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Gérard Lambeau

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Chemicals & Drugs

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Mouse

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Cornelia Dähnrich; Vincent Esnault; Julia M Hofstra; Elion Hoxha; Lars Komorowski; Gérard Lambeau; Christian Probst; Barbara Seitz-Polski; Rolf A Stahl; Winfried Stöcker; Jack F Wetzels; Wolfgang Schlumberger
Development of a standardized ELISA for the determination of autoantibodies against human M-type phospholipase A2 receptor in primary membranous nephropathy.
Hafid Ait-Oufella; Christoph J Binder; Olivier Blanc-Brude; Christelle Coatrieux; Christophe A Girard; Olivier Herbin; Jeremie Joffre; Sonia Karabina; Charlotte Lahoute; Gérard Lambeau; Ludivine Laurans; Xavier Loyer; Makoto Murakami; Christine Payré; Bhama Ramkhelawon; Alain Tedgui; Kei Yamamoto; Ziad Mallat
Group X secreted phospholipase A2 limits the development of atherosclerosis in LDL receptor-null mice.
Ingrid Gomez; Gérard Lambeau; Julien Le Dall; Guy Leséche; Dan Longrois; Liliane Louedec; Chabha Benyahia; Christine Payré; Xavier Norel
Absence of inflammatory conditions in human varicose saphenous veins.

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2013: Cornelia Dähnrich; Vincent Esnault; Julia M Hofstra; Elion Hoxha; Lars Komorowski; Gérard Lambeau; Christian Probst; Barbara Seitz-Polski; Rolf A Stahl; Winfried Stöcker; Jack F Wetzels; Wolfgang Schlumberger
Development of a standardized ELISA for the determination of autoantibodies against human M-type phospholipase A2 receptor in primary membranous nephropathy.
Clinica chimica acta; international journal of clinical chemistry 2013;421():213-8.
2013: Hafid Ait-Oufella; Christoph J Binder; Olivier Blanc-Brude; Christelle Coatrieux; Christophe A Girard; Olivier Herbin; Jeremie Joffre; Sonia Karabina; Charlotte Lahoute; Gérard Lambeau; Ludivine Laurans; Xavier Loyer; Makoto Murakami; Christine Payré; Bhama Ramkhelawon; Alain Tedgui; Kei Yamamoto; Ziad Mallat
Group X secreted phospholipase A2 limits the development of atherosclerosis in LDL receptor-null mice.
Arteriosclerosis, thrombosis, and vascular biology 2013;33(3):466-73.
2013: Ingrid Gomez; Gérard Lambeau; Julien Le Dall; Guy Leséche; Dan Longrois; Liliane Louedec; Chabha Benyahia; Christine Payré; Xavier Norel
Absence of inflammatory conditions in human varicose saphenous veins.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2013;62(3):299-308.
2013: Makoto Murakami; Gérard Lambeau
Emerging roles of secreted phospholipase A(2) enzymes: an update.
Biochimie 2013;95(1):43-50.
2013: Vanessa Point; Anaïs Bénarouche; Frédéric Carrière; Ikram Jemel; Gérard Lambeau; Goetz Parsiegla; JF Cavalier
Effects of the propeptide of group X secreted phospholipase A(2) on substrate specificity and interfacial activity on phospholipid monolayers.
Biochimie 2013;95(1):51-8.
2012: Rajai Atout; Martine Carreras; Sandra Dollet; Sonia-Athina Karabina; Gérard Lambeau; Vincent Lotteau; Ewa Ninio; Christine Payré; Patrice André; Laure Perrin-Cocon
Human group X secreted phospholipase A2 induces dendritic cell maturation through lipoprotein-dependent and -independent mechanisms.
Atherosclerosis 2012;222(2):367-74.
2012: Christophe Arnoult; jessica Escoffier; Sylviane Hennebicq; Gérard Lambeau; Léa Munch; Virginie Pierre; Pierre Ray
[Do phospholipases, key enzymes in sperm physiology, represent therapeutic challenges?].
Médecine sciences : M/S 2012;28(5):512-8.
2012: Erika B Villanueva; Gérard Lambeau; Jonathan P Little; Andis Klegeris
Secreted phospholipase A(2) group IIA is a neurotoxin released by stimulated human glial cells.
Molecular and cellular neurosciences 2012;49(4):430-8.
2011: Ikram Jemel; Rob C Oslund; Christine Payré; Sabine Scarzello; Khaoula Chargui; Anne-Sophie Dabert-Gay; Dominique Douguet; Michael H Gelb; Hiromi Ii; Gérard Lambeau
Group X secreted phospholipase A2 proenzyme is matured by a furin-like proprotein convertase and releases arachidonic acid inside of human HEK293 cells.
The Journal of biological chemistry 2011;286(42):36509-21.
2011: Norbert Degousee; Gerd Geisslinger; Michael H Gelb; David M Hwang; Armand Keating; David J Kelvin; Gérard Lambeau; Thomas F Lindsay; Christine Payré; Carlo Angioni; Jonathan P Arm; James Bollinger; Ali Danesh; Helmut Schmidt; Eva Stefanski; Xing-Hua Wang; Barry B Rubin
Group V phospholipase A2 in bone marrow-derived myeloid cells and bronchial epithelial cells promotes bacterial clearance after Escherichia coli pneumonia.
The Journal of biological chemistry 2011;286(41):35650-62.
2011: jessica Escoffier; Ikram Jemel; Gérard Lambeau; Léa Munch; Virginie J Pierre; Pierre F Ray; Zied Boudhraa; Michel De Waard; Christophe Arnoult
Group X secreted phospholipase A₂ specifically decreases sperm motility in mice.
Journal of cellular physiology 2011;226(10):2601-9.
2010: Ziad Mallat; Gérard Lambeau; Alain Tedgui
Lipoprotein-associated and secreted phospholipases A₂ in cardiovascular disease: roles as biological effectors and biomarkers.
Circulation 2010;122(21):2183-200.
2010: Sarah Gora; Maouche Seraya; Rajai Atout; Kristell Wanherdrick; Gérard Lambeau; François Cambien; Ewa Ninio; Sonia-Athina Karabina
Phospholipolyzed LDL induces an inflammatory response in endothelial cells through endoplasmic reticulum stress signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(9):3284-97.
2010: Caroline Subra; David Grand; Karine Laulagnier; Alexandre Stella; Gérard Lambeau; Michael Paillasse; Philippe De Medina; Bernard Monsarrat; Bertrand PERRET; Sandrine Silvente-Poirot; Marc Poirot; Michel Record
Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins.
Journal of lipid research 2010;51(8):2105-20.
2010: jessica Escoffier; Morgane Couvet; Harold de Pomyers; Pierre F Ray; Michel Sève; Gérard Lambeau; Michel De Waard; Christophe Arnoult
Snake venoms as a source of compounds modulating sperm physiology: Secreted phospholipases A2 from Oxyuranus scutellatus scutellatus impact sperm motility, acrosome reaction and in vitro fertilization in mice.
Biochimie 2010;92(7):826-36.
2010: Makoto Murakami; Yoshitaka Taketomi; Christophe Girard; Kei Yamamoto; Gérard Lambeau
Emerging roles of secreted phospholipase A2 enzymes: Lessons from transgenic and knockout mice.
Biochimie 2010;92(6):561-82.
2010: Mathieu Schué; Damien Maurin; Rabeb Dhouib; Jean-Claude Bakala N'Goma; Vincent Delorme; Gérard Lambeau; Frédéric Carrière; Stéphane Canaan
Two cutinase-like proteins secreted by Mycobacterium tuberculosis show very different lipolytic activities reflecting their physiological function.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(6):1893-903.
2010: Eric Boilard; Ying Lai; Katherine Larabee; Barbara Balestrieri; Farideh Ghomashchi; Daisuke Fujioka; Reuben Gobezie; Jonathan S Coblyn; Michael E Weinblatt; Elena M Massarotti; Thomas S Thornhill; Maziar Divangahi; Heinz Remold; Gérard Lambeau; Michael H Gelb; Jonathan P Arm; David M Lee
A novel anti-inflammatory role for secretory phospholipase A2 in immune complex-mediated arthritis.
EMBO molecular medicine 2010;2(5):172-87.
2010: jessica Escoffier; Ikram Jemel; Akemi Tanemoto; Yoshitaka Taketomi; Christine Payre; Christelle Coatrieux; Hiroyasu Sato; Kei Yamamoto; Seiko Masuda; Karin Pernet-Gallay; Virginie Pierre; Shuntaro Hara; Makoto Murakami; Michel De Waard; Gérard Lambeau; Christophe Arnoult
Group X phospholipase A2 is released during sperm acrosome reaction and controls fertility outcome in mice.
The Journal of clinical investigation 2010;120(5):1415-28.
2009: Fanny Surrel; Ikram Jemel; Eric Boilard; James G Bollinger; Christine Payré; Carine M Mounier; Kati A Talvinen; Veli J O Laine; Timo J Nevalainen; Michael H Gelb; Gérard Lambeau
Group X phospholipase A2 stimulates the proliferation of colon cancer cells by producing various lipid mediators.
Molecular pharmacology 2009;76(4):778-90.
2009: Laurence H Beck; Ramon Bonegio; Gérard Lambeau; David M Beck; David W Powell; Timothy D Cummins; Klein Jon; David J Salant
M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy.
The New England journal of medicine 2009;361(1):11-21.
2009: Sarah Gora; Claire Perret; Ikram Jemel; Viviane Nicaud; Gérard Lambeau; François Cambien; Ewa Ninio; Stefan Blankenberg; Laurence Tiret; Sonia-Athina Karabina
Molecular and functional characterization of polymorphisms in the secreted phospholipase A2 group X gene: relevance to coronary artery disease.
Journal of molecular medicine (Berlin, Germany) 2009;87(7):723-33.
2009: Arnaud Augert; Christine Payré; Yvan de Launoit; Jesus Gil; Gérard Lambeau; David Bernard
The M-type receptor PLA2R regulates senescence through the p53 pathway.
EMBO reports 2009;10(3):271-7.
2009: Giorgio Giannattasio; Ying Lai; Francescopaolo Granata; Carine M Mounier; Laxman Nallan; Rob Oslund; Christina C Leslie; Gianni Marone; Gérard Lambeau; Michael H Gelb; Massimo Triggiani
Expression of phospholipases A2 in primary human lung macrophages: role of cytosolic phospholipase A2-alpha in arachidonic acid release and platelet activating factor synthesis.
Biochimica et biophysica acta 2009;1791(2):92-102.
2009: Gilles Guichard; Gersande Léna; Joel Boeglin; Pascal Muller; Eric Boilard; Gérard Lambeau; Didier Rognan; Claude Didierjean
1,3,5-Triazepan-2,6-diones as conformationally constrained dipeptide mimetics. In silico guided identification of sPLA2 inhibitors.
Advances in experimental medicine and biology 2009;611():201-2.
2008: Carine M Mounier; D Wendum; Emily J Greenspan; J-F Fléjou; D W Rosenberg; Gérard Lambeau
Distinct expression pattern of the full set of secreted phospholipases A2 in human colorectal adenocarcinomas: sPLA2-III as a biomarker candidate.
British journal of cancer 2008;98(3):587-95.
2008: Gérard Lambeau; Michael H Gelb
Biochemistry and physiology of mammalian secreted phospholipases A2.
Annual review of biochemistry 2008;77():495-520.
2008: Sophie Limou; Cédric Coulonges; Mario Foglio; Simon Heath; Gora Diop; Sigrid Leclerc; Thomas Hirtzig; Jean-Louis Spadoni; Amu Therwath; Gérard Lambeau; Ivo Gut; Jean-François Zagury
Exploration of associations between phospholipase A2 gene family polymorphisms and AIDS progression using the SNPlex method.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2008;62(1):31-40.
2007: Julie Pannequin; Nathalie Delaunay; Michael Buchert; Fanny Surrel; Jean-François Bourgaux; Joanne Ryan; Stéphanie Boireau; Jessica Coelho; André Pélegrin; Pomila Singh; Arthur Shulkes; Mildred Yim; Graham S Baldwin; Christine Pignodel; Gérard Lambeau; Philippe Jay; Dominique Joubert; Frédéric Hollande
Beta-catenin/Tcf-4 inhibition after progastrin targeting reduces growth and drives differentiation of intestinal tumors.
Gastroenterology 2007;133(5):1554-68.
2007: Mohamed Touaibia; Atimé Djimdé; Fei Cao; Eric Boilard; Laboratoire Biochimie et Genie Enzymatique des Lipases; Gérard Lambeau; Catherine Redeuilh; Aazdine Lamouri; France Massicot; François Chau; Chang-Zhi Dong; Françoise Heymans
Inhibition of secreted phospholipase A2. 4-glycerol derivatives of 4,5-dihydro-3-(4-tetradecyloxybenzyl)-1,2,4-4H-oxadiazol-5-one with broad activities.
Journal of medicinal chemistry 2007;50(7):1618-26.
2007: Thomas Maurin; David Fenard; Gérard Lambeau; Alain Doglio
An envelope-determined endocytic route of viral entry allows HIV-1 to escape from secreted phospholipase A2 entry blockade.
Journal of molecular biology 2007;367(3):702-14.
2007: Morgane Rouault; Catherine Le Calvez; Eric Boilard; Fanny Surrel; Alan Singer; Farideh Ghomashchi; Laboratoire Biochimie et Genie Enzymatique des Lipases; Sabine Scarzello; James Bollinger; Michael H Gelb; Gérard Lambeau
Recombinant production and properties of binding of the full set of mouse secreted phospholipases A2 to the mouse M-type receptor.
Biochemistry 2007;46(6):1647-62.
2006: Sonia-Athina Karabina; Isabelle Brochériou; Gilles Le Naour; Monique Agrapart; Hervé Durand; Michael Gelb; Gérard Lambeau; Ewa Ninio
Atherogenic properties of LDL particles modified by human group X secreted phospholipase A2 on human endothelial cell function.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(14):2547-9.
2006: Pascal Muller; Gersande Lena; Eric Boilard; Laboratoire Biochimie et Genie Enzymatique des Lipases; Gérard Lambeau; Gilles Guichard; Didier Rognan
In silico-guided target identification of a scaffold-focused library: 1,3,5-triazepan-2,6-diones as novel phospholipase A2 inhibitors.
Journal of medicinal chemistry 2006;49(23):6768-78.
2006: Eric Boilard; Morgane Rouault; Fanny Surrel; Catherine Le Calvez; Laboratoire Biochimie et Genie Enzymatique des Lipases; Alan Singer; Michael H Gelb; Gérard Lambeau
Secreted phospholipase A2 inhibitors are also potent blockers of binding to the M-type receptor.
Biochemistry 2006;45(44):13203-18.
2006: S Beck; G Beck; Tammo Ostendorf; J Floege; Gérard Lambeau; T Nevalainen; Heinfried Radeke; Silvia Gurrieri; Ulrike Haas; B Thorwart; Josef Pfeilschifter; Marietta Kaszkin
Upregulation of group IB secreted phospholipase A(2) and its M-type receptor in rat ANTI-THY-1 glomerulonephritis.
Kidney international 2006;70(7):1251-60.
2006: Sarah Gora; Gérard Lambeau; James G Bollinger; Michael Gelb; Ewa Ninio; Sonia-Athina Karabina
The proinflammatory mediator Platelet Activating Factor is an effective substrate for human group X secreted phospholipase A2.
Biochimica et biophysica acta 2006;1761(9):1093-9.
2006: Leena I Eerola; Fanny Surrel; Timo J Nevalainen; Michael H Gelb; Gérard Lambeau; Jukka Laine
Analysis of expression of secreted phospholipases A2 in mouse tissues at protein and mRNA levels.
Biochimica et biophysica acta 2006;1761(7):745-56.
2006: Morgane Rouault; Lachlan D Rash; pierre escoubas; Eric Boilard; James Bollinger; Bruno Lomonte; Thomas Maurin; Carole Guillaume; Stéphane Canaan; Christiane Deregnaucourt; Joseph Schrével; Alain Doglio; José María Gutiérrez; Michel Lazdunski; Michael H Gelb; Gérard Lambeau
Neurotoxicity and other pharmacological activities of the snake venom phospholipase A2 OS2: the N-terminal region is more important than enzymatic activity.
Biochemistry 2006;45(18):5800-16.
2006: Miguel SALINAS; Lachlan D Rash; Anne Baron; Gérard Lambeau; pierre escoubas; Michel Lazdunski
The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1a.
The Journal of physiology 2006;570(Pt 2):339-54.
2005: Alejandro Piris-Gimenez; Miguel Paya; Gérard Lambeau; Michel Chignard; Michèle Mock; Lhousseine Touqui; Pierre L Goossens
In vivo protective role of human group IIa phospholipase A2 against experimental anthrax.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(10):6786-91.
2005: Timo J Nevalainen; Leena I Eerola; Erkki Rintala; Jukka Laine; Gérard Lambeau; Michael H Gelb
Time-resolved fluoroimmunoassays of the complete set of secreted phospholipases A2 in human serum.
Biochimica et biophysica acta 2005;1733(2-3):210-23.
2005: Shee-Mei Lok; Rong Gao; Morgane Rouault; Gérard Lambeau; Ponnampalam Gopalakrishnakone; Kunchithapadam Swaminathan
Structure and function comparison of Micropechis ikaheka snake venom phospholipase A2 isoenzymes.
The FEBS journal 2005;272(5):1211-20.
2005: Ulrike Haas; Maurizio Podda; Martin Behne; Silvia Gurrieri; Angel Alonso; Gerhard Fürstenberger; Josef Pfeilschifter; Gérard Lambeau; Michael H Gelb; Marietta Kaszkin
Characterization and differentiation-dependent regulation of secreted phospholipases A in human keratinocytes and in healthy and psoriatic human skin.
The Journal of investigative dermatology 2005;124(1):204-11.
2005: Francescopaolo Granata; Angelica Petraroli; Eric Boilard; Laboratoire Biochimie et Genie Enzymatique des Lipases; James Bollinger; Luigi Del Vecchio; Michael H Gelb; Gérard Lambeau; Gianni Marone; Massimo Triggiani
Activation of cytokine production by secreted phospholipase A2 in human lung macrophages expressing the M-type receptor.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(1):464-74.
2004: Seiko Masuda; Makoto Murakami; Shigeko Matsumoto; Naomi Eguchi; Yoshihiro Urade; Gérard Lambeau; Michael H Gelb; Yukio Ishikawa; Toshiharu Ishii; Ichiro Kudo
Localization of various secretory phospholipase A2 enzymes in male reproductive organs.
Biochimica et biophysica acta 2004;1686(1-2):61-76.
2004: Laure Perrin-Cocon; Sophie Agaugué; Frédéric Coutant; Aurélie Masurel; Laboratoire Biochimie et Genie Enzymatique des Lipases; Gérard Lambeau; Patrice André; Vincent Lotteau
Secretory phospholipase A2 induces dendritic cell maturation.
European journal of immunology 2004;34(8):2293-302.
2003: Morgane Rouault; James G Bollinger; Michel Lazdunski; Michael H Gelb; Gérard Lambeau
Novel mammalian group XII secreted phospholipase A2 lacking enzymatic activity.
Biochemistry 2003;42(39):11494-503.
2003: Sabine Beck; Gérard Lambeau; Kristen Scholz-Pedretti; Michael H Gelb; Marcel J W Janssen; Suzanne H Edwards; David C Wilton; Josef Pfeilschifter; Marietta Kaszkin
Potentiation of tumor necrosis factor alpha-induced secreted phospholipase A2 (sPLA2)-IIA expression in mesangial cells by an autocrine loop involving sPLA2 and peroxisome proliferator-activated receptor alpha activation.
The Journal of biological chemistry 2003;278(32):29799-812.
2003: Sophie Chabot; Kamen Koumanov; Gérard Lambeau; Michael H Gelb; Viviane Balloy; Michel Chignard; Jeffrey A Whitsett; Lhousseine Touqui
Inhibitory effects of surfactant protein A on surfactant phospholipid hydrolysis by secreted phospholipases A2.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):995-1000.
2003: Silvia Gurrieri; Gerhard Fürstenberger; Alexia Schadow; Ulrike Haas; Alan G Singer; Farideh Ghomashchi; Josef Pfeilschifter; Gérard Lambeau; Michael H Gelb; Marietta Kaszkin
Differentiation-dependent regulation of secreted phospholipases A2 in murine epidermis.
The Journal of investigative dermatology 2003;121(1):156-64.
2003: pierre escoubas; Cédric Bernard; Gérard Lambeau; Michel Lazdunski; Hervé Darbon
Recombinant production and solution structure of PcTx1, the specific peptide inhibitor of ASIC1a proton-gated cation channels.
Protein science : a publication of the Protein Society 2003;12(7):1332-43.
2003: Makoto Murakami; Seiko Masuda; Satoko Shimbara; Laboratoire Biochimie et Genie Enzymatique des Lipases; Michael Lazdunski; Gérard Lambeau; Michael H Gelb; Satoshi Matsukura; Fumio Kokubu; Mitsuru Adachi; Ichiro Kudo
Cellular arachidonate-releasing function of novel classes of secretory phospholipase A2s (groups III and XII).
The Journal of biological chemistry 2003;278(12):10657-67.
2003: Mei Dong; Kishore Guda; Prashant R Nambiar; Anahita Rezaie; Glenn S Belinsky; Gérard Lambeau; Charles Giardina; Daniel W Rosenberg
Inverse association between phospholipase A2 and COX-2 expression during mouse colon tumorigenesis.
Carcinogenesis 2003;24(2):307-15.
2002: Alan G Singer; Farideh Ghomashchi; Catherine Le Calvez; James Bollinger; Laboratoire Biochimie et Genie Enzymatique des Lipases; Morgane Rouault; Martin Sadilek; Eric Nguyen; Michel Lazdunski; Gérard Lambeau; Michael H Gelb
Interfacial kinetic and binding properties of the complete set of human and mouse groups I, II, V, X, and XII secreted phospholipases A2.
The Journal of biological chemistry 2002;277(50):48535-49.
2002: Ying H Pan; Bao-Zhu Yu; Alan G Singer; Farideh Ghomashchi; Gérard Lambeau; Michael H Gelb; Mahendra K Jain; Brian J Bahnson
Crystal structure of human group X secreted phospholipase A2. Electrostatically neutral interfacial surface targets zwitterionic membranes.
The Journal of biological chemistry 2002;277(32):29086-93.
2002: Makoto Murakami; Kumiko Yoshihara; Satoko Shimbara; Gérard Lambeau; Michael H Gelb; Alan G Singer; Masatsugu Sawada; Naoki Inagaki; Hiroichi Nagai; Motoko Ishihara; Yukio Ishikawa; Toshiharu Ishii; Ichiro Kudo
Cellular arachidonate-releasing function and inflammation-associated expression of group IIF secretory phospholipase A2.
The Journal of biological chemistry 2002;277(21):19145-55.
2002: Makoto Murakami; Kumiko Yoshihara; Satoko Shimbara; Gérard Lambeau; Alan Singer; Michael H Gelb; Masatsugu Sawada; Naoki Inagaki; Hiroichi Nagai; Ichiro Kudo
Arachidonate release and eicosanoid generation by group IIE phospholipase A(2).
Biochemical and biophysical research communications 2002;292(3):689-96.
2002: Mark DeCoster; Gérard Lambeau; Michel Lazdunski; Nicolas G Bazan
Secreted phospholipase A2 potentiates glutamate-induced calcium increase and cell death in primary neuronal cultures.
Journal of neuroscience research 2002;67(5):634-45.
2002: Rao S Koduri; Juha Grönroos; Jukka Laine; Catherine Le Calvez; Gérard Lambeau; Timo J Nevalainen; Michael H Gelb
Bactericidal properties of human and murine groups I, II, V, X, and XII secreted phospholipases A(2).
The Journal of biological chemistry 2002;277(8):5849-57.
2002: Norbert Degousee; Farideh Ghomashchi; Eva Stefanski; Alan Singer; Brian P Smart; Niels Borregaard; Reinhardt Reithmeier; Thomas F Lindsay; Cornelia Lichtenberger; Walter Reinisch; Gérard Lambeau; Jonathan Arm; Jay A Tischfield; Michael H Gelb; Barry B Rubin
Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis.
The Journal of biological chemistry 2002;277(7):5061-73.
2001: David Fenard; Gérard Lambeau; Thomas Maurin; Jean-Claude Lefebvre; Alain Doglio
A peptide derived from bee venom-secreted phospholipase A2 inhibits replication of T-cell tropic HIV-1 strains via interaction with the CXCR4 chemokine receptor.
Molecular pharmacology 2001;60(2):341-7.
2001: Makoto Murakami; Rao S Koduri; A Enomoto; Satoko Shimbara; M Seki; Kumiko Yoshihara; A Singer; Eulogio Valentin; Farideh Ghomashchi; Gérard Lambeau; Michael H Gelb; Ichiro Kudo
Distinct arachidonate-releasing functions of mammalian secreted phospholipase A2s in human embryonic kidney 293 and rat mastocytoma RBL-2H3 cells through heparan sulfate shuttling and external plasma membrane mechanisms.
The Journal of biological chemistry 2001;276(13):10083-96.
2001: Alexia Schadow; Kristen Scholz-Pedretti; Gérard Lambeau; Michael H Gelb; Gerhard Fürstenberger; Josef Pfeilschifter; Marietta Kaszkin
Characterization of group X phospholipase A(2) as the major enzyme secreted by human keratinocytes and its regulation by the phorbol ester TPA.
The Journal of investigative dermatology 2001;116(1):31-9.
2000: Michael H Gelb; Eulogio Valentin; Farideh Ghomashchi; Michel Lazdunski; Gérard Lambeau
Cloning and recombinant expression of a structurally novel human secreted phospholipase A2.
The Journal of biological chemistry 2000;275(51):39823-6.
2000: Eulogio Valentin; Alan G Singer; Farideh Ghomashchi; Michel Lazdunski; Michael H Gelb; Gérard Lambeau
Cloning and recombinant expression of human group IIF-secreted phospholipase A(2).
Biochemical and biophysical research communications 2000;279(1):223-8.
2000: Eulogio Valentin; Gérard Lambeau
Increasing molecular diversity of secreted phospholipases A(2) and their receptors and binding proteins.
Biochimica et biophysica acta 2000;1488(1-2):59-70.
2000: A Enomoto; Makoto Murakami; Eulogio Valentin; Gérard Lambeau; Michael H Gelb; Ichiro Kudo
Redundant and segregated functions of granule-associated heparin-binding group II subfamily of secretory phospholipases A2 in the regulation of degranulation and prostaglandin D2 synthesis in mast cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(7):4007-14.
2000: Eulogio Valentin; Gérard Lambeau
What can venom phospholipases A(2) tell us about the functional diversity of mammalian secreted phospholipases A(2)?
Biochimie 2000;82(9-10):815-31.
2000: Carine M Mounier; P Luchetta; C Lecut; Rao S Koduri; Grazyna FAURE; Gérard Lambeau; Eulogio Valentin; A Singer; Farideh Ghomashchi; S Béguin; M H Gelb; Cassian Bon
Basic residues of human group IIA phospholipase A2 are important for binding to factor Xa and prothrombinase inhibition comparison with other mammalian secreted phospholipases A2.
European journal of biochemistry / FEBS 2000;267(16):4960-9.
2000: Eulogio Valentin; Farideh Ghomashchi; Michael H Gelb; Michel Lazdunski; Gérard Lambeau
Novel human secreted phospholipase A(2) with homology to the group III bee venom enzyme.
The Journal of biological chemistry 2000;275(11):7492-6.
2000: Laboratoire Biochimie et Genie Enzymatique des Lipases; Rao S Koduri; Eulogio Valentin; Makoto Murakami; Ichiro Kudo; Farideh Ghomashchi; Martin Sadilek; Gérard Lambeau; Michael H Gelb
Exogenously added human group X secreted phospholipase A(2) but not the group IB, IIA, and V enzymes efficiently release arachidonic acid from adherent mammalian cells.
The Journal of biological chemistry 2000;275(5):3179-91.
1999: Eulogio Valentin; Farideh Ghomashchi; Michael H Gelb; Michel Lazdunski; Gérard Lambeau
On the diversity of secreted phospholipases A(2). Cloning, tissue distribution, and functional expression of two novel mouse group II enzymes.
The Journal of biological chemistry 1999;274(44):31195-202.
1999: David Fenard; Gérard Lambeau; Eulogio Valentin; Jean-Claude Lefebvre; Michel Lazdunski; Alain Doglio
Secreted phospholipases A(2), a new class of HIV inhibitors that block virus entry into host cells.
The Journal of clinical investigation 1999;104(5):611-8.
1999: Eulogio Valentin; Rao S Koduri; Jean-Claude Scimeca; Georges F Carle; Michael H Gelb; Michel Lazdunski; Gérard Lambeau
Cloning and recombinant expression of a novel mouse-secreted phospholipase A2.
The Journal of biological chemistry 1999;274(27):19152-60.
1999: Gérard Lambeau; M Lazdunski
Receptors for a growing family of secreted phospholipases A2.
Trends in pharmacological sciences 1999;20(4):162-70.
1999: L Cupillard; R Mulherkar; N Gomez; S Kadam; Eulogio Valentin; Michel Lazdunski; Gérard Lambeau
Both group IB and group IIA secreted phospholipases A2 are natural ligands of the mouse 180-kDa M-type receptor.
The Journal of biological chemistry 1999;274(11):7043-51.
1997: L Cupillard; Kamen Koumanov; M G Mattéi; Michel Lazdunski; Gérard Lambeau
Cloning, chromosomal mapping, and expression of a novel human secretory phospholipase A2.
The Journal of biological chemistry 1997;272(25):15745-52.
1997: J P Nicolas; Y Lin; Gérard Lambeau; Farideh Ghomashchi; Michel Lazdunski; Michael H Gelb
Localization of structural elements of bee venom phospholipase A2 involved in N-type receptor binding and neurotoxicity.
The Journal of biological chemistry 1997;272(11):7173-81.
1996: E Zvaritch; Gérard Lambeau; Michel Lazdunski
Endocytic properties of the M-type 180-kDa receptor for secretory phospholipases A2.
The Journal of biological chemistry 1996;271(1):250-7.
1996: Gérard Lambeau; Philippe Ancian; J P Nicolas; L Cupillard; E Zvaritch; Michel Lazdunski
[A family of receptors for secretory phospholipases A2].
Comptes rendus des séances de la Société de biologie et de ses filiales 1996;190(4):425-35.
1995: J P Nicolas; Gérard Lambeau; Michel Lazdunski
Identification of the binding domain for secretory phospholipases A2 on their M-type 180-kDa membrane receptor.
The Journal of biological chemistry 1995;270(48):28869-73.
1995: Philippe Ancian; Gérard Lambeau; Michel Lazdunski
Multifunctional activity of the extracellular domain of the M-type (180 kDa) membrane receptor for secretory phospholipases A2.
Biochemistry 1995;34(40):13146-51.
1995: Philippe Ancian; Gérard Lambeau; M G Mattéi; Michel Lazdunski
The human 180-kDa receptor for secretory phospholipases A2. Molecular cloning, identification of a secreted soluble form, expression, and chromosomal localization.
The Journal of biological chemistry 1995;270(15):8963-70.
1995: Gérard Lambeau; Philippe Ancian; J P Nicolas; S H Beiboer; D Moinier; H Verheij; Michel Lazdunski
Structural elements of secretory phospholipases A2 involved in the binding to M-type receptors.
The Journal of biological chemistry 1995;270(10):5534-40.
1994: Gérard Lambeau; Philippe Ancian; Jacques Barhanin; Michel Lazdunski
Cloning and expression of a membrane receptor for secretory phospholipases A2.
The Journal of biological chemistry 1994;269(3):1575-8.
1991: Gérard Lambeau; Jacques Barhanin; Michel Lazdunski
Identification of different receptor types for toxic phospholipases A2 in rabbit skeletal muscle.
FEBS letters 1991;293(1-2):29-33.
1991: Gérard Lambeau; M Lazdunski; Jacques Barhanin
Properties of receptors for neurotoxic phospholipases A2 in different tissues.
Neurochemical research 1991;16(6):651-8.
1990: Gérard Lambeau; Annie Schmid-Alliana; Michel Lazdunski; Jacques Barhanin
Identification and purification of a very high affinity binding protein for toxic phospholipases A2 in skeletal muscle.
The Journal of biological chemistry 1990;265(16):9526-32.
1989: Gérard Lambeau; Jacques Barhanin; H Schweitz; J Qar; Michel Lazdunski
Identification and properties of very high affinity brain membrane-binding sites for a neurotoxic phospholipase from the taipan venom.
The Journal of biological chemistry 1989;264(19):11503-10.