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Shoen Kume

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Kahoko Umeda; Taiji Yamazoe; Yuichiro Higuchi; Kazuhiko Kume; Kohnosuke Mitani; Nobuaki Shiraki; Keiichiro Suzuki; Kumiko Tokieda; Shoen Kume
Albumin gene targeting in human embryonic stem cells and induced pluripotent stem cells with helper-dependent adenoviral vector to monitor hepatic differentiation.
Masateru Kataoka; Yuki Kawamuro; Kazuhiko Kume; Rika Miki; Daisuke Sakano; Nobuaki Shiraki; Takanori Yasukawa; Tetsu Yoshida; Shoen Kume
Recovery from diabetes in neonatal mice after a low-dose streptozotocin treatment.
Keiichi Katsumoto; Shoen Kume
The role of CXCL12-CXCR4 signaling pathway in pancreatic development.

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All Publications

2013: Kahoko Umeda; Taiji Yamazoe; Yuichiro Higuchi; Kazuhiko Kume; Kohnosuke Mitani; Nobuaki Shiraki; Keiichiro Suzuki; Kumiko Tokieda; Shoen Kume
Albumin gene targeting in human embryonic stem cells and induced pluripotent stem cells with helper-dependent adenoviral vector to monitor hepatic differentiation.
Stem cell research 2013;10(2):179-94.
2013: Masateru Kataoka; Yuki Kawamuro; Kazuhiko Kume; Rika Miki; Daisuke Sakano; Nobuaki Shiraki; Takanori Yasukawa; Tetsu Yoshida; Shoen Kume
Recovery from diabetes in neonatal mice after a low-dose streptozotocin treatment.
Biochemical and biophysical research communications 2013;430(3):1103-8.
2013: Keiichi Katsumoto; Shoen Kume
The role of CXCL12-CXCR4 signaling pathway in pancreatic development.
Theranostics 2013;3(1):11-7.
2012: Taro Ueno; Keita Endo; Kei Ito; Shoen Kume; Hiromu Tanimoto; Jun Tomita; Kazuhiko Kume
Identification of a dopamine pathway that regulates sleep and arousal in Drosophila.
Nature neuroscience 2012;15(11):1516-23.
2012: Kazuhiro Takahama; Jun Tomita; Taro Ueno; Masako Yamazaki; Shoen Kume; Kazuhiko Kume
Pan-neuronal knockdown of the c-Jun N-terminal Kinase (JNK) results in a reduction in sleep and longevity in Drosophila.
Biochemical and biophysical research communications 2012;417(2):807-11.
2012: Masako Yamazaki; Shoen Kume; Madoka Mitsuyoshi; Erina Sakamoto; Kazuhiro Takahama; Jun Tomita; Taro Ueno; Kazuhiko Kume
High calorie diet augments age-associated sleep impairment in Drosophila.
Biochemical and biophysical research communications 2012;417(2):812-6.
2012: Taro Ueno; Shoen Kume; Naoki Masuda; Kazuhiko Kume
Dopamine modulates the rest period length without perturbation of its power law distribution in Drosophila melanogaster.
PloS one 2012;7(2):e32007.
2012: Taro Ueno; Shoen Kume; Jun Tomita; Kazuhiko Kume
Dopamine modulates metabolic rate and temperature sensitivity in Drosophila melanogaster.
PloS one 2012;7(2):e31513.
2012: Rika Miki; Kazuya Murata; Shinya Oki; Tetsu Yoshida; Kazuhiko Kume; Shoen Kume
Fate maps of ventral and dorsal pancreatic progenitor cells in early somite stage mouse embryos.
Mechanisms of development 2012;128(11-12):597-609.
2011: Jun Tomita; Taro Ueno; Toshiro Aigaki; Yoshinori Aso; Shoen Kume; Madoka Mitsuyoshi; Yasuhiro Nakai; Hiromu Tanimoto; Kazuhiko Kume
Pan-neuronal knockdown of calcineurin reduces sleep in the fruit fly, Drosophila melanogaster.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(37):13137-46.
2011: Genta Nagae; Norio Nakatsuji; Aya Nonaka; Nobuaki Shiraki; Hidenobu Soejima; Hirofumi Suemori; Shuichi Tsutsumi; Shogo Yamamoto; Sayaka Yoshiba; Takanori Fujita; Masashi Fukayama; Takayuki Isagawa; Shumpei Ishikawa; Shoen Kume; Keisuke Matsusaka; Yutaka Midorikawa; Hiroyuki Aburatani
Tissue-specific demethylation in CpG-poor promoters during cellular differentiation.
Human molecular genetics 2011;20(14):2710-21.
2011: Shoen Kume
Xenopus embryos and ES cells as tools for studies of developmental biology.
Neurochemical research 2011;36(7):1280-5.
2011: Keiichi Katsumoto; Shoen Kume
Endoderm and mesoderm reciprocal signaling mediated by CXCL12 and CXCR4 regulates the migration of angioblasts and establishes the pancreatic fate.
Development (Cambridge, England) 2011;138(10):1947-55.
2011: Akira Matsuo; Tetsu Yoshida; Takanori Yasukawa; Rika Miki; Kazuhiko Kume; Shoen Kume
Epiplakin1 is expressed in the cholangiocyte lineage cells in normal liver and adult progenitor cells in injured liver.
Gene expression patterns : GEP 2011;11(3-4):255-62.
2011: Yuichiro Higuchi; Nobuaki Shiraki; Shoen Kume
In vitro models of pancreatic differentiation using embryonic stem or induced pluripotent stem cells.
Congenital anomalies 2011;51(1):21-5.
2011: Takayuki Isagawa; Shumpei Ishikawa; Shoen Kume; Genta Nagae; Noriko Sato; Nobuaki Shiraki; Takanori Fujita; Hiroyuki Aburatani
DNA methylation profiling of embryonic stem cell differentiation into the three germ layers.
PloS one 2011;6(10):e26052.
2011: Nobuaki Shiraki; Taiji Yamazoe; Kazuhiko Kume; Katsumi Mochitate; Keiko Ohgomori; Zeng Qin; Shoen Kume
Efficient differentiation of embryonic stem cells into hepatic cells in vitro using a feeder-free basement membrane substratum.
PloS one 2011;6(8):e24228.
2011: Soichiro Ogaki; Seiko Harada; Nobuaki Shiraki; Kazuhiko Kume; Shoen Kume
An expression profile analysis of ES cell-derived definitive endodermal cells and Pdx1-expressing cells.
BMC developmental biology 2011;11():13.
2010: Yuichiro Higuchi; Nobuaki Shiraki; Keitaro Yamane; Zeng Qin; Katsumi Mochitate; Kimi Araki; Takafumi Senokuchi; Kazuya Yamagata; Manami Hara; Kazuhiko Kume; Shoen Kume
Synthesized basement membranes direct the differentiation of mouse embryonic stem cells into pancreatic lineages.
Journal of cell science 2010;123(Pt 16):2733-42.
2010: Nobuaki Shiraki; Seiko Harada; Soichiro Ogaki; Kazuhiko Kume; Shoen Kume
Identification of DAF1/CD55, a novel definitive endoderm marker.
Cell structure and function 2010;35(2):73-80.
2010: Tetsu Yoshida; Xiaoli Guo; Kazuhiko Namekata; Yoshinori Mitamura; Shoen Kume; Takayuki Harada
Expression of Epiplakin1 in the developing and adult mouse retina.
Japanese journal of ophthalmology 2010;54(1):85-8.
2010: Keiichi Katsumoto; Nobuaki Shiraki; Rika Miki; Shoen Kume
Embryonic and adult stem cell systems in mammals: ontology and regulation.
Development, growth & differentiation 2010;52(1):115-29.
2009: Kumi Matsuura; Keiichi Katsumoto; Kimiko Fukuda; Kazuhiko Kume; Shoen Kume
Conserved origin of the ventral pancreas in chicken.
Mechanisms of development 2009;126(10):817-27.
2009: Keiichi Katsumoto; Kimiko Fukuda; Wataru Kimura; Kenji Shimamura; Sadao Yasugi; Shoen Kume
Origin of pancreatic precursors in the chick embryo and the mechanism of endoderm regionalization.
Mechanisms of development 2009;126(7):539-51.
2009: Tetsu Yoshida; Kazuya Murata; Nobuaki Shiraki; Kazuhiko Kume; Shoen Kume
Analysis of gene expressions of embryonic stem-derived Pdx1-expressing cells: implications of genes involved in pancreas differentiation.
Development, growth & differentiation 2009;51(4):463-72.
2009: Nobuaki Shiraki; Yuichiro Higuchi; Seiko Harada; Kahoko Umeda; Takayuki Isagawa; Hiroyuki Aburatani; Kazuhiko Kume; Shoen Kume
Differentiation and characterization of embryonic stem cells into three germ layers.
Biochemical and biophysical research communications 2009;381(4):694-9.
2008: Nobuaki Shiraki; Kahoko Umeda; Naomi Sakashita; Motohiro Takeya; Kazuhiko Kume; Shoen Kume
Differentiation of mouse and human embryonic stem cells into hepatic lineages.
Genes to cells : devoted to molecular & cellular mechanisms 2008;13(7):731-46.
2008: Tetsu Yoshida; Nobuaki Shiraki; Hideo Baba; Mizuki Goto; Sakuhei Fujiwara; Kazuhiko Kume; Shoen Kume
Expression patterns of epiplakin1 in pancreas, pancreatic cancer and regenerating pancreas.
Genes to cells : devoted to molecular & cellular mechanisms 2008;13(7):667-78.
2008: Nobuaki Shiraki; Tetsu Yoshida; Kimi Araki; Akihiro Umezawa; Yuichiro Higuchi; Hideo Goto; Kazuhiko Kume; Shoen Kume
Guided differentiation of embryonic stem cells into Pdx1-expressing regional-specific definitive endoderm.
Stem cells (Dayton, Ohio) 2008;26(4):874-85.
2007: Shoen Kume
[Turning ES cells into tissue stem cells of endodermal lineages].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2007;52(7):796-800.
2007: Tadashi Sugiki; Taro Uyama; Masashi Toyoda; Hideo Morioka; Shoen Kume; Kenji Miyado; Kenji Matsumoto; Hirohisa Saito; Noriyuki Tsumaki; Yoriko Takahashi; Yoshiaki Toyama; Akihiro Umezawa
Hyaline cartilage formation and enchondral ossification modeled with KUM5 and OP9 chondroblasts.
Journal of cellular biochemistry 2007;100(5):1240-54.
2007: Shoen Kume; Hideki Taniguchi
[Prospects for stem cell biology of the pancreas].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2007;52(2):139-44.
2006: Shoen Kume; Nobuaki Shiraki
[Pancreatic development and stem cell-based regenerative medicine].
Rinsho byori. The Japanese journal of clinical pathology 2006;54(4):386-92.
2005: Kazuhiko Kume; Shoen Kume; Sang Ki Park; Jay Hirsh; F Rob Jackson
Dopamine is a regulator of arousal in the fruit fly.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(32):7377-84.
2005: Shoen Kume
Stem-cell-based approaches for regenerative medicine.
Development, growth & differentiation 2005;47(6):393-402.
2005: Shoen Kume
The molecular basis and prospects in pancreatic development.
Development, growth & differentiation 2005;47(6):367-74.
2005: Masaki Ohmuraya; Masahiko Hirota; Masatake Araki; Noboru Mizushima; Makoto Matsui; Takao Mizumoto; Kyoko Haruna; Shoen Kume; Motohiro Takeya; Michio Ogawa; Kimi Araki; Ken-ichi Yamamura
Autophagic cell death of pancreatic acinar cells in serine protease inhibitor Kazal type 3-deficient mice.
Gastroenterology 2005;129(2):696-705.
2005: Nobuaki Shiraki; Cheng-Jung Lai; Yosuke Hishikari; Shoen Kume
TGF-beta signaling potentiates differentiation of embryonic stem cells to Pdx-1 expressing endodermal cells.
Genes to cells : devoted to molecular & cellular mechanisms 2005;10(6):503-16.
2005: Shoko Kodama; Tetsushi Toyonaga; Tatsuya Kondo; Kazuya Matsumoto; Kaku Tsuruzoe; Junji Kawashima; Hideo Goto; Kazuhiko Kume; Shoen Kume; Michiharu Sakakida; Eiichi Araki
Enhanced expression of PDX-1 and Ngn3 by exendin-4 during beta cell regeneration in STZ-treated mice.
Biochemical and biophysical research communications 2005;327(4):1170-8.
2003: Takeo Saneyoshi; Shoen Kume; Katsuhiko Mikoshiba
Calcium/calmodulin-dependent protein kinase I in Xenopus laevis.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2003;134(3):499-507.
2003: Jayaraj Rajagopal; William J Anderson; Shoen Kume; Olga I Martinez; Douglas A Melton
Insulin staining of ES cell progeny from insulin uptake.
Science (New York, N.Y.) 2003;299(5605):363.
2002: Takeo Saneyoshi; Shoen Kume; Yoshiharu Amasaki; Katsuhiko Mikoshiba
The Wnt/calcium pathway activates NF-AT and promotes ventral cell fate in Xenopus embryos.
Nature 2002;417(6886):295-9.
2000: Takeo Saneyoshi; Shoen Kume; T Natsume; Katsuhiko Mikoshiba
Molecular cloning and expression profile of Xenopus calcineurin A subunit(1).
Biochimica et biophysica acta 2000;1499(1-2):164-170.
2000: Shoen Kume; takafumi inoue; Katsuhiko Mikoshiba
Galphas family G proteins activate IP(3)-Ca(2+) signaling via gbetagamma and transduce ventralizing signals in Xenopus.
Developmental biology 2000;226(1):88-103.
2000: Shoen Kume; Takeo Saneyoshi; Katsuhiko Mikoshiba
Desensitization of IP3-induced Ca2+ release by overexpression of a constitutively active Gqalpha protein converts ventral to dorsal fate in Xenopus early embryos.
Development, growth & differentiation 2000;42(4):327-35.
1999: Shoen Kume
Role of the inositol 1,4,5-trisphosphate receptor in early embryonic development.
Cellular and molecular life sciences : CMLS 1999;56(3-4):296-304.
1997: Shoen Kume; Akihiko Muto; takafumi inoue; K Suga; H Okano; Katsuhiko Mikoshiba
Role of inositol 1,4,5-trisphosphate receptor in ventral signaling in Xenopus embryos.
Science (New York, N.Y.) 1997;278(5345):1940-3.
1997: Shoen Kume; Akihiko Muto; H Okano; Katsuhiko Mikoshiba
Developmental expression of the inositol 1,4,5-trisphosphate receptor and localization of inositol 1,4,5-trisphosphate during early embryogenesis in Xenopus laevis.
Mechanisms of development 1997;66(1-2):157-68.
1997: Hisashi Umemori; takafumi inoue; Shoen Kume; N Sekiyama; M Nagao; Hironori Itoh; S Nakanishi; Katsuhiko Mikoshiba; Tadashi Yamamoto
Activation of the G protein Gq/11 through tyrosine phosphorylation of the alpha subunit.
Science (New York, N.Y.) 1997;276(5320):1878-81.
1997: Shoen Kume; A Yamamoto; TAKANARI INOUE; Akihiko Muto; Hideyuki Okano; Katsuhiko Mikoshiba
Developmental expression of the inositol 1,4,5-trisphosphate receptor and structural changes in the endoplasmic reticulum during oogenesis and meiotic maturation of Xenopus laevis.
Developmental biology 1997;182(2):228-39.