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Larry Kwak

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Soung-Chul Cha; Richard E Davis; Shibichakravarthy Kannan; Kunhwa Kim; Sang Kim; Benjamin Kwak; Larry W Kwak; Amber Luong; Juliana Ong; Daniel S Paick; Michael S Popescu; Hong Qin; Seema Rawal; Harry W Schroeder; Leticia S Watkins; Jinsong Wei; Weiguo Wu; Flavio E Baio; Sattva S Neelapu
Nonstereotyped lymphoma B cell receptors recognize vimentin as a shared autoantigen.
Jason R Westin; Vince D Cataldo; Wenli Dong; Michelle A Fanale; Luis E Fayad; Nathan Fowler; Camillo Jimenez; Larry W Kwak; Peter McLaughlin; William A Murphy; Sattva S Neelapu; Barbara Pro; Jorge Romaguera; Felipe Samaniego; Perpetua Sanjorjo; Jatin Shah; Michael A Thompson; Bela Toth; Fredrick B Hagemeister
Zoledronic Acid for Prevention of Bone Loss in Patients Receiving Primary Therapy for Lymphomas: A Prospective, Randomized Controlled Phase III Trial.
Anas Younes; Amanda Copeland; Silvana de Castro Faria; Kantharaj Ethirajulu; Michelle A Fanale; Fredrick Hagemeister; Stefan Hart; Ramesh Jayaraman; Larry W Kwak; Peter McLaughlin; Sattva S Neelapu; Jorge Romaguera; Jatin Shah; Jeanette Wood; Joy Zhu
Phase I study of a novel oral Janus kinase 2 inhibitor, SB1518, in patients with relapsed lymphoma: evidence of clinical and biologic activity in multiple lymphoma subtypes.

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All Publications

2013: Soung-Chul Cha; Richard E Davis; Shibichakravarthy Kannan; Kunhwa Kim; Sang Kim; Benjamin Kwak; Larry W Kwak; Amber Luong; Juliana Ong; Daniel S Paick; Michael S Popescu; Hong Qin; Seema Rawal; Harry W Schroeder; Leticia S Watkins; Jinsong Wei; Weiguo Wu; Flavio E Baio; Sattva S Neelapu
Nonstereotyped lymphoma B cell receptors recognize vimentin as a shared autoantigen.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(9):4887-98.
2013: Jason R Westin; Vince D Cataldo; Wenli Dong; Michelle A Fanale; Luis E Fayad; Nathan Fowler; Camillo Jimenez; Larry W Kwak; Peter McLaughlin; William A Murphy; Sattva S Neelapu; Barbara Pro; Jorge Romaguera; Felipe Samaniego; Perpetua Sanjorjo; Jatin Shah; Michael A Thompson; Bela Toth; Fredrick B Hagemeister
Zoledronic Acid for Prevention of Bone Loss in Patients Receiving Primary Therapy for Lymphomas: A Prospective, Randomized Controlled Phase III Trial.
Clinical lymphoma, myeloma & leukemia 2013;13(2):99-105.
2012: Anas Younes; Amanda Copeland; Silvana de Castro Faria; Kantharaj Ethirajulu; Michelle A Fanale; Fredrick Hagemeister; Stefan Hart; Ramesh Jayaraman; Larry W Kwak; Peter McLaughlin; Sattva S Neelapu; Jorge Romaguera; Jatin Shah; Jeanette Wood; Joy Zhu
Phase I study of a novel oral Janus kinase 2 inhibitor, SB1518, in patients with relapsed lymphoma: evidence of clinical and biologic activity in multiple lymphoma subtypes.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(33):4161-7.
2012: Liang Zhang; Larry W Kwak; Haiyan Li; Jianfei Qian; Jorge Romaguera; Michael Wang; Jing Yang; Qing Yi
Role of the microenvironment in mantle cell lymphoma: IL-6 is an important survival factor for the tumor cells.
Blood 2012;120(18):3783-92.
2012: Jinsheng Weng; Fuliang Chu; David A Delgado; Michelle A Fanale; Luis Fayad; Larry W Kwak; Amber Luong; Hyun Jun Park; Seema Rawal; Jorge Romaguera; Rakesh Sharma; Sattva S Neelapu
TCL1: a shared tumor-associated antigen for immunotherapy against B-cell lymphomas.
Blood 2012;120(8):1613-23.
2012: Anas Younes; Amanda Copeland; Michelle A Fanale; Silvana de Castro Farial; Luis Fayad; Fredrick Hagemeister; Stella Kim; Larry W Kwak; John M Lambert; Rodica Morariu-Zamfir; Sattva S Neelapu; Sandrine Payrard; Jorge Romaguera; Leo I Gordon
Phase I multidose-escalation study of the anti-CD19 maytansinoid immunoconjugate SAR3419 administered by intravenous infusion every 3 weeks to patients with relapsed/refractory B-cell lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(22):2776-82.
2012: Michael Wang; Anas Younes; Ken H Young; Jerome Zeldis; Liang Zhang; Felipe Samaniego; Luhong Sun; Nicolaus Wagner-Bartak; Maria Badillo; Maria Bejarano; Neda Bell; Catriona Byrne; Fernando Cabanillas; Richard Champlin; Wendy Chen; Yiming Chen; Michelle A Fanale; Luis Fayad; Lei Feng; Nathan Fowler; Fredrick Hagemeister; Kimberly Hartig; Larry W Kwak; Peter McLaughlin; Sattva S Neelapu; Kate J Newberry; Jorge Romaguera
Lenalidomide in combination with rituximab for patients with relapsed or refractory mantle-cell lymphoma: a phase 1/2 clinical trial.
The lancet oncology 2012;13(7):716-23.
2012: Sheeba K Thomas; Larry W Kwak
Lymphoma vaccine therapy: next steps after a positive, controlled phase III clinical trial.
Seminars in oncology 2012;39(3):253-62.
2012: Yuhuan Zheng; Liang Zhang; Veera Baladandayuthapani; Jin He; Sungyoul Hong; Larry W Kwak; Yongsheng Lan; Haiyan Li; Heather Lin; Zhiqiang Liu; Yong Lu; Jianfei Qian; Jatin Shah; Sheeba Thomas; Jing Yang; Qing Yi
Novel phosphatidylinositol 3-kinase inhibitor NVP-BKM120 induces apoptosis in myeloma cells and shows synergistic anti-myeloma activity with dexamethasone.
Journal of molecular medicine (Berlin, Germany) 2012;90(6):695-706.
2012: S Vadhan-Raj; M Wang; Anas Younes; X Zhou; Felipe Samaniego; N J Sarlis; J Shah; C E Bueso-Ramos; J E Cortes; Michelle A Fanale; Luis Fayad; N Fowler; Fredrick B Hagemeister; Larry W Kwak; P W McLaughlin; Robert Z Orlowski; Barbara Pro; A Rodriguez; Jorge Romaguera
A randomized trial of a single-dose rasburicase versus five-daily doses in patients at risk for tumor lysis syndrome.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2012;23(6):1640-5.
2011: Ankur Singh; Jinsong Wei; Irina Fernandez; Larry W Kwak; Jian Lin; Hong Qin; Krishnendu Roy
An injectable synthetic immune-priming center mediates efficient T-cell class switching and T-helper 1 response against B cell lymphoma.
Journal of controlled release : official journal of the Controlled Release Society 2011;155(2):184-92.
2011: Jinsheng Weng; Qing Yi; Gheath Alatrash; Soung-Chul Cha; Satoko Matsueda; Jeffrey J Molldrem; Sattva S Neelapu; Michael S Popescu; Michael Wang; Larry W Kwak
Targeting human B-cell malignancies through Ig light chain-specific cytotoxic T lymphocytes.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(18):5945-52.
2011: Stephen J Schuster; Eduardo M Sotomayor; Jane N Winter; Donald A Berry; Elise A Chong; Christopher R Flowers; Barry L Gause; Jon P Gockerman; Elaine S Jaffe; John E Janik; Amy M McCord; Dean S McGaughey; Franco M Muggia; Sattva S Neelapu; Daniel A Nikcevich; Mihaela A Popa; Craig W Reynolds; Carlos F Santos; Larry W Kwak
Vaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(20):2787-94.
2011: Larry W Kwak
Cancer vaccines: moving toward prevention?
Cancer prevention research (Philadelphia, Pa.) 2011;4(7):954-6.
2011: Michelle Fanale; Luis Fayad; Sandra Horowitz; Yuan Ji; Larry W Kwak; Mary Joy Liboon; Cesar Nunez; Uday Popat; Barbara Pro; Felipe Samaniego; Paolo Anderlini; Anas Younes
Phase I study of bortezomib plus ICE (BICE) for the treatment of relapsed/refractory Hodgkin lymphoma.
British journal of haematology 2011;154(2):284-6.
2011: Ippei Sakamaki; Hong Qin; Larry W Kwak
Translational development of vaccination strategies in follicular NHL.
Best practice & research. Clinical haematology 2011;24(2):295-304.
2011: H J Park; Hong Qin; Soung-Chul Cha; R Sharma; Yeonseok Chung; Kimberly Schluns; Sattva S Neelapu; Willem W Overwijk; Patrick Hwu; Larry W Kwak
Induction of TLR4-dependent CD8+ T cell immunity by murine β-defensin2 fusion protein vaccines.
Vaccine 2011;29(18):3476-82.
2011: Jinsheng Weng; Sattva S Neelapu; Alison F Woo; Larry W Kwak
Identification of human idiotype-specific T cells in lymphoma and myeloma.
Current topics in microbiology and immunology 2011;344():193-210.
2010: Hong Qin; Soung-Chul Cha; Sattva S Neelapu; Chengwen Liu; Yi-Hong Wang; Jinsong Wei; Xiao-Feng Qin; Yong-Jun Liu; Larry W Kwak
Generation of an immune microenvironment as a novel mechanism for myotoxins to potentiate genetic vaccines.
Vaccine 2010;28(50):7970-8.
2010: Wencai Ma; Michael Wang; Zhi-Qiang Wang; Luhong Sun; David Graber; Jairo Matthews; Richard Champlin; Qing Yi; Robert Z Orlowski; Larry W Kwak; Donna M Weber; Sheeba K Thomas; Jatin Shah; Steven Kornblau; Richard E Davis
Effect of long-term storage in TRIzol on microarray-based gene expression profiling.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010;19(10):2445-52.
2010: Hong Qin; Pramod N Nehete; Hong He; Bharti Nehete; Stephanie Buchl; Soung-Chul Cha; Jagannadha K Sastry; Larry W Kwak
Prime-boost vaccination using chemokine-fused gp120 DNA and HIV envelope peptides activates both immediate and long-term memory cellular responses in rhesus macaques.
Journal of biomedicine & biotechnology 2010;2010():860160.
2009: Hong Qin; Soung-Chul Cha; Sattva S Neelapu; Yanyan Lou; Jinsong Wei; Yong-Jun Liu; Larry W Kwak
Vaccine site inflammation potentiates idiotype DNA vaccine-induced therapeutic T cell-, and not B cell-, dependent antilymphoma immunity.
Blood 2009;114(19):4142-9.
2009: Jianfei Qian; Sungyoul Hong; Siqing Wang; Liang Zhang; Luhong Sun; Michael Wang; Jing Yang; Larry W Kwak; Jian Hou; Qing Yi
Myeloma cell line-derived, pooled heat shock proteins as a universal vaccine for immunotherapy of multiple myeloma.
Blood 2009;114(18):3880-9.
2009: Ping Shi; Raymond Lai; Quan Lin; Abid S Iqbal; Leah C Young; Larry W Kwak; Richard J Ford; Hesham M Amin
IGF-IR tyrosine kinase interacts with NPM-ALK oncogene to induce survival of T-cell ALK+ anaplastic large-cell lymphoma cells.
Blood 2009;114(2):360-70.
2009: Bita Esmaeli; Peter McLaughlin; Barbara Pro; Felipe Samaniego; Isis Gayed; Fredrick Hagemeister; Jorge Romaguera; Fernando Cabanillas; Sattva S Neelapu; R Banay; Luis Fayad; M Wayne Saville; Larry W Kwak
Prospective trial of targeted radioimmunotherapy with Y-90 ibritumomab tiuxetan (Zevalin) for front-line treatment of early-stage extranodal indolent ocular adnexal lymphoma.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2009;20(4):709-14.
2009: Jing Yang; Yabing Cao; Sungyongl Hong; Haiyan Li; Jianfei Qian; Larry W Kwak; Qing Yi
Human-like mouse models for testing the efficacy and safety of anti-beta2-microglobulin monoclonal antibodies to treat myeloma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(3):951-9.
2008: Ankur Singh; Hui Nie; Bilal Ghosn; Hong Qin; Larry W Kwak; Krishnendu Roy
Efficient modulation of T-cell response by dual-mode, single-carrier delivery of cytokine-targeted siRNA and DNA vaccine to antigen-presenting cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(12):2011-21.
2008: Michael Wang; Luis Fayad; Fernando Cabanillas; Fredrick Hagemeister; Peter McLaughlin; Maria A Rodriguez; Larry W Kwak; Yuhong Zhou; Andrew Lamb; Jorge Romaguera
Phase 2 trial of rituximab plus hyper-CVAD alternating with rituximab plus methotrexate-cytarabine for relapsed or refractory aggressive mantle cell lymphoma.
Cancer 2008;113(10):2734-41.
2008: Sungyoul Hong; Jianfei Qian; Jing Yang; Haiyan Li; Larry W Kwak; Qing Yi
Roles of idiotype-specific t cells in myeloma cell growth and survival: Th1 and CTL cells are tumoricidal while Th2 cells promote tumor growth.
Cancer research 2008;68(20):8456-64.
2008: Yuhong Zhou; Haijun Wang; Wenjing Fang; Jorge E Romaguer; Yanxia Zhang; Kay Delasalle; Larry W Kwak; Qing Yi; Xianglin L Du; Michael Wang
Incidence trends of mantle cell lymphoma in the United States between 1992 and 2004.
Cancer 2008;113(4):791-8.
2008: Issa F Khouri; Peter McLaughlin; Rima M Saliba; Chitra Hosing; Martin Korbling; Ming S Lee; L Jeffrey Medeiros; Luis Fayad; Felipe Samaniego; Amin Alousi; Paolo Anderlini; Daniel Couriel; Marcos De Lima; Sergio Giralt; Sattva S Neelapu; Naoto T Ueno; Barry I Samuels; Fredrick Hagemeister; Larry W Kwak; Richard E Champlin
Eight-year experience with allogeneic stem cell transplantation for relapsed follicular lymphoma after nonmyeloablative conditioning with fludarabine, cyclophosphamide, and rituximab.
Blood 2008;111(12):5530-6.
2008: Michael Wang; Liang Zhang; Xiaohong Han; Jing Yang; Jianfei Qian; Sungyoul Hong; Pei Lin; Yuankai Shi; Jorge Romaguera; Larry W Kwak; Qing Yi
A severe combined immunodeficient-hu in vivo mouse model of human primary mantle cell lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(7):2154-60.
2008: M J Overman; L Feng; Barbara Pro; Peter McLaughlin; Mark Hess; Felipe Samaniego; Anas Younes; Jorge Romaguera; Fredrick B Hagemeister; Larry W Kwak; Fernando Cabanillas; Maria A Rodriguez; Luis Fayad
The addition of rituximab to CHOP chemotherapy improves overall and failure-free survival for follicular grade 3 lymphoma.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19(3):553-9.
2008: Seung-Tae Lee; Shujuan Liu; Laszlo G Radvanyi; Pariya Sukhumalchandra; Jeffrey J Molldrem; Eric Wieder; Patrick Hwu; Yong-Jun Liu; Larry W Kwak; Gregory Lizée; Sattva S Neelapu
A novel strategy for rapid and efficient isolation of human tumor-specific CD4(+) and CD8(+) T-cell clones.
Journal of immunological methods 2008;331(1-2):13-26.
2007: Kuichun Zhu; Hong Qin; Soung-Chul Cha; Sattva S Neelapu; Willem W Overwijk; Gregory A Lizee; James L Abbruzzese; Patrick Hwu; Laszlo G Radvanyi; Larry W Kwak; David Z Chang
Survivin DNA vaccine generated specific antitumor effects in pancreatic carcinoma and lymphoma mouse models.
Vaccine 2007;25(46):7955-61.
2007: Jing Yang; Xiang Zhang; Ji Wang; Jianfei Qian; Liang Zhang; Michael Wang; Larry W Kwak; Qing Yi
Anti beta2-microglobulin monoclonal antibodies induce apoptosis in myeloma cells by recruiting MHC class I to and excluding growth and survival cytokine receptors from lipid rafts.
Blood 2007;110(8):3028-35.
2007: Yeonseok Chung; Hong Qin; Chang-Yuil Kang; Sanghee Kim; Larry W Kwak; Chen Dong
An NKT-mediated autologous vaccine generates CD4 T-cell dependent potent antilymphoma immunity.
Blood 2007;110(6):2013-9.
2007: Jing Yang; Michele Wezeman; Xiang Zhang; Pei Lin; Michael Wang; Jianfei Qian; Bo Wan; Larry W Kwak; Long Yu; Qing Yi
Human C-reactive protein binds activating Fcgamma receptors and protects myeloma tumor cells from apoptosis.
Cancer cell 2007;12(3):252-65.
2007: Jianfei Qian; Jin Xie; Sungyoul Hong; Jing Yang; Liang Zhang; Xiaohong Han; Michael Wang; Fenghuang Zhan; John D Shaughnessy; Joshua Epstein; Larry W Kwak; Qing Yi
Dickkopf-1 (DKK1) is a widely expressed and potent tumor-associated antigen in multiple myeloma.
Blood 2007;110(5):1587-94.
2007: Elias Jabbour; Chitra Hosing; Gregory D Ayers; Rodolfo Nunez; Paolo Anderlini; Barbara Pro; Issa Khouri; Anas Younes; Fredrick Hagemeister; Larry W Kwak; Luis Fayad
Pretransplant positive positron emission tomography/gallium scans predict poor outcome in patients with recurrent/refractory Hodgkin lymphoma.
Cancer 2007;109(12):2481-9.
2007: mircea popescu; Richard J Robb; Michael M Batenjany; Lawrence T Boni; Mary E Neville; Robin Pennington; Sattva S Neelapu; Larry W Kwak
A novel proteoliposomal vaccine elicits potent antitumor immunity in mice.
Blood 2007;109(12):5407-10.
2007: Sattva S Neelapu; Barry L Gause; Linda Harvey; Seung-Tae Lee; Andrea Robin Frye; Jessie Horton; Richard J Robb; mircea popescu; Larry W Kwak
A novel proteoliposomal vaccine induces antitumor immunity against follicular lymphoma.
Blood 2007;109(12):5160-3.
2007: Seung-Tae Lee; Sattva S Neelapu; Larry W Kwak
Therapeutic vaccine for lymphoma.
Yonsei medical journal 2007;48(1):1-10.
2007: Sattva S Neelapu; Larry W Kwak
Vaccine therapy for B-cell lymphomas: next-generation strategies.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2007;():243-9.
2007: Yasuhiro Oki; Peter McLaughlin; Luis Fayad; Barbara Pro; Paul F Mansfield; Gary L Clayman; L Jeffrey Medeiros; Larry W Kwak; Pramod K Srivastava; Anas Younes
Experience with heat shock protein-peptide complex 96 vaccine therapy in patients with indolent non-Hodgkin lymphoma.
Cancer 2007;109(1):77-83.
2006: Siqing Wang; Sungyoul Hong; Jing Yang; Jianfei Qian; Xiang Zhang; Elizabeth J Shpall; Larry W Kwak; Qing Yi
Optimizing immunotherapy in multiple myeloma: Restoring the function of patients' monocyte-derived dendritic cells by inhibiting p38 or activating MEK/ERK MAPK and neutralizing interleukin-6 in progenitor cells.
Blood 2006;108(13):4071-7.
2006: Amar Safdar; Maria A Rodriguez; Luis Fayad; Gilhen H Rodriguez; Barbara Pro; Michael Wang; Jorge Romaguera; Andre Goy; Fredrick B Hagemeister; Peter McLaughlin; Gerald P Bodey; Larry W Kwak; Issam I Raad; Robert B Couch
Dose-related safety and immunogenicity of baculovirus-expressed trivalent influenza vaccine: a double-blind, controlled trial in adult patients with non-Hodgkin B cell lymphoma.
The Journal of infectious diseases 2006;194(10):1394-7.
2006: Jing Yang; Jianfei Qian; Michele Wezeman; Siqing Wang; Pei Lin; Michael Wang; Shmuel Yaccoby; Larry W Kwak; Bart Barlogie; Qing Yi
Targeting beta2-microglobulin for induction of tumor apoptosis in human hematological malignancies.
Cancer cell 2006;10(4):295-307.
2006: Lin Qiu; Raymond Lai; Quan Lin; Esther Lau; David M Thomazy; Daniel Calame; Richard J Ford; Larry W Kwak; Robert A Kirken; Hesham M Amin
Autocrine release of interleukin-9 promotes Jak3-dependent survival of ALK+ anaplastic large-cell lymphoma cells.
Blood 2006;108(7):2407-15.
2006: CAROL KOBRIN; Soung-Chul Cha; Hong Qin; Mark Raffeld; Falko Fend; Leticia Quintanilla-Martinez; Sheldon Grove; Elaine S Jaffe; Larry W Kwak
Molecular analysis of light-chain switch and acute lymphoblastic leukemia transformation in two follicular lymphomas: implications for lymphomagenesis.
Leukemia & lymphoma 2006;47(8):1523-34.
2006: Sudhir Pai Kasturi; Hong Qin; Kassandra S Thomson; Shihab El-Bereir; Soung-Chul Cha; Sattva S Neelapu; Larry W Kwak; Krishnendu Roy
Prophylactic anti-tumor effects in a B cell lymphoma model with DNA vaccines delivered on polyethylenimine (PEI) functionalized PLGA microparticles.
Journal of controlled release : official journal of the Controlled Release Society 2006;113(3):261-70.
2006: Sattva S Neelapu; Seung-Tae Lee; Hong Qin; Soung-Chul Cha; Alison F Woo; Larry W Kwak
Therapeutic lymphoma vaccines: importance of T-cell immunity.
Expert review of vaccines 2006;5(3):381-94.
2006: Soung-Chul Cha; Larry W Kwak; Pier Adelchi Ruffini; Hong Qin; Sattva S Neelapu; Arya Biragyn
Cloning of B cell lymphoma-associated antigens using modified phage-displayed expression cDNA library and immunized patient sera.
Journal of immunological methods 2006;312(1-2):79-93.
2006: Siqing Wang; Jing Yang; Jianfei Qian; Michele Wezeman; Larry W Kwak; Qing Yi
Tumor evasion of the immune system: inhibiting p38 MAPK signaling restores the function of dendritic cells in multiple myeloma.
Blood 2006;107(6):2432-9.
2005: Sattva S Neelapu; Larry W Kwak; CAROL KOBRIN; Craig W Reynolds; John Janik; Kieron Dunleavy; Therese White; Linda Harvey; Robin Pennington; Maryalice Stetler-Stevenson; Elaine S Jaffe; Seth M Steinberg; Ronald E Gress; Frances T Hakim; Wyndham H Wilson
Vaccine-induced tumor-specific immunity despite severe B-cell depletion in mantle cell lymphoma.
Nature medicine 2005;11(9):986-91.
2005: Sattva S Neelapu; Nikhil C Munshi; Sundar Jagannath; Thelma M Watson; Robin Pennington; C Reynolds; Bart Barlogie; Larry W Kwak
Tumor antigen immunization of sibling stem cell transplant donors in multiple myeloma.
Bone marrow transplantation 2005;36(4):315-23.
2005: Kieron Dunleavy; Frances T Hakim; Hyun Kyung Kim; John Janik; Nicole Grant; Takayuki Nakayama; Therese White; George Wright; Larry W Kwak; Ronald E Gress; Giovanna Tosato; Wyndham H Wilson
B-cell recovery following rituximab-based therapy is associated with perturbations in stromal derived factor-1 and granulocyte homeostasis.
Blood 2005;106(3):795-802.
2004: Sattva S Neelapu; Sivasubramanian Baskar; Barry L Gause; CAROL KOBRIN; Thelma M Watson; Andrea Robin Frye; Robin Pennington; Linda Harvey; Elaine S Jaffe; Richard J Robb; mircea popescu; Larry W Kwak
Human autologous tumor-specific T-cell responses induced by liposomal delivery of a lymphoma antigen.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8309-17.
2004: Arya Biragyn; Pier Adelchi Ruffini; Marta Coscia; Linda K Harvey; Sattva S Neelapu; Sivasubramanian Baskar; Ji-Ming Wang; Larry W Kwak
Chemokine receptor-mediated delivery directs self-tumor antigen efficiently into the class II processing pathway in vitro and induces protective immunity in vivo.
Blood 2004;104(7):1961-9.
2004: Pier Adelchi Ruffini; Arya Biragyn; Marta Coscia; Linda K Harvey; Soung-Chul Cha; Bjarne Bogen; Larry W Kwak
Genetic fusions with viral chemokines target delivery of nonimmunogenic antigen to trigger antitumor immunity independent of chemotaxis.
Journal of leukocyte biology 2004;76(1):77-85.
2004: Marta Coscia; Larry W Kwak
Therapeutic idiotype vaccines in B lymphoproliferative diseases.
Expert opinion on biological therapy 2004;4(6):959-63.
2004: Sivasubramanian Baskar; CAROL KOBRIN; Larry W Kwak
Autologous lymphoma vaccines induce human T cell responses against multiple, unique epitopes.
The Journal of clinical investigation 2004;113(10):1498-510.
2004: Oleg Chertov; Arya Biragyn; Larry W Kwak; John T Simpson; Tatiana Boronina; Van M Hoang; DaRue A Prieto; Thomas P Conrads; Timothy D Veenstra; Robert J Fisher
Organic solvent extraction of proteins and peptides from serum as an effective sample preparation for detection and identification of biomarkers by mass spectrometry.
Proteomics 2004;4(4):1195-203.
2004: Larry W Kwak; Sattva S Neelapu; Michael Bishop
Adoptive immunotherapy with antigen-specific T cells in myeloma: a model of tumor-specific donor lymphocyte infusion.
Seminars in oncology 2004;31(1):37-46.
2004: Hongbin Zha; Mark Raffeld; Lu Charboneau; Stefania Pittaluga; Larry W Kwak; Emanuel F Petricoin; Lance A Liotta; Elaine S Jaffe
Similarities of prosurvival signals in Bcl-2-positive and Bcl-2-negative follicular lymphomas identified by reverse phase protein microarray.
Laboratory investigation; a journal of technical methods and pathology 2004;84(2):235-44.
2003: Joost J Oppenheim; Arya Biragyn; Larry W Kwak; De Yang
Roles of antimicrobial peptides such as defensins in innate and adaptive immunity.
Annals of the rheumatic diseases 2003;62 Suppl 2():ii17-21.
2003: Sung-Bae Kim; Sivasubramanian Baskar; Larry W Kwak
In vitro priming of myeloma antigen-specific allogeneic donor T cells with idiotype pulsed dendritic cells.
Leukemia & lymphoma 2003;44(7):1201-8.
2002: Arya Biragyn; Pier Adelchi Ruffini; Cynthia A Leifer; Elena N Klyushnenkova; Alexander N Shakhov; Oleg Chertov; Aiko K Shirakawa; Joshua M Farber; David M Segal; Joost J Oppenheim; Larry W Kwak
Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2.
Science (New York, N.Y.) 2002;298(5595):1025-9.
2002: Pier Adelchi Ruffini; Sattva S Neelapu; Larry W Kwak; Arya Biragyn
Idiotypic vaccination for B-cell malignancies as a model for therapeutic cancer vaccines: from prototype protein to second generation vaccines.
Haematologica 2002;87(9):989-1001.
2002: Arya Biragyn; Igor M Belyakov; Yen-Hung Chow; Dimiter S Dimitrov; Jay A Berzofsky; Larry W Kwak
DNA vaccines encoding human immunodeficiency virus-1 glycoprotein 120 fusions with proinflammatory chemoattractants induce systemic and mucosal immune responses.
Blood 2002;100(4):1153-9.
2002: De Yang; Arya Biragyn; Larry W Kwak; Joost J Oppenheim
Mammalian defensins in immunity: more than just microbicidal.
Trends in immunology 2002;23(6):291-6.
2002: Pier Adelchi Ruffini; Arya Biragyn; Larry W Kwak
Recent advances in multiple myeloma immunotherapy.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2002;56(3):129-32.
2002: Arya Biragyn; Larry W Kwak
Models for lymphoma.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2002;Chapter 20():Unit 20.6.
2002: D Fowler; J Hou; Jason Foley; Frances T Hakim; Jeanne Odom; Kathleen Castro; Charles Carter; Elizabeth J Read; Juan Gea-Banacloche; Claude Kasten-Sportes; Larry W Kwak; W Wilson; B Levine; Carl H June; Ronald E Gress; Michael Bishop
Phase I clinical trial of donor T-helper type-2 cells after immunoablative, reduced intensity allogeneic PBSC transplant.
Cytotherapy 2002;4(5):429-30.
2001: Arya Biragyn; M Surenhu; Dafeng Yang; Pier Adelchi Ruffini; B A Haines; Elena N Klyushnenkova; Joost J Oppenheim; Larry W Kwak
Mediators of innate immunity that target immature, but not mature, dendritic cells induce antitumor immunity when genetically fused with nonimmunogenic tumor antigens.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(11):6644-53.
2001: Sattva S Neelapu; Sivasubramanian Baskar; Larry W Kwak
Detection of keyhole limpet hemocyanin (KLH)-specific immune responses by intracellular cytokine assay in patients vaccinated with idiotype-KLH vaccine.
Journal of cancer research and clinical oncology 2001;127 Suppl 2():R14-9.
2001: Pier Adelchi Ruffini; Larry W Kwak
Immunotherapy of multiple myeloma.
Seminars in hematology 2001;38(3):260-7.
2001: CAROL KOBRIN; M Bendandi; Larry W Kwak
Novel secondary Ig VH gene rearrangement and in-frame Ig heavy chain complementarity-determining region III insertion/deletion variants in de novo follicular lymphoma.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(4):2235-43.
2001: S B Kim; Larry W Kwak
The use of idiotype as a target for clinical immunotherapy of B cell malignancies.
Cancer chemotherapy and biological response modifiers 2001;19():289-95.
2000: Christopher D Gocke; MS Kopreski; Floyd A Benko; LA Sternas; Larry W Kwak
Serum BCL2/IGH DNA in follicular lymphoma patients: a minimal residual disease marker.
Leukemia & lymphoma 2000;39(1-2):165-72.
2000: Arya Biragyn; Larry W Kwak
Designer cancer vaccines are still in fashion.
Nature medicine 2000;6(9):966-8.
2000: Larry W Kwak
Approaches for immunotherapy of lymphomas.
Immunological investigations 2000;29(2):93-5.
2000: K Tani; William Murphy; Oleg Chertov; Rosalba Salcedo; C Y Koh; I Utsunomiya; Satoshi Funakoshi; Osamu Asai; S H Herrmann; Ji Ming Wang; Larry W Kwak; Joost J Oppenheim
Defensins act as potent adjuvants that promote cellular and humoral immune responses in mice to a lymphoma idiotype and carrier antigens.
International immunology 2000;12(5):691-700.
1999: M Bendandi; Christopher D Gocke; CAROL KOBRIN; Floyd A Benko; LA Sternas; Robin Pennington; Thelma M Watson; Craig W Reynolds; Barry L Gause; PL Duffey; Elaine S Jaffe; Stephen Creekmore; Dan Longo; Larry W Kwak
Complete molecular remissions induced by patient-specific vaccination plus granulocyte-monocyte colony-stimulating factor against lymphoma.
Nature medicine 1999;5(10):1171-7.
1999: Arya Biragyn; Larry W Kwak
B-cell malignancies as a model for cancer vaccines: from prototype protein to next generation genetic chemokine fusions.
Immunological reviews 1999;170():115-26.
1999: MS Kopreski; Floyd A Benko; Larry W Kwak; Christopher D Gocke
Detection of tumor messenger RNA in the serum of patients with malignant melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(8):1961-5.
1999: Arya Biragyn; K Tani; M C Grimm; S Weeks; Larry W Kwak
Genetic fusion of chemokines to a self tumor antigen induces protective, T-cell dependent antitumor immunity.
Nature biotechnology 1999;17(3):253-8.
1999: Larry W Kwak; K Thielemans; M Massaia
Idiotypic vaccination as therapy for multiple myeloma.
Seminars in hematology 1999;36(1 Suppl 3):34-7.
1999: LA Sternas; S W Weeks; Larry W Kwak
Mechanisms of resistance against B-cell malignancies induced by vaccination against the immunoglobulin receptor: the case for T-cell immunity.
Cancer treatment and research 1999;99():267-73.
1998: Larry W Kwak; Robin Pennington; L Boni; Augusto C Ochoa; Richard J Robb; mircea popescu
Liposomal formulation of a self lymphoma antigen induces potent protective antitumor immunity.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(8):3637-41.
1997: M L Saxton; Dan Longo; H E Wetzel; H Tribble; W Gregory Alvord; Larry W Kwak; A S Leonard; C D Ullmann; Brendan D Curti; Augusto C Ochoa
Adoptive transfer of anti-CD3-activated CD4+ T cells plus cyclophosphamide and liposome-encapsulated interleukin-2 cure murine MC-38 and 3LL tumors and establish tumor-specific immunity.
Blood 1997;89(7):2529-36.
1997: CAROL KOBRIN; Larry W Kwak
Development of vaccine strategies for the treatment of B-cell malignancies.
Cancer investigation 1997;15(6):577-87.
1996: Larry W Kwak; Robin Pennington; Dan Longo
Active immunization of murine allogeneic bone marrow transplant donors with B-cell tumor-derived idiotype: a strategy for enhancing the specific antitumor effect of marrow grafts.
Blood 1996;87(7):3053-60.
1995: Larry W Kwak; D D Taub; P L Duffey; W I Bensinger; E M Bryant; C W Reynolds; Dan Longo
Transfer of myeloma idiotype-specific immunity from an actively immunised marrow donor.
Lancet 1995;345(8956):1016-20.
1993: Larry W Kwak; V T DeVita; Dan Longo
Lymphomas.
Cancer chemotherapy and biological response modifiers 1993;14():383-426.