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Rajiv Kumar

Research Profile

Genes & Molecular Sequences

Disorders

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Physiology

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Chemicals & Drugs

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Polymorphism, Single-Stranded Conformational

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Susanne Horn; Stephanie Kadel; Adina Figl; Christine Fischer; Andreas Gast; Kari Hemminki; Iris Moll; Eduardo Nagore; Sivaramakrishna Rachakonda; Dirk Schadendorf; Antje Sucker; Rajiv Kumar
TERT promoter mutations in familial and sporadic melanoma.
Simona Surdu; Marie Vahter; Michael S Bloom; Francis P Boscoe; David O Carpenter; Joëlle Févotte; Edward F Fitzgerald; Walter Goessler; Eugen Gurzau; Richard F Haase; Kvetoslava Koppova; Rajiv Kumar; Giovanni Leonardi; Peter Rudnai; Tony Fletcher
Occupational exposure to ultraviolet radiation and risk of non-melanoma skin cancer in a multinational European study.
Sivaramakrishna Rachakonda; Cosmeri Rizzato; Aldo Scarpa; Michaela Schanne; Jens Werner; Huaping Xie; John P Neoptolemos; Andrea S Bauer; Stefania Beghelli; Markus Büchler; Daniele Campa; Federico Canzian; Eithne Costello; Nathalia Giese; William Greenhalf; Anette Heller; Kari Hemminki; Jörg D Hoheisel; Rajiv Kumar
Somatic mutations in exocrine pancreatic tumors: association with patient survival.

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All Publications

2013: Susanne Horn; Stephanie Kadel; Adina Figl; Christine Fischer; Andreas Gast; Kari Hemminki; Iris Moll; Eduardo Nagore; Sivaramakrishna Rachakonda; Dirk Schadendorf; Antje Sucker; Rajiv Kumar
TERT promoter mutations in familial and sporadic melanoma.
Science (New York, N.Y.) 2013;339(6122):959-61.
2013: Simona Surdu; Marie Vahter; Michael S Bloom; Francis P Boscoe; David O Carpenter; Joëlle Févotte; Edward F Fitzgerald; Walter Goessler; Eugen Gurzau; Richard F Haase; Kvetoslava Koppova; Rajiv Kumar; Giovanni Leonardi; Peter Rudnai; Tony Fletcher
Occupational exposure to ultraviolet radiation and risk of non-melanoma skin cancer in a multinational European study.
PloS one 2013;8(4):e62359.
2013: Sivaramakrishna Rachakonda; Cosmeri Rizzato; Aldo Scarpa; Michaela Schanne; Jens Werner; Huaping Xie; John P Neoptolemos; Andrea S Bauer; Stefania Beghelli; Markus Büchler; Daniele Campa; Federico Canzian; Eithne Costello; Nathalia Giese; William Greenhalf; Anette Heller; Kari Hemminki; Jörg D Hoheisel; Rajiv Kumar
Somatic mutations in exocrine pancreatic tumors: association with patient survival.
PloS one 2013;8(4):e60870.
2013: Livia Maccioni; Eduardo Nagore; Dolores Planelles; Sivaramakrishna Rachakonda; Celia Requena; Dominique Scherer; Justo Lorenzo Bermejo; Kari Hemminki; Rajiv Kumar
Variants at chromosome 20 (ASIP locus) and melanoma risk.
International journal of cancer. Journal international du cancer 2013;132(1):42-54.
2012: A Martino; Enrico Orciuolo; M Petrini; R M Reis; R Ríos; J Sainz; A Stein; Janusz Szemraj; Z Szemraj-Rogucka; N Weinhold; Gabriele Buda; Daniele Campa; Federico Canzian; C Dumontet; R García-Sanz; F Gemignani; Hartmut Goldschmidt; Krzysztof Jamroziak; M Jurado; Rajiv Kumar; S Landi; H Marques; Anna Maria Rossi
Polymorphisms in xenobiotic transporters ABCB1, ABCG2, ABCC2, ABCC1, ABCC3 and multiple myeloma risk: a case-control study in the context of the International Multiple Myeloma rESEarch (IMMEnSE) consortium.
Leukemia 2012;26(6):1419-22.
2012: Giovanni Leonardi; Peter Rudnai; Simona Surdu; Marie Vahter; Walter Goessler; Eugen Gurzau; Kari Hemminki; Rupert Hough; Kvetoslava Koppova; Rajiv Kumar; Felicity Clemens; Tony Fletcher
Inorganic arsenic and basal cell carcinoma in areas of Hungary, Romania, and Slovakia: a case-control study.
Environmental health perspectives 2012;120(5):721-6.
2012: Romina E Lenci; P Sivaramakrishna Rachakonda; Dirk Schadendorf; Antje Sucker; Alexander N R Weber; Andreas Brandt; Andreas Gast; Kari Hemminki; Andriy V Kubarenko; Rajiv Kumar
Integrin genes and susceptibility to human melanoma.
Mutagenesis 2012;27(3):367-73.
2012: Alessio Naccarati; Barbara Pardini; V Polakova; Ludmila Vodickova; Kari Hemminki; Rajiv Kumar; Pavel Vodicka
Mutations and polymorphisms in TP53 gene--an overview on the role in colorectal cancer.
Mutagenesis 2012;27(2):211-8.
2012: Barbara Pardini; Pavel Vodicka; Alessio Naccarati; Rajiv Kumar
Gene expression variations: potentialities of master regulator polymorphisms in colorectal cancer risk.
Mutagenesis 2012;27(2):161-7.
2012: Romina Elizabeth Lenci; Iris Moll; Eduardo Nagore; Dolores Planelles; Celia Requena; Dirk Schadendorf; Antje Sucker; Justo Lorenzo Bermejo; Melanie Bevier; Andreas Brandt; Kari Hemminki; Rajiv Kumar
Influence of genetic variants in type I interferon genes on melanoma survival and therapy.
PloS one 2012;7(11):e50692.
2011: Cosmeri Rizzato; Peter Rudnai; Angelika Stein; Federico Canzian; Eugen Gurzau; Kari Hemminki; Kvetoslava Koppova; Rajiv Kumar; Daniele Campa
Interaction between functional polymorphic variants in cytokine genes, established risk factors and susceptibility to basal cell carcinoma of skin.
Carcinogenesis 2011;32(12):1849-54.
2011: Khelifa Arab; Rainer Claus; Allan V Espinosa; Andreas Gast; Thomas Hielscher; Joseph Po-Hsien Huang; Rajiv Kumar; Carl D Morrison; Matthew D Ringel; Dirk Schadendorf; Laura T Smith; Dieter Weichenhan; Christoph Plass
Epigenetic deregulation of TCF21 inhibits metastasis suppressor KISS1 in metastatic melanoma.
Carcinogenesis 2011;32(10):1467-73.
2011: Cosmeri Rizzato; Dominique Scherer; Peter Rudnai; Eugen Gurzau; Kvetoslava Koppova; Kari Hemminki; Federico Canzian; Rajiv Kumar; Daniele Campa
POMC and TP53 genetic variability and risk of basal cell carcinoma of skin: Interaction between host and genetic factors.
Journal of dermatological science 2011;63(1):47-54.
2011: Barbara Pardini; Rashmi B Prasad; Pavel Vodicka; Alessio Naccarati; Jan Novotny; Asta Forsti; Kari Hemminki; Rajiv Kumar; Justo Lorenzo Bermejo
5-Fluorouracil-based chemotherapy for colorectal cancer and MTHFR/MTRR genotypes.
British journal of clinical pharmacology 2011;72(1):162-3.
2011: Antonio Martorell-Calatayud; Eduardo Nagore; Rafael Botella-Estrada; Dominique Scherer; Celia Requena; Carlos Serra-Guillén; Beatriz Llombart; Onofre Sanmartin; Rajiv Kumar; Carlos Guillén
Defining fast-growing melanomas: reappraisal of epidemiological, clinical, and histological features.
Melanoma research 2011;21(2):131-8.
2011: Barbara Pardini; Rajiv Kumar; Alessio Naccarati; Rashmi B Prasad; Asta Forsti; Veronika Polakova; Ludmila Vodickova; Jan Novotny; Kari Hemminki; Pavel Vodicka
MTHFR and MTRR genotype and haplotype analysis and colorectal cancer susceptibility in a case-control study from the Czech Republic.
Mutation research 2011;721(1):74-80.
2011: Sabrina Angelini; Rajiv Kumar; Justo Lorenzo Bermejo; Francesca Maffei; Anna Barbieri; Francesca Graziosi; Fabio Carbone; Giorgio Cantelli-Forti; Francesco Saverio Violante; Kari Hemminki; Patrizia Hrelia
Exposure to low environmental levels of benzene: evaluation of micronucleus frequencies and S-phenylmercapturic acid excretion in relation to polymorphisms in genes encoding metabolic enzymes.
Mutation research 2011;719(1-2):7-13.
2011: Cosmeri Rizzato; Michaela Schanné; Afshan Siddiq; Jens Werner; Andrea Bauer; Markus W Büchler; Barbara Burwinkel; Daniele Campa; Eithne Costello; Nathalia Giese; William Greenhalf; Jörg D Hoheisel; Tim J Key; Kay-Tee Khaw; Rajiv Kumar; Justo Lorenzo-Bermejo; John P Neoptolemos; Sivaramakrishna Rachakonda; Federico Canzian
Pancreatic cancer susceptibility loci and their role in survival.
PloS one 2011;6(11):e27921.
2011: Andreas Gast; Kari Hemminki; Justo Lorenzo Bermejo; Andreas Brandt; Rainer Claus; Christoph Plass; Dirk Schadendorf; Antje Sucker; Alexander Weber; Marianne Weires; Rajiv Kumar
Association of inherited variation in Toll-like receptor genes with malignant melanoma susceptibility and survival.
PloS one 2011;6(9):e24370.
2011: Monika Hanova; Ludmila Vodickova; Radka Vaclavikova; Zdenek Smerhovsky; Rudolf Stetina; Pavel Hlavac; Alessio Naccarati; Jana Slyskova; Veronika Polakova; Pavel Soucek; Rajiv Kumar; Kari Hemminki; Pavel Vodicka
DNA damage, DNA repair rates and mRNA expression levels of cell cycle genes (TP53, p21(CDKN1A), BCL2 and BAX) with respect to occupational exposure to styrene.
Carcinogenesis 2011;32(1):74-9.
2010: Dominique Scherer; Sivaramakrishna Rachakonda; Sabrina Angelini; Franziska Mehnert; Antje Sucker; Friederike Egberts; Axel Hauschild; Kari Hemminki; Dirk Schadendorf; Rajiv Kumar
Association between the germline MC1R variants and somatic BRAF/NRAS mutations in melanoma tumors.
The Journal of investigative dermatology 2010;130(12):2844-8.
2010: Monika Hanova; Rudolf Stetina; Ludmila Vodickova; Radka Vaclavikova; Pavel Hlavac; Zdenek Smerhovsky; Alessio Naccarati; Veronika Polakova; Pavel Soucek; Miroslava Kuricova; Paola Manini; Rajiv Kumar; Kari Hemminki; Pavel Vodicka
Modulation of DNA repair capacity and mRNA expression levels of XRCC1, hOGG1 and XPC genes in styrene-exposed workers.
Toxicology and applied pharmacology 2010;248(3):194-200.
2010: Dominique Scherer; Rajiv Kumar
Genetics of pigmentation in skin cancer--a review.
Mutation research 2010;705(2):141-53.
2010: Adina Figl; Dominique Scherer; Eduardo Nagore; Justo Lorenzo Bermejo; Rafael Botella-Estrada; Andreas Gast; Ranjit K Thirumaran; Dolores Planelles; Kari Hemminki; Dirk Schadendorf; Rajiv Kumar
Single-nucleotide polymorphisms in DNA-repair genes and cutaneous melanoma.
Mutation research 2010;702(1):8-16.
2010: Andreas Gast; Dominique Scherer; Bowang Chen; Sandra Bloethner; Stephanie Melchert; Antje Sucker; Kari Hemminki; Dirk Schadendorf; Rajiv Kumar
Somatic alterations in the melanoma genome: a high-resolution array-based comparative genomic hybridization study.
Genes, chromosomes & cancer 2010;49(8):733-45.
2010: Rupert Lloyd Hough; Tony Fletcher; Giovanni Leonardi; Walter Goessler; Patrizia Gnagnarella; Felicity Clemens; Eugen Gurzau; Kvetoslava Koppova; Peter Rudnai; Rajiv Kumar; Marie Vahter
Lifetime exposure to arsenic in residential drinking water in Central Europe.
International archives of occupational and environmental health 2010;83(5):471-81.
2010: Rashmi Prasad; Fay J Hosking; Jayaram Vijayakrishnan; Elli Papaemmanuil; Rolf Koehler; Mel Greaves; Eamonn Sheridan; Andreas Gast; Sally E Kinsey; Tracy Lightfoot; Eve Roman; Malcolm Taylor; Kathy Pritchard-Jones; Martin Stanulla; Martin Schrappe; Claus R Bartram; Richard S Houlston; Rajiv Kumar; Kari Hemminki
Verification of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood.
Blood 2010;115(9):1765-7.
2010: Albert Picado; Shri Prakash Singh; Suman Rijal; Shyam Sundar; Bart Ostyn; François Chappuis; Surendra Uranw; Kamlesh Gidwani; Basudha Khanal; Madhukar Rai; Ishwari Sharma Paudel; Murari L Das; Rajiv Kumar; Pankaj Srivastava; Jean Claude Dujardin; Veerle Vanlerberghe; Elisabeth Wreford Andersen; Clive R Davies; Marleen Boelaert
Longlasting insecticidal nets for prevention of Leishmania donovani infection in India and Nepal: paired cluster randomised trial.
BMJ (Clinical research ed.) 2010;341():c6760.
2009: Sandra Bloethner; D Scherer; M Drechsel; Kari Hemminki; Rajiv Kumar
Malignant melanoma--a genetic overview.
Actas dermo-sifiliográficas 2009;100 Suppl 1():38-51.
2009: Dominique Scherer; Eduardo Nagore; Justo Lorenzo Bermejo; Adina Figl; Rafael Botella-Estrada; Ranjit K Thirumaran; Sabrina Angelini; Kari Hemminki; Dirk Schadendorf; Rajiv Kumar
Melanocortin receptor 1 variants and melanoma risk: a study of 2 European populations.
International journal of cancer. Journal international du cancer 2009;125(8):1868-75.
2009: Felipe Andres Castro; Katri Haimila; Inna Sareneva; Markus Schmitt; Justo Lorenzo; Nelli Kunkel; Rajiv Kumar; Asta Försti; Lennart Kjellberg; Göran Hallmans; Matti Lehtinen; Kari Hemminki; Michael Pawlita
Association of HLA-DRB1, interleukin-6 and cyclin D1 polymorphisms with cervical cancer in the Swedish population--a candidate gene approach.
International journal of cancer. Journal international du cancer 2009;125(8):1851-8.
2009: Liping Dai; Andreas Gast; Alexandra Horska; Martin Schrappe; Claus R Bartram; Kari Hemminki; Rajiv Kumar; Justo Lorenzo Bermejo
A case-control study of childhood acute lymphoblastic leukaemia and polymorphisms in the TGF-beta and receptor genes.
Pediatric blood & cancer 2009;52(7):819-23.
2009: V Polakova; Barbara Pardini; Alessio Naccarati; Stefano Landi; J Slyskova; J Novotny; Ludmila Vodickova; J L Bermejo; M Hanova; Z Smerhovsky; E Tulupova; Rajiv Kumar; Kari Hemminki; Pavel Vodicka
Genotype and haplotype analysis of cell cycle genes in sporadic colorectal cancer in the Czech Republic.
Human mutation 2009;30(4):661-8.
2009: Adina Figl; Dominique Scherer; Eduardo Nagore; Justo Lorenzo Bermejo; Elke Dickes; Ranjit K Thirumaran; Andreas Gast; Kari Hemminki; Rajiv Kumar; Dirk Schadendorf
Single nucleotide polymorphisms in DNA repair genes XRCC1 and APEX1 in progression and survival of primary cutaneous melanoma patients.
Mutation research 2009;661(1-2):78-84.
2008: E Tulupova; Rajiv Kumar; M Hanova; J Slyskova; Barbara Pardini; V Polakova; Alessio Naccarati; Ludmila Vodickova; J Novotny; J Halamkova; Kari Hemminki; Pavel Vodicka
Do polymorphisms and haplotypes of mismatch repair genes modulate risk of sporadic colorectal cancer?
Mutation research 2008;648(1-2):40-5.
2008: Charlotta Ryk; Michael Routledge; James M Allan; Christopher P Wild; Rajiv Kumar; Bo Lambert; Saimei Hou
Influence of DNA repair gene polymorphisms on the initial repair of MMS-induced DNA damage in human lymphocytes as measured by the alkaline comet assay.
Environmental and molecular mutagenesis 2008;49(9):669-75.
2008: Dominique Scherer; Justo Lorenzo Bermejo; Peter Rudnai; Eugen Gurzau; Kvetoslava Koppova; Kari Hemminki; Rajiv Kumar
MC1R variants associated susceptibility to basal cell carcinoma of skin: interaction with host factors and XRCC3 polymorphism.
International journal of cancer. Journal international du cancer 2008;122(8):1787-93.
2008: Barbara Pardini; Alessio Naccarati; J Novotny; Z Smerhovsky; Ludmila Vodickova; V Polakova; M Hanova; J Slyskova; Elena Tulupova; Rajiv Kumar; M Bortlik; Roberto Barale; Kari Hemminki; Pavel Vodicka
DNA repair genetic polymorphisms and risk of colorectal cancer in the Czech Republic.
Mutation research 2008;638(1-2):146-53.
2008: Sabrina Angelini; Rajiv Kumar; Fabio Carbone; Justo Lorenzo Bermejo; Francesca Maffei; Giorgio Cantelli-Forti; Kari Hemminki; Patrizia Hrelia
Inherited susceptibility to bleomycin-induced micronuclei: correlating polymorphisms in GSTT1, GSTM1 and DNA repair genes with mutagen sensitivity.
Mutation research 2008;638(1-2):90-7.
2007: Sandra Bloethner; Erna Snellman; Justo Lorenzo Bermejo; Eva Hiripi; Andreas Gast; Ranjit K Thirumaran; Ruth Wellenreuther; Kari Hemminki; Rajiv Kumar
Differential gene expression in melanocytic nevi with the V600E BRAF mutation.
Genes, chromosomes & cancer 2007;46(11):1019-27.
2007: Stefan Wilkening; Kari Hemminki; Peter Rudnai; Eugen Gurzau; Kvetoslava Koppova; Asta Försti; Rajiv Kumar
No association between MDM2 SNP309 promoter polymorphism and basal cell carcinoma of the skin.
The British journal of dermatology 2007;157(2):375-7.
2007: Anna-Lena Lindberg; Rajiv Kumar; Walter Goessler; Ranjit K Thirumaran; Eugen Gurzau; Kvetoslava Koppova; Peter Rudnai; Giovanni Leonardi; Tony Fletcher; Marie Vahter
Metabolism of low-dose inorganic arsenic in a central European population: influence of sex and genetic polymorphisms.
Environmental health perspectives 2007;115(7):1081-6.
2007: Adina Figl; Ranjit K Thirumaran; Selma Ugurel; Andreas Gast; Kari Hemminki; Rajiv Kumar; Dirk Schadendorf
Multiple melanomas after treatment for Hodgkin lymphoma in a non-Dutch p16-Leiden mutation carrier with 2 MC1R high-risk variants.
Archives of dermatology 2007;143(4):495-9.
2007: Andreas Gast; Justo Lorenzo Bermejo; T Flohr; M Stanulla; Barbara Burwinkel; M Schrappe; Claus R Bartram; Kari Hemminki; Rajiv Kumar
Folate metabolic gene polymorphisms and childhood acute lymphoblastic leukemia: a case-control study.
Leukemia 2007;21(2):320-5.
2007: Xuchen Li; Andreas Gast; Peter Rudnai; Eugen Gurzau; Kvetoslava Koppova; Kari Hemminki; Rajiv Kumar
ARLTS1 polymorphisms and basal cell carcinoma of the skin.
Hereditary cancer in clinical practice 2007;5(1):25-9.
2007: Somali Sanyal; Charlotta Ryk; Petra J De Verdier; Gunnar Steineck; Per Larsson; Erik Onelöv; Kari Hemminki; Rajiv Kumar
Polymorphisms in NQO1 and the clinical course of urinary bladder neoplasms.
Scandinavian journal of urology and nephrology 2007;41(3):182-90.
2007: Somali Sanyal; Petra J De Verdier; Gunnar Steineck; Per Larsson; Erik Onelöv; Kari Hemminki; Rajiv Kumar
Polymorphisms in XPD, XPC and the risk of death in patients with urinary bladder neoplasms.
Acta oncologica (Stockholm, Sweden) 2007;46(1):31-41.
2007: Selma Ugurel; Ranjit K Thirumaran; Sandra Bloethner; Andreas Gast; Antje Sucker; Jan Muller-Berghaus; Werner Rittgen; Kari Hemminki; Jürgen C Becker; Rajiv Kumar; Dirk Schadendorf
B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis.
PloS one 2007;2(2):e236.
2006: Stefan Wilkening; Kari Hemminki; Peter Rudnai; Eugen Gurzau; Kvetoslava Koppova; Rajiv Kumar; Asta Försti
Case-control study in basal cell carcinoma of the skin: single nucleotide polymorphisms in three interleukin promoters pre-analysed in pooled DNA.
The British journal of dermatology 2006;155(6):1139-44.
2006: Charlotta Ryk; Rajiv Kumar; Ranjit K Thirumaran; Sai-Mei Hou
Polymorphisms in the DNA repair genes XRCC1, APEX1, XRCC3 and NBS1, and the risk for lung cancer in never- and ever-smokers.
Lung cancer (Amsterdam, Netherlands) 2006;54(3):285-92.
2006: Roxana M Popovici; Nina K Betzler; Miriam S Krause; Man Luo; Julia Jauckus; Ariane Germeyer; Sandra Bloethner; Andreas Schlotterer; Rajiv Kumar; Thomas Strowitzki; Michael Von Wolff
Gene expression profiling of human endometrial-trophoblast interaction in a coculture model.
Endocrinology 2006;147(12):5662-75.
2006: Bernd Frank; Peter Meyer; Melanie Barbara Boettger; Kari Hemminki; Henrike Stapelmann; Andreas Gast; Christina Schmitt; Rajiv Kumar; Consolato Sergi; Barbara Burwinkel
ARLTS1 variants and melanoma risk.
International journal of cancer. Journal international du cancer 2006;119(7):1736-7.
2006: Charlotta Ryk; Rajiv Kumar; Somali Sanyal; Petra J Berggren de Verdier; Kari Hemminki; Per Larsson; Gunnar Steineck; Sai-Mei Hou
Influence of polymorphism in DNA repair and defence genes on p53 mutations in bladder tumours.
Cancer letters 2006;241(1):142-9.
2006: Ranjit K Thirumaran; Adina Thoelke; Selma Ugurel; Kari Hemminki; Dirk Schadendorf; Rajiv Kumar
Re: Association between endothelin receptor B nonsynonymous variants and melanoma risk.
Journal of the National Cancer Institute 2006;98(17):1252-3; author reply 1253.
2006: Sandra Bloethner; Kari Hemminki; Ranjit K Thirumaran; Bowang Chen; Jan Muller-Berghaus; Selma Ugurel; Dirk Schadendorf; Rajiv Kumar
Differences in global gene expression in melanoma cell lines with and without homozygous deletion of the CDKN2A locus genes.
Melanoma research 2006;16(4):297-307.
2006: Keith Hoek; Natalie Schlegel; Patricia Brafford; Antje Sucker; Selma Ugurel; Rajiv Kumar; Barbara L Weber; Katherine L Nathanson; David J Phillips; Meenhard Herlyn; Dirk Schadendorf; Reinhard Dummer
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2006;19(4):290-302.
2006: Ranjit K Thirumaran; Justo Lorenzo Bermejo; Peter Rudnai; Eugen Gurzau; Kvetoslava Koppova; Walter Goessler; Marie Vahter; Giovanni Leonardi; Felicity Clemens; Tony Fletcher; Kari Hemminki; Rajiv Kumar
Single nucleotide polymorphisms in DNA repair genes and basal cell carcinoma of skin.
Carcinogenesis 2006;27(8):1676-81.
2006: Shigeru Sakano; Rajiv Kumar; Per Larsson; Erik Onelöv; Jan Adolfsson; Gunnar Steineck; Kari Hemminki
A single-nucleotide polymorphism in the XPG gene, and tumour stage, grade, and clinical course in patients with nonmuscle-invasive neoplasms of the urinary bladder.
BJU international 2006;97(4):847-51.
2006: Stephan Wolf; Daniel Mertens; Armin Pscherer; Petra Schroeter; Dirk Winkler; Hermann-Josef Gröne; Christof Hofele; Kari Hemminki; Rajiv Kumar; Gunnar Steineck; Hartmut Döhner; Stephan Stilgenbauer; Peter Lichter
Ala228 variant of trail receptor 1 affecting the ligand binding site is associated with chronic lymphocytic leukemia, mantle cell lymphoma, prostate cancer, head and neck squamous cell carcinoma and bladder cancer.
International journal of cancer. Journal international du cancer 2006;118(7):1831-5.
2006: Anna-Lena Lindberg; Walter Goessler; Eugen Gurzau; Kvetoslava Koppova; Peter Rudnai; Rajiv Kumar; Tony Fletcher; Giovanni Leonardi; Katarina Slotova; Emilia Gheorghiu; Marie Vahter
Arsenic exposure in Hungary, Romania and Slovakia.
Journal of environmental monitoring : JEM 2006;8(1):203-8.
2005: Stefan Wilkening; Kari Hemminki; Ranjit K Thirumaran; Justo Lorenzo Bermejo; Stefan Bonn; Asta Försti; Rajiv Kumar
Determination of allele frequency in pooled DNA: comparison of three PCR-based methods.
BioTechniques 2005;39(6):853-8.
2005: Ranjit K Thirumaran; Andreas Gast; Thomas Flohr; Barbara Burwinkel; Claus Bartram; Kari Hemminki; Rajiv Kumar
MTHFR genetic polymorphisms and susceptibility to childhood acute lymphoblastic leukemia.
Blood 2005;106(7):2590-1; author reply 2591-2.
2005: Fabiola Festa; Rajiv Kumar; Somali Sanyal; Birgitte Undén; Linda Nordfors; Bengt Lindholm; Erna Snellman; Martin Schalling; Asta Försti; Kari Hemminki
Basal cell carcinoma and variants in genes coding for immune response, DNA repair, folate and iron metabolism.
Mutation research 2005;574(1-2):105-11.
2005: Sandra Bloethner; Bowang Chen; Kari Hemminki; Jan Muller-Berghaus; Selma Ugurel; Dirk Schadendorf; Rajiv Kumar
Effect of common B-RAF and N-RAS mutations on global gene expression in melanoma cell lines.
Carcinogenesis 2005;26(7):1224-32.
2005: Charlotta Ryk; Petra Berggren; Rajiv Kumar; Kari Hemminki; Per Larsson; Gunnar Steineck; Bo Lambert; Sai-Mei Hou
Influence of GSTM1, GSTT1, GSTP1 and NAT2 genotypes on the p53 mutational spectrum in bladder tumours.
International journal of cancer. Journal international du cancer 2005;113(5):761-8.
2004: Somali Sanyal; Fabiola Festa; Shigeru Sakano; Zhengzhong Zhang; Gunnar Steineck; Ulf Norming; Hans Wijkström; Per Larsson; Rajiv Kumar; Kari Hemminki
Polymorphisms in DNA repair and metabolic genes in bladder cancer.
Carcinogenesis 2004;25(5):729-34.
2004: Asta Försti; Sabrina Angelini; Fabiola Festa; Somali Sanyal; Zhenzhong Zhang; Ewa Grzybowska; Jolanta Pamula; Wioletta Pekala; Helena Zientek; Kari Hemminki; Rajiv Kumar
Single nucleotide polymorphisms in breast cancer.
Oncology reports 2004;11(4):917-22.
2004: Rajiv Kumar; Sabrina Angelini; Erna Snellman; Kari Hemminki
BRAF mutations are common somatic events in melanocytic nevi.
The Journal of investigative dermatology 2004;122(2):342-8.
2003: Rajiv Kumar; Sabrina Angelini; Kari Hemminki
Activating BRAF and N-Ras mutations in sporadic primary melanomas: an inverse association with allelic loss on chromosome 9.
Oncogene 2003;22(58):9217-24.
2003: Rajiv Kumar; Sabrina Angelini; Kamila Czene; Ilari Sauroja; Marjo Hahka-Kemppinen; Seppo Pyrhönen; Kari Hemminki
BRAF mutations in metastatic melanoma: a possible association with clinical outcome.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(9):3362-8.
2003: Shigeru Sakano; Petra Berggren; Rajiv Kumar; Gunnar Steineck; Jan Adolfsson; Erik Onelöv; Kari Hemminki; Per Larsson
Clinical course of bladder neoplasms and single nucleotide polymorphisms in the CDKN2A gene.
International journal of cancer. Journal international du cancer 2003;104(1):98-103.
2003: Rajiv Kumar; Sabrina Angelini; Kari Hemminki
Simultaneous detection of the exon 10 polymorphism and a novel intronic single base insertion polymorphism in the XPD gene using single strand conformation polymorphism.
Mutagenesis 2003;18(2):207-9.
2003: Rajiv Kumar; Lotta Höglund; Chunyan Zhao; Asta Försti; Erna Snellman; Kari Hemminki
Single nucleotide polymorphisms in the XPG gene: determination of role in DNA repair and breast cancer risk.
International journal of cancer. Journal international du cancer 2003;103(5):671-5.
2003: Petra Berggren; Rajiv Kumar; Shigeru Sakano; Liina Hemminki; Takashi Wada; Gunnar Steineck; Jan Adolfsson; Per Larsson; Ulf Norming; Hans Wijkström; Kari Hemminki
Detecting homozygous deletions in the CDKN2A(p16(INK4a))/ARF(p14(ARF)) gene in urinary bladder cancer using real-time quantitative PCR.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(1):235-42.
2002: Johanna Smeds; Petra Berggren; Xin Ma; Zhijian Xu; Kari Hemminki; Rajiv Kumar
Genetic status of cell cycle regulators in squamous cell carcinoma of the oesophagus: the CDKN2A (p16(INK4a) and p14(ARF) ) and p53 genes are major targets for inactivation.
Carcinogenesis 2002;23(4):645-55.
2001: Rajiv Kumar; Johanna Smeds; Petra Berggren; Oddbjørn Straume; Björn Rozell; Lars A Akslen; Kari Hemminki
A single nucleotide polymorphism in the 3'untranslated region of the CDKN2A gene is common in sporadic primary melanomas but mutations in the CDKN2B, CDKN2C, CDK4 and p53 genes are rare.
International journal of cancer. Journal international du cancer 2001;95(6):388-93.
2001: Johanna Smeds; Rajiv Kumar; Kari Hemminki
Polymorphic insertion of additional repeat within an area of direct 8 bp tandem repeats in the 5'-untranslated region of the p53R2 gene and cancer risk.
Mutagenesis 2001;16(6):547-50.
2001: P Berggren; Rajiv Kumar; G Steineck; M Ichiba; Kari Hemminki
Ethnic variation in genotype frequencies of a p53 intron 7 polymorphism.
Mutagenesis 2001;16(6):475-8.
2001: Johanna Smeds; M Nava; Rajiv Kumar; Kari Hemminki
A novel polymorphism (-88 C>A) in the 5' UTR of the p53R2 gene.
Human mutation 2001;17(1):82.
2000: X Ma; Qianren Jin; Asta Försti; Kari Hemminki; Rajiv Kumar
Single nucleotide polymorphism analyses of the human proliferating cell nuclear antigen (pCNA) and flap endonuclease (FEN1) genes.
International journal of cancer. Journal international du cancer 2000;88(6):938-42.
2000: Ilari Sauroja; J Smeds; Tatyana Vlaykova; Rajiv Kumar; Lauri Talve; Marjo Hahka-Kemppinen; Kari Punnonen; C T Jansèn; Kari Hemminki; Seppo Pyrhönen
Analysis of G(1)/S checkpoint regulators in metastatic melanoma.
Genes, chromosomes & cancer 2000;28(4):404-14.
2000: Susann Fält; Rajiv Kumar; Anders Wennborg; Aoy Tomita-Mitchell; William G Thilly; Bo Lambert
Identification of in vivo mutations in exon 5 of the human HPRT gene in a set of pooled T-cell mutants by constant denaturant capillary electrophoresis (CDCE).
Mutation research 2000;452(1):57-66.
2000: Johanna Smeds; Rajiv Kumar; Björn Rozell; Kari Hemminki
Increased frequency of LOH on chromosome 9 in sporadic primary melanomas is associated with increased patient age at diagnosis.
Mutagenesis 2000;15(3):257-60.
1999: Ingvar Eide; C Zhao; Rajiv Kumar; Kari Hemminki; K y Wu; James A Swenberg
Comparison of (32)P-postlabeling and high-resolution GC/MS in quantifying N7-(2-Hydroxyethyl)guanine adducts.
Chemical research in toxicology 1999;12(10):979-84.
1999: Rajiv Kumar; Johanna Smeds; B Lundh Rozell; Kari Hemminki
Loss of heterozygosity at chromosome 9p21 (INK4-p14ARF locus): homozygous deletions and mutations in the p16 and p14ARF genes in sporadic primary melanomas.
Melanoma research 1999;9(2):138-47.
1998: Rajiv Kumar; Ilari Sauroja; Kari Punnonen; C Jansen; Kari Hemminki
Selective deletion of exon 1 beta of the p19ARF gene in metastatic melanoma cell lines.
Genes, chromosomes & cancer 1998;23(3):273-7.
1998: Rajiv Kumar; B Lundh Rozell; J Louhelainen; Kari Hemminki
Mutations in the CDKN2A (p16INK4a) gene in microdissected sporadic primary melanomas.
International journal of cancer. Journal international du cancer 1998;75(2):193-8.
1997: Rajiv Kumar; Pavel Vodicka; Kimmo Peltonen; Kari Hemminki
32P-postlabelling analysis of isomeric 7-alkylguanine adducts of styrene oxide.
Carcinogenesis 1997;18(2):407-14.
1996: Rajiv Kumar; Pavel Vodicka; P Koivisto; Kimmo Peltonen; Kari Hemminki
32P-postlabelling of diastereomeric 7-alkylguanine adducts of butadiene monoepoxide.
Carcinogenesis 1996;17(6):1297-303.
1996: Kari Hemminki; Rajiv Kumar; Vladimir Bykov; J Louhelainen; Pavel Vodicka
Future research directions in the use of biomarkers.
Environmental health perspectives 1996;104 Suppl 3():459-64.
1996: Rajiv Kumar; Kari Hemminki
Separation of 7-methyl- and 7-(2-hydroxyethyl)-guanine adducts in human DNA samples using a combination of TLC and HPLC.
Carcinogenesis 1996;17(3):485-92.
1995: Rajiv Kumar; J S Hanekamp; J Louhelainen; K Burvall; A Onfelt; Kari Hemminki; W G Thilly
Separation of transforming amino acid-substituting mutations in codons 12, 13 and 61 the N-ras gene by constant denaturant capillary electrophoresis (CDCE).
Carcinogenesis 1995;16(11):2667-73.
1995: Rajiv Kumar; J Staffas; Asta Försti; Kari Hemminki
32P-postlabelling method for the detection of 7-alkylguanine adducts formed by the reaction of different 1,2-alkyl epoxides with DNA.
Carcinogenesis 1995;16(3):483-9.
1995: Vladimir Bykov; Rajiv Kumar; Asta Försti; Kari Hemminki
Analysis of UV-induced DNA photoproducts by 32P-postlabelling.
Carcinogenesis 1995;16(1):113-8.