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Hiroto Kuwabara

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Andrew G Horti; Jianguo Ji; Hiroto Kuwabara; Tao Li; Hayden T Ravert; Ursula Scheffel; Michael R Schrimpf; Heather Valentine; Dean F Wong; William H Bunnelle; Yongjun Gao; Daniel P Holt; Robert F Dannals
Synthesis and evaluation of new radioligands [(11)C]A-833834 and [(11)C]A-752274 for positron-emission tomography of α7-nicotinic acetylcholine receptors.
Dean F Wong; James Robert Brasic; Michael Stabins; Rikki Waterhouse; Wichana Chamroonrat; Robert F Dannals; Terence G Hamill; Daniel P Holt; Jongho Kim; Hiroto Kuwabara; P David Mozley
18F-FPEB, a PET radiopharmaceutical for quantifying metabotropic glutamate 5 receptors: a first-in-human study of radiochemical safety, biokinetics, and radiation dosimetry.
Elise M Weerts; Dean F Wong; Xiaoqiang Xu; XIAOJU YANG; Robert F Dannals; J James Frost; Hiroto Kuwabara; Mary E McCaul; Gary S Wand
Influence of OPRM1 Asn40Asp variant (A118G) on [11C]carfentanil binding potential: preliminary findings in human subjects.

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2013: Andrew G Horti; Jianguo Ji; Hiroto Kuwabara; Tao Li; Hayden T Ravert; Ursula Scheffel; Michael R Schrimpf; Heather Valentine; Dean F Wong; William H Bunnelle; Yongjun Gao; Daniel P Holt; Robert F Dannals
Synthesis and evaluation of new radioligands [(11)C]A-833834 and [(11)C]A-752274 for positron-emission tomography of α7-nicotinic acetylcholine receptors.
Nuclear medicine and biology 2013;40(3):395-402.
2013: Dean F Wong; James Robert Brasic; Michael Stabins; Rikki Waterhouse; Wichana Chamroonrat; Robert F Dannals; Terence G Hamill; Daniel P Holt; Jongho Kim; Hiroto Kuwabara; P David Mozley
18F-FPEB, a PET radiopharmaceutical for quantifying metabotropic glutamate 5 receptors: a first-in-human study of radiochemical safety, biokinetics, and radiation dosimetry.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2013;54(3):388-96.
2013: Elise M Weerts; Dean F Wong; Xiaoqiang Xu; XIAOJU YANG; Robert F Dannals; J James Frost; Hiroto Kuwabara; Mary E McCaul; Gary S Wand
Influence of OPRM1 Asn40Asp variant (A118G) on [11C]carfentanil binding potential: preliminary findings in human subjects.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2013;16(1):47-53.
2013: Christopher J Earley; Charlene E Gamaldo; Hiroto Kuwabara; Hayden T Ravert; Rachel Salas; Dean F Wong; James R Brašić; Robert F Dannals; Richard Allen
Increased synaptic dopamine in the putamen in restless legs syndrome.
Sleep 2013;36(1):51-7.
2013: Gary S Wand; Elise M Weerts; Dean F Wong; Xiaoqiang Xu; Hiroto Kuwabara; Mary E McCaul
The relationship between naloxone-induced cortisol and delta opioid receptor availability in mesolimbic structures is disrupted in alcohol-dependent subjects.
Addiction biology 2013;18(1):181-92.
2012: Gary S Wand; Elise M Weerts; Dean F Wong; Xiaoqiang Xu; Hiroto Kuwabara; Mary E McCaul
The relationship between naloxone-induced cortisol and mu opioid receptor availability in mesolimbic structures is disrupted in alcohol dependent subjects.
Alcohol (Fayetteville, N.Y.) 2012;46(6):511-7.
2012: Hiroto Kuwabara; Mary E McCaul; Gary S Wand; Elise M Weerts; Richard Allen; Robert F Dannals; Christopher J Earley; Dean F Wong
Dissociative changes in the Bmax and KD of dopamine D2/D3 receptors with aging observed in functional subdivisions of the striatum: a revisit with an improved data analysis method.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2012;53(5):805-12.
2012: T Otowa; T Shimada; E Shimizu; T Someya; N Sugaya; H Tanii; M Tochigi; K Tokunaga; T Umekage; S Yasuda; E Yoshida; T Yoshikawa; J Akiyoshi; K Inoue; H Kaiya; C Kakiuchi; K Kasai; N Kato; T Kato; Y Kawamura; A Koike; Y Konishi; Hiroto Kuwabara; R Kuwano; X Liu; T Miyagawa; A Miyashita; N Nishida; F Nishimura; Y Nishimura; Y Okazaki; T Sasaki
Meta-analysis of genome-wide association studies for panic disorder in the Japanese population.
Translational psychiatry 2012;2():e186.
2012: Y Aoki; W Gonoi; H Inoue; N Iwashiro; K Kasai; N Kato; M Katsura; Y Kawakubo; Akira Kunimatsu; Hiroto Kuwabara; H Matsuzaki; M Murakami; T Natsubori; Y Nippashi; H Sasaki; Y Takano; H Takao; K J Tsuchiya; Noriaki Yahata; Osamu Abe; Hidenori Yamasue
Absence of age-related prefrontal NAA change in adults with autism spectrum disorders.
Translational psychiatry 2012;2():e178.
2012: Hiroto Kuwabara; Hayden T Ravert; Daniel P Holt; Dean F Wong; Yongjun Gao; Heather Valentine; Robert F Dannals; Andrew G Horti
PET Imaging of nicotinic acetylcholine receptors in baboons with 18F-AZAN, a radioligand with improved brain kinetics.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2012;53(1):121-9.
2012: Ka Kit Wong; Hiroto Kuwabara; Martijn L T M Müller; Stephanie A Studenski; Nicolaas I Bohnen
Gender differences in nigrostriatal dopaminergic innervation are present at young-to-middle but not at older age in normal adults.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2012;19(1):183-4.
2011: Elise M Weerts; Cynthia A Munro; J James Frost; Robert F Dannals; Gary S Wand; John Hilton; Hiroto Kuwabara; Mary E McCaul
Positron emission tomography imaging of mu- and delta-opioid receptor binding in alcohol-dependent and healthy control subjects.
Alcoholism, clinical and experimental research 2011;35(12):2162-73.
2011: Gary S Wand; Elise M Weerts; Xiaoqiang Xu; J James Frost; Hiroto Kuwabara; Mary E McCaul
Naloxone-induced cortisol predicts mu opioid receptor binding potential in specific brain regions of healthy subjects.
Psychoneuroendocrinology 2011;36(10):1453-9.
2011: Christopher J Earley; Hiroto Kuwabara; Dean F Wong; Charlene E Gamaldo; Rachel Salas; James Robert Brasic; Hayden T Ravert; Robert F Dannals; Richard Allen
The dopamine transporter is decreased in the striatum of subjects with restless legs syndrome.
Sleep 2011;34(3):341-7.
2010: Ka Kit Wong; Martijn LTM Muller; Hiroto Kuwabara; Stephanie A Studenski; Nicolaas I Bohnen
Olfactory loss and nigrostriatal dopaminergic denervation in the elderly.
Neuroscience letters 2010;484(3):163-7.
2010: Udi E Ghitza; Kenzie L. Preston; David H Epstein; Hiroto Kuwabara; Christopher J Endres; badreddine bencherif; Susan J Boyd; Marc L Copersino; J James Frost; David A Gorelick
Brain mu-opioid receptor binding predicts treatment outcome in cocaine-abusing outpatients.
Biological psychiatry 2010;68(8):697-703.
2010: Dean F Wong; Hiroto Kuwabara; Andrew G Horti; Vanessa Raymont; James Robert Brasic; Maria Guevara; Weiguo Ye; Robert F Dannals; Hayden T Ravert; Ayon Nandi; Arman Rahmim; Jeffrey E Ming; Igor Grachev; Christine Roy; Nicola G Cascella
Quantification of cerebral cannabinoid receptors subtype 1 (CB1) in healthy subjects and schizophrenia by the novel PET radioligand [11C]OMAR.
NeuroImage 2010;52(4):1505-13.
2010: JING TANG; Hiroto Kuwabara; Dean F Wong; Arman Rahmim
Direct 4D reconstruction of parametric images incorporating anato-functional joint entropy.
Physics in medicine and biology 2010;55(15):4261-72.
2010: Neilly Buckalew; Marc W Haut; Howard J Aizenstein; Lisa A Morrow; Subashan Perera; Hiroto Kuwabara; Debra K Weiner
Differences in brain structure and function in older adults with self-reported disabling and nondisabling chronic low back pain.
Pain medicine (Malden, Mass.) 2010;11(8):1183-97.
2010: Andrew G Horti; Yongjun Gao; Hiroto Kuwabara; Robert F Dannals
Development of radioligands with optimized imaging properties for quantification of nicotinic acetylcholine receptors by positron emission tomography.
Life sciences 2010;86(15-16):575-84.
2009: Yongjun Gao; Hayden T Ravert; Hiroto Kuwabara; Yingxian Xiao; Christopher J Endres; John Hilton; Daniel P Holt; Anil Kumar; Mohab Alexander; Dean F Wong; Robert F Dannals; Andrew G Horti
Synthesis and biological evaluation of novel carbon-11 labeled pyridyl ethers: candidate ligands for in vivo imaging of alpha4beta2 nicotinic acetylcholine receptors (alpha4beta2-nAChRs) in the brain with positron emission tomography.
Bioorganic & medicinal chemistry 2009;17(13):4367-77.
2009: Nicolaas I Bohnen; M L T M Müller; Hiroto Kuwabara; G M Constantine; S A Studenski
Age-associated leukoaraiosis and cortical cholinergic deafferentation.
Neurology 2009;72(16):1411-6.
2009: Nicolaas I Bohnen; Martijn LTM Muller; Hiroto Kuwabara; Rakié Cham; Gregory M Constantine; Stephanie A Studenski
Age-associated striatal dopaminergic denervation and falls in community-dwelling subjects.
Journal of rehabilitation research and development 2009;46(8):1045-52.
2008: Yongjun Gao; Andrew G Horti; Hiroto Kuwabara; Hayden T Ravert; Daniel P Holt; Anil Kumar; Mohab Alexander; Dean F Wong; Robert F Dannals
New synthesis and evaluation of enantiomers of 7-methyl-2-exo-(3'-iodo-5'-pyridinyl)-7-azabicyclo[2.2.1]heptane as stereoselective ligands for PET imaging of nicotinic acetylcholine receptors.
Bioorganic & medicinal chemistry letters 2008;18(23):6168-70.
2008: Yongjun Gao; Hiroto Kuwabara; Charles E Spivak; Yingxian Xiao; Kenneth Kellar; Hayden T Ravert; Anil Kumar; Mohab Alexander; John Hilton; Dean F Wong; Robert F Dannals; Andrew G Horti
Discovery of (-)-7-methyl-2-exo-[3'-(6-[18F]fluoropyridin-2-yl)-5'-pyridinyl]-7-azabicyclo[2.2.1]heptane, a radiolabeled antagonist for cerebral nicotinic acetylcholine receptor (alpha4beta2-nAChR) with optimal positron emission tomography imaging properties.
Journal of medicinal chemistry 2008;51(15):4751-64.
2008: Dean F Wong; James Robert Brasic; Harvey S Singer; David J Schretlen; Hiroto Kuwabara; Yun Zhou; Ayon Nandi; Marika A Maris; Mohab Alexander; Weiguo Ye; Olivier Rousset; Anil Kumar; Zsolt Szabo; Albert Gjedde; Anthony A Grace
Mechanisms of dopaminergic and serotonergic neurotransmission in Tourette syndrome: clues from an in vivo neurochemistry study with PET.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2008;33(6):1239-51.
2008: Ming-Kai Chen; Hiroto Kuwabara; Yun Zhou; Robert J Adams; James Robert Brasic; Jennifer McGlothan; Tatyana Verina; Neal C Burton; Mohab Alexander; Anil Kumar; Dean F Wong; Tomás R Guilarte
VMAT2 and dopamine neuron loss in a primate model of Parkinson's disease.
Journal of neurochemistry 2008;105(1):78-90.
2008: Jame Abraham; Marc W Haut; Maria T Moran; Shannon Filburn; Susan Lemiuex; Hiroto Kuwabara
Adjuvant chemotherapy for breast cancer: effects on cerebral white matter seen in diffusion tensor imaging.
Clinical breast cancer 2008;8(1):88-91.
2008: Una D McCann; Hiroto Kuwabara; Anil Kumar; Michael Palermo; Rubyna Abbey; James Robert Brasic; Weiguo Ye; Mohab Alexander; Robert F Dannals; Dean F Wong; George A Ricaurte
Persistent cognitive and dopamine transporter deficits in abstinent methamphetamine users.
Synapse (New York, N.Y.) 2008;62(2):91-100.
2007: Gary S Wand; Lynn Marie Oswald; Mary E McCaul; Dean F Wong; ELIZABETH COLANTUONI; Yun Zhou; Hiroto Kuwabara; Anil Kumar
Association of amphetamine-induced striatal dopamine release and cortisol responses to psychological stress.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(11):2310-20.
2007: Nicolaas I Bohnen; Hiroto Kuwabara; Gregory M Constantine; Chester A Mathis; Robert Y Moore
Grooved pegboard test as a biomarker of nigrostriatal denervation in Parkinson's disease.
Neuroscience letters 2007;424(3):185-9.
2007: Yongjun Gao; Andrew G Horti; Hiroto Kuwabara; Hayden T Ravert; John Hilton; Daniel P Holt; Anil Kumar; Mohab Alexander; Christopher J Endres; Dean F Wong; Robert F Dannals
Derivatives of (-)-7-methyl-2-(5-(pyridinyl)pyridin-3-yl)-7-azabicyclo[2.2.1]heptane are potential ligands for positron emission tomography imaging of extrathalamic nicotinic acetylcholine receptors.
Journal of medicinal chemistry 2007;50(16):3814-24.
2007: Lynn Marie Oswald; Dean F Wong; Yun Zhou; Anil Kumar; James Robert Brasic; Mohab Alexander; Weiguo Ye; Hiroto Kuwabara; John Hilton; Gary S Wand
Impulsivity and chronic stress are associated with amphetamine-induced striatal dopamine release.
NeuroImage 2007;36(1):153-66.
2007: Nicolaas I Bohnen; Satyanarayana Gedela; Hiroto Kuwabara; Gregory M Constantine; Chester A Mathis; Stephanie Studenski; Robert Y Moore
Selective hyposmia and nigrostriatal dopaminergic denervation in Parkinson's disease.
Journal of neurology 2007;254(1):84-90.
2007: Edwin M Nemoto; Howard Yonas; Ronda R Pindzola; Hiroto Kuwabara; Donald Sashin; Yuefang Chang; Tudor Jovin
PET OEF reactivity for hemodynamic compromise in occlusive vascular disease.
Journal of neuroimaging : official journal of the American Society of Neuroimaging 2007;17(1):54-60.
2006: Dean F Wong; Hiroto Kuwabara; David J Schretlen; Katherine R Bonson; Yun Zhou; Ayon Nandi; James Robert Brasic; Alane S Kimes; Marika A Maris; Anil Kumar; Carlo Contoreggi; Jonathan M Links; Monique Ernst; Olivier Rousset; Stephen R Zukin; Anthony A Grace; Jae Sung Lee; Charles Rohde; Donald R Jasinski; Albert Gjedde; Edythe D London
Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(12):2716-27.
2006: Miriam Z Mintzer; Hiroto Kuwabara; Mohab Alexander; James Robert Brasic; Weiguo Ye; Monique Ernst; Roland R Griffiths; Dean F Wong
Dose effects of triazolam on brain activity during episodic memory encoding: a PET study.
Psychopharmacology 2006;188(4):445-61.
2006: Andrew G Horti; Hong Fan; Hiroto Kuwabara; John Hilton; Hayden T Ravert; Daniel P Holt; Mohab Alexander; Anil Kumar; Arman Rahmim; Ursula Scheffel; Dean F Wong; Robert F Dannals
11C-JHU75528: a radiotracer for PET imaging of CB1 cannabinoid receptors.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(10):1689-96.
2006: Cynthia A Munro; Mary E McCaul; Lynn Marie Oswald; Dean F Wong; Yun Zhou; James Robert Brasic; Hiroto Kuwabara; Anil Kumar; Mohab Alexander; Weiguo Ye; Gary S Wand
Striatal dopamine release and family history of alcoholism.
Alcoholism, clinical and experimental research 2006;30(7):1143-51.
2006: Marc W Haut; Hiroto Kuwabara; Alan M Ducatman; Ginger Hatfield; Michael W Parsons; Allene Scott; Elizabeth Parsons; Lisa A Morrow
Corpus callosum volume in railroad workers with chronic exposure to solvents.
Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine 2006;48(6):615-24.
2006: Cynthia A Munro; Mary E McCaul; Dean F Wong; Lynn Marie Oswald; Yun Zhou; James Robert Brasic; Hiroto Kuwabara; Anil Kumar; Mohab Alexander; Weiguo Ye; Gary S Wand
Sex differences in striatal dopamine release in healthy adults.
Biological psychiatry 2006;59(10):966-74.
2006: Ronda R Pindzola; Donald Sashin; Edwin M Nemoto; Hiroto Kuwabara; John W Wilson; Howard Yonas
Identifying regions of compromised hemodynamics in symptomatic carotid occlusion by cerebrovascular reactivity and oxygen extraction fraction.
Neurological research 2006;28(2):149-54.
2006: Edwin M Nemoto; Gutti Rao; Timothy Robinson; Todd Saunders; John Kirkman; Denise Davis; Hiroto Kuwabara; C Edward Dixon
Effect of local cooling (15 degrees C for 24 hours) with the Chillerpad after traumatic brain injury in the nonhuman primate.
Advances in experimental medicine and biology 2006;578():311-5.
2005: Lynn Marie Oswald; Dean F Wong; Mary E McCaul; Yun Zhou; Hiroto Kuwabara; Leena Choi; James Robert Brasic; Gary S Wand
Relationships among ventral striatal dopamine release, cortisol secretion, and subjective responses to amphetamine.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(4):821-32.
2005: Edwin M Nemoto; Howard Yonas; Hiroto Kuwabara; Ronda R Pindzola; Donald Sashin; Yuefang Chang; Tudor Jovin; James Gebel; Maxim D Hammer; Lawrence R Wechsler
Differentiating hemodynamic compromise by the OEF response to acetazolamide in occlusive vascular disease.
Advances in experimental medicine and biology 2005;566():135-41.
2005: Edwin M Nemoto; Charles A Jungreis; Donald Larnard; Hiroto Kuwabara; Michael Horowitz; Amin Kassam
Hyperthermia and hypermetabolism in focal cerebral ischemia.
Advances in experimental medicine and biology 2005;566():83-9.
2004: Edwin M Nemoto; Howard Yonas; Hiroto Kuwabara; Ronda R Pindzola; Donald Sashin; Carolyn Meltzer; Julie C Price; Yuefang Chang; David W Johnson
Identification of hemodynamic compromise by cerebrovascular reserve and oxygen extraction fraction in occlusive vascular disease.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2004;24(10):1081-9.
2004: Peter Brust; Gerd Vorwieger; Bernd Walter; Frank Füchtner; Holger Stark; Hiroto Kuwabara; Michael Herzau; Thomas Opfermann; Jörg Steinbach; Vadivel Ganapathy; Reinhard Bauer
The influx of neutral amino acids into the porcine brain during development: a positron emission tomography study.
Brain research. Developmental brain research 2004;152(2):241-53.
2004: Bernd Walter; Peter Brust; Frank Füchtner; Marco Müller; Rainer Hinz; Hiroto Kuwabara; Harald Fritz; Ulrich Zwiener; Reinhard Bauer
Age-dependent effects of severe traumatic brain injury on cerebral dopaminergic activity in newborn and juvenile pigs.
Journal of neurotrauma 2004;21(8):1076-89.
2004: Amin Kassam; Edwin M Nemoto; Jeffrey Balzer; Gutti Rao; William C Welch; Hiroto Kuwabara; Fernando E Boada; Michael Horowitz
Effects of Tisseel fibrin glue on the central nervous system of nonhuman primates.
Ear, nose, & throat journal 2004;83(4):246-8, 250, 252 passim.
2003: Peter Brust; Rainer Hinz; Hiroto Kuwabara; Swen Hesse; Jörg Zessin; Beate Pawelke; H Stephan; Ralf Bergmann; Jörg Steinbach; Osama Sabri
In vivo measurement of the serotonin transporter with (S)-([18F]fluoromethyl)-(+)-McN5652.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(11):2010-9.
2003: Peter Brust; Jörg Zessin; Hiroto Kuwabara; Beate Pawelke; Marion Kretzschmar; Rainer Hinz; Jörgen Bergman; Olli Eskola; Olof Solin; Jörg Steinbach; Bernd Johannsen
Positron emission tomography imaging of the serotonin transporter in the pig brain using [11C](+)-McN5652 and S-([18F]fluoromethyl)-(+)-McN5652.
Synapse (New York, N.Y.) 2003;47(2):143-51.
2002: W Andrew Kofke; Ahmed F Attaallah; Hiroto Kuwabara; Robert H Garman; Elizabeth H Sinz; John Barbaccia; Naresh Gupta; Jeffery P Hogg
The neuropathologic effects in rats and neurometabolic effects in humans of large-dose remifentanil.
Anesthesia and analgesia 2002;94(5):1229-36, table of contents.
2001: Marc W Haut; R G Arias; M T Moran; S Leach; Michael W Parsons; Hiroto Kuwabara
Neural activation during frequency-memory performance.
Neuropsychology 2001;15(4):568-75.
2001: Sadahiko Nishizawa; Hiroto Kuwabara; Makoto Ueno; T Shimono; Hiroshi Toyoda; Junji Konishi
Double-injection FDG method to measure cerebral glucose metabolism twice in a single procedure.
Annals of nuclear medicine 2001;15(3):203-7.
2001: Kenji Kanenishi; Hiroto Kuwabara; M Ueno; C Sato; H Sakamoto; Toshiyuki Hata
Change of adrenomedullin concentrations in plasma and amniotic fluid, and human placental adrenomedullin expression with advancing gestation.
Placenta 2001;22(2-3):244-50.
2000: Marc W Haut; S Leach; Hiroto Kuwabara; S Whyte; T Callahan; Alan M Ducatman; L J Lombardo; N Gupta
Verbal working memory and solvent exposure: a positron emission tomography study.
Neuropsychology 2000;14(4):551-8.
2000: Olivier Rousset; P Deep; Hiroto Kuwabara; A C Evans; Albert Gjedde; Paul Cumming
Effect of partial volume correction on estimates of the influx and cerebral metabolism of 6-[(18)F]fluoro-L-dopa studied with PET in normal control and Parkinson's disease subjects.
Synapse (New York, N.Y.) 2000;37(2):81-9.
2000: Hiroto Kuwabara
Regional cerebral blood flow and metabolism in chronic subdural hematoma.
Neurosurgery clinics of North America 2000;11(3):499-502.
2000: Kenji Kanenishi; Hiroto Kuwabara; M Ueno; H Sakamoto; Toshiyuki Hata
Immunohistochemical adrenomedullin expression is decreased in the placenta from pregnancies with pre-eclampsia.
Pathology international 2000;50(7):536-40.
2000: Kazutaka Dohmoto; Jiro Fujita; Yuji Ohtsuki; N Kotsuna; H Mitsunaka; Hiroto Kuwabara; Jiro Takahara
Synchronous four primary lung adenocarcinoma associated with multiple atypical adenomatous hyperplasia.
Lung cancer (Amsterdam, Netherlands) 2000;27(2):125-30.
2000: Marc W Haut; Hiroto Kuwabara; S Leach; R G Arias
Neural activation during performance of number-letter sequencing.
Applied neuropsychology 2000;7(4):237-42.
1999: Hiroto Kuwabara; M Ohno; S Moriwaki
Uterine adenomyoma of endocervical type.
Pathology international 1999;49(11):1019-21.
1999: Fuminori Goda; K Matsushita; Hiroto Kuwabara; Hisashi Usuki; Takashi Maeba; Hajime Maeta
Recurrent mesenteric desmoid tumors with multiple peritoneal dissemination: a case report and review of desmoid in Japan.
Hepato-gastroenterology 1999;46(29):2891-3.
1999: H Fujita; Hiroto Kuwabara; David C Reutens; Albert Gjedde
Oxygen consumption of cerebral cortex fails to increase during continued vibrotactile stimulation.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1999;19(3):266-71.
1999: Hiroto Kuwabara; M Nagai; Genji Yamaoka; H Ohnishi; K Kawakami
Specific skin manifestations in CD56 positive acute myeloid leukemia.
Journal of cutaneous pathology 1999;26(1):1-5.
1998: Gabriel Léger; Albert Gjedde; Hiroto Kuwabara; M Guttman; Paul Cumming
Effect of catechol-O-methyltransferase inhibition on brain uptake of [18F]fluorodopa: implications for compartmental modelling and clinical usefulness.
Synapse (New York, N.Y.) 1998;30(4):351-61.
1998: O Mitomo; S Aoki; T Tsunoda; M Yamaguchi; Hiroto Kuwabara
Quantitative analysis of nonuniform distributions in lung perfusion scintigraphy.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1998;39(9):1630-5.
1998: Hiroto Kuwabara; M Yamane; S Okada
Secretory breast carcinoma in a 66 year old man.
Journal of clinical pathology 1998;51(7):545-7.
1998: Paul Cumming; Ariel R Ase; Hiroto Kuwabara; Albert Gjedde
[3H]DOPA formed from [3H]tyrosine in living rat brain is not committed to dopamine synthesis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1998;18(5):491-9.
1998: Hiroto Kuwabara; H Uda
Small cell carcinoma of the gall-bladder with intestinal metaplastic epithelium.
Pathology international 1998;48(4):303-6.
1997: P Deep; Hiroto Kuwabara; Albert Gjedde; Paul Cumming
The kinetic behaviour of [3H]DOPA in living rat brain investigated by compartmental modelling of static autoradiograms.
Journal of neuroscience methods 1997;78(1-2):157-68.
1997: Paul Cumming; Ariel R Ase; C Laliberté; Hiroto Kuwabara; Albert Gjedde
In vivo regulation of DOPA decarboxylase by dopamine receptors in rat brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(11):1254-60.
1997: Hiroto Kuwabara; H Uda
Clear cell mammary malignant myoepithelioma with abundant glycogens.
Journal of clinical pathology 1997;50(8):700-2.
1997: Hiroto Kuwabara; J Takeda
Malignant melanoma of the lacrimal sac with surrounding melanosis.
Archives of pathology & laboratory medicine 1997;121(5):517-9.
1997: H Fujita; E Meyer; David C Reutens; Hiroto Kuwabara; A C Evans; Albert Gjedde
Cerebral [15O] water clearance in humans determined by positron emission tomography: II. Vascular responses to vibrotactile stimulation.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(1):73-9.
1996: Hiroto Kuwabara; H Uda
Adult T cell leukemia presenting as multiple submucosal tumors of the intestine: detection of HTLV-I DNA by polymerase chain reaction.
The Kobe journal of medical sciences 1996;42(5):325-32.
1996: Hiroto Kuwabara; S Tanaka; H Sakamoto; M Oryu; H Uda
Antibody mediated ligation of platelet/endothelial cell adhesion molecule-1 (PECAM-1) on neutrophils enhances adhesion to cultured human dermal microvascular endothelial cells.
The Kobe journal of medical sciences 1996;42(4):233-41.
1996: K Murase; Hiroto Kuwabara; Y Yasuhara; A C Evans; Albert Gjedde
Mapping of change in cerebral glucose utilization using fluorine-18 fluorodeoxyglucose double injection and the constrained weighted-integration method.
IEEE transactions on medical imaging 1996;15(6):824-35.
1995: Paul Cumming; Ariel R Ase; Mirko Diksic; J Harrison; D Jolly; Hiroto Kuwabara; C Laliberté; Albert Gjedde
Metabolism and blood-brain clearance of L-3,4-dihydroxy-[3H]phenylalanine ([3H]DOPA) and 6-[18F]fluoro-L-DOPA in the rat.
Biochemical pharmacology 1995;50(7):943-6.
1995: Paul Cumming; Hiroto Kuwabara; Ariel R Ase; Albert Gjedde
Regulation of DOPA decarboxylase activity in brain of living rat.
Journal of neurochemistry 1995;65(3):1381-90.
1995: Hiroto Kuwabara; Paul Cumming; Y Yasuhara; Gabriel Léger; M Guttman; Mirko Diksic; Alan C Evans; Albert Gjedde
Regional striatal DOPA transport and decarboxylase activity in Parkinson's disease.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995;36(7):1226-31.
1995: K Sogawa; T Yamada; S Oka; K Kawasaki; S Mori; H Tanaka; H Norimatsu; Y Cai; Hiroto Kuwabara; H Shima
Enhanced expression of catalytic subunit isoform PP1 gamma 1 of protein phosphatase type 1 associated with malignancy of osteogenic tumor.
Cancer letters 1995;89(1):1-6.
1994: J Reith; C Benkelfat; A Sherwin; Y Yasuhara; Hiroto Kuwabara; Frederick Andermann; S Bachneff; Paul Cumming; Mirko Diksic; S E Dyve; P Etienne; Alan C Evans; S Lal; M Shevell; G Savard; Dean F Wong; G Chouinard; Albert Gjedde
Elevated dopa decarboxylase activity in living brain of patients with psychosis.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(24):11651-4.
1994: Paul Cumming; Hiroto Kuwabara; Albert Gjedde
A kinetic analysis of 6-[18F]fluoro-L-dihydroxyphenylalanine metabolism in the rat.
Journal of neurochemistry 1994;63(5):1675-82.
1994: Hiroto Kuwabara; K Saito; T Shibanushi; T Kawahara
Malignant fibrous histiocytoma of the larynx.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 1994;251(3):178-82.
1993: Albert Gjedde; Gabriel Léger; Paul Cumming; Y Yasuhara; Alan C Evans; M Guttman; Hiroto Kuwabara
Striatal L-dopa decarboxylase activity in Parkinson's disease in vivo: implications for the regulation of dopamine synthesis.
Journal of neurochemistry 1993;61(4):1538-41.
1993: M Guttman; Gabriel Léger; A Reches; A Evans; Hiroto Kuwabara; Jesse Cedarbaum; Albert Gjedde
Administration of the new COMT inhibitor OR-611 increases striatal uptake of fluorodopa.
Movement disorders : official journal of the Movement Disorder Society 1993;8(3):298-304.
1993: Paul Cumming; Gabriel Léger; Hiroto Kuwabara; Albert Gjedde
Pharmacokinetics of plasma 6-[18F]fluoro-L-3,4-dihydroxyphenylalanine ([18F]Fdopa) in humans.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(4):668-75.
1993: H Hoshi; Hiroto Kuwabara; Gabriel Léger; Paul Cumming; M Guttman; Albert Gjedde
6-[18F]fluoro-L-dopa metabolism in living human brain: a comparison of six analytical methods.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(1):57-69.
1993: Hiroto Kuwabara; Paul Cumming; J Reith; Gabriel Léger; Mirko Diksic; Alan C Evans; Albert Gjedde
Human striatal L-dopa decarboxylase activity estimated in vivo using 6-[18F]fluoro-dopa and positron emission tomography: error analysis and application to normal subjects.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(1):43-56.
1993: Albert Gjedde; Hiroto Kuwabara
Absent recruitment of capillaries in brain tissue recovering from stroke.
Acta neurochirurgica. Supplementum 1993;57():35-40.
1992: Hiroto Kuwabara; S Ohta; Peter Brust; E Meyer; Albert Gjedde
Density of perfused capillaries in living human brain during functional activation.
Progress in brain research 1992;91():209-15.
1991: Hiroto Kuwabara; Albert Gjedde
Measurements of glucose phosphorylation with FDG and PET are not reduced by dephosphorylation of FDG-6-phosphate.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1991;32(4):692-8.
1991: Albert Gjedde; J Reith; S Dyve; Gabriel Léger; M Guttman; Mirko Diksic; A Evans; Hiroto Kuwabara
Dopa decarboxylase activity of the living human brain.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(7):2721-5.
1991: Hiroto Kuwabara; H Uda; K Saito; T Maruyama; S Tanaka
Dendritic cells in the murine dermis in delayed-type contact hypersensitivity. An ultrastructural and immunocytochemical study.
Acta pathologica japonica 1991;41(2):106-12.
1990: J Reith; S Dyve; Hiroto Kuwabara; M Guttman; Mirko Diksic; Albert Gjedde
Blood-brain transfer and metabolism of 6-[18F]fluoro-L-dopa in rat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1990;10(5):707-19.
1990: Albert Gjedde; Hiroto Kuwabara; Antoine M Hakim
Reduction of functional capillary density in human brain after stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1990;10(3):317-26.
1990: Hiroto Kuwabara; Alan C Evans; Albert Gjedde
Michaelis-Menten constraints improved cerebral glucose metabolism and regional lumped constant measurements with [18F]fluorodeoxyglucose.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1990;10(2):180-9.
1990: Albert Gjedde; Hiroto Kuwabara; A C Evans
Metabolic brain imaging. Direct regional measurement of transfer coefficients and lumped constant.
Acta radiologica. Supplementum 1990;374():117-21.
1989: Antoine M Hakim; Alan C Evans; L Berger; Hiroto Kuwabara; K Worsley; G Marchal; C Biel; R Pokrupa; M Diksic; E Meyer
The effect of nimodipine on the evolution of human cerebral infarction studied by PET.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1989;9(4):523-34.