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Bachchu Lal

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TOP 3
Prakash Rath; SHULI XIA; Yunqing Li; Olutobi Ajala; Jin Kim; Bachchu Lal; John Laterra
In Vivo c-Met Pathway Inhibition Depletes Human Glioma Xenografts of Tumor-Propagating Stem-Like Cells.
S D Wang; C R Goodwin; Bachchu Lal; John Laterra; Y Li; P Rath; J-P Richard; SHULI XIA
EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase.
Elena Victoria Rosca; Aleksander S Popel; Jacob E Koskimaki; Bachchu Lal; John Laterra
Collagen IV and CXC chemokine-derived antiangiogenic peptides suppress glioma xenograft growth.

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All Publications

2013: Prakash Rath; SHULI XIA; Yunqing Li; Olutobi Ajala; Jin Kim; Bachchu Lal; John Laterra
In Vivo c-Met Pathway Inhibition Depletes Human Glioma Xenografts of Tumor-Propagating Stem-Like Cells.
Translational oncology 2013;6(2):104-11.
2012: S D Wang; C R Goodwin; Bachchu Lal; John Laterra; Y Li; P Rath; J-P Richard; SHULI XIA
EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase.
Oncogene 2012;31(50):5132-43.
2012: Elena Victoria Rosca; Aleksander S Popel; Jacob E Koskimaki; Bachchu Lal; John Laterra
Collagen IV and CXC chemokine-derived antiangiogenic peptides suppress glioma xenograft growth.
Anti-cancer drugs 2012;23(7):706-12.
2012: Silun Wang; Kun Yan; Michael Armour; Yifei Chen; ERIC FORD; Bachchu Lal; John Laterra; ERIK TRYGGESTAD; Jinyuan Zhou
Evaluation of radiation necrosis and malignant glioma in rat models using diffusion tensor MR imaging.
Journal of neuro-oncology 2012;107(1):51-60.
2011: Rachel Grossman; Lee Hwang; Kashi Javaherian; Bachchu Lal; Betty M. Tyler; Patti Zadnik; Henry Brem
Improvement in the standard treatment for experimental glioma by fusing antibody Fc domain to endostatin.
Journal of neurosurgery 2011;115(6):1139-46.
2011: C Rory Goodwin; Sandra Ho; Bachchu Lal; Alexandra Taeger; Crystal L Woodard; SHULI XIA; Xin Zhou; John Laterra
PTEN reconstitution alters glioma responses to c-Met pathway inhibition.
Anti-cancer drugs 2011;22(9):905-12.
2011: M Ying; C R Goodwin; Hugo Guerrero-Cazares; Bachchu Lal; John Laterra; A QUINONES-HINOJOSA; Y Sang; P Sun; Shengdian Wang; SHULI XIA
Regulation of glioblastoma stem cells by retinoic acid: role for Notch pathway inhibition.
Oncogene 2011;30(31):3454-67.
2011: Yunqing Li; A QUINONES-HINOJOSA; Yingying Sang; Bjorn Scheffler; Daniel Trageser; SHULI XIA; Mingyao Ying; Charles G Eberhart; Martin Glas; Hugo Guerrero-Cázares; Bachchu Lal; Angela Li; John Laterra
c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(24):9951-6.
2011: Jinyuan Zhou; ERIK TRYGGESTAD; Zhibo Wen; Bachchu Lal; Tingting Zhou; Rachel Grossman; Silun Wang; Kun Yan; DE-XUE FU; ERIC FORD; Betty M. Tyler; Jaishri Blakeley; John Laterra; Peter C M van Zijl
Differentiation between glioma and radiation necrosis using molecular magnetic resonance imaging of endogenous proteins and peptides.
Nature medicine 2011;17(1):130-4.
2010: C Rory Goodwin; Bachchu Lal; Xin Zhou; Sandra Ho; SHULI XIA; Alexandra Taeger; Jamie Murray; John Laterra
Cyr61 mediates hepatocyte growth factor-dependent tumor cell growth, migration, and Akt activation.
Cancer research 2010;70(7):2932-41.
2009: Zhengtong Pei; Peng Sun; Peng Huang; Bachchu Lal; John Laterra; Paul A Watkins
Acyl-CoA synthetase VL3 knockdown inhibits human glioma cell proliferation and tumorigenicity.
Cancer research 2009;69(24):9175-82.
2009: Bachchu Lal; C Rory Goodwin; Yingying Sang; Catherine A Foss; Kathrine Cornet; Sameena Muzamil; Martin G Pomper; Jin Kim; John Laterra
EGFRvIII and c-Met pathway inhibitors synergize against PTEN-null/EGFRvIII+ glioblastoma xenografts.
Molecular cancer therapeutics 2009;8(7):1751-60.
2009: Peng Sun; SHULI XIA; Bachchu Lal; Charles G Eberhart; A QUINONES-HINOJOSA; Jarek Maciaczyk; William Matsui; Francesco DiMeco; Sara M Piccirillo; Angelo L Vescovi; John Laterra
DNER, an epigenetically modulated gene, regulates glioblastoma-derived neurosphere cell differentiation and tumor propagation.
Stem cells (Dayton, Ohio) 2009;27(7):1473-86.
2008: Mandy J Binning; Toba Niazi; Carolyn A Pedone; Bachchu Lal; Charles G Eberhart; K Jin Kim; John Laterra; Daniel W Fults
Hepatocyte growth factor and sonic Hedgehog expression in cerebellar neural progenitor cells costimulate medulloblastoma initiation and growth.
Cancer research 2008;68(19):7838-45.
2008: Amandeep Salhotra; Bachchu Lal; John Laterra; Phillip Zhe Sun; Peter C M van Zijl; Jinyuan Zhou
Amide proton transfer imaging of 9L gliosarcoma and human glioblastoma xenografts.
NMR in biomedicine 2008;21(5):489-97.
2008: Yunqing Li; Fadila Guessous; Sherwin Kwon; Manish Kumar; Opeyemi Ibidapo; Lauren Fuller; Elizabeth Johnson; Bachchu Lal; Isa M Hussaini; Yongde Bao; John Laterra; David Schiff; Roger Abounader
PTEN has tumor-promoting properties in the setting of gain-of-function p53 mutations.
Cancer research 2008;68(6):1723-31.
2008: Yunqing Li; Fadila Guessous; Elizabeth B Johnson; Charles G Eberhart; Xiao-Nan Li; Qing Shu; Shongshan Fan; Bachchu Lal; John Laterra; David Schiff; Roger Abounader
Functional and molecular interactions between the HGF/c-Met pathway and c-Myc in large-cell medulloblastoma.
Laboratory investigation; a journal of technical methods and pathology 2008;88(2):98-111.
2007: YIMAO ZHANG; Joseph Bressler; Jeff Neal; Bachchu Lal; Hyo-Eun C Bhang; John Laterra; Martin G Pomper
ABCG2/BCRP expression modulates D-Luciferin based bioluminescence imaging.
Cancer research 2007;67(19):9389-97.
2007: Jiangyang Zhang; Peter C M van Zijl; John Laterra; Amandeep Salhotra; Bachchu Lal; Susumu Mori; Jinyuan Zhou
Unique patterns of diffusion directionality in rat brain tumors revealed by high-resolution diffusion tensor MRI.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2007;58(3):454-62.
2006: K Jin Kim; Lihong Wang; Yi-Chi Su; G Yancey Gillespie; Amandeep Salhotra; Bachchu Lal; John Laterra
Systemic anti-hepatocyte growth factor monoclonal antibody therapy induces the regression of intracranial glioma xenografts.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(4):1292-8.
2005: Yunqing Li; Bachchu Lal; Sherwin Kwon; Xing Fan; Usha Saldanha; Thomas E Reznik; Eric B Kuchner; Charles G Eberhart; John Laterra; Roger Abounader
The scatter factor/hepatocyte growth factor: c-met pathway in human embryonal central nervous system tumor malignancy.
Cancer research 2005;65(20):9355-62.
2005: Bachchu Lal; SHULI XIA; Roger Abounader; John Laterra
Targeting the c-Met pathway potentiates glioblastoma responses to gamma-radiation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(12):4479-86.
2004: Mir Ahamed Hossain; Juliet C Russell; Sheila J Miknyoczki; Bruce Ruggeri; Bachchu Lal; John Laterra
Vascular endothelial growth factor mediates vasogenic edema in acute lead encephalopathy.
Annals of neurology 2004;55(5):660-7.
2004: Xun Song; Carey Pope; Ramesh Murthy; Jamaluddin Shaikh; Bachchu Lal; Joseph Bressler
Interactive effects of paraoxon and pyridostigmine on blood-brain barrier integrity and cholinergic toxicity.
Toxicological sciences : an official journal of the Society of Toxicology 2004;78(2):241-7.
2003: Jinyuan Zhou; Bachchu Lal; David Allen Wilson; John Laterra; Peter C M van Zijl
Amide proton transfer (APT) contrast for imaging of brain tumors.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2003;50(6):1120-6.
2002: Roger Abounader; Bachchu Lal; Carey Luddy; Gary Koe; Beverly Davidson; Eliot M Rosen; John Laterra
In vivo targeting of SF/HGF and c-met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(1):108-10.
2000: Christopher Guerin; Carey Luddy; Roger Abounader; Bachchu Lal; John Laterra
Glioma inhibition by HGF/NK2, an antagonist of scatter factor/hepatocyte growth factor.
Biochemical and biophysical research communications 2000;273(1):287-93.
1999: Roger Abounader; Srikanth Ranganathan; Bachchu Lal; KE Fielding; AA Book; Harry C Dietz; Peter C Burger; John Laterra
Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression.
Journal of the National Cancer Institute 1999;91(18):1548-56.
1996: M Nam; Peter V Johnston; Bachchu Lal; R Indurti; Mary Ann Wilson; John Laterra
Endothelial cell-based cytokine gene delivery inhibits 9L glioma growth in vivo.
Brain research 1996;731(1-2):161-70.
1996: Bachchu Lal; GARY GOLDSTEIN; Joseph Bressler
Role of anion exchange and thiol groups in the regulation of potassium efflux by lead in human erythrocytes.
Journal of cellular physiology 1996;167(2):222-8.
1994: Bachchu Lal; R R Indurti; P O Couraud; GARY GOLDSTEIN; John Laterra
Endothelial cell implantation and survival within experimental gliomas.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(21):9695-9.
1994: Bachchu Lal; Mitchell A Cahan; P O Couraud; GARY GOLDSTEIN; John Laterra
Development of endogenous beta-galactosidase and autofluorescence in rat brain microvessels: implications for cell tracking and gene transfer studies.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1994;42(7):953-6.