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R Kurrle

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Chemicals & Drugs

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Graft vs Host Reaction

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Publications

TOP 3
J Czech; R Kurrle; HU Schorlemmer
The antiproliferative effect of malononitrilamides (MNAs) on vascular smooth muscle cells is antagonized by exogenous uridine.
HU Schorlemmer; R Kurrle; R Schleyerbach; RR Bartlett
Generation of O2- radicals in macrophages can be inhibited in vitro and in vivo by derivatives of leflunomide's primary metabolite.
HU Schorlemmer; R Kurrle; R Schleyerbach; RR Bartlett
Disease-modifying activity of malononitrilamides, derivatives of leflunomide's active metabolite, on models of rheumatoid arthritis.

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All Publications

1999: J Czech; R Kurrle; HU Schorlemmer
The antiproliferative effect of malononitrilamides (MNAs) on vascular smooth muscle cells is antagonized by exogenous uridine.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1999;48 Suppl 2():S128-9.
1999: HU Schorlemmer; R Kurrle; R Schleyerbach; RR Bartlett
Generation of O2- radicals in macrophages can be inhibited in vitro and in vivo by derivatives of leflunomide's primary metabolite.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1999;48 Suppl 2():S117-8.
1999: HU Schorlemmer; R Kurrle; R Schleyerbach; RR Bartlett
Disease-modifying activity of malononitrilamides, derivatives of leflunomide's active metabolite, on models of rheumatoid arthritis.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1999;48 Suppl 2():S113-4.
1999: HU Schorlemmer; R Kurrle; R Schleyerbach; RR Bartlett
In vivo lymphoproliferation in the popliteal lymph node (PLN) assay can be inhibited by leflunomide's active metabolite A77 1726.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1999;48 Suppl 2():S111-2.
1999: HU Schorlemmer; RR Bartlett; J K Lindner; R Kurrle
Coadministration of malononitrilamides and tacrolimus induces tolerance in a rat skin allograft model.
Transplantation proceedings 1999;31(1-2):1184-8.
1999: HU Schorlemmer; RR Bartlett; R Kurrle
Malononitrilamides prevent the generation of oxygen radicals in mononuclear phagocytes and graft rejection in a rat model.
Transplantation proceedings 1999;31(1-2):851-3.
1998: HU Schorlemmer; R Kurrle
Combination therapy of malononitrilamides and tacrolimus (FK 506) induced long-term xenograft survival.
Transplantation proceedings 1998;30(8):4170-3.
1998: HU Schorlemmer; RR Bartlett; J K Lindner; R Kurrle
Long-term allograft survival and tolerance induction by the synergistic activity of malononitrilamides and tacrolimus.
Transplantation proceedings 1998;30(8):4099-103.
1998: HU Schorlemmer; R Kurrle
Malononitrilamides reduce IgM and IgG xenoantibodies and prolong skin xenograft survival in a mouse-to rat model.
Transplantation proceedings 1998;30(4):976-9.
1998: HU Schorlemmer; RR Bartlett; R Kurrle
Inhibition of alloreactivity in the popliteal lymph node assay by malononitrilamides.
Transplantation proceedings 1998;30(4):968-70.
1998: HU Schorlemmer; R Kurrle
Hyperacute skin allograft rejection in presensitized rats is abrogated by malononitrilamides.
Transplantation proceedings 1998;30(4):963-7.
1998: HU Schorlemmer; R Bartlett; R Kurrle
Malononitrilamides: a new strategy of immunosuppression for allo- and xenotransplantation.
Transplantation proceedings 1998;30(3):884-90.
1998: HU Schorlemmer; E Ruuth; R Kurrle
Regulation of alloreactivity in the popliteal lymph node assay by the new immunosuppressants: malononitrilamides.
Transplant international : official journal of the European Society for Organ Transplantation 1998;11 Suppl 1():S448-51.
1998: HU Schorlemmer; E Ruuth; R Kurrle
Malononitrilamides synergistically prevent acute and treat ongoing skin allograft rejection with cyclosporine.
Transplant international : official journal of the European Society for Organ Transplantation 1998;11 Suppl 1():S340-4.
1997: HU Schorlemmer; R Kurrle
Long-term xenograft survival by combination therapy of malononitrilamide MNA 715 with cyclosporine.
Transplantation proceedings 1997;29(8):3501-4.
1997: HU Schorlemmer; R Kurrle
The new immunosuppressive malononitrilamide MNA 279 prolongs skin xenograft survival in a mouse-to-rat model.
Transplantation proceedings 1997;29(8):3497-500.
1997: HU Schorlemmer; R Kurrle; RR Bartlett
Various graft vs. host diseases (GvHD) in rodents can be prevented and treated by malononitrilamides (MNAs).
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1997;46 Suppl 2():S165-6.
1997: R Kurrle; E Ruuth; R Bartlett; L Lauffer; HU Schorlemmer
Malononitrilamides inhibit T- and B-cell responsiveness in different species.
Transplantation proceedings 1997;29(1-2):1302-3.
1997: HU Schorlemmer; RR Bartlett; R Kurrle
Analogues of leflunomide's primary metabolite, the malononitrilamides, prevent the development of graft-versus-host disease.
Transplantation proceedings 1997;29(1-2):1298-301.
1997: HU Schorlemmer; R Kurrle; RR Bartlett
The new immunosuppressants, the malononitrilamides MNA 279 and MNA 715, inhibit various graft-vs.-host diseases (GvHD) in rodents.
Drugs under experimental and clinical research 1997;23(5-6):167-73.
1997: HU Schorlemmer; E Ruuth; R Kurrle
The alloreactivity in the popliteal lymph node (PLN) assay is regulated by malononitrilamides (MNAs).
International journal of tissue reactions 1997;19(3-4):157-61.
1997: HU Schorlemmer; R Kurrle
Synergistic activity of malononitrilamides with cyclosporine to control and reverse xenograft rejection.
International journal of tissue reactions 1997;19(3-4):149-56.
1996: R Kurrle; R Bartlett; E Ruuth; L Lauffer; HU Schorlemmer
Malononitrilamides inhibit T- and B-cell responsiveness.
Transplantation proceedings 1996;28(6):3053-6.
1996: HU Schorlemmer; W Schwab; E Ruuth; R Kurrle
Acute skin graft rejection can be prevented and treated in rat models by malononitrilamides.
Transplantation proceedings 1996;28(6):3048-50.
1996: HU Schorlemmer; R Kurrle; RR Bartlett
Malononitrilamides inhibit the development of various murine graft-vs-host diseases.
Transplantation proceedings 1996;28(6):3043-7.
1996: HU Schorlemmer; R Kurrle
Control of mouse-to-rat skin xenograft rejection by malononitrilamides.
Transplantation proceedings 1996;28(6):3037-9.
1995: Uwe Schauer; M Schmitt; S Müller; K Enssle; R Kurrle; U Sundermann; A Bender; U Wahn; Christian H L Rieger
Soluble interleukin-4 receptor in atopic children.
International archives of allergy and immunology 1995;108(2):175-82.
1995: R Kurrle; L Lauffer; J Röder; E J Kanzy; K H Enssle; F R Seiler
Regulation of IL-1 activity by soluble IL-1 receptors.
Behring Institute Mitteilungen 1995;(96):45-57.
1995: L Lauffer; E J Kanzy; R Köhler; R Kurrle; K Enssle; F R Seiler
Monomeric and dimeric forms of soluble receptors can differ in their neutralization potential.
Behring Institute Mitteilungen 1995;(96):21-31.
1995: K Enssle; B Enders; R Kurrle; L Lauffer; HU Schorlemmer; G Dickneite; E J Kanzy; F R Seiler
Biology of natural and recombinant soluble interleukin-4 receptor.
Behring Institute Mitteilungen 1995;(96):103-17.
1995: HU Schorlemmer; G Dickneite; R Kurrle; F R Seiler
Synergistic effects of 15-deoxyspergualin with cyclosporine and the TCR-targeted monoclonal antibody R73 to induce specific unresponsiveness to skin allografts in rats.
Transplantation proceedings 1995;27(1):414-6.
1995: H Renz; K Enssle; L Lauffer; R Kurrle; Erwin W Gelfand
Inhibition of allergen-induced IgE and IgG1 production by soluble IL-4 receptor.
International archives of allergy and immunology 1995;106(1):46-54.
1995: S Hess; R Kurrle; L Lauffer; Gert Riethmüller; Hartmut Engelmann
A cytotoxic CD40/p55 tumor necrosis factor receptor hybrid detects CD40 ligand on herpesvirus saimiri-transformed T cells.
European journal of immunology 1995;25(1):80-6.
1993: HU Schorlemmer; E J Kanzy; K D Langner; R Kurrle
Immunoregulation of SLE-like disease by the IL-1 receptor: disease modifying activity on BDF1 hybrid mice and MRL autoimmune mice.
Agents and actions 1993;39 Spec No():C117-20.
1993: HU Schorlemmer; E J Kanzy; K D Langner; R Kurrle
Immunomodulatory activity of recombinant IL-1 receptor (IL-1-R) on models of experimental rheumatoid arthritis.
Agents and actions 1993;39 Spec No():C113-6.
1991: K Enssle; R Kurrle; R Köhler; H Müller; E J Kanzy; J Hilfenhaus; F R Seiler
A rabies-specific human monoclonal antibody that protects mice against lethal rabies.
Hybridoma 1991;10(5):547-56.
1991: HU Schorlemmer; E J Kanzy; R Kurrle; F R Seiler
Inhibitory effects of the anti-rat T-cell receptor (TCR) monoclonal antibody (MAb) R73 on various experimental autoimmune diseases.
Agents and actions 1991;34(1-2):161-4.
1991: R Kurrle; HU Schorlemmer; C Shearman; L Lauffer; K Frank; E J Kanzy; F R Seiler
Analysis of the immunoregulatory capacity of anti-alpha/beta-TCR and anti-CD3 monoclonal antibodies.
Transplantation proceedings 1991;23(1 Pt 1):272-6.
1990: D Krause; C Shearman; W Lang; E J Kanzy; R Kurrle
Determination of affinities of murine and chimeric anti alpha/beta-T-cell receptor antibodies by flow cytometry.
Behring Institute Mitteilungen 1990;(87):56-67.
1990: S Smely; M Weschka; Günter F Hillebrand; Ulrich Dendorfer; Fritz Krombach; R Kurrle; Walter Land; C Hammer
Prophylactic use of the new monoclonal antibody BMA 031 in clinical kidney transplantation.
Transplantation proceedings 1990;22(4):1785-6.
1988: R Kurrle; K H Enssle; F R Seiler
Monoclonal antibodies directed to leukocyte differentiation antigens for therapeutic use.
Behring Institute Mitteilungen 1988;(82):154-73.