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Jerzy Kupiec-Weglinski

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Disorders

Reperfusion Injury

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Publications

TOP 3
Shen Xiuda; Wang Yue; Gao Feng; Ren Feng; Busuttil Ronald W; Kupiec-Weglinski Jerzy W; Zhai Yuan
CD4 T cells promote tissue inflammation via CD40 signaling without de novo activation in a murine model of liver ischemia/reperfusion injury.
Ke Bibo; Shen Xiu-Da; Gao Feng; Qiao Bo; Ji Haofeng; Busuttil Ronald W; Volk Hans-Dieter; Kupiec-Weglinski Jerzy W
Small interfering RNA targeting heme oxygenase-1 (HO-1) reinforces liver apoptosis induced by ischemia-reperfusion injury in mice: HO-1 is necessary for cytoprotection.
Uchida Yoichiro; Freitas Maria Cecilia S; Zhao Danyun; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
The inhibition of neutrophil elastase ameliorates mouse liver damage due to ischemia and reperfusion.

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All Publications

2009: Shen Xiuda; Wang Yue; Gao Feng; Ren Feng; Busuttil Ronald W; Kupiec-Weglinski Jerzy W; Zhai Yuan
CD4 T cells promote tissue inflammation via CD40 signaling without de novo activation in a murine model of liver ischemia/reperfusion injury.
Hepatology (Baltimore, Md.) 2009;50(5):1537-46.
2009: Ke Bibo; Shen Xiu-Da; Gao Feng; Qiao Bo; Ji Haofeng; Busuttil Ronald W; Volk Hans-Dieter; Kupiec-Weglinski Jerzy W
Small interfering RNA targeting heme oxygenase-1 (HO-1) reinforces liver apoptosis induced by ischemia-reperfusion injury in mice: HO-1 is necessary for cytoprotection.
Human gene therapy 2009;20(10):1133-42.
2009: Uchida Yoichiro; Freitas Maria Cecilia S; Zhao Danyun; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
The inhibition of neutrophil elastase ameliorates mouse liver damage due to ischemia and reperfusion.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2009;15(8):939-47.
2008: Farmer Douglas G; Kaldas Fady; Anselmo Dean; Katori Masamichi; Shen Xiu-Da; Lassman Charles; Kaldas Marian; Clozel Martine; Busuttil Ronald W; Kupiec-Weglinski Jerzy
Tezosentan, a novel endothelin receptor antagonist, markedly reduces rat hepatic ischemia and reperfusion injury in three different models.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2008;14(12):1737-44.
2008: Kupiec-Weglinski Jerzy W
Tolerance induction.
Current opinion in organ transplantation 2008;13(4):331-2.
2008: Fondevila Constantino; Shen Xiu-Da; Tsuchihashi Seiichiro; Uchida Yoichiro; Freitas Maria Cecilia; Ke Bibo; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
The membrane attack complex (C5b-9) in liver cold ischemia and reperfusion injury.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2008;14(8):1133-41.
2008: Wu Zheng; Wang Yue; Gao Feng; Shen Xiuda; Zhai Yuan; Kupiec-Weglinski Jerzy W
Critical role of CD4 help in CD154 blockade-resistant memory CD8 T cell activation and allograft rejection in sensitized recipients.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(2):1096-102.
2008: Meng Lingzhong; Wu Zheng; Wang Yue; Lassman Charles; Busuttil Ronald W; Zhai Yuan; Kupiec-Weglinski Jerzy W
Differential impact of CD154 costimulation blockade on alloreactive effector and regulatory T cells in murine renal transplant recipients.
Transplantation 2008;85(9):1332-8.
2008: Vardanian Andrew J; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Molecular mediators of liver ischemia and reperfusion injury: a brief review.
Molecular medicine (Cambridge, Mass.) 2008;14(5-6):337-45.
2008: Zhai Yuan; Qiao Bo; Shen Xiu-Da; Gao Feng; Busuttil Ronald W; Cheng Genhong; Platt Jeffrey L; Volk Hans-Dieter; Kupiec-Weglinski Jerzy W
Evidence for the pivotal role of endogenous toll-like receptor 4 ligands in liver ischemia and reperfusion injury.
Transplantation 2008;85(7):1016-22.
2008: Jindra Peter T; Hsueh Aileen; Hong Longshen; Gjertson David; Shen Xiu-Da; Gao Feng; Dang Julie; Mischel Paul S; Baldwin William M; Fishbein Michael C; Kupiec-Weglinski Jerzy W; Reed Elaine F
Anti-MHC class I antibody activation of proliferation and survival signaling in murine cardiac allografts.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(4):2214-24.
2008: Zhai Yuan; Shen Xiu-Da; Gao Feng; Zhao Alice; Freitas Maria Cecilia; Lassman Charles; Luster Andrew D; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
CXCL10 regulates liver innate immune response against ischemia and reperfusion injury.
Hepatology (Baltimore, Md.) 2008;47(1):207-14.
2008: Zhai Yuan; Qiao Bo; Gao Feng; Shen Xiuda; Vardanian Andrew; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Type I, but not type II, interferon is critical in liver injury induced after ischemia and reperfusion.
Hepatology (Baltimore, Md.) 2008;47(1):199-206.
2007: Shen X-D; Ke B; Zhai Y; Tsuchihashi S-I; Gao F; Duarte S; Coito A; Busuttil R W; Allison A C; Kupiec-Weglinski J W
Diannexin, a novel annexin V homodimer, protects rat liver transplants against cold ischemia-reperfusion injury.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(11):2463-71.
2007: Shen Xiu-Da; Ke Bibo; Zhai Yuan; Gao Feng; Tsuchihashi Sei-Ichiro; Lassman Charles R; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Absence of toll-like receptor 4 (TLR4) signaling in the donor organ reduces ischemia and reperfusion injury in a murine liver transplantation model.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2007;13(10):1435-43.
2007: Zhai Yuan; Wang Yue; Wu Zheng; Kupiec-Weglinski Jerzy W
Defective alloreactive CD8 T cell function and memory response in allograft recipients in the absence of CD4 help.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(7):4529-34.
2007: Semiletova Natalya V; Shen Xiu-Da; Feldman Daniel M; Gao Feng; Mhoyan Ana; Liu Dhai; Busuttil Ronald W; Kupiec-Weglinski Jerzy W; Ghobrial Rafik M
Class I MHC allochimeric presentation of composite immunogenic and self epitopes induces tolerance to genetically diverse rat strains.
Cellular immunology 2007;248(1):48-58.
2007: Tsuchihashi Sei-ichiro; Zhai Yuan; Bo Qiao; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Heme oxygenase-1 mediated cytoprotection against liver ischemia and reperfusion injury: inhibition of type-1 interferon signaling.
Transplantation 2007;83(12):1628-34.
2007: Ke Bibo; Shen Xiu-Da; Tsuchihashi Sei-Ichiro; Gao Feng; Araujo Jesus A; Busuttil Ronald W; Ritter Thomas; Kupiec-Weglinski Jerzy W
Viral interleukin-10 gene transfer prevents liver ischemia-reperfusion injury: Toll-like receptor-4 and heme oxygenase-1 signaling in innate and adaptive immunity.
Human gene therapy 2007;18(4):355-66.
2007: Hoglen Niel C; Anselmo Dean M; Katori Masamichi; Kaldas Marian; Shen Xiu-Da; Valentino Karen L; Lassman Charles; Busuttil Ronald W; Kupiec-Weglinski Jerzy W; Farmer Douglas G
A caspase inhibitor, IDN-6556, ameliorates early hepatic injury in an ex vivo rat model of warm and cold ischemia.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2007;13(3):361-6.
2006: Tsuchihashi Sei-ichiro; Livhits Masha; Zhai Yuan; Busuttil Ronald W; Araujo Jesus A; Kupiec-Weglinski Jerzy W
Basal rather than induced heme oxygenase-1 levels are crucial in the antioxidant cytoprotection.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(7):4749-57.
2006: Barcia Carlos; Thomas Clare E; Curtin James F; King Gwendalyn D; Wawrowsky Kolja; Candolfi Marianela; Xiong Wei-Dong; Liu Chunyan; Kroeger Kurt; Boyer Olivier; Kupiec-Weglinski Jerzy; Klatzmann David; Castro Maria G; Lowenstein Pedro R
In vivo mature immunological synapses forming SMACs mediate clearance of virally infected astrocytes from the brain.
The Journal of experimental medicine 2006;203(9):2095-107.
2006: Tsuchihashi S; Kaldas F; Chida N; Sudo Y; Tamura K; Zhai Y; Qiao B; Busuttil R W; Kupiec-Weglinski J W
FK330, a novel inducible nitric oxide synthase inhibitor, prevents ischemia and reperfusion injury in rat liver transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2006;6(9):2013-22.
2006: Zhai Yuan; Shen Xiu-da; Hancock Wayne W; Gao Feng; Qiao Bo; Lassman Charles; Belperio John A; Strieter Robert M; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
CXCR3+CD4+ T cells mediate innate immune function in the pathophysiology of liver ischemia/reperfusion injury.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(10):6313-22.
2006: Zhai Yuan; Meng Lingzhong; Gao Feng; Wang Yue; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
CD4+ T regulatory cell induction and function in transplant recipients after CD154 blockade is TLR4 independent.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(10):5988-94.
2006: Bailly-Maitre Béatrice; Fondevila Constantino; Kaldas Fady; Droin Nathalie; Luciano Fréderic; Ricci Jean-Ehrland; Croxton Rhonda; Krajewska Maryla; Zapata Juan M; Kupiec-Weglinski Jerzy W; Farmer Douglas; Reed John C
Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(8):2809-14.
2006: Tsuchihashi Sei-ichiro; Ke Bibo; Kaldas Fady; Flynn Evelyn; Busuttil Ronald W; Briscoe David M; Kupiec-Weglinski Jerzy W
Vascular endothelial growth factor antagonist modulates leukocyte trafficking and protects mouse livers against ischemia/reperfusion injury.
The American journal of pathology 2006;168(2):695-705.
2006: Tsuchihashi Sei-ichiro; Fondevila Constantino; Shaw Gray D; Lorenz Meike; Marquette Kimberly; Benard Susan; Shen Xiu-Da; Ke Bibo; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Molecular characterization of rat leukocyte P-selectin glycoprotein ligand-1 and effect of its blockade: protection from ischemia-reperfusion injury in liver transplantation.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(1):616-24.
2006: Ke Bibo; Lipshutz Gerald S; Kupiec-Weglinski Jerzy W
Gene therapy in liver ischemia and reperfusion injury.
Current pharmaceutical design 2006;12(23):2969-75.
2005: Semiletova Natalya V; Shen Xiu-Da; Baibakov Boris; Feldman Daniel M; Mukherjee Kaushik; Frank Jonathan M; Stepkowski Stainslaw M; Busuttil Ronald W; Kupiec-Weglinski Jerzy W; Ghobrial Rafik M
Inhibition of chronic rejection by antibody induced vascular accommodation in fully allogeneic heart allografts.
Transplantation 2005;80(11):1535-40.
2005: Shen Xiu-Da; Gao Feng; Ke Bibo; Zhai Yuan; Lassman Charles R; Tsuchihashi Sei-Ichiro; Farmer Douglas G; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Inflammatory responses in a new mouse model of prolonged hepatic cold ischemia followed by arterialized orthotopic liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2005;11(10):1273-81.
2005: Farmer Douglas G; Anselmo Dean; Da Shen Xiu; Ke Bibo; Carmody Ian C; Gao Feng; Lassman Charles; McDiarmid Sue V; Shaw Grey; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Disruption of P-selectin signaling modulates cell trafficking and results in improved outcomes after mouse warm intestinal ischemia and reperfusion injury.
Transplantation 2005;80(6):828-35.
2005: Ali Sumia; King Gwendalyn D; Curtin James F; Candolfi Marianela; Xiong Weidong; Liu Chunyan; Puntel Mariana; Cheng Queng; Prieto Jesus; Ribas Antoni; Kupiec-Weglinski Jerzy; van Rooijen Nico; Lassmann Hans; Lowenstein Pedro R; Castro Maria G
Combined immunostimulation and conditional cytotoxic gene therapy provide long-term survival in a large glioma model.
Cancer research 2005;65(16):7194-204.
2005: Shen Xiu-Da; Ke Bibo; Zhai Yuan; Gao Feng; Busuttil Ronald W; Cheng Genhong; Kupiec-Weglinski Jerzy W
Toll-like receptor and heme oxygenase-1 signaling in hepatic ischemia/reperfusion injury.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(8):1793-800.
2005: Liu D; Shen X-D; Fang Z; Gao F; Semiletova N; Cao M-J; Busuttil R W; Kupiec-Weglinski J W; Ghobrial R M
Identification of early tolerance regulator genes induced by allochimeric therapy using microarray-based genomewide scan.
Transplantation proceedings 2005;37(4):1942-3.
2005: Semiletova N V; Shen X-D; Feldman D M; Busuttil R W; Kupiec-Weglinski J W; Ghobrial R M
Donor MHC class I peptides in conjunction with self-epitopes induce donor-specific tolerance in a dose-dependent manner but unable to abrogate chronic rejection.
Transplantation proceedings 2005;37(4):1937-9.
2005: Tsuchihashi S; Zhai Y; Fondevila C; Busuttil R W; Kupiec-Weglinski J W
HO-1 upregulation suppresses type 1 IFN pathway in hepatic ischemia/reperfusion injury.
Transplantation proceedings 2005;37(4):1677-8.
2005: Kupiec-Weglinski J W; Busuttil R W
Ischemia and reperfusion injury in liver transplantation.
Transplantation proceedings 2005;37(4):1653-6.
2005: Ke Bibo; Shen Xiu-Da; Gao Feng; Tsuchihashi Seiichiro; Farmer Douglas G; Briscoe David; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
The CD154-CD40 T-cell co-stimulation pathway in liver ischemia and reperfusion inflammatory responses.
Transplantation 2005;79(9):1078-83.
2005: Semiletova N V; Shen X D; Slomowitz S J; Baibakov B; Feldman D M; Busuttil R W; Kupiec-Weglinski J W; Ghobrial R M
Allochimeric therapy induces unique regulatory T cells that mitigate chronic rejection.
Transplantation proceedings 2005;37(1):35-6.
2005: Farmer Douglas G; Shen Xiu-Da; Amersi Farin; Anselmo Dean; Ma Jeffrey P; Ke Bibo; Gao Feng; Dry Sarah; Fernandez Susan; Shaw Gray D; McDiarmid Sue V; Busuttil Ronald W; Kupiec-Weglinski Jerzy
CD62 blockade with P-Selectin glycoprotein ligand-immunoglobulin fusion protein reduces ischemia-reperfusion injury after rat intestinal transplantation.
Transplantation 2005;79(1):44-51.
2004: Zhai Yuan; Shen Xiu-da; O'Connell Ryan; Gao Feng; Lassman Charles; Busuttil Ronald W; Cheng Genhong; Kupiec-Weglinski Jerzy W
Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(12):7115-9.
2004: Fondevila Constantino; Shen Xiu-Da; Tsuchiyashi Seiichiro; Yamashita Kenichiro; Csizmadia Eva; Lassman Charles; Busuttil Ronald W; Kupiec-Weglinski Jerzy W; Bach Fritz H
Biliverdin therapy protects rat livers from ischemia and reperfusion injury.
Hepatology (Baltimore, Md.) 2004;40(6):1333-41.
2004: Ke Bibo; Shen Xiu-Da; Gao Feng; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Interleukin 13 gene transfer in liver ischemia and reperfusion injury: role of Stat6 and TLR4 pathways in cytoprotection.
Human gene therapy 2004;15(7):691-8.
2004: Takemoto Steven K; Zeevi Adriana; Feng Sandy; Colvin Robert B; Jordan Stanley; Kobashigawa Jon; Kupiec-Weglinski Jerzy; Matas Arthur; Montgomery Robert A; Nickerson Peter; Platt Jeffrey L; Rabb Hamid; Thistlethwaite Richard; Tyan Dolly; Delmonico Francis L
National conference to assess antibody-mediated rejection in solid organ transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2004;4(7):1033-41.
2004: Carmody I C; Meng L; Shen X D; Anselmo D; Gao F; Ke B; Ma J P; Kupiec-Weglinski J W; McDiarmid S V; Busuttil R W; Shaw G; Farmer D G
P-selectin knockout mice have improved outcomes with both warm ischemia and small bowel transplantation.
Transplantation proceedings 2004;36(2):263-4.
2004: Ke Bibo; Shen Xiu-Da; Gao Feng; Busuttil Ronald W; Löwenstein Pedro R; Castro Maria G; Kupiec-Weglinski Jerzy W
Gene therapy for liver transplantation using adenoviral vectors: CD40-CD154 blockade by gene transfer of CD40Ig protects rat livers from cold ischemia and reperfusion injury.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;9(1):38-45.
2004: Tsuchihashi Sei-ichiro; Fondevila Constantino; Kupiec-Weglinski Jerzy W
Heme oxygenase system in ischemia and reperfusion injury.
Annals of transplantation : quarterly of the Polish Transplantation Society 2004;9(1):84-7.
2003: Berberat P O; Katori M; Kaczmarek E; Anselmo D; Lassman C; Ke B; Shen X; Busuttil R W; Yamashita Kenichiro; Csizmadia Eva; Tyagi Shivraj; Otterbein Leo E; Brouard S; Tobiasch E; Bach F H; Kupiec-Weglinski J W; Soares M P
Heavy chain ferritin acts as an antiapoptotic gene that protects livers from ischemia reperfusion injury.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(12):1724-6.
2003: Ke Bibo; Shen Xiu-Da; Lassman Charles R; Gao Feng; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Cytoprotective and antiapoptotic effects of IL-13 in hepatic cold ischemia/reperfusion injury are heme oxygenase-1 dependent.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2003;3(9):1076-82.
2003: Fondevila C; Katori M; Lassman C; Carmody I; Busuttil R W; Bach F H; Kupiec-Weglinski J W
Biliverdin protects rat livers from ischemia/reperfusion injury.
Transplantation proceedings 2003;35(5):1798-9.
2003: Araujo Jesus A; Meng Lingzhong; Tward Aaron D; Hancock Wayne W; Zhai Yuan; Lee Annie; Ishikawa Kazunobu; Iyer Suhasini; Buelow Roland; Busuttil Ronald W; Shih Diana M; Lusis Aldons J; Kupiec-Weglinski Jerzy W
Systemic rather than local heme oxygenase-1 overexpression improves cardiac allograft outcomes in a new transgenic mouse.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(3):1572-80.
2003: Zhai Yuan; Kupiec-Weglinski Jerzy W
Regulatory T cells in kidney transplant recipients: active players but to what extent?
Journal of the American Society of Nephrology : JASN 2003;14(6):1706-8.
2003: Kupiec-Weglinski J W
Interactions between pharmaceutical industry and academia revisited: the University of California at Los Angeles case.
Transplantation proceedings 2003;35(3):1238-9.
2003: Ke Bibo; Shen Xiu-Da; Lassman Charles R; Gao Feng; Katori Masamichi; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Interleukin-13 gene transfer protects rat livers from antigen-independent injury induced by ischemia and reperfusion.
Transplantation 2003;75(8):1118-23.
2003: Fondevila Constantino; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Hepatic ischemia/reperfusion injury--a fresh look.
Experimental and molecular pathology 2003;74(2):86-93.
2003: Amersi Farin; Shen Xiu-Da; Moore Carolina; Melinek Judy; Busuttil Ronald W; Kupiec-Weglinski Jerzy W; Coito Ana J
Fibronectin-alpha 4 beta 1 integrin-mediated blockade protects genetically fat Zucker rat livers from ischemia/reperfusion injury.
The American journal of pathology 2003;162(4):1229-39.
2003: Zhai Yuan; Meng Lingzhong; Busuttil Ronald W; Sayegh Mohamed H; Kupiec-Weglinski Jerzy W
Activation of alloreactive CD8+ T cells operates via CD4-dependent and CD4-independent mechanisms and is CD154 blockade sensitive.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(6):3024-8.
2003: Blydt-Hansen Tom D; Katori Masamichi; Lassman Charles; Ke Bibo; Coito Ana J; Iyer Suhasani; Buelow Roland; Ettenger Robert; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Gene transfer-induced local heme oxygenase-1 overexpression protects rat kidney transplants from ischemia/reperfusion injury.
Journal of the American Society of Nephrology : JASN 2003;14(3):745-54.
2003: Semiltova Natalya; Shen Xiu-Da; Fishbein Michael C; Gao Feng; Slomowitz Samuel J; Jiao Qingsheng; Mukherjee Kaushik; Busuttil Ronald W; Kupiec-Weglinski Jerzy W; Ghobrial Rafik M
Posttransplant administration of allochimeric major histocompatibility complex class-I-molecules induces true transplantation tolerance.
Transplantation 2003;75(4):550-3.
2003: Zhai Yuan; Kupiec-Weglinski Jerzy W
T-cell receptor beta-chain usage in directly activated alloreactive CD4+ T cells: unrestricted Vbeta gene usage with CDR3 size limitations.
Transplantation 2003;75(4):514-21.
2003: Shen Xiu-Da; Ke Bibo; Zhai Yuan; Gao Feng; Anselmo Dean; Lassman Charles R; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Stat4 and Stat6 signaling in hepatic ischemia/reperfusion injury in mice: HO-1 dependence of Stat4 disruption-mediated cytoprotection.
Hepatology (Baltimore, Md.) 2003;37(2):296-303.
2002: Ke Bibo; Shen Xiu-Da; Zhai Yuan; Gao Feng; Busuttil Ronald W; Volk Hans-Dieter; Kupiec-Weglinski Jerzy W
Heme oxygenase 1 mediates the immunomodulatory and antiapoptotic effects of interleukin 13 gene therapy in vivo and in vitro.
Human gene therapy 2002;13(15):1845-57.
2002: Katori Masamichi; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Heme oxygenase-1 system in organ transplantation.
Transplantation 2002;74(7):905-12.
2002: Anselmo Dean M; Amersi Farin F; Shen Xiu-Da; Gao Feng; Katori Masamichi; Lassman Charles; Ke Bibo; Coito Ana J; Ma Jeffrey; Brinkmann Volker; Busuttil Ronald W; Kupiec-Weglinski Jerzy W; Farmer Douglas G
FTY720 pretreatment reduces warm hepatic ischemia reperfusion injury through inhibition of T-lymphocyte infiltration.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2002;2(9):843-9.
2002: Zhai Yuan; Meng Lingzhong; Gao Feng; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Allograft rejection by primed/memory CD8+ T cells is CD154 blockade resistant: therapeutic implications for sensitized transplant recipients.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(8):4667-73.
2002: Sawitzki Birgit; Amersi Farin; Ritter Thomas; Fisser Marion; Shen Xiu-Da; Ke Bibo; Busuttil Ronald; Volk Hans-Dieter; Kupiec-Weglinski Jerzy W
Upregulation of Bag-1 by ex vivo gene transfer protects rat livers from ischemia/reperfusion injury.
Human gene therapy 2002;13(12):1495-504.
2002: Amersi Farin; Farmer Douglas G; Shaw Gray D; Kato Hirohisa; Coito Ana J; Kaldas Fady; Zhao Delai; Lassman Charles R; Melinek Judy; Ma Jeffrey; Volk Hans-Dieter; Kupiec-Weglinski Jerzy W; Busuttil Ronald W
P-selectin glycoprotein ligand-1 (rPSGL-Ig)-mediated blockade of CD62 selectin molecules protects rat steatotic liver grafts from ischemia/reperfusion injury.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2002;2(7):600-8.
2002: Shen Xiu-Da; Ke Bibo; Zhai Yuan; Amersi Farin; Gao Feng; Anselmo Dean M; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
CD154-CD40 T-cell costimulation pathway is required in the mechanism of hepatic ischemia/reperfusion injury, and its blockade facilitates and depends on heme oxygenase-1 mediated cytoprotection.
Transplantation 2002;74(3):315-9.
2002: Anselmo D; Amersi F F; Shen X-D; Gao F; Katori M; Ke B; Lassman C; Coito A J; Brinkmann V; Busuttil R W; Kupiec-Weglinski J W; Farmer D G
FTY720: a novel approach to the treatment of hepatic ischemia-reperfusion injury.
Transplantation proceedings 2002;34(5):1467-8.
2002: Ke B; Shen X-D; Buelow R; Melinek J; Amersi F; Gao F; Ritter T; Volk H D; Busuttil R W; Kupiec-Weglinski J W
Heme oxygenase-1 gene transfer prevents CD95/FasL-mediated apoptosis and improves liver allograft survival via carbon monoxide signaling pathway.
Transplantation proceedings 2002;34(5):1465-6.
2002: Coito Ana J; Shaw G D; Meng L; Moore C; Ma J; Busuttil R W; Kupiec-Weglinski J W
CD62-PSGL-1 interactions regulate cytokine chemokine and apoptotic networks in cardiac allograft recipients.
Transplantation proceedings 2002;34(5):1463-4.
2002: Semiletova N; Shen X D; Gao F; Slomowitz S J; Jiao Q; Busuttil R W; Kupiec-Weglinski J W; Ghobrial R M
Regulatory T cells induced by allochimeric major histocompatability class I therapy inhibit allograft apoptosis.
Transplantation proceedings 2002;34(5):1402.
2002: Zhai Yuan; Shen Xiu-Da; Gao Feng; Coito Ana J; Wasowska Barbara A; Salama Alan; Schmitt Isabela; Busuttil Ronald W; Sayegh Mohamed H; Kupiec-Weglinski Jerzy W
The CD154-CD40 T cell costimulation pathway is required for host sensitization of CD8(+) T cells by skin grafts via direct antigen presentation.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(3):1270-6.
2002: Coito Ana J; Buelow Roland; Shen Xiu-Da; Amersi Farin; Moore Carolina; Volk Hans-Dieter; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Heme oxygenase-1 gene transfer inhibits inducible nitric oxide synthase expression and protects genetically fat Zucker rat livers from ischemia-reperfusion injury.
Transplantation 2002;74(1):96-102.
2002: Ke Bibo; Buelow Roland; Shen Xiu-Da; Melinek Judy; Amersi Farin; Gao Feng; Ritter Thomas; Volk Hans-Dieter; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Heme oxygenase 1 gene transfer prevents CD95/Fas ligand-mediated apoptosis and improves liver allograft survival via carbon monoxide signaling pathway.
Human gene therapy 2002;13(10):1189-99.
2002: Amersi Farin; Nelson Sally K; Shen Xiu Da; Kato Hirohisa; Melinek Judy; Kupiec-Weglinski Jerzy W; Horwitz Lawrence D; Busuttil Ronald W; Horwitz Marcus A
Bucillamine, a thiol antioxidant, prevents transplantation-associated reperfusion injury.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(13):8915-20.
2002: Sawitzki Birgit; Lehmann Manfred; Vogt Katrin; Seifert Martina; Risch Kirsten; Brock Josef; Kupiec-Weglinski Jerzy W; Volk Hans-Dieter
Bag-1 up-regulation in anti-CD4 mAb-treated allo-activated T cell confers resistance to activation-induced cell death (AICD).
Transplant immunology 2002;9(2-4):83-91.
2002: Katori Masamichi; Anselmo Dean M; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
A novel strategy against ischemia and reperfusion injury: cytoprotection with heme oxygenase system.
Transplant immunology 2002;9(2-4):227-33.
2002: Farmer D G; Amersi F; Shen X D; Gao F; Anselmo D; Ma J; Dry S; McDiarmid S V; Shaw G; Busuttil R W; Kupiec-Weglinski J
Improved survival through the reduction of ischemia-reperfusion injury after rat intestinal transplantation using selective P-selectin blockade with P-selectin glycoprotein ligand-Ig.
Transplantation proceedings 2002;34(3):985.
2002: Hancock Wayne W; Gao Wei; Shemmeri Nida; Shen Xiu-Da; Gao Feng; Busuttil Ronald W; Zhai Yuan; Kupiec-Weglinski Jerzy W
Immunopathogenesis of accelerated allograft rejection in sensitized recipients: humoral and nonhumoral mechanisms.
Transplantation 2002;73(9):1392-7.
2002: Amersi Farin; Shen Xiu-Da; Anselmo Dean; Melinek Judy; Iyer Suhasani; Southard Daniel J; Katori Masamichi; Volk Hans-Dieter; Busuttil Ronald W; Buelow Roland; Kupiec-Weglinski Jerzy W
Ex vivo exposure to carbon monoxide prevents hepatic ischemia/reperfusion injury through p38 MAP kinase pathway.
Hepatology (Baltimore, Md.) 2002;35(4):815-23.
2002: Sawitzki Birgit; Lehmann Manfred; Vogt Katrin; Risch Kirsten; Brock Josef; Kupiec-Weglinski Jerzy W; Volk Hans-Dieter
Bag-1 up-regulation in anti-CD4 mAb treated allo-activated T cells confers resistance to apoptosis.
European journal of immunology 2002;32(3):800-9.
2002: Katori Masamichi; Buelow Roland; Ke Bibo; Ma Jeff; Coito Ana J; Iyer Suhasini; Southard Daniel; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Heme oxygenase-1 overexpression protects rat hearts from cold ischemia/reperfusion injury via an antiapoptotic pathway.
Transplantation 2002;73(2):287-92.
2002: Coito Ana J; Shaw Gray D; Li Jiye; Ke Bibo; Ma Jeffrey; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Selectin-mediated interactions regulate cytokine networks and macrophage heme oxygenase-1 induction in cardiac allograft recipients.
Laboratory investigation; a journal of technical methods and pathology 2002;82(1):61-70.
2001: Singer J S; Mhoyan A; Fishbein M C; Shen X D; Gao F; Zhao D; Coito A J; Reemtsen B L; Amersi F; Busuttil R W; Kupiec-Weglinski J W; Ghobrial R M
Allochimeric class I MHC molecules prevent chronic rejection and attenuate alloantibody responses.
Transplantation 2001;72(8):1408-16.
2001: Kato H; Amersi F; Buelow R; Melinek J; Coito A J; Ke B; Busuttil R W; Kupiec-Weglinski J W
Heme oxygenase-1 overexpression protects rat livers from ischemia/reperfusion injury with extended cold preservation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2001;1(2):121-8.
2001: Zhai Y; Li J; Hammer M; Busuttil R W; Volk H D; Kupiec-Weglinski J W
Evidence of T cell clonality in the infectious tolerance pathway: implications toward identification of regulatory T cells.
Transplantation 2001;71(12):1701-8.
2001: Sawitzki B; Lehmann M; Ritter T; Graser E; Kupiec-Weglinski J W; Volk H D
Regulatory tolerance-mediating T cells in transplantation tolerance.
Transplantation proceedings 2001;33(3):2092-3.
2001: Ke B; Shen X D; Melinek J; Gao F; Ritter T; Volk H D; Busuttil R W; Kupiec-Weglinski J W
Heme oxygenase-1 gene therapy: a novel immunomodulatory approach in liver allograft recipients?
Transplantation proceedings 2001;33(1-2):581-2.
2001: Ghobrial R; Amersi F; Stecker K; Kato H; Melinek J; Singer J; Mhoyan A; Busuttil R W; Kupiec-Weglinski J W; Stepkowski S M
Amelioration of hepatic ischemia/reperfusion injury with intercellular adhesion molecule-1 antisense oligodeoxynucleotides.
Transplantation proceedings 2001;33(1-2):538.
2001: Coito A J; Kato H; Azimi R; Kupiec-Weglinski J W
Chronic allograft rejection versus tolerance: a critical role for EIIIA(+) fibronectin.
Transplantation proceedings 2001;33(1-2):526-7.
2001: Kupiec-Weglinski J W; Shen X D; Gao F; Zhai Y; Coito A J; Sayegh M H
CD40 ligand-CD40 T cell costimulation pathway is required for host sensitization in the immune cascade leading to accelerated allograft rejection.
Transplantation proceedings 2001;33(1-2):304-5.
2001: Amersi F; Dulkanchainun T; Nelson S K; Farmer D G; Kato H; Zaky J; Melinek J; Shaw G D; Kupiec-Weglinski J W; Horwitz L D; Horwitz M A; Busuttil R W
A novel iron chelator in combination with a P-selectin antagonist prevents ischemia/reperfusion injury in a rat liver model.
Transplantation 2001;71(1):112-8.
2001: Hammer M H; Zhai Y; Katori M; Ritter T; Volk H D; Coito A J; Kupiec-Weglinski J W
Homing of in vitro-generated donor antigen-reactive CD4+ T lymphocytes to renal allografts is alpha 4 beta 1 but not alpha L beta 2 integrin dependent.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(1):596-601.
2000: Coito A J; Onodera K; Kato H; Busuttil R W; Kupiec-Weglinski J W
Fibronectin-mononuclear cell interactions regulate type 1 helper T cell cytokine network in tolerant transplant recipients.
The American journal of pathology 2000;157(4):1207-18.
2000: Coito A J; Kupiec-Weglinski J W
Extracellular matrix proteins in organ transplantation.
Transplantation 2000;69(12):2465-73.
2000: Ke B; Coito A J; Kato H; Zhai Y; Wang T; Sawitzki B; Seu P; Busuttil R W; Kupiec-Weglinski J W
Fas ligand gene transfer prolongs rat renal allograft survival and down-regulates anti-apoptotic Bag-1 in parallel with enhanced Th2-type cytokine expression.
Transplantation 2000;69(8):1690-4.
2000: Kato H; Ritter T; Ke B; Murakami M; Kusano M; Busuttil R W; Kupiec-Weglinski J W
Adenovirus-mediated gene transfer of IL-4 prolongs rat renal allograft survival and inhibits the p21(ras)-activation pathway.
Transplantation proceedings 2000;32(2):245-6.
2000: Kupiec-Weglinski J W
CD25-targeted therapy revisited.
Transplantation 2000;69(3):328-30.
2000: Coito A J; de Sousa M; Kupiec-Weglinski J W
Fibronectin in immune responses in organ transplant recipients.
Developmental immunology 2000;7(2-4):239-48.
1999: Amersi F; Buelow R; Kato H; Ke B; Coito A J; Shen X D; Zhao D; Zaky J; Melinek J; Lassman C R; Kolls J K; Alam J; Ritter T; Volk H D; Farmer D G; Ghobrial R M; Busuttil R W; Kupiec-Weglinski J W
Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury.
The Journal of clinical investigation 1999;104(11):1631-9.
1999: Zhai Y; Kupiec-Weglinski J W
What is the role of regulatory T cells in transplantation tolerance?
Current opinion in immunology 1999;11(5):497-503.
1999: Reemtsen B L; Kato H; Wang T S; Busuttil R W; Kupiec-Weglinski J W; Goss J A
Intrathymic immunomodulation and the "infectious" tolerance pathway in allograft recipients.
The Journal of surgical research 1999;84(1):1-7.
1999: Onodera K; Chandraker A; Kato H; Volk H D; Sayegh M H; Kupiec-Weglinski J W
Distinct tolerance pathways in sensitized rat recipients after blockade of activation signal 1 and signal 2.
Transplantation proceedings 1999;31(1-2):876-7.
1999: Maggard M A; Johnson C; Wang T; Terasaki P; Kupiec-Weglinski J W; Busuttil R W; Imagawa D K
Inhibition of transplant vasculopathy is associated with attenuated host allo-antibody response.
Transplantation proceedings 1999;31(1-2):728-9.
1999: Zhai Y; Ghobrial R M; Busuttil R W; Kupiec-Weglinski J W
Th1 and Th2 cytokines in organ transplantation: paradigm lost?
Critical reviews in immunology 1999;19(2):155-72.
1998: Dulkanchainun T S; Goss J A; Imagawa D K; Shaw G D; Anselmo D M; Kaldas F; Wang T; Zhao D; Busuttil A A; Kato H; Murray N G; Kupiec-Weglinski J W; Busuttil R W
Reduction of hepatic ischemia/reperfusion injury by a soluble P-selectin glycoprotein ligand-1.
Annals of surgery 1998;227(6):832-40.
1998: Kupiec-Weglinski J W; Onodera K; Volk H D
The "infectious" tolerance pathway in organ allograft recipients.
Transplantation proceedings 1998;30(4):1595-7.
1997: Lehmann M; Graser E; Risch K; Hancock W W; Müller A; Kuttler B; Hahn H J; Kupiec-Weglinski J W; Brock J; Volk H D
Anti-CD4 monoclonal antibody-induced allograft tolerance in rats despite persistence of donor-reactive T cells.
Transplantation 1997;64(8):1181-7.
1997: Graser E; Risch K; Linsley P S; Hancock W W; Müller A; Brock J; Reinke P; Kupiec-Weglinski J W; Volk H D; Lehmann M
Synergism of CTLA4-IG and anti-CD4 monoclonal antibody treatment in a rat kidney transplant model.
Transplantation proceedings 1997;29(1-2):1307-9.

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