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Allan Balmain
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28
Mao, Jian-Hua
15
Akhurst, Rosemary
15
Kemp, Christopher
11
Perez-Losada, Jesus
8
Wu, Di
6
DelRosario, Reyno
5
Nagase, Hiroki
5
Toland, Amanda E.
5
To, Minh
4
Portella, Giuseppe
4
Linardopoulos, Spiros
4
de Koning, John
4
Cai, Wei-Wen
4
Duffie, Elizabeth
3
Cano, Amparo
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All Publications
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2009: Quigley David; Balmain Allan
Systems genetics analysis of cancer susceptibility: from mouse models to humans.
Nature reviews. Genetics 2009;10(9):651-7.
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2009: Quigley David A; To Minh D; Pérez-Losada Jesús; Pelorosso Facundo G; Mao Jian-Hua; Nagase Hiroki; Ginzinger David G; Balmain Allan
Genetic architecture of mouse skin inflammation and tumour susceptibility.
Nature 2009;458(7237):505-8.
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2008: Mao J H; Wu D; DelRosario R; Castellanos A; Balmain A; Perez-Losada J
Atm heterozygosity does not increase tumor susceptibility to ionizing radiation alone or in a p53 heterozygous background.
Oncogene 2008;27(51):6596-600.
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2008: To Minh D; Wong Christine E; Karnezis Anthony N; Del Rosario Reyno; Di Lauro Roberto; Balmain Allan
Kras regulatory elements and exon 4A determine mutation specificity in lung cancer.
Nature genetics 2008;40(10):1240-4.
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2008: Mao Jian-Hua; Kim Il-Jin; Wu Di; Climent Joan; Kang Hio Chung; DelRosario Reyno; Balmain Allan
FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression.
Science (New York, N.Y.) 2008;321(5895):1499-502.
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2008: Chiaverotti Teresa; Couto Suzana S; Donjacour Annemarie; Mao Jian-Hua; Nagase Hiroki; Cardiff Robert D; Cunha Gerald R; Balmain Allan
Dissociation of epithelial and neuroendocrine carcinoma lineages in the transgenic adenocarcinoma of mouse prostate model of prostate cancer.
The American journal of pathology 2008;172(1):236-46.
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2007: Wei Guangwei; Ku Stephen; Ma Gene K; Saito Shin'ichi; Tang Amy A; Zhang Jiasheng; Mao Jian-Hua; Appella Ettore; Balmain Allan; Huang Eric J
HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(32):13040-5.
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2007: de Koning J P; Wakabayashi Y; Nagase H; Mao J-H; Balmain A
Convergence of congenic mapping and allele-specific alterations in tumors for the resolution of the Skts1 skin tumor susceptibility locus.
Oncogene 2007;26(28):4171-8.
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2007: Mao Jian-Hua; Wu Di; Perez-Losada Jesus; Jiang Tao; Li Qian; Neve Richard M; Gray Joe W; Cai Wei-Wen; Balmain Allan
Crosstalk between Aurora-A and p53: frequent deletion or downregulation of Aurora-A in tumors from p53 null mice.
Cancer cell 2007;11(2):161-73.
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2007: Wakabayashi Yuichi; Mao Jian-Hua; Brown Ken; Girardi Michael; Balmain Allan
Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice.
Nature 2007;445(7129):761-5.
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2006: To Minh D; Perez-Losada Jesus; Mao Jian-Hua; Hsu Jeff; Jacks Tyler; Balmain Allan
A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2LA2 mice.
Nature genetics 2006;38(8):926-30.
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2006: Mao Jian-Hua; Saunier Elise F; de Koning John P; McKinnon Margaret M; Higgins Mamie Nakijama; Nicklas Kathy; Yang Hai-Tao; Balmain Allan; Akhurst Rosemary J
Genetic variants of Tgfb1 act as context-dependent modifiers of mouse skin tumor susceptibility.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(21):8125-30.
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2006: Lacher Markus D; Tiirikainen Maarit I; Saunier Elise F; Christian Christine; Anders Mario; Oft Martin; Balmain Allan; Akhurst Rosemary J; Korn Wolfgang Michael
Transforming growth factor-beta receptor inhibition enhances adenoviral infectability of carcinoma cells via up-regulation of Coxsackie and Adenovirus Receptor in conjunction with reversal of epithelial-mesenchymal transition.
Cancer research 2006;66(3):1648-57.
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2005: Mao Jiang-Hua; Li Jiangzhen; Jiang Tao; Li Qian; Wu Di; Perez-Losada Jesus; DelRosario Reyno; Peterson Leif; Balmain Allan; Cai Wei-Wen
Genomic instability in radiation-induced mouse lymphoma from p53 heterozygous mice.
Oncogene 2005;24(53):7924-34.
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2005: To Minh D; Perez-Losada Jesus; Mao Jian-Hua; Balmain Allan
Crosstalk between Pten and Ras signaling pathways in tumor development.
Cell cycle (Georgetown, Tex.) 2005;4(9):1185-8.
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2005: Perez-Losada Jesus; Mao Jian-Hua; Balmain Allan
Control of genomic instability and epithelial tumor development by the p53-Fbxw7/Cdc4 pathway.
Cancer research 2005;65(15):6488-92.
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2005: Perez-Losada Jesus; Wu Di; DelRosario Reyno; Balmain Allan; Mao Jian-Hua
p63 and p73 do not contribute to p53-mediated lymphoma suppressor activity in vivo.
Oncogene 2005;24(35):5521-4.
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2005: Ewart-Toland Amanda; Dai Qi; Gao Yu-Tang; Nagase Hiroki; Dunlop Malcolm G; Farrington Susan M; Barnetson Rebecca A; Anton-Culver Hoda; Peel David; Ziogas Argyrios; Lin Dongxin; Miao Xiaoping; Sun Tong; Ostrander Elaine A; Stanford Janet L; Langlois Mariela; Chan June M; Yuan Jinwei; Harris Curtis C; Bowman Elise D; Clayman Gary L; Lippman Scott M; Lee J Jack; Zheng Wei; Balmain Allan
Aurora-A/STK15 T+91A is a general low penetrance cancer susceptibility gene: a meta-analysis of multiple cancer types.
Carcinogenesis 2005;26(8):1368-73.
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2005: Snijders Antoine M; Nowak Norma J; Huey Bing; Fridlyand Jane; Law Sindy; Conroy Jeffrey; Tokuyasu Taku; Demir Kubilay; Chiu Readman; Mao Jian-Hua; Jain Ajay N; Jones Steven J M; Balmain Allan; Pinkel Daniel; Albertson Donna G
Mapping segmental and sequence variations among laboratory mice using BAC array CGH.
Genome research 2005;15(2):302-11.
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2004: Dai Qi; Cai Qiu-Yin; Shu Xiao-Ou; Ewart-Toland Amanda; Wen Wan-Qing; Balmain Allan; Gao Yu-Tang; Zheng Wei
Synergistic effects of STK15 gene polymorphisms and endogenous estrogen exposure in the risk of breast cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(12):2065-70.
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2004: Mao Jian-Hua; Perez-Losada Jesus; Wu Di; Delrosario Reyno; Tsunematsu Ryosuke; Nakayama Keiichi I; Brown Ken; Bryson Sheila; Balmain Allan
Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene.
Nature 2004;432(7018):775-9.
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2004: Hsu Ssucheng J; Nagase Hiroki; Balmain Allan
Identification of Fetuin-B as a member of a cystatin-like gene family on mouse chromosome 16 with tumor suppressor activity.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2004;47(5):931-46.
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2004: Li Jiangzhen; Jiang Tao; Mao Jian-Hua; Balmain Allan; Peterson Leif; Harris Charles; Rao Pulivarthi H; Havlak Paul; Gibbs Richard; Cai Wei-Wen
Genomic segmental polymorphisms in inbred mouse strains.
Nature genetics 2004;36(9):952-4.
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2004: Fraga Mario F; Herranz Michel; Espada Jesús; Ballestar Esteban; Paz Maria F; Ropero Santiago; Erkek Emel; Bozdogan Onder; Peinado Héctor; Niveleau Alain; Mao Jian-Hua; Balmain Alan; Cano Amparo; Esteller Manel
A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors.
Cancer research 2004;64(16):5527-34.
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2004: Mao Jian-Hua; To Minh D; Perez-Losada Jesus; Wu Di; Del Rosario Reyno; Balmain Allan
Mutually exclusive mutations of the Pten and ras pathways in skin tumor progression.
Genes & development 2004;18(15):1800-5.
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2004: Ewart-Toland Amanda; Chan June M; Yuan Jinwei; Balmain Allan; Ma Jing
A gain of function TGFB1 polymorphism may be associated with late stage prostate cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(5):759-64.
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2004: Ewart-Toland Amanda; Balmain Allan
The genetics of cancer susceptibility: from mouse to man.
Toxicologic pathology 2004;32 Suppl 1():26-30.
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2004: Girardi Michael; Oppenheim David; Glusac Earl J; Filler Renata; Balmain Allan; Tigelaar Robert E; Hayday Adrian C
Characterizing the protective component of the alphabeta T cell response to transplantable squamous cell carcinoma.
The Journal of investigative dermatology 2004;122(3):699-706.
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2004: Balmain Allan; Akhurst Rosemary J
Cancer: dangerous liaisons.
Nature 2004;428(6980):271-2.
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2003: Mao Jian-Hua; Wu Di; Perez-Losada Jesus; Nagase Hiroki; DelRosario Reyno; Balmain Allan
Genetic interactions between Pten and p53 in radiation-induced lymphoma development.
Oncogene 2003;22(52):8379-85.
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2003: Hann Byron; Balmain Allan
Replication of an E1B 55-kilodalton protein-deficient adenovirus (ONYX-015) is restored by gain-of-function rather than loss-of-function p53 mutants.
Journal of virology 2003;77(21):11588-95.
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2003: Nagase Hiroki; Mao Jian-Hua; Balmain Allan
Allele-specific Hras mutations and genetic alterations at tumor susceptibility loci in skin carcinomas from interspecific hybrid mice.
Cancer research 2003;63(16):4849-53.
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2003: Ewart-Toland Amanda; Briassouli Paraskevi; de Koning John P; Mao Jian-Hua; Yuan Jinwei; Chan Florence; MacCarthy-Morrogh Lucy; Ponder Bruce A J; Nagase Hiroki; Burn John; Ball Sarah; Almeida Maria; Linardopoulos Spiros; Balmain Allan
Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human.
Nature genetics 2003;34(4):403-12.
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2003: Perez-Losada Jesus; Balmain Allan
Stem-cell hierarchy in skin cancer.
Nature reviews. Cancer 2003;3(6):434-43.
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2003: Balmain Allan; Gray Joe; Ponder Bruce
The genetics and genomics of cancer.
Nature genetics 2003;33 Suppl():238-44.
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2003: Mao Jian-Hua; Balmain Allan
Genomic approaches to identification of tumour-susceptibility genes using mouse models.
Current opinion in genetics & development 2003;13(1):14-9.
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2003: Yan Wen; Kitzes Galila; Dormishian Farid; Hawkins Lynda; Sampson-Johannes Adam; Watanabe Josh; Holt Jenny; Lee Vivian; Dubensky Thomas; Fattaey Ali; Hermiston Terry; Balmain Allan; Shen Yuqiao
Developing novel oncolytic adenoviruses through bioselection.
Journal of virology 2003;77(4):2640-50.
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2003: de Koning John P; Mao Jian-Hua; Balmain Allan
Novel approaches to identify low-penetrance cancer susceptibility genes using mouse models.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2003;163():19-27; discussion 264-6.
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2002: Psichari Eleni; Balmain Allan; Plows David; Zoumpourlis Vassilis; Pintzas Alexander
High activity of serum response factor in the mesenchymal transition of epithelial tumor cells is regulated by RhoA signaling.
The Journal of biological chemistry 2002;277(33):29490-5.
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2002: Oft Martin; Akhurst Rosemary J; Balmain Allan
Metastasis is driven by sequential elevation of H-ras and Smad2 levels.
Nature cell biology 2002;4(7):487-94.
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2002: Balmain Allan
Cancer: new-age tumour suppressors.
Nature 2002;417(6886):235-7.
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2002: Cai Wei-Wen; Mao Jian-Hua; Chow Chi-Wen; Damani Shamsha; Balmain Allan; Bradley Allan
Genome-wide detection of chromosomal imbalances in tumors using BAC microarrays.
Nature biotechnology 2002;20(4):393-6.
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2002: Balmain Allan
Cancer as a complex genetic trait: tumor susceptibility in humans and mouse models.
Cell 2002;108(2):145-52.
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2002: Bergo Martin O; Ambroziak Patricia; Gregory Cria; George Amanda; Otto James C; Kim Edward; Nagase Hiroki; Casey Patrick J; Balmain Allan; Young Stephen G
Absence of the CAAX endoprotease Rce1: effects on cell growth and transformation.
Molecular and cellular biology 2002;22(1):171-81.
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2001: Derynck R; Akhurst R J; Balmain A
TGF-beta signaling in tumor suppression and cancer progression.
Nature genetics 2001;29(2):117-29.
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2001: Papathoma A S; Zoumpourlis V; Balmain A; Pintzas A
Role of matrix metalloproteinase-9 in progression of mouse skin carcinogenesis.
Molecular carcinogenesis 2001;31(2):74-82.
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2001: Ganly I; Kim Y T; Hann B; Balmain A; Brown R
Replication and cytolysis of an E1B-attenuated adenovirus in drug-resistant ovarian tumour cells is associated with reduced apoptosis.
Gene therapy 2001;8(5):369-75.
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2001: Nagase H; Mao J H; de Koning J P; Minami T; Balmain A
Epistatic interactions between skin tumor modifier loci in interspecific (spretus/musculus) backcross mice.
Cancer research 2001;61(4):1305-8.
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2000: Petritsch C; Beug H; Balmain A; Oft M
TGF-beta inhibits p70 S6 kinase via protein phosphatase 2A to induce G(1) arrest.
Genes & development 2000;14(24):3093-101.
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2000: Linardopoulos S; Silva S; Klein G; Balmain A
Allele-specific loss or imbalance of chromosomes 9, 15, and 16 in B-cell tumors from interspecific F1 hybrid mice carrying Emu-c-myc or N-myc transgenes.
International journal of cancer. Journal international du cancer 2000;88(6):920-7.
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2000: Zoumpourlis V; Papassava P; Linardopoulos S; Gillespie D; Balmain A; Pintzas A
High levels of phosphorylated c-Jun, Fra-1, Fra-2 and ATF-2 proteins correlate with malignant phenotypes in the multistage mouse skin carcinogenesis model.
Oncogene 2000;19(35):4011-21.
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2000: Ganly I; Mautner V; Balmain A
Productive replication of human adenoviruses in mouse epidermal cells.
Journal of virology 2000;74(6):2895-9.
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2000: Frame S; Balmain A
Integration of positive and negative growth signals during ras pathway activation in vivo.
Current opinion in genetics & development 2000;10(1):106-13.
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1999: Nagase H; Mao J H; Balmain A
A subset of skin tumor modifier loci determines survival time of tumor-bearing mice.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):15032-7.
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1999: Frame S; Balmain A
Target genes and target cells in carcinogenesis.
British journal of cancer 1999;80 Suppl 1():28-33.
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1998: Frame S; Crombie R; Liddell J; Stuart D; Linardopoulos S; Nagase H; Portella G; Brown K; Street A; Akhurst R; Balmain A
Epithelial carcinogenesis in the mouse: correlating the genetics and the biology.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1998;353(1370):839-45.
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1998: Portella G; Cumming S A; Liddell J; Cui W; Ireland H; Akhurst R J; Balmain A
Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo: implications for tumor invasion.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(5):393-404.
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1998: Brown K; Strathdee D; Bryson S; Lambie W; Balmain A
The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted.
Current biology : CB 1998;8(9):516-24.
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1998: Mao J H; Lindsay K A; Balmain A; Wheldon T E
Stochastic modelling of tumorigenesis in p53 deficient mice.
British journal of cancer 1998;77(2):243-52.
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1997: Holden P R; McGuire B; Stoler A; Balmain A; Pitts J D
Changes in gap junctional intercellular communication in mouse skin carcinogenesis.
Carcinogenesis 1997;18(1):15-21.
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1996: Cui W; Fowlis D J; Bryson S; Duffie E; Ireland H; Balmain A; Akhurst R J
TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice.
Cell 1996;86(4):531-42.
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1996: Fowlis D J; Cui W; Johnson S A; Balmain A; Akhurst R J
Altered epidermal cell growth control in vivo by inducible expression of transforming growth factor beta 1 in the skin of transgenic mice.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(5):679-87.
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1996: Cano A; Gamallo C; Kemp C J; Benito N; Palacios J; Quintanilla M; Balmain A
Expression pattern of the cell adhesion molecules. E-cadherin, P-cadherin and alpha 6 beta 4 intergrin is altered in pre-malignant skin tumors of p53-deficient mice.
International journal of cancer. Journal international du cancer 1996;65(2):254-62.
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1996: Nagase H; Bryson S; Fee F; Balmain A
Multigenic control of skin tumour development in mice.
Ciba Foundation symposium 1996;197():156-68; discussion 168-80.
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1995: Brown K; Burns P A; Balmain A
Transgenic approaches to understanding the mechanisms of chemical carcinogenesis in mouse skin.
Toxicology letters 1995;82-83():123-30.
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1995: Linardopoulos S; Street A J; Quelle D E; Parry D; Peters G; Sherr C J; Balmain A
Deletion and altered regulation of p16INK4a and p15INK4b in undifferentiated mouse skin tumors.
Cancer research 1995;55(22):5168-72.
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1995: Bouffler S D; Kemp C J; Balmain A; Cox R
Spontaneous and ionizing radiation-induced chromosomal abnormalities in p53-deficient mice.
Cancer research 1995;55(17):3883-9.
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1995: Nagase H; Bryson S; Cordell H; Kemp C J; Fee F; Balmain A
Distinct genetic loci control development of benign and malignant skin tumours in mice.
Nature genetics 1995;10(4):424-9.
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1995: Cui W; Fowlis D J; Cousins F M; Duffie E; Bryson S; Balmain A; Akhurst R J
Concerted action of TGF-beta 1 and its type II receptor in control of epidermal homeostasis in transgenic mice.
Genes & development 1995;9(8):945-55.
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1995: Telliez J B; Plumb M; Balmain A; Bailleul B
Regulatory elements in the first intron of the mouse Ha-ras gene.
Molecular carcinogenesis 1995;12(3):137-45.
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1994: Cui W; Kemp C J; Duffie E; Balmain A; Akhurst R J
Lack of transforming growth factor-beta 1 expression in benign skin tumors of p53null mice is prognostic for a high risk of malignant conversion.
Cancer research 1994;54(22):5831-6.
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1994: Bremner R; Kemp C J; Balmain A
Induction of different genetic changes by different classes of chemical carcinogens during progression of mouse skin tumors.
Molecular carcinogenesis 1994;11(2):90-7.
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1994: Kemp C J; Wheldon T; Balmain A
p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis.
Nature genetics 1994;8(1):66-9.
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1994: Wright J H; McDonnell S; Portella G; Bowden G T; Balmain A; Matrisian L M
A switch from stromal to tumor cell expression of stromelysin-1 mRNA associated with the conversion of squamous to spindle carcinomas during mouse skin tumor progression.
Molecular carcinogenesis 1994;10(4):207-15.
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1994: Ah-See K W; Cooke T G; Pickford I R; Soutar D; Balmain A
An allelotype of squamous carcinoma of the head and neck using microsatellite markers.
Cancer research 1994;54(7):1617-21.
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1994: Merritt A J; Potten C S; Kemp C J; Hickman J A; Balmain A; Lane D P; Hall P A
The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice.
Cancer research 1994;54(3):614-7.
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1994: Brown K; Kemp C; Burns P; Balmain A
Importance of genetic alterations in tumour development.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1994;16():253-60.
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1994: Portella G; Liddell J; Crombie R; Haddow S; Clarke M; Stoler A B; Balmain A
Molecular mechanisms of invasion and metastasis during mouse skin tumour progression.
Invasion & metastasis 1994;14(1-6):7-16.
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1994: Kemp C J; Burns P A; Brown K; Nagase H; Balmain A
Transgenic approaches to the analysis of ras and p53 function in multistage carcinogenesis.
Cold Spring Harbor symposia on quantitative biology 1994;59():427-34.
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1993: Kemp C J; Fee F; Balmain A
Allelotype analysis of mouse skin tumors using polymorphic microsatellites: sequential genetic alterations on chromosomes 6, 7, and 11.
Cancer research 1993;53(24):6022-7.
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1993: Kemp C J; Donehower L A; Bradley A; Balmain A
Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.
Cell 1993;74(5):813-22.
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1993: Stoler A B; Stenback F; Balmain A
The conversion of mouse skin squamous cell carcinomas to spindle cell carcinomas is a recessive event.
The Journal of cell biology 1993;122(5):1103-17.
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1993: Fowlis D J; Balmain A
Oncogenes and tumour suppressor genes in transgenic mouse models of neoplasia.
European journal of cancer (Oxford, England : 1990) 1993;29A(4):638-45.
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1993: Brown K; Kemp C J; Burns P A; Stoler A B; Fowlis D J; Akhurst R J; Balmain A
Positive and negative growth control in multistage skin carcinogenesis.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1993;128():309-21.
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1993: Kemp C J; Bremner R; Balmain A
A revised map position for the Ha-ras gene on mouse chromosome 7: implications for analysis of genetic alterations in rodent tumors.
Molecular carcinogenesis 1993;7(3):147-50.
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1992: Burns P A; Balmain A
Potential therapeutic targets in multistep oncogenesis.
Seminars in cancer biology 1992;3(6):335-41.
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1992: Fowlis D J; Flanders K C; Duffie E; Balmain A; Akhurst R J
Discordant transforming growth factor beta 1 RNA and protein localization during chemical carcinogenesis of the skin.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1992;3(2):81-91.
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1992: Diaz-Guerra M; Haddow S; Bauluz C; Jorcano J L; Cano A; Balmain A; Quintanilla M
Expression of simple epithelial cytokeratins in mouse epidermal keratinocytes harboring Harvey ras gene alterations.
Cancer research 1992;52(3):680-7.
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1991: Burns P A; Kemp C J; Gannon J V; Lane D P; Bremner R; Balmain A
Loss of heterozygosity and mutational alterations of the p53 gene in skin tumours of interspecific hybrid mice.
Oncogene 1991;6(12):2363-9.
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1991: Burns P A; Jack A; Neilson F; Haddow S; Balmain A
Transformation of mouse skin endothelial cells in vivo by direct application of plasmid DNA encoding the human T24 H-ras oncogene.
Oncogene 1991;6(11):1973-8.
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1991: Quintanilla M; Haddow S; Jonas D; Jaffe D; Bowden G T; Balmain A
Comparison of ras activation during epidermal carcinogenesis in vitro and in vivo.
Carcinogenesis 1991;12(10):1875-81.
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1991: Haddow S; Fowlis D J; Parkinson K; Akhurst R J; Balmain A
Loss of growth control by TGF-beta occurs at a late stage of mouse skin carcinogenesis and is independent of ras gene activation.
Oncogene 1991;6(8):1465-70.
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1991: Buchmann A; Ruggeri B; Klein-Szanto A J; Balmain A
Progression of squamous carcinoma cells to spindle carcinomas of mouse skin is associated with an imbalance of H-ras alleles on chromosome 7.
Cancer research 1991;51(15):4097-101.
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1991: Burns P A; Bremner R; Balmain A
Genetic changes during mouse skin tumorigenesis.
Environmental health perspectives 1991;93():41-4.
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1991: Plumb M; Telliez J B; Fee F; Daubersies P; Bailleul B; Balmain A
Structural analysis of the mouse c-Ha-ras gene promoter.
Molecular carcinogenesis 1991;4(2):103-11.
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1991: Burns P A; Brown K; Bremner R; Clarke M; Balmain A
Molecular alterations in oncogenes or tumor suppressor genes during chemical carcinogenesis.
Progress in histochemistry and cytochemistry 1991;23(1-4):100-6.
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1991: Balmain A; Kemp C J; Burns P A; Stoler A B; Fowlis D J; Akhurst R J
Functional loss of tumour suppressor genes in multistage chemical carcinogenesis.
Princess Takamatsu symposia 1991;22():97-108.
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1990: Bailleul B; Surani M A; White S; Barton S C; Brown K; Blessing M; Jorcano J; Balmain A
Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter.
Cell 1990;62(4):697-708.
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1990: Bremner R; Balmain A
Genetic changes in skin tumor progression: correlation between presence of a mutant ras gene and loss of heterozygosity on mouse chromosome 7.
Cell 1990;61(3):407-17.
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1990: Parkinson K; Balmain A
Chalones revisited--a possible role for transforming growth factor beta in tumour promotion.
Carcinogenesis 1990;11(2):195-8.
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1990: Brown K; Buchmann A; Balmain A
Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumor progression.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(2):538-42.
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1990: Balmain A; Brown K; Bremner R
The interplay between ras oncogenes and tumor suppressor genes in experimental carcinogenesis.
Immunology series 1990;51():75-88.
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1989: Bailleul B; Brown K; Ramsden M; Akhurst R J; Fee F; Balmain A
Chemical induction of oncogene mutations and growth factor activity in mouse skin carcinogenesis.
Environmental health perspectives 1989;81():23-7.
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1989: Bailleul B; Brown K; Ramsden M; Fee F; Balmain A
Initiation of skin carcinogenesis can occur by induction of carcinogen-specific point mutations in the Harvey-ras gene.
Progress in clinical and biological research 1989;298():137-45.
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1989: Akhurst R; Bailleul B; Brown K; Ramsden M; Fee F; Balmain A
The action of oncogenes and growth factors in tumour initiation and promotion.
Carcinogenesis; a comprehensive survey 1989;11():243-55.
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1988: Balmain A; Brown K; Akhurst R J; Fee F M
Molecular analysis of chemical carcinogenesis in the skin.
The British journal of cancer. Supplement 1988;9():72-5.
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1988: Akhurst R J; Fee F; Balmain A
Localized production of TGF-beta mRNA in tumour promoter-stimulated mouse epidermis.
Nature 1988;331(6154):363-5.
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1988: Bailleul B; Lang J; Wilkie N; Balmain A
A human T24 Ha-ras cassette suitable for expression studies in eukaryotic cells.
Nucleic acids research 1988;16(1):359.
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1988: Brown K; Bailleul B; Ramsden M; Fee F; Krumlauf R; Balmain A
Isolation and characterization of the 5' flanking region of the mouse c-Harvey-ras gene.
Molecular carcinogenesis 1988;1(3):161-70.
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1988: Balmain A; Brown K
Oncogene activation in chemical carcinogenesis.
Advances in cancer research 1988;51():147-82.
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1986: Brown K; Quintanilla M; Ramsden M; Kerr I B; Young S; Balmain A
v-ras genes from Harvey and BALB murine sarcoma viruses can act as initiators of two-stage mouse skin carcinogenesis.
Cell 1986;46(3):447-56.
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1986: Quintanilla M; Brown K; Ramsden M; Balmain A
Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis.
Nature 1986;322(6074):78-80.
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1986: Balmain A; Quintanilla M; Brown K; Ramsden M
An approach to the molecular mechanisms of cancer induction.
The Journal of pathology 1986;149(1):3-8.
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1985: Kerr I B; Lee F D; Quintanilla M; Balmain A
Immunocytochemical demonstration of p21 ras family oncogene product in normal mucosa and in premalignant and malignant tumours of the colorectum.
British journal of cancer 1985;52(5):695-700.
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1985: Ramsden M; Cole G; Smith J; Balmain A
Differential methylation of the c-H-ras gene in normal mouse cells and during skin tumour progression.
The EMBO journal 1985;4(6):1449-54.
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1984: Balmain A; Ramsden M; Bowden G T; Smith J
Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas.
Nature 1984;307(5952):658-60.
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1983: Ramsden M; Loehren D; Balmain A
Identification of a rapidly labelled 350K histidine-rich protein in neonatal mouse epidermis.
Differentiation; research in biological diversity 1983;23(3):243-9.
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