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Yoshihisa Kurachi

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Fumiaki Nin; Toshihiro Suzuki; Hiroshi Hibino; Yasuo Hisa; Shingo Murakami; Yoshihisa Kurachi
Computational model of a circulation current that controls electrochemical properties in the mammalian cochlea.
Yuko Yamakawa; Yuko Ohno; Kazuharu Furutani; Atsushi Inanobe; Yoshihisa Kurachi
Pharmacophore modeling for hERG channel facilitation.
Kazuharu Furutani; Atsushi Inanobe; Miki Iwata; Yuko Ohno; Yuko Yamakawa; Yoshihisa Kurachi
A mechanism underlying compound-induced voltage shift in the current activation of hERG by antiarrhythmic agents.

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2012: Fumiaki Nin; Toshihiro Suzuki; Hiroshi Hibino; Yasuo Hisa; Shingo Murakami; Yoshihisa Kurachi
Computational model of a circulation current that controls electrochemical properties in the mammalian cochlea.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(23):9191-6.
2012: Yuko Yamakawa; Yuko Ohno; Kazuharu Furutani; Atsushi Inanobe; Yoshihisa Kurachi
Pharmacophore modeling for hERG channel facilitation.
Biochemical and biophysical research communications 2012;418(1):161-6.
2011: Kazuharu Furutani; Atsushi Inanobe; Miki Iwata; Yuko Ohno; Yuko Yamakawa; Yoshihisa Kurachi
A mechanism underlying compound-induced voltage shift in the current activation of hERG by antiarrhythmic agents.
Biochemical and biophysical research communications 2011;415(1):141-6.
2011: Atsushi Inanobe; Takanori Matsuura; Atsushi Nakagawa; Yoshihisa Kurachi
Inverse agonist-like action of cadmium on G-protein-gated inward-rectifier K(+) channels.
Biochemical and biophysical research communications 2011;407(2):366-71.
2011: Kunichika Tsumoto; Takashi Ashihara; Ryo Haraguchi; Kazuo Nakazawa; Yoshihisa Kurachi
Roles of subcellular Na+ channel distributions in the mechanism of cardiac conduction.
Biophysical journal 2011;100(3):554-63.
2010: Masashi Ikushima; Masaru Ishii; Mitsuru Ohishi; Koichi Yamamoto; Toshio Ogihara; Hiromi Rakugi; Yoshihisa Kurachi
ANG II inhibits insulin-mediated production of PI 3,4,5-trisphosphates via a Ca2+-dependent but PKC-independent pathway in the cardiomyocytes.
American journal of physiology. Heart and circulatory physiology 2010;299(3):H680-9.
2010: Shingo Murakami; Shingo Suzuki; Masaru Ishii; Atsushi Inanobe; Yoshihisa Kurachi
Cellular modelling: experiments and simulation to develop a physiological model of G-protein control of muscarinic K+ channels in mammalian atrial cells.
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 2010;368(1921):2983-3000.
2010: Rachid Ait-Haddou; Yoshihisa Kurachi; taishin nomura
On calcium-buffer dynamics within the excess buffer regime.
Journal of theoretical biology 2010;264(1):55-65.
2010: Hiroshi Hibino; Fumiaki Nin; Chizuru Tsuzuki; Yoshihisa Kurachi
How is the highly positive endocochlear potential formed? The specific architecture of the stria vascularis and the roles of the ion-transport apparatus.
Pflügers Archiv : European journal of physiology 2010;459(4):521-33.
2010: Hiroshi Hibino; Atsushi Inanobe; Kazuharu Furutani; Shingo Murakami; Ian Findlay; Yoshihisa Kurachi
Inwardly rectifying potassium channels: their structure, function, and physiological roles.
Physiological reviews 2010;90(1):291-366.
2009: Kazuharu Furutani; Yukihiro Ohno; Atsushi Inanobe; Hiroshi Hibino; Yoshihisa Kurachi
Mutational and in silico analyses for antidepressant block of astroglial inward-rectifier Kir4.1 channel.
Molecular pharmacology 2009;75(6):1287-95.
2009: Yasuyuki Suzuki; Yoshiyuki Asai; Hideki Oka; Eric Heien; Takahito Urai; Tatsuhide Okamoto; Yosuke Yumikura; Keisuke Tominaga; Yoshiyuki Kido; Masao Nakanishi; Keisuke Hagihara; Yoshihisa Kurachi; taishin nomura
A platform for in silico modeling of physiological systems III.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2009;2009():2803-6.
2008: Shingo Suzuki; Shingo Murakami; Kenji Tsujimae; Ian Findlay; Yoshihisa Kurachi
In silico risk assessment for drug-induction of cardiac arrhythmia.
Progress in biophysics and molecular biology 2008;98(1):52-60.
2008: Yukinori Hasegawa; Yasukazu Kanai; Shinji Hasegawa; Takashi Okamoto; Tamiko Matsui; Eku Shimosegawa; Yoshihisa Kurachi; Jun Hatazawa
Evaluation of brain and whole-body pharmacokinetics of 11C-labeled diphenylhydantoin in rats by means of planar positron imaging system.
Annals of nuclear medicine 2008;22(4):301-7.
2008: Fumiaki Nin; Hiroshi Hibino; Katsumi Doi; Toshihiro Suzuki; Yasuo Hisa; Yoshihisa Kurachi
The endocochlear potential depends on two K+ diffusion potentials and an electrical barrier in the stria vascularis of the inner ear.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(5):1751-6.
2008: Kenji Tsujimae; Shingo Murakami; Yoshihisa Kurachi
In silico study on the effects of IKur block kinetics on prolongation of human action potential after atrial fibrillation-induced electrical remodeling.
American journal of physiology. Heart and circulatory physiology 2008;294(2):H793-800.
2008: Yasuyuki Suzuki; Yoshiyuki Asai; Toshihiro Kawazu; Masao Nakanishi; Yoshiki Taniguchi; Eric Heien; Kenichi Hagihara; Yoshihisa Kurachi; taishin nomura
A platform for in silico modeling of physiological systems II. CellML compatibility and other extended capabilities.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2008;2008():573-6.
2007: Hiroshi Hibino; Yoshihisa Kurachi
Distinct detergent-resistant membrane microdomains (lipid rafts) respectively harvest K(+) and water transport systems in brain astroglia.
The European journal of neuroscience 2007;26(9):2539-55.
2007: Yukihiro Ohno; Hiroshi Hibino; Christoph Lossin; Atsushi Inanobe; Yoshihisa Kurachi
Inhibition of astroglial Kir4.1 channels by selective serotonin reuptake inhibitors.
Brain research 2007;1178():44-51.
2007: Kenji Tsujimae; Shingo Suzuki; Shingo Murakami; Yoshihisa Kurachi
Frequency-dependent effects of various IKr blockers on cardiac action potential duration in a human atrial model.
American journal of physiology. Heart and circulatory physiology 2007;293(1):H660-9.
2007: Yukio Hosaka; Miki Iwata; Narutoshi Kamiya; Mitsuhiko Yamada; Kengo Kinoshita; Yoshifumi Fukunishi; Kenji Tsujimae; Hiroshi Hibino; Yoshifusa Aizawa; Atsushi Inanobe; Haruki Nakamura; Yoshihisa Kurachi
Mutational analysis of block and facilitation of HERG current by a class III anti-arrhythmic agent, nifekalant.
Channels (Austin, Tex.) 2007;1(3):198-208.
2007: Suwen Su; Yukihiro Ohno; Christoph Lossin; Hiroshi Hibino; Atsushi Inanobe; Yoshihisa Kurachi
Inhibition of astroglial inwardly rectifying Kir4.1 channels by a tricyclic antidepressant, nortriptyline.
The Journal of pharmacology and experimental therapeutics 2007;320(2):573-80.
2007: Atsushi Inanobe; Takanori Matsuura; Atsushi Nakagawa; Yoshihisa Kurachi
Structural diversity in the cytoplasmic region of G protein-gated inward rectifier K+ channels.
Channels (Austin, Tex.) 2007;1(1):39-45.
2006: Toshiaki Shibata; Hiroshi Hibino; Katsumi Doi; Toshihiro Suzuki; Yasuo Hisa; Yoshihisa Kurachi
Gastric type H+,K+-ATPase in the cochlear lateral wall is critically involved in formation of the endocochlear potential.
American journal of physiology. Cell physiology 2006;291(5):C1038-48.
2006: Hiroshi Hibino; Yoshihisa Kurachi
Molecular and physiological bases of the K+ circulation in the mammalian inner ear.
Physiology (Bethesda, Md.) 2006;21():336-45.
2006: Jun-ichi Kikuta; Masaru Ishii; Kentaro Kishimoto; Yoshihisa Kurachi
Carvedilol blocks cardiac KATP and KG but not IK1 channels by acting at the bundle-crossing regions.
European journal of pharmacology 2006;529(1-3):47-54.
2005: Masaru Ishii; Masashi Ikushima; Yoshihisa Kurachi
In vivo interaction between RGS4 and calmodulin visualized with FRET techniques: possible involvement of lipid raft.
Biochemical and biophysical research communications 2005;338(2):839-46.
2005: Kenjiro Sawada; Ken-ichirou Morishige; Kae Hashimoto; Keiichi Tasaka; Hirohisa Kurachi; Yuji Murata; Yoshihisa Kurachi
Gestational change of K+ channel opener effect is correlated with the expression of uterine KATP channel subunits.
European journal of obstetrics, gynecology, and reproductive biology 2005;122(1):49-56.
2005: Mitsuhiko Yamada; Yoshihisa Kurachi
A functional role of the C-terminal 42 amino acids of SUR2A and SUR2B in the physiology and pharmacology of cardiovascular ATP-sensitive K(+) channels.
Journal of molecular and cellular cardiology 2005;39(1):1-6.
2005: Masaru Ishii; Satoru Fujita; Mitsuhiko Yamada; Yukio Hosaka; Yoshihisa Kurachi
Phosphatidylinositol 3,4,5-trisphosphate and Ca2+/calmodulin competitively bind to the regulators of G-protein-signalling (RGS) domain of RGS4 and reciprocally regulate its action.
The Biochemical journal 2005;385(Pt 1):65-73.
2004: Hiroshi Hibino; Akikazu Fujita; Kaori Iwai; Mitsuhiko Yamada; Yoshihisa Kurachi
Differential assembly of inwardly rectifying K+ channel subunits, Kir4.1 and Kir5.1, in brain astrocytes.
The Journal of biological chemistry 2004;279(42):44065-73.
2004: Mitsuhiko Yamada; Masaru Ishii; Hiroshi Hibino; Yoshihisa Kurachi
Mutation in nucleotide-binding domains of sulfonylurea receptor 2 evokes Na-ATP-dependent activation of ATP-sensitive K+ channels: implication for dimerization of nucleotide-binding domains to induce channel opening.
Molecular pharmacology 2004;66(4):807-16.
2004: Kenji Tsujimae; Shingo Suzuki; Mitsuhiko Yamada; Yoshihisa Kurachi
Comparison of kinetic properties of quinidine and dofetilide block of HERG channels.
European journal of pharmacology 2004;493(1-3):29-40.
2004: Mitsuhiko Yamada; Yoshihisa Kurachi
The nucleotide-binding domains of sulfonylurea receptor 2A and 2B play different functional roles in nicorandil-induced activation of ATP-sensitive K+ channels.
Molecular pharmacology 2004;65(5):1198-207.
2004: Yoshihisa Kurachi; Masaru Ishii
Cell signal control of the G protein-gated potassium channel and its subcellular localization.
The Journal of physiology 2004;554(Pt 2):285-94.
2004: Masaru Ishii; Yoshihisa Kurachi
Assays of RGS protein modulation by phosphatidylinositides and calmodulin.
Methods in enzymology 2004;389():105-18.
2004: Hiroshi Hibino; Kayoko Higashi-Shingai; Akikazu Fujita; Kaori Iwai; Masaru Ishii; Yoshihisa Kurachi
Expression of an inwardly rectifying K+ channel, Kir5.1, in specific types of fibrocytes in the cochlear lateral wall suggests its functional importance in the establishment of endocochlear potential.
The European journal of neuroscience 2004;19(1):76-84.
2003: Masaru Ishii; Yoshihisa Kurachi
Physiological actions of regulators of G-protein signaling (RGS) proteins.
Life sciences 2003;74(2-3):163-71.
2003: Masaru Ishii; Akikazu Fujita; Kaori Iwai; Shunji Kusaka; Kayoko Higashi; Atsushi Inanobe; Hiroshi Hibino; Yoshihisa Kurachi
Differential expression and distribution of Kir5.1 and Kir4.1 inwardly rectifying K+ channels in retina.
American journal of physiology. Cell physiology 2003;285(2):C260-7.
2003: Yoshihisa Kurachi; Hiroshi Hibino
[Molecular dynamics of K+ transport and its crucial involvement in signal transduction].
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 2003;23(3):135-8.
2003: Motohiko Chachin; Mitsuhiko Yamada; Akikazu Fujita; Tetsuro Matsuoka; Kenji Matsushita; Yoshihisa Kurachi
Nateglinide, a D-phenylalanine derivative lacking either a sulfonylurea or benzamido moiety, specifically inhibits pancreatic beta-cell-type K(ATP) channels.
The Journal of pharmacology and experimental therapeutics 2003;304(3):1025-32.
2002: Masaru Ishii; Yoshihisa Kurachi
The 14-3-3 protein as a novel regulator of ion channel localisation.
The Journal of physiology 2002;545(Pt 1):2.
2002: Hironori Saito; Masato Kimura; Atsushi Inanobe; Toru Ohe; Yoshihisa Kurachi
An N-terminal sequence specific for a novel Homer1 isoform controls trafficking of group I metabotropic glutamate receptor in mammalian cells.
Biochemical and biophysical research communications 2002;296(3):523-9.
2002: Tetsuro Matsuoka; Yoshihisa Kurachi
[Molecular biology of ion channels in the heart].
Nihon rinsho. Japanese journal of clinical medicine 2002;60(7):1292-8.
2002: Motohiko Chachin; Yoshihisa Kurachi
[Evaluation of pro-arrhythmic risk of drugs due to QT interval prolongation by the HERG expression system].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 2002;119(6):345-51.
2002: Atsushi Inanobe; Akikazu Fujita; Minoru Ito; Hitonobu Tomoike; Kiyoshi Inageda; Yoshihisa Kurachi
Inward rectifier K+ channel Kir2.3 is localized at the postsynaptic membrane of excitatory synapses.
American journal of physiology. Cell physiology 2002;282(6):C1396-403.
2002: Masayuki Tanemoto; Akikazu Fujita; Kayoko Higashi; Yoshihisa Kurachi
PSD-95 mediates formation of a functional homomeric Kir5.1 channel in the brain.
Neuron 2002;34(3):387-97.
2002: Masaru Ishii; Atsushi Inanobe; Yoshihisa Kurachi
PIP3 inhibition of RGS protein and its reversal by Ca2+/calmodulin mediate voltage-dependent control of the G protein cycle in a cardiac K+ channel.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4325-30.
2002: Hidehiko Kondo; Iichiro Shimomura; Ken Kishida; Hiroshi Kuriyama; Yasunaka Makino; Hitoshi Nishizawa; Morihiro Matsuda; Norikazu Maeda; Hiroyuki Nagaretani; Shinji Kihara; Yoshihisa Kurachi; Tadashi Nakamura; Tohru Funahashi; Yuji Matsuzawa
Human aquaporin adipose (AQPap) gene. Genomic structure, promoter analysis and functional mutation.
European journal of biochemistry / FEBS 2002;269(7):1814-26.
2002: Akikazu Fujita; Yoshiyuki Horio; Kayoko Higashi; Tomoyoshi Mouri; Fumiaki Hata; Noriaki Takeguchi; Yoshihisa Kurachi
Specific localization of an inwardly rectifying K(+) channel, Kir4.1, at the apical membrane of rat gastric parietal cells; its possible involvement in K(+) recycling for the H(+)-K(+)-pump.
The Journal of physiology 2002;540(Pt 1):85-92.
2002: Kenji Matsushita; Kengo Kinoshita; Tetsuro Matsuoka; Akikazu Fujita; Takashi Fujikado; Yasuo Tano; Haruki Nakamura; Yoshihisa Kurachi
Intramolecular interaction of SUR2 subtypes for intracellular ADP-Induced differential control of K(ATP) channels.
Circulation research 2002;90(5):554-61.
2001: Masaru Ishii; Atsushi Inanobe; Satoru Fujita; Y Makino; Y Hosoya; Yoshihisa Kurachi
Ca(2+) elevation evoked by membrane depolarization regulates G protein cycle via RGS proteins in the heart.
Circulation research 2001;89(11):1045-50.
2001: Ken Kishida; Iichiro Shimomura; Hidehiko Kondo; Hiroshi Kuriyama; Y Makino; Hitoshi Nishizawa; Norikazu Maeda; Morihiro Matsuda; Noriyuki Ouchi; Shinji Kihara; Yoshihisa Kurachi; Tohru Funahashi; Yuji Matsuzawa
Genomic structure and insulin-mediated repression of the aquaporin adipose (AQPap), adipose-specific glycerol channel.
The Journal of biological chemistry 2001;276(39):36251-60.
2001: Akikazu Fujita; Tetsuro Matsuoka; Kenji Matsushita; Yoshihisa Kurachi
[Activation of ATP-sensitive K+ channels by ADP and K+ channel openers: homology model of sulfonylurea receptor carboxyl-termini].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 2001;118(3):177-86.
2001: Kayoko Higashi; Akikazu Fujita; Atsushi Inanobe; Masayuki Tanemoto; Katsumi Doi; Tateki Kubo; Yoshihisa Kurachi
An inwardly rectifying K(+) channel, Kir4.1, expressed in astrocytes surrounds synapses and blood vessels in brain.
American journal of physiology. Cell physiology 2001;281(3):C922-31.
2001: Atsushi Inanobe; Satoru Fujita; Y Makino; Kenji Matsushita; Masaru Ishii; Motohiko Chachin; Yoshihisa Kurachi
Interaction between the RGS domain of RGS4 with G protein alpha subunits mediates the voltage-dependent relaxation of the G protein-gated potassium channel.
The Journal of physiology 2001;535(Pt 1):133-43.
2001: Shunji Kusaka; Atsushi Inanobe; Akikazu Fujita; Y Makino; Masayuki Tanemoto; Kenji Matsushita; Yasuo Tano; Yoshihisa Kurachi
Functional Kir7.1 channels localized at the root of apical processes in rat retinal pigment epithelium.
The Journal of physiology 2001;531(Pt 1):27-36.
2000: Tetsuro Matsuoka; Kenji Matsushita; Y Katayama; Akikazu Fujita; Kiyoshi Inageda; Masayuki Tanemoto; Atsushi Inanobe; Shizuya Yamashita; Yuji Matsuzawa; Yoshihisa Kurachi
C-terminal tails of sulfonylurea receptors control ADP-induced activation and diazoxide modulation of ATP-sensitive K(+) channels.
Circulation research 2000;87(10):873-80.
2000: Satoru Fujita; Atsushi Inanobe; Motohiko Chachin; Y Aizawa; Yoshihisa Kurachi
A regulator of G protein signalling (RGS) protein confers agonist-dependent relaxation gating to a G protein-gated K+ channel.
The Journal of physiology 2000;526 Pt 2():341-7.
2000: Y Katayama; Akikazu Fujita; T Ohe; I Findlay; Yoshihisa Kurachi
Inhibitory effects of vesnarinone on cloned cardiac delayed rectifier K(+) channels expressed in a mammalian cell line.
The Journal of pharmacology and experimental therapeutics 2000;294(1):339-46.
2000: Masayuki Tanemoto; N Kittaka; Atsushi Inanobe; Yoshihisa Kurachi
In vivo formation of a proton-sensitive K+ channel by heteromeric subunit assembly of Kir5.1 with Kir4.1.
The Journal of physiology 2000;525 Pt 3():587-92.
2000: A Fujita; Yoshihisa Kurachi
SAP family proteins.
Biochemical and biophysical research communications 2000;269(1):1-6.
2000: Hiroshi Hibino; Atsushi Inanobe; Masayuki Tanemoto; Akikazu Fujita; Katsumi Doi; Tateki Kubo; Yoshio Hata; Yoshimi Takai; Yoshihisa Kurachi
Anchoring proteins confer G protein sensitivity to an inward-rectifier K(+) channel through the GK domain.
The EMBO journal 2000;19(1):78-83.
2000: Akikazu Fujita; Yoshihisa Kurachi
Molecular aspects of ATP-sensitive K+ channels in the cardiovascular system and K+ channel openers.
Pharmacology & therapeutics 2000;85(1):39-53.
2000: T Shindo; Y Katayama; Yoshiyuki Horio; Yoshihisa Kurachi
MCC-134, a novel vascular relaxing agent, is an inverse agonist for the pancreatic-type ATP-sensitive K(+) channel.
The Journal of pharmacology and experimental therapeutics 2000;292(1):131-5.
1999: Atsushi Inanobe; Yoshiyuki Horio; Akikazu Fujita; Masayuki Tanemoto; Hiroshi Hibino; Kiyoshi Inageda; Yoshihisa Kurachi
Molecular cloning and characterization of a novel splicing variant of the Kir3.2 subunit predominantly expressed in mouse testis.
The Journal of physiology 1999;521 Pt 1():19-30.
1999: Akikazu Fujita; Yoshiyuki Horio; Søren Nielsen; Erlend A Nagelhus; F Hata; Ole Petter Ottersen; Yoshihisa Kurachi
High-resolution immunogold cytochemistry indicates that AQP4 is concentrated along the basal membrane of parietal cell in rat stomach.
FEBS letters 1999;459(3):305-9.
1999: Shunji Kusaka; Yoshiyuki Horio; Akikazu Fujita; Kenji Matsushita; Atsushi Inanobe; Takahiro Gotow; Yasuo Uchiyama; Yasuo Tano; Yoshihisa Kurachi
Expression and polarized distribution of an inwardly rectifying K+ channel, Kir4.1, in rat retinal pigment epithelium.
The Journal of physiology 1999;520 Pt 2():373-81.
1999: Hiroshi Hibino; Yoshiyuki Horio; Akikazu Fujita; Atsushi Inanobe; Katsumi Doi; Takahiro Gotow; Yasuo Uchiyama; Tateki Kubo; Yoshihisa Kurachi
Expression of an inwardly rectifying K(+) channel, Kir4.1, in satellite cells of rat cochlear ganglia.
The American journal of physiology 1999;277(4 Pt 1):C638-44.
1999: VP Repunte; Haruki Nakamura; Akikazu Fujita; Yoshiyuki Horio; I Findlay; L Pott; Yoshihisa Kurachi
Extracellular links in Kir subunits control the unitary conductance of SUR/Kir6.0 ion channels.
The EMBO journal 1999;18(12):3317-24.
1999: Ken-ichirou Morishige; Atsushi Inanobe; Y Yoshimoto; Hirohisa Kurachi; Yuji Murata; Y Tokunaga; Takashi Maeda; Y Maruyama; Yoshihisa Kurachi
Secretagogue-induced exocytosis recruits G protein-gated K+ channels to plasma membrane in endocrine cells.
The Journal of biological chemistry 1999;274(12):7969-74.
1999: Erlend A Nagelhus; Yoshiyuki Horio; Atsushi Inanobe; Akikazu Fujita; Finn-Mogens Haug; Søren Nielsen; Yoshihisa Kurachi; Ole Petter Ottersen
Immunogold evidence suggests that coupling of K+ siphoning and water transport in rat retinal Müller cells is mediated by a coenrichment of Kir4.1 and AQP4 in specific membrane domains.
Glia 1999;26(1):47-54.
1999: Y Yoshimoto; Y Fukuyama; Yoshiyuki Horio; Atsushi Inanobe; M Gotoh; Yoshihisa Kurachi
Somatostatin induces hyperpolarization in pancreatic islet alpha cells by activating a G protein-gated K+ channel.
FEBS letters 1999;444(2-3):265-9.
1999: Atsushi Inanobe; Y Yoshimoto; Yoshiyuki Horio; Ken-ichirou Morishige; Hiroshi Hibino; S Matsumoto; Y Tokunaga; Takashi Maeda; Yoshio Hata; Yoshimi Takai; Yoshihisa Kurachi
Characterization of G-protein-gated K+ channels composed of Kir3.2 subunits in dopaminergic neurons of the substantia nigra.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(3):1006-17.
1998: Masashi Yamada; Atsushi Inanobe; Yoshihisa Kurachi
G protein regulation of potassium ion channels.
Pharmacological reviews 1998;50(4):723-60.
1998: Akikazu Fujita; Yoshiyuki Horio; Neal G Copeland; DJ Gilbert; NA Jenkins; Yoshihisa Kurachi
Assignment of mouse cardiac two-pore background K+ channel gene (Kcnk4) to the proximal region of mouse chromosome 5.
Genomics 1998;54(1):183-4.
1998: Tomoyoshi Mouri; N Kittaka; Yoshiyuki Horio; Neal G Copeland; DJ Gilbert; NA Jenkins; Yoshihisa Kurachi
Assignment of mouse inwardly rectifying potassium channel Kcnj16 to the distal region of mouse chromosome 11.
Genomics 1998;54(1):181-2.
1998: Yoshihisa Kurachi
[ATP-sensitive K+ channels of the cardiovascular system].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1998;112 Suppl 1():32P-35P.
1998: E Satoh; Masashi Yamada; C Kondo; VP Repunte; Yoshiyuki Horio; T Iijima; Yoshihisa Kurachi
Intracellular nucleotide-mediated gating of SUR/Kir6.0 complex potassium channels expressed in a mammalian cell line and its modification by pinacidil.
The Journal of physiology 1998;511 ( Pt 3)():663-74.
1998: T Shindo; Masashi Yamada; S Isomoto; Yoshiyuki Horio; Yoshihisa Kurachi
SUR2 subtype (A and B)-dependent differential activation of the cloned ATP-sensitive K+ channels by pinacidil and nicorandil.
British journal of pharmacology 1998;124(5):985-91.
1998: Y Okuyama; Masashi Yamada; C Kondo; E Satoh; S Isomoto; T Shindo; Yoshiyuki Horio; Masafumi Kitakaze; Masatsugu Hori; Yoshihisa Kurachi
The effects of nucleotides and potassium channel openers on the SUR2A/Kir6.2 complex K+ channel expressed in a mammalian cell line, HEK293T cells.
Pflügers Archiv : European journal of physiology 1998;435(5):595-603.
1998: D Kim; Akikazu Fujita; Yoshiyuki Horio; Yoshihisa Kurachi
Cloning and functional expression of a novel cardiac two-pore background K+ channel (cTBAK-1).
Circulation research 1998;82(4):513-8.
1998: Yasuharu Ohta; Yukio Tanizawa; H Inoue; T Hosaka; K Ueda; Akira Matsutani; VP Repunte; Masashi Yamada; Yoshihisa Kurachi; J Bryan; Lydia Aguilar-Bryan; M Alan Permutt; Yoshitomo Oka
Identification and functional analysis of sulfonylurea receptor 1 variants in Japanese patients with NIDDM.
Diabetes 1998;47(3):476-81.
1998: Y Tada; Yoshiyuki Horio; Yoshihisa Kurachi
Inwardly rectifying K+ channel in retinal Müller cells: comparison with the KAB-2/Kir4.1 channel expressed in HEK293T cells.
The Japanese journal of physiology 1998;48(1):71-80.
1998: C Kondo; VP Repunte; E Satoh; Masashi Yamada; Yoshiyuki Horio; Yuji Matsuzawa; L Pott; Yoshihisa Kurachi
Chimeras of Kir6.1 and Kir6.2 reveal structural elements involved in spontaneous opening and unitary conductance of the ATP-sensitive K+ channels.
Receptors & channels 1998;6(2):129-40.
1997: S Isomoto; Yoshihisa Kurachi
Function, regulation, pharmacology, and molecular structure of ATP-sensitive K+ channels in the cardiovascular system.
Journal of cardiovascular electrophysiology 1997;8(12):1431-46.
1997: Y Tada; Yoshiyuki Horio; T Takumi; Motokazu Terayama; Lyuji Tsuji; Neal G Copeland; NA Jenkins; Yoshihisa Kurachi
Assignment of the glial inwardly rectifying potassium channel KAB-2/Kir4.1 (Kcnj10) gene to the distal region of mouse chromosome 1.
Genomics 1997;45(3):629-30.
1997: Masaru Ishii; Yoshiyuki Horio; Y Tada; Hiroshi Hibino; Atsushi Inanobe; Minoru Ito; Masashi Yamada; Takahiro Gotow; Yasuo Uchiyama; Yoshihisa Kurachi
Expression and clustered distribution of an inwardly rectifying potassium channel, KAB-2/Kir4.1, on mammalian retinal Müller cell membrane: their regulation by insulin and laminin signals.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(20):7725-35.
1997: S Isomoto; Yoshiyuki Horio; S Matsumoto; C Kondo; Masashi Yamada; DJ Gilbert; Neal G Copeland; NA Jenkins; Yoshihisa Kurachi
Sur2 and Kcnj8 genes are tightly linked on the distal region of mouse chromosome 6.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(10):790-1.
1997: Ken-ichirou Morishige; T Takumi; Noriko Takahashi; H Koyama; Hirohisa Kurachi; A Miyake; Yuji Murata; Neal G Copeland; DJ Gilbert; NA Jenkins; Yoshihisa Kurachi
Assignment of the murine inwardly rectifying potassium channel IRK3 gene (Kcnj4) to the mouse chromosome 15.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(9):699-700.
1997: Hiroshi Hibino; Yoshiyuki Horio; Atsushi Inanobe; Katsumi Doi; Minoru Ito; Masashi Yamada; Takahiro Gotow; Yasuo Uchiyama; M Kawamura; Tateki Kubo; Yoshihisa Kurachi
An ATP-dependent inwardly rectifying potassium channel, KAB-2 (Kir4. 1), in cochlear stria vascularis of inner ear: its specific subcellular localization and correlation with the formation of endocochlear potential.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(12):4711-21.
1997: Yoshiyuki Horio; Hiroshi Hibino; Atsushi Inanobe; Masashi Yamada; Masaru Ishii; Y Tada; E Satoh; Yoshio Hata; Yoshimi Takai; Yoshihisa Kurachi
Clustering and enhanced activity of an inwardly rectifying potassium channel, Kir4.1, by an anchoring protein, PSD-95/SAP90.
The Journal of biological chemistry 1997;272(20):12885-8.
1997: Masashi Yamada; S Isomoto; S Matsumoto; C Kondo; T Shindo; Yoshiyuki Horio; Yoshihisa Kurachi
Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive K+ channel.
The Journal of physiology 1997;499 ( Pt 3)():715-20.
1997: Y Horio; Yoshihisa Kurachi
[Potassium channels in glial cells].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1997;109(3):103-10.
1997: S Isomoto; C Kondo; Yoshihisa Kurachi
Inwardly rectifying potassium channels: their molecular heterogeneity and function.
The Japanese journal of physiology 1997;47(1):11-39.
1997: H Ito; H Tsuchimochi; Y Tada; Yoshihisa Kurachi
Phosphorylation-independent inhibition by intracellular cyclic nucleotides of brain inwardly rectifying K+ current expressed in Xenopus oocytes.
FEBS letters 1997;402(1):12-6.
1997: S Isomoto; Masashi Yamada; Yoshiyuki Horio; Yoshihisa Kurachi
Molecular aspects of ATP-sensitive K+ channels in the cardiovascular system.
The Japanese journal of physiology 1997;47 Suppl 1():S5-6.
1996: C Kondo; S Isomoto; S Matsumoto; Masashi Yamada; Yoshiyuki Horio; S Yamashita; K Takemura-Kameda; Yuji Matsuzawa; Yoshihisa Kurachi
Cloning and functional expression of a novel isoform of ROMK inwardly rectifying ATP-dependent K+ channel, ROMK6 (Kir1.1f).
FEBS letters 1996;399(1-2):122-6.
1996: Y Hosoya; M Yamada; H Ito; Yoshihisa Kurachi
A functional model for G protein activation of the muscarinic K+ channel in guinea pig atrial myocytes. Spectral analysis of the effect of GTP on single-channel kinetics.
The Journal of general physiology 1996;108(6):485-95.
1996: T Takumi; Lyuji Tsuji; C Kondo; N Takahashi; Ken-ichirou Morishige; Neal G Copeland; DJ Gilbert; NA Jenkins; Yoshihisa Kurachi
Assignment of the murine inward rectifier potassium channel Irk2 (Kir2.2) gene to the central region of mouse chromosome 11.
Genomics 1996;37(2):270-2.
1996: S Isomoto; C Kondo; Masashi Yamada; S Matsumoto; O Higashiguchi; Yoshiyuki Horio; Yuji Matsuzawa; Yoshihisa Kurachi
A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel.
The Journal of biological chemistry 1996;271(40):24321-4.
1996: S Isomoto; Yoshihisa Kurachi
[Molecular structure and expression of ion channels in the heart].
Nihon rinsho. Japanese journal of clinical medicine 1996;54(8):2056-65.
1996: M Ito; Atsushi Inanobe; Yoshiyuki Horio; Hiroshi Hibino; S Isomoto; H Ito; K Mori; A Tonosaki; H Tomoike; Yoshihisa Kurachi
Immunolocalization of an inwardly rectifying K+ channel, K(AB)-2 (Kir4.1), in the basolateral membrane of renal distal tubular epithelia.
FEBS letters 1996;388(1):11-5.
1996: T Yamashita; Yoshiyuki Horio; Masashi Yamada; N Takahashi; C Kondo; Yoshihisa Kurachi
Competition between Mg2+ and spermine for a cloned IRK2 channel expressed in a human cell line.
The Journal of physiology 1996;493 ( Pt 1)():143-56.
1996: Ken-ichirou Morishige; Atsushi Inanobe; N Takahashi; Y Yoshimoto; Hirohisa Kurachi; A Miyake; Y Tokunaga; Takashi Maeda; Yoshihisa Kurachi
G protein-gated K+ channel (GIRK1) protein is expressed presynaptically in the paraventricular nucleus of the hypothalamus.
Biochemical and biophysical research communications 1996;220(2):300-5.
1996: S Isomoto; Yoshihisa Kurachi
[Molecular and biophysical aspects of potassium channels].
Nihon rinsho. Japanese journal of clinical medicine 1996;54(3):660-6.
1996: Yoshiyuki Horio; Ken-ichirou Morishige; N Takahashi; Yoshihisa Kurachi
Differential distribution of classical inwardly rectifying potassium channel mRNAs in the brain: comparison of IRK2 with IRK1 and IRK3.
FEBS letters 1996;379(3):239-43.
1996: S Isomoto; C Kondo; N Takahashi; S Matsumoto; Masashi Yamada; T Takumi; Yoshiyuki Horio; Yoshihisa Kurachi
A novel ubiquitously distributed isoform of GIRK2 (GIRK2B) enhances GIRK1 expression of the G-protein-gated K+ current in Xenopus oocytes.
Biochemical and biophysical research communications 1996;218(1):286-91.
1995: Atsushi Inanobe; H Ito; M Ito; Y Hosoya; Yoshihisa Kurachi
Immunological and physical characterization of the brain G protein-gated muscarinic potassium channel.
Biochemical and biophysical research communications 1995;217(3):1238-44.
1995: Masashi Yamada; Yoshihisa Kurachi; Y Hosoya; Atsushi Inanobe
[Molecular mechanism of the G protein regulation of inwardly rectifying potassium channels].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1995;40(15):2297-306.
1995: Yoshihisa Kurachi
G protein regulation of cardiac muscarinic potassium channel.
The American journal of physiology 1995;269(4 Pt 1):C821-30.
1995: Masashi Yamada; Yoshihisa Kurachi
Spermine gates inward-rectifying muscarinic but not ATP-sensitive K+ channels in rabbit atrial myocytes. Intracellular substance-mediated mechanism of inward rectification.
The Journal of biological chemistry 1995;270(16):9289-94.