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John Kuriyan

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X Ray Crystallography

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TOP 3
Qingrong Yan; Patrick R Visperas; Arthur Weiss; Tiago Barros; Sebastian Deindl; Theresa A Kadlecek; John Kuriyan
Structural Basis for Activation of ZAP-70 by Phosphorylation of the SH2-Kinase Linker.
Nicholas F Endres; Jay T Groves; Yongjian Huang; Erika Kovacs; Jeffrey G Pelton; Yibing Shan; David E Shaw; Adam W Smith; David E Wemmer; Anton Arkhipov; Rahul Das; John Kuriyan
Conformational coupling across the plasma membrane in activation of the EGF receptor.
Catherine C Smith; KJ Travers; Qi Wang; Susana Wang; Patrick P Zarrinkar; Chen-Shan Chin; Lauren E Damon; Jeremy P Hunt; Andrew Kasarskis; John Kuriyan; Mark Levis; Alexander E Perl; Sara Salerno; Eric E Schadt; Neil P Shah
Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia.

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All Publications

2013: Qingrong Yan; Patrick R Visperas; Arthur Weiss; Tiago Barros; Sebastian Deindl; Theresa A Kadlecek; John Kuriyan
Structural Basis for Activation of ZAP-70 by Phosphorylation of the SH2-Kinase Linker.
Molecular and cellular biology 2013;33(11):2188-201.
2013: Nicholas F Endres; Jay T Groves; Yongjian Huang; Erika Kovacs; Jeffrey G Pelton; Yibing Shan; David E Shaw; Adam W Smith; David E Wemmer; Anton Arkhipov; Rahul Das; John Kuriyan
Conformational coupling across the plasma membrane in activation of the EGF receptor.
Cell 2013;152(3):543-56.
2012: Catherine C Smith; KJ Travers; Qi Wang; Susana Wang; Patrick P Zarrinkar; Chen-Shan Chin; Lauren E Damon; Jeremy P Hunt; Andrew Kasarskis; John Kuriyan; Mark Levis; Alexander E Perl; Sara Salerno; Eric E Schadt; Neil P Shah
Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia.
Nature 2012;485(7397):260-3.
2012: Brian A Kelch; Debora L Makino; Mike O'Donnell; John Kuriyan
Clamp loader ATPases and the evolution of DNA replication machinery.
BMC biology 2012;10():34.
2011: Nicholas F Endres; Kate Engel; Erika Kovacs; Rahul Das; John Kuriyan
Regulation of the catalytic activity of the EGF receptor.
Current opinion in structural biology 2011;21(6):777-84.
2011: Luke H Chao; Jay T Groves; Tanja Kortemme; Il-Hyung Lee; Joshua Levitz; Daniel J Mandell; Oren S Rosenberg; Howard Schulman; Margaret M Stratton; John Kuriyan
A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulin- dependent kinase II holoenzyme.
Cell 2011;146(5):732-45.
2011: Natalia Jura; Xuewu Zhang; Nicholas F Endres; Markus A Seeliger; Thomas Schindler; John Kuriyan
Catalytic control in the EGF receptor and its connection to general kinase regulatory mechanisms.
Molecular cell 2011;42(1):9-22.
2011: Katherine E Wickliffe; Sonja Lorenz; David E Wemmer; John Kuriyan; Michael Rape
The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2.
Cell 2011;144(5):769-81.
2010: Charles Olea; John Kuriyan; Michael A Marletta
Modulating heme redox potential through protein-induced porphyrin distortion.
Journal of the American Chemical Society 2010;132(37):12794-5.
2010: Jay T Groves; John Kuriyan
Molecular mechanisms in signal transduction at the membrane.
Nature structural & molecular biology 2010;17(6):659-65.
2010: Charles Olea; Mark A Herzik; John Kuriyan; Michael A Marletta
Structural insights into the molecular mechanism of H-NOX activation.
Protein science : a publication of the Protein Society 2010;19(4):881-7.
2010: Luke H Chao; Patricia Pellicena; Sebastian Deindl; Lauren A Barclay; Howard Schulman; John Kuriyan
Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation.
Nature structural & molecular biology 2010;17(3):264-72.
2010: Jodi Gureasko; Olga Kuchment; Debora Lika Makino; Holger Sondermann; Dafna Bar-Sagi; John Kuriyan
Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(8):3430-5.
2010: Randall McNally; Gregory D Bowman; Eric R Goedken; Mike O'Donnell; John Kuriyan
Analysis of the role of PCNA-DNA contacts during clamp loading.
BMC structural biology 2010;10():3.
2009: Natalia Jura; Yibing Shan; Xiaoxian Cao; David E Shaw; John Kuriyan
Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(51):21608-13.
2009: Sebastian Deindl; Theresa A Kadlecek; Xiaoxian Cao; John Kuriyan; Arthur Weiss
Stability of an autoinhibitory interface in the structure of the tyrosine kinase ZAP-70 impacts T cell receptor response.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(49):20699-704.
2009: Natalia Jura; Nicholas F Endres; Kate Engel; Sebastian Deindl; Rahul Das; Meindert H Lamers; David E Wemmer; Xuewu Zhang; John Kuriyan
Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment.
Cell 2009;137(7):1293-307.
2009: Kyle R Simonetta; Steven L Kazmirski; Eric R Goedken; Aaron J Cantor; Brian A Kelch; Randall McNally; Steven N Seyedin; Debora L Makino; Mike O'Donnell; John Kuriyan
The mechanism of ATP-dependent primer-template recognition by a clamp loader complex.
Cell 2009;137(4):659-71.
2009: Kathryn Elizabeth Muratore; Markus A Seeliger; Zhihong Wang; Dina Fomina; Johnathan Neiswinger; James J Havranek; David Baker; John Kuriyan; Philip A Cole
Comparative analysis of mutant tyrosine kinase chemical rescue.
Biochemistry 2009;48(15):3378-86.
2009: Markus A Seeliger; John Kuriyan
A MAPK scaffold lends a helping hand.
Cell 2009;136(6):994-6.
2009: Markus A Seeliger; Pratistha Ranjitkar; Corynn Kasap; Yibing Shan; David E Shaw; Neil P Shah; John Kuriyan; Dustin J Maly
Equally potent inhibition of c-Src and Abl by compounds that recognize inactive kinase conformations.
Cancer research 2009;69(6):2384-92.
2009: Tanya S Freedman; Holger Sondermann; Olga Kuchment; Gregory D Friedland; Tanja Kortemme; John Kuriyan
Differences in flexibility underlie functional differences in the Ras activators son of sevenless and Ras guanine nucleotide releasing factor 1.
Structure (London, England : 1993) 2009;17(1):41-53.
2009: Nicholas M Levinson; Patrick R Visperas; John Kuriyan
The tyrosine kinase Csk dimerizes through Its SH3 domain.
PloS one 2009;4(11):e7683.
2009: Jonathan A Winger; Oliver Hantschel; Giulio Superti-Furga; John Kuriyan
The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2).
BMC structural biology 2009;9():7.
2008: Charles Olea; Elizabeth M Boon; Patricia Pellicena; John Kuriyan; Michael A Marletta
Probing the function of heme distortion in the H-NOX family.
ACS chemical biology 2008;3(11):703-10.
2008: Mohammad Azam; Markus A Seeliger; Nathanael S Gray; John Kuriyan; George Q Daley
Activation of tyrosine kinases by mutation of the gatekeeper threonine.
Nature structural & molecular biology 2008;15(10):1109-18.
2008: Roxana E Georgescu; Olga Yurieva; Seung-Sup Kim; John Kuriyan; Xiang-Peng Kong; Mike O'Donnell
Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(32):11116-21.
2008: Nicholas M Levinson; Markus A Seeliger; Philip A Cole; John Kuriyan
Structural basis for the recognition of c-Src by its inactivator Csk.
Cell 2008;134(1):124-34.
2008: Jodi Gureasko; William J Galush; Sean Boykevisch; Holger Sondermann; Dafna Bar-Sagi; Jay T Groves; John Kuriyan
Membrane-dependent signal integration by the Ras activator Son of sevenless.
Nature structural & molecular biology 2008;15(5):452-61.
2008: Roxana E Georgescu; Seung-Sup Kim; Olga Yurieva; John Kuriyan; Xiang-Peng Kong; Mike O'Donnell
Structure of a sliding clamp on DNA.
Cell 2008;132(1):43-54.
2008: Jonathan A Winger; Emily R Derbyshire; Meindert H Lamers; Michael A Marletta; John Kuriyan
The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase.
BMC structural biology 2008;8():42.
2007: John Kuriyan; David Eisenberg
The origin of protein interactions and allostery in colocalization.
Nature 2007;450(7172):983-90.
2007: Xuewu Zhang; KERRY PAUMI; Ron Bose; Natalia Jura; Philip A Cole; John Kuriyan
Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface.
Nature 2007;450(7170):741-4.
2007: Sebastian Deindl; Theresa A Kadlecek; Tomas Brdicka; Xiaoxian Cao; Arthur Weiss; John Kuriyan
Structural basis for the inhibition of tyrosine kinase activity of ZAP-70.
Cell 2007;129(4):735-46.
2007: Markus A Seeliger; Bhushan Nagar; Filipp Frank; Xiaoxian Cao; M Nidanie Henderson; John Kuriyan
c-Src binds to the cancer drug imatinib with an inactive Abl/c-Kit conformation and a distributed thermodynamic penalty.
Structure (London, England : 1993) 2007;15(3):299-311.
2006: Patricia Pellicena; John Kuriyan
Protein-protein interactions in the allosteric regulation of protein kinases.
Current opinion in structural biology 2006;16(6):702-9.
2006: Aaron Johnson; Nina Y Yao; Gregory D Bowman; John Kuriyan; Mike O'Donnell
The replication factor C clamp loader requires arginine finger sensors to drive DNA binding and proliferating cell nuclear antigen loading.
The Journal of biological chemistry 2006;281(46):35531-43.
2006: Sean Boykevisch; Chen Zhao; Holger Sondermann; Polyxeni Philippidou; Simon Halegoua; John Kuriyan; Dafna Bar-Sagi
Regulation of ras signaling dynamics by Sos-mediated positive feedback.
Current biology : CB 2006;16(21):2173-9.
2006: Tanya S Freedman; Holger Sondermann; Gregory D Friedland; Tanja Kortemme; Dafna Bar-Sagi; Susan Marqusee; John Kuriyan
A Ras-induced conformational switch in the Ras activator Son of sevenless.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(45):16692-7.
2006: Meindert H Lamers; Roxana E Georgescu; Sang-Gyu Lee; Mike O'Donnell; John Kuriyan
Crystal structure of the catalytic alpha subunit of E. coli replicative DNA polymerase III.
Cell 2006;126(5):881-92.
2006: Michelle Pirruccello; Holger Sondermann; Jeffrey G Pelton; Patricia Pellicena; André Hoelz; Jonathan Chernoff; David E Wemmer; John Kuriyan
A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases.
Journal of molecular biology 2006;361(2):312-26.
2006: Nina Y Yao; Aaron Johnson; Greg D Bowman; John Kuriyan; Mike O'Donnell
Mechanism of proliferating cell nuclear antigen clamp opening by replication factor C.
The Journal of biological chemistry 2006;281(25):17528-39.
2006: Xuewu Zhang; Jodi Gureasko; Kui Shen; Philip A Cole; John Kuriyan
An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor.
Cell 2006;125(6):1137-49.
2006: Nicholas M Levinson; Olga Kuchment; Kui Shen; Matthew Adam Young; Michael Koldobskiy; Martin Karplus; Philip A Cole; John Kuriyan
A Src-like inactive conformation in the abl tyrosine kinase domain.
PLoS biology 2006;4(5):e144.
2006: Bhushan Nagar; Oliver Hantschel; Markus A Seeliger; Jason M Davies; William I Weis; Giulio Superti-Furga; John Kuriyan
Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase.
Molecular cell 2006;21(6):787-98.
2006: Yong-Sung Kim; Rashna Bhandari; Jennifer Cochran; John Kuriyan; K Dane Wittrup
Directed evolution of the epidermal growth factor receptor extracellular domain for expression in yeast.
Proteins 2006;62(4):1026-35.
2006: Oren S Rosenberg; Sebastian Deindl; Luis R Comolli; André Hoelz; Kenneth H Downing; Angus Nairn; John Kuriyan
Oligomerization states of the association domain and the holoenyzme of Ca2+/CaM kinase II.
The FEBS journal 2006;273(4):682-94.
2006: Mike O'Donnell; John Kuriyan
Clamp loaders and replication initiation.
Current opinion in structural biology 2006;16(1):35-41.
2006: Matthew Adam Young; Neil P Shah; Luke H Chao; Markus Seeliger; Zdravko V Milanov; William H Biggs; Daniel K Treiber; Hitesh K Patel; Patrick P Zarrinkar; David J Lockhart; Charles L Sawyers; John Kuriyan
Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680.
Cancer research 2006;66(2):1007-14.
2006: Maria A Argiriadi; Eric R Goedken; Irina Bruck; Mike O'Donnell; John Kuriyan
Crystal structure of a DNA polymerase sliding clamp from a Gram-positive bacterium.
BMC structural biology 2006;6():2.
2005: Oren S Rosenberg; Sebastian Deindl; Rou-Jia Sung; Angus Nairn; John Kuriyan
Structure of the autoinhibited kinase domain of CaMKII and SAXS analysis of the holoenzyme.
Cell 2005;123(5):849-60.
2005: Markus A Seeliger; Matthew Adam Young; M Nidanie Henderson; Patricia Pellicena; David S King; Arnold M Falick; John Kuriyan
High yield bacterial expression of active c-Abl and c-Src tyrosine kinases.
Protein science : a publication of the Protein Society 2005;14(12):3135-9.
2005: Holger Sondermann; Bhushan Nagar; Dafna Bar-Sagi; John Kuriyan
Computational docking and solution x-ray scattering predict a membrane-interacting role for the histone domain of the Ras activator son of sevenless.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(46):16632-7.
2005: Steven L Kazmirski; Yanxiang Zhao; Gregory D Bowman; Mike O'Donnell; John Kuriyan
Out-of-plane motions in open sliding clamps: molecular dynamics simulations of eukaryotic and archaeal proliferating cell nuclear antigen.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(39):13801-6.
2005: Martin Karplus; John Kuriyan
Molecular dynamics and protein function.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(19):6679-85.
2005: Holger Sondermann; John Kuriyan
C2 can do it, too.
Cell 2005;121(2):158-60.
2005: Gregory D Bowman; Eric R Goedken; Steven L Kazmirski; Mike O'Donnell; John Kuriyan
DNA polymerase clamp loaders and DNA recognition.
FEBS letters 2005;579(4):863-7.
2005: Bhushan Nagar; John Kuriyan
SAXS and the working protein.
Structure (London, England : 1993) 2005;13(2):169-70.
2005: Eric R Goedken; Steven L Kazmirski; Gregory D Bowman; Mike O'Donnell; John Kuriyan
Mapping the interaction of DNA with the Escherichia coli DNA polymerase clamp loader complex.
Nature structural & molecular biology 2005;12(2):183-90.
2004: Steven L Kazmirski; Marjetka Podobnik; Tanya F Weitze; Mike O'Donnell; John Kuriyan
Structural analysis of the inactive state of the Escherichia coli DNA polymerase clamp-loader complex.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(48):16750-5.
2004: Holger Sondermann; Stephen M Soisson; Sean Boykevisch; Shao-Song Yang; Dafna Bar-Sagi; John Kuriyan
Structural analysis of autoinhibition in the Ras activator Son of sevenless.
Cell 2004;119(3):393-405.
2004: Patricia Pellicena; David S Karow; Elizabeth M Boon; Michael A Marletta; John Kuriyan
Crystal structure of an oxygen-binding heme domain related to soluble guanylate cyclases.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(35):12854-9.
2004: Gregory D Bowman; Mike O'Donnell; John Kuriyan
Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex.
Nature 2004;429(6993):724-30.
2004: Eric R Goedken; Marcia Levitus; Aaron Johnson; Carlos Bustamante; Mike O'Donnell; John Kuriyan
Fluorescence measurements on the E.coli DNA polymerase clamp loader: implications for conformational changes during ATP and clamp binding.
Journal of molecular biology 2004;336(5):1047-59.
2004: John Kuriyan
Allostery and coupled sequence variation in nuclear hormone receptors.
Cell 2004;116(3):354-6.
2004: Gabriel Waksman; John Kuriyan
Structure and specificity of the SH2 domain.
Cell 2004;116(2 Suppl):S45-8, 3 p following S48.
2004: Jacqueline M Gulbis; Steven L Kazmirski; Jeff Finkelstein; Zvi Kelman; Mike O'Donnell; John Kuriyan
Crystal structure of the chi:psi sub-assembly of the Escherichia coli DNA polymerase clamp-loader complex.
European journal of biochemistry / FEBS 2004;271(2):439-49.
2003: Holger Sondermann; Stephen M Soisson; Dafna Bar-Sagi; John Kuriyan
Tandem histone folds in the structure of the N-terminal segment of the ras activator Son of Sevenless.
Structure (London, England : 1993) 2003;11(12):1583-93.
2003: André Hoelz; Angus Nairn; John Kuriyan
Crystal structure of a tetradecameric assembly of the association domain of Ca2+/calmodulin-dependent kinase II.
Molecular cell 2003;11(5):1241-51.
2003: Bhushan Nagar; Oliver Hantschel; Matthew Adam Young; Klaus Scheffzek; Darren R Veach; William G Bornmann; Bayard Clarkson; Giulio Superti-Furga; John Kuriyan
Structural basis for the autoinhibition of c-Abl tyrosine kinase.
Cell 2003;112(6):859-71.
2003: Oliver Hantschel; Bhushan Nagar; Sebastian Guettler; Jana Kretzschmar; Karel Dorey; John Kuriyan; Giulio Superti-Furga
A myristoyl/phosphotyrosine switch regulates c-Abl.
Cell 2003;112(6):845-57.
2003: S Mariana Margarit; Holger Sondermann; Brian E Hall; Bhushan Nagar; André Hoelz; Michelle Pirruccello; Dafna Bar-Sagi; John Kuriyan
Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS.
Cell 2003;112(5):685-95.
2003: Marjetka Podobnik; Tanya F Weitze; Mike O'Donnell; John Kuriyan
Nucleotide-induced conformational changes in an isolated Escherichia coli DNA polymerase III clamp loader subunit.
Structure (London, England : 1993) 2003;11(3):253-63.
2003: Xiaomin Chen; Rashna Bhandari; Uwe Vinkemeier; Focco Van Den Akker; James E Darnell; John Kuriyan
A reinterpretation of the dimerization interface of the N-terminal domains of STATs.
Protein science : a publication of the Protein Society 2003;12(2):361-5.
2002: Megan J Davey; David Jeruzalmi; John Kuriyan; Mike O'Donnell
Motors and switches: AAA+ machines within the replisome.
Nature reviews. Molecular cell biology 2002;3(11):826-35.
2002: Neil P Shah; John M Nicoll; Bhushan Nagar; Mercedes E Gorre; Ronald L Paquette; John Kuriyan; Charles L Sawyers
Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia.
Cancer cell 2002;2(2):117-25.
2002: David Wisniewski; Caryl L Lambek; Chongyuan Liu; Annabel Strife; Darren R Veach; Bhushan Nagar; Matthew Adam Young; Thomas Schindler; William G Bornmann; Joseph R Bertino; John Kuriyan; Bayard Clarkson
Characterization of potent inhibitors of the Bcr-Abl and the c-kit receptor tyrosine kinases.
Cancer research 2002;62(15):4244-55.
2002: Bhushan Nagar; William G Bornmann; Patricia Pellicena; Thomas Schindler; Darren R Veach; W Todd Miller; Bayard Clarkson; John Kuriyan
Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571).
Cancer research 2002;62(15):4236-43.
2002: Irina Bruck; Alexander Yuzhakov; Olga Yurieva; David Jeruzalmi; Maija Skangalis; John Kuriyan; Mike O'Donnell
Analysis of a multicomponent thermostable DNA polymerase III replicase from an extreme thermophile.
The Journal of biological chemistry 2002;277(19):17334-48.
2002: Morgan Huse; John Kuriyan
The conformational plasticity of protein kinases.
Cell 2002;109(3):275-82.
2002: David Jeruzalmi; Mike O'Donnell; John Kuriyan
Clamp loaders and sliding clamps.
Current opinion in structural biology 2002;12(2):217-24.
2002: Robert R Flavell; Morgan Huse; Mike Goger; Michelle Trester-Zedlitz; John Kuriyan; Tom W Muir
Efficient semisynthesis of a tetraphosphorylated analogue of the Type I TGFbeta receptor.
Organic letters 2002;4(2):165-8.
2002: David S Eisenberg; John Kuriyan; Frederic M Richards
John T. Edsall and Advances in Protein Chemistry.
Advances in protein chemistry 2002;62():xi-xiv.
2001: Mike O'Donnell; David Jeruzalmi; John Kuriyan
Clamp loader structure predicts the architecture of DNA polymerase III holoenzyme and RFC.
Current biology : CB 2001;11(22):R935-46.
2001: Morgan Huse; Tom W Muir; Lan Xu; Y G Chen; John Kuriyan; Joan Massagué
The TGF beta receptor activation process: an inhibitor- to substrate-binding switch.
Molecular cell 2001;8(3):671-82.
2001: David Jeruzalmi; Mike O'Donnell; John Kuriyan
Crystal structure of the processivity clamp loader gamma (gamma) complex of E. coli DNA polymerase III.
Cell 2001;106(4):429-41.
2001: David Jeruzalmi; Olga Yurieva; Y Zhao; Matthew Adam Young; J Stewart; Manju M Hingorani; Mike O'Donnell; John Kuriyan
Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III.
Cell 2001;106(4):417-28.
2001: Brian E Hall; S S Yang; P A Boriack-Sjodin; John Kuriyan; Dafna Bar-Sagi
Structure-based mutagenesis reveals distinct functions for Ras switch 1 and switch 2 in Sos-catalyzed guanine nucleotide exchange.
The Journal of biological chemistry 2001;276(29):27629-37.
2001: H Yamaguchi; M Matsushita; Angus Nairn; John Kuriyan
Crystal structure of the atypical protein kinase domain of a TRP channel with phosphotransferase activity.
Molecular cell 2001;7(5):1047-57.
2001: Matthew Adam Young; S Gonfloni; Giulio Superti-Furga; Benoît Roux; John Kuriyan
Dynamic coupling between the SH2 and SH3 domains of c-Src and Hck underlies their inactivation by C-terminal tyrosine phosphorylation.
Cell 2001;105(1):115-26.
2000: Thomas Schindler; William G Bornmann; Patricia Pellicena; W Todd Miller; Bayard Clarkson; John Kuriyan
Structural mechanism for STI-571 inhibition of abelson tyrosine kinase.
Science (New York, N.Y.) 2000;289(5486):1938-42.
2000: Paul B Sigler; G S Stein; A L Boskey; N D Jones; John Kuriyan; W M Miller; M L Shuler; Bi-Cheng Wang
Cell science and protein crystal growth research for the International Space Station.
Journal of cellular biochemistry 2000;79(4):662-71.
2000: Marjetka Podobnik; Peter McInerney; Mike O'Donnell; John Kuriyan
A TOPRIM domain in the crystal structure of the catalytic core of Escherichia coli primase confirms a structural link to DNA topoisomerases.
Journal of molecular biology 2000;300(2):353-62.
2000: David Jeruzalmi; John Kuriyan; Jennifer A Doudna
Paul Sigler (1934-2000).
Trends in biochemical sciences 2000;25(5):221-2.
2000: E Conti; John Kuriyan
Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha.
Structure (London, England : 1993) 2000;8(3):329-38.
2000: Ismail Moarefi; David Jeruzalmi; J Turner; Mike O'Donnell; John Kuriyan
Crystal structure of the DNA polymerase processivity factor of T4 bacteriophage.
Journal of molecular biology 2000;296(5):1215-23.
2000: M Porter; T Schindler; John Kuriyan; W T Miller
Reciprocal regulation of Hck activity by phosphorylation of Tyr(527) and Tyr(416). Effect of introducing a high affinity intramolecular SH2 ligand.
The Journal of biological chemistry 2000;275(4):2721-6.
1999: Andrej Sali; John Kuriyan
Challenges at the frontiers of structural biology.
Trends in cell biology 1999;9(12):M20-4.
1999: Y Zhao; David Jeruzalmi; Ismail Moarefi; L Leighton; R Lasken; John Kuriyan
Crystal structure of an archaebacterial DNA polymerase.
Structure (London, England : 1993) 1999;7(10):1189-99.
1999: T Schindler; F Sicheri; A Pico; A Gazit; A Levitzki; John Kuriyan
Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor.
Molecular cell 1999;3(5):639-48.
1999: Morgan Huse; Y G Chen; Joan Massagué; John Kuriyan
Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12.
Cell 1999;96(3):425-36.
1998: M LaFevre-Bernt; F Sicheri; A Pico; M Porter; John Kuriyan; W Todd Miller
Intramolecular regulatory interactions in the Src family kinase Hck probed by mutagenesis of a conserved tryptophan residue.
The Journal of biological chemistry 1998;273(48):32129-34.
1998: Stephen M Soisson; Anjaruwee Nimnual; M Uy; Dafna Bar-Sagi; John Kuriyan
Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein.
Cell 1998;95(2):259-68.
1998: E Conti; M Uy; L Leighton; Günter Blobel; John Kuriyan
Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell 1998;94(2):193-204.
1998: P A Boriack-Sjodin; S Mariana Margarit; Dafna Bar-Sagi; John Kuriyan
The structural basis of the activation of Ras by Sos.
Nature 1998;394(6691):337-43.
1998: Xiaomin Chen; Uwe Vinkemeier; Y Zhao; David Jeruzalmi; James E Darnell; John Kuriyan
Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA.
Cell 1998;93(5):827-39.
1998: Uwe Vinkemeier; Ismail Moarefi; James E Darnell; John Kuriyan
Structure of the amino-terminal protein interaction domain of STAT-4.
Science (New York, N.Y.) 1998;279(5353):1048-52.
1998: C H Lee; David Cowburn; John Kuriyan
Peptide recognition mechanisms of eukaryotic signaling modules.
Methods in molecular biology (Clifton, N.J.) 1998;84():3-31.
1997: F Sicheri; John Kuriyan
Structures of Src-family tyrosine kinases.
Current opinion in structural biology 1997;7(6):777-85.
1997: B Guenther; R Onrust; Andrej Sali; Mike O'Donnell; John Kuriyan
Crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III.
Cell 1997;91(3):335-45.
1997: Olga Yurieva; Maija Skangalis; John Kuriyan; Mike O'Donnell
Thermus thermophilis dnaX homolog encoding gamma- and tau-like proteins of the chromosomal replicase.
The Journal of biological chemistry 1997;272(43):27131-9.
1997: Z Zhang; C H Lee; Valsan Mandiyan; Jean-Paul Borg; Benjamin L Margolis; Joseph Schlessinger; John Kuriyan
Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.
The EMBO journal 1997;16(20):6141-50.
1997: C J Harrison; M Hayer-Hartl; M Di Liberto; F Hartl; John Kuriyan
Crystal structure of the nucleotide exchange factor GrpE bound to the ATPase domain of the molecular chaperone DnaK.
Science (New York, N.Y.) 1997;276(5311):431-5.
1997: Ismail Moarefi; M LaFevre-Bernt; F Sicheri; Morgan Huse; C H Lee; John Kuriyan; W Todd Miller
Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement.
Nature 1997;385(6617):650-3.
1997: F Sicheri; Ismail Moarefi; John Kuriyan
Crystal structure of the Src family tyrosine kinase Hck.
Nature 1997;385(6617):602-9.
1997: E Gibbs; Zvi Kelman; Jacqueline M Gulbis; Mike O'Donnell; John Kuriyan; P M Burgers; Jerard Hurwitz
The influence of the proliferating cell nuclear antigen-interacting domain of p21(CIP1) on DNA synthesis catalyzed by the human and Saccharomyces cerevisiae polymerase delta holoenzymes.
The Journal of biological chemistry 1997;272(4):2373-81.
1997: John Kuriyan; David Cowburn
Modular peptide recognition domains in eukaryotic signaling.
Annual review of biophysics and biomolecular structure 1997;26():259-88.
1996: Jacqueline M Gulbis; Zvi Kelman; Jerard Hurwitz; Mike O'Donnell; John Kuriyan
Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA.
Cell 1996;87(2):297-306.
1996: Uwe Vinkemeier; Steven Cohen; Ismail Moarefi; Brian T Chait; John Kuriyan; James E Darnell
DNA binding of in vitro activated Stat1 alpha, Stat1 beta and truncated Stat1: interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites.
The EMBO journal 1996;15(20):5616-26.
1996: C H Lee; K Saksela; U A Mirza; Brian T Chait; John Kuriyan
Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain.
Cell 1996;85(6):931-42.
1996: J Goldberg; Angus Nairn; John Kuriyan
Structural basis for the autoinhibition of calcium/calmodulin-dependent protein kinase I.
Cell 1996;84(6):875-87.
1995: C H Lee; B Leung; M A Lemmon; J Zheng; David Cowburn; John Kuriyan; K Saksela
A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein.
The EMBO journal 1995;14(20):5006-15.
1995: D S Wilson; B Guenther; Claude Desplan; John Kuriyan
High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA.
Cell 1995;82(5):709-19.
1995: J Goldberg; H B Huang; Y G Kwon; Paul Greengard; Angus Nairn; John Kuriyan
Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1.
Nature 1995;376(6543):745-53.
1995: X Wu; B Knudsen; Stephan M Feller; J Zheng; Andrej Sali; David Cowburn; Hidesaburo Hanafusa; John Kuriyan
Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk.
Structure (London, England : 1993) 1995;3(2):215-26.
1995: John Kuriyan; D Thanos
Structure of the NF-kappa B transcription factor: a holistic interaction with DNA.
Structure (London, England : 1993) 1995;3(2):135-41.
1994: T S Krishna; X P Kong; S Gary; P M Burgers; John Kuriyan
Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA.
Cell 1994;79(7):1233-43.
1994: T S Krishna; David Fenyö; X P Kong; S Gary; Brian T Chait; P Burgers; John Kuriyan
Crystallization of proliferating cell nuclear antigen (PCNA) from Saccharomyces cerevisiae.
Journal of molecular biology 1994;241(2):265-8.
1994: C H Lee; D Kominos; S Jacques; Benjamin L Margolis; J Schlessinger; S E Shoelson; John Kuriyan
Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
Structure (London, England : 1993) 1994;2(5):423-38.
1994: John Kuriyan
First view of a tyrosine phosphatase structure.
Structure (London, England : 1993) 1994;2(4):327-8.
1994: G Waksman; T S Krishna; C H Williams; John Kuriyan
Crystal structure of Escherichia coli thioredoxin reductase refined at 2 A resolution. Implications for a large conformational change during catalysis.
Journal of molecular biology 1994;236(3):800-16.
1993: John Kuriyan; Mike O'Donnell
Sliding clamps of DNA polymerases.
Journal of molecular biology 1993;234(4):915-25.
1993: J L Martin; James C A Bardwell; John Kuriyan
Crystal structure of the DsbA protein required for disulphide bond formation in vivo.
Nature 1993;365(6445):464-8.
1993: J L Martin; G Waksman; James C A Bardwell; Jonathan R. Beckwith; John Kuriyan
Crystallization of DsbA, an Escherichia coli protein required for disulphide bond formation in vivo.
Journal of molecular biology 1993;230(3):1097-100.
1993: G Waksman; S E Shoelson; N Pant; David Cowburn; John Kuriyan
Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms.
Cell 1993;72(5):779-90.
1992: John Kuriyan; S K Burley
Transcription factors. DNA recognition, warts and all.
Nature 1992;359(6395):476.
1992: Mike O'Donnell; John Kuriyan; X P Kong; P Todd Stukenberg; R Onrust
The sliding clamp of DNA polymerase III holoenzyme encircles DNA.
Molecular biology of the cell 1992;3(9):953-7.
1992: X P Kong; R Onrust; Mike O'Donnell; John Kuriyan
Three-dimensional structure of the beta subunit of E. coli DNA polymerase III holoenzyme: a sliding DNA clamp.
Cell 1992;69(3):425-37.
1991: G B Henderson; N J Murgolo; John Kuriyan; K Osapay; D Kominos; A Berry; Nigel Scrutton; N W Hinchliffe; R N Perham; Anthony Cerami
Engineering the substrate specificity of glutathione reductase toward that of trypanothione reduction.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8769-73.
1991: John Kuriyan; X P Kong; T S Krishna; R M Sweet; N J Murgolo; H Field; Anthony Cerami; G B Henderson
X-ray structure of trypanothione reductase from Crithidia fasciculata at 2.4-A resolution.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8764-8.
1991: John Kuriyan; T S Krishna; L Wong; B Guenther; A Pahler; C H Williams; P Model
Convergent evolution of similar function in two structurally divergent enzymes.
Nature 1991;352(6331):172-4.
1991: John Kuriyan; W I Weis
Rigid protein motion as a model for crystallographic temperature factors.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(7):2773-7.
1991: John Kuriyan; K Osapay; S K Burley; A T Brünger; W A Hendrickson; M Karplus
Exploration of disorder in protein structures by X-ray restrained molecular dynamics.
Proteins 1991;10(4):340-58.
1990: John Kuriyan; L Wong; B D Guenther; N J Murgolo; Anthony Cerami; G B Henderson
Preliminary crystallographic analysis of trypanothione reductase from Crithidia fasciculata.
Journal of molecular biology 1990;215(3):335-7.
1990: K Kuczera; John Kuriyan; M Karplus
Temperature dependence of the structure and dynamics of myoglobin. A simulation approach.
Journal of molecular biology 1990;213(2):351-73.
1989: John Kuriyan; L Wong; Marjorie Russel; P Model
Crystallization and preliminary x-ray characterization of thioredoxin reductase from Escherichia coli.
The Journal of biological chemistry 1989;264(22):12752-3.
1989: John Kuriyan; A T Brünger; M Karplus; W A Hendrickson
X-ray refinement of protein structures by simulated annealing: test of the method on myohemerythrin.
Acta crystallographica. Section A, Foundations of crystallography 1989;45 ( Pt 6)():396-409.
1987: H Frauenfelder; H Hartmann; M Karplus; Irwin D Kuntz; John Kuriyan; F Parak; G A Petsko; D Ringe; R F Tilton; M L Connolly
Thermal expansion of a protein.
Biochemistry 1987;26(1):254-61.
1987: M Karplus; A T Brünger; R Elber; John Kuriyan
Molecular dynamics: applications to proteins.
Cold Spring Harbor symposia on quantitative biology 1987;52():381-90.
1987: John Kuriyan; M Karplus; Gregory A Petsko
Estimation of uncertainties in X-ray refinement results by use of perturbed structures.
Proteins 1987;2(1):1-12.
1986: John Kuriyan; S Wilz; M Karplus; G A Petsko
X-ray structure and refinement of carbon-monoxy (Fe II)-myoglobin at 1.5 A resolution.
Journal of molecular biology 1986;192(1):133-54.
1986: John Kuriyan; G A Petsko; R M Levy; M Karplus
Effect of anisotropy and anharmonicity on protein crystallographic refinement. An evaluation by molecular dynamics.
Journal of molecular biology 1986;190(2):227-54.