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Tsunehiko Kuzuya

Research Profile

Anatomy

Disorders

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Physiology

Chemicals & Drugs

Procedures

Myocardial Ischemic Preconditioning

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Yulin Liao; Fuminobu Ishikura; Shintaro Beppu; Masanori Asakura; Seiji Takashima; Hiroshi Asanuma; Shoji Sanada; Jiyoon Kim; Hisakazu Ogita; Tsunehiko Kuzuya; Koichi Node; Masafumi Kitakaze; Masatsugu Hori
Echocardiographic assessment of LV hypertrophy and function in aortic-banded mice: necropsy validation.
Issei Shiotani; Hiroshi Sato; Hideyuki Sato; Hiroshi Yokoyama; Yozo Ohnishi; Eiji Hishida; Kunihiro Kinjo; Daisaku Nakatani; Tsunehiko Kuzuya; Masatsugu Hori
Muscle pump-dependent self-perfusion mechanism in legs in normal subjects and patients with heart failure.
Keiko Ono; Tohru Masuyama; Kazuhiro Yamamoto; Reiko Doi; Yasushi Sakata; Nagahiro Nishikawa; Toshiaki Mano; Tsunehiko Kuzuya; Hiroshi Takeda; Masatsugu Hori
Echo doppler assessment of left ventricular function in rats with hypertensive hypertrophy.

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2002: Yulin Liao; Fuminobu Ishikura; Shintaro Beppu; Masanori Asakura; Seiji Takashima; Hiroshi Asanuma; Shoji Sanada; Jiyoon Kim; Hisakazu Ogita; Tsunehiko Kuzuya; Koichi Node; Masafumi Kitakaze; Masatsugu Hori
Echocardiographic assessment of LV hypertrophy and function in aortic-banded mice: necropsy validation.
American journal of physiology. Heart and circulatory physiology 2002;282(5):H1703-8.
2002: Issei Shiotani; Hiroshi Sato; Hideyuki Sato; Hiroshi Yokoyama; Yozo Ohnishi; Eiji Hishida; Kunihiro Kinjo; Daisaku Nakatani; Tsunehiko Kuzuya; Masatsugu Hori
Muscle pump-dependent self-perfusion mechanism in legs in normal subjects and patients with heart failure.
Journal of applied physiology (Bethesda, Md. : 1985) 2002;92(4):1647-54.
2002: Keiko Ono; Tohru Masuyama; Kazuhiro Yamamoto; Reiko Doi; Yasushi Sakata; Nagahiro Nishikawa; Toshiaki Mano; Tsunehiko Kuzuya; Hiroshi Takeda; Masatsugu Hori
Echo doppler assessment of left ventricular function in rats with hypertensive hypertrophy.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2002;15(2):109-17.
2001: Yasushi Sakata; Kazuhiro Yamamoto; Tohru Masuyama; Toshiaki Mano; Nagahiro Nishikawa; Tsunehiko Kuzuya; Takeshi Miwa; Masatsugu Hori
Ventricular production of natriuretic peptides and ventricular structural remodeling in hypertensive heart failure.
Journal of hypertension 2001;19(10):1905-12.
2001: Hiroshi Asanuma; Masafumi Kitakaze; Hiroharu Funaya; S Takashima; Tetsuo Minamino; Koichi Node; Y Sakata; Masanori Asakura; Shoji Sanada; Yoshiro Shinozaki; Hidezo Mori; Tsunehiko Kuzuya; M Tada; Masatsugu Hori
Nifedipine limits infarct size via NO-dependent mechanisms in dogs.
Basic research in cardiology 2001;96(5):497-505.
2001: Shoji Sanada; Masafumi Kitakaze; Koichi Node; Seiji Takashima; Akiko Ogai; Hiroshi Asanuma; Yasushi Sakata; Masanori Asakura; Hisakazu Ogita; Yulin Liao; T Fukushima; J Yamada; Tetsuo Minamino; Tsunehiko Kuzuya; Masatsugu Hori
Differential subcellular actions of ACE inhibitors and AT(1) receptor antagonists on cardiac remodeling induced by chronic inhibition of NO synthesis in rats.
Hypertension 2001;38(3):404-11.
2001: Masafumi Kitakaze; Koichi Node; Seiji Takashima; Hiroshi Asanuma; Masanori Asakura; Shoji Sanada; Yoshiro Shinozaki; Hidezo Mori; H Sato; Tsunehiko Kuzuya; Masatsugu Hori
Role of cellular acidosis in production of nitric oxide in canine ischemic myocardium.
Journal of molecular and cellular cardiology 2001;33(9):1727-37.
2001: Shoji Sanada; Masafumi Kitakaze; PJ Papst; Hiroshi Asanuma; Koichi Node; Seiji Takashima; Masanori Asakura; Hisakazu Ogita; Yulin Liao; Yasushi Sakata; Akiko Ogai; Tomi Fukushima; J Yamada; Yoshiro Shinozaki; Tsunehiko Kuzuya; Hidezo Mori; N Terada; Masatsugu Hori
Cardioprotective effect afforded by transient exposure to phosphodiesterase III inhibitors: the role of protein kinase A and p38 mitogen-activated protein kinase.
Circulation 2001;104(6):705-10.
2001: Yasunori Shintani; Hiroshi Ito; Katsuomi Iwakura; K Sugimoto; Koichi Yamamoto; Tohru Masuyama; Tsunehiko Kuzuya; Masatsugu Hori; Yorihiko Higashino; Kenshi Fujii
Prediction of wall motion recovery from the left anterior descending coronary artery velocity pattern recorded by transthoracic doppler echocardiography in patients with anterior wall myocardial infarction retrospective and prospective studies.
Japanese circulation journal 2001;65(8):717-22.
2001: Kunihiro Kinjo; Hiroshi Sato; H Sato; Issei Shiotani; Toshiya Kurotobi; Yozo Ohnishi; Eiji Hishida; Daisaku Nakatani; Hiroshi Ito; Yukihiro Koretsune; Atsushi Hirayama; Jun Tanouchi; Masayoshi Mishima; Tsunehiko Kuzuya; Hiroshi Takeda; Masatsugu Hori
Circadian variation of the onset of acute myocardial infarction in the Osaka area, 1998-1999: characterization of morning and nighttime peaks.
Japanese circulation journal 2001;65(7):617-20.
2001: Yasushi Matsumura; E Saeki; Kinya Otsu; T Morita; H Takeda; Tsunehiko Kuzuya; Masatsugu Hori; Hideo Kusuoka
Intracellular calcium level required for calpain activation in a single myocardial cell.
Journal of molecular and cellular cardiology 2001;33(6):1133-42.
2001: Masafumi Kitakaze; Masanori Asakura; Yasushi Sakata; Hiroshi Asanuma; Shoji Sanada; Tsunehiko Kuzuya; J Miyazaki; Seiji Takashima; Masatsugu Hori
cDNA array hybridization reveals cardiac gene expression in acute ischemic murine hearts.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2001;15(2):125-30.
2001: Shoji Sanada; Masafumi Kitakaze; PJ Papst; K Hatanaka; Hiroshi Asanuma; T Aki; Yoshiro Shinozaki; Hisakazu Ogita; Koichi Node; Seiji Takashima; Masanori Asakura; J Yamada; Tomi Fukushima; Akiko Ogai; Tsunehiko Kuzuya; Hidezo Mori; N Terada; Kenji Yoshida; Masatsugu Hori
Role of phasic dynamism of p38 mitogen-activated protein kinase activation in ischemic preconditioning of the canine heart.
Circulation research 2001;88(2):175-80.
2001: Toshihiko Toyofuku; Y Akamatsu; H Zhang; Tsunehiko Kuzuya; M Tada; Masatsugu Hori
c-Src regulates the interaction between connexin-43 and ZO-1 in cardiac myocytes.
The Journal of biological chemistry 2001;276(3):1780-8.
2001: Hiroshi Asanuma; Masafumi Kitakaze; Koichi Node; Seiji Takashima; Yasushi Sakata; Masanori Asakura; Shoji Sanada; Yoshiro Shinozaki; Hidezo Mori; M Tada; Tsunehiko Kuzuya; Masatsugu Hori
Benidipine, a long-acting Ca channel blocker, limits infarct size via bradykinin- and NO-dependent mechanisms in canine hearts.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2001;15(3):225-31.
2001: Yasushi Sakata; Tohru Masuyama; Kazuhiro Yamamoto; Reiko Doi; Toshiaki Mano; Tsunehiko Kuzuya; Takeshi Miwa; Hiroshi Takeda; Masatsugu Hori
Renin angiotensin system-dependent hypertrophy as a contributor to heart failure in hypertensive rats: different characteristics from renin angiotensin system-independent hypertrophy.
Journal of the American College of Cardiology 2001;37(1):293-9.
2001: Shoji Sanada; Masafumi Kitakaze; Hiroshi Asanuma; K Harada; Hisakazu Ogita; Koichi Node; Seiji Takashima; Yasushi Sakata; Masanori Asakura; Yoshiro Shinozaki; Hidezo Mori; Tsunehiko Kuzuya; Masatsugu Hori
Role of mitochondrial and sarcolemmal K(ATP) channels in ischemic preconditioning of the canine heart.
American journal of physiology. Heart and circulatory physiology 2001;280(1):H256-63.
2000: Tohru Masuyama; Kazuhiro Yamamoto; Yasushi Sakata; Reiko Doi; Nagahiro Nishikawa; H Kondo; Keiko Ono; Tsunehiko Kuzuya; Motoaki Sugawara; Masatsugu Hori
Evolving changes in Doppler mitral flow velocity pattern in rats with hypertensive hypertrophy.
Journal of the American College of Cardiology 2000;36(7):2333-8.
2000: Yasushi Sakata; Tohru Masuyama; Kazuhiro Yamamoto; Nagahiro Nishikawa; H Yamamoto; H Kondo; Keiko Ono; Kinya Otsu; Tsunehiko Kuzuya; Takeshi Miwa; Hiroshi Takeda; E Miyamoto; Masatsugu Hori
Calcineurin inhibitor attenuates left ventricular hypertrophy, leading to prevention of heart failure in hypertensive rats.
Circulation 2000;102(18):2269-75.
2000: Tetsuo Minamino; Masafumi Kitakaze; PJ Papst; Y Ueda; Yasushi Sakata; Hiroshi Asanuma; Akiko Ogai; Tsunehiko Kuzuya; N Terada; Masatsugu Hori
Inhibition of nitric oxide synthesis induces coronary vascular remodeling and cardiac hypertrophy associated with the activation of p70 S6 kinase in rats.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2000;14(5):533-42.
2000: N Yamashita; Shiro Hoshida; Kinya Otsu; N Taniguchi; Tsunehiko Kuzuya; Masatsugu Hori
The involvement of cytokines in the second window of ischaemic preconditioning.
British journal of pharmacology 2000;131(3):415-22.
2000: P P Palmes; Tohru Masuyama; Kazuhiro Yamamoto; H Kondo; Yasushi Sakata; S Takiuchi; Tsunehiko Kuzuya; Masatsugu Hori
Myocardial longitudinal motion by tissue velocity imaging in the evaluation of patients with myocardial infarction.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2000;13(9):818-26.
2000: Masafumi Kitakaze; Koichi Node; Hiroshi Asanuma; Seiji Takashima; Y Sakata; Masanori Asakura; Shoji Sanada; Yoshiro Shinozaki; Hidezo Mori; Tsunehiko Kuzuya; Masatsugu Hori
Protein tyrosine kinase is not involved in the infarct size-limiting effect of ischemic preconditioning in canine hearts.
Circulation research 2000;87(4):303-8.
2000: Koichi Node; Masafumi Kitakaze; F Yoshihara; T Sasaki; Tsunehiko Kuzuya; Masatsugu Hori
Increased cardiac levels of nitric oxide in patients with chronic heart failure.
The American journal of cardiology 2000;86(4):474-7.
2000: Kazuhiro Yamamoto; Tohru Masuyama; Yasushi Sakata; Toshiaki Mano; Nagahiro Nishikawa; H Kondo; Noriyuki Akehi; Tsunehiko Kuzuya; Takeshi Miwa; Masatsugu Hori
Roles of renin-angiotensin and endothelin systems in development of diastolic heart failure in hypertensive hearts.
Cardiovascular research 2000;47(2):274-83.
2000: P P Palmes; Tohru Masuyama; Kazuhiro Yamamoto; H Kondo; Yasushi Sakata; S Takiuchi; Tsunehiko Kuzuya; Masatsugu Hori
High-frame-rate tissue harmonic imaging enhances anatomic M-mode sections of the left ventricle in short-axis view.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2000;13(8):738-47.
2000: Nobushige Yamashita; Shiro Hoshida; Kinya Otsu; Naoyuki Taniguchi; Tsunehiko Kuzuya; Masatsugu Hori
Involvement of cytokines in the mechanism of whole-body hyperthermia-induced cardioprotection.
Circulation 2000;102(4):452-7.
2000: Toshihiko Toyofuku; Z Hong; Tsunehiko Kuzuya; M Tada; Masatsugu Hori
Wnt/frizzled-2 signaling induces aggregation and adhesion among cardiac myocytes by increased cadherin-beta-catenin complex.
The Journal of cell biology 2000;150(1):225-41.
2000: Tetsuo Minamino; Masafumi Kitakaze; Y Ueda; Hiroshi Asanuma; PJ Papst; Tsunehiko Kuzuya; N Terada; Masatsugu Hori
Chronic treatment with FK506 increases p70 S6 kinase activity associated with reduced nitric oxide synthase activity in rabbit hearts.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2000;14(3):329-36.
2000: Kazuhiro Yamamoto; Tohru Masuyama; Yasushi Sakata; Reiko Doi; Keiko Ono; Toshiaki Mano; H Kondo; Tsunehiko Kuzuya; Takeshi Miwa; Masatsugu Hori
Local neurohumoral regulation in the transition to isolated diastolic heart failure in hypertensive heart disease: absence of AT1 receptor downregulation and 'overdrive' of the endothelin system.
Cardiovascular research 2000;46(3):421-32.
2000: Moto-o Date; Kinya Otsu; Kazuhiko Nishida; Toshihiko Toyofuku; Yasushi Matsumura; Takashi Morita; Shinichi Hirotani; Y Okazaki; Y Hayashizaki; V Nigro; Tsunehiko Kuzuya; Michihiko Tada; Masatsugu Hori
Single-strand conformation polymorphism analysis on the delta-sarcoglycan gene in Japanese patients with hypertrophic cardiomyopathy.
The American journal of cardiology 2000;85(11):1315-8.
2000: Masatsugu Hori; Koichi Yamamoto; K Kodama; Seiji Takashima; Hiroshi Sato; Yukihiro Koretsune; Tsunehiko Kuzuya; C Yutani; Norihide Fukushima; Shigeaki Ohtake; Ryota Shirakura; Hikaru Matsuda
Successful launch of cardiac transplantation in Japan. Osaka University Cardiac Transplant Program.
Japanese circulation journal 2000;64(5):326-32.
2000: Shiro Hoshida; N Yamashita; Tsunehiko Kuzuya; Masatsugu Hori
Differential effects of long-term renin-angiotensin system blockade on limitation of infarct size in cholesterol-fed rabbits.
Atherosclerosis 2000;149(2):287-94.
2000: Tohru Masuyama; K Yamamoto; H Kondo; N Nishikawa; Y Sakata; K Ono; Tsunehiko Kuzuya; Masatsugu Hori
[Intravenous contrast echocardiography].
Journal of cardiology 2000;35 Suppl 1():23-9.
2000: Masafumi Kitakaze; Hiroshi Asanuma; Seiji Takashima; Tetsuo Minamino; Y Ueda; Yasushi Sakata; Masanori Asakura; Shoji Sanada; Tsunehiko Kuzuya; Masatsugu Hori
Nifedipine-induced coronary vasodilation in ischemic hearts is attributable to bradykinin- and NO-dependent mechanisms in dogs.
Circulation 2000;101(3):311-7.
2000: Moto-o Date; Kinya Otsu; Tsunehiko Kuzuya; Masatsugu Hori
[Animal models of cardiomyopathy].
Nihon rinsho. Japanese journal of clinical medicine 2000;58(1):233-9.
2000: Reiko Doi; Tohru Masuyama; Kazuhiro Yamamoto; Y Doi; Toshiaki Mano; Yasushi Sakata; Keiko Ono; Tsunehiko Kuzuya; S Hirota; T Koyama; Takeshi Miwa; Masatsugu Hori
Development of different phenotypes of hypertensive heart failure: systolic versus diastolic failure in Dahl salt-sensitive rats.
Journal of hypertension 2000;18(1):111-20.
2000: Shiro Hoshida; N Yamashita; Kinya Otsu; Tsunehiko Kuzuya; Masatsugu Hori
Cholesterol feeding exacerbates myocardial injury in Zucker diabetic fatty rats.
American journal of physiology. Heart and circulatory physiology 2000;278(1):H256-62.
1999: Yoko Ueda; Masafumi Kitakaze; Kazuo Komamura; Tetsuo Minamino; Hiroshi Asanuma; Hiroshi Sato; Tsunehiko Kuzuya; Hiroshi Takeda; Masatsugu Hori
Pravastatin restored the infarct size-limiting effect of ischemic preconditioning blunted by hypercholesterolemia in the rabbit model of myocardial infarction.
Journal of the American College of Cardiology 1999;34(7):2120-5.
1999: A D Blann; F Li-Saw-Hee; Gregory Y H Lip; Tetsuo Minamino; Masafumi Kitakaze; Shoji Sanada; Hiroshi Asanuma; Toshiya Kurotobi; Yukihiro Koretsune; Masatake Fukunami; Tsunehiko Kuzuya; Noritake Hoki; Masatsugu Hori
Increased membrane and soluble P-selectin in atrial fibrillation.
Circulation 1999;100(17):e86-7.
1999: Toshihiko Toyofuku; Masanori Yabuki; Kinya Otsu; Tsunehiko Kuzuya; M Tada; Masatsugu Hori
Functional role of c-Src in gap junctions of the cardiomyopathic heart.
Circulation research 1999;85(8):672-81.
1999: Masafumi Kitakaze; Koichi Node; Kazuo Komamura; Tetsuo Minamino; H Kosaka; Tsunehiko Kuzuya; Masatsugu Hori
Intracoronary administration of adenosine triphosphate increases coronary blood flow and attenuates the severity of myocardial ischemic injury in dogs.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1999;13(5):407-14.
1999: N Yamashita; Shiro Hoshida; Kinya Otsu; N Taniguchi; Tsunehiko Kuzuya; Masatsugu Hori
Monophosphoryl lipid A provides biphasic cardioprotection against ischaemia-reperfusion injury in rat hearts.
British journal of pharmacology 1999;128(2):412-8.
1999: Masafumi Kitakaze; Seiji Takashima; Tetsuo Minamino; Koichi Node; Yoshiro Shinozaki; Hidezo Mori; Tsunehiko Kuzuya; Masatsugu Hori
Improvement by 5-amino-4-imidazole carboxamide riboside of the contractile dysfunction that follows brief periods of ischemia through increases in ecto-5-nucleotidase activity and adenosine release in canine hearts.
Japanese circulation journal 1999;63(7):542-53.
1999: Masafumi Kitakaze; Tsunehiko Kuzuya; Masatsugu Hori
[Efficacy of angiotensin II receptor antagonists as a novel drug for the treatment of chronic heart failure--in comparison with ACE inhibitors].
Nihon rinsho. Japanese journal of clinical medicine 1999;57(5):1148-57.
1999: Masafumi Kitakaze; Tetsuo Minamino; Koichi Node; Seiji Takashima; Hiroharu Funaya; Tsunehiko Kuzuya; Masatsugu Hori
Adenosine and cardioprotection in the diseased heart.
Japanese circulation journal 1999;63(4):231-43.
1999: Hiroshi Ito; Yoshiaki Taniyama; Katsuomi Iwakura; Nagahiro Nishikawa; Tohru Masuyama; Tsunehiko Kuzuya; Masatsugu Hori; Yorihiko Higashino; Kenshi Fujii; Tetsuo Minamino
Intravenous nicorandil can preserve microvascular integrity and myocardial viability in patients with reperfused anterior wall myocardial infarction.
Journal of the American College of Cardiology 1999;33(3):654-60.
1999: Tetsuo Minamino; Masafumi Kitakaze; Tsunehiko Kuzuya; Masatsugu Hori
[Increased expression of P-selectin on platelets is a risk factor for silent cerebral infarction in patients with atrial fibrillation: role of nitric oxide].
Journal of cardiology 1999;33(2):103-4.
1999: Yukihiko Ueda; Masafumi Kitakaze; M Imakita; H Ishibashi-Ueda; Tetsuo Minamino; Hiroshi Asanuma; T Ozaki; E Imamura; Tsunehiko Kuzuya; Masatsugu Hori
Glycoprotein IIb/IIIa antagonist FK633 could not prevent neointimal thickening in stent implantation model of canine coronary artery.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(2):343-7.
1999: Shiro Hoshida; Nobushige Yamashita; K Kawahara; Tsunehiko Kuzuya; Masatsugu Hori
Amelioration by quinapril of myocardial infarction induced by coronary occlusion/reperfusion in a rabbit model of atherosclerosis: possible mechanisms.
Circulation 1999;99(3):434-40.
1999: Tetsuo Minamino; Masafumi Kitakaze; Hiroshi Asanuma; Yoko Ueda; Yukihiro Koretsune; Tsunehiko Kuzuya; Masatsugu Hori
Plasma adenosine levels and platelet activation in patients with atrial fibrillation.
The American journal of cardiology 1999;83(2):194-8.
1999: K Inoue; Hiroshi Ito; Masafumi Kitakaze; Tsunehiko Kuzuya; Masatsugu Hori; Katsuomi Iwakura; Nagahiro Nishikawa; Yorihiko Higashino; Kenshi Fujii; Tetsuo Minamino
Antecedent angina pectoris as a predictor of better functional and clinical outcomes in patients with an inferior wall acute myocardial infarction.
The American journal of cardiology 1999;83(2):159-63.
1999: Masafumi Kitakaze; Koichi Node; Tetsuo Minamino; Hiroshi Asanuma; Tsunehiko Kuzuya; Masatsugu Hori
A Ca channel blocker, benidipine, increases coronary blood flow and attenuates the severity of myocardial ischemia via NO-dependent mechanisms in dogs.
Journal of the American College of Cardiology 1999;33(1):242-9.
1998: Masafumi Kitakaze; Hiroharu Funaya; Kazuo Komamura; Koichi Node; Tetsuo Minamino; Hidezo Mori; H Takeda; Tsunehiko Kuzuya; Masatsugu Hori
Nisoldipine selectively induces coronary vasodilation and improves mild myocardial ischemia in dogs: a potential role of cellular acidosis.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1998;12(6):533-41.
1998: Masanori Yabuki; Toshihiko Toyofuku; Kinya Otsu; M Nishida; Tsunehiko Kuzuya; Masatsugu Hori; M Tada
Involvement of NF-Y in transcriptional regulation of the phospholamban gene.
European journal of biochemistry / FEBS 1998;258(2):744-51.
1998: Masafumi Kitakaze; Koichi Node; Tetsuo Minamino; Hiroshi Asanuma; Y Ueda; H Kosaka; Tsunehiko Kuzuya; Masatsugu Hori
Inhibition of angiotensin-converting enzyme increases the nitric oxide levels in canine ischemic myocardium.
Journal of molecular and cellular cardiology 1998;30(11):2461-6.
1998: Tetsuo Minamino; Masafumi Kitakaze; Shoji Sanada; H Asanuama; Toshiya Kurotobi; Yukihiro Koretsune; Masatake Fukunami; Tsunehiko Kuzuya; Noritake Hoki; Masatsugu Hori
Increased expression of P-selectin on platelets is a risk factor for silent cerebral infarction in patients with atrial fibrillation: role of nitric oxide.
Circulation 1998;98(17):1721-7.
1998: Nobushige Yamashita; Shiro Hoshida; Naoyuki Taniguchi; Tsunehiko Kuzuya; Masatsugu Hori
Whole-body hyperthermia provides biphasic cardioprotection against ischemia/reperfusion injury in the rat.
Circulation 1998;98(14):1414-21.
1998: Makoto Nishida; J Igarashi; Tsunehiko Kuzuya
[The role of nitric oxide in ischemia-reperfused heart].
Nihon rinsho. Japanese journal of clinical medicine 1998;56(10):2515-20.
1998: M Morikawa; Hiroshi Sato; H Sato; Yukihiro Koretsune; Yozo Ohnishi; Toshiya Kurotobi; Tsunehiko Kuzuya; Masatsugu Hori
Sustained left ventricular diastolic dysfunction after exercise in patients with dilated cardiomyopathy.
Heart (British Cardiac Society) 1998;80(3):263-9.
1998: Masafumi Kitakaze; Tetsuo Minamino; Koichi Node; Yukihiro Koretsune; Kazuo Komamura; Hiroharu Funaya; Tsunehiko Kuzuya; Masatsugu Hori
Elevation of plasma adenosine levels may attenuate the severity of chronic heart failure.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1998;12(3):307-9.
1998: Nobushige Yamashita; Shiro Hoshida; Naoyuki Taniguchi; Tsunehiko Kuzuya; Masatsugu Hori
A "second window of protection" occurs 24 h after ischemic preconditioning in the rat heart.
Journal of molecular and cellular cardiology 1998;30(6):1181-9.
1998: Toshihiko Toyofuku; Masanori Yabuki; Kinya Otsu; Tsunehiko Kuzuya; Masatsugu Hori; M Tada
Direct association of the gap junction protein connexin-43 with ZO-1 in cardiac myocytes.
The Journal of biological chemistry 1998;273(21):12725-31.
1998: Shiro Hoshida; N Yamashita; Tsunehiko Kuzuya; Masatsugu Hori
Reduction in infarct size by chronic amlodipine treatment in cholesterol-fed rabbits.
Atherosclerosis 1998;138(1):163-70.
1998: Tetsuo Minamino; Masafumi Kitakaze; Yasushi Matsumura; Kazuhiko Nishida; Yoji Kato; Kazuhiko Hashimura; Yasuhiko Matsu-Ura; Hiroharu Funaya; Hiroshi Sato; Tsunehiko Kuzuya; Masatsugu Hori
Impact of coronary risk factors on contribution of nitric oxide and adenosine to metabolic coronary vasodilation in humans.
Journal of the American College of Cardiology 1998;31(6):1274-9.
1998: Tetsuo Minamino; Masafumi Kitakaze; Hiroshi Asanuma; Yoshiaki Tomiyama; Masamichi Shiraga; Hiroshi Sato; Yoko Ueda; Hiroharu Funaya; Tsunehiko Kuzuya; Yuji Matsuzawa; Masatsugu Hori
Endogenous adenosine inhibits P-selectin-dependent formation of coronary thromboemboli during hypoperfusion in dogs.
The Journal of clinical investigation 1998;101(8):1643-53.
1998: Hidehiko Kondo; Tohru Masuyama; Tsunehiko Kuzuya; Masatsugu Hori
[Contrast enhancement using the triggered imaging].
Nihon rinsho. Japanese journal of clinical medicine 1998;56(4):921-5.
1998: Tetsuo Minamino; Masafumi Kitakaze; Hiroshi Sato; Hiroharu Funaya; Yoko Ueda; Hiroshi Asanuma; Tsunehiko Kuzuya; Masatsugu Hori
Effects of ischemic preconditioning on contractile and metabolic function during hypoperfusion in dogs.
The American journal of physiology 1998;274(2 Pt 2):H684-93.
1998: Toshihiko Toyofuku; Masanori Yabuki; Kinya Otsu; Tsunehiko Kuzuya; Masatsugu Hori; M Tada
Intercellular calcium signaling via gap junction in connexin-43-transfected cells.
The Journal of biological chemistry 1998;273(3):1519-28.
1998: J Igarashi; Makoto Nishida; Shiro Hoshida; N Yamashita; H Kosaka; Masatsugu Hori; Tsunehiko Kuzuya; M Tada
Inducible nitric oxide synthase augments injury elicited by oxidative stress in rat cardiac myocytes.
The American journal of physiology 1998;274(1 Pt 1):C245-52.
1997: Shiro Hoshida; Nobushige Yamashita; J Igarashi; K Aoki; Tsunehiko Kuzuya; Masatsugu Hori
Long-term probucol treatment reverses the severity of myocardial injury in watanabe heritable hyperlipidemic rabbits.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(11):2801-7.
1997: Masafumi Kitakaze; Hiroharu Funaya; Tetsuo Minamino; Koichi Node; Hiroshi Sato; Yoko Ueda; Y Okuyama; Tsunehiko Kuzuya; Masatsugu Hori; Kenji Yoshida
Role of protein kinase C-alpha in activation of ecto-5'-nucleotidase in the preconditioned canine myocardium.
Biochemical and biophysical research communications 1997;239(1):171-5.
1997: Toshiya Kurotobi; Hiroshi Sato; Hiroyuki Yokoyama; D Li; Yukihiro Koretsune; Yozo Ohnishi; M Karita; Hiroshi Takeda; Tsunehiko Kuzuya; Masatsugu Hori
Respiratory oxygen cost for dead space challenge is characteristically increased during exercise in patients with chronic heart failure: does it further decrease exercise capacity?
Journal of cardiac failure 1997;3(3):181-8.
1997: Michio Asahi; Junichi Fujii; Toshifumi Takao; Tsunehiko Kuzuya; Masatsugu Hori; Yasutsugu Shimonishi; Naoyuki Taniguchi
The oxidation of selenocysteine is involved in the inactivation of glutathione peroxidase by nitric oxide donor.
The Journal of biological chemistry 1997;272(31):19152-7.
1997: Nobushige Yamashita; Shiro Hoshida; M Nishida; J Igarashi; K Aoki; Masatsugu Hori; Tsunehiko Kuzuya; Michihiko Tada
Time course of tolerance to ischemia-reperfusion injury and induction of heat shock protein 72 by heat stress in the rat heart.
Journal of molecular and cellular cardiology 1997;29(7):1815-21.
1997: Nobushige Yamashita; Shiro Hoshida; M Nishida; J Igarashi; Naoyuki Taniguchi; Michihiko Tada; Tsunehiko Kuzuya; Masatsugu Hori
Heat shock-induced manganese superoxide dismutase enhances the tolerance of cardiac myocytes to hypoxia-reoxygenation injury.
Journal of molecular and cellular cardiology 1997;29(7):1805-13.
1997: Shiro Hoshida; Makoto Nishida; N Yamashita; J Igarashi; K Aoki; Masatsugu Hori; Tsunehiko Kuzuya; M Tada
Vascular angiotensin-converting enzyme activity in cholesterol-fed rabbits: effects of enalapril.
Atherosclerosis 1997;130(1-2):53-9.
1996: N Yamashita; Makoto Nishida; Shiro Hoshida; J Igarashi; Masatsugu Hori; Tsunehiko Kuzuya; M Tada
Alpha 1-adrenergic stimulation induces cardiac tolerance to hypoxia via induction and activation of Mn-SOD.
The American journal of physiology 1996;271(4 Pt 2):H1356-62.
1996: Shiro Hoshida; Makoto Nishida; N Yamashita; J Igarashi; K Aoki; Masatsugu Hori; Tsunehiko Kuzuya; M Tada
Heme oxygenase-1 expression and its relation to oxidative stress during primary culture of cardiomyocytes.
Journal of molecular and cellular cardiology 1996;28(9):1845-55.
1996: K Nishida; Kinya Otsu; Masatsugu Hori; Tsunehiko Kuzuya; M Tada
Cloning and characterization of the 5'-upstream regulatory region of the Ca(2+)-release channel gene of cardiac sarcoplasmic reticulum.
European journal of biochemistry / FEBS 1996;240(2):408-15.
1996: Shiro Hoshida; N Yamashita; J Igarashi; Makoto Nishida; Masatsugu Hori; Tsunehiko Kuzuya; M Tada
A nitric oxide donor reverses myocardial injury in rabbits with acute hypercholesterolemia.
The Journal of pharmacology and experimental therapeutics 1996;278(2):741-6.
1996: Shiro Hoshida; Makoto Nishida; N Yamashita; J Igarashi; Masatsugu Hori; T Kamada; Tsunehiko Kuzuya; M Tada
Amelioration of severity of myocardial injury by a nitric oxide donor in rabbits fed a cholesterol-rich diet.
Journal of the American College of Cardiology 1996;27(4):902-9.
1995: Michio Asahi; Junichi Fujii; Keiichiro Suzuki; H G Seo; Tsunehiko Kuzuya; Masatsugu Hori; M Tada; Shinobu Fujii; Naoyuki Taniguchi
Inactivation of glutathione peroxidase by nitric oxide. Implication for cytotoxicity.
The Journal of biological chemistry 1995;270(36):21035-9.
1995: Shiro Hoshida; N Yamashita; J Igarashi; Makoto Nishida; Masatsugu Hori; T Kamada; Tsunehiko Kuzuya; M Tada
Nitric oxide synthase protects the heart against ischemia-reperfusion injury in rabbits.
The Journal of pharmacology and experimental therapeutics 1995;274(1):413-8.
1995: Y Nakagawa; Hiroshi Ito; Masafumi Kitakaze; Hideo Kusuoka; Masatsugu Hori; Tsunehiko Kuzuya; Yorihiko Higashino; Kenshi Fujii; Tetsuo Minamino
Effect of angina pectoris on myocardial protection in patients with reperfused anterior wall myocardial infarction: retrospective clinical evidence of "preconditioning".
Journal of the American College of Cardiology 1995;25(5):1076-83.
1994: N Yamashita; M Nishida; S Hoshida; Tsunehiko Kuzuya; Masatsugu Hori; N Taniguchi; T Kamada; M Tada
Induction of manganese superoxide dismutase in rat cardiac myocytes increases tolerance to hypoxia 24 hours after preconditioning.
The Journal of clinical investigation 1994;94(6):2193-9.
1994: Tsunehiko Kuzuya; H Fuji; Shiro Hoshida; Makoto Nishida; K Goshima; Masatsugu Hori; T Kamada; M Tada
Polymorphonuclear leukocytes-induced injury in hypoxic cardiac myocytes.
Free radical biology & medicine 1994;17(6):501-10.
1994: Shiro Hoshida; Tsunehiko Kuzuya; Makoto Nishida; N Yamashita; Masatsugu Hori; T Kamada; M Tada
Ebselen protects against ischemia-reperfusion injury in a canine model of myocardial infarction.
The American journal of physiology 1994;267(6 Pt 2):H2342-7.
1994: Shiro Hoshida; Tsunehiko Kuzuya; N Yamashita; Makoto Nishida; S Kitahara; Masatsugu Hori; T Kamada; M Tada
gamma-Glutamylcysteine ethyl ester for myocardial protection in dogs during ischemia and reperfusion.
Journal of the American College of Cardiology 1994;24(5):1391-7.
1994: H Oe; Tsunehiko Kuzuya; Shiro Hoshida; Makoto Nishida; Masatsugu Hori; T Kamada; M Tada
Calcium overload and cardiac myocyte cell damage induced by arachidonate lipoxygenation.
The American journal of physiology 1994;267(4 Pt 2):H1396-402.
1994: Y Kimura; K Otsu; K Nishida; Tsunehiko Kuzuya; M Tada
Thyroid hormone enhances Ca2+ pumping activity of the cardiac sarcoplasmic reticulum by increasing Ca2+ ATPase and decreasing phospholamban expression.
Journal of molecular and cellular cardiology 1994;26(9):1145-54.
1994: Shiro Hoshida; Tsunehiko Kuzuya; Makoto Nishida; N Yamashita; H Oe; Masatsugu Hori; T Kamada; M Tada
Adenosine blockade during reperfusion reverses the infarct limiting effect in preconditioned canine hearts.
Cardiovascular research 1994;28(7):1083-8.
1994: Kinya Otsu; K Nishida; Y Kimura; Tsunehiko Kuzuya; Masatsugu Hori; T Kamada; M Tada
The point mutation Arg615-->Cys in the Ca2+ release channel of skeletal sarcoplasmic reticulum is responsible for hypersensitivity to caffeine and halothane in malignant hyperthermia.
The Journal of biological chemistry 1994;269(13):9413-5.
1993: Tsunehiko Kuzuya; Shiro Hoshida; N Yamashita; H Fuji; H Oe; Masatsugu Hori; T Kamada; M Tada
Delayed effects of sublethal ischemia on the acquisition of tolerance to ischemia.
Circulation research 1993;72(6):1293-9.
1993: Tsunehiko Kuzuya; Shiro Hoshida; Y Kim; H Oe; Masatsugu Hori; T Kamada; M Tada
Free radical generation coupled with arachidonate lipoxygenase reaction relates to reoxygenation induced myocardial cell injury.
Cardiovascular research 1993;27(6):1056-60.
1993: Shiro Hoshida; Tsunehiko Kuzuya; H Fuji; H Oe; Masatsugu Hori; T Kamada; M Tada
Transcardiac alteration of neutrophil function relates to myocardial ischaemia/reperfusion injury.
Cardiovascular research 1993;27(3):377-83.
1993: Shiro Hoshida; Tsunehiko Kuzuya; H Fuji; N Yamashita; H Oe; Masatsugu Hori; Keiichiro Suzuki; Naoyuki Taniguchi; M Tada
Sublethal ischemia alters myocardial antioxidant activity in canine heart.
The American journal of physiology 1993;264(1 Pt 2):H33-9.
1993: Shiro Hoshida; Tsunehiko Kuzuya; N Yamashita; H Oe; H Fuji; Masatsugu Hori; M Tada; T Kamada
Brief myocardial ischemia affects free radical generating and scavenging systems in dogs.
Heart and vessels 1993;8(3):115-20.
1993: M Nishida; Tsunehiko Kuzuya; M Tada
[The regulation of coronary microvascular endothelial cells--the role of myocyte-endothelial cell interaction].
Japanese circulation journal 1993;57 Suppl 4():1211-4.
1992: Takuya Sasaki; M Inui; Y Kimura; Tsunehiko Kuzuya; M Tada
Molecular mechanism of regulation of Ca2+ pump ATPase by phospholamban in cardiac sarcoplasmic reticulum. Effects of synthetic phospholamban peptides on Ca2+ pump ATPase.
The Journal of biological chemistry 1992;267(3):1674-9.
1992: Tsunehiko Kuzuya; Shiro Hoshida; N Yamashita; H Oe; Masatsugu Hori; M Tada; T Kamada; Y Nakagawa; H Fuji; Tetsuo Minamino
[Acquisition of myocardial ischemic tolerance and its clinical significance].
Japanese circulation journal 1992;56 Suppl 5():1442-5.
1991: Tsunehiko Kuzuya; H Fuji; Shiro Hoshida; A Kitabatake; M Tada
Neutrophil-induced myocardial cell damage and active oxygen metabolites.
Japanese circulation journal 1991;55(11):1127-31.
1991: Shiro Hoshida; Tsunehiko Kuzuya; Makoto Nishida; Y Kim; H Fuji; Tetsuo Minamino; A Kitabatake; M Tada; T Kamada
Transcardiac alteration of neutrophil function before and after coronary thrombolysis in human myocardial infarction.
International journal of cardiology 1991;30(1):49-54.
1990: Tsunehiko Kuzuya; H Fuji; M Tada; K Goshima
[Role of oxy-radicals in myocardial oxygen paradox].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1990;35(10):1854-63.
1990: Tsunehiko Kuzuya; Shiro Hoshida; Y Kim; Makoto Nishida; H Fuji; A Kitabatake; M Tada; T Kamada
Detection of oxygen-derived free radical generation in the canine postischemic heart during late phase of reperfusion.
Circulation research 1990;66(4):1160-5.
1990: Makoto Nishida; Tsunehiko Kuzuya; Shiro Hoshida; Y Kim; A Kitabatake; T Kamada; M Tada
Polymorphonuclear leukocytes induced vasoconstriction in isolated canine coronary arteries.
Circulation research 1990;66(1):253-8.
1989: Tsunehiko Kuzuya; Shiro Hoshida; Makoto Nishida; Y Kim; H Fuji; A Kitabatake; T Kamada; M Tada
Role of free radicals and neutrophils in canine myocardial reperfusion injury: myocardial salvage by a novel free radical scavenger, 2-octadecylascorbic acid.
Cardiovascular research 1989;23(4):323-30.
1989: Shiro Hoshida; Tsunehiko Kuzuya; Makoto Nishida; Y Kim; A Kitabatake; T Kamada; M Tada
Attenuation of neutrophil function by inhibitors of arachidonate metabolism reduces the extent of canine myocardial infarction.
The American journal of cardiology 1989;63(10):24E-28E.
1988: Tsunehiko Kuzuya; Y Kimura; Shiro Hoshida; K Kodama; N Nakamura; Y Hamanaka; A Kitabatake; T Kamada; M Tada
The effect of CV-4151, a selective inhibitor of thromboxane synthetase, on prostanoid formation and platelet aggregation in humans.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1988;2(5):693-700.
1988: Tsunehiko Kuzuya; Shiro Hoshida; K Suzuki; T Sasaki; A Kitabatake; T Kamada; Tetsuo Minamino; M Tada
Polymorphonuclear leukocyte activity and ventricular arrhythmia in acute myocardial infarction.
The American journal of cardiology 1988;62(13):868-72.
1988: M Tada; Tsunehiko Kuzuya; Shiro Hoshida; Makoto Nishida
Arachidonate metabolism in myocardial ischemia and reperfusion.
Journal of molecular and cellular cardiology 1988;20 Suppl 2():135-43.
1987: Tsunehiko Kuzuya; Shiro Hoshida; Makoto Nishida; Y Kim; T Kamada; M Tada
Increased production of arachidonate metabolites in an occlusion-reperfusion model of canine myocardial infarction.
Cardiovascular research 1987;21(8):551-8.