FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Robert Lamb

Research Profile

Anatomy

Chemicals & Drugs

Living Beings

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequences

Physiology

Co-author Network

Publications

TOP 3
Brett D Welch; Theodore S Jardetzky; Christopher A Kors; George P Leser; Yuanyuan Liu; Robert A Lamb
Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein.
Sayantan Bose; Theodore S Jardetzky; George P Leser; Brett D Welch; Aarohi Zokarkar; Robert A Lamb
Fusion activation by a headless parainfluenza virus 5 hemagglutinin-neuraminidase stalk suggests a modular mechanism for triggering.
Sayantan Bose; Theodore S Jardetzky; Christopher A Kors; Brett D Welch; Ping Yuan; Robert A Lamb
Structure and mutagenesis of the parainfluenza virus 5 hemagglutinin-neuraminidase stalk domain reveals a four-helix bundle and the role of the stalk in fusion promotion.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Robert Lamb (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Brett D Welch; Theodore S Jardetzky; Christopher A Kors; George P Leser; Yuanyuan Liu; Robert A Lamb
Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(41):16672-7.
2012: Sayantan Bose; Theodore S Jardetzky; George P Leser; Brett D Welch; Aarohi Zokarkar; Robert A Lamb
Fusion activation by a headless parainfluenza virus 5 hemagglutinin-neuraminidase stalk suggests a modular mechanism for triggering.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(39):E2625-34.
2011: Sayantan Bose; Theodore S Jardetzky; Christopher A Kors; Brett D Welch; Ping Yuan; Robert A Lamb
Structure and mutagenesis of the parainfluenza virus 5 hemagglutinin-neuraminidase stalk domain reveals a four-helix bundle and the role of the stalk in fusion promotion.
Journal of virology 2011;85(24):12855-66.
2010: Jessica G Robach; Robert A Lamb
Analysis of parainfluenza virus-5 hemagglutinin-neuraminidase protein mutants that are blocked in internalization and degradation.
Virology 2010;406(2):189-201.
2010: Dana Ravid; George P Leser; Robert A Lamb
A role for caveolin 1 in assembly and budding of the paramyxovirus parainfluenza virus 5.
Journal of virology 2010;84(19):9749-59.
2010: Rie Watanabe; Robert A Lamb
Influenza virus budding does not require a functional AAA+ ATPase, VPS4.
Virus research 2010;153(1):58-63.
2010: Jeremy S Rossman; Xianghong Jing; George P Leser; Robert A Lamb
Influenza virus M2 protein mediates ESCRT-independent membrane scission.
Cell 2010;142(6):902-13.
2010: Victoria Balannik; Vincenzo Carnevale; Giacomo Fiorin; Benjamin G Levine; Robert A Lamb; Michael L Klein; William F DeGrado; Lawrence H Pinto
Functional studies and modeling of pore-lining residue mutants of the influenza a virus M2 ion channel.
Biochemistry 2010;49(4):696-708.
2009: Victoria Balannik; Jun Wang; Yuki Ohigashi; Xianghong Jing; Emma Magavern; Robert A Lamb; William F DeGrado; Lawrence H Pinto
Design and pharmacological characterization of inhibitors of amantadine-resistant mutants of the M2 ion channel of influenza A virus.
Biochemistry 2009;48(50):11872-82.
2009: Yuki Ohigashi; Chunlong Ma; Xianghong Jing; Victoria Balannick; Lawrence H Pinto; Robert A Lamb
An amantadine-sensitive chimeric BM2 ion channel of influenza B virus has implications for the mechanism of drug inhibition.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(44):18775-9.
2009: Sarah A Connolly; George P Leser; Theodore S Jardetzky; Robert A Lamb
Bimolecular complementation of paramyxovirus fusion and hemagglutinin-neuraminidase proteins enhances fusion: implications for the mechanism of fusion triggering.
Journal of virology 2009;83(21):10857-68.
2009: Jeremy S Rossman; Robert A Lamb
Autophagy, apoptosis, and the influenza virus M2 protein.
Cell host & microbe 2009;6(4):299-300.
2009: Chunlong Ma; Alexei L Polishchuk; Yuki Ohigashi; Amanda L Stouffer; Arne Schön; Emma Magavern; Xianghong Jing; James D Lear; Ernesto Freire; Robert A Lamb; William F DeGrado; Lawrence H Pinto
Identification of the functional core of the influenza A virus A/M2 proton-selective ion channel.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(30):12283-8.
2009: Mei Lin Z Bissonnette; Jason E Donald; William F DeGrado; Theodore S Jardetzky; Robert A Lamb
Functional analysis of the transmembrane domain in paramyxovirus F protein-mediated membrane fusion.
Journal of molecular biology 2009;386(1):14-36.
2008: David Jackson; Robert A Lamb
The influenza A virus spliced messenger RNA M mRNA3 is not required for viral replication in tissue culture.
The Journal of general virology 2008;89(Pt 12):3097-101.
2008: Benjamin J Chen; George P Leser; David Jackson; Robert A Lamb
The influenza virus M2 protein cytoplasmic tail interacts with the M1 protein and influences virus assembly at the site of virus budding.
Journal of virology 2008;82(20):10059-70.
2008: Xianghong Jing; Chunlong Ma; Yuki Ohigashi; Fernando A Oliveira; Theodore S Jardetzky; Lawrence H Pinto; Robert A Lamb
Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(31):10967-72.
2008: Chunlong Ma; Cinque S Soto; Yuki Ohigashi; Albert Taylor; Vasilios Bournas; Brett Glawe; Maria K Udo; William F DeGrado; Robert A Lamb; Lawrence H Pinto
Identification of the pore-lining residues of the BM2 ion channel protein of influenza B virus.
The Journal of biological chemistry 2008;283(23):15921-31.
2008: David Jackson; Md Jaber Hossain; Danielle Hickman; Daniel Perez; Robert A Lamb
A new influenza virus virulence determinant: the NS1 protein four C-terminal residues modulate pathogenicity.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(11):4381-6.
2008: Benjamin J Chen; Robert A Lamb
Mechanisms for enveloped virus budding: can some viruses do without an ESCRT?
Virology 2008;372(2):221-32.
2007: Marija Backovic; George P Leser; Robert A Lamb; Richard Longnecker; Theodore S Jardetzky
Characterization of EBV gB indicates properties of both class I and class II viral fusion proteins.
Virology 2007;368(1):102-13.
2007: Rafael Vega; Clifton K-F Shen; daniel maspoch ; Jessica G Robach; Robert A Lamb; Chad A Mirkin
Monitoring single-cell infectivity from virus-particle nanoarrays fabricated by parallel dip-pen nanolithography.
Small (Weinheim an der Bergstrasse, Germany) 2007;3(9):1482-5.
2007: Robert A Lamb; Theodore S Jardetzky
Structural basis of viral invasion: lessons from paramyxovirus F.
Current opinion in structural biology 2007;17(4):427-36.
2007: Benjamin J Chen; George P Leser; Eiji Morita; Robert A Lamb
Influenza virus hemagglutinin and neuraminidase, but not the matrix protein, are required for assembly and budding of plasmid-derived virus-like particles.
Journal of virology 2007;81(13):7111-23.
2007: Stephen M Tompkins; Yuan Lin; George P Leser; Kari A Kramer; Debra L Haas; Elizabeth W Howerth; Jie Xu; Mary J. Kennett; Russell K Durbin; Joan E Durbin; Ralph A Tripp; Robert A Lamb; Biao He
Recombinant parainfluenza virus 5 (PIV5) expressing the influenza A virus hemagglutinin provides immunity in mice to influenza A virus challenge.
Virology 2007;362(1):139-50.
2007: Lawrence H Pinto; Robert A Lamb
Controlling influenza virus replication by inhibiting its proton channel.
Molecular bioSystems 2007;3(1):18-23.
2006: Sarah A Connolly; Robert A Lamb
Paramyxovirus fusion: real-time measurement of parainfluenza virus 5 virus-cell fusion.
Virology 2006;355(2):203-12.
2006: Sarah A Connolly; George P Leser; Hsien-Sheng Yin; Theodore S Jardetzky; Robert A Lamb
Refolding of a paramyxovirus F protein from prefusion to postfusion conformations observed by liposome binding and electron microscopy.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(47):17903-8.
2006: Rafael Vega; daniel maspoch ; Clifton K-F Shen; Joseph J Kakkassery; Benjamin J Chen; Robert A Lamb; Chad A Mirkin
Functional antibody arrays through metal ion-affinity templates.
Chembiochem : a European journal of chemical biology 2006;7(11):1653-7.
2006: Ben Hale; David Jackson; Yun-Hsiang Chen; Robert A Lamb; Richard E Randall
Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(38):14194-9.
2006: Lawrence H Pinto; Robert A Lamb
Influenza virus proton channels.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2006;5(6):629-32.
2006: Lawrence H Pinto; Robert A Lamb
The M2 proton channels of influenza A and B viruses.
The Journal of biological chemistry 2006;281(14):8997-9000.
2006: Mei Lin Z Bissonnette; Sarah A Connolly; Daniel F Young; Richard E Randall; Reay G Paterson; Robert A Lamb
Analysis of the pH requirement for membrane fusion of different isolates of the paramyxovirus parainfluenza virus 5.
Journal of virology 2006;80(6):3071-7.
2006: Hsien-Sheng Yin; Xiaolin Wen; Reay G Paterson; Robert A Lamb; Theodore S Jardetzky
Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation.
Nature 2006;439(7072):38-44.
2006: Robert A Lamb; Reay G Paterson; Theodore S Jardetzky
Paramyxovirus membrane fusion: lessons from the F and HN atomic structures.
Virology 2006;344(1):30-7.
2005: George P Leser; Robert A Lamb
Influenza virus assembly and budding in raft-derived microdomains: a quantitative analysis of the surface distribution of HA, NA and M2 proteins.
Virology 2005;342(2):215-27.
2005: Benjamin J Chen; Makoto Takeda; Robert A Lamb
Influenza virus hemagglutinin (H3 subtype) requires palmitoylation of its cytoplasmic tail for assembly: M1 proteins of two subtypes differ in their ability to support assembly.
Journal of virology 2005;79(21):13673-84.
2005: Hsien-Sheng Yin; Reay G Paterson; Xiaolin Wen; Robert A Lamb; Theodore S Jardetzky
Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(26):9288-93.
2005: Padmavati Venkataraman; Robert A Lamb; Lawrence H Pinto
Chemical rescue of histidine selectivity filter mutants of the M2 ion channel of influenza A virus.
The Journal of biological chemistry 2005;280(22):21463-72.
2005: Ping Yuan; Thomas B Thompson; Beth A Wurzburg; Reay G Paterson; Robert A Lamb; Theodore S Jardetzky
Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure (London, England : 1993) 2005;13(5):803-15.
2005: Anthony P Schmitt; George P Leser; Eiji Morita; Wesley I Sundquist; Robert A Lamb
Evidence for a new viral late-domain core sequence, FPIV, necessary for budding of a paramyxovirus.
Journal of virology 2005;79(5):2988-97.
2005: Anthony P Schmitt; Robert A Lamb
Influenza virus assembly and budding at the viral budozone.
Advances in virus research 2005;64():383-416.
2004: Charles J Russell; Theodore S Jardetzky; Robert A Lamb
Conserved glycine residues in the fusion peptide of the paramyxovirus fusion protein regulate activation of the native state.
Journal of virology 2004;78(24):13727-42.
2004: David L Waning; Charles J Russell; Theodore S Jardetzky; Robert A Lamb
Activation of a paramyxovirus fusion protein is modulated by inside-out signaling from the cytoplasmic tail.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(25):9217-22.
2004: Anthony P Schmitt; Robert A Lamb
Escaping from the cell: assembly and budding of negative-strand RNA viruses.
Current topics in microbiology and immunology 2004;283():145-96.
2003: Makoto Takeda; George P Leser; Charles J Russell; Robert A Lamb
Influenza virus hemagglutinin concentrates in lipid raft microdomains for efficient viral fusion.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):14610-7.
2003: Changlin Tian; Philip Fei Gao; Lawrence H Pinto; Robert A Lamb; Timothy A Cross
Initial structural and dynamic characterization of the M2 protein transmembrane and amphipathic helices in lipid bilayers.
Protein science : a publication of the Protein Society 2003;12(11):2597-605.
2003: Charles J Russell; Karen L Kantor; Theodore S Jardetzky; Robert A Lamb
A dual-functional paramyxovirus F protein regulatory switch segment: activation and membrane fusion.
The Journal of cell biology 2003;163(2):363-74.
2003: Jorgen A Mould; Reay G Paterson; Makoto Takeda; Yuki Ohigashi; Padmavati Venkataraman; Robert A Lamb; Lawrence H Pinto
Influenza B virus BM2 protein has ion channel activity that conducts protons across membranes.
Developmental cell 2003;5(1):175-84.
2003: Reay G Paterson; Makoto Takeda; Yuki Ohigashi; Lawrence H Pinto; Robert A Lamb
Influenza B virus BM2 protein is an oligomeric integral membrane protein expressed at the cell surface.
Virology 2003;306(1):7-17.
2003: Daniel F Young; L Andrejeva; A Livingstone; Stephen Goodbourn; Robert A Lamb; P L Collins; Richard M Elliott; Richard E Randall
Virus replication in engineered human cells that do not respond to interferons.
Journal of virology 2003;77(3):2174-81.
2002: Emma Poole; Biao He; Robert A Lamb; Richard E Randall; Stephen Goodbourn
The V proteins of simian virus 5 and other paramyxoviruses inhibit induction of interferon-beta.
Virology 2002;303(1):33-46.
2002: Biao He; Reay G Paterson; Nicola Stock; Joan E Durbin; Russell K Durbin; Stephen Goodbourn; Richard E Randall; Robert A Lamb
Recovery of paramyxovirus simian virus 5 with a V protein lacking the conserved cysteine-rich domain: the multifunctional V protein blocks both interferon-beta induction and interferon signaling.
Virology 2002;303(1):15-32.
2002: Yajun Tang; Florina Zaitseva; Robert A Lamb; Lawrence H Pinto
The gate of the influenza virus M2 proton channel is formed by a single tryptophan residue.
The Journal of biological chemistry 2002;277(42):39880-6.
2002: Changlin Tian; Kurt Tobler; Robert A Lamb; Lawrence H Pinto; Timothy A Cross
Expression and initial structural insights from solid-state NMR of the M2 proton channel from influenza A virus.
Biochemistry 2002;41(37):11294-300.
2002: David L Waning; Anthony P Schmitt; George P Leser; Robert A Lamb
Roles for the cytoplasmic tails of the fusion and hemagglutinin-neuraminidase proteins in budding of the paramyxovirus simian virus 5.
Journal of virology 2002;76(18):9284-97.
2002: Anthony P Schmitt; George P Leser; David L Waning; Robert A Lamb
Requirements for budding of paramyxovirus simian virus 5 virus-like particles.
Journal of virology 2002;76(8):3952-64.
2002: Makoto Takeda; Andrew Pekosz; Kevin Shuck; Lawrence H Pinto; Robert A Lamb
Influenza a virus M2 ion channel activity is essential for efficient replication in tissue culture.
Journal of virology 2002;76(3):1391-9.
2001: Charles J Russell; Theodore S Jardetzky; Robert A Lamb
Membrane fusion machines of paramyxoviruses: capture of intermediates of fusion.
The EMBO journal 2001;20(15):4024-34.
2001: Rebecca Ellis Dutch; Robert A Lamb
Deletion of the cytoplasmic tail of the fusion protein of the paramyxovirus simian virus 5 affects fusion pore enlargement.
Journal of virology 2001;75(11):5363-9.
2001: Biao He; GY Lin; Joan E Durbin; Russell K Durbin; Robert A Lamb
The SH integral membrane protein of the paramyxovirus simian virus 5 is required to block apoptosis in MDBK cells.
Journal of virology 2001;75(9):4068-79.
2001: Daniel F Young; N Chatziandreou; Biao He; Stephen Goodbourn; Robert A Lamb; Richard E Randall
Single amino acid substitution in the V protein of simian virus 5 differentiates its ability to block interferon signaling in human and murine cells.
Journal of virology 2001;75(7):3363-70.
2001: Rebecca Ellis Dutch; R N Hagglund; M A Nagel; Reay G Paterson; Robert A Lamb
Paramyxovirus fusion (F) protein: a conformational change on cleavage activation.
Virology 2001;281(1):138-50.
2000: Rebecca Ellis Dutch; Theodore S Jardetzky; Robert A Lamb
Virus membrane fusion proteins: biological machines that undergo a metamorphosis.
Bioscience reports 2000;20(6):597-612.
2000: Andrew Pekosz; Robert A Lamb
Identification of a membrane targeting and degradation signal in the p42 protein of influenza C virus.
Journal of virology 2000;74(22):10480-8.
2000: Jorgen A Mould; Jason Drury; Stephan Frings; U B Kaupp; Andrew Pekosz; Robert A Lamb; Lawrence H Pinto
Permeation and activation of the M2 ion channel of influenza A virus.
The Journal of biological chemistry 2000;275(40):31038-50.
2000: GY Lin; Robert A Lamb
The paramyxovirus simian virus 5 V protein slows progression of the cell cycle.
Journal of virology 2000;74(19):9152-66.
2000: Kevin Shuck; Robert A Lamb; Lawrence H Pinto
Analysis of the pore structure of the influenza A virus M(2) ion channel by the substituted-cysteine accessibility method.
Journal of virology 2000;74(17):7755-61.
2000: J Zhang; Andrew Pekosz; Robert A Lamb
Influenza virus assembly and lipid raft microdomains: a role for the cytoplasmic tails of the spike glycoproteins.
Journal of virology 2000;74(10):4634-44.
2000: Reay G Paterson; Charles J Russell; Robert A Lamb
Fusion protein of the paramyxovirus SV5: destabilizing and stabilizing mutants of fusion activation.
Virology 2000;270(1):17-30.
2000: J Zhang; George P Leser; Andrew Pekosz; Robert A Lamb
The cytoplasmic tails of the influenza virus spike glycoproteins are required for normal genome packaging.
Virology 2000;269(2):325-34.
2000: Jorgen A Mould; H C Li; C S Dudlak; James D Lear; Andrew Pekosz; Robert A Lamb; Lawrence H Pinto
Mechanism for proton conduction of the M(2) ion channel of influenza A virus.
The Journal of biological chemistry 2000;275(12):8592-9.
1999: K Tobler; M L Kelly; Lawrence H Pinto; Robert A Lamb
Effect of cytoplasmic tail truncations on the activity of the M(2) ion channel of influenza A virus.
Journal of virology 1999;73(12):9695-701.
1999: Andrew Pekosz; Robert A Lamb
Cell surface expression of biologically active influenza C virus HEF glycoprotein expressed from cDNA.
Journal of virology 1999;73(10):8808-12.
1999: Anthony P Schmitt; Biao He; Robert A Lamb
Involvement of the cytoplasmic domain of the hemagglutinin-neuraminidase protein in assembly of the paramyxovirus simian virus 5.
Journal of virology 1999;73(10):8703-12.
1999: George P Leser; K J Ector; D T Ng; M A Shaughnessy; Robert A Lamb
The signal for clathrin-mediated endocytosis of the paramyxovirus SV5 HN protein resides at the transmembrane domain-ectodomain boundary region.
Virology 1999;262(1):79-92.
1999: Andrew Pekosz; Biao He; Robert A Lamb
Reverse genetics of negative-strand RNA viruses: closing the circle.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(16):8804-6.
1999: Biao He; Robert A Lamb
Effect of inserting paramyxovirus simian virus 5 gene junctions at the HN/L gene junction: analysis of accumulation of mRNAs transcribed from rescued viable viruses.
Journal of virology 1999;73(8):6228-34.
1999: K A Baker; Rebecca Ellis Dutch; Robert A Lamb; Theodore S Jardetzky
Structural basis for paramyxovirus-mediated membrane fusion.
Molecular cell 1999;3(3):309-19.
1999: C S Gandhi; Kevin Shuck; James D Lear; GR Dieckmann; William F DeGrado; Robert A Lamb; Lawrence H Pinto
Cu(II) inhibition of the proton translocation machinery of the influenza A virus M2 protein.
The Journal of biological chemistry 1999;274(9):5474-82.
1999: C M Bauer; Lawrence H Pinto; Timothy A Cross; Robert A Lamb
The influenza virus M2 ion channel protein: probing the structure of the transmembrane domain in intact cells by using engineered disulfide cross-linking.
Virology 1999;254(1):196-209.
1999: Rebecca Ellis Dutch; George P Leser; Robert A Lamb
Paramyxovirus fusion protein: characterization of the core trimer, a rod-shaped complex with helices in anti-parallel orientation.
Virology 1999;254(1):147-59.
1999: Robert A Lamb; SB Joshi; Rebecca Ellis Dutch
The paramyxovirus fusion protein forms an extremely stable core trimer: structural parallels to influenza virus haemagglutinin and HIV-1 gp41.
Molecular membrane biology 1999;16(1):11-9.
1998: Andrew Pekosz; Robert A Lamb
Influenza C virus CM2 integral membrane glycoprotein is produced from a polypeptide precursor by cleavage of an internal signal sequence.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(22):13233-8.
1998: Biao He; George P Leser; Reay G Paterson; Robert A Lamb
The paramyxovirus SV5 small hydrophobic (SH) protein is not essential for virus growth in tissue culture cells.
Virology 1998;250(1):30-40.
1998: Rebecca Ellis Dutch; SB Joshi; Robert A Lamb
Membrane fusion promoted by increasing surface densities of the paramyxovirus F and HN proteins: comparison of fusion reactions mediated by simian virus 5 F, human parainfluenza virus type 3 F, and influenza virus HA.
Journal of virology 1998;72(10):7745-53.
1998: GY Lin; Reay G Paterson; C D Richardson; Robert A Lamb
The V protein of the paramyxovirus SV5 interacts with damage-specific DNA binding protein.
Virology 1998;249(1):189-200.
1998: SB Joshi; Rebecca Ellis Dutch; Robert A Lamb
A core trimer of the paramyxovirus fusion protein: parallels to influenza virus hemagglutinin and HIV-1 gp41.
Virology 1998;248(1):20-34.
1997: J Zhou; Rebecca Ellis Dutch; Robert A Lamb
Proper spacing between heptad repeat B and the transmembrane domain boundary of the paramyxovirus SV5 F protein is critical for biological activity.
Virology 1997;239(2):327-39.
1997: GY Lin; Reay G Paterson; Robert A Lamb
The RNA binding region of the paramyxovirus SV5 V and P proteins.
Virology 1997;238(2):460-9.
1997: S Bagai; Robert A Lamb
A glycine to alanine substitution in the paramyxovirus SV5 fusion peptide increases the initial rate of fusion.
Virology 1997;238(2):283-90.
1997: Andrew Pekosz; Robert A Lamb
The CM2 protein of influenza C virus is an oligomeric integral membrane glycoprotein structurally analogous to influenza A virus M2 and influenza B virus NB proteins.
Virology 1997;237(2):439-51.
1997: Biao He; Reay G Paterson; C D Ward; Robert A Lamb
Recovery of infectious SV5 from cloned DNA and expression of a foreign gene.
Virology 1997;237(2):249-60.
1997: Lawrence H Pinto; GR Dieckmann; C S Gandhi; C G Papworth; J Braman; M A Shaughnessy; James D Lear; Robert A Lamb; William F DeGrado
A functionally defined model for the M2 proton channel of influenza A virus suggests a mechanism for its ion selectivity.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(21):11301-6.
1997: Reay G Paterson; M L Johnson; Robert A Lamb
Paramyxovirus fusion (F) protein and hemagglutinin-neuraminidase (HN) protein interactions: intracellular retention of F and HN does not affect transport of the homotypic HN or F protein.
Virology 1997;237(1):1-9.
1997: D L Brassard; Robert A Lamb
Expression of influenza B virus hemagglutinin containing multibasic residue cleavage sites.
Virology 1997;236(2):234-48.
1997: T Sakaguchi; Q Tu; Lawrence H Pinto; Robert A Lamb
The active oligomeric state of the minimalistic influenza virus M2 ion channel is a tetramer.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(10):5000-5.
1997: Hong Jin; George P Leser; J Zhang; Robert A Lamb
Influenza virus hemagglutinin and neuraminidase cytoplasmic tails control particle shape.
The EMBO journal 1997;16(6):1236-47.
1997: Robert A Lamb; Lawrence H Pinto
Do Vpu and Vpr of human immunodeficiency virus type 1 and NB of influenza B virus have ion channel activities in the viral life cycles?
Virology 1997;229(1):1-11.
1996: J Zhang; Robert A Lamb
Characterization of the membrane association of the influenza virus matrix protein in living cells.
Virology 1996;225(2):255-66.
1996: S Bagai; Robert A Lamb
Truncation of the COOH-terminal region of the paramyxovirus SV5 fusion protein leads to hemifusion but not complete fusion.
The Journal of cell biology 1996;135(1):73-84.
1996: Q Tu; Lawrence H Pinto; Guangxiang Luo; M A Shaughnessy; D Mullaney; S Kurtz; Mark Krystal; Robert A Lamb
Characterization of inhibition of M2 ion channel activity by BL-1743, an inhibitor of influenza A virus.
Journal of virology 1996;70(7):4246-52.
1996: D L Brassard; George P Leser; Robert A Lamb
Influenza B virus NB glycoprotein is a component of the virion.
Virology 1996;220(2):350-60.
1996: T Sakaguchi; George P Leser; Robert A Lamb
The ion channel activity of the influenza virus M2 protein affects transport through the Golgi apparatus.
The Journal of cell biology 1996;133(4):733-47.
1996: K Shimbo; D L Brassard; Robert A Lamb; Lawrence H Pinto
Ion selectivity and activation of the M2 ion channel of influenza virus.
Biophysical journal 1996;70(3):1335-46.
1996: Hong Jin; K Subbarao; S Bagai; George P Leser; Brian Murphy; Robert A Lamb
Palmitylation of the influenza virus hemagglutinin (H3) is not essential for virus assembly or infectivity.
Journal of virology 1996;70(3):1406-14.
1996: George P Leser; K J Ector; Robert A Lamb
The paramyxovirus simian virus 5 hemagglutinin-neuraminidase glycoprotein, but not the fusion glycoprotein, is internalized via coated pits and enters the endocytic pathway.
Molecular biology of the cell 1996;7(1):155-72.
1995: K Shimbo; D L Brassard; Robert A Lamb; Lawrence H Pinto
Viral and cellular small integral membrane proteins can modify ion channels endogenous to Xenopus oocytes.
Biophysical journal 1995;69(5):1819-29.
1995: S Bagai; Robert A Lamb
Quantitative measurement of paramyxovirus fusion: differences in requirements of glycoproteins between simian virus 5 and human parainfluenza virus 3 or Newcastle disease virus.
Journal of virology 1995;69(11):6712-9.
1995: C Wang; Robert A Lamb; Lawrence H Pinto
Activation of the M2 ion channel of influenza virus: a role for the transmembrane domain histidine residue.
Biophysical journal 1995;69(4):1363-71.
1995: S Bagai; Robert A Lamb
Individual roles of N-linked oligosaccharide chains in intracellular transport of the paramyxovirus SV5 fusion protein.
Virology 1995;209(1):250-6.
1995: C D Ward; Reay G Paterson; Robert A Lamb
Mutants of the paramyxovirus SV5 fusion protein: regulated and extensive syncytium formation.
Virology 1995;209(1):242-9.
1995: Reay G Paterson; George P Leser; M A Shaughnessy; Robert A Lamb
The paramyxovirus SV5 V protein binds two atoms of zinc and is a structural component of virions.
Virology 1995;208(1):121-31.
1995: L J Holsinger; M A Shaughnessy; A Micko; Lawrence H Pinto; Robert A Lamb
Analysis of the posttranslational modifications of the influenza virus M2 protein.
Journal of virology 1995;69(2):1219-25.
1994: Hong Jin; George P Leser; Robert A Lamb
The influenza virus hemagglutinin cytoplasmic tail is not essential for virus assembly or infectivity.
The EMBO journal 1994;13(22):5504-15.
1994: C Wang; Robert A Lamb; Lawrence H Pinto
Direct measurement of the influenza A virus M2 protein ion channel activity in mammalian cells.
Virology 1994;205(1):133-40.
1994: Magdalena T Tosteson; Lawrence H Pinto; L J Holsinger; Robert A Lamb
Reconstitution of the influenza virus M2 ion channel in lipid bilayers.
The Journal of membrane biology 1994;142(1):117-26.
1994: K Takeuchi; M A Shaughnessy; Robert A Lamb
Influenza virus M2 protein ion channel activity is not required to maintain the equine-1 hemagglutinin in its native form in infected cells.
Virology 1994;202(2):1007-11.
1994: L J Holsinger; D Nichani; Lawrence H Pinto; Robert A Lamb
Influenza A virus M2 ion channel protein: a structure-function analysis.
Journal of virology 1994;68(3):1551-63.
1994: R Russell; Reay G Paterson; Robert A Lamb
Studies with cross-linking reagents on the oligomeric form of the paramyxovirus fusion protein.
Virology 1994;199(1):160-8.
1994: K Takeuchi; Robert A Lamb
Influenza virus M2 protein ion channel activity stabilizes the native form of fowl plague virus hemagglutinin during intracellular transport.
Journal of virology 1994;68(2):911-9.
1993: Robert A Lamb
Paramyxovirus fusion: a hypothesis for changes.
Virology 1993;197(1):1-11.
1993: G D Parks; Robert A Lamb
Role of NH2-terminal positively charged residues in establishing membrane protein topology.
The Journal of biological chemistry 1993;268(25):19101-9.
1993: C Wang; K Takeuchi; Lawrence H Pinto; Robert A Lamb
Ion channel activity of influenza A virus M2 protein: characterization of the amantadine block.
Journal of virology 1993;67(9):5585-94.
1992: Curt M Horvath; Reay G Paterson; M A Shaughnessy; R Wood; Robert A Lamb
Biological activity of paramyxovirus fusion proteins: factors influencing formation of syncytia.
Journal of virology 1992;66(7):4564-9.
1992: Lawrence H Pinto; L J Holsinger; Robert A Lamb
Influenza virus M2 protein has ion channel activity.
Cell 1992;69(3):517-28.
1992: Curt M Horvath; Robert A Lamb
Studies on the fusion peptide of a paramyxovirus fusion glycoprotein: roles of conserved residues in cell fusion.
Journal of virology 1992;66(4):2443-55.
1992: G D Parks; C D Ward; Robert A Lamb
Molecular cloning of the NP and L genes of simian virus 5: identification of highly conserved domains in paramyxovirus NP and L proteins.
Virus research 1992;22(3):259-79.
1992: D T Ng; S S Watowich; Robert A Lamb
Analysis in vivo of GRP78-BiP/substrate interactions and their role in induction of the GRP78-BiP gene.
Molecular biology of the cell 1992;3(2):143-55.
1992: D A Simpson; Robert A Lamb
Alterations to influenza virus hemagglutinin cytoplasmic tail modulate virus infectivity.
Journal of virology 1992;66(2):790-803.
1991: D A Simpson; Robert A Lamb
Influenza virus ts61S hemagglutinin is significantly defective in polypeptide folding and intracellular transport at the permissive temperature.
Virology 1991;185(1):477-83.
1991: H Sheshberadaran; Robert A Lamb
Simian virus 5 membrane protein maturation: expression in virus-infected cells and from a eukaryotic vector.
Virology 1991;183(2):803-9.
1991: L J Holsinger; Robert A Lamb
Influenza virus M2 integral membrane protein is a homotetramer stabilized by formation of disulfide bonds.
Virology 1991;183(1):32-43.
1991: S S Watowich; Richard I Morimoto; Robert A Lamb
Flux of the paramyxovirus hemagglutinin-neuraminidase glycoprotein through the endoplasmic reticulum activates transcription of the GRP78-BiP gene.
Journal of virology 1991;65(7):3590-7.
1991: G D Parks; Robert A Lamb
Topology of eukaryotic type II membrane proteins: importance of N-terminal positively charged residues flanking the hydrophobic domain.
Cell 1991;64(4):777-87.
1990: G D Parks; Robert A Lamb
Folding and oligomerization properties of a soluble and secreted form of the paramyxovirus hemagglutinin-neuraminidase glycoprotein.
Virology 1990;178(2):498-508.
1990: Reay G Paterson; Robert A Lamb
RNA editing by G-nucleotide insertion in mumps virus P-gene mRNA transcripts.
Journal of virology 1990;64(9):4137-45.
1990: G D Parks; Robert A Lamb
Defective assembly and intracellular transport of mutant paramyxovirus hemagglutinin-neuraminidase proteins containing altered cytoplasmic domains.
Journal of virology 1990;64(8):3605-16.
1990: Curt M Horvath; M A Williams; Robert A Lamb
Eukaryotic coupled translation of tandem cistrons: identification of the influenza B virus BM2 polypeptide.
The EMBO journal 1990;9(8):2639-47.
1990: H Sheshberadaran; Robert A Lamb
Sequence characterization of the membrane protein gene of paramyxovirus simian virus 5.
Virology 1990;176(1):234-43.
1990: D T Ng; S W Hiebert; Robert A Lamb
Different roles of individual N-linked oligosaccharide chains in folding, assembly, and transport of the simian virus 5 hemagglutinin-neuraminidase.
Molecular and cellular biology 1990;10(5):1989-2001.
1990: Reay G Paterson; Robert A Lamb
Conversion of a class II integral membrane protein into a soluble and efficiently secreted protein: multiple intracellular and extracellular oligomeric and conformational forms.
The Journal of cell biology 1990;110(4):999-1011.
1989: D T Ng; R E Randall; Robert A Lamb
Intracellular maturation and transport of the SV5 type II glycoprotein hemagglutinin-neuraminidase: specific and transient association with GRP78-BiP in the endoplasmic reticulum and extensive internalization from the cell surface.
The Journal of cell biology 1989;109(6 Pt 2):3273-89.
1989: G D Parks; J D Hull; Robert A Lamb
Transposition of domains between the M2 and HN viral membrane proteins results in polypeptides which can adopt more than one membrane orientation.
The Journal of cell biology 1989;109(5):2023-32.
1989: S L Zebedee; Robert A Lamb
Nucleotide sequences of influenza A virus RNA segment 7: a comparison of five isolates.
Nucleic acids research 1989;17(7):2870.
1989: Reay G Paterson; M A Shaughnessy; Robert A Lamb
Analysis of the relationship between cleavability of a paramyxovirus fusion protein and length of the connecting peptide.
Journal of virology 1989;63(3):1293-301.
1989: S L Zebedee; Robert A Lamb
Growth restriction of influenza A virus by M2 protein antibody is genetically linked to the M1 protein.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(3):1061-5.
1989: M A Williams; Robert A Lamb
Effect of mutations and deletions in a bicistronic mRNA on the synthesis of influenza B virus NB and NA glycoproteins.
Journal of virology 1989;63(1):28-35.
1988: Sheila M Thomas; Robert A Lamb; Reay G Paterson
Two mRNAs that differ by two nontemplated nucleotides encode the amino coterminal proteins P and V of the paramyxovirus SV5.
Cell 1988;54(6):891-902.
1988: S W Hiebert; Robert A Lamb
Cell surface expression of glycosylated, nonglycosylated, and truncated forms of a cytoplasmic protein pyruvate kinase.
The Journal of cell biology 1988;107(3):865-76.
1988: S L Zebedee; Robert A Lamb
Influenza A virus M2 protein: monoclonal antibody restriction of virus growth and detection of M2 in virions.
Journal of virology 1988;62(8):2762-72.
1988: S W Hiebert; C D Richardson; Robert A Lamb
Cell surface expression and orientation in membranes of the 44-amino-acid SH protein of simian virus 5.
Journal of virology 1988;62(7):2347-57.
1988: J D Hull; R Gilmore; Robert A Lamb
Integration of a small integral membrane protein, M2, of influenza virus into the endoplasmic reticulum: analysis of the internal signal-anchor domain of a protein with an ectoplasmic NH2 terminus.
The Journal of cell biology 1988;106(5):1489-98.
1988: M A Williams; Robert A Lamb
Polylactosaminoglycan modification of a small integral membrane glycoprotein, influenza B virus NB.
Molecular and cellular biology 1988;8(3):1186-96.