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Anand Kumar

Research Profile

Disorders

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H1N1 Subtype Influenza A Virus

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Publications

TOP 3
Sheryl A Zelenitsky; Robert Ariano; Peter Dodek; Harris Iacovides; Anand Kumar; Yazdan Mirzanejad; Ethan Rubinstein
Vancomycin pharmacodynamics and survival in patients with methicillin-resistant Staphylococcus aureus-associated septic shock.
Duane J Funk; Eric Jacobsohn; Anand Kumar
Role of the venous return in critical illness and shock: part II-shock and mechanical ventilation.
Duane J Funk; Anand Kumar
Inhaled nitric oxide in patients with the acute respiratory distress syndrome secondary to the 2009 influenza A (H1N1) infection in Canada.

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All Publications

2013: Sheryl A Zelenitsky; Robert Ariano; Peter Dodek; Harris Iacovides; Anand Kumar; Yazdan Mirzanejad; Ethan Rubinstein
Vancomycin pharmacodynamics and survival in patients with methicillin-resistant Staphylococcus aureus-associated septic shock.
International journal of antimicrobial agents 2013;41(3):255-60.
2013: Duane J Funk; Eric Jacobsohn; Anand Kumar
Role of the venous return in critical illness and shock: part II-shock and mechanical ventilation.
Critical care medicine 2013;41(2):573-9.
2013: Duane J Funk; Anand Kumar
Inhaled nitric oxide in patients with the acute respiratory distress syndrome secondary to the 2009 influenza A (H1N1) infection in Canada.
Canadian journal of anaesthesia = Journal canadien d'anesthésie 2013;60(2):212-3.
2013: Duane J Funk; Eric Jacobsohn; Anand Kumar
The role of venous return in critical illness and shock-part I: physiology.
Critical care medicine 2013;41(1):255-62.
2012: Emily Rimmer; John Ronald; Satendra Sharma; Alexis F Turgeon; Kenneth Wood; Ryan Zarychanski; R Phillip Dellinger; Sandra Dial; Steve Doucette; David Gurka; Donald S Houston; Andreas Kramer; Anand Kumar; Aseem Kumar; John Marshall; Charles Penner
Activated protein C and septic shock: a propensity-matched cohort study*.
Critical care medicine 2012;40(11):2974-81.
2012: Shravan Kethireddy; Anand Kumar
Mortality due to septic shock following early, appropriate antibiotic therapy: can we do better?*.
Critical care medicine 2012;40(7):2228-9.
2011: Anand Kumar
Pandemic H1N1 influenza.
Journal of thoracic disease 2011;3(4):262-70.
2011: Anand Kumar
Early versus late oseltamivir treatment in severely ill patients with 2009 pandemic influenza A (H1N1): speed is life.
The Journal of antimicrobial chemotherapy 2011;66(5):959-63.
2011: Anand Kumar
Optimizing antimicrobial therapy in sepsis and septic shock.
Critical care nursing clinics of North America 2011;23(1):79-97.
2011: Clare Ramsey; Anand Kumar
H1N1: viral pneumonia as a cause of acute respiratory distress syndrome.
Current opinion in critical care 2011;17(1):64-71.
2011: Duane J Funk; Anand Kumar
Antimicrobial therapy for life-threatening infections: speed is life.
Critical care clinics 2011;27(1):53-76.
2010: Yoav Keynan; Jennifer Juno; Adrienne Meyers; T Blake Ball; Anand Kumar; Ethan Rubinstein; Keith R Fowke
Chemokine receptor 5 △32 allele in patients with severe pandemic (H1N1) 2009.
Emerging infectious diseases 2010;16(10):1621-2.
2010: Anand Kumar
Early antimicrobial therapy in severe sepsis and septic shock.
Current infectious disease reports 2010;12(5):336-44.
2010: Anand Kumar; Ryan Zarychanski; Bruce Light; Joseph Parrillo; Dennis Maki; Dave Simon; Denny Laporta; Steve Lapinsky; Paul Ellis; Yazdan Mirzanejad; Greg Martinka; Sean Keenan; Gordon Wood; Yaseen Arabi; Daniel Feinstein; Aseem Kumar; Peter Dodek; Laura Kravetsky; Steve Doucette
Early combination antibiotic therapy yields improved survival compared with monotherapy in septic shock: a propensity-matched analysis.
Critical care medicine 2010;38(9):1773-85.
2010: Anand Kumar; Nasia Safdar; Shravan Kethireddy; Dan Chateau
A survival benefit of combination antibiotic therapy for serious infections associated with sepsis and septic shock is contingent only on the risk of death: a meta-analytic/meta-regression study.
Critical care medicine 2010;38(8):1651-64.
2010: Titilayo Oluyomi-Obi; Lisa Avery; Carol Schneider; Anand Kumar; Stephen Lapinsky; Savas M Menticoglou; Ryan Zarychanski
Perinatal and maternal outcomes in critically ill obstetrics patients with pandemic H1N1 Influenza A.
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstétrique et gynécologie du Canada : JOGC 2010;32(5):443-7, 448-52.
2010: Negareh Mousavi; Andrew Czarnecki; Roien Ahmadie; Kanwal Kumar; Matthew Lytwyn; Anand Kumar; Davinder S Jassal
The utility of tissue Doppler imaging for the noninvasive determination of left ventricular filling pressures in patients with septic shock.
Journal of intensive care medicine 2010;25(3):163-7.
2010: Manish Sood; Claudio Rigatto; Ryan Zarychanski; Paul Komenda; Amy R Sood; Joe Bueti; Martina Reslerova; Dan Roberts; Julie Mojica; Anand Kumar
Acute kidney injury in critically ill patients infected with 2009 pandemic influenza A(H1N1): report from a Canadian Province.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2010;55(5):848-55.
2010: Duane J Funk; Faisal Siddiqui; Kim Wiebe; Russ R Miller; Edgar Bautista; Edgar Jimenez; Kimberley Webster; Anand Kumar
Practical lessons from the first outbreaks: clinical presentation, obstacles, and management strategies for severe pandemic (pH1N1) 2009 influenza pneumonitis.
Critical care medicine 2010;38(4 Suppl):e30-7.
2010: Clare D Ramsey; Duane Funk; Russell R Miller; Anand Kumar
Ventilator management for hypoxemic respiratory failure attributable to H1N1 novel swine origin influenza virus.
Critical care medicine 2010;38(4 Suppl):e58-65.
2010: Robert E Ariano; Daniel S Sitar; Sheryl A Zelenitsky; Ryan Zarychanski; Amarnath Pisipati; Stéphane Ahern; Salmaan Kanji; jordi rello; Anand Kumar
Enteric absorption and pharmacokinetics of oseltamivir in critically ill patients with pandemic (H1N1) influenza.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2010;182(4):357-63.
2010: Ryan Zarychanski; Tammy L Stuart; Anand Kumar; Steve Doucette; Lawrence Elliott; Joel Kettner; Frank Plummer
Correlates of severe disease in patients with 2009 pandemic influenza (H1N1) virus infection.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2010;182(3):257-64.
2009: Anand Kumar; Paul Ellis; Yaseen Arabi; Dan Roberts; Bruce Light; Joseph E Parrillo; Peter Dodek; Gordon Wood; Aseem Kumar; David Simon; Cheryl Peters; Muhammad Ahsan; Dan Chateau
Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock.
Chest 2009;136(5):1237-48.
2009: Anand Kumar
Optimizing antimicrobial therapy in sepsis and septic shock.
Critical care clinics 2009;25(4):733-51, viii.
2009: Duane Funk; Frank Sebat; Anand Kumar
A systems approach to the early recognition and rapid administration of best practice therapy in sepsis and septic shock.
Current opinion in critical care 2009;15(4):301-7.
2009: Duane J Funk; Joseph E Parrillo; Anand Kumar
Sepsis and septic shock: a history.
Critical care clinics 2009;25(1):83-101, viii.
2009: Rizwan A Manji; Kenneth E Wood; Anand Kumar
The history and evolution of circulatory shock.
Critical care clinics 2009;25(1):1-29, vii.
2009: Anand Kumar; Joseph E Parrillo
Preface.
Critical care clinics 2009;25(1):xiii-xiv.
2008: Sat Sharma; Anand Kumar
Antimicrobial management of sepsis and septic shock.
Clinics in chest medicine 2008;29(4):677-87, ix.
2008: Ryan Zarychanski; Steven Doucette; Dean Fergusson; Daniel Roberts; Donald S Houston; Satendra Sharma; Harlena Gulati; Anand Kumar
Early intravenous unfractionated heparin and mortality in septic shock.
Critical care medicine 2008;36(11):2973-9.
2008: Anand Kumar; Elizabeth Schupp; Eugene Bunnell; Amjad Ali; Barry Milcarek; Joseph E Parrillo
Cardiovascular response to dobutamine stress predicts outcome in severe sepsis and septic shock.
Critical care (London, England) 2008;12(2):R35.
2007: Anand Kumar; Bhanu Paladugu; Joel Mensing; Aseem Kumar; Joseph E Parrillo
Nitric oxide-dependent and -independent mechanisms are involved in TNF-alpha -induced depression of cardiac myocyte contractility.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;292(5):R1900-6.
2007: Anand Kumar; Aseem Kumar; Bhanu Paladugu; Joel Mensing; Joseph E Parrillo
Transforming growth factor-beta1 blocks in vitro cardiac myocyte depression induced by tumor necrosis factor-alpha, interleukin-1beta, and human septic shock serum.
Critical care medicine 2007;35(2):358-64.
2006: Anand Kumar; Daniel Roberts; Kenneth E Wood; Bruce Light; Joseph E Parrillo; Satendra Sharma; Robert Suppes; Daniel Feinstein; Sergio Zanotti; Leo Taiberg; David Gurka; Aseem Kumar; Mary Cheang
Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock.
Critical care medicine 2006;34(6):1589-96.
2006: Anand Kumar; Cameron Haery; Bhanu Paladugu; Aseem Kumar; Simon Symeoneides; Leo Taiberg; Jailan Osman; Gordon Trenholme; Steven M Opal; Roy Goldfarb; Joseph E Parrillo
The duration of hypotension before the initiation of antibiotic treatment is a critical determinant of survival in a murine model of Escherichia coli septic shock: association with serum lactate and inflammatory cytokine levels.
The Journal of infectious diseases 2006;193(2):251-8.
2005: Anand Kumar; Sergio Zanotti; Gene Bunnell; Kalim Habet; Ramon Añel; Alex Neumann; Mary Cheang; Charles A Dinarello; David L Cutler; Joseph E Parrillo
Interleukin-10 blunts the human inflammatory response to lipopolysaccharide without affecting the cardiovascular response.
Critical care medicine 2005;33(2):331-40.
2004: Anand Kumar; Eugene Bunnell; Melvyn Lynn; Ramon Anel; Kalim Habet; Alex Neumann; Joseph E Parrillo
Experimental human endotoxemia is associated with depression of load-independent contractility indices: prevention by the lipid a analogue E5531.
Chest 2004;126(3):860-7.
2004: Anand Kumar; Ramon Anel; Eugene Bunnell; Kalim Habet; Alex Neumann; David Wolff; Robert S Rosenson; Mary Cheang; Joseph E Parrillo
Effect of large volume infusion on left ventricular volumes, performance and contractility parameters in normal volunteers.
Intensive care medicine 2004;30(7):1361-9.
2004: Anand Kumar; Ramon Anel; Eugene Bunnell; Sergio Zanotti; Kalim Habet; Cameron Haery; Stephanie Marshall; Mary Cheang; Alex Neumann; Amjad Ali; Clifford Kavinsky; Joseph E Parrillo
Preload-independent mechanisms contribute to increased stroke volume following large volume saline infusion in normal volunteers: a prospective interventional study.
Critical care (London, England) 2004;8(3):R128-36.
2004: Bhanu Paladugu; Anand Kumar; Joseph E Parrillo; Sandy Der; Jailan Osman; Joel Mensing; Lisa Falvo; Xiulong Xu; Aseem Kumar
Bacterial DNA and RNA induce rat cardiac myocyte contraction depression in vitro.
Shock (Augusta, Ga.) 2004;21(4):364-9.
2004: Anand Kumar; Ramon Anel; Eugene Bunnell; Kalim Habet; Sergio Zanotti; Stephanie Marshall; Alex Neumann; Amjad Ali; Mary Cheang; Clifford Kavinsky; Joseph E Parrillo
Pulmonary artery occlusion pressure and central venous pressure fail to predict ventricular filling volume, cardiac performance, or the response to volume infusion in normal subjects.
Critical care medicine 2004;32(3):691-9.
2004: Leo Taiberg; Anand Kumar
Leukocyte lysozyme: a novel cause of septic myocardial depression?
Critical care medicine 2004;32(1):304-5.
2003: Rajit Pahwa; Anand Kumar
Persistent left superior vena cava: an intensivist's experience and review of the literature.
Southern medical journal 2003;96(5):528-9.
2003: Sat Sharma; Anand Kumar
Septic shock, multiple organ failure, and acute respiratory distress syndrome.
Current opinion in pulmonary medicine 2003;9(3):199-209.
2002: Olivier Court; Aseem Kumar; Joseph E Parrillo; Anand Kumar
Clinical review: Myocardial depression in sepsis and septic shock.
Critical care (London, England) 2002;6(6):500-8.
2002: Sanjay Manocha; Daniel Feinstein; Aseem Kumar; Anand Kumar
Novel therapies for sepsis: antiendotoxin therapies.
Expert opinion on investigational drugs 2002;11(12):1795-812.
2002: Sreenandh Krishnagopalan; Anand Kumar; Joseph E Parrillo; Anand Kumar
Myocardial dysfunction in the patient with sepsis.
Current opinion in critical care 2002;8(5):376-88.
2002: Sergio Zanotti; Anand Kumar; Anand Kumar
Cytokine modulation in sepsis and septic shock.
Expert opinion on investigational drugs 2002;11(8):1061-75.
2001: R L Añel; Anand Kumar
Experimental and emerging therapies for sepsis and septic shock.
Expert opinion on investigational drugs 2001;10(8):1471-85.
2001: Anand Kumar; A Krieger; S Symeoneides; A Kumar; Joseph E Parrillo
Myocardial dysfunction in septic shock: Part II. Role of cytokines and nitric oxide.
Journal of cardiothoracic and vascular anesthesia 2001;15(4):485-511.
2001: Anand Kumar; Cameron Haery; Joseph E Parrillo
Myocardial dysfunction in septic shock: Part I. Clinical manifestation of cardiovascular dysfunction.
Journal of cardiothoracic and vascular anesthesia 2001;15(3):364-76.
2000: Anand Kumar; Cameron Haery; Joseph E Parrillo
Myocardial dysfunction in septic shock.
Critical care clinics 2000;16(2):251-87.