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Sajani Lakka

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Disorders

Chemicals & Drugs

Living Beings

Anatomy

Physiology

Procedures

Xenograft Model Antitumor Assays

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Co-Publications
Name
44
Rao, Jasti
22
Gujrati, Meena
21
Dinh, Dzung
20
Olivero, William
17
Gondi, Christopher
14
Mohanam, Sanjeeva
9
Kyritsis, Athanassios
9
Yanamandra, Niranjan
8
Chetty, Chandramu
8
Chandrasekar, Nirmala
7
Kin, Yoshiaki
6
Kunigal, Sateesh
6
Jasti, Sushma
6
Bhoopathi, Praveen
5
Ali-Osman, Francis

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Publications

TOP 3
Kunigal Sateesh; Lakka Sajani S; Sodadasu Prasanna Kumar; Estes Norman; Rao Jasti S
Stat3-siRNA induces Fas-mediated apoptosis in vitro and in vivo in breast cancer.
Chetty Chandramu; Bhoopathi Praveen; Rao Jasti S; Lakka Sajani S
Inhibition of matrix metalloproteinase-2 enhances radiosensitivity by abrogating radiation-induced FoxM1-mediated G2/M arrest in A549 lung cancer cells.
Lakka Sajani S; Rao Jasti S
Antiangiogenic therapy in brain tumors.

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All Publications

2009: Kunigal Sateesh; Lakka Sajani S; Sodadasu Prasanna Kumar; Estes Norman; Rao Jasti S
Stat3-siRNA induces Fas-mediated apoptosis in vitro and in vivo in breast cancer.
International journal of oncology 2009;34(5):1209-20.
2009: Chetty Chandramu; Bhoopathi Praveen; Rao Jasti S; Lakka Sajani S
Inhibition of matrix metalloproteinase-2 enhances radiosensitivity by abrogating radiation-induced FoxM1-mediated G2/M arrest in A549 lung cancer cells.
International journal of cancer. Journal international du cancer 2009;124(10):2468-77.
2008: Lakka Sajani S; Rao Jasti S
Antiangiogenic therapy in brain tumors.
Expert review of neurotherapeutics 2008;8(10):1457-73.
2008: Chetty Chandramu; Lakka Sajani S; Bhoopathi Praveen; Kunigal Sateesh; Geiss Roger; Rao Jasti S
Tissue inhibitor of metalloproteinase 3 suppresses tumor angiogenesis in matrix metalloproteinase 2-down-regulated lung cancer.
Cancer research 2008;68(12):4736-45.
2008: Kunigal Sateesh; Lakka Sajani S; Joseph Pushpa; Estes Norman; Rao Jasti S
Matrix metalloproteinase-9 inhibition down-regulates radiation-induced nuclear factor-kappa B activity leading to apoptosis in breast tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(11):3617-26.
2008: Tsung Andrew J; Kargiotis Odysseas; Chetty Chandramu; Lakka Sajani S; Gujrati Meena; Spomar Daniel G; Dinh Dzung H; Rao Jasti S
Downregulation of matrix metalloproteinase-2 (MMP-2) utilizing adenovirus-mediated transfer of small interfering RNA (siRNA) in a novel spinal metastatic melanoma model.
International journal of oncology 2008;32(3):557-64.
2008: Bhoopathi Praveen; Chetty Chandramu; Kunigal Sateesh; Vanamala Sravan K; Rao Jasti S; Lakka Sajani S
Blockade of tumor growth due to matrix metalloproteinase-9 inhibition is mediated by sequential activation of beta1-integrin, ERK, and NF-kappaB.
The Journal of biological chemistry 2008;283(3):1545-52.
2007: Chetty C; Bhoopathi P; Lakka S S; Rao J S
MMP-2 siRNA induced Fas/CD95-mediated extrinsic II apoptotic pathway in the A549 lung adenocarcinoma cell line.
Oncogene 2007;26(55):7675-83.
2007: Kunigal Sateesh; Lakka Sajani S; Gondi Christopher S; Estes Norman; Rao Jasti S
RNAi-mediated downregulation of urokinase plasminogen activator receptor and matrix metalloprotease-9 in human breast cancer cells results in decreased tumor invasion, angiogenesis and growth.
International journal of cancer. Journal international du cancer 2007;121(10):2307-16.
2007: Gondi Christopher S; Lakka Sajani S; Dinh Dzung H; Olivero William C; Gujrati Meena; Rao Jasti S
Intraperitoneal injection of a hairpin RNA-expressing plasmid targeting urokinase-type plasminogen activator (uPA) receptor and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(14):4051-60.
2007: Rao Jasti S; Bhoopathi Praveen; Chetty Chandramu; Gujrati Meena; Lakka Sajani S
MMP-9 short interfering RNA induced senescence resulting in inhibition of medulloblastoma growth via p16(INK4a) and mitogen-activated protein kinase pathway.
Cancer research 2007;67(10):4956-64.
2007: Nalabothula Narasimharao; Lakka Sajani S; Dinh Dzung H; Gujrati Meena; Olivero William C; Rao Jasti S
Sense p16 and antisense uPAR bicistronic construct inhibits angiogenesis and induces glioma cell death.
International journal of oncology 2007;30(3):669-78.
2006: Kunigal Sateesh; Gondi Christopher S; Gujrati Meena; Lakka Sajani S; Dinh Dzung H; Olivero William C; Rao Jasti S
SPARC-induced migration of glioblastoma cell lines via uPA-uPAR signaling and activation of small GTPase RhoA.
International journal of oncology 2006;29(6):1349-57.
2006: Chetty Chandramu; Bhoopathi Praveen; Joseph Pushpa; Chittivelu Subramanyam; Rao Jasti S; Lakka Sajani
Adenovirus-mediated small interfering RNA against matrix metalloproteinase-2 suppresses tumor growth and lung metastasis in mice.
Molecular cancer therapeutics 2006;5(9):2289-99.
2006: Subramanian Ramesh; Gondi Christopher S; Lakka Sajani S; Jutla Aman; Rao Jasti S
siRNA-mediated simultaneous downregulation of uPA and its receptor inhibits angiogenesis and invasiveness triggering apoptosis in breast cancer cells.
International journal of oncology 2006;28(4):831-9.
2005: Lakka Sajani S; Gondi Christopher S; Rao Jasti S
Proteases and glioma angiogenesis.
Brain pathology (Zurich, Switzerland) 2005;15(4):327-41.
2005: Pulukuri Sai MuraliKrishna; Gondi Christopher S; Lakka Sajani S; Jutla Aman; Estes Norman; Gujrati Meena; Rao Jasti S
RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo.
The Journal of biological chemistry 2005;280(43):36529-40.
2005: Rao Jasti S; Gondi Christopher; Chetty Chandramu; Chittivelu Subramanyam; Joseph Pushpa A; Lakka Sajani S
Inhibition of invasion, angiogenesis, tumor growth, and metastasis by adenovirus-mediated transfer of antisense uPAR and MMP-9 in non-small cell lung cancer cells.
Molecular cancer therapeutics 2005;4(9):1399-408.
2005: Lakka Sajani S; Gondi Christopher S; Dinh Dzung H; Olivero William C; Gujrati Meena; Rao Velidi H; Sioka Chrissa; Rao Jasti S
Specific interference of urokinase-type plasminogen activator receptor and matrix metalloproteinase-9 gene expression induced by double-stranded RNA results in decreased invasion, tumor growth, and angiogenesis in gliomas.
The Journal of biological chemistry 2005;280(23):21882-92.
2004: Jadhav Unmesh; Chigurupati Srinivasulu; Lakka Sajani S; Mohanam Sanjeeva
Inhibition of matrix metalloproteinase-9 reduces in vitro invasion and angiogenesis in human microvascular endothelial cells.
International journal of oncology 2004;25(5):1407-14.
2004: Gondi Christopher S; Lakka Sajani S; Dinh Dzung H; Olivero William C; Gujrati Meena; Rao Jasti S
RNAi-mediated inhibition of cathepsin B and uPAR leads to decreased cell invasion, angiogenesis and tumor growth in gliomas.
Oncogene 2004;23(52):8486-96.
2004: Gondi Christopher S; Lakka Sajani S; Yanamandra Niranjan; Olivero William C; Dinh Dzung H; Gujrati Meena; Tung C H; Weissleder Ralph; Rao Jasti S
Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas.
Cancer research 2004;64(12):4069-77.
2004: Lakka Sajani S; Gondi Christopher S; Yanamandra Niranjan; Olivero William C; Dinh Dzung H; Gujrati Meena; Rao Jasti S
Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis.
Oncogene 2004;23(27):4681-9.
2003: Gondi Christopher S; Lakka Sajani S; Yanamandra Niranjan; Siddique Khawar; Dinh Dzung H; Olivero William C; Gujrati Meena; Rao Jasti S
Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis.
Oncogene 2003;22(38):5967-75.
2003: Konduri Santhi D; Srivenugopal Kalkunte S; Yanamandra Niranjan; Dinh Dzung H; Olivero William C; Gujrati Meena; Foster Donald C; Kisiel Walter; Ali-Osman Francis; Kondraganti Shakuntala; Lakka Sajani S; Rao Jasti S
Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an inhibitor of matrix metalloproteinases in human glioma cells.
Oncogene 2003;22(29):4509-16.
2003: Chandrasekar Nirmala; Mohanam Sanjeeva; Lakka S Sajani; Dinh Dzung H; Olivero William C; Gujrati Meena; Rao Jasti S
Glial cell-induced endothelial morphogenesis is inhibited by interfering with extracellular signal-regulated kinase signaling.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(6):2342-9.
2003: Lakka Sajani S; Gondi Christopher S; Yanamandra Niranjan; Dinh Dzung H; Olivero William C; Gujrati Meena; Rao Jasti S
Synergistic down-regulation of urokinase plasminogen activator receptor and matrix metalloproteinase-9 in SNB19 glioblastoma cells efficiently inhibits glioma cell invasion, angiogenesis, and tumor growth.
Cancer research 2003;63(10):2454-61.
2002: Lakka Sajani S; Rajan Mannari; Gondi Christopher; Yanamandra Niranjan; Chandrasekar Nirmala; Jasti Sushma L; Adachi Yoshiaki; Siddique Khawar; Gujrati Meena; Olivero William; Dinh Dzung H; Kouraklis Gregory; Kyritsis Athanassios P; Rao Jasti S
Adenovirus-mediated expression of antisense MMP-9 in glioma cells inhibits tumor growth and invasion.
Oncogene 2002;21(52):8011-9.
2002: Lakka Sajani S; Jasti Sushma L; Gondi Christopher; Boyd Douglas; Chandrasekar Nirmala; Dinh Dzung H; Olivero William C; Gujrati Meena; Rao Jasti S
Downregulation of MMP-9 in ERK-mutated stable transfectants inhibits glioma invasion in vitro.
Oncogene 2002;21(36):5601-8.
2002: Adachi Yoshiaki; Chandrasekar Nirmala; Kin Yoshiaki; Lakka Sajani S; Mohanam Sanjeeva; Yanamandra Niranjan; Mohan Pamarthi M; Fuller Gregory N; Fang Bingliang; Fueyo Juan; Dinh Dzung H; Olivero William C; Tamiya Takashi; Ohmoto Takashi; Kyritsis Anthanassios P; Rao Jasti S
Suppression of glioma invasion and growth by adenovirus-mediated delivery of a bicistronic construct containing antisense uPAR and sense p16 gene sequences.
Oncogene 2002;21(1):87-95.
2001: Adachi Y; Lakka S S; Chandrasekar N; Yanamandra N; Gondi C S; Mohanam S; Dinh D H; Olivero W C; Gujrati M; Tamiya T; Ohmoto T; Kouraklis G; Aggarwal B; Rao J S
Down-regulation of integrin alpha(v)beta(3) expression and integrin-mediated signaling in glioma cells by adenovirus-mediated transfer of antisense urokinase-type plasminogen activator receptor (uPAR) and sense p16 genes.
The Journal of biological chemistry 2001;276(50):47171-7.
2001: Konduri S D; Rao C N; Chandrasekar N; Tasiou A; Mohanam S; Kin Y; Lakka S S; Dinh D; Olivero W C; Gujrati M; Foster D C; Kisiel W; Rao J S
A novel function of tissue factor pathway inhibitor-2 (TFPI-2) in human glioma invasion.
Oncogene 2001;20(47):6938-45.
2001: Konduri S; Lakka S S; Tasiou A; Yanamandra N; Gondi C S; Dinh D H; Olivero W C; Gujrati M; Rao J S
Elevated levels of cathepsin B in human glioblastoma cell lines.
International journal of oncology 2001;19(3):519-24.
2001: Mohanam S; Jasti S L; Kondraganti S R; Chandrasekar N; Kin Y; Fuller G N; Lakka S S; Kyritsis A P; Dinh D H; Olivero W C; Gujrati M; Yung W K; Rao J S
Stable transfection of urokinase-type plasminogen activator antisense construct modulates invasion of human glioblastoma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(8):2519-26.
2001: Mohanam S; Jasti S L; Kondraganti S R; Chandrasekar N; Lakka S S; Kin Y; Fuller G N; Yung A W; Kyritsis A P; Dinh D H; Olivero W C; Gujrati M; Ali-Osman F; Rao J S
Down-regulation of cathepsin B expression impairs the invasive and tumorigenic potential of human glioblastoma cells.
Oncogene 2001;20(28):3665-73.
2001: Lakka S S; Rajagopal R; Rajan M K; Mohan P M; Adachi Y; Dinh D H; Olivero W C; Gujrati M; Ali-Osman F; Roth J A; Yung W K; Kyritsis A P; Rao J S
Adenovirus-mediated antisense urokinase-type plasminogen activator receptor gene transfer reduces tumor cell invasion and metastasis in non-small cell lung cancer cell lines.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(4):1087-93.
2001: Rao C N; Lakka S S; Kin Y; Konduri S D; Fuller G N; Mohanam S; Rao J S
Expression of tissue factor pathway inhibitor 2 inversely correlates during the progression of human gliomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3):570-6.
2001: Bhattacharya A; Lakka S S; Mohanam S; Boyd D; Rao J S
Regulation of the urokinase-type plasminogen activator receptor gene in different grades of human glioma cell lines.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(2):267-76.
2001: Lakka S S; Bhattacharya A; Mohanam S; Boyd D; Rao J S
Regulation of the uPA gene in various grades of human glioma cells.
International journal of oncology 2001;18(1):71-9.
2000: Kondraganti S; Mohanam S; Chintala S K; Kin Y; Jasti S L; Nirmala C; Lakka S S; Adachi Y; Kyritsis A P; Ali-Osman F; Sawaya R; Fuller G N; Rao J S
Selective suppression of matrix metalloproteinase-9 in human glioblastoma cells by antisense gene transfer impairs glioblastoma cell invasion.
Cancer research 2000;60(24):6851-5.
2000: Lakka S S; Jasti S L; Kyritsis A P; Yung W K; Ali-Osman F; Nicolson G L; Rao J S
Regulation of MMP-9 (type IV collagenase) production and invasiveness in gliomas by the extracellular signal-regulated kinase and jun amino-terminal kinase signaling cascades.
Clinical & experimental metastasis 2000;18(3):245-52.
2000: Lakka S S; Konduri S D; Mohanam S; Nicolson G L; Rao J S
In vitro modulation of human lung cancer cell line invasiveness by antisense cDNA of tissue factor pathway inhibitor-2.
Clinical & experimental metastasis 2000;18(3):239-44.
1999: Liu Y; Stack S M; Lakka S S; Khan A J; Woodley D T; Rao J S; Rao C N
Matrix localization of tissue factor pathway inhibitor-2/matrix-associated serine protease inhibitor (TFPI-2/MSPI) involves arginine-mediated ionic interactions with heparin and dermatan sulfate: heparin accelerates the activity of TFPI-2/MSPI toward plasmin.
Archives of biochemistry and biophysics 1999;370(1):112-8.
1999: Mohan P M; Chintala S K; Mohanam S; Gladson C L; Kim E S; Gokaslan Z L; Lakka S S; Roth J A; Fang B; Sawaya R; Kyritsis A P; Rao J S
Adenovirus-mediated delivery of antisense gene to urokinase-type plasminogen activator receptor suppresses glioma invasion and tumor growth.
Cancer research 1999;59(14):3369-73.
1999: Mohan P M; Lakka S S; Mohanam S; Kin Y; Sawaya R; Kyritsis A P; Nicolson G L; Rao J S
Downregulation of the urokinase-type plasminogen activator receptor through inhibition of translation by antisense oligonucleotide suppresses invasion of human glioblastoma cells.
Clinical & experimental metastasis 1999;17(7):617-21.

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