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Janne Lähdesmäki

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Umit Kazim Ozdoğan; Janne Lähdesmäki; Mika Scheinin
The analgesic efficacy of partial opioid agonists is increased in mice with targeted inactivation of the alpha2A-adrenoceptor gene.
Umit Kazim Ozdogan; Janne Lähdesmäki; Kristo Hakala; Mika Scheinin
The involvement of alpha 2A-adrenoceptors in morphine analgesia, tolerance and withdrawal in mice.
Heikki Mansikka; Janne Lähdesmäki; Mika Scheinin; Antti Pertovaara
Alpha(2A) adrenoceptors contribute to feedback inhibition of capsaicin-induced hyperalgesia.

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All Publications

2006: Umit Kazim Ozdoğan; Janne Lähdesmäki; Mika Scheinin
The analgesic efficacy of partial opioid agonists is increased in mice with targeted inactivation of the alpha2A-adrenoceptor gene.
European journal of pharmacology 2006;529(1-3):105-13.
2004: Umit Kazim Ozdogan; Janne Lähdesmäki; Kristo Hakala; Mika Scheinin
The involvement of alpha 2A-adrenoceptors in morphine analgesia, tolerance and withdrawal in mice.
European journal of pharmacology 2004;497(2):161-71.
2004: Heikki Mansikka; Janne Lähdesmäki; Mika Scheinin; Antti Pertovaara
Alpha(2A) adrenoceptors contribute to feedback inhibition of capsaicin-induced hyperalgesia.
Anesthesiology 2004;101(1):185-90.
2004: Janne Lähdesmäki; Jukka Sallinen; Ewen MacDonald; Mika Scheinin
Alpha2A-adrenoceptors are important modulators of the effects of D-amphetamine on startle reactivity and brain monoamines.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(7):1282-93.
2004: Umit Kazim Ozdoğan; Janne Lähdesmäki; Heikki Mansikka; Mika Scheinin
Loss of amitriptyline analgesia in alpha 2A-adrenoceptor deficient mice.
European journal of pharmacology 2004;485(1-3):193-6.
2003: Janne Lähdesmäki; Jukka Sallinen; Ewen MacDonald; Jouni Sirviö; Mika Scheinin
Alpha2-adrenergic drug effects on brain monoamines, locomotion, and body temperature are largely abolished in mice lacking the alpha2A-adrenoceptor subtype.
Neuropharmacology 2003;44(7):882-92.
2003: Janne Lähdesmäki; Mika Scheinin; Antti Pertovaara; Heikki Mansikka
The alpha2A-adrenoceptor subtype is not involved in inflammatory hyperalgesia or morphine-induced antinociception.
European journal of pharmacology 2003;468(3):183-9.
2003: Umit Kazim Ozdoğan; Janne Lähdesmäki; Mika Scheinin
Influence of prazosin and clonidine on morphine analgesia, tolerance and withdrawal in mice.
European journal of pharmacology 2003;460(2-3):127-34.
2002: Janne Lähdesmäki; Jukka Sallinen; Ewen MacDonald; BK Kobilka; Veronica Fagerholm; Mika Scheinin
Behavioral and neurochemical characterization of alpha(2A)-adrenergic receptor knockout mice.
Neuroscience 2002;113(2):289-99.
1999: B Sjöholm; Janne Lähdesmäki; K Pyykkö; M Hillilä; Mika Scheinin
Non-adrenergic binding of [3H]atipamezole in rat kidney--regional distribution and comparison to alpha2-adrenoceptors.
British journal of pharmacology 1999;128(6):1215-22.
1999: Jukka Sallinen; Antti Haapalinna; Ewen MacDonald; Timo Viitamaa; Janne Lähdesmäki; Elena Rybnikova; Markku Pelto-Huikko; BK Kobilka; Mika Scheinin
Genetic alteration of the alpha2-adrenoceptor subtype c in mice affects the development of behavioral despair and stress-induced increases in plasma corticosterone levels.
Molecular psychiatry 1999;4(5):443-52.