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Olga Kustikova

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Martijn Brugman; Olga S Kustikova; Ute Modlich; Michael Rothe; Axel Schambach; Sebastian Suerbaum; Julia D Suerth; Christopher Baum
Evaluating a ligation-mediated PCR and pyrosequencing method for the detection of clonal contribution in polyclonal retrovirally transduced samples.
Olga S Kustikova; Zhixiong Li; T Neumann; Ingo Roeder; Axel Schambach; Brigitte Schlegelberger; A Schwarzer; M Stahlhut; Doris Steinemann; M Yang; Martijn Brugman; S Gerdes; T C Ha; N Heinz; Christopher Baum
Activation of Evi1 inhibits cell cycle progression and differentiation of hematopoietic progenitor cells.
Tobias Maetzig; Martijn Brugman; Stefan Bartels; Niels Heinz; Olga S Kustikova; Ute Modlich; Zhixiong Li; Melanie Galla; Bernhard Schiedlmeier; Axel Schambach; Christopher Baum
Polyclonal fluctuation of lentiviral vector-transduced and expanded murine hematopoietic stem cells.

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All Publications

2013: Martijn Brugman; Olga S Kustikova; Ute Modlich; Michael Rothe; Axel Schambach; Sebastian Suerbaum; Julia D Suerth; Christopher Baum
Evaluating a ligation-mediated PCR and pyrosequencing method for the detection of clonal contribution in polyclonal retrovirally transduced samples.
Human gene therapy methods 2013;24(2):68-79.
2013: Olga S Kustikova; Zhixiong Li; T Neumann; Ingo Roeder; Axel Schambach; Brigitte Schlegelberger; A Schwarzer; M Stahlhut; Doris Steinemann; M Yang; Martijn Brugman; S Gerdes; T C Ha; N Heinz; Christopher Baum
Activation of Evi1 inhibits cell cycle progression and differentiation of hematopoietic progenitor cells.
Leukemia 2013;27(5):1127-38.
2011: Tobias Maetzig; Martijn Brugman; Stefan Bartels; Niels Heinz; Olga S Kustikova; Ute Modlich; Zhixiong Li; Melanie Galla; Bernhard Schiedlmeier; Axel Schambach; Christopher Baum
Polyclonal fluctuation of lentiviral vector-transduced and expanded murine hematopoietic stem cells.
Blood 2011;117(11):3053-64.
2010: Olga S Kustikova; Martijn Brugman; Christopher Baum
The genomic risk of somatic gene therapy.
Seminars in cancer biology 2010;20(4):269-78.
2009: Olga S Kustikova; Bernhard Schiedlmeier; Martijn Brugman; Maike Stahlhut; Stefan Bartels; Zhixiong Li; Christopher Baum
Cell-intrinsic and vector-related properties cooperate to determine the incidence and consequences of insertional mutagenesis.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(9):1537-47.
2009: Olga S Kustikova; Ute Modlich; Boris Fehse
Retroviral insertion site analysis in dominant haematopoietic clones.
Methods in molecular biology (Clifton, N.J.) 2009;506():373-90.
2008: Olga S Kustikova; Christopher Baum; Boris Fehse
Retroviral integration site analysis in hematopoietic stem cells.
Methods in molecular biology (Clifton, N.J.) 2008;430():255-67.
2007: Johann Meyer; M Rhein; Bernhard Schiedlmeier; Olga S Kustikova; Cornelia Rudolph; Kenji Kamino; T Neumann; M Yang; Anke Wahlers; Boris Fehse; Gary W Reuther; Brigitte Schlegelberger; Arnold Ganser; Christopher Baum; Zhixiong Li
Remarkable leukemogenic potency and quality of a constitutively active neurotrophin receptor, deltaTrkA.
Leukemia 2007;21(10):2171-80.
2007: Zhixiong Li; Olga S Kustikova; Kenji Kamino; Thomas Neumann; Mathias Rhein; Elke Grassman; Boris Fehse; Christopher Baum
Insertional mutagenesis by replication-deficient retroviral vectors encoding the large T oncogene.
Annals of the New York Academy of Sciences 2007;1106():95-113.
2007: Olga S Kustikova; Hartmut Geiger; Zhixiong Li; Martijn Brugman; Stuart M Chambers; Chad A Shaw; Karin Pike-Overzet; Dick de Ridder; Frank Staal; Gottfried von Keudell; Kerstin Cornils; Kalpana J Nattamai; Ute Modlich; Gerard Wagemaker; Margaret A Goodell; Boris Fehse; Christopher Baum
Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways.
Blood 2007;109(5):1897-907.
2006: Christopher Baum; Olga S Kustikova; Ute Modlich; Zhixiong Li; Boris Fehse
Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors.
Human gene therapy 2006;17(3):253-63.
2005: Ute Modlich; Olga S Kustikova; Manfred Schmidt; Cornelia Rudolph; Johann Meyer; Zhixiong Li; Kenji Kamino; Nils von neuhoff; Brigitte Schlegelberger; Klaus Kuehlcke; Kevin D Bunting; Sonja Schmidt; Annette Deichmann; Christof von Kalle; Boris Fehse; Christopher Baum
Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis.
Blood 2005;105(11):4235-46.
2005: Olga S Kustikova; Boris Fehse; Ute Modlich; Min Yang; Jochen Düllmann; Kenji Kamino; Nils von neuhoff; Brigitte Schlegelberger; Zhixiong Li; Christopher Baum
Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking.
Science (New York, N.Y.) 2005;308(5725):1171-4.
2004: Sergey S Larin; Elena V Korobko; Olga S Kustikova; Olga R Borodulina; Natan T Raikhlin; Igor P Brisgalov; Georgii P Georgiev; Sergey L Kiselev
Immunotherapy with autologous tumor cells engineered to secrete Tag7/PGRP, an innate immunity recognition molecule.
The journal of gene medicine 2004;6(7):798-808.
2004: Boris Fehse; Olga S Kustikova; M Bubenheim; Christopher Baum
Pois(s)on--it's a question of dose...
Gene therapy 2004;11(11):879-81.
2003: Olga S Kustikova; Anke Wahlers; Klaus Kuhlcke; Birgit Stahle; Axel R Zander; Christopher Baum; Boris Fehse
Dose finding with retroviral vectors: correlation of retroviral vector copy numbers in single cells with gene transfer efficiency in a cell population.
Blood 2003;102(12):3934-7.
2002: Boris Fehse; Olga S Kustikova; Zhixiong Li; Anke Wahlers; Wolfgang Bohn; W R Beyer; D Chalmers; P Tiberghien; Klaus Kühlcke; Axel R Zander; Christopher Baum
A novel 'sort-suicide' fusion gene vector for T cell manipulation.
Gene therapy 2002;9(23):1633-8.
2002: Anke Wahlers; Olga S Kustikova; Peter F Zipfel; Katsuhiko Itoh; Markus Koester; Christoph Heberlein; Zhixiong Li; Bernhard Schiedlmeier; Christine Skerka; Boris Fehse; Christopher Baum
Upstream conserved sequences of mouse leukemia viruses are important for high transgene expression in lymphoid and hematopoietic cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(3):313-20.
2002: Henriette Andersen; Shaukat Mahmood; Vadim Tkach; Martin Cohn; Olga S Kustikova; Mariam Grigorian; Vladimir Berezin; Elisabeth Bock; Eugene Lukanidin; Eugene Tulchinsky
The ability of Fos family members to produce phenotypic changes in epithelioid cells is not directly linked to their transactivation potentials.
Oncogene 2002;21(31):4843-8.
1998: Olga S Kustikova; D Kramerov; Mariam Grigorian; Vladimir Berezin; Elisabeth Bock; Eugene Lukanidin; Eugene Tulchinsky
Fra-1 induces morphological transformation and increases in vitro invasiveness and motility of epithelioid adenocarcinoma cells.
Molecular and cellular biology 1998;18(12):7095-105.
1998: Sergey L Kiselev; Olga S Kustikova; Elena V Korobko; Egor Prokhortchouk; A A Kabishev; Eugene Lukanidin; Georgii P Georgiev
Molecular cloning and characterization of the mouse tag7 gene encoding a novel cytokine.
The Journal of biological chemistry 1998;273(29):18633-9.