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Bernard Labedan

Research Profile

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Publications

TOP 3
Sandrine Grossetête; Bernard Labedan; Olivier Lespinet
FUNGIpath: a tool to assess fungal metabolic pathways predicted by orthology.
Nicolas Glansdorff; Ying Xu; Bernard Labedan
The conflict between horizontal gene transfer and the safeguard of identity: origin of meiotic sexuality.
Nicolas Glansdorff; Ying Xu; Bernard Labedan
The origin of life and the last universal common ancestor: do we need a change of perspective?

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All Publications

2010: Sandrine Grossetête; Bernard Labedan; Olivier Lespinet
FUNGIpath: a tool to assess fungal metabolic pathways predicted by orthology.
BMC genomics 2010;11():81.
2009: Nicolas Glansdorff; Ying Xu; Bernard Labedan
The conflict between horizontal gene transfer and the safeguard of identity: origin of meiotic sexuality.
Journal of molecular evolution 2009;69(5):470-80.
2009: Nicolas Glansdorff; Ying Xu; Bernard Labedan
The origin of life and the last universal common ancestor: do we need a change of perspective?
Research in microbiology 2009;160(7):522-8.
2008: Frédéric Lemoine; Bernard Labedan; Christine Froidevaux
GenoQuery: a new querying module for functional annotation in a genomic warehouse.
Bioinformatics (Oxford, England) 2008;24(13):i322-9.
2008: Stéphane Descorps-Declère; Frédéric Lemoine; Quentin Sculo; Olivier Lespinet; Bernard Labedan
The multiple facets of homology and their use in comparative genomics to study the evolution of genes, genomes, and species.
Biochimie 2008;90(4):595-608.
2008: Frédéric Lemoine; Bernard Labedan; Olivier Lespinet
SynteBase/SynteView: a tool to visualize gene order conservation in prokaryotic genomes.
BMC bioinformatics 2008;9():536.
2008: Stéphane Descorps-Declère; Matthieu Barba; Bernard Labedan
Matching curated genome databases: a non trivial task.
BMC genomics 2008;9():501.
2008: Nicolas Glansdorff; Ying Xu; Bernard Labedan
The last universal common ancestor: emergence, constitution and genetic legacy of an elusive forerunner.
Biology direct 2008;3():29.
2007: Ying Xu; Bernard Labedan; Nicolas Glansdorff
Surprising arginine biosynthesis: a reappraisal of the enzymology and evolution of the pathway in microorganisms.
Microbiology and molecular biology reviews : MMBR 2007;71(1):36-47.
2007: Frédéric Lemoine; Olivier Lespinet; Bernard Labedan
Assessing the evolutionary rate of positional orthologous genes in prokaryotes using synteny data.
BMC evolutionary biology 2007;7():237.
2006: Olivier Lespinet; Bernard Labedan
Orphan enzymes could be an unexplored reservoir of new drug targets.
Drug discovery today 2006;11(7-8):300-5.
2006: Olivier Lespinet; Bernard Labedan
Puzzling over orphan enzymes.
Cellular and molecular life sciences : CMLS 2006;63(5):517-23.
2006: Olivier Lespinet; Bernard Labedan
ORENZA: a web resource for studying ORphan ENZyme activities.
BMC bioinformatics 2006;7():436.
2006: Bernard Labedan; Olivier Lespinet
Interspecies and intraspecies comparison of microbial proteins: learning about gene ancestry, protein function, and species life style.
Methods of biochemical analysis 2006;49():415-36.
2006: Ying Xu; Nicolas Glansdorff; Bernard Labedan
Bioinformatic analysis of an unusual gene-enzyme relationship in the arginine biosynthetic pathway among marine gamma proteobacteria: implications concerning the formation of N-acetylated intermediates in prokaryotes.
BMC genomics 2006;7():4.
2005: Olivier Lespinet; Bernard Labedan
Orphan enzymes?
Science (New York, N.Y.) 2005;307(5706):42.
2004: Daniil G Naumoff; Ying Xu; Victor Stalon; Nicolas Glansdorff; Bernard Labedan
The difficulty of annotating genes: the case of putrescine carbamoyltransferase.
Microbiology (Reading, England) 2004;150(Pt 12):3908-11.
2004: Daniil G Naumoff; Ying Xu; Nicolas Glansdorff; Bernard Labedan
Retrieving sequences of enzymes experimentally characterized but erroneously annotated : the case of the putrescine carbamoyltransferase.
BMC genomics 2004;5(1):52.
2004: Bernard Labedan; Ying Xu; Daniil G Naumoff; Nicolas Glansdorff
Using quaternary structures to assess the evolutionary history of proteins: the case of the aspartate carbamoyltransferase.
Molecular biology and evolution 2004;21(2):364-73.
2003: Carin Ribard; Michel Rochet; Bernard Labedan; Bertrand Daignan-Fornier; Pedro Alzari; Claudio Scazzocchio; Nathalie Oestreicher
Sub-families of alpha/beta barrel enzymes: a new adenine deaminase family.
Journal of molecular biology 2003;334(5):1117-31.
2002: Stéphanie Le Bouder-Langevin; Isabelle Capron-Montaland; Renaud de Rosa; Bernard Labedan
A strategy to retrieve the whole set of protein modules in microbial proteomes.
Genome research 2002;12(12):1961-73.
2002: Mohamed Zouine; Quentin Sculo; Bernard Labedan
Correct assignment of homology is crucial when genomics meets molecular evolution.
Comparative and functional genomics 2002;3(6):488-93.
2002: Ping Liang; Bernard Labedan; Monica Riley
Physiological genomics of Escherichia coli protein families.
Physiological genomics 2002;9(1):15-26.
1999: Bernard Labedan; A Boyen; M Baetens; Daniel Charlier; P Chen; Raymond Cunin; V Durbeco; Nicolas Glansdorff; G Herve; Christianne Legrain; Z Liang; Cristina Purcarea; Martine Roovers; R Sanchez; T L Toong; Mark Van de Casteele; F Van Vliet; Y Xu; Y F Zhang
The evolutionary history of carbamoyltransferases: A complex set of paralogous genes was already present in the last universal common ancestor.
Journal of molecular evolution 1999;49(4):461-73.
1998: Emmanuelle Gérard; Bernard Labedan; Patrick Forterre
Isolation of a minD-like gene in the hyperthermophilic archaeon Pyrococcus AL585, and phylogenetic characterization of related proteins in the three domains of life.
Gene 1998;222(1):99-106.
1998: Renaud de Rosa; Bernard Labedan
The evolutionary relationships between the two bacteria Escherichia coli and Haemophilus influenzae and their putative last common ancestor.
Molecular biology and evolution 1998;15(1):17-27.
1997: Monica Riley; Bernard Labedan
Protein evolution viewed through Escherichia coli protein sequences: introducing the notion of a structural segment of homology, the module.
Journal of molecular biology 1997;268(5):857-68.
1997: R Kort; W Liebl; Bernard Labedan; Patrick Forterre; R I Eggen; WILLEM DE VOS
Glutamate dehydrogenase from the hyperthermophilic bacterium Thermotoga maritima: molecular characterization and phylogenetic implications.
Extremophiles : life under extreme conditions 1997;1(1):52-60.
1996: O Guipaud; Bernard Labedan; Patrick Forterre
A gyrB-like gene from the hyperthermophilic bacterion Thermotoga maritima.
Gene 1996;174(1):121-8.
1996: A Bouyoub; G Barbier; Patrick Forterre; Bernard Labedan
The adenylosuccinate synthetase from the hyperthermophilic archaeon Pyrococcus species displays unusual structural features.
Journal of molecular biology 1996;261(2):144-54.
1995: Bernard Labedan; M Riley
Gene products of Escherichia coli: sequence comparisons and common ancestries.
Molecular biology and evolution 1995;12(6):980-7.
1995: Bernard Labedan; M Riley
Widespread protein sequence similarities: origins of Escherichia coli genes.
Journal of bacteriology 1995;177(6):1585-8.
1994: N Benachenhou-Lahfa; Bernard Labedan; Patrick Forterre
PCR-mediated cloning and sequencing of the gene encoding glutamate dehydrogenase from the archaeon Sulfolobus shibatae: identification of putative amino-acid signatures for extremophilic adaptation.
Gene 1994;140(1):17-24.
1993: Patrick Forterre; N Benachenhou-Lafha; Bernard Labedan
Universal tree of life.
Nature 1993;362(6423):795.
1993: N Benachenhou-Lahfa; Patrick Forterre; Bernard Labedan
Evolution of glutamate dehydrogenase genes: evidence for two paralogous protein families and unusual branching patterns of the archaebacteria in the universal tree of life.
Journal of molecular evolution 1993;36(4):335-46.
1992: Patrick Forterre; N Benachenhou-Lahfa; F Confalonieri; Michel Duguet; C Elie; Bernard Labedan
The nature of the last universal ancestor and the root of the tree of life, still open questions.
Bio Systems 1992;28(1-3):15-32.
1988: Bernard Labedan
Increase in permeability of Escherichia coli outer membrane by local anesthetics and penetration of antibiotics.
Antimicrobial agents and chemotherapy 1988;32(1):153-5.