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Mineo Kurokawa

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Naoko Watanabe-Okochi; Yutaka Yatomi; Hiromitsu Yokota; Akihide Yoshimi; Toshiyuki Ikeda; Toshio Kitamura; Jiro Kitaura; Keiki Kumano; Akiko Masuda; Tomohiko Sato; Yumiko Satoh; Akihito Shinohara; Koki Takahashi; Kazuki Taoka; Takako Tsuruta; Mineo Kurokawa
The shortest isoform of C/EBPβ, liver inhibitory protein (LIP), collaborates with Evi1 to induce AML in a mouse BMT model.
Sho Hangai; Akira Honda; Motoshi Ichikawa; Yasuhiko Kamikubo; Masahiro Nakagawa; Fumihiko Nakamura; Shunya Arai; Mineo Kurokawa
Erythroleukemia showing early erythroid and cytogenetic responses to azacitidine therapy.
Akihito Shinohara; Yumiko Yoshiki; Akira Hangaishi; Yosuke Masamoto; Yasuhito Nannya; Mineo Kurokawa
Moxifloxacin is more effective than tosufloxacin in reducing chemotherapy-induced febrile neutropneia in patients with hematological malignancies.

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2013: Naoko Watanabe-Okochi; Yutaka Yatomi; Hiromitsu Yokota; Akihide Yoshimi; Toshiyuki Ikeda; Toshio Kitamura; Jiro Kitaura; Keiki Kumano; Akiko Masuda; Tomohiko Sato; Yumiko Satoh; Akihito Shinohara; Koki Takahashi; Kazuki Taoka; Takako Tsuruta; Mineo Kurokawa
The shortest isoform of C/EBPβ, liver inhibitory protein (LIP), collaborates with Evi1 to induce AML in a mouse BMT model.
Blood 2013;121(20):4142-55.
2013: Sho Hangai; Akira Honda; Motoshi Ichikawa; Yasuhiko Kamikubo; Masahiro Nakagawa; Fumihiko Nakamura; Shunya Arai; Mineo Kurokawa
Erythroleukemia showing early erythroid and cytogenetic responses to azacitidine therapy.
Annals of hematology 2013;92(5):707-9.
2013: Akihito Shinohara; Yumiko Yoshiki; Akira Hangaishi; Yosuke Masamoto; Yasuhito Nannya; Mineo Kurokawa
Moxifloxacin is more effective than tosufloxacin in reducing chemotherapy-induced febrile neutropneia in patients with hematological malignancies.
Leukemia & lymphoma 2013;54(4):794-8.
2013: Ken Morita; Yasuhito Nannya; Tetsuichi Yoshizato; Mineo Kurokawa
Simple but powerful prognostic scoring model for MALT lymphoma: a retrospective study.
Annals of hematology 2013;92(3):421-3.
2013: Masaki Ishii; Koji Izutsu; Mineo Kurokawa; Yumiko Ohike; Masahiro Akishita; Masato Eto; Akira Hangaishi; Mitsutaka Yakabe; Yasuhiro Yamaguchi; Yasuyoshi Ouchi
Intravascular large B-cell lymphoma with symptoms resembling progressive dementia: a clinical case report.
Journal of the American Geriatrics Society 2013;61(2):303-4.
2013: Masahiro Uni; Akihide Yoshimi; Masashi Fukayama; Daichi Maeda; Hiroaki Maki; Fumihiko Nakamura; Kumi Nakazaki; Mineo Kurokawa
Successful treatment with recombinant thrombomodulin for B-cell lymphoma-associated hemophagocytic syndrome complicated by disseminated intravascular coagulation.
International journal of clinical and experimental pathology 2013;6(6):1190-4.
2013: Takashi Kobayashi; Motoshi Ichikawa; Yasuhiko Kamikubo; Mineo Kurokawa
Acute myeloid leukemia with cryptic CBFB-MYH11 type D.
International journal of clinical and experimental pathology 2013;6(1):110-2.
2012: Yasuhito Nannya; Mineo Kurokawa
[Acute myeloid leukemia].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 8():496-500.
2012: Sho Hangai; Motoshi Ichikawa; Kazuhiko Koike; Fumihiko Nakamura; Hirotsugu Watabe; Atsuo Yamada; Mineo Kurokawa
Usefulness of double-balloon enteroscopy for evaluation of duodenal follicular lymphoma.
Annals of hematology 2012;91(11):1819-20.
2012: Junji Koya; Yasuhito Nannya; Mineo Kurokawa
Evaluation of procalcitonin with liquid-phase binding assay in hematological malignancy.
Clinica chimica acta; international journal of clinical chemistry 2012;413(19-20):1633-6.
2012: J Koya; M Ichikawa; Yasuhito Nannya; Mineo Kurokawa
The clinical role of procalcitonin in hematopoietic SCT.
Bone marrow transplantation 2012;47(10):1326-31.
2012: Yuki Kagoya; Yasuhito Nannya; Mineo Kurokawa
Thalidomide maintenance therapy for patients with multiple myeloma: meta-analysis.
Leukemia research 2012;36(8):1016-21.
2012: Keisuke Kataoka; Mineo Kurokawa
Ecotropic viral integration site 1, stem cell self-renewal and leukemogenesis.
Cancer science 2012;103(8):1371-7.
2012: Motoshi Ichikawa; Mineo Kurokawa
[Bone marrow failure syndrome (idiopathic hematopoietic disorders): progress in diagnosis and treatment. Topics: III. Diagnosis and treatments; 3. Myelodysplastic syndrome].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2012;101(7):1945-52.
2012: Masashi Miyauchi; Yasuhito Nannya; Yutaka Takazawa; Akihide Yoshimi; Masashi Fukayama; Motoshi Ichikawa; Mineo Kurokawa
Efficacy of pleural biopsy for diagnosis of pleural effusion due to chronic GVHD after hematopoietic stem cell transplantation.
International journal of hematology 2012;96(1):146-8.
2012: Ken Morita; Fumihiko Nakamura; Yasuhito Nannya; Motoshi Ichikawa; Yasuhiko Kamikubo; Mineo Kurokawa
Lymphoma with specific affinity to endocrine organs.
Annals of hematology 2012;91(7):1149-50.
2012: Keiki Kumano; Hiroyuki Aburatani; Shunya Arai; Koji Eto; Masataka Hosoi; Yasuhiko Kamikubo; Genta Nagae; Hiromitsu Nakauchi; Kumi Nakazaki; Makoto Otsu; Naoya Takayama; Kazuki Taoka; Koki Ueda; Mineo Kurokawa
Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples.
Blood 2012;119(26):6234-42.
2012: Ken Morita; Fumihiko Nakamura; Yasuhito Nannya; Go Yamamoto; Motoshi Ichikawa; Yasuhiko Kamikubo; Masashi Miyauchi; Naoaki Mizuno; Mineo Kurokawa
Pituitary lymphoma developing within pituitary adenoma.
International journal of hematology 2012;95(6):721-4.
2012: Junji Koya; Motoshi Ichikawa; Atsushi Iwata; Yu Nagashima; Fumihiko Nakamura; Shoji Tsuji; Mineo Kurokawa
Fludarabine may overcome resistance to rituximab in IgM-related neuropathy.
Journal of the neurological sciences 2012;315(1-2):150-2.
2012: Fumihiko Nakamura; Mineo Kurokawa
[Genetic and cytogenetic abnormalities in leukemia].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 2():103-7.
2012: Mayumi Yoshimi; James C Mulloy; Masahiro Nakagawa; Naoki Shirafuji; Tsuyoshi Takahashi; Takashi Asai; Susumu Goyama; Motoshi Ichikawa; Yoichi Imai; Masahito Kawazu; Andrew S Kraft; Keiki Kumano; Mineo Kurokawa
Multiple phosphorylation sites are important for RUNX1 activity in early hematopoiesis and T-cell differentiation.
European journal of immunology 2012;42(4):1044-50.
2012: Yuki Kagoya; Yasuhito Nannya; Sachiko Seo; Mineo Kurokawa
Hyperlipidemia after allogeneic stem cell transplantation: prevalence, risk factors, and impact on prognosis.
Clinical transplantation 2012;26(2):E168-75.
2012: Yumiko Yoshiki; Masashi Fukayama; Junichi Ishida; Ryozo Nagai; Yasuhito Nannya; Yutaka Takazawa; Go Yamamoto; Mineo Kurokawa
AL amyloidosis with severe gastrointestinal invasion and acute obstructive suppurative cholangitis.
Annals of hematology 2012;91(3):467-8.
2012: Kazuki Taoka; Fumihiko Nakamura; Susumu Goyama; Akira Hangaishi; Masataka Hosoi; Yoichi Imai; Keiki Kumano; Mineo Kurokawa
The effect of iron overload and chelation on erythroid differentiation.
International journal of hematology 2012;95(2):149-59.
2012: Sho Yamazaki; Motoshi Ichikawa; Masahiro Nakagawa; Fumihiko Nakamura; Yasuhito Nannya; Mineo Kurokawa
Early-onset therapy-related myelodysplastic syndrome originating from prolonged myelosuppression after fludarabine-based therapy.
Internal medicine (Tokyo, Japan) 2012;51(24):3427-30.
2012: Takashi Toya; Motoshi Ichikawa; Yasuhito Nannya; Kensuke Narukawa; Mineo Kurokawa
A comparative analysis of meropenem and doripenem in febrile patients with hematologic malignancies: a single-center retrospective study.
Japanese journal of infectious diseases 2012;65(3):228-32.
2012: Kumi Nakazaki; Yasuhito Nannya; Akira Hangaishi; Masataka Hosoi; Motoshi Ichikawa; Mineo Kurokawa
Comparison between pulsed high-dose dexamethasone and daily corticosteroid therapy for adult primary immune thrombocytopenia: a retrospective study.
Internal medicine (Tokyo, Japan) 2012;51(8):859-63.
2012: Yosei Fujioka; Mineo Kurokawa
Follicular lymphoma presenting with massive splenomegaly.
International journal of hematology 2012;95(1):3-4.
2011: Keisuke Kataoka; Hiroshi Kobayashi; Naoto Kubota; Katsuyoshi Kumagai; Keiki Kumano; Shunya Arai; Susumu Goyama; Yoichi Imai; Takashi Kadowaki; Masahiro Nakagawa; Tomohiko Sato; Munetake Shimabe; Takako Tsuruta; Akihide Yoshimi; Mineo Kurokawa
Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity.
The Journal of experimental medicine 2011;208(12):2403-16.
2011: Yuki Kagoya; Masashi Fukayama; Yasuhito Nannya; Satoshi Ota; Aya Shinozaki; Tsuyoshi Takahashi; Mineo Kurokawa
Hyperbilirubinemia after hematopoietic stem cell transplantation: comparison of clinical and pathologic findings in 41 autopsied cases.
Clinical transplantation 2011;25(5):E552-7.
2011: Nahoko Nishimoto; Tsuyoshi Takahashi; Masahiro Nakagawa; Shunya Arai; Susumu Goyama; Motoshi Ichikawa; Yoichi Imai; Yasuhiko Kamikubo; Keiki Kumano; Mineo Kurokawa
Loss of AML1/Runx1 accelerates the development of MLL-ENL leukemia through down-regulation of p19ARF.
Blood 2011;118(9):2541-50.
2011: Mizuki Ogura; Minoru Tanaka; Tomoki Todo; Motoshi Ichikawa; Fumihiko Nakamura; Yasuhito Nannya; Mineo Kurokawa
Temozolomide may induce therapy-related acute lymphoblastic leukaemia.
British journal of haematology 2011;154(5):663-5.
2011: Akihide Yoshimi; Mineo Kurokawa
Evi1 forms a bridge between the epigenetic machinery and signaling pathways.
Oncotarget 2011;2(7):575-86.
2011: Shunya Arai; Susumu Goyama; Motoshi Ichikawa; Yoichi Imai; Masahiro Nakagawa; Munetake Shimabe; Akihide Yoshimi; Mineo Kurokawa
Evi-1 is a transcriptional target of mixed-lineage leukemia oncoproteins in hematopoietic stem cells.
Blood 2011;117(23):6304-14.
2011: Motohiro Kato; Yukio Kobayashi; Mineo Kurokawa; Hiraku Mori; Shigeo Mori; Hitoshi Nakagama; Tatsutoshi Nakahata; Kumi Nakazaki; Akira Niwa; Junko Nomoto; Miki Akatsuka; Yositaka Asakura; Yuyan Chen; Shigeru Chiba; Yasuhide Hayashi; Takashi Igarashi; Yuichi Ishikawa; Itaru Kato; Koji Okamoto; Masashi Sanada; Yasuharu Sato; Kengo Takeuchi; Junko Takita; Kensei Tobinai; Tadashi Yoshino; Seishi Ogawa
[Frequent inactivation of A20 through gene mutation in B-cell lymphomas].
[Rinshō ketsueki] The Japanese journal of clinical hematology 2011;52(6):313-9.
2011: Yasuhito Nannya; Keisuke Kataoka; Akira Hangaishi; Yoichi Imai; Tsuyoshi Takahashi; Mineo Kurokawa
The negative impact of female donor/male recipient combination in allogeneic hematopoietic stem cell transplantation depends on disease risk.
Transplant international : official journal of the European Society for Organ Transplantation 2011;24(5):469-76.
2011: Naoki Kobayashi; Kohjiro Ueki; Yukiko Okazaki; Aya Iwane; Naoto Kubota; Miho Ohsugi; Motoharu Awazawa; Masatoshi Kobayashi; Takayoshi Sasako; K Kaneko; Miho Suzuki; Yoshitaka Nishikawa; Kazuo Hara; Kotaro Yoshimura; Isao Koshima; Susumu Goyama; Koji Murakami; Junko Sasaki; Ryozo Nagai; Mineo Kurokawa; Takehiko Sasaki; Takashi Kadowaki
Blockade of class IB phosphoinositide-3 kinase ameliorates obesity-induced inflammation and insulin resistance.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(14):5753-8.
2011: Katsuyoshi Kumagai; Naoto Kubota; Toshiki I Saito; Takayoshi Sasako; Rumi Takizawa; Katsuko Sudo; Mineo Kurokawa; Takashi Kadowaki
Generation of transgenic mice on an NOD/SCID background using the conventional microinjection technique.
Biology of reproduction 2011;84(4):682-8.
2011: Akihide Yoshimi; Susumu Goyama; Naoko Watanabe-Okochi; Yumiko Yoshiki; Yasuhito Nannya; Eriko Nitta; Shunya Arai; Tomohiko Sato; Munetake Shimabe; Masahiro Nakagawa; Yoichi Imai; Toshio Kitamura; Mineo Kurokawa
Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins.
Blood 2011;117(13):3617-28.
2011: Mineo Kurokawa
[Molecular pathogenesis and treatment of leukemia].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2011;100(3):796-800.
2011: Tetsuichi Yoshizato; Yasuhito Nannya; Yumiko Yoshiki; Fumihiko Nakamura; Yoichi Imai; Motoshi Ichikawa; Mineo Kurokawa
Nilotinib-induced hypothyroidism in a patient with chronic myeloid leukemia.
International journal of hematology 2011;93(3):400-2.
2011: J Koya; Yasuhito Nannya; T Yoshizato; Kenichiro Ono; S Seo; Mina Nakagawa; M Ichikawa; Mineo Kurokawa
Disseminated tuberculosis following unrelated cord blood transplantation for refractory peripheral T-cell lymphoma: Clinical role of serum procalcitonin levels.
The Journal of infection 2011;62(3):237-40.
2011: Yuki Kagoya; Keisuke Kataoka; Yasuhito Nannya; Mineo Kurokawa
Pretransplant predictors and posttransplant sequels of acute kidney injury after allogeneic stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2011;17(3):394-400.
2011: Akihide Yoshimi; Mineo Kurokawa
Key roles of histone methyltransferase and demethylase in leukemogenesis.
Journal of cellular biochemistry 2011;112(2):415-24.
2011: Mamiko Sakata-Yanagimoto; Toru Sakai; Yasuyuki Miyake; Toshiki I Saito; Haruhiko Maruyama; Yasuyuki Morishita; Etsuko Nakagami-Yamaguchi; Keiki Kumano; Hideo Yagita; Masashi Fukayama; Seishi Ogawa; Mineo Kurokawa; Koji Yasutomo; Shigeru Chiba
Notch2 signaling is required for proper mast cell distribution and mucosal immunity in the intestine.
Blood 2011;117(1):128-34.
2011: Yumiko Yoshiki; Satoshi Ota; Tsuyoshi Takahashi; Takashi Asai; Akira Hangaishi; Motoshi Ichikawa; Yoichi Imai; Mineo Kurokawa
A case of myeloid sarcoma with correlation to JAK2V617F mutation, complicated by myelofibrosis and secondary acute myeloid leukemia.
Internal medicine (Tokyo, Japan) 2011;50(21):2649-52.
2011: Hiroshi Kobayashi; Motoshi Ichikawa; Akira Hangaishi; Yoichi Imai; Mineo Kurokawa
Concurrent development of "Burkitt-like" lymphoma and BCL-2-rearranged low-grade B cell lymphoma sharing the same germinal center origin.
International journal of hematology 2011;93(1):112-7.
2010: Sumimasa Nagai; Tsuyoshi Takahashi; Mineo Kurokawa
The impact of molecularly targeted therapies upon the understanding of leukemogenesis and the role of hematopoietic stem cell transplantation in acute promyelocytic leukemia.
Current stem cell research & therapy 2010;5(4):372-8.
2010: Masataka Hosoi; Yasuhito Nannya; Takashi Sasaki; Hiroshi I Suzuki; Koki Ueda; Takeshi Tsujino; Hiroyuki Isayama; Tsuyoshi Takahashi; Kazuhiko Koike; Mineo Kurokawa
Biliary cast syndrome and benign biliary stricture as complications of allogeneic hematopoietic stem cell transplantation.
Annals of hematology 2010;89(12):1287-9.
2010: Kazumitsu Ueda; T Watadani; Eriko Maeda; S Ota; Kazunori Kataoka; S Seo; K Kumano; Akira Hangaishi; Tokiharu Takahashi; Yasuharu Imai; Kuni Ohtomo; Masashi Fukayama; Yasuhito Nannya; Mineo Kurokawa
Outcome and treatment of late-onset noninfectious pulmonary complications after allogeneic haematopoietic SCT.
Bone marrow transplantation 2010;45(12):1719-27.
2010: Motoshi Ichikawa; Akira Hangaishi; Yasuhito Nannya; Mineo Kurokawa
Postremission gemtuzumab ozogamicin for elderly patients with acute myelogenous leukemia with favorable characteristics and comorbid conditions.
International journal of hematology 2010;92(4):673-4.
2010: Masataka Hosoi; Motoshi Ichikawa; Yoichi Imai; Mineo Kurokawa
A case of anaplastic large cell lymphoma, ALK positive, primary presented in the skin and relapsed with systemic involvement and leukocytosis after years of follow-up period.
International journal of hematology 2010;92(4):667-8.
2010: K Kataoka; Yasuhito Nannya; H Iwata; S Seo; K Kumano; Tokiharu Takahashi; Ryozo Nagai; Mineo Kurokawa
Plasma brain natriuretic peptide is associated with hepatic veno-occlusive disease and early mortality after allogeneic hematopoietic stem cell transplantation.
Bone marrow transplantation 2010;45(11):1631-7.
2010: Hiroki Asano; Yoichi Imai; Satoshi Ota; Go Yamamoto; Tsuyoshi Takahashi; Masashi Fukayama; Mineo Kurokawa
CD30-positive anaplastic variant diffuse large B cell lymphoma: a rare case presented with cutaneous involvement.
International journal of hematology 2010;92(3):550-2.
2010: Kumi Nakazaki; Akira Hangaishi; Fumihiko Nakamura; Masataka Hosoi; Yoichi Imai; Tsuyoshi Takahashi; Yasuhito Nannya; Mineo Kurokawa
IgG-associated immune thrombocytopenia in Waldenström macroglobulinemia.
International journal of hematology 2010;92(2):360-3.
2010: Koki Ueda; Motoshi Ichikawa; Miwako Takahashi; Toshimitsu Momose; Kuni Ohtomo; Mineo Kurokawa
FDG-PET is effective in the detection of granulocytic sarcoma in patients with myeloid malignancy.
Leukemia research 2010;34(9):1239-41.
2010: Tomomi Hashidate; Naoka Murakami; Masahiro Nakagawa; Motoshi Ichikawa; Mineo Kurokawa; Takao Shimizu; Motonao Nakamura
AML1 enhances the expression of leukotriene B4 type-1 receptor in leukocytes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(9):3500-10.
2010: Keisuke Kataoka; Sachiko Seo; Yasuhiko Sugawara; Satoshi Ota; Yoichi Imai; Tsuyoshi Takahashi; Masashi Fukayama; Norihiro Kokudo; Mineo Kurokawa
Post-transplant lymphoproliferative disorder after adult-to-adult living donor liver transplant: case series and review of literature.
Leukemia & lymphoma 2010;51(8):1494-501.
2010: Nahoko Nishimoto; Yoichi Imai; K Ueda; Masahiro Nakagawa; Akihito Shinohara; Motoshi Ichikawa; Yasuhito Nannya; Mineo Kurokawa
T cell acute lymphoblastic leukemia arising from familial platelet disorder.
International journal of hematology 2010;92(1):194-7.
2010: Hiroki Asano; Go Yamamoto; Masataka Hosoi; Tsuyoshi Takahashi; Akira Hangaishi; Mineo Kurokawa
Complete molecular remission in refractory acute myeloid leukemia with MLL/AF9 treated with gemtuzumab ozogamicin.
Leukemia research 2010;34(7):e152-3.
2010: Sumimasa Nagai; Yasuhito Nannya; Tsuyoshi Takahashi; Mineo Kurokawa
Jumping translocation involving 1q21 during long-term complete remission of acute myeloid leukemia.
Annals of hematology 2010;89(7):741-2.
2010: Susumu Goyama; Mineo Kurokawa
Evi-1 as a critical regulator of leukemic cells.
International journal of hematology 2010;91(5):753-7.
2010: Yoichi Imai; Motomu Shimaoka; Mineo Kurokawa
Essential roles of VLA-4 in the hematopoietic system.
International journal of hematology 2010;91(4):569-75.
2010: Fumio Nakahara; Mamiko Sakata-Yanagimoto; Yukiko Komeno; Naoko Kato; Tomoyuki Uchida; Kyoko Haraguchi; Keiki Kumano; Yuka Harada; Hironori Harada; Jiro Kitaura; Seishi Ogawa; Mineo Kurokawa; Toshio Kitamura; Shigeru Chiba
Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia.
Blood 2010;115(14):2872-81.
2010: K Kataoka; S Seo; S Ota; Tokiharu Takahashi; Mineo Kurokawa
Positron emission tomography in the diagnosis and therapeutic monitoring of post-transplant lymphoproliferative disorder after cord blood transplantation.
Bone marrow transplantation 2010;45(3):610-2.
2010: K Kataoka; Yasuhito Nannya; K Ueda; K Kumano; Tokiharu Takahashi; Mineo Kurokawa
Differential prognostic impact of pretransplant comorbidity on transplant outcomes by disease status and time from transplant: a single Japanese transplant centre study.
Bone marrow transplantation 2010;45(3):513-20.
2010: Yukako Koike; Koji Miyazaki; Masaaki Higashihara; Emiko Kimura; Masahiro Jona; Kinya Uchihashi; Akiko Masuda; Koji Kandabashi; Mineo Kurokawa; Yutaka Yatomi
Clinical significance of detection of immature platelets: comparison between percentage of reticulated platelets as detected by flow cytometry and immature platelet fraction as detected by automated measurement.
European journal of haematology 2010;84(2):183-4.
2010: Keiki Kumano; Mineo Kurokawa
The role of Runx1/AML1 and Evi-1 in the regulation of hematopoietic stem cells.
Journal of cellular physiology 2010;222(2):282-5.
2010: Akira Hangaishi; Mineo Kurokawa
Blimp-1 is a tumor suppressor gene in lymphoid malignancies.
International journal of hematology 2010;91(1):46-53.
2010: Susumu Goyama; Eriko Nitta; T Yoshino; Shinichi Kako; N Watanabe-Okochi; Munetake Shimabe; Yoichi Imai; Koki Takahashi; Mineo Kurokawa
EVI-1 interacts with histone methyltransferases SUV39H1 and G9a for transcriptional repression and bone marrow immortalization.
Leukemia 2010;24(1):81-8.
2010: Yosuke Masamoto; Sachiko Seo; Masaaki Akahane; Yoichi Imai; Mineo Kurokawa
A case report of non-traumatic renal artery pseudoaneurysm due to chemotherapy for diffuse large B-cell lymphoma.
Annals of hematology 2010;89(1):107-8.
2009: Munetake Shimabe; Susumu Goyama; N Watanabe-Okochi; A Yoshimi; Motoshi Ichikawa; Yoichi Imai; Mineo Kurokawa
Pbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cells.
Oncogene 2009;28(49):4364-74.
2009: Shigeo Masuda; Keiki Kumano; Takahiro Suzuki; Taisuke Tomita; Takeshi Iwatsubo; Hideaki Natsugari; Arinobu Tojo; Makoto Shibutani; Kunitoshi Mitsumori; Yutaka Hanazono; Seishi Ogawa; Mineo Kurokawa; Shigeru Chiba
Dual antitumor mechanisms of Notch signaling inhibitor in a T-cell acute lymphoblastic leukemia xenograft model.
Cancer science 2009;100(12):2444-50.
2009: Akihide Yoshimi; Takashi Asai; Daichi Maeda; Akira Hangaishi; Takashi Sakatani; Tsuyoshi Takahashi; Yoichi Imai; Masashi Fukayama; Mineo Kurokawa
Chronic myelomonocytic leukemia presenting severe uterine hemorrhage due to uterine infiltration of leukemic cells and early-stage endometrial adenocarcinoma.
Archives of gynecology and obstetrics 2009;280(6):1077-8.
2009: Sumimasa Nagai; Tsuyoshi Takahashi; Mineo Kurokawa
Beneficial and adverse effects of molecularly targeted therapies for acute promyelocytic leukemia in central nervous system.
CNS & neurological disorders drug targets 2009;8(5):387-92.
2009: Motoshi Ichikawa; Mineo Kurokawa
[Molecular mechanisms in the development of acute myeloid leukemia].
Nihon rinsho. Japanese journal of clinical medicine 2009;67(10):1889-93.
2009: Sumimasa Nagai; Yasuhito Nannya; Akira Hangaishi; Tsuyoshi Takahashi; Mineo Kurokawa
The race and dose of chemotherapy should be considered for optimizing maintenance therapy for acute promyelocytic leukemia.
Leukemia research 2009;33(10):1427-9.
2009: Tsuyoshi Takahashi; Mineo Kurokawa
Human invariant natural killer T cells: implications for immunotherapy.
International journal of hematology 2009;90(2):137-42.
2009: Masashi Sanada; Takahiro Suzuki; Lee-Yung Shih; Makoto Otsu; Motohiro Kato; Satoshi Yamazaki; Azusa Tamura; Hiroaki Honda; Mamiko Sakata-Yanagimoto; Keiki Kumano; Hideaki Oda; Tetsuya Yamagata; Junko Takita; Noriko Gotoh; Kumi Nakazaki; Norihiko Kawamata; Masafumi Onodera; Masaharu Nobuyoshi; Yasuhide Hayashi; Hiroshi Harada; Mineo Kurokawa; Shigeru Chiba; Hiraku Mori; Keiya Ozawa; Mitsuhiro Omine; Hisamaru Hirai; Hiromitsu Nakauchi; H Phillip Koeffler; Seishi Ogawa
Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.
Nature 2009;460(7257):904-8.
2009: Yasuhisa Yokoyama; Takahiro Suzuki; Mamiko Sakata-Yanagimoto; Keiki Kumano; Katsumi Higashi; Tsuyoshi Takato; Mineo Kurokawa; Seishi Ogawa; Shigeru Chiba
Derivation of functional mature neutrophils from human embryonic stem cells.
Blood 2009;113(26):6584-92.
2009: Motohiro Kato; Masashi Sanada; Itaru Kato; Yasuharu Sato; Junko Takita; Kengo Takeuchi; Akira Niwa; Yuyan Chen; Kumi Nakazaki; Junko Nomoto; Yoshitaka Asakura; Satsuki Muto; Azusa Tamura; Mitsuru Iio; Yoshiki Akatsuka; Yasuhide Hayashi; Hiraku Mori; Takashi Igarashi; Mineo Kurokawa; Shigeru Chiba; Shigeo Mori; Yuichi Ishikawa; Koji Okamoto; Kensei Tobinai; Hitoshi Nakagama; Tatsutoshi Nakahata; Tadashi Yoshino; Yukio Kobayashi; Seishi Ogawa
Frequent inactivation of A20 in B-cell lymphomas.
Nature 2009;459(7247):712-6.
2009: Susumu Goyama; Mineo Kurokawa
Pathogenetic significance of ecotropic viral integration site-1 in hematological malignancies.
Cancer science 2009;100(6):990-5.
2009: Koki Ueda; Yasuhito Nannya; Keiki Kumano; Akira Hangaishi; Tsuyoshi Takahashi; Yoichi Imai; Mineo Kurokawa
Monitoring trough concentration of voriconazole is important to ensure successful antifungal therapy and to avoid hepatic damage in patients with hematological disorders.
International journal of hematology 2009;89(5):592-9.
2009: Sumimasa Nagai; Koji Izutsu; Takuro Watanabe; Mineo Kurokawa
Simultaneous appearance of methotrexate-associated lymphoproliferative disorder and tuberculous meningitis demonstrating the definitive role of immunosuppression.
Annals of hematology 2009;88(6):589-90.
2009: Kyoko Haraguchi; Takahiro Suzuki; Noriko Koyama; Keiki Kumano; Fumio Nakahara; Akihiko Matsumoto; Yasuhisa Yokoyama; Mamiko Sakata-Yanagimoto; Shigeo Masuda; Tsuyoshi Takahashi; Aki Kamijo; Koki Takahashi; Minoko Takanashi; Yoshiki Okuyama; Koji Yasutomo; Seiji Sakano; Hideo Yagita; Mineo Kurokawa; Seishi Ogawa; Shigeru Chiba
Notch activation induces the generation of functional NK cells from human cord blood CD34-positive cells devoid of IL-15.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(10):6168-78.
2009: Suk-young Lee; Keiki Kumano; Kumi Nakazaki; Masashi Sanada; Akihiko Matsumoto; Go Yamamoto; Yasuhito Nannya; Ritsuro Suzuki; Satoshi Ota; Yasunori Ota; Koji Izutsu; Mamiko Sakata-Yanagimoto; Akira Hangaishi; Hideo Yagita; Masashi Fukayama; Masao Seto; Mineo Kurokawa; Seishi Ogawa; Shigeru Chiba
Gain-of-function mutations and copy number increases of Notch2 in diffuse large B-cell lymphoma.
Cancer science 2009;100(5):920-6.
2009: Takayasu Kato; Akira Hangaishi; Motoshi Ichikawa; Toru Motokura; Tsuyoshi Takahashi; Mineo Kurokawa
A new three-way variant t(15;22;17)(q22;q11.2;q21) in acute promyelocytic leukemia.
International journal of hematology 2009;89(2):204-8.
2009: Mayumi Yoshimi; Yasuhito Nannya; Takuro Watanabe; Takashi Asai; Motoshi Ichikawa; Go Yamamoto; Keiki Kumano; Akira Hangaishi; Yoichi Imai; Tsuyoshi Takahashi; Shigeru Chiba; Mineo Kurokawa
Acute eosinophilic pneumonia is a non-infectious lung complication after allogeneic hematopoietic stem cell transplantation.
International journal of hematology 2009;89(2):244-8.
2009: Yosuke Masamoto; Yasuhito Nannya; Syunya Arai; Yukako Koike; Akira Hangaishi; Yutaka Yatomi; Mineo Kurokawa
Evidence for basophilic differentiation of acute promyelocytic leukaemia cells during arsenic trioxide therapy.
British journal of haematology 2009;144(5):798-9.
2009: Keisuke Kataoka; Yasuhito Nannya; Akira Hangaishi; Yoichi Imai; Shigeru Chiba; Tsuyoshi Takahashi; Mineo Kurokawa
Influence of pretransplantation serum ferritin on nonrelapse mortality after myeloablative and nonmyeloablative allogeneic hematopoietic stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2009;15(2):195-204.
2009: Sayaka Shibata; Makoto Sugaya; Yosaku Minatani; Hideki Fujita; Yuichiro Tsunemi; Tomomitsu Miyagaki; Hidehisa Saeki; Kanako Kikuchi; Takashi Asai; Mineo Kurokawa; Kunihiko Tamaki
Folliculotropic mycosis fungoides with severe hepatic failure due to hepatic involvement.
Acta dermato-venereologica 2009;89(4):423-4.
2009: Tomomitsu Miyagaki; Makoto Sugaya; Yosaku Minatani; Hideki Fujita; Akira Hangaishi; Mineo Kurokawa; Yutaka Takazawa; Kunihiko Tamaki
Mycosis fungoides with recurrent Hodgkin's lymphoma and diffuse large B-cell lymphoma.
Acta dermato-venereologica 2009;89(4):421-2.
2008: Keiichi Nakagawa; Yoshinobu Kanda; Hideomi Yamashita; S Nakagawa; Nakashi Sasano; Kuni Ohtomo; Kumi Oshima; K Kumano; N Ban; Y Nannya; Y Minamitani; Mineo Kurokawa; Shigeru Chiba
Ovarian shielding allows ovarian recovery and normal birth in female hematopoietic SCT recipients undergoing TBI.
Bone marrow transplantation 2008;42(10):697-9.
2008: Kumi Oshima; Yoshinobu Kanda; Shinichi Kako; Yuki Asano-Mori; Takuro Watanabe; Toru Motokura; Shigeru Chiba; Kimiyasu Shiraki; Mineo Kurokawa
Case report: persistent cytomegalovirus (CMV) infection after haploidentical hematopoietic stem cell transplantation using in vivo alemtuzumab: emergence of resistant CMV due to mutations in the UL97 and UL54 genes.
Journal of medical virology 2008;80(10):1769-75.
2008: Akiko Masuda; Kazuhiro Nakamura; Koji Izutsu; Koji Igarashi; Ryunosuke Ohkawa; Masahiro Jona; Katsumi Higashi; Hiromitsu Yokota; Shinichi Okudaira; Tatsuya Kishimoto; Takuro Watanabe; Yukako Koike; Hitoshi Ikeda; Yasushi Kozai; Mineo Kurokawa; Junken Aoki; Yutaka Yatomi
Serum autotaxin measurement in haematological malignancies: a promising marker for follicular lymphoma.
British journal of haematology 2008;143(1):60-70.
2008: Akihide Yoshimi; Takashi Asai; Akira Hangaishi; Tsuyoshi Takahashi; Shigeru Chiba; Mineo Kurokawa
Hemorrhagic cystitis in a patient receiving gemtuzumab ozogamicin for relapsed acute promyelocytic leukemia after cord blood transplantation.
Annals of hematology 2008;87(10):851-2.
2008: Yasuhito Nannya; Hiromitsu Yokota; Yumiko Sato; Go Yamamoto; Takashi Asai; Motoshi Ichikawa; Takuro Watanabe; Keiki Kumano; Akira Hangaishi; Tsuyoshi Takahashi; Shigeru Chiba; Yutaka Yatomi; Mineo Kurokawa
Molecular and cytogenetic response of chronic myelogenous leukemia treated with imatinib mesylate: one institutional experience in Japan.
International journal of hematology 2008;88(2):159-64.
2008: Susumu Goyama; Go Yamamoto; Munetake Shimabe; Tomohiko Sato; Motoshi Ichikawa; Seishi Ogawa; Shigeru Chiba; Mineo Kurokawa
Evi-1 is a critical regulator for hematopoietic stem cells and transformed leukemic cells.
Cell stem cell 2008;3(2):207-20.
2008: Akihide Yoshimi; Yasuhito Nannya; Mamiko Sakata-Yanagimoto; Kumi Oshima; Tsuyoshi Takahashi; Yoshinobu Kanda; Toru Motokura; Shigeru Chiba; Mineo Kurokawa
A myeloablative conditioning regimen for patients with impaired cardiac function undergoing allogeneic stem cell transplantation: reduced cyclophosphamide combined with etoposide and total body irradiation.
American journal of hematology 2008;83(8):635-9.
2008: Hi Suzuki; Takahiro Suzuki; Atsuko Kamijo; S Oota; Hiroyuki Sato; Akira Hangaishi; Tokiharu Takahashi; Yoshinobu Kanda; Toru Motokura; Shigeru Chiba; Mineo Kurokawa
Antileukemic immunity associated with antineutrophil antibody production after allogeneic hematopoietic SCT for myeloid/NK-cell precursor acute leukemia.
Bone marrow transplantation 2008;42(4):285-7.
2008: Hiroshi I Suzuki; Koji Izutsu; Takuro Watanabe; Kumi Oshima; Yoshinobu Kanda; Toru Motokura; Shigeru Chiba; Mineo Kurokawa
Late-onset pneumatosis cystoides intestinalis associated with non-infectious pulmonary complications after allogeneic hematopoietic stem cell transplantation.
International journal of hematology 2008;88(1):116-8.
2008: Tomohiko Sato; Susumu Goyama; Eriko Nitta; Masataka Takeshita; Mayumi Yoshimi; Masahiro Nakagawa; Masahito Kawazu; Motoshi Ichikawa; Mineo Kurokawa
Evi-1 promotes para-aortic splanchnopleural hematopoiesis through up-regulation of GATA-2 and repression of TGF-b signaling.
Cancer science 2008;99(7):1407-13.
2008: K Kataoka; G Yamamoto; Yasuhito Nannya; A Yoshimi; S Okada; Takashi Asai; K Kumano; Akira Hangaishi; Tokiharu Takahashi; Shigeru Chiba; Mineo Kurokawa
Successful engraftment following HLA-mismatched cord blood transplantation for patients with anti-HLA Abs.
Bone marrow transplantation 2008;42(2):129-30.
2008: Sumimasa Nagai; Takashi Asai; Takuro Watanabe; Kumi Oshima; Akira Hangaishi; Yoshinobu Kanda; Toru Motokura; Shigeru Chiba; Shigeki Aoki; Kuni Ohtomo; Mineo Kurokawa
Simultaneous appearance of central nervous system relapse and subarachnoid hemorrhage during the treatment for acute promyelocytic leukemia.
Annals of hematology 2008;87(7):593-5.
2008: Mamiko Sakata-Yanagimoto; Etsuko Nakagami-Yamaguchi; Toshiki Saito; Keiki Kumano; Koji Yasutomo; Seishi Ogawa; Mineo Kurokawa; Shigeru Chiba
Coordinated regulation of transcription factors through Notch2 is an important mediator of mast cell fate.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(22):7839-44.
2008: Akihide Yoshimi; Keiki Kumano; Toru Motokura; Yutaka Takazawa; Satoshi Oota; Shigeru Chiba; Tsuyoshi Takahashi; Masashi Fukayama; Mineo Kurokawa
ESHAP therapy effective in a patient with Langerhans cell sarcoma.
International journal of hematology 2008;87(5):532-7.
2008: Hiroshi I Suzuki; Akira Hangaishi; Noriko Hosoya; Takuro Watanabe; Yoshinobu Kanda; Toru Motokura; Shigeru Chiba; Mineo Kurokawa
Herpes simplex encephalitis and subsequent cytomegalovirus encephalitis after chemoradiotherapy for central nervous system lymphoma: a case report and literature review.
International journal of hematology 2008;87(5):538-41.
2008: Masataka Takeshita; M Ichikawa; Eriko Nitta; Susumu Goyama; Takashi Asai; Seishi Ogawa; Shigeru Chiba; Mineo Kurokawa
AML1-Evi-1 specifically transforms hematopoietic stem cells through fusion of the entire Evi-1 sequence to AML1.
Leukemia 2008;22(6):1241-9.
2008: Yuki Asano-Mori; Yoshinobu Kanda; Kumi Oshima; Shinichi Kako; Akihito Shinohara; Hideki Nakasone; Hiroyuki Sato; Takuro Watanabe; Noriko Hosoya; Koji Izutsu; Takashi Asai; Akira Hangaishi; Toru Motokura; Shigeru Chiba; Mineo Kurokawa
Long-term ultra-low-dose acyclovir against varicella-zoster virus reactivation after allogeneic hematopoietic stem cell transplantation.
American journal of hematology 2008;83(6):472-6.
2008: Akihide Yoshimi; Koji Izutsu; Miwako Takahashi; Shinichi Kako; Kumi Oshima; Yoshinobu Kanda; Toru Motokura; Shigeru Chiba; Toshimitsu Momose; Kuni Ohtomo; Mineo Kurokawa
Conventional allogeneic hematopoietic stem cell transplantation for lymphoma may overcome the poor prognosis associated with a positive FDG-PET scan before transplantation.
American journal of hematology 2008;83(6):477-81.
2008: Hiroyuki Ishiura; Masato Morikawa; Masashi Hamada; Takuro Watanabe; Shinichi Kako; Shigeru Chiba; Toru Motokura; Akira Hangaishi; Junji Shibahara; Masaaki Akahane; Jun Goto; Shin Kwak; Mineo Kurokawa; Shoji Tsuji
Lymphomatoid granulomatosis involving central nervous system successfully treated with rituximab alone.
Archives of neurology 2008;65(5):662-5.
2008: Motoshi Ichikawa; Susumu Goyama; Takashi Asai; Masahito Kawazu; Masahiro Nakagawa; Masataka Takeshita; Shigeru Chiba; Seishi Ogawa; Mineo Kurokawa
AML1/Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(7):4402-8.
2008: Yuki Asano-Mori; Yoshinobu Kanda; Kumi Oshima; Shinichi Kako; Akihito Shinohara; Hideki Nakasone; Hiroyuki Sato; Takuro Watanabe; Noriko Hosoya; Koji Izutsu; Takashi Asai; Akira Hangaishi; Toru Motokura; Shigeru Chiba; Mineo Kurokawa
Clinical features of late cytomegalovirus infection after hematopoietic stem cell transplantation.
International journal of hematology 2008;87(3):310-8.
2008: Takahiro Suzuki; Koji Izutsu; Shinichi Kako; Satoshi Ohta; Akira Hangaishi; Yoshinobu Kanda; Toru Motokura; Shigeru Chiba; Mineo Kurokawa
A case of adult Langerhans cell histiocytosis showing successfully regenerated osseous tissue of the skull after chemotherapy.
International journal of hematology 2008;87(3):284-8.
2008: Kumi Oshima; Yoshinobu Kanda; Hideki Nakasone; Shunya Arai; Nahoko Nishimoto; Hiroyuki Sato; Takuro Watanabe; Noriko Hosoya; Koji Izutsu; Takashi Asai; Akira Hangaishi; Toru Motokura; Shigeru Chiba; Mineo Kurokawa
Decreased incidence of acute graft-versus-host disease by continuous infusion of cyclosporine with a higher target blood level.
American journal of hematology 2008;83(3):226-32.
2008: Shinichi Kako; Yoshinobu Kanda; Kumi Oshima; Nahoko Nishimoto; Hiroyuki Sato; Takuro Watanabe; Noriko Hosoya; Toru Motokura; Shigesaburo Miyakoshi; Shuichi Taniguchi; Atsuko Kamijo; Koki Takahashi; Shigeru Chiba; Mineo Kurokawa
Late onset of autoimmune hemolytic anemia and pure red cell aplasia after allogeneic hematopoietic stem cell transplantation using in vivo alemtuzumab.
American journal of hematology 2008;83(3):247-9.
2008: Keiki Kumano; Shigeo Masuda; Masataka Sata; Toshiki Saito; Suk-Young Lee; Mamiko Sakata-Yanagimoto; Taisuke Tomita; Takeshi Iwatsubo; Hideaki Natsugari; Mineo Kurokawa; Seishi Ogawa; Shigeru Chiba
Both Notch1 and Notch2 contribute to the regulation of melanocyte homeostasis.
Pigment cell & melanoma research 2008;21(1):70-8.
2008: Yuki Asano-Mori; Yoshinobu Kanda; Kumi Oshima; Shinichi Kako; Akihito Shinohara; Hideki Nakasone; Makoto Kaneko; Hiroyuki Sato; Takuro Watanabe; Noriko Hosoya; Koji Izutsu; Takashi Asai; Akira Hangaishi; Toru Motokura; Shigeru Chiba; Mineo Kurokawa
False-positive Aspergillus galactomannan antigenaemia after haematopoietic stem cell transplantation.
The Journal of antimicrobial chemotherapy 2008;61(2):411-6.
2007: Shunya Arai; Takashi Asai; Hiroshi Uozaki; Akira Hangaishi; Yoshinobu Kanda; Toru Motokura; Shigeru Chiba; Mineo Kurokawa
Splenic peliosis in a patient with aplastic anemia during danazol therapy.
International journal of hematology 2007;86(4):329-32.
2007: Sumimasa Nagai; Motoshi Ichikawa; Tsuyoshi Takahashi; Hiroyuki Sato; Hiromitsu Yokota; Kumi Oshima; Koji Izutsu; Akira Hangaishi; Yoshinobu Kanda; Toru Motokura; Shigeru Chiba; Yutaka Yatomi; Mineo Kurokawa
The origin of neoplastic mast cells in systemic mastocytosis with AML1/ETO-positive acute myeloid leukemia.
Experimental hematology 2007;35(11):1747-52.
2007: Akira Hangaishi; Mineo Kurokawa
[Drug-induced thrombocytopenia].
Nihon rinsho. Japanese journal of clinical medicine 2007;65 Suppl 8():465-9.
2007: Masahito Kawazu; Go Yamamoto; Mayumi Yoshimi; Kazuki Yamamoto; Takashi Asai; Motoshi Ichikawa; Sachiko Seo; Masahiro Nakagawa; Shigeru Chiba; Mineo Kurokawa; Seishi Ogawa
Expression profiling of immature thymocytes revealed a novel homeobox gene that regulates double-negative thymocyte development.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):5335-45.
2007: Yasuhito Nannya; Kenjiro Taura; Mineo Kurokawa; Shigeru Chiba; Seishi Ogawa
Evaluation of genome-wide power of genetic association studies based on empirical data from the HapMap project.
Human molecular genetics 2007;16(20):2494-505.
2007: Shinichi Kako; Koji Izutsu; Y Ota; Yosaku Minatani; Makoto Sugaya; T Momose; K Ohtomo; Yoshinobu Kanda; Shigeru Chiba; Toru Motokura; Mineo Kurokawa
FDG-PET in T-cell and NK-cell neoplasms.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2007;18(10):1685-90.
2007: Shinichi Kako; Koji Izutsu; Kumi Oshima; Hiroyuki Sato; Yoshinobu Kanda; Toru Motokura; Shigeru Chiba; Mineo Kurokawa
Regression of the tumor after withdrawal of cyclosporine in relapsed extranodal natural killer/T cell lymphoma following allogeneic hematopoietic stem cell transplantation.
American journal of hematology 2007;82(10):937-9.
2007: Takayuki Ishikawa; Kaoru Tohyama; Shinji Nakao; Yataro Yoshida; Masanao Teramura; Toshiko Motoji; Masaaki Takatoku; Mineo Kurokawa; Kinuko Mitani; Takashi Uchiyama; Mitsuhiro Omine
A prospective study of cyclosporine A treatment of patients with low-risk myelodysplastic syndrome: presence of CD55(-)CD59(-) blood cells predicts platelet response.
International journal of hematology 2007;86(2):150-7.
2007: Kumi Oshima; Yoshinobu Kanda; Yuki Asano-Mori; Nahoko Nishimoto; Shunya Arai; Sumimasa Nagai; Hiroyuki Sato; Takuro Watanabe; Noriko Hosoya; Koji Izutsu; Takashi Asai; Akira Hangaishi; Toru Motokura; Shigeru Chiba; Mineo Kurokawa
Presumptive treatment strategy for aspergillosis in allogeneic haematopoietic stem cell transplant recipients.
The Journal of antimicrobial chemotherapy 2007;60(2):350-5.
2007: Go Yamamoto; Yasuhito Nannya; Motohiro Kato; Masashi Sanada; Ross Levine; Norihiko Kawamata; Akira Hangaishi; Mineo Kurokawa; Shigeru Chiba; D Gary Gilliland; H Phillip Koeffler; Seishi Ogawa
Highly sensitive method for genomewide detection of allelic composition in nonpaired, primary tumor specimens by use of affymetrix single-nucleotide-polymorphism genotyping microarrays.
American journal of human genetics 2007;81(1):114-26.
2007: Masashi Sanada; N Uike; Kazuma Ohyashiki; Keiya Ozawa; W Lili; Akira Hangaishi; Yoshinobu Kanda; Shigeru Chiba; Mineo Kurokawa; Mitsuhiro Omine; Kinuko Mitani; Seishi Ogawa
Unbalanced translocation der(1;7)(q10;p10) defines a unique clinicopathological subgroup of myeloid neoplasms.
Leukemia 2007;21(5):992-7.
2007: Shinichi Kako; Yoshinobu Kanda; Tomohiko Sato; Susumu Goyama; Naohiro Noda; Eriko Shoda; Kumi Oshima; Morihiro Inoue; Koji Izutsu; Takuro Watanabe; Toru Motokura; Shigeru Chiba; Masashi Fukayama; Mineo Kurokawa
Early relapse of JAK2 V617F-positive chronic neutrophilic leukemia with central nervous system infiltration after unrelated bone marrow transplantation.
American journal of hematology 2007;82(5):386-90.
2007: Akihiko Matsumoto; Kyoko Haraguchi; Tsuyoshi Takahashi; Takeshi Azuma; Yoshinobu Kanda; Kyoichi Tomita; Mineo Kurokawa; Seishi Ogawa; Koki Takahashi; Shigeru Chiba; Tadaichi Kitamura
Immunotherapy against metastatic renal cell carcinoma with mature dendritic cells.
International journal of urology : official journal of the Japanese Urological Association 2007;14(4):277-83.
2007: Eriko Nitta; Koji Izutsu; T Sato; Y Ota; K Takeuchi; Atsuko Kamijo; K Takahashi; K Oshima; Yoshinobu Kanda; Shigeru Chiba; Toru Motokura; Mineo Kurokawa
A high incidence of late-onset neutropenia following rituximab-containing chemotherapy as a primary treatment of CD20-positive B-cell lymphoma: a single-institution study.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2007;18(2):364-9.
2007: Mineo Kurokawa
[An introduction to diagnosis of malignant lymphoma].
Nihon rinsho. Japanese journal of clinical medicine 2007;65 Suppl 1():335-41.
2007: Akiko M Saito; Shigeru Chiba; Seishi Ogawa; Yoshinobu Kanda; Hisamaru Hirai; Mineo Kurokawa
Long-term sustained mixed chimerism after allogeneic stem cell transplantation in a patient with severe aplastic anemia.
Internal medicine (Tokyo, Japan) 2007;46(23):1923-6.
2006: Uichi Nishiyama; Tetsuya Yoshino; Masako Ozai; Rieko Yoshioka; Motoko Fujisawa; Yuko Ogasawara; Miyuki Kitahori; Eiji Yoshioka; Kazuo Kubo; Yukiko Komeno; Mineo Kurokawa; Seishi Ogawa; Shigeru Chiba; Tatsushi Osawa; Tomoaki Kuwaki; Hisamaru Hirai; Atsushi Miwa
Antineoplastic effect of a single oral dose of the novel Flt3 inhibitor KRN383 on xenografted human leukemic cells harboring Flt3-activating mutations.
Leukemia research 2006;30(12):1541-6.
2006: Masahiro Nakagawa; Motoshi Ichikawa; Keiki Kumano; Susumu Goyama; Masahito Kawazu; Takashi Asai; Seishi Ogawa; Mineo Kurokawa; Shigeru Chiba
AML1/Runx1 rescues Notch1-null mutation-induced deficiency of para-aortic splanchnopleural hematopoiesis.
Blood 2006;108(10):3329-34.
2006: Kumi Oshima; Yoshinobu Kanda; Fumio Nakahara; Eriko Shoda; Takahiro Suzuki; Yoichi Imai; Takuro Watanabe; Takashi Asai; Koji Izutsu; Seishi Ogawa; Toru Motokura; Shigeru Chiba; Mineo Kurokawa
Pharmacokinetics of alemtuzumab after haploidentical HLA-mismatched hematopoietic stem cell transplantation using in vivo alemtuzumab with or without CD52-positive malignancies.
American journal of hematology 2006;81(11):875-9.
2006: Takahiro Suzuki; Yasuhisa Yokoyama; Keiki Kumano; Minoko Takanashi; Shiro Kozuma; Tsuyoshi Takato; Tatsutoshi Nakahata; Mitsuo Nishikawa; Seiji Sakano; Mineo Kurokawa; Seishi Ogawa; Shigeru Chiba
Highly efficient ex vivo expansion of human hematopoietic stem cells using Delta1-Fc chimeric protein.
Stem cells (Dayton, Ohio) 2006;24(11):2456-65.
2006: Kyoko Haraguchi; Tsuyoshi Takahashi; Fumio Nakahara; Akihiko Matsumoto; Mineo Kurokawa; Seishi Ogawa; Hideaki Oda; Hisamaru Hirai; Shigeru Chiba
CD1d expression level in tumor cells is an important determinant for anti-tumor immunity by natural killer T cells.
Leukemia & lymphoma 2006;47(10):2218-23.
2006: Mineo Kurokawa
AML1/Runx1 as a versatile regulator of hematopoiesis: regulation of its function and a role in adult hematopoiesis.
International journal of hematology 2006;84(2):136-42.
2006: Hideomi Yamashita; Koji Izutsu; Naoki Nakamura; Kenshiro Shiraishi; Shigeru Chiba; Mineo Kurokawa; Masao Tago; Hiroshi Igaki; Kuni Ohtomo; Keiichi Nakagawa
Treatment results of chemoradiation therapy for localized aggressive lymphomas: A retrospective 20-year study.
Annals of hematology 2006;85(8):523-9.
2006: Yuki Asano-Mori; Yoshinobu Kanda; Kumi Oshima; Takuro Watanabe; Eriko Shoda; Toru Motokura; Mineo Kurokawa; Shigeru Chiba
Pharmacokinetics of ganciclovir in haematopoietic stem cell transplantation recipients with or without renal impairment.
The Journal of antimicrobial chemotherapy 2006;57(5):1004-7.
2006: Noriko Hosoya; Masashi Sanada; Yasuhito Nannya; Kumi Nakazaki; Lili Wang; Akira Hangaishi; Mineo Kurokawa; Shigeru Chiba; Seishi Ogawa
Genomewide screening of DNA copy number changes in chronic myelogenous leukemia with the use of high-resolution array-based comparative genomic hybridization.
Genes, chromosomes & cancer 2006;45(5):482-94.
2006: Sachiko Seo; Motoshi Ichikawa; Mineo Kurokawa
Structure and function of cas-L and integrin-mediated signaling.
Critical reviews in immunology 2006;26(5):391-406.
2005: Aleksandra Crcareva; Toshiki Saito; Atsushi Kunisato; Keiki Kumano; Takahiro Suzuki; Mamiko Sakata-Yanagimoto; Masahito Kawazu; Aleksandar Stojanovic; Mineo Kurokawa; Seishi Ogawa; Hisamaru Hirai; Shigeru Chiba
Hematopoietic stem cells expanded by fibroblast growth factor-1 are excellent targets for retrovirus-mediated gene delivery.
Experimental hematology 2005;33(12):1459-69.
2005: Yuki Asano-Mori; Kumi Oshima; Mamiko Sakata-Yanagimoto; Masahiro Nakagawa; Koji Kandabashi; Koji Izutsu; Akira Hangaishi; Toru Motokura; Shigeru Chiba; Mineo Kurokawa; Hisamura Hirai; Yoshinobu Kanda
High-grade cytomegalovirus antigenemia after hematopoietic stem cell transplantation.
Bone marrow transplantation 2005;36(9):813-9.
2005: Kumi Oshima; Mamiko Sakata-Yanagimoto; Yuki Asano-Mori; Koji Izutsu; Tsutomu Watanabe; Eriko Shoda; Seishi Ogawa; Toru Motokura; Shigeru Chiba; Mineo Kurokawa; Hisamura Hirai; Yoshinobu Kanda
Cardiac complications after haploidentical HLA-mismatched hematopoietic stem cell transplantation using in vivo alemtuzumab.
Bone marrow transplantation 2005;36(9):821-4.
2005: S-Y Lee; K Kumano; S Masuda; Akira Hangaishi; J Takita; Kumi Nakazaki; Mineo Kurokawa; Y Hayashi; Seishi Ogawa; Shigeru Chiba
Mutations of the Notch1 gene in T-cell acute lymphoblastic leukemia: analysis in adults and children.
Leukemia 2005;19(10):1841-3.
2005: Sachiko Seo; Takashi Asai; Toshiki Saito; Takahiro Suzuki; Yasuyuki Morishita; Tetsuya Nakamoto; Motoshi Ichikawa; Go Yamamoto; Masahito Kawazu; Tetsuya Yamagata; Ryuichi Sakai; Kinuko Mitani; Seishi Ogawa; Mineo Kurokawa; Shigeru Chiba; Hisamaru Hirai
Crk-associated substrate lymphocyte type is required for lymphocyte trafficking and marginal zone B cell maintenance.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(6):3492-501.
2005: Eriko Nitta; Koji Izutsu; Yuko Yamaguchi; Yoichi Imai; Seishi Ogawa; Shigeru Chiba; Mineo Kurokawa; Hisamaru Hirai
Oligomerization of Evi-1 regulated by the PR domain contributes to recruitment of corepressor CtBP.
Oncogene 2005;24(40):6165-73.
2005: Yasuhito Nannya; Masashi Sanada; Kumi Nakazaki; Noriko Hosoya; Lili Wang; Akira Hangaishi; Mineo Kurokawa; Shigeru Chiba; Dione K Bailey; Giulia C Kennedy; Seishi Ogawa
A robust algorithm for copy number detection using high-density oligonucleotide single nucleotide polymorphism genotyping arrays.
Cancer research 2005;65(14):6071-9.
2005: Kyoko Haraguchi; Tsuyoshi Takahashi; Akihiko Matsumoto; Takashi Asai; Yoshinobu Kanda; Mineo Kurokawa; Seishi Ogawa; Hideaki Oda; Masaru Taniguchi; Hisamaru Hirai; Shigeru Chiba
Host-residual invariant NK T cells attenuate graft-versus-host immunity.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(2):1320-8.
2005: Yukiko Komeno; Mineo Kurokawa; Yoichi Imai; Masataka Takeshita; T Matsumura; Kazuo Kubo; T Yoshino; Uichi Nishiyama; Tomoaki Kuwaki; K Kubo; T Osawa; Seishi Ogawa; Shigeru Chiba; A Miwa; Hisamura Hirai
Identification of Ki23819, a highly potent inhibitor of kinase activity of mutant FLT3 receptor tyrosine kinase.
Leukemia 2005;19(6):930-5.
2005: Shigeo Masuda; Keiki Kumano; Kiyoshi Shimizu; Yoichi Imai; Mineo Kurokawa; Seishi Ogawa; Makoto Miyagishi; Kazunari Taira; Hisamaru Hirai; Shigeru Chiba
Notch1 oncoprotein antagonizes TGF-beta/Smad-mediated cell growth suppression via sequestration of coactivator p300.
Cancer science 2005;96(5):274-82.
2005: Masahito Kawazu; Takashi Asai; Motoshi Ichikawa; Go Yamamoto; Toshiki Saito; Susumu Goyama; Kinuko Mitani; Kohei Miyazono; Shigeru Chiba; Seishi Ogawa; Mineo Kurokawa; Hisamaru Hirai
Functional domains of Runx1 are differentially required for CD4 repression, TCRbeta expression, and CD4/8 double-negative to CD4/8 double-positive transition in thymocyte development.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(6):3526-33.
2005: Noriko Hosoya; Ying Qiao; Akira Hangaishi; Lili Wang; Yasuhito Nannya; Masashi Sanada; Mineo Kurokawa; Shigeru Chiba; Hisamaru Hirai; Seishi Ogawa
Identification of a SRC-like tyrosine kinase gene, FRK, fused with ETV6 in a patient with acute myelogenous leukemia carrying a t(6;12)(q21;p13) translocation.
Genes, chromosomes & cancer 2005;42(3):269-79.
2004: Susumu Goyama; Yoshinobu Kanda; Yasuhito Nannya; Seishi Ogawa; Yuki Asano-Moki; Natsu Ogawa; Masahiro Nakagawa; Mamiko Sakata-Yanagimoto; Masahito Kawazu; Yukiko Komeno; Yoichi Imai; Akira Hangaishi; Mineo Kurokawa; Shiho Tsujino; Katsunori Aoki; Shigeru Chiba; Toru Motokura; Hisamaru Hirai
Clinical significance of peripheral blood erythroblastosis after hematopoietic stem cell transplantation.
Leukemia & lymphoma 2004;45(12):2439-43.
2004: Susumu Goyama; Yuko Yamaguchi; Yoichi Imai; Masahito Kawazu; Masahiro Nakagawa; Takashi Asai; Keiki Kumano; Kinuko Mitani; Seishi Ogawa; Shigeru Chiba; Mineo Kurokawa; Hisamaru Hirai
The transcriptionally active form of AML1 is required for hematopoietic rescue of the AML1-deficient embryonic para-aortic splanchnopleural (P-Sp) region.
Blood 2004;104(12):3558-64.
2004: Motoshi Ichikawa; Takashi Asai; Shigeru Chiba; Mineo Kurokawa; Seishi Ogawa
Runx1/AML-1 ranks as a master regulator of adult hematopoiesis.
Cell cycle (Georgetown, Tex.) 2004;3(6):722-4.
2004: Masahito Kawazu; Yoshinobu Kanda; Yasuhito Nannya; Katsunori Aoki; Mineo Kurokawa; Shigeru Chiba; Toru Motokura; Hisamaru Hirai; Seishi Ogawa
Prospective comparison of the diagnostic potential of real-time PCR, double-sandwich enzyme-linked immunosorbent assay for galactomannan, and a (1-->3)-beta-D-glucan test in weekly screening for invasive aspergillosis in patients with hematological disorders.
Journal of clinical microbiology 2004;42(6):2733-41.
2004: Mamiko Sakata-Yanagimoto; Yoshinobu Kanda; Masahiro Nakagawa; Yuki Asano-Mori; Koji Kandabashi; Koji Izutsu; Yoichi Imai; Akira Hangaishi; Mineo Kurokawa; Shiho Tsujino; Seishi Ogawa; Shigeru Chiba; Toru Motokura; Hisamura Hirai
Predictors for severe cardiac complications after hematopoietic stem cell transplantation.
Bone marrow transplantation 2004;33(10):1043-7.
2004: Yuko Yamaguchi; Mineo Kurokawa; Yoichi Imai; Koji Izutsu; Takashi Asai; Motoshi Ichikawa; Go Yamamoto; Eriko Nitta; Tetsuya Yamagata; Kazuki Sasaki; Kinuko Mitani; Seishi Ogawa; Shigeru Chiba; Hisamaru Hirai
AML1 is functionally regulated through p300-mediated acetylation on specific lysine residues.
The Journal of biological chemistry 2004;279(15):15630-8.
2004: Motoshi Ichikawa; Takashi Asai; Toshiki Saito; Sachiko Seo; Ieharu Yamazaki; Tetsuya Yamagata; Kinuko Mitani; Shigeru Chiba; Seishi Ogawa; Mineo Kurokawa; Hisamaru Hirai
AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis.
Nature medicine 2004;10(3):299-304.
2004: Natsu Ogawa; Yoshinobu Kanda; M Matsubara; Y Asano; Masahiro Nakagawa; Mamiko Sakata-Yanagimoto; Koji Kandabashi; Koji Izutsu; Yoichi Imai; Akira Hangaishi; Mineo Kurokawa; Shiho Tsujino; Seishi Ogawa; Katsunori Aoki; Shigeru Chiba; Toru Motokura; Hisamura Hirai
Increased incidence of acute graft-versus-host disease with the continuous infusion of cyclosporine A compared to twice-daily infusion.
Bone marrow transplantation 2004;33(5):549-52.
2004: Yoichi Imai; Mineo Kurokawa; Yuko Yamaguchi; Koji Izutsu; Eriko Nitta; Kinuko Mitani; Masanobu Satake; Tetsuo Noda; Yoshiaki Ito; Hisamaru Hirai
The corepressor mSin3A regulates phosphorylation-induced activation, intranuclear location, and stability of AML1.
Molecular and cellular biology 2004;24(3):1033-43.
2003: Yukiko Komeno; Seishi Ogawa; Tateru Ishida; Kengo Takeuchi; Shiho Tsujino; Mineo Kurokawa; Katsunori Aoki; Yoshinobu Kanda; Shigeru Chiba; Toru Motokura; Masashi Fukayama; Hisamaru Hirai
Ischemic colitis as a manifestation of thrombotic microangiopathy following bone marrow transplantation.
Internal medicine (Tokyo, Japan) 2003;42(12):1228-32.
2003: Y Asano; Yoshinobu Kanda; Natsu Ogawa; Mamiko Sakata-Yanagimoto; Masahiro Nakagawa; Masahito Kawazu; Susumu Goyama; Koji Kandabashi; Koji Izutsu; Yoichi Imai; Akira Hangaishi; Mineo Kurokawa; Shiho Tsujino; Seishi Ogawa; Katsunori Aoki; Shigeru Chiba; Toru Motokura; Hisamura Hirai
Male predominance among Japanese adult patients with late-onset hemorrhagic cystitis after hematopoietic stem cell transplantation.
Bone marrow transplantation 2003;32(12):1175-9.
2003: Mineo Kurokawa; Hisamaru Hirai
Role of AML1/Runx1 in the pathogenesis of hematological malignancies.
Cancer science 2003;94(10):841-6.
2003: Yukiko Komeno; Yoshinobu Kanda; Koji Kandabashi; Masahito Kawazu; Susumu Goyama; Masataka Takeshita; Yasuhito Nannya; Miyuki Niino; Tetsuya Nakamoto; Mineo Kurokawa; Shiho Tsujino; Seishi Ogawa; Katsunori Aoki; Shigeru Chiba; Toru Motokura; Hisamaru Hirai
Reduced-intensity bone marrow transplantation from an alternative unrelated donor for myelodysplastic syndrome of first-donor origin.
American journal of hematology 2003;72(3):220-2.
2003: Masahito Kawazu; Yoshinobu Kanda; Susumu Goyama; Masataka Takeshita; Yasuhito Nannya; Miyuki Niino; Yukiko Komeno; Tetsuya Nakamoto; Mineo Kurokawa; Shiho Tsujino; Seishi Ogawa; Katsunori Aoki; Shigeru Chiba; Toru Motokura; Nobuya Ohishi; Hisamaru Hirai
Rapid diagnosis of invasive pulmonary aspergillosis by quantitative polymerase chain reaction using bronchial lavage fluid.
American journal of hematology 2003;72(1):27-30.
2002: Susumu Goyama; Yoshinobu Kanda; Yasuhito Nannya; Masahito Kawazu; Masataka Takeshita; Miyuki Niino; Yukiko Komeno; Tetsuya Nakamoto; Mineo Kurokawa; Shiho Tsujino; Seishi Ogawa; Katsunori Aoki; Shigeru Chiba; Toru Motokura; Yasushi Shiratori; Hisamura Hirai
Reverse seroconversion of hepatitis B virus after hematopoietic stem cell transplantation.
Leukemia & lymphoma 2002;43(11):2159-63.
2002: Koji Izutsu; Mineo Kurokawa; Yoichi Imai; Motoshi Ichikawa; Takashi Asai; Kazuhiro Maki; Kinuko Mitani; Hisamaru Hirai
The t(3;21) fusion product, AML1/Evi-1 blocks AML1-induced transactivation by recruiting CtBP.
Oncogene 2002;21(17):2695-703.
2002: Oich Imai; Mineo Kurokawa; Koji Izutsu; Akira Hangaishi; Kazuhiro Maki; Seishi Ogawa; Shigeru Chiba; Kinuko Mitani; Hisamaru Hirai
Mutational analyses of the AML1 gene in patients with myelodysplastic syndrome.
Leukemia & lymphoma 2002;43(3):617-21.
2001: Hisamura Hirai; Koji Izutsu; Mineo Kurokawa; Kinuko Mitani
Oncogenic mechanisms of Evi-1 protein.
Cancer chemotherapy and pharmacology 2001;48 Suppl 1():S35-40.
2001: Koji Izutsu; Mineo Kurokawa; Yoichi Imai; Kazuhiro Maki; Kinuko Mitani; Hisamura Hirai
The corepressor CtBP interacts with Evi-1 to repress transforming growth factor beta signaling.
Blood 2001;97(9):2815-22.
2001: Yoichi Imai; Mineo Kurokawa; Koji Izutsu; Akira Hangaishi; Kazuhiro Maki; Seishi Ogawa; Shigeru Chiba; Kinuko Mitani; Hisamura Hirai
Mutations of the Smad4 gene in acute myelogeneous leukemia and their functional implications in leukemogenesis.
Oncogene 2001;20(1):88-96.
2000: Kinuko Mitani; Tetsuya Yamagata; C Iida; H Oda; Kazuhiro Maki; M Ichikawa; Takashi Asai; Hiroaki Honda; Mineo Kurokawa; Hisamura Hirai
Nonredundant roles of the elongation factor MEN in postimplantation development.
Biochemical and biophysical research communications 2000;279(2):563-7.
2000: Yoichi Imai; Mineo Kurokawa; Koji Izutsu; Akira Hangaishi; Kengo Takeuchi; Kazuhiro Maki; Seishi Ogawa; Shigeru Chiba; Kinuko Mitani; Hisamura Hirai
Mutations of the AML1 gene in myelodysplastic syndrome and their functional implications in leukemogenesis.
Blood 2000;96(9):3154-60.
2000: Kiyoshi Shimizu; Shigeru Chiba; Noriko Hosoya; Keiki Kumano; Toshiki Saito; Mineo Kurokawa; Yoshinobu Kanda; Yoshio Hamada; Hisamura Hirai
Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2.
Molecular and cellular biology 2000;20(18):6913-22.
2000: Mineo Kurokawa; Kinuko Mitani; Tetsuya Yamagata; Tokiharu Takahashi; Koji Izutsu; Seishi Ogawa; T Moriguchi; E Nishida; Yoshio Yazaki; Hisamura Hirai
The evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death.
The EMBO journal 2000;19(12):2958-68.
2000: Mineo Kurokawa; Hisamura Hirai
[Regulation of hematopoiesis by transcription factors].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(9 Suppl):1565-72.
2000: M Horikoshi; Utako Machida; M Itikawa; S Seo; S Masuda; Mineo Kurokawa; Seishi Ogawa; Shinji Sunaga; H Honda; Katsunori Aoki; Shigeru Chiba; Kinuko Mitani; Hisamura Hirai; Yoshio Yazaki
[Essential thrombocythemia in transformation from myelodysplastic syndrome to acute myeloid leukemia with inv(3) after treatment for gastric cancer].
[Rinshō ketsueki] The Japanese journal of clinical hematology 2000;41(1):68-71.
1999: Hisamura Hirai; Seishi Ogawa; Mineo Kurokawa; Yoshio Yazaki; Kinuko Mitani
Molecular characterization of the genomic breakpoints in a case of t(3;21)(q26;q22).
Genes, chromosomes & cancer 1999;26(1):92-6.
1999: Kazuhiro Maki; Kinuko Mitani; Tetsuya Yamagata; Mineo Kurokawa; Yoshinobu Kanda; Yoshio Yazaki; Hisamura Hirai
Transcriptional inhibition of p53 by the MLL/MEN chimeric protein found in myeloid leukemia.
Blood 1999;93(10):3216-24.
1998: Mineo Kurokawa; Kinuko Mitani; Yoichi Imai; Seishi Ogawa; Yoshio Yazaki; Hisamura Hirai
The t(3;21) fusion product, AML1/Evi-1, interacts with Smad3 and blocks transforming growth factor-beta-mediated growth inhibition of myeloid cells.
Blood 1998;92(11):4003-12.
1998: Yoichi Imai; Mineo Kurokawa; Keiichi Tanaka; Alan D Friedman; Seishi Ogawa; Kinuko Mitani; Yoshio Yazaki; Hisamura Hirai
TLE, the human homolog of groucho, interacts with AML1 and acts as a repressor of AML1-induced transactivation.
Biochemical and biophysical research communications 1998;252(3):582-9.
1998: Mineo Kurokawa; Kinuko Mitani; K Irie; T Matsuyama; Tokiharu Takahashi; Shigeru Chiba; Yoshio Yazaki; Kunio Matsumoto; Hisamura Hirai
The oncoprotein Evi-1 represses TGF-beta signalling by inhibiting Smad3.
Nature 1998;394(6688):92-6.
1998: Tokiharu Takahashi; K Yamada; Toshihiro Tanaka; Keiki Kumano; Mineo Kurokawa; Naoto Hirano; Hiroaki Honda; Shigeru Chiba; Kunikazu Tsuji; Yoshio Yazaki; Tatsutoshi Nakahata; Hisamura Hirai
A potential molecular approach to ex vivo hematopoietic expansion with recombinant epidermal growth factor receptor-expressing adenovirus vector.
Blood 1998;91(12):4509-15.
1998: Keiichi Tanaka; Toshihiro Tanaka; Mineo Kurokawa; Yoichi Imai; Seishi Ogawa; Kinuko Mitani; Yoshio Yazaki; Hisamura Hirai
The AML1/ETO(MTG8) and AML1/Evi-1 leukemia-associated chimeric oncoproteins accumulate PEBP2beta(CBFbeta) in the nucleus more efficiently than wild-type AML1.
Blood 1998;91(5):1688-99.
1998: Yoshinobu Kanda; Kinuko Mitani; Mineo Kurokawa; Tetsuya Yamagata; Yoshio Yazaki; Hisamura Hirai
Overexpression of the MEN/ELL protein, an RNA polymerase II elongation factor, results in transformation of Rat1 cells with dependence on the lysine-rich region.
The Journal of biological chemistry 1998;273(9):5248-52.
1997: Hisamura Hirai; Seishi Ogawa; Akira Hangaishi; Tokiharu Takahashi; Mineo Kurokawa; Kinuko Mitani; R Ueda; Yoshio Yazaki
Recent progress in molecular mechanisms of leukemogenesis: the cyclin-dependent kinase 4-inhibitor gene in human leukemias.
Leukemia 1997;11 Suppl 3():358-60.
1997: Toshihiro Tanaka; Keiichi Tanaka; Seishi Ogawa; Mineo Kurokawa; Kinuko Mitani; Yoshio Yazaki; Y Shibata; Hisamura Hirai
An acute myeloid leukemia gene, AML1, regulates transcriptional activation and hemopoietic myeloid cell differentiation antagonistically by two alternative spliced forms.
Leukemia 1997;11 Suppl 3():299-302.
1996: Seishi Ogawa; Kinuko Mitani; Mineo Kurokawa; Y Matsuo; J Minowada; Johji Inazawa; N Kamada; T Tsubota; Y Yazaki; H Hirai
Abnormal expression of Evi-1 gene in human leukemias.
Human cell 1996;9(4):323-32.
1996: Mineo Kurokawa; T Tanaka; K Tanaka; Naoto Hirano; Seishi Ogawa; Kinuko Mitani; Y Yazaki; H Hirai
A conserved cysteine residue in the runt homology domain of AML1 is required for the DNA binding ability and the transforming activity on fibroblasts.
The Journal of biological chemistry 1996;271(28):16870-6.
1996: Seishi Ogawa; Mineo Kurokawa; T Tanaka; Kinuko Mitani; Johji Inazawa; Akira Hangaishi; K Tanaka; Y Matsuo; J Minowada; T Tsubota; Y Yazaki; H Hirai
Structurally altered Evi-1 protein generated in the 3q21q26 syndrome.
Oncogene 1996;13(1):183-91.
1996: T Tanaka; Mineo Kurokawa; Keisuke Ueki; K Tanaka; Yoichi Imai; Kinuko Mitani; K Okazaki; N Sagata; Y Yazaki; Y Shibata; Takashi Kadowaki; H Hirai
The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability.
Molecular and cellular biology 1996;16(7):3967-79.
1996: Seishi Ogawa; Mineo Kurokawa; T Tanaka; K Tanaka; Akira Hangaishi; Kinuko Mitani; N Kamada; Y Yazaki; H Hirai
Increased Evi-1 expression is frequently observed in blastic crisis of chronic myelocytic leukemia.
Leukemia 1996;10(5):788-94.
1996: Mineo Kurokawa; T Tanaka; K Tanaka; Seishi Ogawa; Kinuko Mitani; Y Yazaki; H Hirai
Overexpression of the AML1 proto-oncoprotein in NIH3T3 cells leads to neoplastic transformation depending on the DNA-binding and transactivational potencies.
Oncogene 1996;12(4):883-92.
1995: Mineo Kurokawa; Seishi Ogawa; T Tanaka; Kinuko Mitani; Y Yazaki; O N Witte; H Hirai
The AML1/Evi-1 fusion protein in the t(3;21) translocation exhibits transforming activity on Rat1 fibroblasts with dependence on the Evi-1 sequence.
Oncogene 1995;11(5):833-40.
1995: Kinuko Mitani; Seishi Ogawa; T Tanaka; Mineo Kurokawa; Y Yazaki; H Hirai
Growth inhibition of leukaemic cells carrying the t(3;21) by the AML1/EVI-1-specific antisense oligonucleotide.
British journal of haematology 1995;90(3):711-4.
1995: K Tanaka; T Tanaka; Seishi Ogawa; Mineo Kurokawa; Kinuko Mitani; Y Yazaki; H Hirai
Increased expression of AML1 during retinoic-acid-induced differentiation of U937 cells.
Biochemical and biophysical research communications 1995;211(3):1023-30.
1995: T Tanaka; Kinuko Mitani; Mineo Kurokawa; Seishi Ogawa; K Tanaka; J Nishida; Y Yazaki; Y Shibata; H Hirai
Dual functions of the AML1/Evi-1 chimeric protein in the mechanism of leukemogenesis in t(3;21) leukemias.
Molecular and cellular biology 1995;15(5):2383-92.
1995: T Tanaka; K Tanaka; Seishi Ogawa; Mineo Kurokawa; Kinuko Mitani; J Nishida; Y Shibata; Y Yazaki; H Hirai
An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms.
The EMBO journal 1995;14(2):341-50.
1994: Seishi Ogawa; Naoto Hirano; N Sato; T Takahashi; Akira Hangaishi; K Tanaka; Mineo Kurokawa; T Tanaka; Kinuko Mitani; Y Yazaki
Homozygous loss of the cyclin-dependent kinase 4-inhibitor (p16) gene in human leukemias.
Blood 1994;84(8):2431-5.
1994: Kinuko Mitani; Seishi Ogawa; T Tanaka; H Miyoshi; Mineo Kurokawa; H Mano; Y Yazaki; Misao Ohki; H Hirai
Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia.
The EMBO journal 1994;13(3):504-10.