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Jonathan Lamb

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Harriet B Taylor; Charlotte Barthen; Simon B Brown; Laurence Bugeon; Maxime Huvet; Paul D W Kirk; Jonathan R Lamb; Juliane Liepe; Michael P H Stumpf; Margaret J Dallman
P38 and JNK have opposing effects on persistence of in vivo leukocyte migration in zebrafish.
Fränze Progatzky; Andreas Radbruch; Harriet Taylor; Laurence Bugeon; Sorcha Cassidy; Margaret J Dallman; Jonathan R Lamb
The role of Nfil3 in zebrafish hematopoiesis.
Lingling Chen; Margaret J Dallman; Jonathan R Lamb; James McGinty; Harriet B Taylor; Laurence Bugeon; Paul M W French
Incorporation of an experimentally determined MTF for spatial frequency filtering and deconvolution during optical projection tomography reconstruction.

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2013: Harriet B Taylor; Charlotte Barthen; Simon B Brown; Laurence Bugeon; Maxime Huvet; Paul D W Kirk; Jonathan R Lamb; Juliane Liepe; Michael P H Stumpf; Margaret J Dallman
P38 and JNK have opposing effects on persistence of in vivo leukocyte migration in zebrafish.
Immunology and cell biology 2013;91(1):60-9.
2012: Fränze Progatzky; Andreas Radbruch; Harriet Taylor; Laurence Bugeon; Sorcha Cassidy; Margaret J Dallman; Jonathan R Lamb
The role of Nfil3 in zebrafish hematopoiesis.
Developmental and comparative immunology 2012;38(1):187-92.
2012: Lingling Chen; Margaret J Dallman; Jonathan R Lamb; James McGinty; Harriet B Taylor; Laurence Bugeon; Paul M W French
Incorporation of an experimentally determined MTF for spatial frequency filtering and deconvolution during optical projection tomography reconstruction.
Optics express 2012;20(7):7323-37.
2012: Juliane Liepe; Harriet Taylor; Thomas Thorne; Chris P Barnes; Laurence Bugeon; Margaret J Dallman; Maxime Huvet; Jonathan R Lamb; Michael P H Stumpf
Calibrating spatio-temporal models of leukocyte dynamics against in vivo live-imaging data using approximate Bayesian computation.
Integrative biology : quantitative biosciences from nano to macro 2012;4(3):335-45.
2012: Daxu Li; Vincent C H Lui; Jiao Peng; Paul K H Tam; Julia Y S Tsang; Aimin Xu; Jiang Zhu; Yee Kwan Chan; Derek H H Ho; Jonathan R Lamb; Yan Chen
Adiponectin mediated MHC class II mismatched cardiac graft rejection in mice is IL-4 dependent.
PloS one 2012;7(11):e48893.
2011: Charlotte L Weller; Sarah J Collington; Tim Williams; Jonathan R Lamb
Mast cells in health and disease.
Clinical science (London, England : 1979) 2011;120(11):473-84.
2011: Carol Pridgeon; Laurence Bugeon; Louise Donnelly; Ursula Straschil; Susan J Tudhope; Peter Fenwick; Jonathan R Lamb; Peter J Barnes; Margaret J Dallman
Regulation of IL-17 in chronic inflammation in the human lung.
Clinical science (London, England : 1979) 2011;120(12):515-24.
2011: James McGinty; Harriet B Taylor; Lingling Chen; Laurence Bugeon; Jonathan R Lamb; Margaret J Dallman; Paul M W French
In vivo fluorescence lifetime optical projection tomography.
Biomedical optics express 2011;2(5):1340-50.
2009: Jingti Deng; Christian H James; Lisa Patel; Alberto Smith; Kevin G Burnand; Hassan Rahmoune; Jonathan R Lamb; Bill Davis
Human tribbles homologue 2 is expressed in unstable regions of carotid plaques and regulates macrophage IL-10 in vitro.
Clinical science (London, England : 1979) 2009;116(3):241-8.
2008: Yan Liu; Yan Chen; Fing Qin Liu; Jonathan R Lamb; Paul K H Tam
Combined treatment with triptolide and rapamycin prolongs graft survival in a mouse model of cardiac transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 2008;21(5):483-94.
2008: Yan Chen; Christy S K Kam; Feng Qin Liu; Yan Liu; Vincent C H Lui; Jonathan R Lamb; Paul K H Tam
LPS-induced up-regulation of TGF-beta receptor 1 is associated with TNF-alpha expression in human monocyte-derived macrophages.
Journal of leukocyte biology 2008;83(5):1165-73.
2008: Feng Qin Liu; Yan Liu; Vincent C H Lui; Jonathan R Lamb; Paul K H Tam; Yan Chen
Hypoxia modulates lipopolysaccharide induced TNF-alpha expression in murine macrophages.
Experimental cell research 2008;314(6):1327-36.
2007: Yan Liu; Yan Chen; Jonathan R Lamb; Paul K H Tam
Triptolide, a component of Chinese herbal medicine, modulates the functional phenotype of dendritic cells.
Transplantation 2007;84(11):1517-26.
2007: Paul W Thompson; Andrew I Bayliffe; Andrew P Warren; Jonathan R Lamb
Interleukin-10 is upregulated by nanomolar rosiglitazone treatment of mature dendritic cells and human CD4+ T cells.
Cytokine 2007;39(3):184-91.
2007: Yan Chen; Yan Liu; Zhengwei Yuan; Lina Tian; Margaret J Dallman; Paul W Thompson; Paul K H Tam; Jonathan R Lamb
Rosiglitazone suppresses cyclosporin-induced chronic transplant dysfunction and prolongs survival of rat cardiac allografts.
Transplantation 2007;83(12):1602-10.
2007: Yan Chen; Xiaosong Li; Lina Tian; Vincent C H Lui; Margaret J Dallman; Jonathan R Lamb; Paul K H Tam
Inhibition of sonic hedgehog signaling reduces chronic rejection and prolongs allograft survival in a rat orthotopic small bowel transplantation model.
Transplantation 2007;83(10):1351-7.
2005: Mark Wilson; Matthew D Taylor; Adam Balic; Constance A M Finney; Jonathan R Lamb; Rick M Maizels
Suppression of allergic airway inflammation by helminth-induced regulatory T cells.
The Journal of experimental medicine 2005;202(9):1199-212.
2005: Carolyn E Fisher; Sharon A Ahmad; Paul M Fitch; Jonathan R Lamb; Sarah E M Howie
FITC-induced murine pulmonary inflammation: CC10 up-regulation and concurrent Shh expression.
Cell biology international 2005;29(10):868-76.
2005: Elizabeth R Jarman; Karen A L Tan; Jonathan R Lamb
Transgenic mice expressing the T cell antigen receptor specific for an immunodominant epitope of a major allergen of house dust mite develop an asthmatic phenotype on exposure of the airways to allergen.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2005;35(7):960-9.
2005: Margaret J Dallman; Emma Smith; Robert A Benson; Jonathan R Lamb
Notch: control of lymphocyte differentiation in the periphery.
Current opinion in immunology 2005;17(3):259-66.
2005: Robert A Benson; Karen Adamson; Marta Corsin-Jimenez; Julia V Marley; Karen A Wahl; Jonathan R Lamb; Sarah E M Howie
Notch1 co-localizes with CD4 on activated T cells and Notch signaling is required for IL-10 production.
European journal of immunology 2005;35(3):859-69.
2004: Elizabeth R Jarman; Jonathan R Lamb
Reversal of established CD4+ type 2 T helper-mediated allergic airway inflammation and eosinophilia by therapeutic treatment with DNA vaccines limits progression towards chronic inflammation and remodelling.
Immunology 2004;112(4):631-42.
2004: Robert A Benson; Jacqueline A Lowrey; Jonathan R Lamb; Sarah E M Howie
The Notch and Sonic hedgehog signalling pathways in immunity.
Molecular immunology 2004;41(6-7):715-25.
2004: Karen Adamson; Simon H S Pearce; Jonathan R Lamb; J R Seckl; Sarah E M Howie
A comparative study of mRNA and protein expression of the autoimmune regulator gene (Aire) in embryonic and adult murine tissues.
The Journal of pathology 2004;202(2):180-7.
2004: Lina Tian; Liwei Lu; Zhengwei Yuan; Jonathan R Lamb; Paul K H Tam
Acceleration of apoptosis in CD4+CD8+ thymocytes by rapamycin accompanied by increased CD4+CD25+ T cells in the periphery.
Transplantation 2004;77(2):183-9.
2004: Sonia J Wakelin; Lorna Marson; Sarah E M Howie; James Garden; Jonathan R Lamb; John L R Forsythe
The role of vascular endothelial growth factor in the kidney in health and disease.
Nephron. Physiology 2004;98(3):p73-9.
2003: Kenneth K Wong; Matthew J Carpenter; Lesley L Young; Susan J Walker; Grahame J Mckenzie; Alyson J Rust; George A Ward; Laura Packwood; Karen A Wahl; Luc Delriviere; Gerard F Hoyne; Paul Gibbs; Brian R Champion; Jonathan R Lamb; Margaret J Dallman
Notch ligation by Delta1 inhibits peripheral immune responses to transplantation antigens by a CD8+ cell-dependent mechanism.
The Journal of clinical investigation 2003;112(11):1741-50.
2003: Alexander Faith; David F Richards; Adrienne Verhoef; Jonathan R Lamb; Tak H Lee; Catherine M Hawrylowicz
Impaired secretion of interleukin-4 and interleukin-13 by allergen-specific T cells correlates with defective nuclear expression of NF-AT2 and jun B: relevance to immunotherapy.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(9):1209-15.
2003: Grahame J Mckenzie; Lesley L Young; Emmanuel Briend; Jonathan R Lamb; Margaret J Dallman; Brian R Champion
Notch signalling in the regulation of peripheral T-cell function.
Seminars in cell & developmental biology 2003;14(2):127-34.
2003: Gareth A Stewart; Gerard F Hoyne; Sharon A Ahmad; Elizabeth R Jarman; William A H Wallace; David J Harrison; Christopher Haslett; Jonathan R Lamb; Sarah E M Howie
Expression of the developmental Sonic hedgehog (Shh) signalling pathway is up-regulated in chronic lung fibrosis and the Shh receptor patched 1 is present in circulating T lymphocytes.
The Journal of pathology 2003;199(4):488-95.
2003: Gillian Hall; Christian G Houghton; Janne Uldal Rahbek; Jonathan R Lamb; Elizabeth R Jarman
Suppression of allergen reactive Th2 mediated responses and pulmonary eosinophilia by intranasal administration of an immunodominant peptide is linked to IL-10 production.
Vaccine 2003;21(5-6):549-61.
2003: Margaret J Dallman; Brian R Champion; Jonathan R Lamb
Notch signalling in the peripheral immune system.
Novartis Foundation symposium 2003;252():268-76; discussion 276-8.
2002: Monia Draghi; Elizabeth R Jarman; Renata Grifantini; Luisa Galli-Stampino; Jonathan R Lamb; Nicholas M Valiante; Guido Grandi
Different profile of CD8+ effector T cells induced in Der p 1-allergic and naïve mice by DNA vaccination.
European journal of immunology 2002;32(12):3720-8.
2002: Gillian Hall; Lise Lund; Jonathan R Lamb; Elizabeth R Jarman
Kinetics and mode of peptide delivery via the respiratory mucosa determine the outcome of activation versus TH2 immunity in allergic inflammation of the airways.
The Journal of allergy and clinical immunology 2002;110(6):883-90.
2002: Gareth A Stewart; Jacqueline A Lowrey; Sonia J Wakelin; Paul M Fitch; Susannah Lindey; Margaret J Dallman; Jonathan R Lamb; Sarah E M Howie
Sonic hedgehog signaling modulates activation of and cytokine production by human peripheral CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5451-7.
2002: Nigel D L Savage; Stephen H Harris; Adriano G Rossi; Bernadette De Silva; Sarah E M Howie; Guy T Layton; Jonathan R Lamb
Inhibition of TCR-mediated shedding of L-selectin (CD62L) on human and mouse CD4+ T cells by metalloproteinase inhibition: analysis of the regulation of Th1/Th2 function.
European journal of immunology 2002;32(10):2905-14.
2002: Tim Nuttall; Pamela A Knight; Sybil M McAleese; Jonathan R Lamb; Peter B Hill
T-helper 1, T-helper 2 and immunosuppressive cytokines in canine atopic dermatitis.
Veterinary immunology and immunopathology 2002;87(3-4):379-84.
2002: Jacqueline A Lowrey; Gareth A Stewart; Susannah Lindey; Gerard F Hoyne; Margaret J Dallman; Sarah E M Howie; Jonathan R Lamb
Sonic hedgehog promotes cell cycle progression in activated peripheral CD4(+) T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(4):1869-75.
2002: Tim Nuttall; Pamela A Knight; Sybil M McAleese; Jonathan R Lamb; Peter B Hill
Expression of Th1, Th2 and immunosuppressive cytokine gene transcripts in canine atopic dermatitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2002;32(5):789-95.
2002: Sumeena Bhatia; Sangita Mukhopadhyay; Elizabeth R Jarman; Gillian Hall; Anna George; Sandip Kumar Basu; Satyajit Rath; Jonathan R Lamb; Vineeta Bal
Scavenger receptor-specific allergen delivery elicits IFN-gamma-dominated immunity and directs established TH2-dominated responses to a nonallergic phenotype.
The Journal of allergy and clinical immunology 2002;109(2):321-8.
2002: Tim Nuttall; Alan Pemberton; Jonathan R Lamb; Peter B Hill
Peripheral blood mononuclear cell responses to major and minor Dermatophagoides allergens in canine atopic dermatitis.
Veterinary immunology and immunopathology 2002;84(3-4):143-50.
2001: Tim Nuttall; Jonathan R Lamb; Peter B Hill
Peripheral blood mononuclear cell responses to Dermatophagoides farinae in canine atopic dermatitis.
Veterinary immunology and immunopathology 2001;82(3-4):273-80.
2001: Gerard F Hoyne; Margaret J Dallman; Brian R Champion; Jonathan R Lamb
Notch signalling in the regulation of peripheral immunity.
Immunological reviews 2001;182():215-27.
2001: Tim Nuttall; Jonathan R Lamb; Peter B Hill
Characterisation of major and minor Dermatophagoides allergens in canine atopic dermatitis.
Research in veterinary science 2001;71(1):51-7.
2001: R Janssen; A Kruisselbrink; Linsy Hoogteijling; Jonathan R Lamb; Douglas B Young; JE Thole
Analysis of recombinant mycobacteria as T helper type 1 vaccines in an allergy challenge model.
Immunology 2001;102(4):441-9.
2001: Manir Ali; Frederique Ponchel; K E Wilson; M J Francis; X Wu; Adrienne Verhoef; Arthur W Boylston; douglas veale; Paul Emery; Alexander F Markham; Jonathan R Lamb; John D Isaacs
Rheumatoid arthritis synovial T cells regulate transcription of several genes associated with antigen-induced anergy.
The Journal of clinical investigation 2001;107(4):519-28.
2001: Chandrashekhar Pasare; Paushali Mukherjee; Adrienne Verhoef; P Bansal; S K Mendiratta; Anna George; Jonathan R Lamb; Satyajit Rath; Vineeta Bal
T cells in mice expressing a transgenic human TCR beta chain get positively selected but cannot be activated in the periphery by signaling through TCR.
International immunology 2001;13(1):53-62.
2000: Gerard F Hoyne; K Tan; Marta Corsin-Jimenez; Karen A Wahl; M Stewart; Sarah E M Howie; Jonathan R Lamb
Immunological tolerance to inhaled antigen.
American journal of respiratory and critical care medicine 2000;162(4 Pt 2):S169-74.
2000: Gerard F Hoyne; Margaret J Dallman; Jonathan R Lamb
T-cell regulation of peripheral tolerance and immunity: the potential role for Notch signalling.
Immunology 2000;100(3):281-8.
2000: P Pala; Adrienne Verhoef; Jonathan R Lamb; Peter J M Openshaw
Single cell analysis of cytokine expression kinetics by human CD4+ T-cell clones during activation or tolerance induction.
Immunology 2000;100(2):209-16.
2000: Adrienne Verhoef; Jonathan R Lamb
Threshold signaling of human Th0 cells in activation and anergy: modulation of effector function by altered TCR ligand.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(11):6034-40.
2000: Gerard F Hoyne; Isabelle le Roux; Marta Corsin-Jimenez; K Tan; J Dunne; LM Forsyth; Margaret J Dallman; M J Owen; David Ish-Horowicz; Jonathan R Lamb
Serrate1-induced notch signalling regulates the decision between immunity and tolerance made by peripheral CD4(+) T cells.
International immunology 2000;12(2):177-85.
1999: S Hirschberg; Guy T Layton; SJ Harris; Nigel D L Savage; Margaret J Dallman; Jonathan R Lamb
CD4(+) T cells induced by virus-like particles expressing a major T cell epitope down-regulate IL-5 production in an ongoing immune response to Der p 1 independently of IFN-gamma production.
International immunology 1999;11(12):1927-34.
1999: Daphne C Tsitoura; Rosemarie H Dekruyff; Jonathan R Lamb; Dale T Umetsu
Intranasal exposure to protein antigen induces immunological tolerance mediated by functionally disabled CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(5):2592-600.
1999: Gerard F Hoyne; Margaret J Dallman; Jonathan R Lamb
Linked suppression in peripheral T cell tolerance to the house dust mite derived allergen Der p 1.
International archives of allergy and immunology 1999;118(2-4):122-4.
1998: C Hetzel; R Janssen; S J Ely; N M Kristensen; K Bunting; Jonathan B Cooper; Jonathan R Lamb; Douglas B Young; JE Thole
An epitope delivery system for use with recombinant mycobacteria.
Infection and immunity 1998;66(8):3643-8.
1998: J L Lowrey; Nigel D L Savage; Deborah Palliser; Marta Corsin-Jimenez; LM Forsyth; G Hall; Susannah Lindey; Gareth A Stewart; Karen A L Tan; Gerard F Hoyne; Jonathan R Lamb
Induction of tolerance via the respiratory mucosa.
International archives of allergy and immunology 1998;116(2):93-102.
1998: Deborah Palliser; Jacqueline A Lowrey; Jonathan R Lamb; Gerard F Hoyne
T-cell response to inhaled antigen.
Chemical immunology 1998;71():161-77.
1997: Daphne C Tsitoura; C M Gelder; David M Kemeny; Jonathan R Lamb
Regulation of cytokine production by human Th0 cells following stimulation with peptide analogues: differential expression of TGF-beta in activation and anergy.
Immunology 1997;92(1):10-9.
1997: C E Edmead; Jonathan R Lamb; Gerard F Hoyne
The T cell surface protein, CD28.
The international journal of biochemistry & cell biology 1997;29(8-9):1053-7.
1997: Gerard F Hoyne; Andrew G Jarnicki; Wayne R Thomas; Jonathan R Lamb
Characterization of the specificity and duration of T cell tolerance to intranasally administered peptides in mice: a role for intramolecular epitope suppression.
International immunology 1997;9(8):1165-73.
1997: C Hetzel; R Janssen; S Ely; Douglas Young; Jonathan R Lamb; JE Thole
Use of peptides to selectively modulate CD4+ T-cell responses.
Biochemical Society transactions 1997;25(2):398-403.
1997: C Abou-Zeid; Marie-Pierre Gares; J Inwald; R Janssen; Ying Zhang; Douglas B Young; C Hetzel; Jonathan R Lamb; S L Baldwin; I M Orme; Vladimir V Yeremeev; Boris V Nikonenko; Alexander S Apt
Induction of a type 1 immune response to a recombinant antigen from Mycobacterium tuberculosis expressed in Mycobacterium vaccae.
Infection and immunity 1997;65(5):1856-62.
1997: Gerard F Hoyne; Jonathan R Lamb
Regulation of T cell function in mucosal tolerance.
Immunology and cell biology 1997;75(2):197-201.
1997: John D Hayball; Sarah Fidler; Deborah Palliser; AD Rees; Jonathan R Lamb; Richard A Lake
Tandem peptide epitopes facilitate CD4-dependent activation of T cell clones.
Immunology and cell biology 1997;75(2):148-53.
1997: SJ Harris; J F Roth; Nigel D L Savage; S A Woodrow; I K Hemingway; Gerard F Hoyne; Jonathan R Lamb; Guy T Layton
Prediction of murine MHC class I epitopes in a major house dust mite allergen and induction of T1-type CD8+ T cell responses.
International immunology 1997;9(2):273-80.
1997: Jonathan R Lamb; Daphne C Tsitoura; Gerard F Hoyne
Peptide mediated modulation of allergen specific immune responses.
Arbeiten aus dem Paul-Ehrlich-Institut (Bundesamt für Sera und Impfstoffe) zu Frankfurt a.M 1997;(91):14-20; discussion 20-1.
1996: D C Tsitoura; A Verhoef; C M Gelder; R E O'Hehir; Jonathan R Lamb
Altered T cell ligands derived from a major house dust mite allergen enhance IFN-gamma but not IL-4 production by human CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(5):2160-5.
1996: A Faith; H Yssel; R E O'Hehir; Jonathan R Lamb
Reversal of the inhibitory effects of HIV-gp120 on CD4+ T cells by stimulation through the CD28 pathway.
Clinical and experimental immunology 1996;105(2):225-30.
1996: C J Lord; Jonathan R Lamb
TH2 cells in allergic inflammation: a target of immunotherapy.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1996;26(7):756-65.
1996: N M Kristensen; Gerard F Hoyne; John D Hayball; C Hetzel; T Bourne; Jonathan R Lamb
Induction of T cell responses to the invariant chain derived peptide CLIP in mice immunized with the group 1 allergen of house dust mite.
International immunology 1996;8(7):1091-8.
1996: C M Gelder; Jonathan R Lamb; B A Askonas
Human CD4+ T-cell recognition of influenza A virus hemagglutinin after subunit vaccination.
Journal of virology 1996;70(7):4787-90.
1996: D C Tsitoura; W Holter; A Cerwenka; C M Gelder; Jonathan R Lamb
Induction of anergy in human T helper 0 cells by stimulation with altered T cell antigen receptor ligands.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(8):2801-8.
1996: Gerard F Hoyne; Jonathan R Lamb
Peptide-mediated regulation of the allergic immune response.
Immunology and cell biology 1996;74(2):180-6.
1996: Gerard F Hoyne; B A Askonas; C Hetzel; Wayne R Thomas; Jonathan R Lamb
Regulation of house dust mite responses by intranasally administered peptide: transient activation of CD4+ T cells precedes the development of tolerance in vivo.
International immunology 1996;8(3):335-42.
1996: C M Hawrylowicz; E R Jarman; L Guida; R E O'Hehir; Jonathan R Lamb
T-cell receptor peptides that inhibit the T-cell response to allergen induce transforming growth factor-beta 1 production.
The Journal of allergy and clinical immunology 1996;97(2):707-9.
1996: Jonathan R Lamb; R E O'Hehir
Peptide mediated regulation of allergen specific immune responses.
Advances in experimental medicine and biology 1996;409():451-6.
1996: R E O'Hehir; Richard A Lake; T J Schall; H Yssel; E Panagiotopoulou; Jonathan R Lamb
Regulation of cytokine and chemokine transcription in a human TH2 type T-cell clone during the induction phase of anergy.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1996;26(1):20-7.
1996: S D'Souza; Michael Levin; A Faith; H Yssel; B Bennett; Richard A Lake; I N Brown; Jonathan R Lamb
Defective antigen processing associated with familial disseminated mycobacteriosis.
Clinical and experimental immunology 1996;103(1):35-9.
1995: A Faith; J A Higgins; R E O'Hehir; Jonathan R Lamb
Differential dependence of TH-0, TH-1 and TH-2 CD4+ T cells on co-stimulatory activity provided by the accessory molecule LFA-1.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1995;25(12):1163-70.
1995: Gerard F Hoyne; N M Kristensen; H Yssel; Jonathan R Lamb
Peptide modulation of allergen-specific immune responses.
Current opinion in immunology 1995;7(6):757-61.
1995: C M Gelder; K I Welsh; A Faith; Jonathan R Lamb; B A Askonas
Human CD4+ T-cell repertoire of responses to influenza A virus hemagglutinin after recent natural infection.
Journal of virology 1995;69(12):7497-506.
1995: Jonathan R Lamb; A Faith; J A Higgins; A Verhoef; P Schneider; H Yssel; R E O'Hehir
Clonal analysis of CD4 mediated accessory function on the effector activity of human CD4+ T cell subsets.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1995;25(9):839-47.
1995: Jonathan R Lamb; J A Higgins; C Hetzel; John D Hayball; Richard A Lake; R E O'Hehir
The effects of changes at peptide residues contacting MHC class II T-cell receptor on antigen recognition and human Th0 cell effector function.
Immunology 1995;85(3):447-54.
1995: John D Hayball; R E O'Hehir; Jonathan R Lamb; Richard A Lake
The domain structure and functional relationships in the bacterial superantigen, SEB.
Biological chemistry Hoppe-Seyler 1995;376(5):303-9.
1995: C Hetzel; Gerard F Hoyne; Jonathan R Lamb
Peptide-mediated immunoregulation.
International archives of allergy and immunology 1995;107(1-3):275-7.
1995: D Wotton; J A Higgins; R E O'Hehir; Jonathan R Lamb; Richard A Lake
Differential induction of the NF-AT complex during restimulation and the induction of T-cell anergy.
Human immunology 1995;42(2):95-102.
1995: J A Higgins; Jonathan R Lamb; Richard A Lake; R E O'Hehir
Polyclonal and clonal analysis of human CD4+ T-lymphocyte responses to nut extracts.
Immunology 1995;84(1):91-7.
1994: E R Jarman; C M Hawrylowicz; E Panagiotopolou; R E O'Hehir; Jonathan R Lamb
Inhibition of human T-cell responses to house dust mite allergens by a T-cell receptor peptide.
The Journal of allergy and clinical immunology 1994;94(5):844-52.
1994: P H Hoeger; Mark Tepper; A Faith; J A Higgins; Jonathan R Lamb; Raif S Geha
Immunosuppressant deoxyspergualin inhibits antigen processing in monocytes.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(9):3908-16.
1994: Mark Larché; Gerard F Hoyne; Richard A Lake; Jonathan R Lamb
Immunological events underlying the induction of T cell non-responsiveness.
International archives of allergy and immunology 1994;104(3):211-5.
1994: J A Higgins; Christopher Thorpe; John D Hayball; R E O'Hehir; Jonathan R Lamb
Overlapping T-cell epitopes in the group I allergen of Dermatophagoides species restricted by HLA-DP and HLA-DR class II molecules.
The Journal of allergy and clinical immunology 1994;93(5):891-9.
1994: C M Jones; Richard A Lake; Jonathan R Lamb; A Faith
Degeneracy of T cell receptor recognition of an influenza virus hemagglutinin epitope restricted by HLA-DQ and -DR class II molecules.
European journal of immunology 1994;24(5):1137-42.
1994: John D Hayball; J H Robinson; R E O'Hehir; A Verhoef; Jonathan R Lamb; Richard A Lake
Identification of two binding sites in staphylococcal enterotoxin B that confer specificity for TCR V beta gene products.
International immunology 1994;6(2):199-211.
1993: J L Viney; H M Prosser; D B Palmer; Marie Lipoldova; Jonathan R Lamb; MJ Owen
Analysis of T cell repertoire and function in mice transgenic for the human V beta 3 TCR.
International immunology 1993;5(12):1541-9.
1993: R E O'Hehir; Gerard F Hoyne; Wayne R Thomas; Jonathan R Lamb
House dust mite allergy: from T-cell epitopes to immunotherapy.
European journal of clinical investigation 1993;23(12):763-72.
1993: A Verhoef; J A Higgins; Christopher Thorpe; S G Marsh; John D Hayball; Jonathan R Lamb; R E O'Hehir
Clonal analysis of the atopic immune response to the group 2 allergen of Dermatophagoides spp.: identification of HLA-DR and -DQ restricted T cell epitopes.
International immunology 1993;5(12):1589-97.
1993: Gerard F Hoyne; R E O'Hehir; D C Wraith; Wayne R Thomas; Jonathan R Lamb
Inhibition of T cell and antibody responses to house dust mite allergen by inhalation of the dominant T cell epitope in naive and sensitized mice.
The Journal of experimental medicine 1993;178(5):1783-8.
1993: R E O'Hehir; Jonathan R Lamb
Human in vitro experimental model for CD4+ T cell targeted immunotherapy to house dust mite.
Annals of allergy 1993;71(3):317-21.
1993: R E O'Hehir; A Verhoef; E Panagiotopoulou; S Keswani; John D Hayball; Wayne R Thomas; Jonathan R Lamb
Analysis of human T cell responses to the group II allergen of Dermatophagoides species: localization of major antigenic sites.
The Journal of allergy and clinical immunology 1993;92(1 Pt 1):105-13.
1993: Richard A Lake; R E O'Hehir; A Verhoef; Jonathan R Lamb
CD28 mRNA rapidly decays when activated T cells are functionally anergized with specific peptide.
International immunology 1993;5(5):461-6.
1992: J L Viney; H M Prosser; C R Hewitt; Jonathan R Lamb; MJ Owen
Generation of monoclonal antibodies against a human T cell receptor beta chain expressed in transgenic mice.
Hybridoma 1992;11(6):701-13.
1992: J A Higgins; Jonathan R Lamb; S G Marsh; S Tonks; John D Hayball; S Rosen-Bronson; J G Bodmer; R E O'Hehir
Peptide-induced nonresponsiveness of HLA-DP restricted human T cells reactive with Dermatophagoides spp. (house dust mite).
The Journal of allergy and clinical immunology 1992;90(5):749-56.
1992: C R Hewitt; Jonathan R Lamb; John D Hayball; M Hill; MJ Owen; R E O'Hehir
Major histocompatibility complex independent clonal T cell anergy by direct interaction of Staphylococcus aureus enterotoxin B with the T cell antigen receptor.
The Journal of experimental medicine 1992;175(6):1493-9.
1992: A Faith; R E O'Hehir; M Malkovsky; Jonathan R Lamb
Analysis of the basis of resistance and susceptibility of CD4+ T cells to human immunodeficiency virus (HIV)-gp120 induced anergy.
Immunology 1992;76(2):177-84.
1992: R E O'Hehir; Jonathan R Lamb
Strategies for modulating immunoglobulin E synthesis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1992;22(1):7-10.
1991: L D Barber; V Bal; Jonathan R Lamb; Robyn E O'Hehir; J Yendle; R J Hancock; Robert I Lechler
Contribution of T-cell receptor-contacting and peptide-binding residues of the class II molecule HLA-DR4 Dw10 to serologic and antigen-specific T-cell recognition.
Human immunology 1991;32(2):110-8.
1991: R E O'Hehir; H Yssel; S Verma; J E de Vries; H Spits; Jonathan R Lamb
Clonal analysis of differential lymphokine production in peptide and superantigen induced T cell anergy.
International immunology 1991;3(8):819-26.
1991: R E O'Hehir; Jonathan R Lamb
The cellular and molecular basis of the human T cell response to Dermatophagoides spp. (house dust mite).
Parasite immunology 1991;13(2):109-19.
1990: Jonathan R Lamb; D B Young
T cell recognition of stress proteins. A link between infectious and autoimmune disease.
Molecular biology & medicine 1990;7(4):311-21.
1990: Robyn E O'Hehir; B Mach; C Berte; R Greenlaw; J M Tiercy; V Bal; Robert I Lechler; J Trowsdale; Jonathan R Lamb
Direct evidence for a functional role of HLA-DRB1 and -DRB3 gene products in the recognition of Dermatophagoides spp. (house dust mite) by helper T lymphocytes.
International immunology 1990;2(9):885-92.
1989: S J Brett; Jonathan R Lamb; J H Cox; J B Rothbard; A Mehlert; Juraj Ivanyi
Differential pattern of T cell recognition of the 65-kDa mycobacterial antigen following immunization with the whole protein or peptides.
European journal of immunology 1989;19(7):1303-10.
1989: Jonathan R Lamb; A B Kay; Robyn E O'Hehir
HLA class II restriction specificity of Dermatophagoides spp. reactive T lymphocyte clones that support IgE synthesis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1989;19(4):389-93.
1989: Jonathan R Lamb; V Bal; J B Rothbard; A Mehlert; P Mendez-Samperio; D B Young
The mycobacterial GroEL stress protein: a common target of T-cell recognition in infection and autoimmunity.
Journal of autoimmunity 1989;2 Suppl():93-100.
1989: Robyn E O'Hehir; V Bal; D Quint; Redwan Moqbel; A Barry Kay; E D Zanders; Jonathan R Lamb
An in vitro model of allergen-dependent IgE synthesis by human B lymphocytes: comparison of the response of an atopic and a non-atopic individual to Dermatophagoides spp. (house dust mite).
Immunology 1989;66(4):499-504.
1989: Jonathan R Lamb; Raju Lathigra; J B Rothbard; D Sweetser; R A Young; Juraj Ivanyi; D B Young
Identification of mycobacterial antigens recognized by T lymphocytes.
Reviews of infectious diseases 1989;11 Suppl 2():S443-7.
1989: Giovanna Lombardi; S Sidhu; Jonathan R Lamb; J R Batchelor; Robert I Lechler
Endogenous peptides contribute to the ligand recognized by anti-DR1 human alloreactive T cells.
Transplantation proceedings 1989;21(1 Pt 1):142-4.
1989: Giovanna Lombardi; S Sidhu; Jonathan R Lamb; J R Batchelor; Robert I Lechler
Co-recognition of endogenous antigens with HLA-DR1 by alloreactive human T cell clones.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(3):753-9.
1989: J H Cox; Jonathan R Lamb; V Bal; G W Butcher; J C Howard; MJ Owen; Juraj Ivanyi
The phenotypic and molecular characterization of Nb2 lymphoma cells activated with IL-2 and human growth hormone.
Immunology 1989;66(1):83-9.
1989: J B Rothbard; R Busch; C M Hill; Jonathan R Lamb
Structural analysis of a peptide-HLA class II complex.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 1():431-44.
1989: J B Rothbard; R Busch; V Bal; J Trowsdale; R I Lechler; Jonathan R Lamb
Reversal of HLA restriction by a point mutation in an antigenic peptide.
International immunology 1989;1(5):487-95.
1989: J B Rothbard; R Busch; K Howland; V Bal; C Fenton; W R Taylor; Jonathan R Lamb
Structural analysis of a peptide--HLA class II complex: identification of critical interactions for its formation and recognition by T cell receptor.
International immunology 1989;1(5):479-86.
1989: Jonathan R Lamb; V Bal; P Mendez-Samperio; A Mehlert; A So; J Rothbard; S Jindal; R A Young; D B Young
Stress proteins may provide a link between the immune response to infection and autoimmunity.
International immunology 1989;1(2):191-6.
1988: P Maestrelli; Robyn E O'Hehir; Jonathan R Lamb; J J Tsai; O Cromwell; A Barry Kay
Antigen-induced neutrophil chemotactic factor from cloned human T lymphocytes.
Immunology 1988;65(4):605-9.
1988: M Larche; Jonathan R Lamb; Robyn E O'Hehir; N Imami-Shita; E D Zanders; D E Quint; Redwan Moqbel; Mary A Ritter
Functional evidence for a monoclonal antibody that binds to the human IL-4 receptor.
Immunology 1988;65(4):617-22.
1988: J H Cox; Juraj Ivanyi; D B Young; Jonathan R Lamb; A D Syred; M J Francis
Orientation of epitopes influences the immunogenicity of synthetic peptide dimers.
European journal of immunology 1988;18(12):2015-9.
1988: Robyn E O'Hehir; D D Eckels; Anthony J Frew; A Barry Kay; Jonathan R Lamb
MHC class II restriction specificity of cloned human T lymphocytes reactive with Dermatophagoides farinae (house dust mite).
Immunology 1988;64(4):627-31.
1988: Jonathan R Lamb; AD Rees; V Bal; H Ikeda; D Wilkinson; R R De Vries; J B Rothbard
Prediction and identification of an HLA-DR-restricted T cell determinant in the 19-kDa protein of Mycobacterium tuberculosis.
European journal of immunology 1988;18(6):973-6.
1988: F M Collins; Jonathan R Lamb; D B Young
Biological activity of protein antigens isolated from Mycobacterium tuberculosis culture filtrate.
Infection and immunity 1988;56(5):1260-6.
1988: M Larché; Jonathan R Lamb; Mary A Ritter
A novel T-lymphocyte molecule that may function in the induction of self-tolerance and MHC-restriction within the human thymic microenvironment.
Immunology 1988;64(1):101-5.
1988: J B Rothbard; Robert I Lechler; K Howland; V Bal; D D Eckels; R Sekaly; Eric Long; W R Taylor; Jonathan R Lamb
Structural model of HLA-DR1 restricted T cell antigen recognition.
Cell 1988;52(4):515-23.
1988: M Larche; Jonathan R Lamb; Mary A Ritter
p145-MR6: a novel T cell surface molecule with a role in tolerance to self.
Advances in experimental medicine and biology 1988;237():413-7.
1988: D B Young; A Mehlert; V Bal; P Mendez-Samperio; Juraj Ivanyi; Jonathan R Lamb
Stress proteins and the immune response to mycobacteria--antigens as virulence factors?
Antonie van Leeuwenhoek 1988;54(5):431-9.
1987: Robyn E O'Hehir; D B Young; A Barry Kay; Jonathan R Lamb
Cloned human T lymphocytes reactive with Dermatophagoides farinae (house dust mite): a comparison of T- and B-cell antigen recognition.
Immunology 1987;62(4):635-40.
1987: AD Rees; K Praputpittaya; A Scoging; N Dobson; Juraj Ivanyi; D Young; Jonathan R Lamb
T-cell activation by anti-idiotypic antibody: evidence for the internal image.
Immunology 1987;60(3):389-93.
1987: AD Rees; A Scoging; N Dobson; K Praputpittaya; D Young; Juraj Ivanyi; Jonathan R Lamb
T cell activation by anti-idiotypic antibody: mechanism of interaction with antigen-reactive T cells.
European journal of immunology 1987;17(2):197-201.