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Burkhard Lachmann

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Haitsma J J; Lachmann B; Papadakos P J
Additives in intravenous anesthesia modulate pulmonary inflammation in a model of LPS-induced respiratory distress.
van der Kaaij Niels P; Kluin Jolanda; Haitsma Jack J; den Bakker Michael A; Lambrecht Bart N; Lachmann Burkhard; de Bruin Ron W F; Bogers Ad J J C
Surfactant pretreatment decreases long-term damage after ischemia-reperfusion injury of the lung.
Schachtrup Christian; Malcharek Stefan; Haitsma Jack J; Lachmann Burkhard; Owada Yuji; Binas Bert; Kondo Hisatake; Rüstow Bernd; Galla Hans-Joachim; Spener Friedrich
Activation of PPARgamma reverses a defect of surfactant synthesis in mice lacking two types of fatty acid binding protein.

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All Publications

2009: Haitsma J J; Lachmann B; Papadakos P J
Additives in intravenous anesthesia modulate pulmonary inflammation in a model of LPS-induced respiratory distress.
Acta anaesthesiologica Scandinavica 2009;53(2):176-82.
2009: van der Kaaij Niels P; Kluin Jolanda; Haitsma Jack J; den Bakker Michael A; Lambrecht Bart N; Lachmann Burkhard; de Bruin Ron W F; Bogers Ad J J C
Surfactant pretreatment decreases long-term damage after ischemia-reperfusion injury of the lung.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2009;35(2):304-12; discussion 312.
2008: Schachtrup Christian; Malcharek Stefan; Haitsma Jack J; Lachmann Burkhard; Owada Yuji; Binas Bert; Kondo Hisatake; Rüstow Bernd; Galla Hans-Joachim; Spener Friedrich
Activation of PPARgamma reverses a defect of surfactant synthesis in mice lacking two types of fatty acid binding protein.
Biochimica et biophysica acta 2008;1781(6-7):314-20.
2008: von Bismarck Philipp; Wistädt Carlos-Francisco García; Klemm Karsten; Winoto-Morbach Supandi; Uhlig Ulrike; Schütze Stefan; Adam Dieter; Lachmann Burkhard; Uhlig Stefan; Krause Martin F
Improved pulmonary function by acid sphingomyelinase inhibition in a newborn piglet lavage model.
American journal of respiratory and critical care medicine 2008;177(11):1233-41.
2008: van der Kaaij Niels P; Kluin Jolanda; Haitsma Jack J; den Bakker Michael A; Lambrecht Bart N; Lachmann Burkhard; de Bruin Ron W F; Bogers Ad J J C
Ischemia of the lung causes extensive long-term pulmonary injury: an experimental study.
Respiratory research 2008;9():28.
2007: von Bismarck Philipp; Klemm Karsten; Wistädt Carlos-Francisco García; Winoto-Morbach Supandi; Uhlig Ulrike; Schütze Stefan; Uhlig Stefan; Lachmann Burkhard; Krause Martin F
Surfactant "fortification" by topical inhibition of nuclear factor-kappaB activity in a newborn piglet lavage model.
Critical care medicine 2007;35(10):2309-18.
2007: Lachmann Robert A; van Kaam Anton H; Haitsma Jack J; Lachmann Burkhard
High positive end-expiratory pressure levels promote bacterial translocation in experimental pneumonia.
Intensive care medicine 2007;33(10):1800-4.
2007: Miranda Dinis Reis; Gommers Diederik; Papadakos Peter J; Lachmann Burkhard
Mechanical ventilation affects pulmonary inflammation in cardiac surgery patients: the role of the open-lung concept.
Journal of cardiothoracic and vascular anesthesia 2007;21(2):279-84.
2007: Papadakos Peter J; Lachmann Burkhard
The open lung concept of mechanical ventilation: the role of recruitment and stabilization.
Critical care clinics 2007;23(2):241-50, ix-x.
2007: Poelma D L; Walther F J; Waring A J; Haitsma J J; Zimmermann L J; Lachmann B; van Iwaarden J F
Effect of SP-B peptides on the uptake of liposomes by alveolar cells.
Neonatology 2007;91(4):233-40.
2006: Lachmann R A; Werchan S; Schachtrup C; Haitsma J J; Spener F; Lachmann B
Liver-type fatty acid binding protein in serum and broncho-alveolar lavage in a model of acute respiratory failure because of surfactant depletion--a possible marker for lung damage?
Clinical physiology and functional imaging 2006;26(6):371-5.
2006: Gommers D; Haitsma J J; Lachmann B
Surfactant as a carrier: influence of immunosuppressive agents on surfactant activity.
Clinical physiology and functional imaging 2006;26(6):357-61.
2006: van Veenendaal Mariëtte B; van Kaam Anton H; Haitsma Jack J; Lutter René; Lachmann Burkhard
Open lung ventilation preserves the response to delayed surfactant treatment in surfactant-deficient newborn piglets.
Critical care medicine 2006;34(11):2827-34.
2006: Reis Miranda Dinis; Klompe Lennart; Mekel Joris; Struijs Ard; van Bommel Jasper; Lachmann Burkhard; Bogers Ad J J C; Gommers Diederik
Open lung ventilation does not increase right ventricular outflow impedance: An echo-Doppler study.
Critical care medicine 2006;34(10):2555-60.
2006: Houmes R-J; Lachmann R A; Haitsma J J; Lachmann B
Small-dose perfluorocarbon reduces the recruitment pressure needed to open surfactant-deficient atelectatic lungs.
Acta anaesthesiologica Scandinavica 2006;50(5):586-92.
2006: Becker Martin J; De Marie Siem; Fens Marcel H A M; Haitsma Jack J; Verbrugh Henri A; Lachmann Burkhard; Bakker-Woudenberg Irma A J M
Pathophysiology of unilateral pulmonary aspergillosis in an experimental rat model.
Medical mycology : official publication of the International Society for Human and Animal Mycology 2006;44(2):133-9.
2006: Haitsma J J; Lachmann B
Lung protective ventilation in ARDS: the open lung maneuver.
Minerva anestesiologica 2006;72(3):117-32.
2006: Miranda Dinis Reis; Klompe Lennart; Cademartiri Filippo; Haitsma Jack J; Palumbo Alessandro; Takkenberg Johanna J M; Lachmann Burkhard; Bogers Ad J J C; Gommers Diederik
The effect of open lung ventilation on right ventricular and left ventricular function in lung-lavaged pigs.
Critical care (London, England) 2006;10(3):R86.
2005: Reis Miranda Dinis; Gommers Diederik; Struijs Ard; Dekker Rien; Mekel Joris; Feelders Richard; Lachmann Burkhard; Bogers Ad J J C
Ventilation according to the open lung concept attenuates pulmonary inflammatory response in cardiac surgery.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2005;28(6):889-95.
2005: Reis Miranda Dinis; Struijs Ard; Koetsier Peter; van Thiel Robert; Schepp Ronald; Hop Wim; Klein Jan; Lachmann Burkhard; Bogers Ad J J C; Gommers Diederik
Open lung ventilation improves functional residual capacity after extubation in cardiac surgery.
Critical care medicine 2005;33(10):2253-8.
2005: van Kaam A H L C; Lutter R; Lachmann R A; Haitsma J J; Herting E; Snoek M; De Jaegere A; Kok J H; Lachmann B
Effect of ventilation strategy and surfactant on inflammation in experimental pneumonia.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2005;26(1):112-7.
2005: van der Kaaij Niels P; Haitsma Jack J; Kluin Jolanda; Lambrecht Bart N; Lachmann Burkhard; de Bruin Ron W F; Bogers Ad J J C
Surfactant pretreatment ameliorates ischemia-reperfusion injury of the lung.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2005;27(5):774-82.
2005: Poelma D L H; Lachmann B; Haitsma J J; Zimmermann L J; van Iwaarden J F
Influence of phosphatidylglycerol on the uptake of liposomes by alveolar cells and on lung function.
Journal of applied physiology (Bethesda, Md. : 1985) 2005;98(5):1784-91.
2005: van Hulst Robert A; Drenthen Judith; Haitsma Jack J; Lameris Thomas W; Visser Gerhard H; Klein Jan; Lachmann Burkhard
Effects of hyperbaric treatment in cerebral air embolism on intracranial pressure, brain oxygenation, and brain glucose metabolism in the pig.
Critical care medicine 2005;33(4):841-6.
2004: Poelma D L H; Zimmermann L J; van Cappellen W A; Haitsma J J; Lachmann B; van Iwaarden J F
Distinct effects of SP-B and SP-C on the uptake of surfactant-like liposomes by alveolar cells in vivo and in vitro.
American journal of physiology. Lung cellular and molecular physiology 2004;287(5):L1056-65.
2004: Reis Miranda D; Gommers D; Struijs A; Meeder H; Schepp R; Hop W; Bogers A; Klein J; Lachmann B
The open lung concept: effects on right ventricular afterload after cardiac surgery.
British journal of anaesthesia 2004;93(3):327-32.
2004: van Hulst R A; Lameris T W; Haitsma J J; Klein J; Lachmann B
Brain glucose and lactate levels during ventilator-induced hypo- and hypercapnia.
Clinical physiology and functional imaging 2004;24(4):243-8.
2004: Lachmann R A; van Kaam A H L C; Haitsma J J; Verbrugge S J C; Delreu F; Lachmann B
Immunoglobulin M-enriched intravenous polyclonal immunoglobulins reduce bacteremia following Klebsiella pneumoniae infection in an acute respiratory distress syndrome rat model.
Experimental lung research 2004;30(4):251-60.
2004: van Kaam Anton H; Lachmann Robert A; Herting Egbert; De Jaegere Anne; van Iwaarden Freek; Noorduyn L Arnold; Kok Joke H; Haitsma Jack J; Lachmann Burkhard
Reducing atelectasis attenuates bacterial growth and translocation in experimental pneumonia.
American journal of respiratory and critical care medicine 2004;169(9):1046-53.
2004: van Hulst Robert A; Haitsma Jack J; Lameris Thomas W; Klein Jan; Lachmann Burkhard
Hyperventilation impairs brain function in acute cerebral air embolism in pigs.
Intensive care medicine 2004;30(5):944-50.
2004: Poelma Davey L; Ju Michel R; Bakker Sjoerd C; Zimmermann Luc J; Lachmann Burkhard F; van Iwaarden J Freek
A common pathway for the uptake of surfactant lipids by alveolar cells.
American journal of respiratory cell and molecular biology 2004;30(5):751-8.
2004: van Kaam Anton H; Haitsma Jack J; Dik Willem A; Naber Birgitta A; Alblas Elise H; De Jaegere Anne; Kok Joke H; Lachmann Burkhard
Response to exogenous surfactant is different during open lung and conventional ventilation.
Critical care medicine 2004;32(3):774-80.
2004: Haitsma Jack J; Papadakos Peter J; Lachmann Burkhard
Surfactant therapy for acute lung injury/acute respiratory distress syndrome.
Current opinion in critical care 2004;10(1):18-22.
2004: van Kaam Anton H; Haitsma Jack J; De Jaegere Anne; van Aalderen Wim M; Kok Joke H; Lachmann Burkhard
Open lung ventilation improves gas exchange and attenuates secondary lung injury in a piglet model of meconium aspiration.
Critical care medicine 2004;32(2):443-9.
2004: Uhlig Ulrike; Fehrenbach Heinz; Lachmann Robert A; Goldmann Torsten; Lachmann Burkhard; Vollmer Ekkehard; Uhlig Stefan
Phosphoinositide 3-OH kinase inhibition prevents ventilation-induced lung cell activation.
American journal of respiratory and critical care medicine 2004;169(2):201-8.
2003: Haitsma Jack J; Lachmann Robert A; Lachmann Burkhard
Open lung in ARDS.
Acta pharmacologica Sinica 2003;24(12):1304-7.
2003: Haitsma Jack J; Uhlig Stefan; Verbrugge Serge J; Göggel Rolf; Poelma Davey L H; Lachmann Burkhard
Injurious ventilation strategies cause systemic release of IL-6 and MIP-2 in rats in vivo.
Clinical physiology and functional imaging 2003;23(6):349-53.
2003: van Hulst Robert A; Klein Jan; Lachmann Burkhard
Gas embolism: pathophysiology and treatment.
Clinical physiology and functional imaging 2003;23(5):237-46.
2003: van Hulst R A; Lameris T W; Hasan D; Klein J; Lachmann B
Effects of cerebral air embolism on brain metabolism in pigs.
Acta neurologica Scandinavica 2003;108(2):118-24.
2003: Drenthen Judith; van Hulst Robert A; Blok Joleen H; van Heel Michiel Dudok; Haitsma Jack J; Lachmann Burkhard; Visser Gerhard H
Quantitative EEG monitoring during cerebral air embolism and hyperbaric oxygen treatment in a pig model.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society 2003;20(4):264-72.
2003: Larsson Marcus; van Iwaarden J Freek; Haitsma Jack J; Lachmann Burkhard; Wollmer Per
Human SP-A and a pharmacy-grade porcine lung surfactant extract can be reconstituted into tubular myelin--a comparative structural study of alveolar surfactants using cryo-transmission electron microscopy.
Clinical physiology and functional imaging 2003;23(4):199-203.
2003: van Hulst Robert A; Haitsma Jack J; Klein Jan; Lachmann Burkhard
Oxygen tension under hyperbaric conditions in healthy pig brain.
Clinical physiology and functional imaging 2003;23(3):143-8.
2003: Haitsma J J; Lachmann R A; Lachmann B
Lung protective ventilation in ARDS: role of mediators, PEEP and surfactant.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo 2003;59(2):108-18.
2003: van Kaam Anton H; de Jaegere Anne; Haitsma Jack J; Van Aalderen Wim M; Kok Joke H; Lachmann Burkhard
Positive pressure ventilation with the open lung concept optimizes gas exchange and reduces ventilator-induced lung injury in newborn piglets.
Pediatric research 2003;53(2):245-53.
2003: Tusman Gerardo; Böhm Stephan H; Tempra Alejandro; Melkun Fernando; García Eduardo; Turchetto Elsio; Mulder Paul G H; Lachmann Burkhard
Effects of recruitment maneuver on atelectasis in anesthetized children.
Anesthesiology 2003;98(1):14-22.
2003: van Kaam Anton H; Dik Willem A; Haitsma Jack J; De Jaegere Anne; Naber Birgitta A; van Aalderen Wim M; Kok Joke H; Lachmann Burkhard
Application of the open-lung concept during positive-pressure ventilation reduces pulmonary inflammation in newborn piglets.
Biology of the neonate 2003;83(4):273-80.
2002: Uhlig U; Haitsma J J; Goldmann T; Poelma D L; Lachmann B; Uhlig S
Ventilation-induced activation of the mitogen-activated protein kinase pathway.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2002;20(4):946-56.
2002: Lachmann B
Open Lung in ARDS.
Minerva anestesiologica 2002;68(9):637-42; discussion 640, 643.
2002: Poelma D L H; Zimmermann L J I; Scholten H H; Lachmann B; van Iwaarden J F
In vivo and in vitro uptake of surfactant lipids by alveolar type II cells and macrophages.
American journal of physiology. Lung cellular and molecular physiology 2002;283(3):L648-54.
2002: Haitsma Jack J; Uhlig Stefan; Lachmann Ulrike; Verbrugge Serge J; Poelma Davey L H; Lachmann Burkhard
Exogenous surfactant reduces ventilator-induced decompartmentalization of tumor necrosis factor alpha in absence of positive end-expiratory pressure.
Intensive care medicine 2002;28(8):1131-7.
2002: Hazebroek E J; Haitsma J J; Lachmann B; Steyerberg E W; de Bruin R W F; Bouvy N D; Bonjer H J
Impact of carbon dioxide and helium insufflation on cardiorespiratory function during prolonged pneumoperitoneum in an experimental rat model.
Surgical endoscopy 2002;16(7):1073-8.
2002: Hazebroek E J; Haitsma J J; Lachmann B; Bonjer H J
Mechanical ventilation with positive end-expiratory pressure preserves arterial oxygenation during prolonged pneumoperitoneum.
Surgical endoscopy 2002;16(4):685-9.
2002: Larsson Marcus; Haitsma Jack J; Lachmann Burkhard; Larsson Kåre; Nylander Tommy; Wollmer Per
Enhanced efficacy of porcine lung surfactant extract by utilization of its aqueous swelling dynamics.
Clinical physiology and functional imaging 2002;22(1):39-48.
2002: Papadakos Peter J; Lachmann Burkhard
The open lung concept of alveolar recruitment can improve outcome in respiratory failure and ARDS.
The Mount Sinai journal of medicine, New York 2002;69(1-2):73-7.
2002: van Hulst Robert A; Hasan Djo; Lachmann Burkhard
Intracranial pressure, brain PCO2, PO2, and pH during hypo- and hyperventilation at constant mean airway pressure in pigs.
Intensive care medicine 2002;28(1):68-73.
2001: Vazquez de Anda G F; Lachmann R A; Verbrugge S J; Gommers D; Haitsma J J; Lachmann B
Partial liquid ventilation improves lung function in ventilation-induced lung injury.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2001;18(1):93-9.
2001: Haitsma J J; Lachmann U; Lachmann B
Exogenous surfactant as a drug delivery agent.
Advanced drug delivery reviews 2001;47(2-3):197-207.
2001: Vazquez de Anda G F; Lachmann R A; Gommers D; Verbrugge S J; Haitsma J; Lachmann B
Treatment of ventilation-induced lung injury with exogenous surfactant.
Intensive care medicine 2001;27(3):559-65.
2001: de Anda G F; Lachmann B
Treatment and prevention of acute respiratory failure: physiological basis.
Archives of medical research 2001;32(2):91-101.
2000: Kunst P W; Vazquez de Anda G; Böhm S H; Faes T J; Lachmann B; Postmus P E; de Vries P M
Monitoring of recruitment and derecruitment by electrical impedance tomography in a model of acute lung injury.
Critical care medicine 2000;28(12):3891-5.
2000: Hartog A; Gommers D; Haitsma J J; Lachmann B
Improvement of lung mechanics by exogenous surfactant: effect of prior application of high positive end-expiratory pressure.
British journal of anaesthesia 2000;85(5):752-6.
2000: Haitsma J J; Uhlig S; Göggel R; Verbrugge S J; Lachmann U; Lachmann B
Ventilator-induced lung injury leads to loss of alveolar and systemic compartmentalization of tumor necrosis factor-alpha.
Intensive care medicine 2000;26(10):1515-22.
2000: Vazquez de Anda G F; Gommers D; Verbrugge S J; De Jaegere A; Lachmann B
Mechanical ventilation with high positive end-expiratory pressure and small driving pressure amplitude is as effective as high-frequency oscillatory ventilation to preserve the function of exogenous surfactant in lung-lavaged rats.
Critical care medicine 2000;28(8):2921-5.
2000: Krause M F; Orlowska-Volk M; Hendrik E R; Gommers D; Lachmann B
A new simple method of staining exogenous surfactant in experimental research.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2000;15(5):949-54.
2000: Hartog A; Vazquez de Anda G F; Gommers D; Kaisers U; Lachmann B
At surfactant deficiency, application of "the open lung concept" prevents protein leakage and attenuates changes in lung mechanics.
Critical care medicine 2000;28(5):1450-4.
2000: Kunst P W; Böhm S H; Vazquez de Anda G; Amato M B; Lachmann B; Postmus P E; de Vries P M
Regional pressure volume curves by electrical impedance tomography in a model of acute lung injury.
Critical care medicine 2000;28(1):178-83.
1999: Verbrugge S J; Gommers D; Lachmann B
Conventional ventilation modes with small pressure amplitudes and high positive end-expiratory pressure levels optimize surfactant therapy.
Critical care medicine 1999;27(12):2724-8.
1999: Verbrugge S J; Uhlig S; Neggers S J; Martin C; Held H D; Haitsma J J; Lachmann B
Different ventilation strategies affect lung function but do not increase tumor necrosis factor-alpha and prostacyclin production in lavaged rat lungs in vivo.
Anesthesiology 1999;91(6):1834-43.
1999: Gommers D; Hartog A; Schnabel R; De Jaegere A; Lachmann B
High-frequency oscillatory ventilation is not superior to conventional mechanical ventilation in surfactant-treated rabbits with lung injury.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;14(4):738-44.
1999: Vázquez de Anda G F; Hartog A; Verbrugge S J; Gommers D; Lachmann B
The open lung concept: pressure-controlled ventilation is as effective as high-frequency oscillatory ventilation in improving gas exchange and lung mechanics in surfactant-deficient animals.
Intensive care medicine 1999;25(9):990-6.
1999: Verbrugge S J; de Jong J W; Keijzer E; Vazquez de Anda G; Lachmann B
Purine in bronchoalveolar lavage fluid as a marker of ventilation-induced lung injury.
Critical care medicine 1999;27(4):779-83.
1999: Van't Veen A; Gommers D; Verbrugge S J; Wollmer P; Mouton J W; Kooij P P; Lachmann B
Lung clearance of intratracheally instilled 99mTc-tobramycin using pulmonary surfactant as vehicle.
British journal of pharmacology 1999;126(5):1091-6.
1999: Verbrugge S J; Lachmann B
Mechanisms of ventilation-induced lung injury: physiological rationale to prevent it.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo 1999;54(1):22-37.
1999: Hartog A; Vazquez de Anda G F; Gommers D; Kaisers U; Verbrugge S J; Schnabel R; Lachmann B
Comparison of exogenous surfactant therapy, mechanical ventilation with high end-expiratory pressure and partial liquid ventilation in a model of acute lung injury.
British journal of anaesthesia 1999;82(1):81-6.
1999: Tusman G; Böhm S H; Vazquez de Anda G F; do Campo J L; Lachmann B
'Alveolar recruitment strategy' improves arterial oxygenation during general anaesthesia.
British journal of anaesthesia 1999;82(1):8-13.
1998: So K L; de Buijzer E; Gommers D; Kaisers U; van Genderen P J; Lachmann B
Surfactant therapy restores gas exchange in lung injury due to paraquat intoxication in rats.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;12(2):284-7.
1998: Verbrugge S J; Vazquez de Anda G; Gommers D; Neggers S J; Sorm V; Böhm S H; Lachmann B
Exogenous surfactant preserves lung function and reduces alveolar Evans blue dye influx in a rat model of ventilation-induced lung injury.
Anesthesiology 1998;89(2):467-74.
1998: Gommers D; Eijking E P; So K L; van't Veen A; Lachmann B
Bronchoalveolar lavage with a diluted surfactant suspension prior to surfactant instillation improves the effectiveness of surfactant therapy in experimental acute respiratory distress syndrome (ARDS).
Intensive care medicine 1998;24(5):494-500.
1998: Verbrugge S J; Böhm S H; Gommers D; Zimmerman L J; Lachmann B
Surfactant impairment after mechanical ventilation with large alveolar surface area changes and effects of positive end-expiratory pressure.
British journal of anaesthesia 1998;80(3):360-4.
1998: Verbrugge S J; Sorm V; van 't Veen A; Mouton J W; Gommers D; Lachmann B
Lung overinflation without positive end-expiratory pressure promotes bacteremia after experimental Klebsiella pneumoniae inoculation.
Intensive care medicine 1998;24(2):172-7.
1997: Verbrugge S J; Sorm V; Lachmann B
Mechanisms of acute respiratory distress syndrome: role of surfactant changes and mechanical ventilation.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 1997;48(4):537-57.
1997: Gommers D; Hartog A; van 't Veen A; Lachmann B
Improved oxygenation by nitric oxide is enhanced by prior lung reaeration with surfactant, rather than positive end-expiratory pressure, in lung-lavaged rabbits.
Critical care medicine 1997;25(11):1868-73.
1997: van Blankenstein J H; Slager C J; Soei L K; Boersma H; Stijnen T; Schuurbiers J C; Krams R; Lachmann B; Verdouw P D
Cardiac depression after experimental air embolism in pigs: role of addition of a surface-active agent.
Cardiovascular research 1997;34(3):473-82.
1997: Houmes R J; Hartog A; Verbrugge S J; Böhm S; Lachmann B
Combining partial liquid ventilation with nitric oxide to improve gas exchange in acute lung injury.
Intensive care medicine 1997;23(2):163-9.
1997: Huygen P E; Hartog A; Kolle C; Oosterbosch E; Lachmann B
An in-line oxygen gas-fraction sensor for anesthesia and intensive care.
Advances in experimental medicine and biology 1997;428():579-83.
1997: Hartog A; Houmes R J; Verbrugge S J; Erdmann W; Lachmann B
Partial liquid ventilation and inhaled nitric oxide have a cumulative effect in improving arterial oxygenation in experimental ARDS.
Advances in experimental medicine and biology 1997;428():281-3.
1997: Hartog A; Gommers D; van 't Veen A; Erdmann W; Lachmann B
Exogenous surfactant and nitric oxide have a synergistic effect in improving gas exchange in experimental ARDS.
Advances in experimental medicine and biology 1997;428():277-9.
1997: Lachmann B; Rajan N G
New ventilatory strategies in intensive care.
Acta anaesthesiologica Scandinavica. Supplementum 1997;111():69-74.
1996: van't Veen A; Mouton J W; Gommers D; Lachmann B
Pulmonary surfactant as vehicle for intratracheally instilled tobramycin in mice infected with Klebsiella pneumoniae.
British journal of pharmacology 1996;119(6):1145-8.
1996: Verbrugge S J; Gommers D; Bos J A; Hansson C; Wollmer P; Bakker W H; Lachmann B
Pulmonary 99mTc-human serum albumin clearance and effects of surfactant replacement after lung lavage in rabbits.
Critical care medicine 1996;24(9):1518-23.
1996: van 't Veen A; Gommers D; Mouton J W; Kluytmans J A; Krijt E J; Lachmann B
Exogenous pulmonary surfactant as a drug delivering agent: influence of antibiotics on surfactant activity.
British journal of pharmacology 1996;118(3):593-8.
1996: Tütüncü A S; Houmes R J; Bos J A; Wollmer P; Lachmann B
Evaluation of lung function after intratracheal perfluorocarbon administration in healthy animals.
Critical care medicine 1996;24(2):274-9.
1996: Kesecioglu J; Telci L; Tütüncü A S; Esen F; Denkel T; Erdmann W; Akpir K; Lachmann B
Effects of volume controlled ventilation with PEEP, pressure regulated volume controlled ventilation and low frequency positive pressure ventilation with extracorporeal carbon dioxide removal on total static lung compliance and oxygenation in pigs with ARDS.
Advances in experimental medicine and biology 1996;388():629-36.
1996: So K L; Lachmann B
The lung in distress.
Advances in experimental medicine and biology 1996;388():463-71.
1995: Houmes R J; Verbrugge S J; Hendrik E R; Lachmann B
Hemodynamic effects of partial liquid ventilation with perfluorocarbon in acute lung injury.
Intensive care medicine 1995;21(12):966-72.
1995: Hartog A; Gommers D; Lachmann B
Role of surfactant in the pathophysiology of the acute respiratory distress syndrome (ARDS).
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo 1995;50(5):372-7.
1995: van 't Veen A; Mouton J W; Gommers D; Kluytmans J A; Dekkers P; Lachmann B
Influence of pulmonary surfactant on in vitro bactericidal activities of amoxicillin, ceftazidime, and tobramycin.
Antimicrobial agents and chemotherapy 1995;39(2):329-33.
1995: Lachmann B
Xenon anesthesia: prerequisite for its use in a closed circuit system.
Applied cardiopulmonary pathophysiology : ACP 1995;5 Suppl 2():59-61.
1994: Kesecioglu J; Telci L; Esen F; Akpir K; Tütüncü A S; Denkel T; Erdmann W; Lachmann B
Respiratory and haemodynamic effects of conventional volume controlled PEEP ventilation, pressure regulated volume controlled ventilation and low frequency positive pressure ventilation with extracorporeal carbon dioxide removal in pigs with acute ARDS.
Acta anaesthesiologica Scandinavica 1994;38(8):879-84.
1994: Lachmann B; Eijking E P; So K L; Gommers D
In vivo evaluation of the inhibitory capacity of human plasma on exogenous surfactant function.
Intensive care medicine 1994;20(1):6-11.
1994: Kesecioglu J; Denkel T; Esen F; Telci L; Akpir K; Erdmann W; Lachmann B
Effects of different modes of ventilation on oxygenation and intracranial pressure of pigs with surfactant depleted lungs.
Advances in experimental medicine and biology 1994;345():95-100.
1994: van 't Veen A; So K L; Lachmann B
Surfactant replacement therapy in animal models of respiratory failure due to viral infection.
Advances in experimental medicine and biology 1994;345():83-94.
1994: Kesecioglu J; Telci L; Tütüncü A S; Esen F; Erdmann W; Lachmann B
Effects of different mechanical ventilation modes on oxygenation in surfactant depleted rabbit lungs.
Advances in experimental medicine and biology 1994;361():437-42.
1993: Tütüncü A S; Akpir K; Mulder P; Erdmann W; Lachmann B
Intratracheal perfluorocarbon administration as an aid in the ventilatory management of respiratory distress syndrome.
Anesthesiology 1993;79(5):1083-93.
1993: Segerer H; van Gelder W; Angenent F W; van Woerkens L J; Curstedt T; Obladen M; Lachmann B
Pulmonary distribution and efficacy of exogenous surfactant in lung-lavaged rabbits are influenced by the instillation technique.
Pediatric research 1993;34(4):490-4.
1993: Tütüncü A S; Faithfull N S; Lachmann B
Comparison of ventilatory support with intratracheal perfluorocarbon administration and conventional mechanical ventilation in animals with acute respiratory failure.
The American review of respiratory disease 1993;148(3):785-92.
1993: Den Boer M O; Van Woerkens L J; Somers J A; Duncker D J; Lachmann B; Saxena P R; Verdouw P D
On the preservation and regulation of vascular tone in arteriovenous anastomoses during anesthesia.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;75(2):782-9.
1993: Tütüncü A S; Faithfull N S; Lachmann B
Intratracheal perfluorocarbon administration combined with mechanical ventilation in experimental respiratory distress syndrome: dose-dependent improvement of gas exchange.
Critical care medicine 1993;21(7):962-9.
1993: Eijking E P; Gommers D; So K L; Vergeer M; Lachmann B
Surfactant treatment of respiratory failure induced by hydrochloric acid aspiration in rats.
Anesthesiology 1993;78(6):1145-51.
1993: Gommers D; Vilstrup C; Bos J A; Larsson A; Werner O; Hannappel E; Lachmann B
Exogenous surfactant therapy increases static lung compliance, and cannot be assessed by measurements of dynamic compliance alone.
Critical care medicine 1993;21(4):567-74.
1993: Eijking E P; Gommers D; So K L; de Maat M P; Mouton J W; Lachmann B
Prevention of respiratory failure after hydrochloric acid aspiration by intratracheal surfactant instillation in rats.
Anesthesia and analgesia 1993;76(3):472-7.
1993: So K L; Gommers D; Lachmann B
Bronchoalveolar surfactant system and intratracheal adrenaline.
Lancet 1993;341(8837):120-1.
1992: Vilstrup C; Gommers D; Bos J A; Lachmann B; Werner O; Larsson A
Natural surfactant instilled in premature lambs increases lung volume and improves ventilation homogeneity within five minutes.
Pediatric research 1992;32(5):595-9.
1992: Stouten E M; Armbruster S; Houmes R J; Prakash O; Erdmann W; Lachmann B
Comparison of ketorolac and morphine for postoperative pain after major surgery.
Acta anaesthesiologica Scandinavica 1992;36(7):716-21.
1992: Vilstrup C T; Björklund L J; Larsson A; Lachmann B; Werner O
Functional residual capacity and ventilation homogeneity in mechanically ventilated small neonates.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;73(1):276-83.
1992: Bos J A; Wollmer P; Bakker W; Hannappel E; Lachmann B
Clearance of 99mTc-DTPA and experimentally increased alveolar surfactant content.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;72(4):1413-7.
1992: Houmes R J; Voets M A; Verkaaik A; Erdmann W; Lachmann B
Efficacy and safety of tramadol versus morphine for moderate and severe postoperative pain with special regard to respiratory depression.
Anesthesia and analgesia 1992;74(4):510-4.
1992: Van Daal G J; Bos J A; Eijking E P; Gommers D; Hannappel E; Lachmann B
Surfactant replacement therapy improves pulmonary mechanics in end-stage influenza A pneumonia in mice.
The American review of respiratory disease 1992;145(4 Pt 1):859-63.
1992: Houmes R J; Bos J A; Lachmann B
Effect of different ventilator settings on lung mechanics: with special reference to the surfactant system.
Applied cardiopulmonary pathophysiology : ACP 1992;5(2):117-27.
1992: van Daal G J; van 't Veen A; So K L; Mouton J W; Smit F; van Hal P T; Bergmann K C; Lachmann B
Oral immunization with polyvalent bacterial lysate and infection with Streptococcus pneumoniae: influence on interferon-gamma and PMN elastase concentrations in murine bronchoalveolar lavage fluid.
International archives of allergy and immunology 1992;97(2):173-7.
1992: van Daal G J; Eijking E P; So K L; Fievez R B; Sprenger M J; van Dam D W; Erdmann W; Lachmann B
Acute respiratory failure during pneumonia induced by Sendai virus.
Advances in experimental medicine and biology 1992;316():319-26.
1992: Kesecioglu J; Telci L; Esen F; Denkel T; Akpir K; Tütüncü A S; Erdmann W; Lachmann B
Evaluation of oxygenation with different modes of ventilation in patients with adult respiratory distress syndrome.
Advances in experimental medicine and biology 1992;317():901-6.
1992: Kesecioglu J; Telci L; Denkel T; Tütüncü A S; Esen F; Akpir K; Lachmann B
Comparison of different modes of artificial ventilation with extracorporeal CO2 elimination on gas exchange in an animal model of acute respiratory failure.
Advances in experimental medicine and biology 1992;317():893-9.
1992: Telci L; Kesecioglu J; Esen F; Denkel T; Tütüncü A S; Akpir K; Lachmann B
Effects of CPPV, PC-IRV, and LFPPV-ECCO2R on right ventricular functions in pigs with ARDS.
Advances in experimental medicine and biology 1992;317():599-604.
1992: Gommers D; van Daal G J; Lachmann B
Oxygen uptake in the lungs under pathological conditions and its therapeutic efforts.
Advances in experimental medicine and biology 1992;317():47-54.
1992: Lachmann B; Tütüncü A S; Bos J A; Faithfull N S; Erdmann W
Perflubron (perfluorooctylbromide) instillation combined with mechanical ventilation: an alternative treatment of acute respiratory failure in adult animals.
Advances in experimental medicine and biology 1992;317():409-12.
1992: Tütüncü A S; Akpir K; Mulder P; Faithfull N S; Erdmann W; Lachmann B
Gas exchange and lung mechanics during long-term mechanical ventilation with intratracheal perfluorocarbon administration in respiratory distress syndrome.
Advances in experimental medicine and biology 1992;317():401-7.
1992: Tütüncü A S; Lachmann B; Faithfull N S; Erdmann W
Dose-dependent improvement of gas exchange by intratracheal perflubron (perfluorooctylbromide) instillation in adult animals with acute respiratory failure.
Advances in experimental medicine and biology 1992;317():397-400.
1992: Esen F; Denkel T; Telci L; Kesecioglu J; Tütüncü A S; Akpir K; Lachmann B
Comparison of pressure support ventilation (PSV) and intermittent mandatory ventilation (IMV) during weaning in patients with acute respiratory failure.
Advances in experimental medicine and biology 1992;317():371-6.
1992: Tenbrinck R; Sluiter W; Silveri F; Bos A P; Scheffers E C; Go A T; Bos J A; Tibboel D; Lachmann B
Effect of artificial ventilation on pulmonary antioxidant enzyme activities in a congenital diaphragmatic hernia rat model.
Advances in experimental medicine and biology 1992;317():363-70.
1992: Eijking E P; Gommers D; Kullander J; de Buijzer E; Beukenholdt R W; Lachmann B
Different surfactant treatment strategies for respiratory failure induced by hydrochloric acid aspiration in rats.
Advances in experimental medicine and biology 1992;317():349-55.
1992: Eijking E P; Bos J A; Schelter W; Gumbrecht W; Erdmann W; Lachmann B
A new catheter for quasi-continuous measurement of arterial partial oxygen pressure.
Advances in experimental medicine and biology 1992;316():71-4.
1992: Bos J A; Wollmer P; Erdmann W; Lachmann B
99mTc-DTPA clearance: a sensitive method for early detection of an impending disturbance in gas exchange.
Advances in experimental medicine and biology 1992;316():311-7.
1992: Eijking E P; van Daal G J; Tenbrinck R; Sluiters J F; Hannappel E; Erdmann W; Lachmann B
Improvement of pulmonary gas exchange after surfactant replacement in rats with Pneumocystis carinii pneumonia.
Advances in experimental medicine and biology 1992;316():293-8.
1991: Eijking E P; Strayer D S; van Daal G J; Tenbrinck R; Merritt T A; Hannappel E; Lachmann B
In vivo and in vitro inactivation of bovine surfactant by an anti-surfactant monoclonal antibody.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1991;4(10):1245-50.
1991: van Daal G J; So K L; Gommers D; Eijking E P; Fiévez R B; Sprenger M J; van Dam D W; Lachmann B
Intratracheal surfactant administration restores gas exchange in experimental adult respiratory distress syndrome associated with viral pneumonia.
Anesthesia and analgesia 1991;72(5):589-95.
1991: Eijking E P; Strayer D S; van Daal G J; Lachmann B
Effects of antisurfactant antibodies on the course of mild respiratory distress syndrome.
Pathobiology : journal of immunopathology, molecular and cellular biology 1991;59(2):96-101.
1991: van Daal G J; Lachmann B
Induction of a mucosal immune response by oral immunization. An overview.
Zeitschrift für Erkrankungen der Atmungsorgane 1991;177(1-2):20-34.
1991: Eijking E P; van Daal G J; Tenbrinck R; Luijendijk A; Sluiters J F; Hannappel E; Lachmann B
Effect of surfactant replacement on Pneumocystis carinii pneumonia in rats.
Intensive care medicine 1991;17(8):475-8.
1991: Van Daal G J; Beusenberg F D; So K L; Fiévez R B; Sprenger M J; Mouton J W; Van 't Veen A; Lachmann B
Protection against influenza A virus infection in mice by oral immunization with a polyvalent bacterial lysate.
International journal of immunopharmacology 1991;13(7):831-40.
1990: van Daal G J; So K L; Mouton J W; van 't Veen A; Tenbrinck R; Bergmann K C; Lachmann B
Oral immunization with a polyvalent bacterial lysate can reduce mortality by infection with S. pneumoniae or influenza A in mice.
Pneumologie (Stuttgart, Germany) 1990;44(10):1180-2.
1990: Wollmer P; Schairer W; Bos J A; Bakker W; Krenning E P; Lachmann B
Pulmonary clearance of 99mTc-DTPA during halothane anaesthesia.
Acta anaesthesiologica Scandinavica 1990;34(7):572-5.
1990: Lachmann B; Armbruster S; Schairer W; Landstra M; Trouwborst A; Van Daal G J; Kusuma A; Erdmann W
Safety and efficacy of xenon in routine use as an inhalational anaesthetic.
Lancet 1990;335(8703):1413-5.
1990: Boomsma F; Rupreht J; Man in 't Veld A J; de Jong F H; Dzoljic M; Lachmann B
Haemodynamic and neurohumoral effects of xenon anaesthesia. A comparison with nitrous oxide.
Anaesthesia 1990;45(4):273-8.
1990: Lachmann B
Does surfactant play a role in acute respiratory failure?
Middle East journal of anesthesiology 1990;10(4):377-87.
1990: Lachmann B
How to set the ventilator in acute respiratory failure.
Middle East journal of anesthesiology 1990;10(4):367-75.
1990: Eijking E P; Bos J A; Armbruster S; Schelter W; Gumbrecht W; Erdmann W; Lachmann B
Online measurements of SaO2, Ht and Hb using a micro transmission cell.
Advances in experimental medicine and biology 1990;277():53-7.
1990: Bos J A; Schelter W; Gumbrecht W; Montag B; Eijking E P; Armbruster S; Erdmann W; Lachmann B
Development of a micro transmission cell for in vivo measurement of SaO2 and Hb.
Advances in experimental medicine and biology 1990;277():47-52.
1990: van Daal G J; de Jong P T; Tenbrinck R; Mouton J W; Petzoldt K; Bergmann K C; Lachmann B
Oral immunization with bacterial lysate against infection with Streptococcus pneumoniae in mice.
Respiration; international review of thoracic diseases 1990;57(4):229-32.
1989: Lachmann B
Animal models and clinical pilot studies of surfactant replacement in adult respiratory distress syndrome.
The European respiratory journal. Supplement 1989;3():98s-103s.
1989: Lachmann B; Schairer W; Hafner M; Armbruster S; Jonson B
Volume-controlled ventilation with superimposed high frequency ventilation during expiration in healthy and surfactant-depleted pig lungs.
Acta anaesthesiologica Scandinavica. Supplementum 1989;90():117-9.
1989: van Daal G J; Lachmann B; Schairer W; Tenbrinck R; van Woerkens L J; Verdouw P; Erdmann W
The influence of different anesthetics on the oxygen delivery to and consumption of the heart.
Advances in experimental medicine and biology 1989;248():527-32.
1989: Tenbrinck R; Schairer W; van Daal G J; Kuypers M H; Steeghs G F; Lachmann B
Evaluation of a heparin-coated PO2 electrode for continuous intravasal PO2 monitoring.
Advances in experimental medicine and biology 1989;248():157-62.
1989: Lachmann B
Animal studies of surfactant replacement therapy.
Developmental pharmacology and therapeutics 1989;13(2-4):164-72.
1989: Bos J A; Schairer W; Schaffers J T; Tenbrinck R; TenHave-Opbroek A A; Bakker W H; Wollmer P; Lachmann B
Effects of high frequency jet ventilation on the pulmonary clearance of 99mTc-DTPA in respiratory failure in rabbits.
British journal of anaesthesia 1989;63(7 Suppl 1):59S-64S.
1989: van Woerkens L J; Lachmann B; van Daal G J; Schairer W; Tenbrinck R; Verdouw P D; Erdmann W
Influences of different routinely used muscle relaxants on oxygen delivery to and oxygen consumption by the heart during xenon-anesthesia.
Advances in experimental medicine and biology 1989;248():673-8.
1989: Lachmann B
Surfactant therapy.
Resuscitation 1989;18 Suppl():S37-49.
1989: Lachmann B; Schairer W; Armbruster S; van Daal G J; Erdmann W
Improved arterial oxygenation and CO2 elimination following changes from volume-generated PEEP ventilation with inspiratory/expiratory (I/E) ratio of 1:2 to pressure-generated ventilation with I/E ratio of 4:1 in patients with severe adult respiratory distress syndrome (ARDS).
Advances in experimental medicine and biology 1989;248():779-86.
1989: Lachmann B; Schairer W; Armbruster S; van Daal G J; Erdmann W
Effects of different inspiratory/expiratory (I/E) ratios and PEEP-ventilation on blood gases and hemodynamics in dogs with severe respiratory distress syndrome (RDS).
Advances in experimental medicine and biology 1989;248():769-77.
1988: Armbruster S; Lachmann B; Erdmann W
Non-invasive pulse oximetry during lung lavage.
Advances in experimental medicine and biology 1988;222():519-22.
1988: Lachmann B; Armbruster S; Erdmann W
Oxygen uptake and surfactant replacement.
Advances in experimental medicine and biology 1988;222():511-7.
1988: Lachmann B; Jonson B; Erdmann W
Improving cardiocirculatory parameters and oxygen transport capacity by shifting the pH to the alkaline side.
Advances in experimental medicine and biology 1988;222():455-62.
1988: Erdmann W; Chen C F; Armbruster S; Lachmann B
Autoregulation of intracellular PO2 in aplysia giant neurons and response of neuronal activity following changes in extracellular PO2.
Advances in experimental medicine and biology 1988;222():397-402.
1987: Lachmann B; Saugstad O D; Klein J; Erdmann W
Acute respiratory failure induced by tracheal instillation of xanthine oxidase, its prevention and therapy by exogenous surfactant instillation.
Advances in experimental medicine and biology 1987;215():351-4.
1987: Armbruster S; Klein J; Stouten E M; Erdmann W; Lachmann B
Surfactant in pulmonary oxygen toxicity.
Advances in experimental medicine and biology 1987;215():345-9.

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