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Hitoshi Kusaba

Research Profile

Procedures

Antineoplastic Combined Chemotherapy Protocols

Anatomy

Tumor Cell Line

Chemicals & Drugs

Disorders

Physiology

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Yeast Artificial Chromosomes

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Hitoshi Kusaba; Kenji Mitsugi; Keita Uchino; Koichi Akashi; Shuji Arita; Taito Esaki; Junji Kishimoto; Hozumi Kumagai; Eishi Baba
Phase I study of bevacizumab combined with irinotecan and S-1 as second-line chemotherapy in patients with advanced colorectal cancer.
Eishi Baba; Hitoshi Kusaba; Shuji Nakano
[Development trends for therapeutic antibody].
Keita Uchino; Eishi Baba; Minako Hirahashi; Gen Hirano; Taichi Isobe; Hitoshi Kusaba; Tsuyoshi Shirakawa; Masazumi Tsuneyoshi; Koichi Akashi
Human Nanog pseudogene8 promotes the proliferation of gastrointestinal cancer cells.

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2013: Hitoshi Kusaba; Kenji Mitsugi; Keita Uchino; Koichi Akashi; Shuji Arita; Taito Esaki; Junji Kishimoto; Hozumi Kumagai; Eishi Baba
Phase I study of bevacizumab combined with irinotecan and S-1 as second-line chemotherapy in patients with advanced colorectal cancer.
Cancer chemotherapy and pharmacology 2013;71(1):29-34.
2012: Eishi Baba; Hitoshi Kusaba; Shuji Nakano
[Development trends for therapeutic antibody].
Nihon rinsho. Japanese journal of clinical medicine 2012;70(12):2098-103.
2012: Keita Uchino; Eishi Baba; Minako Hirahashi; Gen Hirano; Taichi Isobe; Hitoshi Kusaba; Tsuyoshi Shirakawa; Masazumi Tsuneyoshi; Koichi Akashi
Human Nanog pseudogene8 promotes the proliferation of gastrointestinal cancer cells.
Experimental cell research 2012;318(15):1799-807.
2012: Eishi Baba; Taito Esaki; Hiromitsu Fujishima; Hitoshi Kusaba; Akitaka Makiyama; Kenji Mitsugi; Shuji Nakano; Risa Tanaka; Keita Uchino; Koichi Akashi
Phase 2 study of modified irinotecan and bolus 5-fluorouracil/l-leucovorin in Japanese metastatic colorectal cancer patients.
Advances in therapy 2012;29(3):287-96.
2012: Hozumi Kumagai; Hitoshi Kusaba; Ryo Maeyama; Eishi Nagai; Kenta Nio; Tsuyoshi Shirakawa; Shingo Tamura; Keita Uchino; Koichi Akashi; Taichi Isobe; Masato Komoda; Eishi Baba
Improvement of quality of life and survival using self-expandable metal stent placement for severe malignant stenosis of the gastric body: a case report.
Journal of medical case reports 2012;6(1):315.
2011: Taichi Isobe; Masato Komoda; Hitoshi Kusaba; Tsuyoshi Shirakawa; Shigeo Takaishi; Shingo Tamura; Takashi Ueki; Shuji Arita; Hiroshi Ariyama; Eishi Baba; Koichi Akashi
Human STEAP3 maintains tumor growth under hypoferric condition.
Experimental cell research 2011;317(18):2582-91.
2011: Eishi Baba; Taito Esaki; Hiromitsu Fujishima; Hitoshi Kusaba; Kenji Mitsugi; Tatsuma Morikita; Shuji Nakano; Hiroshi Ariyama; Koichi Akashi
Phase II study of sequential treatment with S-1 and cisplatin for metastatic gastric cancer.
Cancer chemotherapy and pharmacology 2011;68(3):611-7.
2010: Hitoshi Kusaba; Taito Esaki; Kitaro Futami; Sinnosuke Tanaka; Hiromitsu Fujishima; Kenji Mitsugi; Kenji Sakai; Hiroshi Ariyama; Risa Tanaka; Naoko Kinugawa; Takashi Ueki; Rhuichi Mibu; Eishi Baba; Shuji Nakano; Koichi Akashi
Phase I/II study of a 3-week cycle of irinotecan and S-1 in patients with advanced colorectal cancer.
Cancer science 2010;101(12):2591-5.
2010: Hiroshi Ariyama; Hitoshi Kusaba; Eishi Baba
[Cetuximab for patients with metastatic colorectal cancer-from the result of recent clinical trials].
Gan to kagaku ryoho. Cancer & chemotherapy 2010;37(5):782-6.
2009: Yoshihiro Shibata; Hiroshi Ariyama; Eishi Baba; Yasushi Takii; Taito Esaki; Kenji Mitsugi; Tanji Tsuchiya; Hitoshi Kusaba; Koichi Akashi; Shuji Nakano
Oxaliplatin-induced allergic reaction in patients with colorectal cancer in Japan.
International journal of clinical oncology 2009;14(5):397-401.
2009: Eishi Baba; Hiromitsu Fujishima; Hitoshi Kusaba; Taito Esaki; Hiroshi Ariyama; Ken Kato; Risa Tanaka; Kenji Mitsugi; Yoshihiro Shibata; Mine Harada; Shuji Nakano
Phase I study of the sequential administration of S-1 and cisplatin for metastatic gastric cancer.
Anticancer research 2009;29(5):1727-32.
2009: Akitaka Makiyama; Baoli Qin; Keita Uchino; Yoshihiro Shibata; Shuji Arita; Taichi Isobe; Gen Hirano; Hitoshi Kusaba; Eishi Baba; Koichi Akashi; Shuji Nakano
Schedule-dependent synergistic interaction between gemcitabine and oxaliplatin in human gallbladder adenocarcinoma cell lines.
Anti-cancer drugs 2009;20(2):123-30.
2009: Taichi Isobe; Shunichi Yanai; Hitoshi Kusaba; Shinichiro Yada; Yosuke Kuroda; Sadafumi Tamiya; Takayuki Matsumoto; Eishi Baba; Mine Harada
Effective monotherapy with amrubicin for a refractory extrapulmonary small-cell carcinoma of the liver.
Case reports in medicine 2009;2009():538081.
2008: Shuji Arita; Eishi Baba; Yoshihiro Shibata; Hiroaki Niiro; Shinji Shimoda; Taichi Isobe; Hitoshi Kusaba; Shuji Nakano; Mine Harada
B cell activation regulates exosomal HLA production.
European journal of immunology 2008;38(5):1423-34.
2008: Hitoshi Kusaba; Masahiko Fujihara; Ryuichi Nagashima; Yoshikazu Kaji; Eishi Baba; Shuji Nakano
Systemic chemotherapy of TS-1 and cisplatin for gastric signet-ring cell carcinoma presenting as cardiac tamponade.
Medical oncology (Northwood, London, England) 2008;25(2):241-4.
2007: Yoshihiro Shibata; Eishi Baba; Hiroshi Ariyama; Ryusuke Miki; Nobumichi Ogami; Shuji Arita; Baoli Qin; Hitoshi Kusaba; Kenji Mitsugi; Hirokazu Noshiro; Takashi Yao; Shuji Nakano
Metastatic basaloid-squamous cell carcinoma of the esophagus treated by 5-fluorouracil and cisplatin.
World journal of gastroenterology : WJG 2007;13(26):3634-7.
2007: Hitoshi Kusaba; Yoshihiro Shibata; Shuji Arita; Hiroshi Ariyama; Eishi Baba; Kenji Mitsugi; Mine Harada; Shuji Nakano
Infusional 5-fluorouracil and cisplatin as first-line chemotherapy in patients with carcinoma of unknown primary site.
Medical oncology (Northwood, London, England) 2007;24(2):259-64.
2006: Baoli Qin; Hiroshi Ariyama; Eishi Baba; Risa Tanaka; Hitoshi Kusaba; Mine Harada; Shuji Nakano
Activated Src and Ras induce gefitinib resistance by activation of signaling pathways downstream of epidermal growth factor receptor in human gallbladder adenocarcinoma cells.
Cancer chemotherapy and pharmacology 2006;58(5):577-84.
2006: Baoli Qin; Risa Tanaka; Yoshihiro Shibata; Shuji Arita; Hiroshi Ariyama; Hitoshi Kusaba; Eishi Baba; Mine Harada; Shuji Nakano
In-vitro schedule-dependent interaction between oxaliplatin and 5-fluorouracil in human gastric cancer cell lines.
Anti-cancer drugs 2006;17(4):445-53.
2006: Baoli Qin; Risa Tanaka; Hiroshi Ariyama; Yoshihiro Shibata; Shuji Arita; Hitoshi Kusaba; Eishi Baba; Mine Harada; Shuji Nakano
In-vitro differential metabolism and activity of 5-fluorouracil between short-term, high-dose and long-term, low-dose treatments in human squamous carcinoma cells.
Anti-cancer drugs 2006;17(4):439-43.
2005: Risa Tanaka; Hiroshi Ariyama; Baoli Qin; Yoshihiro Shibata; Yasushi Takii; Hitoshi Kusaba; Eishi Baba; Kenji Mitsugi; Mine Harada; Shuji Nakano
Synergistic interaction between oxaliplatin and SN-38 in human gastric cancer cell lines in vitro.
Oncology reports 2005;14(3):683-8.
2005: Risa Tanaka; Yasushi Takii; Yoshihiro Shibata; Hiroshi Ariyama; Baoli Qin; Eishi Baba; Hitoshi Kusaba; Kenji Mitsugi; Mine Harada; Shuji Nakano
In vitro sequence-dependent interaction between nedaplatin and paclitaxel in human cancer cell lines.
Cancer chemotherapy and pharmacology 2005;56(3):279-85.
2001: Junya Nagayama; M Iino; Yasuhiro Tada; Hitoshi Kusaba; A Kiue; Koichi Ohshima; Michihiko Kuwano; Morimasa Wada
Retrovirus insertion and transcriptional activation of the multidrug-resistance gene in leukemias treated by a chemotherapeutic agent in vivo.
Blood 2001;97(3):759-66.
2000: Hitoshi Kusaba; N Saijo
[A summary report of response evaluation criteria in solid tumors (RECIST criteria)].
Gan to kagaku ryoho. Cancer & chemotherapy 2000;27(1):1-5.
1999: Hitoshi Kusaba; Kenji Mitsugi; Shuji Nakano; N Saijo
[Problems and prospects for combined chemotherapy with 5-fluorouracil and low-dose cisplatin].
Gan to kagaku ryoho. Cancer & chemotherapy 1999;26(11):1575-80.
1999: Hitoshi Kusaba; M Nakayama; Taishi Harada; M Nomoto; Kimitoshi Kohno; Michihiko Kuwano; Morimasa Wada
Association of 5' CpG demethylation and altered chromatin structure in the promoter region with transcriptional activation of the multidrug resistance 1 gene in human cancer cells.
European journal of biochemistry / FEBS 1999;262(3):924-32.
1998: M Nakayama; Morimasa Wada; Taishi Harada; Junya Nagayama; Hitoshi Kusaba; Koichi Ohshima; Mitsuo Kozuru; H Komatsu; R Ueda; Michihiko Kuwano
Hypomethylation status of CpG sites at the promoter region and overexpression of the human MDR1 gene in acute myeloid leukemias.
Blood 1998;92(11):4296-307.
1998: K Torigoe; Taishi Harada; Hitoshi Kusaba; Takeshi Uchiumi; Kimitoshi Kohno; Eric Green; S W Scherer; L C Tsui; David Schlessinger; Michihiko Kuwano; Morimasa Wada
Localization of 67 exons on a YAC contig spanning 1.5 Mb around the multidrug resistance gene region of human chromosome 7q21.1.
Genomics 1998;49(1):14-22.
1997: Hitoshi Kusaba; M Nakayama; Taishi Harada; K Torigoe; Eric Green; S W Scherer; Kimitoshi Kohno; Michihiko Kuwano; Morimasa Wada
Maintenance of hypomethylation status and preferential expression of exogenous human MDR1/PGY1 gene in mouse L cells by YAC mediated transfer.
Somatic cell and molecular genetics 1997;23(4):259-74.
1995: Hitoshi Kusaba; Kimitoshi Kohno; K Asakuno; Michihiko Kuwano; Koji Okumura; Eric Green; David Schlessinger; Morimasa Wada
Functional expression of yeast artificial chromosome-human multidrug resistance genes in mouse cells.
Genome research 1995;5(3):245-58.
1995: K Torigoe; S Sato; Hitoshi Kusaba; Kimitoshi Kohno; Michihiko Kuwano; Koji Okumura; Eric Green; L C Tsui; S W Scherer; David Schlessinger; M Wada
A YAC-based contig of 1.5 Mb spanning the human multidrug resistance gene region and delineating the amplification unit in three human multidrug-resistant cell lines.
Genome research 1995;5(3):233-44.
1993: Hitoshi Kusaba; J Kudo; T Kuruma; R Nagashima; M Ra; T Mori; Yoshikazu Kaji; Hiromi Ishibashi; Y Niho; Y Baba
[Interferon therapy after ablation of Kent bundle for a patient with chronic hepatitis type B complicated with WPW syndrome].
Fukuoka igaku zasshi = Hukuoka acta medica 1993;84(6):330-3.