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John LaFrancois

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Chemicals & Drugs

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Publications

TOP 3
W Haung Yu; Yasuji Matsuoka; István Sziráki; Audrey Hashim; John LaFrancois; Henry Sershen; karen duff
Increased dopaminergic neuron sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in transgenic mice expressing mutant A53T alpha-synuclein.
Adam R Cole; Wendy Noble; Lidy van Aalten; Florian Plattner; Rena Meimaridou; Dale Hogan; Margaret Taylor; John LaFrancois; Frank J Gunn-Moore; Alexei Verkhratsky; Salvatore Oddo; Frank M LaFerla; peter giese; Kelly T Dineley; karen duff; Jill C Richardson; Shi Du Yan; Diane P Hanger; Stuart M Allan; Calum Sutherland
Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer's disease progression.
Audrey J Gray; Gaku Sakaguchi; Chiharu Shiratori; Amanda Becker; John LaFrancois; Paul S Aisen; karen duff; Yasuji Matsuoka
Antibody against C-terminal Abeta selectively elevates plasma Abeta.

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All Publications

2008: W Haung Yu; Yasuji Matsuoka; István Sziráki; Audrey Hashim; John LaFrancois; Henry Sershen; karen duff
Increased dopaminergic neuron sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in transgenic mice expressing mutant A53T alpha-synuclein.
Neurochemical research 2008;33(5):902-11.
2007: Adam R Cole; Wendy Noble; Lidy van Aalten; Florian Plattner; Rena Meimaridou; Dale Hogan; Margaret Taylor; John LaFrancois; Frank J Gunn-Moore; Alexei Verkhratsky; Salvatore Oddo; Frank M LaFerla; peter giese; Kelly T Dineley; karen duff; Jill C Richardson; Shi Du Yan; Diane P Hanger; Stuart M Allan; Calum Sutherland
Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer's disease progression.
Journal of neurochemistry 2007;103(3):1132-44.
2007: Audrey J Gray; Gaku Sakaguchi; Chiharu Shiratori; Amanda Becker; John LaFrancois; Paul S Aisen; karen duff; Yasuji Matsuoka
Antibody against C-terminal Abeta selectively elevates plasma Abeta.
Neuroreport 2007;18(3):293-6.
2005: Wendy Noble; Emmanuel Planel; Cindy Zehr; Vicki Olm; Jordana Meyerson; Farhana Suleman; Kate Gaynor; Lili Wang; John LaFrancois; Boris Feinstein; Mark Burns; Pavan Krishnamurthy; Yi Wen; Ratan Bhat; Jada Lewis; dennis dickson; karen duff
Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(19):6990-5.
2005: Yasuji Matsuoka; Li Shao; Manik Debnath; John LaFrancois; Amanda Becker; Audrey Gray; Paul S Aisen; Chester Mathis; William E Klunk; karen duff
An Abeta sequestration approach using non-antibody Abeta binding agents.
Current Alzheimer research 2005;2(2):265-8.
2003: Cynthia A Lemere; Edward T Spooner; John LaFrancois; Brian Malester; Chica Mori; Jodi F Leverone; Yasuji Matsuoka; Jennie W Taylor; Ronald B DeMattos; David M Holtzman; John Clements; Dennis J Selkoe; karen duff
Evidence for peripheral clearance of cerebral Abeta protein following chronic, active Abeta immunization in PSAPP mice.
Neurobiology of disease 2003;14(1):10-8.
2003: Mark Burns; Kate Gaynor; Vicki Olm; Marc Mercken; John LaFrancois; Lili Wang; Paul Mathews; Wendy Noble; Yasuji Matsuoka; karen duff
Presenilin redistribution associated with aberrant cholesterol transport enhances beta-amyloid production in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(13):5645-9.
2003: Wendy Noble; Vicki Olm; Kazuyuki Takata; Evelyn Casey; O Mary; Jordana Meyerson; Kate Gaynor; John LaFrancois; Lili Wang; Takayuki Kondo; Peter Davies; Mark Burns; Ralph A. Nixon; dennis dickson; Yasuji Matsuoka; Michael K Ahlijanian; Lit-Fui Lau; karen duff
Cdk5 is a key factor in tau aggregation and tangle formation in vivo.
Neuron 2003;38(4):555-65.
2003: Mark Burns; Wendy J Noble; Vicki Olm; Kate Gaynor; Evelyn Casey; John LaFrancois; Lili Wang; karen duff
Co-localization of cholesterol, apolipoprotein E and fibrillar Abeta in amyloid plaques.
Brain research. Molecular brain research 2003;110(1):119-25.
2003: Yasuji Matsuoka; Mitsuo Saito; John LaFrancois; Mariko Saito; Kate Gaynor; Vicki Olm; Lili Wang; Evelyn Casey; Yifan Lu; Chiharu Shiratori; Cynthia A Lemere; karen duff
Novel therapeutic approach for the treatment of Alzheimer's disease by peripheral administration of agents with an affinity to beta-amyloid.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(1):29-33.
2002: Hui Zheng; H Xu; S N Uljon; R Gross; K Hardy; J Gaynor; John LaFrancois; J Simpkins; Lorenzo M Refolo; Suzana Petanceska; Runsheng Wang; karen duff
Modulation of A(beta) peptides by estrogen in mouse models.
Journal of neurochemistry 2002;80(1):191-6.
2001: Lorenzo M Refolo; Miguel Pappolla; John LaFrancois; Brian Malester; Stephen D Schmidt; T Thomas-Bryant; Stephen G Tint; Runsheng Wang; Marc Mercken; Suzana Petanceska; karen duff
A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease.
Neurobiology of disease 2001;8(5):890-9.
2001: Yasuji Matsuoka; Miquel Vila; Sarah J Lincoln; Alison L McCormack; M Picciano; John LaFrancois; X Yu; dennis dickson; William J Langston; E McGowan; Matthew J Farrer; John Hardy; karen duff; Serge Przedborski; Donato A Di Monte
Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter.
Neurobiology of disease 2001;8(3):535-9.
2001: Yasuji Matsuoka; M Picciano; Brian Malester; John LaFrancois; C Zehr; J M Daeschner; John A Olschowka; Maria I Fonseca; M Kerry O'Banion; Andrea J Tenner; Cynthia A Lemere; karen duff
Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease.
The American journal of pathology 2001;158(4):1345-54.
2000: Lorenzo M Refolo; Brian Malester; John LaFrancois; Tara Bryant-Thomas; Runsheng Wang; Stephen G Tint; Kumar Sambamurti; karen duff; Miguel Pappolla
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model.
Neurobiology of disease 2000;7(4):321-31.