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Claude Labrie

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Nicolas Léveillé; Andréa Fournier; Claude Labrie
Androgens down-regulate myosin light chain kinase in human prostate cancer cells.
Fernand Labrie; Leonello Cusan; José Luis Gomez; Isabelle Côté; René Bérubé; Patrick Bélanger; Céline Martel; Claude Labrie
Effect of one-week treatment with vaginal estrogen preparations on serum estrogen levels in postmenopausal women.
Fernand Labrie; Leonello Cusan; José Luis Gomez; Isabelle Côté; René Bérubé; Patrick Bélanger; Céline Martel; Claude Labrie
Effect of intravaginal DHEA on serum DHEA and eleven of its metabolites in postmenopausal women.

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2009: Nicolas Léveillé; Andréa Fournier; Claude Labrie
Androgens down-regulate myosin light chain kinase in human prostate cancer cells.
The Journal of steroid biochemistry and molecular biology 2009;114(3-5):174-9.
2009: Fernand Labrie; Leonello Cusan; José Luis Gomez; Isabelle Côté; René Bérubé; Patrick Bélanger; Céline Martel; Claude Labrie
Effect of one-week treatment with vaginal estrogen preparations on serum estrogen levels in postmenopausal women.
Menopause (New York, N.Y.) 2009;16(1):30-6.
2008: Fernand Labrie; Leonello Cusan; José Luis Gomez; Isabelle Côté; René Bérubé; Patrick Bélanger; Céline Martel; Claude Labrie
Effect of intravaginal DHEA on serum DHEA and eleven of its metabolites in postmenopausal women.
The Journal of steroid biochemistry and molecular biology 2008;111(3-5):178-94.
2008: Claude Labrie; Julie Lessard; Sonia Ben Aicha; Marie-Paule Savard; Mélissa Pelletier; Andréa Fournier; Eliane Lavergne; Ezequiel Calvo
Androgen-regulated transcription factor AIbZIP in prostate cancer.
The Journal of steroid biochemistry and molecular biology 2008;108(3-5):237-44.
2008: Georges Pelletier; Claude Labrie; Céline Martel; Fernand Labrie
Chronic administration of dehydroepiandrosterone (DHEA) to female monkey and rat has no effect on mammary gland histology.
The Journal of steroid biochemistry and molecular biology 2008;108(1-2):102-8.
2007: Sonia Ben Aicha; Julie Lessard; Mélissa Pelletier; Andréa Fournier; Ezequiel Calvo; Claude Labrie
Transcriptional profiling of genes that are regulated by the endoplasmic reticulum-bound transcription factor AIbZIP/CREB3L4 in prostate cells.
Physiological genomics 2007;31(2):295-305.
2007: Fernand Labrie; Alain Bélanger; Claude Labrie; Bernard Candas; Leonello Cusan; José Luis Gomez
Bioavailability and metabolism of oral and percutaneous dehydroepiandrosterone in postmenopausal women.
The Journal of steroid biochemistry and molecular biology 2007;107(1-2):57-69.
2007: Julie Lessard; Sonia Ben Aicha; Andréa Fournier; Ezequiel Calvo; Eliane Lavergne; Mélissa Pelletier; Claude Labrie
Characterization of the RSL1-dependent conditional expression system in LNCaP prostate cancer cells and development of a single vector format.
The Prostate 2007;67(8):808-19.
2007: Marie-Helene Levesque; Mohamed El-Alfy; Louise Berger; Fernand Labrie; Claude Labrie
Evaluation of AIbZIP and Cdc47 as markers for human prostatic diseases.
Urology 2007;69(1):196-201.
2006: Mohamed El-Alfy; Lamia Azzi; Julie Lessard; Eliane Lavergne; Mélissa Pelletier; Claude Labrie
Stage-specific expression of the Atce1/Tisp40alpha isoform of CREB3L4 in mouse spermatids.
Journal of andrology 2006;27(5):686-94.
2006: Fernand Labrie; Van Luu-The; Céline Martel; Ariel Chernomoretz; Ezequiel Calvo; Jean Morissette; Claude Labrie
Dehydroepiandrosterone (DHEA) is an anabolic steroid like dihydrotestosterone (DHT), the most potent natural androgen, and tetrahydrogestrinone (THG).
The Journal of steroid biochemistry and molecular biology 2006;100(1-3):52-8.
2005: Fernand Labrie; Van Luu-The; Alain Bélanger; Sheng-Xiang Lin; Jacques Simard; Georges Pelletier; Claude Labrie
Is dehydroepiandrosterone a hormone?
The Journal of endocrinology 2005;187(2):169-96.
2005: Fernand Labrie; Alain Bélanger; Van Luu-The; Claude Labrie; Jacques Simard; Leonello Cusan; José Gomez; Bernard Candas
Gonadotropin-releasing hormone agonists in the treatment of prostate cancer.
Endocrine reviews 2005;26(3):361-79.
2005: Fernand Labrie; Van Luu-The; Ezequiel Calvo; Céline Martel; Julie Cloutier; Sylvain Gauthier; Pascal Belleau; Jean Morissette; Marie-Helene Levesque; Claude Labrie
Tetrahydrogestrinone induces a genomic signature typical of a potent anabolic steroid.
The Journal of endocrinology 2005;184(2):427-33.
2004: Fernand Labrie; Leonello Cusan; José Gomez; Van Luu-The; Bernard Candas; Alain Bélanger; Claude Labrie
Major impact of hormonal therapy in localized prostate cancer--death can already be an exception.
The Journal of steroid biochemistry and molecular biology 2004;92(5):327-44.
2004: Carl Bolduc; Marianne Larose; Mayumi Yoshioka; P Ye; Pascal Belleau; Claude Labrie; Jean Morissette; Vincent Raymond; Fernand Labrie; Jonny St-Amand
Effects of dihydrotestosterone on adipose tissue measured by serial analysis of gene expression.
Journal of molecular endocrinology 2004;33(2):429-44.
2004: Marianne Larose; Jonny St-Amand; Mayumi Yoshioka; Pascal Belleau; Jean Morissette; Claude Labrie; Vincent Raymond; Fernand Labrie
Transcriptome of mouse uterus by serial analysis of gene expression (SAGE): comparison with skeletal muscle.
Molecular reproduction and development 2004;68(2):142-8.
2004: Carl Bolduc; Marianne Larose; Nicolas Lafond; Mayumi Yoshioka; Marc-André Rodrigue; Jean Morissette; Claude Labrie; Vincent Raymond; Jonny St-Amand
Adipose tissue transcriptome by serial analysis of gene expression.
Obesity research 2004;12(5):750-7.
2004: Mathias Leblanc; Marie-Claire Bélanger; Pierre Julien; André Tchernof; Claude Labrie; Alain Bélanger; Fernand Labrie
Plasma lipoprotein profile in the male cynomolgus monkey under normal, hypogonadal, and combined androgen blockade conditions.
The Journal of clinical endocrinology and metabolism 2004;89(4):1849-57.
2004: Fernand Labrie; Patrick Champagne; Claude Labrie; Jean Roy; Jacques Laverdière; Louise Provencher; Martin Potvin; Yvan Drolet; Michael Pollak; Lawrence Panasci; Bernard L'Espérance; Jean Dufresne; Jean Latreille; Jean Robert; Benoît Samson; Jacques Jolivet; Louise Yelle; Leonello Cusan; Pierre Diamond; Bernard Candas
Activity and safety of the antiestrogen EM-800, the orally active precursor of acolbifene, in tamoxifen-resistant breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(5):864-71.
2003: Heng Qi; Josée Grenier; Andréa Fournier; Claude Labrie
Androgens differentially regulate the expression of NEDD4L transcripts in LNCaP human prostate cancer cells.
Molecular and cellular endocrinology 2003;210(1-2):51-62.
2003: Fernand Labrie; Mohamed El-Alfy; Louise Berger; Claude Labrie; Céline Martel; Alain Bélanger; Bernard Candas; Georges Pelletier
The combination of a novel selective estrogen receptor modulator with an estrogen protects the mammary gland and uterus in a rodent model: the future of postmenopausal women's health?
Endocrinology 2003;144(11):4700-6.
2003: Fernand Labrie; Leonello Cusan; José Luis Gomez; Bernard Candas; Alain Bélanger; Van Luu-The; Claude Labrie; Jacques Simard
[From the gene to the clinic: prostate cancer death can now be an exception?].
Médecine sciences : M/S 2003;19(10):910-9.
2003: Mathias Leblanc; Claude Labrie; Alain Bélanger; Bernard Candas; Fernand Labrie
Bioavailability and pharmacokinetics of dehydroepiandrosterone in the cynomolgus monkey.
The Journal of clinical endocrinology and metabolism 2003;88(9):4293-302.
2003: Heng Qi; Andréa Fournier; Josée Grenier; Catherine Fillion; Yvan Labrie; Claude Labrie
Isolation of the novel human guanine nucleotide exchange factor Src homology 3 domain-containing guanine nucleotide exchange factor (SGEF) and of C-terminal SGEF, an N-terminally truncated form of SGEF, the expression of which is regulated by androgen in prostate cancer cells.
Endocrinology 2003;144(5):1742-52.
2003: Fernand Labrie; Van Luu-The; Claude Labrie; Alain Bélanger; Jacques Simard; Sheng-Xiang Lin; Georges Pelletier
Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone.
Endocrine reviews 2003;24(2):152-82.
2003: Frédéric Pouliot; Alexandre Blais; Claude Labrie
Overexpression of a dominant negative type II bone morphogenetic protein receptor inhibits the growth of human breast cancer cells.
Cancer research 2003;63(2):277-81.
2003: Mathieu Gutmann; Steeve Couillard; Fernand Labrie; Bernard Candas; Claude Labrie
Effect of treatment sequence with radiotherapy and the antiestrogen EM 800 on the growth of ZR 75 1 human mammary carcinoma in nude mice.
International journal of cancer. Journal international du cancer 2003;103(2):268-76.
2002: Alexandre Blais; didier monte; Frédéric Pouliot; Claude Labrie
Regulation of the human cyclin-dependent kinase inhibitor p18INK4c by the transcription factors E2F1 and Sp1.
The Journal of biological chemistry 2002;277(35):31679-93.
2002: Mathias Leblanc; Claude Labrie; Alain Bélanger; Bernard Candas; Fernand Labrie
Pharmacokinetics of oral dehydroepiandrosterone (DHEA) in the ovariectomised cynomolgus monkey.
The Journal of steroid biochemistry and molecular biology 2002;81(2):159-64.
2002: Mathieu Gutmann; Steeve Couillard; Jenny Roy; Fernand Labrie; Bernard Candas; Claude Labrie
Comparison of the effects of EM-652 (SCH57068), tamoxifen, toremifene, droloxifene, idoxifene, GW-5638 and raloxifene on the growth of human ZR-75-1 breast tumors in nude mice.
International journal of cancer. Journal international du cancer 2002;99(2):273-8.
2002: Heng Qi; Catherine Fillion; Yvan Labrie; Josée Grenier; Andréa Fournier; Louise Berger; Mohamed El-Alfy; Claude Labrie
AIbZIP, a novel bZIP gene located on chromosome 1q21.3 that is highly expressed in prostate tumors and of which the expression is up-regulated by androgens in LNCaP human prostate cancer cells.
Cancer research 2002;62(3):721-33.
2002: Frédéric Pouliot; Claude Labrie
Role of Smad1 and Smad4 proteins in the induction of p21WAF1,Cip1 during bone morphogenetic protein-induced growth arrest in human breast cancer cells.
The Journal of endocrinology 2002;172(1):187-98.
2001: Fernand Labrie; Claude Labrie; Alain Bélanger; Jacques Simard; V Giguère; A Tremblay; G Tremblay
EM-652 (SCH57068), a pure SERM having complete antiestrogenic activity in the mammary gland and endometrium.
The Journal of steroid biochemistry and molecular biology 2001;79(1-5):213-25.
2001: Georges Pelletier; Mohamed El-Alfy; Claude Labrie; Céline Martel; Fernand Labrie
Effect of long-term treatment with the antiestrogen EM-652.HCl on pituitary estrogen receptor alpha and prolactin mRNA expression in intact, ovariectomized and gonadotropin-releasing hormone-treated female rats.
Neuroendocrinology 2001;74(6):367-74.
2001: J Lapointe; Claude Labrie
Role of the cyclin-dependent kinase inhibitor p27(Kip1) in androgen-induced inhibition of CAMA-1 breast cancer cell proliferation.
Endocrinology 2001;142(10):4331-8.
2001: Heng Qi; Yvan Labrie; Josée Grenier; Andréa Fournier; Catherine Fillion; Claude Labrie
Androgens induce expression of SPAK, a STE20/SPS1-related kinase, in LNCaP human prostate cancer cells.
Molecular and cellular endocrinology 2001;182(2):181-92.
2001: Georges Pelletier; Claude Labrie; Céline Martel; S Li; Fernand Labrie
Role of extra-ovarian oestrogens in the regulation of gonadotropin releasing hormone mRNA expression in the rat brain.
Journal of neuroendocrinology 2001;13(8):678-82.
2001: Fernand Labrie; Van Luu-The; Claude Labrie; Jacques Simard
DHEA and its transformation into androgens and estrogens in peripheral target tissues: intracrinology.
Frontiers in neuroendocrinology 2001;22(3):185-212.
2001: Olivier Barbier; C Albert; Isabelle Martineau; Marie-Hélène Vallée; K High; Fernand Labrie; Dean W Hum; Claude Labrie; Alain Bélanger
Glucuronidation of the nonsteroidal antiestrogen EM-652 (SCH 57068), by human and monkey steroid conjugating UDP-glucuronosyltransferase enzymes.
Molecular pharmacology 2001;59(3):636-45.
2001: Fernand Labrie; Claude Labrie; Alain Bélanger; V Giguere; Jacques Simard; Yves Mérand; Sylvain Gauthier; Van Luu-The; Bernard Candas; Céline Martel; S Luo
Pure selective estrogen receptor modulators, new molecules having absolute cell specificity ranging from pure antiestrogenic to complete estrogen-like activities.
Advances in protein chemistry 2001;56():293-368.
2000: Fernand Labrie; Van Luu-The; Sheng-Xiang Lin; Jacques Simard; Claude Labrie
Role of 17 beta-hydroxysteroid dehydrogenases in sex steroid formation in peripheral intracrine tissues.
Trends in endocrinology and metabolism: TEM 2000;11(10):421-7.
2000: A Sourla; V Richard; Fernand Labrie; Claude Labrie
Exclusive androgenic effect of dehydroepiandrosterone in sebaceous glands of rat skin.
The Journal of endocrinology 2000;166(2):455-62.
2000: Fernand Labrie; Van Luu-The; Sheng-Xiang Lin; Jacques Simard; Claude Labrie; Mohamed El-Alfy; Georges Pelletier; Alain Bélanger
Intracrinology: role of the family of 17 beta-hydroxysteroid dehydrogenases in human physiology and disease.
Journal of molecular endocrinology 2000;25(1):1-16.
2000: Georges Pelletier; Claude Labrie; Fernand Labrie
Localization of oestrogen receptor alpha, oestrogen receptor beta and androgen receptors in the rat reproductive organs.
The Journal of endocrinology 2000;165(2):359-70.
2000: Steeve Couillard; Claude Labrie; Sylvain Gauthier; Y Merand; SM Singh; Bernard Candas; Fernand Labrie
Long-term inhibitory effect of the orally active and pure antiestrogen EM-800 on the growth of human breast cancer xenografts in nude mice.
International journal of cancer. Journal international du cancer 2000;85(3):424-9.
2000: Fernand Labrie; Van Luu-The; Claude Labrie; Georges Pelletier; Mohamed El-Alfy
Intracrinology and the skin.
Hormone research 2000;54(5-6):218-29.
1999: Mathieu Gutmann; Steeve Couillard; Fernand Labrie; Bernard Candas; Claude Labrie
Effects of the antiestrogen EM-800 (SCH 57050) and cyclophosphamide alone and in combination on growth of human ZR-75-1 breast cancer xenografts in nude mice.
Cancer research 1999;59(20):5176-80.
1999: Steeve Couillard; Mathieu Gutmann; Fernand Labrie; Bernard Candas; Claude Labrie
Effect of combined treatment with the pure antiestrogen EM-800 and radiotherapy on the growth of human ZR-75-1 breast cancer xenografts in nude mice.
Cancer research 1999;59(19):4857-63.
1999: Fernand Labrie; Claude Labrie; Alain Bélanger; Jacques Simard; Sylvain Gauthier; Van Luu-The; Yves Mérand; V Giguere; Bernard Candas; S Luo; Céline Martel; SM Singh; M Fournier; A Coquet; V Richard; R Charbonneau; G Charpenet; A Tremblay; G Tremblay; Leonello Cusan; R Veilleux
EM-652 (SCH 57068), a third generation SERM acting as pure antiestrogen in the mammary gland and endometrium.
The Journal of steroid biochemistry and molecular biology 1999;69(1-6):51-84.
1999: Frédéric Pouliot; Claude Labrie
Expression profile of agonistic Smads in human breast cancer cells: absence of regulation by estrogens.
International journal of cancer. Journal international du cancer 1999;81(1):98-103.
1999: J Lapointe; A Fournier; V Richard; Claude Labrie
Androgens down-regulate bcl-2 protooncogene expression in ZR-75-1 human breast cancer cells.
Endocrinology 1999;140(1):416-21.
1998: Alexandre Blais; Yvan Labrie; Frédéric Pouliot; Y Lachance; Claude Labrie
Structure of the gene encoding the human cyclin-dependent kinase inhibitor p18 and mutational analysis in breast cancer.
Biochemical and biophysical research communications 1998;247(1):146-53.
1998: Céline Martel; A Sourla; G Pelletier; Claude Labrie; M Fournier; S Picard; Shi-Hua Li; M Stojanovic; Fernand Labrie
Predominant androgenic component in the stimulatory effect of dehydroepiandrosterone on bone mineral density in the rat.
The Journal of endocrinology 1998;157(3):433-42.
1998: Steeve Couillard; Claude Labrie; Alain Bélanger; Bernard Candas; Frédéric Pouliot; Fernand Labrie
Effect of dehydroepiandrosterone and the antiestrogen EM-800 on growth of human ZR-75-1 breast cancer xenografts.
Journal of the National Cancer Institute 1998;90(10):772-8.
1998: S Luo; Claude Labrie; Alain Bélanger; Bernard Candas; Fernand Labrie
Prevention of development of dimethylbenz(a)anthracene (DMBA)-induced mammary tumors in the rat by the new nonsteroidal antiestrogen EM-800 (SCH57050).
Breast cancer research and treatment 1998;49(1):1-11.
1998: Fernand Labrie; Alain Bélanger; Van Luu-The; Claude Labrie; Jacques Simard; Leonello Cusan; José Luis Gomez; Bernard Candas
DHEA and the intracrine formation of androgens and estrogens in peripheral target tissues: its role during aging.
Steroids 1998;63(5-6):322-8.
1998: S Luo; A Sourla; Claude Labrie; Sylvain Gauthier; Y Merand; A Belanger; Fernand Labrie
Effect of twenty-four-week treatment with the antiestrogen EM-800 on estrogen-sensitive parameters in intact and ovariectomized mice.
Endocrinology 1998;139(5):2645-56.
1998: Céline Martel; Claude Labrie; Alain Bélanger; Sylvain Gauthier; Yves Mérand; X Li; Louise Provencher; Bernard Candas; Fernand Labrie
Comparison of the effects of the new orally active antiestrogen EM-800 with ICI 182 780 and toremifene on estrogen-sensitive parameters in the ovariectomized mouse.
Endocrinology 1998;139(5):2486-92.
1998: A Sourla; Céline Martel; Claude Labrie; Fernand Labrie
Almost exclusive androgenic action of dehydroepiandrosterone in the rat mammary gland.
Endocrinology 1998;139(2):753-64.
1998: Steeve Couillard; Mathieu Gutmann; Claude Labrie; Alain Bélanger; Bernard Candas; Fernand Labrie
Comparison of the effects of the antiestrogens EM-800 and tamoxifen on the growth of human breast ZR-75-1 cancer xenografts in nude mice.
Cancer research 1998;58(1):60-4.
1997: S Luo; Céline Martel; C Chen; Claude Labrie; Bernard Candas; S M Singh; Fernand Labrie
Daily dosing with flutamide or Casodex exerts maximal antiandrogenic activity.
Urology 1997;50(6):913-9.
1997: A Sourla; S Luo; Claude Labrie; Alain Bélanger; Fernand Labrie
Morphological changes induced by 6-month treatment of intact and ovariectomized mice with tamoxifen and the pure antiestrogen EM-800.
Endocrinology 1997;138(12):5605-17.
1997: S Luo; Céline Martel; Sylvain Gauthier; Yves Mérand; Alain Bélanger; Claude Labrie; Fernand Labrie
Long-term inhibitory effects of a novel anti-estrogen on the growth of ZR-75-1 and MCF-7 human breast cancer tumors in nude mice.
International journal of cancer. Journal international du cancer 1997;73(5):735-9.
1997: S Luo; M Stojanovic; Claude Labrie; Fernand Labrie
Inhibitory effect of the novel anti-estrogen EM-800 and medroxyprogesterone acetate on estrone-stimulated growth of dimethylbenz[a]anthracene-induced mammary carcinoma in rats.
International journal of cancer. Journal international du cancer 1997;73(4):580-6.
1997: S Luo; Céline Martel; A Sourla; Sylvain Gauthier; Yves Mérand; A Belanger; Claude Labrie; Fernand Labrie
Comparative effects of 28-day treatment with the new anti-estrogen EM-800 and tamoxifen on estrogen-sensitive parameters in intact mice.
International journal of cancer. Journal international du cancer 1997;73(3):381-91.
1997: S Luo; A Sourla; Claude Labrie; Alain Bélanger; Fernand Labrie
Combined effects of dehydroepiandrosterone and EM-800 on bone mass, serum lipids, and the development of dimethylbenz(A)anthracene-induced mammary carcinoma in the rat.
Endocrinology 1997;138(10):4435-44.
1997: Jacques Simard; Claude Labrie; Alain Bélanger; Sylvain Gauthier; SM Singh; Yves Mérand; Fernand Labrie
Characterization of the effects of the novel non-steroidal antiestrogen EM-800 on basal and estrogen-induced proliferation of T-47D, ZR-75-1 and MCF-7 human breast cancer cells in vitro.
International journal of cancer. Journal international du cancer 1997;73(1):104-12.
1997: Jacques Simard; R Sanchez; D Poirier; Sylvain Gauthier; SM Singh; Y Merand; A Belanger; Claude Labrie; Fernand Labrie
Blockade of the stimulatory effect of estrogens, OH-tamoxifen, OH-toremifene, droloxifene, and raloxifene on alkaline phosphatase activity by the antiestrogen EM-800 in human endometrial adenocarcinoma Ishikawa cells.
Cancer research 1997;57(16):3494-7.
1997: S Luo; Claude Labrie; Alain Bélanger; Fernand Labrie
Effect of dehydroepiandrosterone on bone mass, serum lipids, and dimethylbenz(a)anthracene-induced mammary carcinoma in the rat.
Endocrinology 1997;138(8):3387-94.
1997: Sylvain Gauthier; B Caron; Julie Cloutier; Y L Dory; A Favre; D Larouche; J Mailhot; C Ouellet; A Schwerdtfeger; Gilles Leblanc; Céline Martel; Jacques Simard; Yves Mérand; Alain Bélanger; Claude Labrie; Fernand Labrie
(S)-(+)-4-[7-(2,2-dimethyl-1-oxopropoxy)-4-methyl-2-[4-[2-(1-piperidinyl)-ethoxy]phenyl]-2H-1-benzopyran-3-yl]-phenyl 2,2-dimethylpropanoate (EM-800): a highly potent, specific, and orally active nonsteroidal antiestrogen.
Journal of medicinal chemistry 1997;40(14):2117-22.
1997: Fernand Labrie; Van Luu-The; Sheng-Xiang Lin; Claude Labrie; Jacques Simard; Rock Breton; Alain Bélanger
The key role of 17 beta-hydroxysteroid dehydrogenases in sex steroid biology.
Steroids 1997;62(1):148-58.
1996: J Lapointe; Y Lachance; Y Labrie; Claude Labrie
A p18 mutant defective in CDK6 binding in human breast cancer cells.
Cancer research 1996;56(20):4586-9.
1995: Fernand Labrie; Alain Bélanger; Jacques Simard; Claude Labrie
DHEA and peripheral androgen and estrogen formation: intracinology.
Annals of the New York Academy of Sciences 1995;774():16-28.
1995: Y Labrie; Francine Durocher; Y Lachance; C Turgeon; Jacques Simard; Claude Labrie; Fernand Labrie
The human type II 17 beta-hydroxysteroid dehydrogenase gene encodes two alternatively spliced mRNA species.
DNA and cell biology 1995;14(10):849-61.
1995: Fernand Labrie; Shi-Hua Li; Claude Labrie; C Lévesque; Yves Mérand
Inhibitory effect of a steroidal antiestrogen (EM-170) on estrone-stimulated growth of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat.
Breast cancer research and treatment 1995;33(3):237-44.
1993: Céline Martel; C Trudel; J Couet; Claude Labrie; Alain Bélanger; Fernand Labrie
Blockade of androstenedione-induced stimulation of androgen-sensitive parameters in the rat prostate by combination of Flutamide and 4-MA.
Molecular and cellular endocrinology 1993;91(1-2):43-9.
1993: Fernand Labrie; A Belanger; Jacques Simard; Claude Labrie; A Dupont
Combination therapy for prostate cancer. Endocrine and biologic basis of its choice as new standard first-line therapy.
Cancer 1993;71(3 Suppl):1059-67.
1992: Fernand Labrie; Jacques Simard; Van Luu-The; Georges Pelletier; Alain Bélanger; Y Lachance; H F Zhao; Claude Labrie; N Breton; Y de Launoit
Structure and tissue-specific expression of 3 beta-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase genes in human and rat classical and peripheral steroidogenic tissues.
The Journal of steroid biochemistry and molecular biology 1992;41(3-8):421-35.
1992: Y Lachance; Van Luu-The; Claude Labrie; Jacques Simard; M Dumont; Y de Launoit; S Guérin; G Leblanc; Fernand Labrie
Characterization of human 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase gene and its expression in mammalian cells.
The Journal of biological chemistry 1992;267(5):3551.
1992: Claude Labrie; Céline Martel; J M Dufour; C Lévesque; Yves Mérand; Fernand Labrie
Novel compounds inhibit estrogen formation and action.
Cancer research 1992;52(3):610-5.
1991: C Trudel; J Couët; Céline Martel; Claude Labrie; Fernand Labrie
Regulation of adrenal 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase expression and activity by adrenocorticotropin and corticosterone in the rat.
Endocrinology 1991;129(4):2077-84.
1991: Fernand Labrie; Jacques Simard; Van Luu-The; C Trudel; Céline Martel; Claude Labrie; H F Zhao; E Rhéaume; J Couet; N Breton
Expression of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD) and 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD) in adipose tissue.
International journal of obesity 1991;15 Suppl 2():91-9.
1991: Claude Labrie; C Trudel; Shi-Hua Li; Céline Martel; J Couêt; Fernand Labrie
Combination of an antiandrogen and a 5 alpha-reductase inhibitor: a further step towards total androgen blockade?
Endocrinology 1991;129(1):566-8.
1991: Donald Poirier; Claude Labrie; Yves Mérand; Fernand Labrie
Synthesis and biological activity of 17 alpha-alkynylamide derivatives of estradiol.
The Journal of steroid biochemistry and molecular biology 1991;38(6):759-74.
1991: C Levesque; Y Merand; J M Dufour; Claude Labrie; Fernand Labrie
Synthesis and biological activity of new halo-steroidal antiestrogens.
Journal of medicinal chemistry 1991;34(5):1624-30.
1991: H F Zhao; Claude Labrie; Jacques Simard; Y de Launoit; C Trudel; Céline Martel; E Rhéaume; E Dupont; Van Luu-The; Georges Pelletier
Characterization of rat 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase cDNAs and differential tissue-specific expression of the corresponding mRNAs in steroidogenic and peripheral tissues.
The Journal of biological chemistry 1991;266(1):583-93.
1990: Céline Martel; Claude Labrie; E Dupont; J Couet; C Trudel; E Rheaume; Jacques Simard; Van Luu-The; Georges Pelletier; Fernand Labrie
Regulation of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase expression and activity in the hypophysectomized rat ovary: interactions between the stimulatory effect of human chorionic gonadotropin and the luteolytic effect of prolactin.
Endocrinology 1990;127(6):2726-37.
1990: Y Lachance; Van Luu-The; Claude Labrie; Jacques Simard; M Dumont; Y de Launoit; S Guérin; G Leblanc; Fernand Labrie
Characterization of human 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase gene and its expression in mammalian cells.
The Journal of biological chemistry 1990;265(33):20469-75.
1990: Céline Martel; Claude Labrie; J Couët; E Dupont; C Trudel; Van Luu-The; M Takahashi; Georges Pelletier; Fernand Labrie
Effects of human chorionic gonadotropin (hCG) and prolactin (PRL) on 3 beta-hydroxy-5-ene-steroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD) expression and activity in the rat ovary.
Molecular and cellular endocrinology 1990;72(2):R7-13.
1990: Donald Poirier; Claude Labrie; Yves Mérand; Fernand Labrie
Derivatives of ethynylestradiol with oxygenated 17 alpha-alkyl side chain: synthesis and biological activity.
Journal of steroid biochemistry 1990;36(1-2):133-42.
1990: Van Luu-The; Claude Labrie; Jacques Simard; Y Lachance; H F Zhao; J Couët; G Leblanc; Fernand Labrie
Structure of two in tandem human 17 beta-hydroxysteroid dehydrogenase genes.
Molecular endocrinology (Baltimore, Md.) 1990;4(2):268-75.
1990: Claude Labrie; Jacques Simard; H F Zhao; Georges Pelletier; Fernand Labrie
Synthetic progestins stimulate prostatic binding protein messenger RNAs in the rat ventral prostate.
Molecular and cellular endocrinology 1990;68(2-3):169-79.
1990: Fernand Labrie; Jacques Simard; Richard Poulin; A C Hatton; Claude Labrie; S Dauvois; H F Zhao; L Petitclerc; J Couët; M Dumont
Potent antagonism between estrogens and androgens on GCDFP-15 expression and cell growth in the ZR-75-1 human breast cancer cells.
Annals of the New York Academy of Sciences 1990;586():174-87.
1990: Van Luu-The; Claude Labrie; H F Zhao; J Couët; Y Lachance; Jacques Simard; J Côté; G Leblanc; L Lagacé; D Bérubé
Purification, cloning, complementary DNA structure, and predicted amino acid sequence of human estradiol 17 beta-dehydrogenase.
Annals of the New York Academy of Sciences 1990;595():40-52.
1990: Fernand Labrie; Richard Poulin; Jacques Simard; H F Zhao; Claude Labrie; S Dauvois; M Dumont; A C Hatton; Donald Poirier; Yves Mérand
Interactions between estrogens, androgens, progestins, and glucocorticoids in ZR-75-1 human breast cancer cells.
Annals of the New York Academy of Sciences 1990;595():130-48.
1989: H F Zhao; Jacques Simard; Claude Labrie; N Breton; E Rhéaume; Van Luu-The; Fernand Labrie
Molecular cloning, cDNA structure and predicted amino acid sequence of bovine 3 beta-hydroxy-5-ene steroid dehydrogenase/delta 5-delta 4 isomerase.
FEBS letters 1989;259(1):153-7.
1989: D Toranzo; E Dupont; Jacques Simard; Claude Labrie; J Couet; Fernand Labrie; Georges Pelletier
Regulation of pro-gonadotropin-releasing hormone gene expression by sex steroids in the brain of male and female rats.
Molecular endocrinology (Baltimore, Md.) 1989;3(11):1748-56.
1989: Y Tong; Jacques Simard; Claude Labrie; H F Zhao; Fernand Labrie; Georges Pelletier
Inhibitory effect of androgen on estrogen-induced prolactin messenger ribonucleic acid accumulation in the male rat anterior pituitary gland.
Endocrinology 1989;125(4):1821-8.
1989: Van Luu-The; Y Lachance; Claude Labrie; G Leblanc; James Lewis Thomas; R C Strickler; Fernand Labrie
Full length cDNA structure and deduced amino acid sequence of human 3 beta-hydroxy-5-ene steroid dehydrogenase.
Molecular endocrinology (Baltimore, Md.) 1989;3(8):1310-2.
1989: Van Luu-The; Claude Labrie; H F Zhao; J Couët; Y Lachance; Jacques Simard; G Leblanc; J Côté; D Bérubé; R Gagné
Characterization of cDNAs for human estradiol 17 beta-dehydrogenase and assignment of the gene to chromosome 17: evidence of two mRNA species with distinct 5'-termini in human placenta.
Molecular endocrinology (Baltimore, Md.) 1989;3(8):1301-9.
1989: R Poulin; Jacques Simard; Claude Labrie; L Petitclerc; M Dumont; L Lagace; Fernand Labrie
Down-regulation of estrogen receptors by androgens in the ZR-75-1 human breast cancer cell line.
Endocrinology 1989;125(1):392-9.
1989: Claude Labrie; Jacques Simard; H F Zhao; A Belanger; Georges Pelletier; Fernand Labrie
Stimulation of androgen-dependent gene expression by the adrenal precursors dehydroepiandrosterone and androstenedione in the rat ventral prostate.
Endocrinology 1989;124(6):2745-54.
1989: Jacques Simard; A C Hatton; Claude Labrie; S Dauvois; H F Zhao; D E Haagensen; Fernand Labrie
Inhibitory effect of estrogens on GCDFP-15 mRNA levels and secretion in ZR-75-1 human breast cancer cells.
Molecular endocrinology (Baltimore, Md.) 1989;3(4):694-702.
1989: Fernand Labrie; Van Luu-The; Claude Labrie; D Bérubé; J Couet; H F Zhao; R Gagné; Jacques Simard
Characterization of two mRNA species encoding human estradiol 17 beta-dehydrogenase and assignment of the gene to chromosome 17.
Journal of steroid biochemistry 1989;34(1-6):189-97.
1988: Georges Pelletier; Claude Labrie; J Simard; M Duval; M G Martinoli; H Zhao; Fernand Labrie
Effects of sex steroids on regulation of the levels of C1 peptide of rat prostatic steroid-binding protein mRNA evaluated by in-situ hybridization.
Journal of molecular endocrinology 1988;1(3):213-23.
1988: Claude Labrie; A Belanger; Fernand Labrie
Androgenic activity of dehydroepiandrosterone and androstenedione in the rat ventral prostate.
Endocrinology 1988;123(3):1412-7.
1988: Jacques Simard; Claude Labrie; J F Hubert; Fernand Labrie
Modulation by sex steroids and [D-Trp6, Des-Gly-NH2(10)]luteinizing hormone (LH)-releasing hormone ethylamide of alpha-subunit and LH beta messenger ribonucleic acid levels in the rat anterior pituitary gland.
Molecular endocrinology (Baltimore, Md.) 1988;2(9):775-84.
1988: Fernand Labrie; A Dupont; Leonello Cusan; Alain Bélanger; M Giguère; Claude Labrie; Y Lacourcière; G Monfette; J Emond
Combination therapy with flutamide and [D-Trp6, des-Gly-NH2(10)]LHRH ethylamide in stage C and D prostate cancer: today's therapy of choice--rationale and 5-year clinical experience.
Progress in clinical and biological research 1988;262():11-63.
1987: Claude Labrie; Leonello Cusan; M Plante; S Lapointe; Fernand Labrie
Analysis of the androgenic activity of synthetic "progestins" currently used for the treatment of prostate cancer.
Journal of steroid biochemistry 1987;28(4):379-84.
1987: Fernand Labrie; A Dupont; Alain Bélanger; Leonello Cusan; M Giguère; Y Lacourcière; I Luthy; D Bégin; Claude Labrie; J Simard
Combination therapy in stage C and D prostatic cancer: rationale and five year clinical experience.
Cancer metastasis reviews 1987;6(4):615-36.