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Ty Adams

Research Profile

Chemicals & Drugs

Procedures

X Ray Crystallography

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Protein Binding

Physiology

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Publications

TOP 3
Wei Li; Daniel J D Johnson; Ty E Adams; Nicola Pozzi; Vincenzo De Filippis; James A Huntington
Thrombin inhibition by serpins disrupts exosite II.
Ty E Adams; Wei Li; James A Huntington
Molecular basis of thrombomodulin activation of slow thrombin.
Wei Li; Ty E Adams; Jyoti Nangalia; Charles T Esmon; James A Huntington
Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex.

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All Publications

2010: Wei Li; Daniel J D Johnson; Ty E Adams; Nicola Pozzi; Vincenzo De Filippis; James A Huntington
Thrombin inhibition by serpins disrupts exosite II.
The Journal of biological chemistry 2010;285(49):38621-9.
2009: Ty E Adams; Wei Li; James A Huntington
Molecular basis of thrombomodulin activation of slow thrombin.
Journal of thrombosis and haemostasis : JTH 2009;7(10):1688-95.
2008: Wei Li; Ty E Adams; Jyoti Nangalia; Charles T Esmon; James A Huntington
Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(12):4661-6.
2007: Wei Li; Ty E Adams; Margareta Kjellberg; Johan Stenflo; James A Huntington
Structure of native protein C inhibitor provides insight into its multiple functions.
The Journal of biological chemistry 2007;282(18):13759-68.
2006: Ty E Adams; James A Huntington
Thrombin-cofactor interactions: structural insights into regulatory mechanisms.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(8):1738-45.
2006: Daniel J D Johnson; Wei Li; Ty E Adams; James A Huntington
Antithrombin-S195A factor Xa-heparin structure reveals the allosteric mechanism of antithrombin activation.
The EMBO journal 2006;25(9):2029-37.
2005: Daniel J D Johnson; Ty E Adams; Wei Li; James A Huntington
Crystal structure of wild-type human thrombin in the Na+-free state.
The Biochemical journal 2005;392(Pt 1):21-8.
2004: Ty E Adams; Matthew F Hockin; Kenneth G Mann; Stephen J Everse
The crystal structure of activated protein C-inactivated bovine factor Va: Implications for cofactor function.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(24):8918-23.
2004: Peter J Halbrooks; Anne Mason; Ty E Adams; Sara K Briggs; Stephen J Everse
The oxalate effect on release of iron from human serum transferrin explained.
Journal of molecular biology 2004;339(1):217-26.
2003: Ty E Adams; Stephen J Everse; Kenneth G Mann
Predicting the pharmacology of thrombin inhibitors.
Journal of thrombosis and haemostasis : JTH 2003;1(5):1024-7.
2003: Ty E Adams; Anne Mason; Qing-Yu He; Peter J Halbrooks; Sara K Briggs; Valerie C Smith; Ross T A MacGillivray; Stephen J Everse
The position of arginine 124 controls the rate of iron release from the N-lobe of human serum transferrin. A structural study.
The Journal of biological chemistry 2003;278(8):6027-33.
2001: Anne Mason; Qing-Yu He; Ty E Adams; Dmitry R Gumerov; Igor A Kaltashov; V Nguyen; Ross T A MacGillivray
Expression, purification, and characterization of recombinant nonglycosylated human serum transferrin containing a C-terminal hexahistidine tag.
Protein expression and purification 2001;23(1):142-50.