment reports 1981;65(3-4):331-4.
1981: Rosowsky A; Wright J E; Steele G; Kufe D W
Thymidine 5'-O-pivaloate: evidence for prodrug action in the rat and rhesus monkey.
Cancer treatment reports 1981;65(1-2):93-9.
1981: Kufe D W; Egan E M
Enhancement of 5-fluorouracil incorporation into human lymphoblast ribonucleic acid.
Biochemical pharmacology 1981;30(2):129-33.
1981: Abelson H T; Kufe D W; Skarin A T; Major P; Ensminger W; Beardsley G P; Canellos G P
Treatment of central nervous system tumors with methotrexate.
Cancer treatment reports 1981;65 Suppl 1():137-40.
1981: Major P P; Agarwal R P; Kufe D W
Deoxycoformycin: neurological toxicity.
Cancer chemotherapy and pharmacology 1981;5(3):193-6.
1981: Major P P; Griffin J D; Minden M; Kufe D W
A blast subclone of the HL-60 human promyelocytic cell line.
Leukemia research 1981;5(4-5):429-30.
1980: Ervin T J; Blum R H; Meshad M W; Kufe D W; Johnson R K; Canellos G P
Phase I trial of N-(Phosphonacetyl)-L-aspartic acid (PALA).
Cancer treatment reports 1980;64(10-11):1067-71.
1980: Kufe D W; Wick M M; Abelson H T
Natural resistance to methotrexate in human melanomas.
The Journal of investigative dermatology 1980;75(4):357-9.
1980: Kufe D W; Major P P; Egan E M; Beardsley G P
Correlation of cytotoxicity with incorporation of ara-C into DNA.
The Journal of biological chemistry 1980;255(19):8997-900.
1980: Nadler L M; Stashenko P; Hardy R; Kaplan W D; Button L N; Kufe D W; Antman K H; Schlossman S F
Serotherapy of a patient with a monoclonal antibody directed against a human lymphoma-associated antigen.
Cancer research 1980;40(9):3147-54.
1980: Kufe D W; Beardsley P; Karp D; Parker L; Rosowsky A; Canellos G; Frei E
High-dose thymidine infusions in patients with leukemia and lymphoma.
Blood 1980;55(4):580-9.
1980: Kufe D W; Egan E M; Rosowsky A; Ensminger W; Frei E
Thymidine arrest and synchrony of cellular growth in vivo.
Cancer treatment reports 1980;64(12):1307-17.

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