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Reijo Laaksonen

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Emma Raitoharju; Ilkka Seppälä; Mari Levula; Leo-Pekka Lyytikäinen; Niku K J Oksala; Thomas Illig; Mika Kähönen; Norman Klopp; Reijo Laaksonen; Terho Lehtimäki
A comparison of the accuracy of Illumina HumanHT-12 v3 Expression BeadChip and TaqMan qRT-PCR gene expression results in patient samples from the Tampere Vascular Study.
Mari Levula; Ari Mennander; Niku Oksala; Jyrki Parkkinen; Teemu Partio; Markku Pelto-Huikko; Jukka Saarinen; Juha-Pekka Salenius; Juhani T Soini; Taija Somppi; Velipekka Suominen; Maarit Venermo; Jyrki Virkkunen; Rainer Zeitlin; Nina Airla; Juha Hautalahti; Otso Järvinen; Mika Kähönen; Leena Kytömäki; Reijo Laaksonen; Terho Lehtimäki
Genes involved in systemic and arterial bed dependent atherosclerosis--Tampere Vascular study.
Jussi A Hernesniemi; Nina Hutri-Kähönen; Antti Jula; Markus Juonala; Mika Kähönen; Johannes Kettunen; Reijo Laaksonen; Tomi Laitinen; Leo-Pekka Lyytikäinen; Nina Mononen; Sarah S Murray; Niku Oksala; Olli T Raitakari; Samuli Ripatti; Nicholas J Schork; Ilkka Seppälä; Erin N Smith; Sathanur R Srinivasan; Leena Taittonen; Jorma Viikari; Gerald S Berenson; Wei Chen; Terho Lehtimäki
Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey--a meta-analysis of three independent studies.

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All Publications

2013: Emma Raitoharju; Ilkka Seppälä; Mari Levula; Leo-Pekka Lyytikäinen; Niku K J Oksala; Thomas Illig; Mika Kähönen; Norman Klopp; Reijo Laaksonen; Terho Lehtimäki
A comparison of the accuracy of Illumina HumanHT-12 v3 Expression BeadChip and TaqMan qRT-PCR gene expression results in patient samples from the Tampere Vascular Study.
Atherosclerosis 2013;226(1):149-52.
2012: Mari Levula; Ari Mennander; Niku Oksala; Jyrki Parkkinen; Teemu Partio; Markku Pelto-Huikko; Jukka Saarinen; Juha-Pekka Salenius; Juhani T Soini; Taija Somppi; Velipekka Suominen; Maarit Venermo; Jyrki Virkkunen; Rainer Zeitlin; Nina Airla; Juha Hautalahti; Otso Järvinen; Mika Kähönen; Leena Kytömäki; Reijo Laaksonen; Terho Lehtimäki
Genes involved in systemic and arterial bed dependent atherosclerosis--Tampere Vascular study.
PloS one 2012;7(4):e33787.
2012: Jussi A Hernesniemi; Nina Hutri-Kähönen; Antti Jula; Markus Juonala; Mika Kähönen; Johannes Kettunen; Reijo Laaksonen; Tomi Laitinen; Leo-Pekka Lyytikäinen; Nina Mononen; Sarah S Murray; Niku Oksala; Olli T Raitakari; Samuli Ripatti; Nicholas J Schork; Ilkka Seppälä; Erin N Smith; Sathanur R Srinivasan; Leena Taittonen; Jorma Viikari; Gerald S Berenson; Wei Chen; Terho Lehtimäki
Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey--a meta-analysis of three independent studies.
PloS one 2012;7(1):e28931.
2011: Hannu Turpeinen; Emma Raitoharju; John W M Creemers; Otso Järvinen; Mika Kähönen; Reijo Laaksonen; Terho Lehtimäki; Mari Levula; Leo-Pekka Lyytikäinen; Niku Oksala; Anna Oksanen; Markku Pelto-Huikko; Marko Pesu
Proprotein convertases in human atherosclerotic plaques: the overexpression of FURIN and its substrate cytokines BAFF and APRIL.
Atherosclerosis 2011;219(2):799-806.
2011: Emma Raitoharju; Matti Tarkka; Thomas Illig; Mika Kähönen; Pekka J Karhunen; Norman Klopp; Reijo Laaksonen; Mari Levula; Leo-Pekka Lyytikäinen; Ari Mennander; Niku Oksala; Terho Lehtimäki
miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study.
Atherosclerosis 2011;219(1):211-7.
2011: Mari Levula; Ari Huovila; Mika Kahonen; Reijo Laaksonen; Terho Lehtimaki; Timo Paavonen; Markku Pelto-Huikko; Matti Tarkka; Timo Valo; Ari Mennander
A disintegrin and metalloprotease -8 and -15 and susceptibility for ascending aortic dissection.
Scandinavian journal of clinical and laboratory investigation 2011;71(6):515-22.
2011: Emma Raitoharju; Ilkka Seppälä; Matti Tarkka; Jari Viik; Rami Lehtinen; Mari Levula; Kjell Nikus; Niku Oksala; Markku Pelto-Huikko; Ari-Pekka J Huovila; Thomas Illig; Mika Kähönen; Pekka J Karhunen; Norman Klopp; Pekka Kuukasjärvi; Reijo Laaksonen; Jari Laurikka; Terho Lehtimäki
Common variation in the ADAM8 gene affects serum sADAM8 concentrations and the risk of myocardial infarction in two independent cohorts.
Atherosclerosis 2011;218(1):127-33.
2011: Evrim Komurcu-Bayrak; Altan Onat; Berna Yuzbasiogullari; Nina Mononen; Reijo Laaksonen; Mika Kähönen; Gulay Hergenc; Terho Lehtimäki; Nihan Erginel-Unaltuna
The APOE -219G/T and +113G/C polymorphisms affect insulin resistance among Turks.
Metabolism: clinical and experimental 2011;60(5):655-63.
2010: Bilge Ozsait; Evrim Komurcu-Bayrak; Mari Levula; Nihan Erginel-Unaltuna; Mika Kähönen; Myriam Rai; Terho Lehtimäki; Reijo Laaksonen
Niemann-Pick type C fibroblasts have a distinct microRNA profile related to lipid metabolism and certain cellular components.
Biochemical and biophysical research communications 2010;403(3-4):316-21.
2010: Hannu Päivä; Mika Kähönen; Terho Lehtimäki; Georg Alfthan; Jorma Viikari; Reijo Laaksonen; Nina Hutri-Kähönen; Tomi Laitinen; Leena Taittonen; Olli T Raitakari; Markus Juonala
Levels of asymmetrical dimethylarginine are predictive of brachial artery flow-mediated dilation 6 years later. The Cardiovascular Risk in Young Finns Study.
Atherosclerosis 2010;212(2):512-5.
2010: Niku Oksala; Mari Levula; Markku Pelto-Huikko; Leena Kytömäki; Juhani T Soini; Juha Salenius; Mika Kähönen; Pekka J Karhunen; Reijo Laaksonen; Seppo Parkkila; Terho Lehtimäki
Carbonic anhydrases II and XII are up-regulated in osteoclast-like cells in advanced human atherosclerotic plaques-Tampere Vascular Study.
Annals of medicine 2010;42(5):360-70.
2010: Pirjo Valtonen; Kari Punnonen; Heli Saarelainen; Nonna Heiskanen; Olli T Raitakari; Markus Juonala; Jorma S A Viikari; Georg Alfthan; Mika Kähönen; Reijo Laaksonen; Tiina Lyyra-Laitinen; Tomi Laitinen; Seppo Heinonen
ADMA concentration changes across the menstrual cycle and during oral contraceptive use: the Cardiovascular Risk in Young Finns Study.
European journal of endocrinology / European Federation of Endocrine Societies 2010;162(2):259-65.
2010: Petri Niinisalo; Niku Oksala; Mari Levula; Markku Pelto-Huikko; Otso Järvinen; Juha-Pekka Salenius; Leena Kytömäki; Juhani T Soini; Mika Kähönen; Reijo Laaksonen; Mikko Hurme; Terho Lehtimäki
Activation of indoleamine 2,3-dioxygenase-induced tryptophan degradation in advanced atherosclerotic plaques: Tampere vascular study.
Annals of medicine 2010;42(1):55-63.
2010: Auli Sirén; Anne Polvi; Lyne Chahine; Malgorzata Labuda; Sarah Bourgoin; Anna-Kaisa Anttonen; Maria Kousi; Kari Hirvonen; Kalle O J Simola; Eva Andermann; Asta Laiho; Juhani Soini; Matti Koivikko; Reijo Laaksonen; Massimo Pandolfo; Anna-Elina Lehesjoki
Suggestive evidence for a new locus for epilepsy with heterogeneous phenotypes on chromosome 17q.
Epilepsy research 2010;88(1):65-75.
2009: E Komurcu-Bayrak; Nihan Erginel-Unaltuna; Altan Onat; B Ozsait; C Eklund; M Hurme; N Mononen; Reijo Laaksonen; G Hergenc; T Lehtimäki
Association of C-reactive protein (CRP) gene allelic variants with serum CRP levels and hypertension in Turkish adults.
Atherosclerosis 2009;206(2):474-9.
2009: Mari Levula; Nina Airla; Niku Oksala; Jussi A Hernesniemi; Markku Pelto-Huikko; Juha-Pekka Salenius; Rainer Zeitlin; Otso Järvinen; Ari-Pekka J Huovila; Seppo T Nikkari; Olli Jaakkola; Erkki Ilveskoski; Jussi Mikkelsson; Markus Perola; Reijo Laaksonen; Leena Kytömäki; Juhani T Soini; Mika Kähönen; Jyrki Parkkinen; Pekka J Karhunen; Terho Lehtimäki
ADAM8 and its single nucleotide polymorphism 2662 T/G are associated with advanced atherosclerosis and fatal myocardial infarction: Tampere vascular study.
Annals of medicine 2009;41(7):497-507.
2009: Niku Oksala; Mari Levula; Nina Airla; Markku Pelto-Huikko; Rebekka M Ortiz; Otso Järvinen; Juha-Pekka Salenius; Bilge Ozsait; Evrim Komurcu-Bayrak; Nihan Erginel-Unaltuna; Ari-Pekka J Huovila; Leena Kytömäki; Juhani T Soini; Mika Kähönen; Pekka J Karhunen; Reijo Laaksonen; Terho Lehtimäki
ADAM-9, ADAM-15, and ADAM-17 are upregulated in macrophages in advanced human atherosclerotic plaques in aorta and carotid and femoral arteries--Tampere vascular study.
Annals of medicine 2009;41(4):279-90.
2008: Hannu Päivä; Mika Kähönen; Terho Lehtimäki; Olli T Raitakari; Antti Jula; Jorma Viikari; Georg Alfthan; Markus Juonala; Reijo Laaksonen; Nina Hutri-Kähönen
Asymmetric dimethylarginine (ADMA) has a role in regulating systemic vascular tone in young healthy subjects: the cardiovascular risk in young Finns study.
American journal of hypertension 2008;21(8):873-8.
2008: Heiner K. Berthold; Reijo Laaksonen; Terho Lehtimäki; H Gylling; W Krone; Ioanna Gouni-Berthold
SREBP-1c gene polymorphism is associated with increased inhibition of cholesterol-absorption in response to ezetimibe treatment.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2008;116(5):262-7.
2008: Laura Riihimäki; Anna Galkin; Moshe Finel; Jonna Heikura; Kaija H Valkonen; Vesa Virtanen; Reijo Laaksonen; J Peter Slotte; Pia Vuorela
Transport properties of bovine and reindeer beta-lactoglobulin in the Caco-2 cell model.
International journal of pharmaceutics 2008;347(1-2):1-8.
2007: Aloys De Windt; MYRIAM RAI; Lise Bernier; Karin M Thelen; Juhani T Soini; Chantal Lefebvre; Satyan Chintawar; Jacques Lavigne; Lilli Saarinen; Leena Kytömäki; Jon Scott Munzer; Dieter Lütjohann; Massimo Pandolfo; Jean Davignon; Nabil G Seidah; Reijo Laaksonen
Gene set enrichment analysis reveals several globally affected pathways due to SKI-1/S1P inhibition in HepG2 cells.
DNA and cell biology 2007;26(11):765-72.
2007: Virpi Hemminki; Juha Laakso; Mika Kähönen; Väinö Turjanmaa; Hannu Uusitalo; Terho Lehtimäki; Inkeri Ruokonen; Reijo Laaksonen; Heini Huhtala; Hannu Päivä
Plasma asymmetric dimethylarginine and retinal vessel diameters in middle-aged men.
Metabolism: clinical and experimental 2007;56(10):1305-10.
2007: Aloys De Windt; MYRIAM RAI; Leena Kytömäki; Karin M Thelen; Dieter Lütjohann; Lise Bernier; Jean Davignon; Juhani T Soini; Massimo Pandolfo; Reijo Laaksonen
Gene set enrichment analyses revealed several affected pathways in Niemann-pick disease type C fibroblasts.
DNA and cell biology 2007;26(9):665-71.
2007: Tuomo Nieminen; Juhani Knuuti; Päivi Hämelahti; Mika Kähönen; Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Hannu Jokela; Terho Lehtimäki
Coronary reactivity, homocysteine and methylenetetrahydrofolate reductase gene variation in young men during pravastatin therapy.
Vascular pharmacology 2007;47(2-3):113-7.
2007: Tuomo Nieminen; Jussi Matinheikki; Arja Nenonen; Katriina Kukkonen-Harjula; Virpi Lindi; Päivi Hämelahti; Reijo Laaksonen; Yue-Mei Fan; Mika Kähönen; Mikael Fogelholm; Terho Lehtimäki
The relationship of sterol regulatory element-binding protein cleavage-activation protein and apolipoprotein E gene polymorphisms with metabolic changes during weight reduction.
Metabolism: clinical and experimental 2007;56(7):876-80.
2007: B A Schick; Reijo Laaksonen; Jiri J Frohlich; Hannu Päivä; Terho Lehtimäki; K H Humphries; H C F Côté
Decreased skeletal muscle mitochondrial DNA in patients treated with high-dose simvastatin.
Clinical pharmacology and therapeutics 2007;81(5):650-3.
2007: Mari Luomala; Hannu Päivä; Karin M Thelen; Reijo Laaksonen; Marika Saarela; Kari Mattila; Dieter Lütjohann; Terho Lehtimaki
Osteopontin levels are associated with cholesterol synthesis markers in mildly hypercholesterolaemic patients.
Acta cardiologica 2007;62(2):177-81.
2007: Shérine Abboud; Pekka J Karhunen; Dieter Lütjohann; Sirkka Goebeler; Teemu M. Luoto; Silvia Friedrichs; Terho Lehtimaki; Massimo Pandolfo; Reijo Laaksonen
Proprotein convertase subtilisin/kexin type 9 (PCSK9) gene is a risk factor of large-vessel atherosclerosis stroke.
PloS one 2007;2(10):e1043.
2007: E Ilveskoski; Terho Lehtimäki; Reijo Laaksonen; Tuula Janatuinen; R Vesalainen; Pirjo Nuutila; Pekka Laippala; Pekka J Karhunen; Juhani Knuuti
Improvement of myocardial blood flow by lipid-lowering therapy with pravastatin is modulated by apolipoprotein E genotype.
Scandinavian journal of clinical and laboratory investigation 2007;67(7):723-34.
2007: Mika Kähönen; T Lehtimäki; Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; H Laine; Olli T Raitakari; Pirjo Nuutila; Juhani Knuuti; Tuomo Nieminen
Angiotensin-converting enzyme gene polymorphism and coronary reactivity in young men.
Scandinavian journal of clinical and laboratory investigation 2007;67(6):596-603.
2007: Mari Luomala; Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Marika Saarela; Kari Mattila; M Kalijärvi; Tiina Solakivi; Juhani Knuuti; Mikko Hurme; Terho Lehtimäki
High plasma levels of CD40 are associated with low coenzyme Q and vitamin E content of low-density lipoprotein in healthy men.
Scandinavian journal of clinical and laboratory investigation 2007;67(2):115-22.
2006: Mari Luomala; Hannu Päivä; Reijo Laaksonen; Karin M Thelen; Dieter Lütjohann; Nina Peltonen; Terho Lehtimäki
Plasma-soluble CD40 is related to cholesterol metabolism in patients with moderate hypercholesterolemia.
Scandinavian cardiovascular journal : SCJ 2006;40(5):280-4.
2006: Yue-Mei Fan; Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; Hanna Laine; Olli T Raitakari; Pirjo Nuutila; Juhani Knuuti; Riikka Rontu; Terho Lehtimäki
The influence of hepatic lipase C-480T polymorphism on coronary flow reserve in young men is independent of the plasma cholesterol level.
Atherosclerosis 2006;188(2):391-7.
2006: Hannu Päivä; Juha Laakso; Inkeri Ruokonen; Mari Luomala; Marika Saarela; Tiina Solakivi; Saara Metso; Matti Nikkilä; Erkki Wuolijoki; Reijo Laaksonen; Terho Lehtimäki
Plasma asymmetric dimethylarginine (ADMA), nitrate and the indices of low-density lipoprotein oxidation.
Clinica chimica acta; international journal of clinical chemistry 2006;371(1-2):97-101.
2006: Karin M Thelen; Reijo Laaksonen; Hannu Päivä; Terho Lehtimäki; Dieter Lütjohann
High-dose statin treatment does not alter plasma marker for brain cholesterol metabolism in patients with moderately elevated plasma cholesterol levels.
Journal of clinical pharmacology 2006;46(7):812-6.
2006: Reijo Laaksonen
On the mechanisms of statin-induced myopathy.
Clinical pharmacology and therapeutics 2006;79(6):529-31.
2006: Hannu Päivä; Juha Laakso; Mika Kähönen; Väinö Turjanmaa; Tiit Kööbi; Silja Majahalme; Terho Lehtimäki; Inkeri Ruokonen; Reijo Laaksonen
Asymmetric dimethylarginine and hemodynamic regulation in middle-aged men.
Metabolism: clinical and experimental 2006;55(6):771-7.
2006: Reijo Laaksonen; Karin M Thelen; Hannu Päivä; Jussi Matinheikki; Risto Vesalainen; Tuula Janatuinen; Juhani Knuuti; Riikka Rontu; Klaus Von Bergmann; Dieter Lütjohann; Terho Lehtimäki
Genetic variant of the SREBF-1 gene is significantly related to cholesterol synthesis in man.
Atherosclerosis 2006;185(1):206-9.
2006: Reijo Laaksonen; Mikko Katajamaa; Hannu Päivä; Marko Sysi-Aho; Lilli Saarinen; Päivi Junni; Dieter Lütjohann; Joél Smet; Rudy Van Coster; Tuulikki Seppänen-Laakso; Terho Lehtimäki; Juhani T Soini; Matej Oresic
A systems biology strategy reveals biological pathways and plasma biomarker candidates for potentially toxic statin-induced changes in muscle.
PloS one 2006;1():e97.
2006: Karin M Thelen; Dieter Lütjohann; Risto Vesalainen; Tuula Janatuinen; Juhani Knuuti; Klaus Von Bergmann; Terho Lehtimäki; Reijo Laaksonen
Effect of pravastatin on plasma sterols and oxysterols in men.
European journal of clinical pharmacology 2006;62(1):9-14.
2005: Veli-Pekka Valkonen; Tomi-Pekka Tuomainen; Reijo Laaksonen
DDAH gene and cardiovascular risk.
Vascular medicine (London, England) 2005;10 Suppl 1():S45-8.
2005: Hannu Päivä; Karin M Thelen; Rudy Van Coster; Joél Smet; Boel De Paepe; Kari M Mattila; Juha Laakso; Terho Lehtimäki; Klaus Von Bergmann; Dieter Lütjohann; Reijo Laaksonen
High-dose statins and skeletal muscle metabolism in humans: a randomized, controlled trial.
Clinical pharmacology and therapeutics 2005;78(1):60-8.
2004: Tarja A Kunnas; Terho Lehtimäki; Pekka J Karhunen; Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Juhani Knuuti; Seppo T Nikkari
Estrogen receptor genotype modulates myocardial perfusion in young men.
Journal of molecular medicine (Berlin, Germany) 2004;82(12):821-5.
2004: Janne Aittoniemi; Yue-Mei Fan; Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Juhani Knuuti; Janne Hulkkonen; Mikko Hurme; Terho Lehtimäki
The effect of mannan-binding lectin variant alleles on coronary artery reactivity in healthy young men.
International journal of cardiology 2004;97(2):317-8.
2004: Veli-Pekka Valkonen; Reijo Laaksonen
Asymmetric dimethylarginine (ADMA) and acute vascular events.
Clinica chimica acta; international journal of clinical chemistry 2004;348(1-2):9-17.
2004: Hannu Päivä; Terho Lehtimäki; Juha Laakso; Inkeri Ruokonen; Riitta Tervonen; Saara Metso; Matti Nikkilä; Erkki Wuolijoki; Reijo Laaksonen
Dietary composition as a determinant of plasma asymmetric dimethylarginine in subjects with mild hypercholesterolemia.
Metabolism: clinical and experimental 2004;53(8):1072-5.
2004: Riikka Mäkelä; Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Olli Jaakkola; Juhani Knuuti; Terho Lehtimäki
Myeloperoxidase gene variation and coronary flow reserve in young healthy men.
Journal of biomedical science 2004;11(1):59-64.
2003: Veli-Pekka Valkonen; Juha Laakso; Hannu Päivä; Terho Lehtimäki; Timo A Lakka; Marja Isomustajärvi; Inkeri Ruokonen; Jukka T Salonen; Reijo Laaksonen
Asymmetrical dimethylarginine (ADMA) and risk of acute coronary events. Does statin treatment influence plasma ADMA levels?
Atherosclerosis. Supplements 2003;4(4):19-22.
2003: Terho Lehtimäki; Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Kari Mattila; Erkki Ilveskoski; Mari Luomala; Pekka Saikku; Juhani Knuuti; Mikko Hurme
Interleukin-1B genotype modulates the improvement of coronary artery reactivity by lipid-lowering therapy with pravastatin: a placebo-controlled positron emission tomography study in young healthy men.
Pharmacogenetics 2003;13(10):633-9.
2003: Hannu Päivä; Terho Lehtimäki; Juha Laakso; Inkeri Ruokonen; Vappu Rantalaiho; Ole Wirta; Amos Pasternack; Reijo Laaksonen
Plasma concentrations of asymmetric-dimethyl-arginine in type 2 diabetes associate with glycemic control and glomerular filtration rate but not with risk factors of vasculopathy.
Metabolism: clinical and experimental 2003;52(3):303-7.
2003: Hannu Päivä; Juha Laakso; Terho Lehtimäki; Marja Isomustajärvi; Inkeri Ruokonen; Reijo Laaksonen
Effect of high-dose statin treatment on plasma concentrations of endogenous nitric oxide synthase inhibitors.
Journal of cardiovascular pharmacology 2003;41(2):219-22.
2003: Tuula Janatuinen; Juha Laakso; Reijo Laaksonen; Risto Vesalainen; Pirjo Nuutila; Terho Lehtimäki; Olli T Raitakari; Juhani Knuuti
Plasma asymmetric dimethylarginine modifies the effect of pravastatin on myocardial blood flow in young adults.
Vascular medicine (London, England) 2003;8(3):185-9.
2002: Tarja A Kunnas; Terho Lehtimäki; Reijo Laaksonen; Erkki Ilveskoski; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Pekka J Karhunen; Juhani Knuuti; Seppo T Nikkari
Endothelial nitric oxide synthase genotype modulates the improvement of coronary blood flow by pravastatin: a placebo-controlled PET study.
Journal of molecular medicine (Berlin, Germany) 2002;80(12):802-7.
2002: Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; Terho Lehtimäki; Irina Elovaara; Olli Jaakkola; Hannu Jokela; Juha Laakso; Pirjo Nuutila; K Punnonen; Olli T Raitakari; P Saikku; Kimmo Salminen; Juhani Knuuti
High oxidized LDL and elevated plasma homocysteine contribute to the early reduction of myocardial flow reserve in healthy adults.
European journal of clinical investigation 2002;32(11):795-802.
2002: Hannu Päivä; Juha Laakso; Hanna Laine; Reijo Laaksonen; Juhani Knuuti; Olli T Raitakari
Plasma asymmetric dimethylarginine and hyperemic myocardial blood flow in young subjects with borderline hypertension or familial hypercholesterolemia.
Journal of the American College of Cardiology 2002;40(7):1241-7.
2002: Terho Lehtimäki; Reijo Laaksonen; Kari M Mattila; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Juha Laakso; Olli Jaakkola; Timo Koivula; Juhani Knuuti
Oestrogen receptor gene variation is a determinant of coronary reactivity in healthy young men.
European journal of clinical investigation 2002;32(6):400-4.
2001: Veli-Pekka Valkonen; Hannu Päivä; Jukka T Salonen; Timo A Lakka; Terho Lehtimäki; Juha Laakso; Reijo Laaksonen
Risk of acute coronary events and serum concentration of asymmetrical dimethylarginine.
Lancet 2001;358(9299):2127-8.
2001: Yue-Mei Fan; Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Juhani Knuuti; Terho Lehtimäki
Effects of pravastatin therapy on serum lipids and coronary reactivity are not associated with SREBP cleavage-activating protein polymorphism in healthy young men.
Clinical genetics 2001;60(4):319-21.
2001: R Malin; Reijo Laaksonen; Juhani Knuuti; Tuula Janatuinen; Risto Vesalainen; Pirjo Nuutila; Terho Lehtimäki
Paraoxonase genotype modifies the effect of pravastatin on high-density lipoprotein cholesterol.
Pharmacogenetics 2001;11(7):625-33.
2001: Tuula Janatuinen; Reijo Laaksonen; Risto Vesalainen; Olli T Raitakari; Terho Lehtimäki; Pirjo Nuutila; Juhani Knuuti
Effect of lipid-lowering therapy with pravastatin on myocardial blood flow in young mildly hypercholesterolemic adults.
Journal of cardiovascular pharmacology 2001;38(4):561-8.
2001: R Malin; Juhani Knuuti; Tuula Janatuinen; Reijo Laaksonen; Risto Vesalainen; Pirjo Nuutila; Hannu Jokela; J Laakso; Olli Jaakkola; Tiina Solakivi; Terho Lehtimäki
Paraoxonase gene polymorphisms and coronary reactivity in young healthy men.
Journal of molecular medicine (Berlin, Germany) 2001;79(8):449-58.
2001: Anne Kalela; Reijo Laaksonen; Terho Lehtimäki; Tommi A Koivu; Matti Höyhtyä; Tuula Janatuinen; Perttu J Pöllänen; Risto Vesalainen; P Saikku; Juhani Knuuti; Seppo T Nikkari
Effect of pravastatin in mildly hypercholesterolemic young men on serum matrix metalloproteinases.
The American journal of cardiology 2001;88(2):173-5, A6.
2001: Y Fan; Reijo Laaksonen; Tuula Janatuinen; Risto Vesalainen; P Nuutila; Timo Koivula; J Knuuti; T Lehtimäki
Hepatic lipase gene variation is related to coronary reactivity in healthy young men.
European journal of clinical investigation 2001;31(7):574-80.
2001: Olli Laakso; Matti Haapala; Pekka A Jaakkola; Reijo Laaksonen; K Luomanmäki; Jenni M Nieminen; Mika Pettersson; Hannu Päivä; Markku Räsänen; Jaakko-Juhani Himberg
FT-IR breath test in the diagnosis and control of treatment of methanol intoxications.
Journal of analytical toxicology 2001;25(1):26-30.
2000: Olli Laakso; Matti Haapala; Pekka A Jaakkola; Reijo Laaksonen; Jenni M Nieminen; Mika Pettersson; Markku Räsänen; Jaakko-Juhani Himberg
The use of low-resolution FT-IR spectrometry for the analysis of alcohols in breath.
Journal of analytical toxicology 2000;24(4):250-6.