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Daniel Laheru

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Nilofer S Azad; Michael A Carducci; Arvind Dasari; Luis Alberto Diaz; Ross C Donehower; Manuel Hidalgo; Daniel Laheru; Martine McManus; Kevin Quackenbush; MICHELLE RUDEK-RENAUT; Gretchen E Taylor; John J Wright; Ming Zhao; John Arcaroli; Wells A Messersmith
Phase I pharmacokinetic and pharmacodynamic study of cetuximab, irinotecan and sorafenib in advanced colorectal cancer.
JOSEPH HERMAN; Sarah E Hoffe; Jason Klapman; Hongyan Cai; Marcia Canto; Kenneth J Chang; Ross C Donehower; Timothy M Pawlik; Tony Reid; Alexander Rosemurgy; Dionne T Savage; Raj J Shah; Gretchen E Taylor; Phuoc Tran; Hao Wang; Aaron T Wild; Christopher L Wolfgang; Mark A Ziegler; Daniel Laheru
Randomized phase III multi-institutional study of TNFerade biologic with fluorouracil and radiotherapy for locally advanced pancreatic cancer: final results.
Daniel Laheru; Barbara A Biedrzycki; Elizabeth M Jaffee
Development of a cytokine-modified allogeneic whole cell pancreatic cancer vaccine.

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All Publications

2013: Nilofer S Azad; Michael A Carducci; Arvind Dasari; Luis Alberto Diaz; Ross C Donehower; Manuel Hidalgo; Daniel Laheru; Martine McManus; Kevin Quackenbush; MICHELLE RUDEK-RENAUT; Gretchen E Taylor; John J Wright; Ming Zhao; John Arcaroli; Wells A Messersmith
Phase I pharmacokinetic and pharmacodynamic study of cetuximab, irinotecan and sorafenib in advanced colorectal cancer.
Investigational new drugs 2013;31(2):345-54.
2013: JOSEPH HERMAN; Sarah E Hoffe; Jason Klapman; Hongyan Cai; Marcia Canto; Kenneth J Chang; Ross C Donehower; Timothy M Pawlik; Tony Reid; Alexander Rosemurgy; Dionne T Savage; Raj J Shah; Gretchen E Taylor; Phuoc Tran; Hao Wang; Aaron T Wild; Christopher L Wolfgang; Mark A Ziegler; Daniel Laheru
Randomized phase III multi-institutional study of TNFerade biologic with fluorouracil and radiotherapy for locally advanced pancreatic cancer: final results.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2013;31(7):886-94.
2013: Daniel Laheru; Barbara A Biedrzycki; Elizabeth M Jaffee
Development of a cytokine-modified allogeneic whole cell pancreatic cancer vaccine.
Methods in molecular biology (Clifton, N.J.) 2013;980():175-203.
2012: Daniel Laheru; DUNG LE; Sheila Linden; Florencia McAllister; RAJESH KUMAR NV; MICHELLE RUDEK-RENAUT; Preeti Shah; Dongweon Song; Gretchen Taylor; Ming Zhao; Ross C Donehower; Howard Goldsweig; Antonio Jimeno; Manuel Hidalgo
Integrated preclinical and clinical development of S-trans, trans-Farnesylthiosalicylic Acid (FTS, Salirasib) in pancreatic cancer.
Investigational new drugs 2012;30(6):2391-9.
2012: Glen J Weiss; Lisa Blaydorn; Mitesh J Borad; Marina Ciomei; francesco Fiorentini; Manuel Hidalgo; Jeffrey D Isaacs; Gayle Jameson; Antonio Jimeno; Daniel Laheru; Maria Adele Pacciarini; Ramesh K Ramanathan; Angela Scaburri; Raoul Tibes; Daniel D Von Hoff
Phase I study of the safety, tolerability and pharmacokinetics of PHA-848125AC, a dual tropomyosin receptor kinase A and cyclin-dependent kinase inhibitor, in patients with advanced solid malignancies.
Investigational new drugs 2012;30(6):2334-43.
2012: Shinichi Yachida; Yi Zhong; Jacqueline A Brosnan; JOSEPH HERMAN; Ralph Hruban; Siân Jones; Alison P Klein; Daniel Laheru; Anne M Macgregor-Das; Richard A Morgan; Yoshiki Naito; Tyler Saunders; Victor E Velculescu; Catherine M White; Christopher L Wolfgang; Christine A Iacobuzio-Donahue
Clinical significance of the genetic landscape of pancreatic cancer and implications for identification of potential long-term survivors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(22):6339-47.
2012: Hari Nathan; Richard D Schulick; Christopher L Wolfgang; John F P Bridges; Michael A Choti; David Peter Cosgrove; Luis Alberto Diaz; BARISH EDIL; JOSEPH HERMAN; Daniel Laheru; Timothy M Pawlik
Treating patients with colon cancer liver metastasis: a nationwide analysis of therapeutic decision making.
Annals of surgical oncology 2012;19(12):3668-76.
2012: Ani Balmanoukian; JOSEPH HERMAN; Daniel Laheru; Xiaobu Ye; Stuart A Grossman
The association between treatment-related lymphopenia and survival in newly diagnosed patients with resected adenocarcinoma of the pancreas.
Cancer investigation 2012;30(8):571-6.
2012: Haoming Qiu; Richard D Schulick; ERIK TRYGGESTAD; Richard Tuli; Hao Wang; Aaron T Wild; Christopher L Wolfgang; John L Cameron; BARISH EDIL; elliot fishman; Amy Hacker-Prietz; Ralph Hruban; Rachit Kumar; Daniel Laheru; Timothy M Pawlik; JOSEPH HERMAN
Comparison of conventional and 3-dimensional computed tomography against histopathologic examination in determining pancreatic adenocarcinoma tumor size: implications for radiation therapy planning.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2012;104(2):167-72.
2012: Susannah Yovino; Richard D Schulick; Christopher L Wolfgang; Richard B Alexander; Olga Goloubeva; Nadar N Hanna; JOSEPH HERMAN; Daniel Laheru; Bert W Maidment; Naimish B Pandya; William F Regine
Analysis of local control in patients receiving IMRT for resected pancreatic cancers.
International journal of radiation oncology, biology, physics 2012;83(3):916-20.
2012: Charles C Hsu; Daniel Laheru; Amol K Narang; Timothy M Pawlik; Raymond Robinson; Richard D Schulick; Michael J Swartz; Jordan M Winter; Christopher L Wolfgang; John L Cameron; Michael A Choti; BARISH EDIL; Ralph Hruban; JOSEPH HERMAN
Early mortality risk score: identification of poor outcomes following upfront surgery for resectable pancreatic cancer.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2012;16(4):753-61.
2012: Shinichi Yachida; Yi Zhong; Roeland F de Wilde; Angelo M DeMarzo; BARISH EDIL; Jessica Hicks; Ralph Hruban; David S Klimstra; Daniel Laheru; Anirban Maitra; Richard Morgan; Tyler Saunders; Richard D Schulick; Rajni Sharma; Chanjuan Shi; Laura H Tang; Efsevia Vakiani; Catherine M White; Christopher L Wolfgang; Christine A Iacobuzio-Donahue
Small cell and large cell neuroendocrine carcinomas of the pancreas are genetically similar and distinct from well-differentiated pancreatic neuroendocrine tumors.
The American journal of surgical pathology 2012;36(2):173-84.
2012: DUNG LE; Jordana Levine; Jana-Lynn Louis; Eric Lutz; Shruti Mathur; Bentley Moyer; Aimee Luck Murphy; John Nemunaitis; Ran Nir-Paz; Alice Pons; Daniel H Sterman; Elizabeth Sugar; Dirk G Brockstedt; Andrea L Cox; Thomas W Dubensky; Joseph E Eiden; Martin Giedlin; Johannes Hampl; Raffit Hassan; PETER ILLEI; Elizabeth M Jaffee; Daniel Laheru
A live-attenuated Listeria vaccine (ANZ-100) and a live-attenuated Listeria vaccine expressing mesothelin (CRS-207) for advanced cancers: phase I studies of safety and immune induction.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(3):858-68.
2012: Ana De Jesus-Acosta; Amanda Blackford; Ki Chung; David Peter Cosgrove; Ross C Donehower; Edna I Flores; Katharine Kinsman; Daniel Laheru; DUNG LE; George R Oliver; Lalan S Wilfong; Lei Zheng; Luis Alberto Diaz
A multicenter analysis of GTX chemotherapy in patients with locally advanced and metastatic pancreatic adenocarcinoma.
Cancer chemotherapy and pharmacology 2012;69(2):415-24.
2012: Sonal Gupta; Seung-Mo Hong; Radha Mukherjee; Roeland F de Wilde; Ana De Jesus-Acosta; Daniel Laheru; Sathyanarayanan Elumalai; Michael Goggins; Dipankar Pramanik; Nathaniel R Campbell; Anirban Maitra
Molecular determinants of retinoic acid sensitivity in pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(1):280-9.
2011: Daniel D Von Hoff; Tina E Wood; Hui Zhang; Mitesh J Borad; Neil Desai; Jose L Iglesias; Ronald L Korn; Daniel Laheru; Anirban Maitra; N V Rajeshkumar; Ramesh K Ramanathan; Tao Shi; Lon S Smith; Patrick Soon-Shiong; Vuong Trieu; Manuel Hidalgo
Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a phase I/II trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(34):4548-54.
2011: Colin D Weekes; Sharyn D Baker; Ross C Donehower; Manuel Hidalgo; Antonio Jimeno; Daniel Laheru; KATHLEEN MURPHY; Sujatha Nallapareddy; Alexis Norris-Kirby; MICHELLE RUDEK-RENAUT; Wells A Messersmith
Thymidylate synthase (TYMS) enhancer region genotype-directed phase II trial of oral capecitabine for 2nd line treatment of advanced pancreatic cancer.
Investigational new drugs 2011;29(5):1057-65.
2011: Ignacio Garrido-Laguna; Elizabeth de Oliveira; Ralph Hruban; Antonio Jimeno; Collins A Karikari; Daniel Laheru; Anirban Maitra; RAJESH KUMAR NV; Belen Rubio-Viqueira; Ana Salomon; Rajni Sharma; Aik Choon Tan; Gretchen Taylor; Maria Uson; Maria C Villaroel; Manuel Hidalgo
Tumor engraftment in nude mice and enrichment in stroma- related gene pathways predict poor survival and resistance to gemcitabine in patients with pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(17):5793-800.
2011: George J Arnaoutakis; John L Cameron; BARISH EDIL; JOSEPH HERMAN; Ralph Hruban; Christine A Iacobuzio-Donahue; Daniel Laheru; Avedis Meneshian; Timothy M Pawlik; Deepa Rangachari; Richard D Schulick; Stephen C Yang; Christopher L Wolfgang
Pulmonary resection for isolated pancreatic adenocarcinoma metastasis: an analysis of outcomes and survival.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2011;15(9):1611-7.
2011: Shinichi Yachida; Yi Zhong; Daniel Laheru; Laura A Morsberger; Raul Patrascu; Meghan B Davis; Constance A Griffin; Ralph Hruban; Christine A Iacobuzio-Donahue
Establishment and characterization of a new cell line, A99, from a primary small cell carcinoma of the pancreas.
Pancreas 2011;40(6):905-10.
2011: Eric Lutz; Charles J Yeo; Keith D Lillemoe; Barbara A Biedrzycki; BARRY KOBRIN; JOSEPH HERMAN; Elizabeth Sugar; Steven Piantadosi; John L Cameron; Sara Solt; Beth Onners; Irena Tartakovsky; Miri Choi; Rajni Sharma; PETER ILLEI; Ralph Hruban; Ross A Abrams; DUNG LE; Elizabeth M Jaffee; Daniel Laheru
A lethally irradiated allogeneic granulocyte-macrophage colony stimulating factor-secreting tumor vaccine for pancreatic adenocarcinoma. A Phase II trial of safety, efficacy, and immune activation.
Annals of surgery 2011;253(2):328-35.
2011: Amol K Narang; Timothy M Pawlik; Richard D Schulick; Jordan M Winter; Christopher L Wolfgang; Jessica Zhou; Sumita Bhatia; John L Cameron; John H Donohue; Michael G Haddock; Ralph Hruban; Charles C Hsu; Daniel Laheru; Robert C Miller; JOSEPH HERMAN
Evaluation of adjuvant chemoradiation therapy for ampullary adenocarcinoma: the Johns Hopkins Hospital-Mayo Clinic collaborative study.
Radiation oncology (London, England) 2011;6():126.
2011: Lei Zheng; Kelly Foley; LANQING HUANG; Ashley Leubner; Guanglan Mo; Kelly Olino; BARISH EDIL; Masamichi Mizuma; Rajni Sharma; DUNG LE; Robert A Anders; PETER ILLEI; Jennifer E Van Eyk; Anirban Maitra; Daniel Laheru; Elizabeth M Jaffee
Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.
PloS one 2011;6(4):e19390.
2011: Jordan M Winter; Amol K Narang; Aaron S Mansfield; JOSEPH HERMAN; John L Cameron; Daniel Laheru; Frederic E Eckhauser; Mathew T Olson; Ralph Hruban; Robert C Miller; Dana Andersen
Resectable pancreatic small cell carcinoma.
Rare tumors 2011;3(1):e5.
2011: Maria C Villarroel; N V Rajeshkumar; Ignacio Garrido-Laguna; Ana De Jesus-Acosta; Siân Jones; Anirban Maitra; Ralph Hruban; James R Eshleman; Alison P Klein; Daniel Laheru; Ross C Donehower; Manuel Hidalgo
Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer.
Molecular cancer therapeutics 2011;10(1):3-8.
2010: Raffit Hassan; Steven J Cohen; Martin Phillips; Ira Pastan; Elad Sharon; Ronan J Kelly; Charles Schweizer; Susan Weil; Daniel Laheru
Phase I clinical trial of the chimeric anti-mesothelin monoclonal antibody MORAb-009 in patients with mesothelin-expressing cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(24):6132-8.
2010: Wells A Messersmith; Antonio Jimeno; Heather A Jacene; Ming Zhao; Piotr Kulesza; Daniel Laheru; Yasmin Kahn; Alexander Spira; Janet Dancey; Christine A Iacobuzio-Donahue; Ross C Donehower; Michael A Carducci; MICHELLE RUDEK-RENAUT; Manuel Hidalgo
Phase I trial of oxaliplatin, infusional 5-fluorouracil, and leucovorin (FOLFOX4) with erlotinib and bevacizumab in colorectal cancer.
Clinical colorectal cancer 2010;9(5):297-304.
2010: Kristin J Redmond; Christopher L Wolfgang; Elizabeth Sugar; Julia Ahn; Hari Nathan; Daniel Laheru; BARISH EDIL; Michael A Choti; Timothy M Pawlik; Ralph Hruban; John L Cameron; JOSEPH HERMAN
Adjuvant chemoradiation therapy for adenocarcinoma of the distal pancreas.
Annals of surgical oncology 2010;17(12):3112-9.
2010: I Garrido-Laguna; Aik Choon Tan; M Uson; M Angenendt; Wen W Ma; M C Villaroel; Ming Zhao; RAJESH KUMAR NV; Antonio Jimeno; Ross C Donehower; Christine A Iacobuzio-Donahue; M Barrett; MICHELLE RUDEK-RENAUT; Belen Rubio-Viqueira; Daniel Laheru; Manuel Hidalgo
Integrated preclinical and clinical development of mTOR inhibitors in pancreatic cancer.
British journal of cancer 2010;103(5):649-55.
2010: Charles C Hsu; JOSEPH HERMAN; Michele M Corsini; Jordan M Winter; Matthew D Callister; Michael G Haddock; John L Cameron; Timothy M Pawlik; Richard D Schulick; Christopher L Wolfgang; Daniel Laheru; Michael B Farnell; Michael J Swartz; Leonard L Gunderson; Robert C Miller
Adjuvant chemoradiation for pancreatic adenocarcinoma: the Johns Hopkins Hospital-Mayo Clinic collaborative study.
Annals of surgical oncology 2010;17(4):981-90.
2010: Zeshaan A Rasheed; Jie Yang; Qiuju Wang; Jeanne Kowalski; Irwin Freed; Christopher Murter; Seung-Mo Hong; Jan-Bart Koorstra; RAJESH KUMAR NV; Xiaobing He; Michael Goggins; Christine A Iacobuzio-Donahue; berman david; Daniel Laheru; Antonio Jimeno; Manuel Hidalgo; Anirban Maitra; William Matsui
Prognostic significance of tumorigenic cells with mesenchymal features in pancreatic adenocarcinoma.
Journal of the National Cancer Institute 2010;102(5):340-51.
2010: Michael J Swartz; Charles C Hsu; Timothy M Pawlik; Jordan Winter; Ralph Hruban; Mehmet Guler; Richard D Schulick; John L Cameron; Daniel Laheru; Christopher L Wolfgang; JOSEPH HERMAN
Adjuvant chemoradiotherapy after pancreatic resection for invasive carcinoma associated with intraductal papillary mucinous neoplasm of the pancreas.
International journal of radiation oncology, biology, physics 2010;76(3):839-44.
2010: Wen Wee Ma; JOSEPH HERMAN; Antonio Jimeno; Daniel Laheru; Wells A Messersmith; Christopher L Wolfgang; John L Cameron; Timothy M Pawlik; Ross C Donehower; MICHELLE RUDEK-RENAUT; Manuel Hidalgo
A tolerability and pharmacokinetic study of adjuvant erlotinib and capecitabine with concurrent radiation in resected pancreatic cancer.
Translational oncology 2010;3(6):373-9.
2010: K Ranh Voong; Jon Davison; Timothy M Pawlik; Manuel O Uy; Charles C Hsu; Jordan Winter; Ralph Hruban; Daniel Laheru; Sonali Rudra; Michael J Swartz; Hari Nathan; BARISH EDIL; Richard D Schulick; John L Cameron; Christopher L Wolfgang; JOSEPH HERMAN
Resected pancreatic adenosquamous carcinoma: clinicopathologic review and evaluation of adjuvant chemotherapy and radiation in 38 patients.
Human pathology 2010;41(1):113-22.
2009: Li Wang; Kieran A Brune; Kala Visvanathan; Daniel Laheru; JOSEPH HERMAN; Christopher L Wolfgang; Richard D Schulick; John L Cameron; Michael Goggins; Ralph Hruban; Alison P Klein
Elevated cancer mortality in the relatives of patients with pancreatic cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(11):2829-34.
2009: Jessica Zhou; Charles C Hsu; Jordan M Winter; Timothy M Pawlik; Daniel Laheru; Michael A Hughes; Ross C Donehower; Christopher L Wolfgang; Umer Akbar; Richard D Schulick; John L Cameron; JOSEPH HERMAN
Adjuvant chemoradiation versus surgery alone for adenocarcinoma of the ampulla of Vater.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009;92(2):244-8.
2009: Amanda Blackford; Oscar K Serrano; Christopher L Wolfgang; Giovanni Parmigiani; Siân Jones; Xiaosong Zhang; DONALD PARSONS; Jimmy Cheng-Ho Lin; Rebecca J Leary; James R Eshleman; Michael Goggins; Elizabeth M Jaffee; Christine A Iacobuzio-Donahue; Anirban Maitra; John L Cameron; Kelly Olino; Richard D Schulick; Jordan Winter; JOSEPH HERMAN; Daniel Laheru; Alison P Klein; Bert Vogelstein; Kenneth W Kinzler; Victor E Velculescu; Ralph Hruban
SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(14):4674-9.
2009: Wen Wee Ma; Heather A Jacene; Dongweon Song; Felip Vilardell; Wells A Messersmith; Daniel Laheru; Richard L Wahl; Christopher J Endres; Antonio Jimeno; Martin G Pomper; Manuel Hidalgo
[18F]fluorodeoxyglucose positron emission tomography correlates with Akt pathway activity but is not predictive of clinical outcome during mTOR inhibitor therapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(16):2697-704.
2009: Christine A Iacobuzio-Donahue; BAOJIN FU; Shinichi Yachida; Mingde Luo; Hisashi Abe; Clark M Henderson; Felip Vilardell; Zheng Wang; Jesse W Keller; Priya Banerjee; JOSEPH HERMAN; John L Cameron; Charles J Yeo; Marc K Halushka; James R Eshleman; Marian Raben; Alison P Klein; Ralph Hruban; Manuel Hidalgo; Daniel Laheru
DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(11):1806-13.
2009: Al B Benson; Thomas A Abrams; Edgar Ben-Josef; P Mark Bloomston; Jean F Botha; Bryan M Clary; Anne Covey; Steven A Curley; Michael D'Angelica; Rene Davila; William D Ensminger; John F Gibbs; Daniel Laheru; Mokenge P Malafa; Jorge A Marrero; Steven G Meranze; Sean J Mulvihill; James Park; James A Posey; Jasgit Sachdev; Riad Salem; Elin R Sigurdson; Constantinos T Sofocleous; Jean-Nicolas Vauthey; Alan P Venook; Laura Williams Goff; Yun Yen; Andrew X Zhu
NCCN clinical practice guidelines in oncology: hepatobiliary cancers.
Journal of the National Comprehensive Cancer Network : JNCCN 2009;7(4):350-91.
2008: Antonio Jimeno; Jing Li; Wells A Messersmith; Daniel Laheru; MICHELLE RUDEK-RENAUT; Manoj Maniar; Manuel Hidalgo; Sharyn D Baker; Ross C Donehower
Phase I study of ON 01910.Na, a novel modulator of the Polo-like kinase 1 pathway, in adult patients with solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(34):5504-10.
2008: Wells A Messersmith; Antonio Jimeno; David S Ettinger; Daniel Laheru; Julie R Brahmer; Dina Lansey; Yasmin Khan; Ross C Donehower; Yusri Elsayed; Peter Zannikos; Manuel Hidalgo
Phase I trial of weekly trabectedin (ET-743) and gemcitabine in patients with advanced solid tumors.
Cancer chemotherapy and pharmacology 2008;63(1):181-8.
2008: Daniel Laheru; Gary Croghan; Ronald Bukowski; MICHELLE RUDEK-RENAUT; Wells A Messersmith; Charles Erlichman; Robert Pelley; Antonio Jimeno; Ross C Donehower; Joseph Boni; Richat Abbas; Patricia Martins; Charles Zacharchuk; Manuel Hidalgo
A phase I study of EKB-569 in combination with capecitabine in patients with advanced colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(17):5602-9.
2008: Antonio Jimeno; MICHELLE RUDEK-RENAUT; Peter Kulesza; Wen W Ma; Jenna Wheelhouse; Anna Howard; Yasmin Khan; Ming Zhao; Heather A Jacene; Wells A Messersmith; Daniel Laheru; Ross C Donehower; Elizabeth Garrett-Mayer; Sharyn D Baker; Manuel Hidalgo
Pharmacodynamic-guided modified continuous reassessment method-based, dose-finding study of rapamycin in adult patients with solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(25):4172-9.
2008: Timothy M Pawlik; Daniel Laheru; Ralph Hruban; Joann Coleman; Christopher L Wolfgang; Kurt Campbell; Syed Z Ali; elliot fishman; Richard D Schulick; JOSEPH HERMAN
Evaluating the impact of a single-day multidisciplinary clinic on the management of pancreatic cancer.
Annals of surgical oncology 2008;15(8):2081-8.
2008: Steven Attia; Jill M Kolesar; Michelle R Mahoney; Henry C Pitot; Daniel Laheru; James Heun; Wei Huang; Jens Eickhoff; Charles Erlichman; Kyle D Holen
A phase 2 consortium (P2C) trial of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) for advanced adenocarcinoma of the pancreas.
Investigational new drugs 2008;26(4):369-79.
2008: JOSEPH HERMAN; Michael J Swartz; Charles C Hsu; Jordan Winter; Timothy M Pawlik; Elizabeth Sugar; Ray Robinson; Daniel Laheru; Elizabeth M Jaffee; Ralph Hruban; Kurtis A Campbell; Christopher L Wolfgang; Fariba Asrari; Ross C Donehower; Manuel Hidalgo; Luis Alberto Diaz; Charles Yeo; John L Cameron; Richard D Schulick; Ross Abrams
Analysis of fluorouracil-based adjuvant chemotherapy and radiation after pancreaticoduodenectomy for ductal adenocarcinoma of the pancreas: results of a large, prospectively collected database at the Johns Hopkins Hospital.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(21):3503-10.
2008: Ralph Hruban; Anirban Maitra; Richard D Schulick; Daniel Laheru; JOSEPH HERMAN; Scott E Kern; Michael Goggins
Emerging molecular biology of pancreatic cancer.
Gastrointestinal cancer research : GCR 2008;2(4 Suppl):S10-5.
2008: Ming Zhao; Ping He; Linping Xu; Manuel Hidalgo; Daniel Laheru; MICHELLE RUDEK-RENAUT
Determination of salirasib (S-trans,trans-farnesylthiosalicylic acid) in human plasma using liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;869(1-2):142-5.
2008: Daniel Laheru; Eric Lutz; James Burke; Barbara A Biedrzycki; Sara Solt; Beth Onners; Irena Tartakovsky; John Nemunaitis; DUNG LE; Elizabeth Sugar; Kristen Hege; Elizabeth M Jaffee
Allogeneic granulocyte macrophage colony-stimulating factor-secreting tumor immunotherapy alone or in sequence with cyclophosphamide for metastatic pancreatic cancer: a pilot study of safety, feasibility, and immune activation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(5):1455-63.
2008: Antonio Jimeno; MICHELLE RUDEK-RENAUT; W. PURCELL; Daniel Laheru; Wells A Messersmith; Janet Dancey; Michael A Carducci; Sharyn D Baker; Manuel Hidalgo; Ross C Donehower
Phase I and pharmacokinetic study of UCN-01 in combination with irinotecan in patients with solid tumors.
Cancer chemotherapy and pharmacology 2008;61(3):423-33.
2008: Antonio Jimeno; Wells A Messersmith; Carlton K K Lee; Wen W Ma; Daniel Laheru; Ross C Donehower; Sharyn D Baker; Manuel Hidalgo
Phase I study of troxacitabine administered by continuous infusion in subjects with advanced solid malignancies.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19(2):374-9.
2008: Domenico Campagna; Leslie Cope; Sindhu S Lakkur; Clark Henderson; Daniel Laheru; Christine A Iacobuzio-Donahue
Gene expression profiles associated with advanced pancreatic cancer.
International journal of clinical and experimental pathology 2008;1(1):32-43.
2007: Michael A Hughes; Deborah A Frassica; Charles J Yeo; Taylor S Riall; Keith D Lillemoe; John L Cameron; Ross C Donehower; Daniel Laheru; Ralph Hruban; Ross A. Abrams
Adjuvant concurrent chemoradiation for adenocarcinoma of the distal common bile duct.
International journal of radiation oncology, biology, physics 2007;68(1):178-82.
2007: Michael J Swartz; Michael A Hughes; Deborah A Frassica; JOSEPH HERMAN; Charles J Yeo; Taylor S Riall; Keith D Lillemoe; John L Cameron; Ross C Donehower; Daniel Laheru; Ralph Hruban; Ross A. Abrams
Adjuvant concurrent chemoradiation for node-positive adenocarcinoma of the duodenum.
Archives of surgery (Chicago, Ill. : 1960) 2007;142(3):285-8.
2006: Al B Benson; Tanios Bekaii-Saab; Edgar Ben-Josef; Leslie H Blumgart; Bryan M Clary; Steven A Curley; Rene Davila; Craig C Earle; William D Ensminger; John F Gibbs; Daniel Laheru; Alan N Langnas; Sean J Mulvihill; Albert A Nemcek; James A Posey; Elin R Sigurdson; Mika Sinanan; Jean-Nicolas Vauthey; Alan P Venook; Lawrence D Wagman; Timothy J Yeatman
Hepatobiliary cancers. Clinical practice guidelines in oncology.
Journal of the National Comprehensive Cancer Network : JNCCN 2006;4(8):728-50.
2006: Valeria Sebastiani; Francesca Ricci; Belen Rubio-Viqueira; Belen Rubio-Viquiera; Piotr Kulesza; Charles J Yeo; Manuel Hidalgo; Alison P Klein; Daniel Laheru; Christine A Iacobuzio-Donahue
Immunohistochemical and genetic evaluation of deoxycytidine kinase in pancreatic cancer: relationship to molecular mechanisms of gemcitabine resistance and survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(8):2492-7.
2005: Lindsey Harle; Todd T Brown; Daniel Laheru; Adrian S Dobs
Omega-3 fatty acids for the treatment of cancer cachexia: issues in designing clinical trials of dietary supplements.
Journal of alternative and complementary medicine (New York, N.Y.) 2005;11(6):1039-46.
2005: Taylor S Riall; John L Cameron; Keith D Lillemoe; Kurtis A Campbell; Patricia K Sauter; JoAnn Coleman; Ross A. Abrams; Daniel Laheru; Ralph Hruban; Charles J Yeo
Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma--part 3: update on 5-year survival.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2005;9(9):1191-204; discussion 1204-6.
2005: Daniel Laheru; Drew M Pardoll; Elizabeth M Jaffee
Genes to vaccines for immunotherapy: how the molecular biology revolution has influenced cancer immunology.
Molecular cancer therapeutics 2005;4(11):1645-52.
2005: Ralph Hruban; Marcia Canto; Constance A Griffin; Scott E Kern; Alison P Klein; Daniel Laheru; Charles J Yeo
Treatment of familial pancreatic cancer and its precursors.
Current treatment options in gastroenterology 2005;8(5):365-75.
2005: Daniel Laheru; Elizabeth M Jaffee
Immunotherapy for pancreatic cancer - science driving clinical progress.
Nature reviews. Cancer 2005;5(6):459-67.
2005: Erlinda E Embuscado; Daniel Laheru; Francesca Ricci; Ki Jung Yun; Sten de Boom Witzel; Allison Seigel; Katie Flickinger; Manuel Hidalgo; G Steven Bova; Christine A Iacobuzio-Donahue
Immortalizing the complexity of cancer metastasis: genetic features of lethal metastatic pancreatic cancer obtained from rapid autopsy.
Cancer biology & therapy 2005;4(5):548-54.
2005: Daniel Laheru; Charles J Yeo
Role of adjuvant therapy in the management of pancreatic cancer.
Advances in surgery 2005;39():223-44.
2005: Daniel Laheru; Barbara A Biedrzycki; Amy M Thomas; Elizabeth M Jaffee
Development of a cytokine-modified allogeneic whole cell pancreatic cancer vaccine.
Methods in molecular medicine 2005;103():299-327.
2004: Wells A Messersmith; Daniel Laheru; Neil Senzer; Ross C Donehower; Paula Grouleff; Theresa Rogers; Sean K Kelley; David A Ramies; Bert L Lum; Manuel Hidalgo
Phase I trial of irinotecan, infusional 5-fluorouracil, and leucovorin (FOLFIRI) with erlotinib (OSI-774): early termination due to increased toxicities.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(19):6522-7.
2004: Amy Morck Thomas; Lynn M Santarsiero; Eric R Lutz; TD Armstrong; Yi-Cheng Chen; LANQING HUANG; Daniel Laheru; Michael Goggins; Ralph Hruban; Elizabeth M Jaffee
Mesothelin-specific CD8(+) T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patients.
The Journal of experimental medicine 2004;200(3):297-306.
2003: Wells A Messersmith; Daniel Laheru; Manuel Hidalgo
Recent advances in the pharmacological treatment of colorectal cancer.
Expert opinion on investigational drugs 2003;12(3):423-34.
2002: Theresa Pluth Yeo; Ralph Hruban; Steven D Leach; Robb E Wilentz; Taylor A Sohn; Scott E Kern; Christine A Iacobuzio-Donahue; Anirban Maitra; Michael Goggins; Marcia Canto; Ross A. Abrams; Daniel Laheru; Elizabeth M Jaffee; Manuel Hidalgo; Charles J Yeo
Pancreatic cancer.
Current problems in cancer 2002;26(4):176-275.
2001: Daniel Laheru; Barbara A Biedrzycki; Elizabeth M Jaffee
Immunologic approaches to the management of pancreatic cancer.
Cancer journal (Sudbury, Mass.) 2001;7(4):324-37.
2001: Elizabeth M Jaffee; Ralph Hruban; Barbara A Biedrzycki; Daniel Laheru; K Schepers; P R Sauter; M Goemann; JoAnn Coleman; Louise B. Grochow; Ross C Donehower; Keith D Lillemoe; Seamus O'Reilly; Ross A. Abrams; Drew M Pardoll; John L Cameron; Charles J Yeo
Novel allogeneic granulocyte-macrophage colony-stimulating factor-secreting tumor vaccine for pancreatic cancer: a phase I trial of safety and immune activation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(1):145-56.
2000: Daniel Laheru; Elizabeth M Jaffee
Potential role of tumor vaccines in GI malignancies.
Oncology (Williston Park, N.Y.) 2000;14(2):245-56; discussion 259-60, 265.
1993: R E Breitbart; C S Liang; L B Smoot; Daniel Laheru; V Mahdavi; B Nadal-Ginard
A fourth human MEF2 transcription factor, hMEF2D, is an early marker of the myogenic lineage.
Development (Cambridge, England) 1993;118(4):1095-106.
1993: David P Goldenberg; L S Bekeart; Daniel Laheru; J D Zhou
Probing the determinants of disulfide stability in native pancreatic trypsin inhibitor.
Biochemistry 1993;32(11):2835-44.
1992: David P Goldenberg; J M Berger; Daniel Laheru; S Wooden; J X Zhang
Genetic dissection of pancreatic trypsin inhibitor.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(11):5083-7.