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Nikolaus Kühn-Velten

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Christian Clajus; Gernot Beutel; W Nikolaus Kühn-Velten; Johan M Lorenzen; Daniel Pietsch; Julius J Schmidt; Jan T Kielstein
Cotrimoxazole plasma levels, dialyzer clearance and total removal by extended dialysis in a patient with acute kidney injury: risk of under-dosing using current dosing recommendations.
Ulrich Hammer; Rudolf Wegener; Horst Nizze; Gunther Wöhlke; Christine Kruse; Bernd Dworniczak; W Nikolaus Kühn-Velten; G F E Nöldge-Schomburg; Rainer Hofmockel; Ludwig Jonas
Sickle cell anemia: conclusions from a forensic case report of a young African woman who died after anesthesia.
H Kirchherr; W Nikolaus Kühn-Velten
Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: a multi-level, single-sample approach.

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2013: Christian Clajus; Gernot Beutel; W Nikolaus Kühn-Velten; Johan M Lorenzen; Daniel Pietsch; Julius J Schmidt; Jan T Kielstein
Cotrimoxazole plasma levels, dialyzer clearance and total removal by extended dialysis in a patient with acute kidney injury: risk of under-dosing using current dosing recommendations.
BMC pharmacology & toxicology 2013;14():19.
2006: Ulrich Hammer; Rudolf Wegener; Horst Nizze; Gunther Wöhlke; Christine Kruse; Bernd Dworniczak; W Nikolaus Kühn-Velten; G F E Nöldge-Schomburg; Rainer Hofmockel; Ludwig Jonas
Sickle cell anemia: conclusions from a forensic case report of a young African woman who died after anesthesia.
Ultrastructural pathology 2006;30(6):415-22.
2006: H Kirchherr; W Nikolaus Kühn-Velten
Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: a multi-level, single-sample approach.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2006;843(1):100-13.
2005: Klaus Rave; Sabine Flesch; W Nikolaus Kühn-Velten; Beate C Hompesch; Lutz Heinemann; Tim Heise
Enhancement of blood glucose lowering effect of a sulfonylurea when coadministered with an ACE inhibitor: results of a glucose-clamp study.
Diabetes/metabolism research and reviews 2005;21(5):459-64.
2005: Hartmut Kirchherr; W Nikolaus Kühn-Velten
HPLC-tandem mass spectrometric method for rapid quantification of dimethylarginines in human plasma.
Clinical chemistry 2005;51(1):249-52.
2002: W Nikolaus Kühn-Velten; H Genesius; K J Wiefels
Measurement of accidental urinary insulin loss from a dislocated intraperitoneal insulin catheter.
Diabetes & metabolism 2002;28(1):51-4.
2002: Jacqueline Heger; Axel Gödecke; Ulrich Flögel; Marc W Merx; Andrei Molojavyi; W Nikolaus Kühn-Velten; Jürgen Schrader
Cardiac-specific overexpression of inducible nitric oxide synthase does not result in severe cardiac dysfunction.
Circulation research 2002;90(1):93-9.
2000: W Nikolaus Kühn-Velten
Intracrinology and the local enzymatic control of hormone distribution and metabolism: dehydroepiandrosterone does not just act as a prohormone for androgens and estrogens.
European journal of clinical investigation 2000;30 Suppl 3():34-8.
1997: W Peter M Benten; P Ulrich; W Nikolaus Kühn-Velten; Hans-Werner Vohr; Frank Wunderlich
Testosterone-induced susceptibility to Plasmodium chabaudi malaria: persistence after withdrawal of testosterone.
The Journal of endocrinology 1997;153(2):275-81.
1997: W Nikolaus Kühn-Velten
Improvement of cytochrome P450c17 catalytic processivity as a novel mechanism to attenuate hormonal consequences of enzyme decay in the testes after a gonadotropin surge.
European journal of endocrinology / European Federation of Endocrine Societies 1997;136(4):438-43.
1997: J B Löhr; W Nikolaus Kühn-Velten
Protein phosphorylation changes ligand-binding efficiency of cytochrome P450c17 (CYP17) and accelerates its proteolytic degradation: putative relevance for hormonal regulation of CYP17 activity.
Biochemical and biophysical research communications 1997;231(2):403-8.
1997: W Nikolaus Kühn-Velten; Ulrich Pippirs
Novel connections between NADPH-induced lipid peroxidation and cytochrome P450 inactivation, and antioxidant and enzyme protective properties of estradiol in gonadal membranes.
Free radical research 1997;26(2):125-33.
1997: W Nikolaus Kühn-Velten
Effects of compatible solutes on mammalian cytochrome P450 stability.
Zeitschrift für Naturforschung. C, Journal of biosciences 1997;52(1-2):132-5.
1997: Horst Mossmann; W Peter M Benten; Chris Galanos; Marina A Freudenberg; W Nikolaus Kühn-Velten; H Reinauer; Frank Wunderlich
Dietary testosterone suppresses protective responsiveness to Plasmodium chabaudi malaria.
Life sciences 1997;60(11):839-48.
1996: W Nikolaus Kühn-Velten; J B Löhr
Ligand dependence of cytochrome P450c17 protection against proteolytic inactivation: structural, methodological and functional implications.
FEBS letters 1996;388(1):21-5.
1996: W Nikolaus Kühn-Velten
Rapid down-regulation of testicular androgen biosynthesis at increased environmental temperature is due to cytochrome P450c17 (CYP17) thermolability in Leydig cells, but not in endoplasmic reticulum membranes.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1996;104(3):243-9.
1995: M A Graf; V Pelzer; A Umlauf; W Nikolaus Kühn-Velten
Partial uncoupling of luteinizing hormone and prolactin pulse coincidence in hyperandrogenemic women.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 1995;9(3):239-45.
1993: W Peter M Benten; Frank Wunderlich; R Herrmann; W Nikolaus Kühn-Velten
Testosterone-induced compared with oestradiol-induced immunosuppression against Plasmodium chabaudi malaria.
The Journal of endocrinology 1993;139(3):487-94.
1993: W Nikolaus Kühn-Velten
Norharman (beta-carboline) as a potent inhibitory ligand for steroidogenic cytochromes P450 (CYP11 and CYP17).
European journal of pharmacology 1993;250(1):R1-3.
1993: M A Graf; Peter Bielfeld; W Distler; C Weiers; W Nikolaus Kühn-Velten
Pulsatile luteinizing hormone secretion pattern in hyperandrogenemic women.
Fertility and sterility 1993;59(4):761-7.
1993: W Nikolaus Kühn-Velten; M A Kempfle
Characterization of the hydrophobic interaction of steroids with endoplasmic reticulum membranes by quenching of 6,8(14)-bis-dehydro-17 alpha-hydroxyprogesterone fluorescence.
Biochimica et biophysica acta 1993;1145(2):185-90.
1992: W Nikolaus Kühn-Velten; M Lessmann
Ketoconazole inhibition of the bifunctional cytochrome P450c17 does not affect androgen formation from the endogenous lyase substrate. The catalytic site remains refractory in the course of intermediary hydroxyprogesterone processing.
Biochemical pharmacology 1992;44(12):2371-8.
1992: W Nikolaus Kühn-Velten
Integration of new regulatory strategies into the network of an endocrine control system: limitation of androgen secretion by rat testis is achieved by substrate-dependent modulation of P450XVII enzyme concentration and catalytic efficiency.
Andrologia 1992;24(2):109-11.
1991: Josef Abel; N de Ruiter; W Nikolaus Kühn-Velten
Comparative study on metallothionein induction in whole testicular tissue and isolated Leydig cells.
Archives of toxicology 1991;65(3):228-34.
1990: W Nikolaus Kühn-Velten
A microcompartmentation analysis of intermediate leakage response to substrate excess in a membrane-bound bifunctional enzyme: local control of hydroxyprogesterone channeling efficiency during cytochrome P450XVII-catalysed androgen biosynthesis.
Journal of cellular biochemistry 1990;43(2):149-59.
1990: W Nikolaus Kühn-Velten; A G Herzog; M R Müller
Acute effects of anticonvulsant drugs on gonadotropin-stimulated and precursor-supported androgen production in the rat testis.
European journal of pharmacology 1990;181(1-2):151-5.