FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Pedro Miguel Lacal

Research Profile

Chemicals & Drugs

Disorders

Anatomy

Physiology

Living Beings

Mouse

Co-author Network

Publications

TOP 3
Federica Ruffini; C M Failla; Angela Orecchia; M R Bani; A S Dorio; C Fortes; Giovanna Zambruno; Grazia Graziani; R Giavazzi; Stefania D'Atri; Pedro Miguel Lacal
Expression of the soluble vascular endothelial growth factor receptor-1 in cutaneous melanoma: role in tumour progression.
Lauretta Levati; Federica Ruffini; Alessia Muzi; Kazuo Umezawa; Grazia Graziani; Stefania D'Atri; Pedro Miguel Lacal
Placenta growth factor induces melanoma resistance to temozolomide through a mechanism that involves the activation of the transcription factor NF-κB.
Pedro Miguel Lacal; Lucio Tentori; Alessia Muzi; Federica Ruffini; Annalisa Susanna Dorio; Weizheng Xu; Diego Arcelli; Jie Zhang; Grazia Graziani
Pharmacological inhibition of poly(ADP-ribose) polymerase activity down-regulates the expression of syndecan-4 and Id-1 in endothelial cells.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Pedro Miguel Lacal (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2011: Federica Ruffini; C M Failla; Angela Orecchia; M R Bani; A S Dorio; C Fortes; Giovanna Zambruno; Grazia Graziani; R Giavazzi; Stefania D'Atri; Pedro Miguel Lacal
Expression of the soluble vascular endothelial growth factor receptor-1 in cutaneous melanoma: role in tumour progression.
The British journal of dermatology 2011;164(5):1061-70.
2011: Lauretta Levati; Federica Ruffini; Alessia Muzi; Kazuo Umezawa; Grazia Graziani; Stefania D'Atri; Pedro Miguel Lacal
Placenta growth factor induces melanoma resistance to temozolomide through a mechanism that involves the activation of the transcription factor NF-κB.
International journal of oncology 2011;38(1):241-7.
2009: Pedro Miguel Lacal; Lucio Tentori; Alessia Muzi; Federica Ruffini; Annalisa Susanna Dorio; Weizheng Xu; Diego Arcelli; Jie Zhang; Grazia Graziani
Pharmacological inhibition of poly(ADP-ribose) polymerase activity down-regulates the expression of syndecan-4 and Id-1 in endothelial cells.
International journal of oncology 2009;34(3):861-72.
2008: Pedro Miguel Lacal; Veronica Morea; Federica Ruffini; Angela Orecchia; Annalisa S Dorio; Cristina M Failla; Simonetta Soro; Lucio Tentori; Giovanna Zambruno; Grazia Graziani; Anna Tramontano; Stefania D'Atri
Inhibition of endothelial cell migration and angiogenesis by a vascular endothelial growth factor receptor-1 derived peptide.
European journal of cancer (Oxford, England : 1990) 2008;44(13):1914-21.
2008: Lucio Tentori; Alessia Muzi; Annalisa Susanna Dorio; Stefano Bultrini; Emanuela Mazzon; Pedro Miguel Lacal; Girish M Shah; Jie Zhang; Pierluigi Navarra; Giuseppe Nocentini; Salvatore Cuzzocrea; Grazia Graziani
Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity.
European journal of cancer (Oxford, England : 1990) 2008;44(9):1302-14.
2008: Lucio Tentori; Annalisa Susanna Dorio; Alessia Muzi; Pedro Miguel Lacal; Federica Ruffini; Pierluigi Navarra; Grazia Graziani
The integrin antagonist cilengitide increases the antitumor activity of temozolomide against malignant melanoma.
Oncology reports 2008;19(4):1039-43.
2008: Simonetta Soro; Angela Orecchia; Lucia Morbidelli; Pedro Miguel Lacal; Veronica Morea; Kurt Ballmer-Hofer; Federica Ruffini; Marina Ziche; Stefania D'Atri; Giovanna Zambruno; Anna Tramontano; Cristina Maria Failla
A proangiogenic peptide derived from vascular endothelial growth factor receptor-1 acts through alpha5beta1 integrin.
Blood 2008;111(7):3479-88.
2007: Lucio Tentori; Pedro Miguel Lacal; Alessia Muzi; Annalisa Susanna Dorio; Carlo Leonetti; Marco Scarsella; Federica Ruffini; Weizheng Xu; Wokee Min; Antonella Stoppacciaro; Cristina Colarossi; Zhao-Qi Wang; Jie Zhang; Grazia Graziani
Poly(ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis.
European journal of cancer (Oxford, England : 1990) 2007;43(14):2124-33.
2006: Francesca Cianfarani; Giovanna Zambruno; Laura Brogelli; Francesco Sera; Pedro Miguel Lacal; Maurizio Pesce; Maurizio C Capogrossi; Cristina Maria Failla; Monica Napolitano; Teresa Odorisio
Placenta growth factor in diabetic wound healing: altered expression and therapeutic potential.
The American journal of pathology 2006;169(4):1167-82.
2006: Ester Alvino; Daniele Castiglia; simona caporali; Rita Pepponi; Patrizia Caporaso; Pedro Miguel Lacal; Giancarlo Marra; Franziska Fischer; Giovanna Zambruno; Enzo Bonmassar; Josef Jiricny; Stefania D'Atri
A single cycle of treatment with temozolomide, alone or combined with O(6)-benzylguanine, induces strong chemoresistance in melanoma cell clones in vitro: role of O(6)-methylguanine-DNA methyltransferase and the mismatch repair system.
International journal of oncology 2006;29(4):785-97.
2006: Marcella Marcellini; Naomi De Luca; Teresa Riccioni; Alessandro Ciucci; Angela Orecchia; Pedro Miguel Lacal; Federica Ruffini; Maurizio Pesce; Francesca Cianfarani; Giovanna Zambruno; Augusto Orlandi; Cristina Maria Failla
Increased melanoma growth and metastasis spreading in mice overexpressing placenta growth factor.
The American journal of pathology 2006;169(2):643-54.
2005: Lucio Tentori; Carlo Leonetti; Marco Scarsella; Alessia Muzi; Matteo Vergati; Olindo Forini; Pedro Miguel Lacal; Federica Ruffini; Barry Gold; Weixing Li; Jie Zhang; Grazia Graziani
Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide.
European journal of cancer (Oxford, England : 1990) 2005;41(18):2948-57.
2005: Pedro Miguel Lacal; Federica Ruffini; Elena Pagani; Stefania D'Atri
An autocrine loop directed by the vascular endothelial growth factor promotes invasiveness of human melanoma cells.
International journal of oncology 2005;27(6):1625-32.
2005: Lucio Tentori; Matteo Vergati; Alessia Muzi; Lauretta Levati; Federica Ruffini; Olindo Forini; Patrizia Vernole; Pedro Miguel Lacal; Grazia Graziani
Generation of an immortalized human endothelial cell line as a model of neovascular proliferating endothelial cells to assess chemosensitivity to anticancer drugs.
International journal of oncology 2005;27(2):525-35.
2004: graziella pellegrini; Elena Dellambra; Patrizia Paterna; Osvaldo Golisano; Carlo E Traverso; Paolo Rama; Pedro Miguel Lacal; Michele De Luca
Telomerase activity is sufficient to bypass replicative senescence in human limbal and conjunctival but not corneal keratinocytes.
European journal of cell biology 2004;83(11-12):691-700.
2004: Laura Bonmassar; Maria Chiara Massara; Andrea Cottarelli; Angelo Aquino; Vincenzo Formica; Salvatore Pasquale Prete; Pedro Miguel Lacal; P Marchetti; Francesco Concolino; Isabella Faraoni; Stefania D'Atri
Preclinical studies on detection of circulating melanoma cells in patients: telomerase as a recognition marker of malignancy.
Journal of chemotherapy (Florence, Italy) 2004;16(5):479-86.
2003: Angela Orecchia; Pedro Miguel Lacal; Cataldo Schietroma; Veronica Morea; Giovanna Zambruno; Cristina Maria Failla
Vascular endothelial growth factor receptor-1 is deposited in the extracellular matrix by endothelial cells and is a ligand for the alpha 5 beta 1 integrin.
Journal of cell science 2003;116(Pt 17):3479-89.
2003: Cataldo Schietroma; Francesca Cianfarani; Pedro Miguel Lacal; Teresa Odorisio; Angela Orecchia; Jean Kanitakis; Stefania D'Atri; Cristina Maria Failla; Giovanna Zambruno
Vascular endothelial growth factor-C expression correlates with lymph node localization of human melanoma metastases.
Cancer 2003;98(4):789-97.
2003: Elena Pagani; Rita Pepponi; Maria Pia Fuggetta; Salvatore Pasquale Prete; Mario Turriziani; Laura Bonmassar; Pedro Miguel Lacal; Sabrina Falcinelli; F Passarelli; Fiorella Guadagni; Ester Alvino; Stefania D'Atri
DNA repair enzymes and cytotoxic effects of temozolomide: comparative studies between tumor cells and normal cells of the immune system.
Journal of chemotherapy (Florence, Italy) 2003;15(2):173-83.
2001: Rita Pepponi; Grazia Graziani; Sabrina Falcinelli; Patrizia Vernole; Lauretta Levati; Pedro Miguel Lacal; Elena Pagani; Enzo Bonmassar; Josef Jiricny; Stefania D'Atri
hMSH3 overexpression and cellular response to cytotoxic anticancer agents.
Carcinogenesis 2001;22(8):1131-7.
2000: Pedro Miguel Lacal; Cristina Maria Failla; Elena Pagani; Teresa Odorisio; Cataldo Schietroma; Sabrina Falcinelli; Giovanna Zambruno; Stefania D'Atri
Human melanoma cells secrete and respond to placenta growth factor and vascular endothelial growth factor.
The Journal of investigative dermatology 2000;115(6):1000-7.
2000: Lucio Tentori; Patrizia Vernole; Pedro Miguel Lacal; R Madaio; Ilaria Portarena; Lauretta Levati; Alessandra Balduzzi; Mario Turriziani; Prasad Dande; Barry Gold; Enzo Bonmassar; Grazia Graziani
Cytotoxic and clastogenic effects of a DNA minor groove binding methyl sulfonate ester in mismatch repair deficient leukemic cells.
Leukemia 2000;14(8):1451-9.
2000: Stefania D'Atri; Grazia Graziani; Pedro Miguel Lacal; V Nisticò; S Gilberti; Isabella Faraoni; A J Watson; Enzo Bonmassar; G P Margison
Attenuation of O(6)-methylguanine-DNA methyltransferase activity and mRNA levels by cisplatin and temozolomide in jurkat cells.
The Journal of pharmacology and experimental therapeutics 2000;294(2):664-71.
2000: Elena Dellambra; Osvaldo Golisano; Sergio Bondanza; E Siviero; Pedro Miguel Lacal; M Molinari; S D'Atri; Michele De Luca
Downregulation of 14-3-3sigma prevents clonal evolution and leads to immortalization of primary human keratinocytes.
The Journal of cell biology 2000;149(5):1117-30.
1999: Ester Alvino; Rita Pepponi; Elena Pagani; Pedro Miguel Lacal; C Nunziata; Enzo Bonmassar; Stefania D'Atri
O(6)-benzylguanine enhances the in vitro immunotoxic activity of temozolomide on natural or antigen-dependent immunity.
The Journal of pharmacology and experimental therapeutics 1999;291(3):1292-300.
1999: Ruben D Ramirez; Stefania D'Atri; E Pagani; T Faraggiana; Pedro Miguel Lacal; RS Taylor; Jerry W Shay
Progressive increase in telomerase activity from benign melanocytic conditions to malignant melanoma.
Neoplasia (New York, N.Y.) 1999;1(1):42-9.
1998: Lauretta Levati; Giancarlo Marra; T Lettieri; Stefania D'Atri; Patrizia Vernole; Lucio Tentori; Pedro Miguel Lacal; Elena Pagani; Enzo Bonmassar; Josef Jiricny; Grazia Graziani
Mutation of the mismatch repair gene hMSH2 and hMSH6 in a human T-cell leukemia line tolerant to methylating agents.
Genes, chromosomes & cancer 1998;23(2):159-66.
1998: Stefania D'Atri; Lucio Tentori; Pedro Miguel Lacal; Grazia Graziani; Elena Pagani; E Benincasa; Giovanna Zambruno; Enzo Bonmassar; Josef Jiricny
Involvement of the mismatch repair system in temozolomide-induced apoptosis.
Molecular pharmacology 1998;54(2):334-41.
1998: Lucio Tentori; Pedro Miguel Lacal; E Benincasa; D Franco; Isabella Faraoni; Enzo Bonmassar; Grazia Graziani
Role of wild-type p53 on the antineoplastic activity of temozolomide alone or combined with inhibitors of poly(ADP-ribose) polymerase.
The Journal of pharmacology and experimental therapeutics 1998;285(2):884-93.
1997: Lucio Tentori; Laura Orlando; Pedro Miguel Lacal; E Benincasa; Isabella Faraoni; Enzo Bonmassar; Stefania D'Atri; Grazia Graziani
Inhibition of O6-alkylguanine DNA-alkyltransferase or poly(ADP-ribose) polymerase increases susceptibility of leukemic cells to apoptosis induced by temozolomide.
Molecular pharmacology 1997;52(2):249-58.
1996: Pedro Miguel Lacal; Stefania D'Atri; Laura Orlando; Enzo Bonmassar; Grazia Graziani
In vitro inactivation of human O6-alkylguanine DNA alkyltransferase by antitumor triazene compounds.
The Journal of pharmacology and experimental therapeutics 1996;279(1):416-22.
1995: Lucio Tentori; Grazia Graziani; S Gilberti; Pedro Miguel Lacal; Enzo Bonmassar; Stefania D'Atri
Triazene compounds induce apoptosis in O6-alkylguanine-DNA alkyltransferase deficient leukemia cell lines.
Leukemia 1995;9(11):1888-95.
1994: Pedro Miguel Lacal; Carla Amici; Enzo Bonmassar; C D'Onofrio
Effects of cyclopentenone prostaglandins on myeloid cells during early infection with HTLV-I. II. Regulation of synthesis of inducible p72 heat shock protein.
The Journal of pharmacology and experimental therapeutics 1994;271(2):1096-102.
1994: Pedro Miguel Lacal; A Puglianiello; Enzo Bonmassar; C D'Onofrio
Effects of cyclopentenone prostaglandins on myeloid cells during early infection with HTLV-I. I. Cell differentiation determines sensitivity to prostaglandins and virus infection.
The Journal of pharmacology and experimental therapeutics 1994;271(2):1086-95.
1994: G Pistritto; L Ventura; Nadia Mores; Pedro Miguel Lacal; C D'Onofrio
Regulation of PDGF-B and PDGF receptor expression in the pathogenesis of Kaposi's sarcoma in AIDS.
Antibiotics and chemotherapy 1994;46():73-87.