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Philippe Lambin

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Bram L T Ramaekers; Madelon Pijls-Johannesma; Janneke P C Grutters; Manuela A Joore; Philippe Lambin; Johannes A Langendijk
Protons in head-and-neck cancer: bridging the gap of evidence.
Bart Reymen; Angela van Baardwijk; Judith Van Loon; Rinus Wanders; Anne-Marie C Dingemans; Wiel Geraedts; Philippe Lambin; Ragnar Lunde; Cordula Pitz; Gerben Bootsma; Jacques Borger; Dirk De Ruysscher
Total gross tumor volume is an independent prognostic factor in patients treated with selective nodal irradiation for stage I to III small cell lung cancer.
Mathieu Hatt; Guido Lammering; Adrien le Pogam; Ruud van Stiphout; Dimitris Visvikis; Philippe Lambin
Early prediction of pathological response in locally advanced rectal cancer based on sequential 18F-FDG PET.

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2013: Bram L T Ramaekers; Madelon Pijls-Johannesma; Janneke P C Grutters; Manuela A Joore; Philippe Lambin; Johannes A Langendijk
Protons in head-and-neck cancer: bridging the gap of evidence.
International journal of radiation oncology, biology, physics 2013;85(5):1282-8.
2013: Bart Reymen; Angela van Baardwijk; Judith Van Loon; Rinus Wanders; Anne-Marie C Dingemans; Wiel Geraedts; Philippe Lambin; Ragnar Lunde; Cordula Pitz; Gerben Bootsma; Jacques Borger; Dirk De Ruysscher
Total gross tumor volume is an independent prognostic factor in patients treated with selective nodal irradiation for stage I to III small cell lung cancer.
International journal of radiation oncology, biology, physics 2013;85(5):1319-24.
2013: Mathieu Hatt; Guido Lammering; Adrien le Pogam; Ruud van Stiphout; Dimitris Visvikis; Philippe Lambin
Early prediction of pathological response in locally advanced rectal cancer based on sequential 18F-FDG PET.
Acta oncologica (Stockholm, Sweden) 2013;52(3):619-26.
2013: Kasper M A Rouschop; Twan van den Beucken; Albert J van der Kogel; Johan Bussink; Ludwig J Dubois; Tom G Keulers; Marianne Koritzinsky; Philippe Lambin; Bradly G Wouters
PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(12):4622-7.
2013: Dirk De Ruysscher; Frank Hoebers; José Belderbos; Michel Ollers; Bart Reymen; Angela van Baardwijk; Wouter van Elmpt; Marc Vooijs; Rinus Wanders; Philippe Lambin
State of the art radiation therapy for lung cancer 2012: a glimpse of the future.
Clinical lung cancer 2013;14(2):89-95.
2013: Philippe Lambin; Georgi Nalbantov; Emmanuel Rios-Velazquez; Erik Roelofs; Maud H W Starmans; Vincenzo Valentini; Wouter van Elmpt; Ruud G P M van Stiphout; Hugo J W L Aerts; Adrian C Begg; Paul C Boutros; Dirk De Ruysscher; Pierluigi Granone; Andre Dekker
Predicting outcomes in radiation oncology--multifactorial decision support systems.
Nature reviews. Clinical oncology 2013;10(1):27-40.
2012: An M Voets; Wilfried De Neve; Kim De Ruyck; Dirk De Ruysscher; Cary Oberije; Bart Reymen; Hubert J M Smeets; Robin B Struijk; Hubert Thierens; Katrien Vandecasteele; Ruud Houben; Philippe Lambin
No association between TGF-β1 polymorphisms and radiation-induced lung toxicity in a European cohort of lung cancer patients.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2012;105(3):296-8.
2012: Dirk De Ruysscher; Anne-Marie C Dingemans; Wiel Geraedts; Ruud Houben; Cordula Pitz; Bart Reymen; Angela van Baardwijk; Linda van Eijsden; Rinus Wanders; Brigitta Baumert; Gerben Bootsma; Philippe Lambin
Radical treatment of non-small-cell lung cancer patients with synchronous oligometastases: long-term results of a prospective phase II trial (Nct01282450).
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2012;7(10):1547-55.
2012: Wouter van Elmpt; Anne-Marie C Dingemans; Philippe Lambin; Michel Ollers; Dirk De Ruysscher
Response assessment using 18F-FDG PET early in the course of radiotherapy correlates with survival in advanced-stage non-small cell lung cancer.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2012;53(10):1514-20.
2012: Angela van Baardwijk; Stofferinus Wanders; Gerben Bootsma; Jacques Borger; Anne-Marie C Dingemans; Wiel Geraedts; Philippe Lambin; Ragnar Lunde; Michel Ollers; Frank Peters; Cordula Pitz; Bart Reymen; Dirk De Ruysscher
Mature results of a phase II trial on individualised accelerated radiotherapy based on normal tissue constraints in concurrent chemo-radiation for stage III non-small cell lung cancer.
European journal of cancer (Oxford, England : 1990) 2012;48(15):2339-46.
2012: M H W Starmans; F C G J Sweep; H W van Laarhoven; Bradly G Wouters; P C Boutros; L Dubois; S Haider; Natasja Lieuwes; F Nguyen; P N Span; Philippe Lambin
Independent and functional validation of a multi-tumour-type proliferation signature.
British journal of cancer 2012;107(3):508-15.
2012: Dirk De Ruysscher; A M C Dingemans; Philippe Lambin; Guido Lammering; C Oberije; Madelon Pijls-Johannesma; B Reymen; Angela van Baardwijk; J Van Meerbeeck; Katrien Vandecasteele; R Wanders; Wilfried De Neve
Radiation-induced oesophagitis in lung cancer patients. Is susceptibility for neutropenia a risk factor?
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 2012;188(7):564-7.
2012: Maud H W Starmans; Bradly G Wouters; Michaël G Magagnin; Francis Nguyen; Renaud Seigneuric; Paul C Boutros; Kenneth C Chu; Syed Haider; Arek Kasprzyk; Marianne Koritzinsky; Philippe Lambin
The prognostic value of temporal in vitro and in vivo derived hypoxia gene-expression signatures in breast cancer.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2012;102(3):436-43.
2012: Jeroen Buijsen; Stephanie Engelsman; Marco Janssen; Philippe Lambin; Geerard L Beets; Regina G H Beets-Tan; Jørgen van den Bogaard; Hiska van der Weide; Ruud van Stiphout; Guido Lammering
FDG-PET-CT reduces the interobserver variability in rectal tumor delineation.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2012;102(3):371-6.
2012: Philippe Lambin; Ralph Leijenaar; Emmanuel Rios-Velazquez; Ruud G P M van Stiphout; Catharina M L Zegers; Ronald Boellard; Sara Carvalho; André Dekker; Robert Gillies; Patrick Granton; Hugo J W L Aerts
Radiomics: extracting more information from medical images using advanced feature analysis.
European journal of cancer (Oxford, England : 1990) 2012;48(4):441-6.
2012: Dirk De Ruysscher; Andre Dekker; Anne-Marie C Dingemans; Wiel Geraedts; Gerben Bootsma; Jacques Borger; Geert Bosmans; Anita Botterweck; Ragnar Lunde; Michel Oellers; Cordula Pitz; Bart Reymen; Jessie Steevens; Angela van Baardwijk; Rinus Wanders; Philippe Lambin
Individualised isotoxic accelerated radiotherapy and chemotherapy are associated with improved long-term survival of patients with stage III NSCLC: a prospective population-based study.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2012;102(2):228-33.
2012: Marco H M Janssen; Philippe Lambin; Guido Lammering; Hugo J W L Aerts; Jeroen Buijsen; Michel Ollers
Repeated positron emission tomography-computed tomography and perfusion-computed tomography imaging in rectal cancer: fluorodeoxyglucose uptake corresponds with tumor perfusion.
International journal of radiation oncology, biology, physics 2012;82(2):849-55.
2012: Marco H M Janssen; Philippe Lambin; Jeroen Buijsen; Robert G Riedl; Jørgen van den Bogaard; Ruud G P M van Stiphout; Michel Ollers; Guido Lammering
PET-based treatment response evaluation in rectal cancer: prediction and validation.
International journal of radiation oncology, biology, physics 2012;82(2):871-6.
2012: Erik Roelofs; Frank Verhaegen; Dirk De Ruysscher; Martijn Engelsman; Philippe Lambin; Lucas Persoon; Madelon Pijls-Johannesma; Sima Qamhiyeh; Coen Rasch
Results of a multicentric in silico clinical trial (ROCOCO): comparing radiotherapy with photons and protons for non-small cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2012;7(1):165-76.
2011: Rinus Wanders; Angela van Baardwijk; Gerben Bootsma; Jacques Borger; Anita Botterweck; Anne-Marie C Dingemans; Wiel Geraedts; Philippe Lambin; Ragnar Lunde; Cordula Pitz; Bart Reymen; Jessie Steevens; Dirk De Ruysscher
Treatment with curative intent of stage III non-small cell lung cancer patients of 75 years: a prospective population-based study.
European journal of cancer (Oxford, England : 1990) 2011;47(18):2691-7.
2011: Dirk De Ruysscher; Wouter van Elmpt; Philippe Lambin
Radiotherapy with curative intent for lung cancer: a continuing success story.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2011;101(2):237-9.
2011: Steven F Petit; Wouter J C van Elmpt; Erik Vegt; André L A J Dekker; Anne-Marie C Dingemans; Philippe Lambin; Cary J G Oberije; Dirk De Ruysscher
[¹⁸F]fluorodeoxyglucose uptake patterns in lung before radiotherapy identify areas more susceptible to radiation-induced lung toxicity in non-small-cell lung cancer patients.
International journal of radiation oncology, biology, physics 2011;81(3):698-705.
2011: Laurent Quero; Natasja Lieuwes; Ludwig Dubois; Christophe Hennequin; Philippe Lambin
miR-210 as a marker of chronic hypoxia, but not a therapeutic target in prostate cancer.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2011;101(1):203-8.
2011: Cary Dehing-Oberije; Mika Hilvo; Hugo Aerts; Dirk De Ruysscher; Paul Menheere; Bharat Rao; Hiska van der Weide; Shipeng Yu; Philippe Lambin
Development and validation of a prognostic model using blood biomarker information for prediction of survival of non-small-cell lung cancer patients treated with combined chemotherapy and radiation or radiotherapy alone (NCT00181519, NCT00573040, and NCT00572325).
International journal of radiation oncology, biology, physics 2011;81(2):360-8.
2011: Bram L T Ramaekers; Piet van den Ende; Madelon Pijls-Johannesma; Ivo Beetz; Miranda Christianen; Janneke P C Grutters; Ruud Houben; Jos de Jong; Manuela A Joore; Philippe Lambin; Johannes A Langendijk
The impact of late treatment-toxicity on generic health-related quality of life in head and neck cancer patients after radiotherapy.
Oral oncology 2011;47(8):768-74.
2011: Ada G T M Egelmeer; Yasmyne Geussens; Frank Hoebers; Jarrod Homer; Bernd Kremer; Jos M A de Jong; Monique C de Jong; C René Leemans; Sandra Nuyts; Cary Oberije; Coen Rasch; Derek Rietveld; Nick Slevin; E Rios Velazquez; Catharine West; Philippe Lambin
Development and validation of a nomogram for prediction of survival and local control in laryngeal carcinoma patients treated with radiotherapy alone: a cohort study based on 994 patients.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2011;100(1):108-15.
2011: Twan van den Beucken; Barry Jutten; Marianne Koritzinsky; Philippe Lambin; Michaël G Magagnin; Renaud Seigneuric; Bradly G Wouters
Translational control is a major contributor to hypoxia induced gene expression.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2011;99(3):379-84.
2011: Jan Theys; Bradly G Wouters; Arjan J Groot; Roger Habets; Barry Jutten; Philippe Lambin; Guido Lammering; Kim Paesmans; Marc Vooijs
E-Cadherin loss associated with EMT promotes radioresistance in human tumor cells.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2011;99(3):392-7.
2011: Ludwig Dubois; Nele Geusens; Adrian L Harris; Fabrizio Carta; Jean-Michel Dogné; Natasja Lieuwes; Bernard Masereel; Alan McIntyre; Sarah Peeters; Andrea Scozzafava; Claudiu T Supuran; Anne Thiry; Simon Wigfield; Philippe Lambin
Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2011;99(3):424-31.
2011: Jørgen van den Bogaard; Marco H M Janssen; G Janssens; Jeroen Buijsen; Brigitte Reniers; Philippe Lambin; Guido Lammering; Michel Ollers
Residual metabolic tumor activity after chemo-radiotherapy is mainly located in initially high FDG uptake areas in rectal cancer.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2011;99(2):137-41.
2011: Judith van Loon; Claudia Offermann; Michel Ollers; Wouter van Elmpt; Erik Vegt; Ali Rahmy; Anne-Marie C Dingemans; Philippe Lambin; Dirk De Ruysscher
Early CT and FDG-metabolic tumour volume changes show a significant correlation with survival in stage I-III small cell lung cancer: a hypothesis generating study.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2011;99(2):172-5.
2011: Wouter van Elmpt; James Hamill; Judson Jones; Dirk De Ruysscher; Philippe Lambin; Michel Ollers
Optimal gating compared to 3D and 4D PET reconstruction for characterization of lung tumours.
European journal of nuclear medicine and molecular imaging 2011;38(5):843-55.
2011: Bram L T Ramaekers; Madelon Pijls-Johannesma; Manuela A Joore; Piet van den Ende; Johannes A Langendijk; Philippe Lambin; Alfons G H Kessels; Janneke P C Grutters
Systematic review and meta-analysis of radiotherapy in various head and neck cancers: comparing photons, carbon-ions and protons.
Cancer treatment reviews 2011;37(3):185-201.
2011: Jeroen Buijsen; Jørgen van den Bogaard; Marco H M Janssen; Frans C H Bakers; Stephanie Engelsman; Michel Öllers; Regina G H Beets-Tan; Marius Nap; Geerard L Beets; Philippe Lambin; Guido Lammering
FDG-PET provides the best correlation with the tumor specimen compared to MRI and CT in rectal cancer.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2011;98(2):270-6.
2011: Ruud G P M van Stiphout; Guido Lammering; Jeroen Buijsen; Marco H M Janssen; Maria Antonietta Gambacorta; Pieter Slagmolen; Maarten Lambrecht; Domenico Rubello; Marcello Gava; Alessandro Giordano; Eric O Postma; Karin Haustermans; Carlo Capirci; Vincenzo Valentini; Philippe Lambin
Development and external validation of a predictive model for pathological complete response of rectal cancer patients including sequential PET-CT imaging.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2011;98(1):126-33.
2010: Cary Dehing-Oberije; Dirk De Ruysscher; Steven Petit; Jan Van Meerbeeck; Katrien Vandecasteele; Wilfried De Neve; Anne Marie C Dingemans; Issam El-Naqa; Joseph Deasy; Jeff Bradley; Ellen Huang; Philippe Lambin
Development, external validation and clinical usefulness of a practical prediction model for radiation-induced dysphagia in lung cancer patients.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2010;97(3):455-61.
2010: Erik Roelofs; Lucas Persoon; Sima Qamhiyeh; Frank Verhaegen; Dirk De Ruysscher; Michael Scholz; Gheorghe Iancu; Martijn Engelsman; Coen Rasch; Lambert Zijp; Gert De Meerleer; Marc Coghe; Johannes Langendijk; Cornelis Schilstra; Madelon Pijls-Johannesma; Philippe Lambin
Design of and technical challenges involved in a framework for multicentric radiotherapy treatment planning studies.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2010;97(3):567-71.
2010: Hugo Aerts; Philippe Lambin; Dirk De Ruysscher
FDG for dose painting: a rational choice.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2010;97(2):163-4.
2010: Janneke P C Grutters; Manuela A Joore; Erwin M Wiegman; Johannes A Langendijk; Dirk De Ruysscher; Monique Hochstenbag; Anita Botterweck; Philippe Lambin; Madelon Pijls-Johannesma
Health-related quality of life in patients surviving non-small cell lung cancer.
Thorax 2010;65(10):903-7.
2010: Emmanuel Rios Velazquez; Hugo Aerts; Cary Oberije; Dirk De Ruysscher; Philippe Lambin
Prediction of residual metabolic activity after treatment in NSCLC patients.
Acta oncologica (Stockholm, Sweden) 2010;49(7):1033-9.
2010: Janneke P C Grutters; Madelon Pijls-Johannesma; Dirk De Ruysscher; Andrea Peeters; Stefan Reimoser; Johan L Severens; Philippe Lambin; Manuela A Joore
The cost-effectiveness of particle therapy in non-small cell lung cancer: exploring decision uncertainty and areas for future research.
Cancer treatment reviews 2010;36(6):468-76.
2010: Philippe Lambin; Steven F Petit; Hugo Aerts; Wouter J C van Elmpt; Cary J G Oberije; Maud H W Starmans; Ruud G P M van Stiphout; Guus A M S van Dongen; Kristoff Muylle; Patrick Flamen; André L A J Dekker; Dirk De Ruysscher
The ESTRO Breur Lecture 2009. From population to voxel-based radiotherapy: exploiting intra-tumour and intra-organ heterogeneity for advanced treatment of non-small cell lung cancer.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2010;96(2):145-52.
2010: Judith van Loon; Marco H M Janssen; Michel Ollers; Hugo Aerts; Ludwig Dubois; Monique Hochstenbag; Anne-Marie C Dingemans; Roy Lalisang; Boudewijn Brans; Bert Windhorst; Guus A van Dongen; Hartmuth Kolb; James Zhang; Dirk De Ruysscher; Philippe Lambin
PET imaging of hypoxia using [18F]HX4: a phase I trial.
European journal of nuclear medicine and molecular imaging 2010;37(9):1663-8.
2010: Vamsidhar Akurathi; Ludwig Dubois; Natasja G Lieuwes; Satish K Chitneni; Bernard J Cleynhens; Daniela Vullo; Claudiu T Supuran; Alfons Verbruggen; Philippe Lambin; Guy Bormans
Synthesis and biological evaluation of a 99mTc-labelled sulfonamide conjugate for in vivo visualization of carbonic anhydrase IX expression in tumor hypoxia.
Nuclear medicine and biology 2010;37(5):557-64.
2010: Judith van Loon; Dirk De Ruysscher; Rinus Wanders; Liesbeth J Boersma; Jean Simons; Michel Oellers; Anne-Marie C Dingemans; Monique Hochstenbag; Gerben Bootsma; Wiel Geraedts; Cordula Pitz; Jaap Teule; Ali Rhami; Willy Thimister; Gabriel Snoep; Cary Dehing-Oberije; Philippe Lambin
Selective nodal irradiation on basis of (18)FDG-PET scans in limited-disease small-cell lung cancer: a prospective study.
International journal of radiation oncology, biology, physics 2010;77(2):329-36.
2010: Roel G J Kierkels; Walter H Backes; Marco H M Janssen; Jeroen Buijsen; Regina G H Beets-Tan; Philippe Lambin; Guido Lammering; Michel C Oellers; Hugo Aerts
Comparison between perfusion computed tomography and dynamic contrast-enhanced magnetic resonance imaging in rectal cancer.
International journal of radiation oncology, biology, physics 2010;77(2):400-8.
2010: Marco H M Janssen; Michel Ollers; Robert G Riedl; Jørgen van den Bogaard; Jeroen Buijsen; Ruud G P M van Stiphout; Hugo Aerts; Philippe Lambin; Guido Lammering
Accurate prediction of pathological rectal tumor response after two weeks of preoperative radiochemotherapy using (18)F-fluorodeoxyglucose-positron emission tomography-computed tomography imaging.
International journal of radiation oncology, biology, physics 2010;77(2):392-9.
2010: Madelon Pijls-Johannesma; Ghislaine van Mastrigt; Steve M Hahn; Dirk De Ruysscher; Brigitta Baumert; Guido Lammering; Jeroen Buijsen; Søren M Bentzen; Yolande Lievens; Andrew Kramar; Philippe Lambin
A systematic methodology review of phase I radiation dose escalation trials.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2010;95(2):135-41.
2010: Marco H M Janssen; Michel Ollers; Ruud G P M van Stiphout; Robert G Riedl; Jørgen van den Bogaard; Jeroen Buijsen; Philippe Lambin; Guido Lammering
Blood glucose level normalization and accurate timing improves the accuracy of PET-based treatment response predictions in rectal cancer.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2010;95(2):203-8.
2010: Janneke P C Grutters; Alfons G H Kessels; Madelon Pijls-Johannesma; Dirk De Ruysscher; Manuela A Joore; Philippe Lambin
Comparison of the effectiveness of radiotherapy with photons, protons and carbon-ions for non-small cell lung cancer: a meta-analysis.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2010;95(1):32-40.
2010: Angela van Baardwijk; Stofferinus Wanders; Liesbeth J Boersma; Jacques Borger; Michel Ollers; Anne-Marie C Dingemans; Gerben Bootsma; Wiel Geraedts; Cordula Pitz; Ragnar Lunde; Philippe Lambin; Dirk De Ruysscher
Mature results of an individualized radiation dose prescription study based on normal tissue constraints in stages I to III non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(8):1380-6.
2010: Steven F Petit; Wouter J C van Elmpt; Philippe Lambin; André L A J Dekker
Dose recalculation in megavoltage cone-beam CT for treatment evaluation: removal of cupping and truncation artefacts in scans of the thorax and abdomen.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2010;94(3):359-66.
2010: Marco H M Janssen; Michel Ollers; Ruud G P M van Stiphout; Jeroen Buijsen; Jørgen van den Bogaard; Dirk De Ruysscher; Philippe Lambin; Guido Lammering
Evaluation of early metabolic responses in rectal cancer during combined radiochemotherapy or radiotherapy alone: sequential FDG-PET-CT findings.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2010;94(2):151-5.
2010: Wouter van Elmpt; Steven Petit; Dirk De Ruysscher; Philippe Lambin; André Dekker
3D dose delivery verification using repeated cone-beam imaging and EPID dosimetry for stereotactic body radiotherapy of non-small cell lung cancer.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2010;94(2):188-94.
2010: Marco H M Janssen; Hugo Aerts; Roel G J Kierkels; Walter H Backes; Michel Ollers; Jeroen Buijsen; Philippe Lambin; Guido Lammering
Tumor perfusion increases during hypofractionated short-course radiotherapy in rectal cancer: sequential perfusion-CT findings.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2010;94(2):156-60.
2010: Ludy Lutgens; Jacoba van der Zee; Madelon Pijls-Johannesma; Danielle Fm De Haas-Kock; Jeroen Buijsen; Ghislaine Apg van Mastrigt; Guido Lammering; Dirk De Ruysscher; Philippe Lambin
Combined use of hyperthermia and radiation therapy for treating locally advanced cervix carcinoma.
Cochrane database of systematic reviews (Online) 2010;(3):CD006377.
2010: Ludy Lutgens; Jacoba van der Zee; Madelon Pijls-Johannesma; Danielle Fm De Haas-Kock; Jeroen Buijsen; Ghislaine Apg van Mastrigt; Guido Lammering; Dirk K M De Ruysscher; Philippe Lambin
Combined use of hyperthermia and radiation therapy for treating locally advanced cervical carcinoma.
Cochrane database of systematic reviews (Online) 2010;(1):CD006377.
2010: Kasper M A Rouschop; Twan van den Beucken; Ludwig Dubois; Hanneke Niessen; Johan Bussink; Kim Savelkouls; Tom Keulers; Hilda Mujcic; Willy Landuyt; Jan Willem Voncken; Philippe Lambin; Albert J van der Kogel; Marianne Koritzinsky; Bradly G Wouters
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.
The Journal of clinical investigation 2010;120(1):127-41.
2010: Jos J Jager; Kristien Keymeulen; Regina G H Beets-Tan; Pierre Hupperets; Marinus Van Kroonenburgh; Ruud Houben; Dirk De Ruysscher; Philippe Lambin; Liesbeth J Boersma
FDG-PET-CT for staging of high-risk breast cancer patients reduces the number of further examinations: A pilot study.
Acta oncologica (Stockholm, Sweden) 2010;49(2):185-91.
2010: Judith van Loon; Janneke P C Grutters; Rinus Wanders; Liesbeth J Boersma; Anne-Marie C Dingemans; Gerben Bootsma; Wiel Geraedts; Cordula Pitz; Jean Simons; Boudewijn Brans; Gabriel Snoep; Monique Hochstenbag; Philippe Lambin; Dirk De Ruysscher
18FDG-PET-CT in the follow-up of non-small cell lung cancer patients after radical radiotherapy with or without chemotherapy: an economic evaluation.
European journal of cancer (Oxford, England : 1990) 2010;46(1):110-9.
2009: Dirk De Ruysscher; Cary Dehing; Søren M Bentzen; Ruud Houben; André Dekker; Rinus Wanders; Jacques Borger; Monique Hochstenbag; Liesbeth J Boersma; Gijs Geskes; Anne-Marie C Dingemans; Gerben Bootsma; Guido Lammering; Philippe Lambin
Can we optimize chemo-radiation and surgery in locally advanced stage III non-small cell lung cancer based on evidence from randomized clinical trials? A hypothesis-generating study.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009;93(3):389-95.
2009: Esther J Bloemen-van Gurp; Björk K C Haanstra; Lars H P Murrer; Francis C J M van Gils; André L A J Dekker; Ben J Mijnheer; Philippe Lambin
In vivo dosimetry with a linear MOSFET array to evaluate the urethra dose during permanent implant brachytherapy using iodine-125.
International journal of radiation oncology, biology, physics 2009;75(4):1266-72.
2009: Twan van den Beucken; Marianne Koritzinsky; Hanneke Niessen; Ludwig Dubois; Kim Savelkouls; Hilda Mujcic; Barry Jutten; Juraj Kopacek; Sylvia Pastorekova; Albert J van der Kogel; Philippe Lambin; Willem Voncken; Kasper M A Rouschop; Bradly G Wouters
Hypoxia-induced expression of carbonic anhydrase 9 is dependent on the unfolded protein response.
The Journal of biological chemistry 2009;284(36):24204-12.
2009: Guillaume Janssens; Jonathan Orban de Xivry; Stein Fekkes; André Dekker; Benoît Macq; Philippe Lambin; Wouter van Elmpt
Evaluation of nonrigid registration models for interfraction dose accumulation in radiotherapy.
Medical physics 2009;36(9):4268-76.
2009: Kasper M A Rouschop; Chantal H M A Ramaekers; Marco B E Schaaf; Tom G H Keulers; Kim Savelkouls; Philippe Lambin; Marianne Koritzinsky; Bradly G Wouters
Autophagy is required during cycling hypoxia to lower production of reactive oxygen species.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009;92(3):411-6.
2009: Barry Jutten; Ludwig Dubois; Younan Li; Hugo Aerts; Bradly G Wouters; Philippe Lambin; Jan Theys; Guido Lammering
Binding of cetuximab to the EGFRvIII deletion mutant and its biological consequences in malignant glioma cells.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009;92(3):393-8.
2009: Ludwig Dubois; Natasja Lieuwes; Alfonso Maresca; Anne Thiry; Claudiu T Supuran; Andrea Scozzafava; Bradly G Wouters; Philippe Lambin
Imaging of CA IX with fluorescent labelled sulfonamides distinguishes hypoxic and (re)-oxygenated cells in a xenograft tumour model.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009;92(3):423-8.
2009: Jan Theys; Barry Jutten; Ludwig Dubois; Kasper M A Rouschop; Roland K Chiu; Younan Li; Kim Paesmans; Philippe Lambin; Guido Lammering; Bradly G Wouters
The deletion mutant EGFRvIII significantly contributes to stress resistance typical for the tumour microenvironment.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009;92(3):399-404.
2009: Maud H W Starmans; Daniel Zips; Bradly G Wouters; Michael Baumann; Philippe Lambin
The use of a comprehensive tumour xenograft dataset to validate gene signatures relevant for radiation response.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009;92(3):417-22.
2009: Hugo Aerts; Angela van Baardwijk; Steven F Petit; Claudia Offermann; Judith van Loon; Ruud M A Houben; Anne-Marie C Dingemans; Rinus Wanders; Liesbeth J Boersma; Jacques Borger; Gerben Bootsma; Wiel Geraedts; Cordula Pitz; Jean Simons; Bradly G Wouters; Michel Oellers; Philippe Lambin; Geert Bosmans; André L A J Dekker; Dirk De Ruysscher
Identification of residual metabolic-active areas within individual NSCLC tumours using a pre-radiotherapy (18)Fluorodeoxyglucose-PET-CT scan.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009;91(3):386-92.
2009: Steven F Petit; Hugo Aerts; Judith G M van Loon; Claudia Offermann; Ruud M A Houben; Bjorn Winkens; Michel C Ollers; Philippe Lambin; Dirk De Ruysscher; André L A J Dekker
Metabolic control probability in tumour subvolumes or how to guide tumour dose redistribution in non-small cell lung cancer (NSCLC): an exploratory clinical study.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009;91(3):393-8.
2009: Madelon Pijls-Johannesma; Ruud M A Houben; Liesbeth J Boersma; Janneke Grutters; Katarina Seghers; Philippe Lambin; Rinus Wanders; Dirk De Ruysscher
High-dose radiotherapy or concurrent chemo-radiation in lung cancer patients only induces a temporary, reversible decline in QoL.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009;91(3):443-8.
2009: Dirk De Ruysscher; Ans Houben; Hugo Aerts; Cary Dehing; Rinus Wanders; Michel Ollers; Anne-Marie C Dingemans; Monique Hochstenbag; Liesbeth J Boersma; Jacques Borger; Andre Dekker; Philippe Lambin
Increased (18)F-deoxyglucose uptake in the lung during the first weeks of radiotherapy is correlated with subsequent Radiation-Induced Lung Toxicity (RILT): a prospective pilot study.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009;91(3):415-20.
2009: Cary Dehing-Oberije; Dirk De Ruysscher; Angela van Baardwijk; Shipeng Yu; Bharat Rao; Philippe Lambin
The importance of patient characteristics for the prediction of radiation-induced lung toxicity.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009;91(3):421-6.
2009: Cary Dehing-Oberije; Shipeng Yu; Dirk De Ruysscher; Sabine Meersschout; Karen Van Beek; Yolande Lievens; Jan Van Meerbeeck; Wilfried De Neve; Bharat Rao; Hiska van der Weide; Philippe Lambin
Development and external validation of prognostic model for 2-year survival of non-small-cell lung cancer patients treated with chemoradiotherapy.
International journal of radiation oncology, biology, physics 2009;74(2):355-62.
2009: Dirk De Ruysscher; Cary Dehing; Shipeng Yu; Rinus Wanders; Michel Ollers; Anne-Marie C Dingemans; Gerben Bootsma; Monique Hochstenbag; Wiel Geraedts; Cordula Pitz; Jean Simons; Liesbeth J Boersma; Jacques Borger; Andre Dekker; Philippe Lambin
Dyspnea evolution after high-dose radiotherapy in patients with non-small cell lung cancer.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009;91(3):353-9.
2009: Steven F Petit; André L A J Dekker; Renaud Seigneuric; Lars Murrer; Natal A W van Riel; Marianne Nordsmark; Jens Overgaard; Philippe Lambin; Bradly G Wouters
Intra-voxel heterogeneity influences the dose prescription for dose-painting with radiotherapy: a modelling study.
Physics in medicine and biology 2009;54(7):2179-96.
2009: Peter Ebbesen; Erik O Pettersen; Thomas A Gorr; Gerhard Jobst; Kaye Williams; Jochen Kieninger; Roland H Wenger; Silvia Pastorekova; Ludwig Dubois; Philippe Lambin; Brad G Wouters; Twan van den Beucken; Claudiu T Supuran; Lorenz Poellinger; Peter Ratcliffe; Arvydas Kanopka; Agnes Görlach; Max Gasmann; Adrian L Harris; Patrick Maxwell; Andrea Scozzafava
Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategies.
Journal of enzyme inhibition and medicinal chemistry 2009;24 Suppl 1():1-39.
2009: Wouter van Elmpt; S M J J G Nijsten; Steven Petit; Ben J Mijnheer; Philippe Lambin; André Dekker
3D in vivo dosimetry using megavoltage cone-beam CT and EPID dosimetry.
International journal of radiation oncology, biology, physics 2009;73(5):1580-7.
2009: Ludwig Dubois; Michaël G Magagnin; Arjen H G Cleven; Sherry A Weppler; Beat Grenacher; Willy Landuyt; Natasja Lieuwes; Philippe Lambin; Thomas A Gorr; Marianne Koritzinsky; Bradly G Wouters
Inhibition of 4E-BP1 sensitizes U87 glioblastoma xenograft tumors to irradiation by decreasing hypoxia tolerance.
International journal of radiation oncology, biology, physics 2009;73(4):1219-27.
2009: Judith van Loon; Janneke Grutters; Rinus Wanders; Liesbeth J Boersma; Michel Oellers; Anne-Marie Dingemans; Gerben Bootsma; Wiel Geraedts; Cordula Pitz; Jean Simons; Sakar Abdul Fatah; Gabriel Snoep; Monique Hochstenbag; Philippe Lambin; Dirk De Ruysscher
Follow-up with 18FDG-PET-CT after radical radiotherapy with or without chemotherapy allows the detection of potentially curable progressive disease in non-small cell lung cancer patients: a prospective study.
European journal of cancer (Oxford, England : 1990) 2009;45(4):588-95.
2009: Marco H M Janssen; Hugo Aerts; Michel Ollers; Geert Bosmans; John A Lee; Jeroen Buijsen; Dirk De Ruysscher; Philippe Lambin; Guido Lammering; André L A J Dekker
Tumor delineation based on time-activity curve differences assessed with dynamic fluorodeoxyglucose positron emission tomography-computed tomography in rectal cancer patients.
International journal of radiation oncology, biology, physics 2009;73(2):456-65.
2009: Danielle F M De Haas-Kock; Jeroen Buijsen; Madelon Pijls-Johannesma; Ludy Lutgens; Guido Lammering; Ghislaine A P G van Mastrigt; Dirk K M De Ruysscher; Philippe Lambin; Jacoba van der Zee
Concomitant hyperthermia and radiation therapy for treating locally advanced rectal cancer.
Cochrane database of systematic reviews (Online) 2009;(3):CD006269.
2009: Philippe Lambin; Bram Ramaekers; Ghislaine A P G van Mastrigt; P Van den Ende; J de Jong; Dirk K M De Ruysscher; Madelon Pijls-Johannesma
Erythropoietin as an adjuvant treatment with (chemo) radiation therapy for head and neck cancer.
Cochrane database of systematic reviews (Online) 2009;(3):CD006158.
2009: S M J J G Nijsten; Wouter J C van Elmpt; Ben J Mijnheer; A W H Minken; L C G G Persoon; Philippe Lambin; André L A J Dekker
Prediction of DVH parameter changes due to setup errors for breast cancer treatment based on 2D portal dosimetry.
Medical physics 2009;36(1):83-94.
2009: Hugo Aerts; Ludwig Dubois; Lars Perk; Peter Vermaelen; Guus A M S van Dongen; Bradly G Wouters; Philippe Lambin
Disparity between in vivo EGFR expression and 89Zr-labeled cetuximab uptake assessed with PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(1):123-31.
2009: D De Ruysscher; A Botterweck; M Dirx; Madelon Pijls-Johannesma; Rinus Wanders; Monique Hochstenbag; A-M C Dingemans; G Bootsma; W Geraedts; Jean Simons; C Pitz; Philippe Lambin
Eligibility for concurrent chemotherapy and radiotherapy of locally advanced lung cancer patients: a prospective, population-based study.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2009;20(1):98-102.
2008: M H W Starmans; Balaji Krishnapuram; H Steck; H Horlings; Dimitry S A Nuyten; Marc J van de Vijver; Renaud Seigneuric; F M Buffa; A L Harris; Bradly G Wouters; Philippe Lambin
Robust prognostic value of a knowledge-based proliferation signature across large patient microarray studies spanning different cancer types.
British journal of cancer 2008;99(11):1884-90.
2008: Wouter van Elmpt; Leah McDermott; S M J J G Nijsten; Markus Wendling; Philippe Lambin; Ben J Mijnheer
A literature review of electronic portal imaging for radiotherapy dosimetry.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2008;88(3):289-309.
2008: Wouter van Elmpt; Michel Ollers; Marije Velders; Kim Poels; Ben J Mijnheer; Dirk De Ruysscher; André Dekker; Philippe Lambin; Liesbeth J Boersma
Transition from a simple to a more advanced dose calculation algorithm for radiotherapy of non-small cell lung cancer (NSCLC): implications for clinical implementation in an individualized dose-escalation protocol.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2008;88(3):326-34.
2008: Angela van Baardwijk; Geert Bosmans; Liesbeth J Boersma; Stofferinus Wanders; André Dekker; Anne Marie C Dingemans; Gerben Bootsma; Wiel Geraedts; Cordula Pitz; Jean Simons; Philippe Lambin; Dirk De Ruysscher
Individualized radical radiotherapy of non-small-cell lung cancer based on normal tissue dose constraints: a feasibility study.
International journal of radiation oncology, biology, physics 2008;71(5):1394-401.
2008: Hugo Aerts; Geert Bosmans; Angela van Baardwijk; André L A J Dekker; Michel C Oellers; Philippe Lambin; Dirk De Ruysscher
Stability of 18F-deoxyglucose uptake locations within tumor during radiotherapy for NSCLC: a prospective study.
International journal of radiation oncology, biology, physics 2008;71(5):1402-7.
2008: Angela van Baardwijk; Geert Bosmans; Søren M Bentzen; Liesbeth J Boersma; André Dekker; Rinus Wanders; Bradly G Wouters; Philippe Lambin; Dirk De Ruysscher
Radiation dose prescription for non-small-cell lung cancer according to normal tissue dose constraints: an in silico clinical trial.
International journal of radiation oncology, biology, physics 2008;71(4):1103-10.
2008: Daniëlle Berty Petra Eekers; Andrea Laschet; Monique de Groot; Erik Roelofs; Arnold Kester; Karl Delaere; Philippe Lambin; Francis van Gils; Marius Nap; Joop ten Kate
Why determine only the total prostate-specific antigen, if the free-to-total ratio contains the information?
Annals of clinical biochemistry 2008;45(Pt 3):270-4.
2008: Madelon Pijls-Johannesma; Janneke P C Grutters; Philippe Lambin; Dirk De Ruysscher
Particle therapy in lung cancer: where do we stand?
Cancer treatment reviews 2008;34(3):259-67.
2008: Dirk De Ruysscher; Rinus Wanders; Erik van Haren; Monique Hochstenbag; Wiel Geraedts; Cordula Pitz; Jean Simons; Liesbeth J Boersma; Tom Verschueren; Andre Minken; Søren M Bentzen; Philippe Lambin
HI-CHART: a phase I/II study on the feasibility of high-dose continuous hyperfractionated accelerated radiotherapy in patients with inoperable non-small-cell lung cancer.
International journal of radiation oncology, biology, physics 2008;71(1):132-8.
2008: Geert Bosmans; Angela van Baardwijk; André Dekker; Michel Ollers; Stofferinus Wanders; Liesbeth J Boersma; Philippe Lambin; Dirk De Ruysscher
Time trends in nodal volumes and motion during radiotherapy for patients with stage III non-small-cell lung cancer.
International journal of radiation oncology, biology, physics 2008;71(1):139-44.
2008: Judith van Loon; Claudia Offermann; Geert Bosmans; Rinus Wanders; André Dekker; Jacques H Borger; Michel Oellers; Anne-Marie Dingemans; Angela van Baardwijk; Jaap Teule; Gabriel Snoep; Monique Hochstenbag; Ruud Houben; Philippe Lambin; Dirk De Ruysscher
18FDG-PET based radiation planning of mediastinal lymph nodes in limited disease small cell lung cancer changes radiotherapy fields: a planning study.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2008;87(1):49-54.
2008: Angela van Baardwijk; Geert Bosmans; Robert J van Suylen; Marinus Van Kroonenburgh; Monique Hochstenbag; Gijs Geskes; Philippe Lambin; Dirk De Ruysscher
Correlation of intra-tumour heterogeneity on 18F-FDG PET with pathologic features in non-small cell lung cancer: a feasibility study.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2008;87(1):55-8.
2008: Michel Ollers; Geert Bosmans; Angela van Baardwijk; André Dekker; Philippe Lambin; Jaap Teule; Willie Thimister; Ali Rhamy; Dirk De Ruysscher
The integration of PET-CT scans from different hospitals into radiotherapy treatment planning.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2008;87(1):142-6.
2008: Cary Dehing-Oberije; Dirk De Ruysscher; Hiska van der Weide; Monique Hochstenbag; Gerben Bootsma; Wiel Geraedts; Cordula Pitz; Jean Simons; Jaap Teule; Ali Rahmy; Paul Thimister; Harald Steck; Philippe Lambin
Tumor volume combined with number of positive lymph node stations is a more important prognostic factor than TNM stage for survival of non-small-cell lung cancer patients treated with (chemo)radiotherapy.
International journal of radiation oncology, biology, physics 2008;70(4):1039-44.
2008: Steven F Petit; Wouter J C van Elmpt; S M J J G Nijsten; Philippe Lambin; André L A J Dekker
Calibration of megavoltage cone-beam CT for radiotherapy dose calculations: correction of cupping artifacts and conversion of CT numbers to electron density.
Medical physics 2008;35(3):849-65.
2008: Michaël G Magagnin; Twan van den Beucken; kjell sergeant; Philippe Lambin; Marianne Koritzinsky; Bart Devreese; Bradly G Wouters
The mTOR target 4E-BP1 contributes to differential protein expression during normoxia and hypoxia through changes in mRNA translation efficiency.
Proteomics 2008;8(5):1019-28.
2008: Wouter van Elmpt; S M J J G Nijsten; Ben J Mijnheer; André Dekker; Philippe Lambin
The next step in patient-specific QA: 3D dose verification of conformal and intensity-modulated RT based on EPID dosimetry and Monte Carlo dose calculations.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2008;86(1):86-92.
2007: Esther J Bloemen-van Gurp; Ben J Mijnheer; Tom Verschueren; Philippe Lambin
Total body irradiation, toward optimal individual delivery: dose evaluation with metal oxide field effect transistors, thermoluminescence detectors, and a treatment planning system.
International journal of radiation oncology, biology, physics 2007;69(4):1297-304.
2007: Jonathan Orban de Xivry; Guillaume Janssens; Geert Bosmans; Mathieu De Craene; André Dekker; Jeroen Buijsen; Angela van Baardwijk; Dirk De Ruysscher; Benoît Macq; Philippe Lambin
Tumour delineation and cumulative dose computation in radiotherapy based on deformable registration of respiratory correlated CT images of lung cancer patients.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2007;85(2):232-8.
2007: S M J J G Nijsten; Wouter J C van Elmpt; M Jacobs; Ben J Mijnheer; André L A J Dekker; Philippe Lambin; Andre Minken
A global calibration model for a-Si EPIDs used for transit dosimetry.
Medical physics 2007;34(10):3872-84.
2007: Madelon Pijls-Johannesma; Dirk De Ruysscher; Johan Vansteenkiste; Arnold Kester; Isabelle Rutten; Philippe Lambin
Timing of chest radiotherapy in patients with limited stage small cell lung cancer: a systematic review and meta-analysis of randomised controlled trials.
Cancer treatment reviews 2007;33(5):461-73.
2007: Wouter J C van Elmpt; S M J J G Nijsten; André L A J Dekker; Ben J Mijnheer; Philippe Lambin
Treatment verification in the presence of inhomogeneities using EPID-based three-dimensional dose reconstruction.
Medical physics 2007;34(7):2816-26.
2007: Angela van Baardwijk; Geert Bosmans; Liesbeth J Boersma; Jeroen Buijsen; Stofferinus Wanders; Monique Hochstenbag; Robert J van Suylen; André Dekker; Cary Dehing-Oberije; Ruud Houben; Søren M Bentzen; Marinus Van Kroonenburgh; Philippe Lambin; Dirk De Ruysscher
PET-CT-based auto-contouring in non-small-cell lung cancer correlates with pathology and reduces interobserver variability in the delineation of the primary tumor and involved nodal volumes.
International journal of radiation oncology, biology, physics 2007;68(3):771-8.
2007: Ludy C H W Lutgens; Philippe Lambin
Biomarkers for radiation-induced small bowel epithelial damage: an emerging role for plasma Citrulline.
World journal of gastroenterology : WJG 2007;13(22):3033-42.
2007: Renaud Seigneuric; Maud H W Starmans; Glenn Fung; Balaji Krishnapuram; Dimitry S A Nuyten; Arie van Erk; Michaël G Magagnin; Kasper M A Rouschop; Sriram Krishnan; R Bharat Rao; Chris T A Evelo; Adrian C Begg; Bradly G Wouters; Philippe Lambin
Impact of supervised gene signatures of early hypoxia on patient survival.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2007;83(3):374-82.
2007: Michaël G Magagnin; kjell sergeant; Twan van den Beucken; Kasper M A Rouschop; Barry Jutten; Renaud Seigneuric; Philippe Lambin; Bart Devreese; Marianne Koritzinsky; Bradly G Wouters
Proteomic analysis of gene expression following hypoxia and reoxygenation reveals proteins involved in the recovery from endoplasmic reticulum and oxidative stress.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2007;83(3):340-5.
2007: Marianne Koritzinsky; Kasper M A Rouschop; Twan van den Beucken; Michaël G Magagnin; Kim Savelkouls; Philippe Lambin; Bradly G Wouters
Phosphorylation of eIF2alpha is required for mRNA translation inhibition and survival during moderate hypoxia.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2007;83(3):353-61.
2007: Hugo Aerts; Ludwig Dubois; Tilman M Hackeng; Roel Straathof; Roland K Chiu; Natasja Lieuwes; Barry Jutten; Sherry A Weppler; Guido Lammering; Bradly G Wouters; Philippe Lambin
Development and evaluation of a cetuximab-based imaging probe to target EGFR and EGFRvIII.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2007;83(3):326-32.
2007: Angela van Baardwijk; Christophe Dooms; Robert J van Suylen; Erik Verbeken; Monique Hochstenbag; Cary Dehing-Oberije; Dennis Rupa; Silvia Pastorekova; Sigrid Stroobants; Udalrich Buell; Philippe Lambin; Johan Vansteenkiste; Dirk De Ruysscher
The maximum uptake of (18)F-deoxyglucose on positron emission tomography scan correlates with survival, hypoxia inducible factor-1alpha and GLUT-1 in non-small cell lung cancer.
European journal of cancer (Oxford, England : 1990) 2007;43(9):1392-8.
2007: Sherry A Weppler; Younan Li; Ludwig Dubois; Natasja Lieuwes; Barry Jutten; Philippe Lambin; Bradly G Wouters; Guido Lammering
Expression of EGFR variant vIII promotes both radiation resistance and hypoxia tolerance.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2007;83(3):333-9.
2007: Ludwig Dubois; Kim Douma; Claudiu T Supuran; Roland K Chiu; Marc A M J van Zandvoort; Silvia Pastoreková; Andrea Scozzafava; Bradly G Wouters; Philippe Lambin
Imaging the hypoxia surrogate marker CA IX requires expression and catalytic activity for binding fluorescent sulfonamide inhibitors.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2007;83(3):367-73.
2007: Twan van den Beucken; Michaël G Magagnin; Kim Savelkouls; Philippe Lambin; Marianne Koritzinsky; Bradly G Wouters
Regulation of Cited2 expression provides a functional link between translational and transcriptional responses during hypoxia.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2007;83(3):346-52.
2007: Sabine A S Langie; Ad M Knaapen; Chantal H M A Ramaekers; Jan Theys; Jan Brun; Roger Godschalk; Frederik J Van Schooten; Philippe Lambin; Douglas A Gray; Bradly G Wouters; Roland K Chiu
Formation of lysine 63-linked poly-ubiquitin chains protects human lung cells against benzo[a]pyrene-diol-epoxide-induced mutagenicity.
DNA repair 2007;6(6):852-62.
2007: Pieter C Dagnelie; Madelon Pijls-Johannesma; Philippe Lambin; Sandra Beijer; Dirk De Ruysscher; Gertrudis I J M Kempen
Impact of fatigue on overall quality of life in lung and breast cancer patients selected for high-dose radiotherapy.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2007;18(5):940-4.
2007: Dirk De Ruysscher; Cary Dehing; R-H Bremer; Søren M Bentzen; F Koppe; Madelon Pijls-Johannesma; L Harzée; Andre Minken; Rinus Wanders; Monique Hochstenbag; A-M Dingemans; Liesbeth J Boersma; Erik van Haren; W Geraedts; C Pitz; Jean Simons; Bradly G Wouters; J-F Rosier; Philippe Lambin
Maximal neutropenia during chemotherapy and radiotherapy is significantly associated with the development of acute radiation-induced dysphagia in lung cancer patients.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2007;18(5):909-16.
2007: S M J J G Nijsten; Ben J Mijnheer; André L A J Dekker; Philippe Lambin; Andre Minken
Routine individualised patient dosimetry using electronic portal imaging devices.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2007;83(1):65-75.
2007: Ludwig Dubois; Tom Dresselaers; Willy Landuyt; K Paesmans; Asferd Mengesha; Bradly G Wouters; Paul Van Hecke; Jan Theys; Philippe Lambin
Efficacy of gene therapy-delivered cytosine deaminase is determined by enzymatic activity but not expression.
British journal of cancer 2007;96(5):758-61.
2007: M L Kimman; Adri C Voogd; C D Dirksen; P Falger; Pierre Hupperets; K Keymeulen; M Hebly; Cary Dehing; Philippe Lambin; Liesbeth J Boersma
Follow-up after curative treatment for breast cancer: why do we still adhere to frequent outpatient clinic visits?
European journal of cancer (Oxford, England : 1990) 2007;43(4):647-53.
2007: Jeroen Buijsen; Jos J Jager; Janneke Bovendeerd; Robert Voncken; Jacques H Borger; Liesbeth J Boersma; Lars H P Murrer; Philippe Lambin
Prone breast irradiation for pendulous breasts.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2007;82(3):337-40.
2007: Angela van Baardwijk; Geert Bosmans; André Dekker; Marinus Van Kroonenburgh; Liesbeth J Boersma; Stofferinus Wanders; Michel Ollers; Ruud Houben; Andre Minken; Philippe Lambin; Dirk De Ruysscher
Time trends in the maximal uptake of FDG on PET scan during thoracic radiotherapy. A prospective study in locally advanced non-small cell lung cancer (NSCLC) patients.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2007;82(2):145-52.
2007: Asferd Mengesha; Ludwig Dubois; Roland K Chiu; Kim Paesmans; Bradly G Wouters; Philippe Lambin; Jan Theys
Potential and limitations of bacterial-mediated cancer therapy.
Frontiers in bioscience : a journal and virtual library 2007;12():3880-91.
2007: Merel L Kimman; Adri C Voogd; Carmen D Dirksen; Paul Falger; Pierre Hupperets; Kristien Keymeulen; Marlene Hebly; Cary Dehing; Philippe Lambin; Liesbeth J Boersma
Improving the quality and efficiency of follow-up after curative treatment for breast cancer--rationale and study design of the MaCare trial.
BMC cancer 2007;7():1.
2007: Sherry A Weppler; Mechthild Krause; Agnieszka Zyromska; Philippe Lambin; Michael Baumann; Bradly G Wouters
Response of U87 glioma xenografts treated with concurrent rapamycin and fractionated radiotherapy: possible role for thrombosis.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2007;82(1):96-104.
2007: Veronique E M Mul; Adrienne J van Geest; Madelon Pijls-Johannesma; Jan Theys; Tom Verschueren; Jos J Jager; Philippe Lambin; Brigitta Baumert
Radiation-induced bullous pemphigoid: a systematic review of an unusual radiation side effect.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2007;82(1):5-9.
2006: Jan Theys; O Pennington; Ludwig Dubois; Gill M Anlezark; T Vaughan; Asferd Mengesha; Willy Landuyt; Jozef Anne; P J Burke; P Dûrre; Bradly G Wouters; Nigel P Minton; Philippe Lambin
Repeated cycles of Clostridium-directed enzyme prodrug therapy result in sustained antitumour effects in vivo.
British journal of cancer 2006;95(9):1212-9.
2006: Madelon Pijls-Johannesma; Dirk De Ruysscher; André L A J Dekker; Philippe Lambin
[Protons and ions in the treatment of cancer; a systematic review of the literature].
Nederlands tijdschrift voor geneeskunde 2006;150(44):2435-41.
2006: Geert Bosmans; Angela van Baardwijk; André Dekker; Michel Ollers; Liesbeth J Boersma; Andre Minken; Philippe Lambin; Dirk De Ruysscher
Intra-patient variability of tumor volume and tumor motion during conventionally fractionated radiotherapy for locally advanced non-small-cell lung cancer: a prospective clinical study.
International journal of radiation oncology, biology, physics 2006;66(3):748-53.
2006: Geert Bosmans; Jeroen Buijsen; André Dekker; Marije Velders; Liesbeth J Boersma; Dirk De Ruysscher; Andre Minken; Philippe Lambin
An "in silico" clinical trial comparing free breathing, slow and respiration correlated computed tomography in lung cancer patients.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2006;81(1):73-80.
2006: Dirk De Ruysscher; Robert-Harm Bremer; Friederike Koppe; Stofferinus Wanders; Erik van Haren; Monique Hochstenbag; Wiel Geeraedts; Cordula Pitz; Jean Simons; Guul P M ten Velde; Jo Dohmen; Gabriel Snoep; Liesbeth J Boersma; Tom Verschueren; Angela van Baardwijk; Cary Dehing; Madelon Pijls-Johannesma; Andre Minken; Philippe Lambin
Omission of elective node irradiation on basis of CT-scans in patients with limited disease small cell lung cancer: a phase II trial.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2006;80(3):307-12.
2006: Esther J Bloemen-van Gurp; Andre Minken; Ben J Mijnheer; Cary J G Dehing-Oberye; Philippe Lambin
Clinical implementation of MOSFET detectors for dosimetry in electron beams.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2006;80(3):288-95.
2006: Asferd Mengesha; Ludwig Dubois; Philippe Lambin; Willy Landuyt; Roland K Chiu; Bradly G Wouters; Jan Theys
Development of a flexible and potent hypoxia-inducible promoter for tumor-targeted gene expression in attenuated Salmonella.
Cancer biology & therapy 2006;5(9):1120-8.
2006: Brigitta Baumert; Isabelle Rutten; Cary Dehing-Oberije; Albert Twijnstra; Miranda J M Dirx; Ria M T L Debougnoux-Huppertz; Philippe Lambin; Bela Kubat
A pathology-based substrate for target definition in radiosurgery of brain metastases.
International journal of radiation oncology, biology, physics 2006;66(1):187-94.
2006: Wouter J C van Elmpt; S M J J G Nijsten; Robert F H Schiffeleers; André L A J Dekker; Ben J Mijnheer; Philippe Lambin; Andre Minken
A Monte Carlo based three-dimensional dose reconstruction method derived from portal dose images.
Medical physics 2006;33(7):2426-34.
2006: Roland K Chiu; Jan Brun; Chantal Ramaekers; Jan Theys; Lin Weng; Philippe Lambin; Douglas A Gray; Bradly G Wouters
Lysine 63-polyubiquitination guards against translesion synthesis-induced mutations.
PLoS genetics 2006;2(7):e116.
2006: C C A Nagel; Geert Bosmans; André L A J Dekker; Michel Ollers; Dirk De Ruysscher; Philippe Lambin; Andre Minken; N Lang; K P Schäfers
Phased attenuation correction in respiration correlated computed tomography/positron emitted tomography.
Medical physics 2006;33(6):1840-7.
2006: Cindy Duisters; Hilde Beurskens; S M J J G Nijsten; Maud Starmans; Stofferinus Wanders; Tom Verschueren; Philippe Lambin; Andre Minken; Dirk De Ruysscher
Palliative chest irradiation in sitting position in patients with bulky advanced lung cancer.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2006;79(3):285-7.
2006: Pieter C Dagnelie; Madelon Pijls-Johannesma; Anouk Pijpe; Brigit J E Boumans; Arno T P Skrabanja; Philippe Lambin; Gertrudis I J M Kempen
Psychometric properties of the revised Piper Fatigue Scale in Dutch cancer patients were satisfactory.
Journal of clinical epidemiology 2006;59(6):642-9.
2006: Angela van Baardwijk; Brigitta Baumert; Geert Bosmans; Marinus Van Kroonenburgh; Sigrid Stroobants; Vincent Gregoire; Philippe Lambin; Dirk De Ruysscher
The current status of FDG-PET in tumour volume definition in radiotherapy treatment planning.
Cancer treatment reviews 2006;32(4):245-60.
2006: Dirk De Ruysscher; Madelon Pijls-Johannesma; Johan Vansteenkiste; A Kester; Isabelle Rutten; Philippe Lambin
Systematic review and meta-analysis of randomised, controlled trials of the timing of chest radiotherapy in patients with limited-stage, small-cell lung cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2006;17(4):543-52.
2006: Marianne Koritzinsky; Michaël G Magagnin; Twan van den Beucken; Renaud Seigneuric; Kim Savelkouls; Josée Dostie; Stéphane Pyronnet; Randal J Kaufman; Sherry A Weppler; Jan Willem Voncken; Philippe Lambin; Constantinos Koumenis; Nahum Sonenberg; Bradly G Wouters
Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control.
The EMBO journal 2006;25(5):1114-25.
2006: Dirk De Ruysscher; Madelon Pijls-Johannesma; Søren M Bentzen; Andre Minken; Rinus Wanders; Ludy C H W Lutgens; Monique Hochstenbag; Liesbeth J Boersma; Bradly G Wouters; Guido Lammering; Johan Vansteenkiste; Philippe Lambin
Time between the first day of chemotherapy and the last day of chest radiation is the most important predictor of survival in limited-disease small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(7):1057-63.
2006: Angela van Baardwijk; Jos de Jong; Anne Arens; Paul Thimister; Gaico Verseput; Bernd Kremer; Philippe Lambin
False-positive FDG-PET scan due to brown tumours.
European journal of nuclear medicine and molecular imaging 2006;33(3):393-4.
2005: Quido G de Lussanet; Walter H Backes; Arjan W Griffioen; Anwar R Padhani; Coen I M Baeten; Angela van Baardwijk; Philippe Lambin; Geerard L Beets; Jos M A van Engelshoven; Regina G H Beets-Tan
Dynamic contrast-enhanced magnetic resonance imaging of radiation therapy-induced microcirculation changes in rectal cancer.
International journal of radiation oncology, biology, physics 2005;63(5):1309-15.
2005: Madelon Pijls-Johannesma; Anouk Pijpe; Gertrudis I J M Kempen; Philippe Lambin; Pieter C Dagnelie
Health related quality of life assessment instruments: a prospective study on preference and acceptability among cancer patients referred for radiotherapy.
European journal of cancer (Oxford, England : 1990) 2005;41(15):2250-6.
2005: Dirk De Ruysscher; Stofferinus Wanders; Andre Minken; Aniek Lumens; Jacqueline Schiffelers; Cissie Stultiens; Serve Halders; Liesbeth J Boersma; Angela van Baardwijk; Tom Verschueren; Monique Hochstenbag; Gabriel Snoep; Bradly G Wouters; S M J J G Nijsten; Søren M Bentzen; Marinus van Kroonenburgh; Michel Ollers; Philippe Lambin
Effects of radiotherapy planning with a dedicated combined PET-CT-simulator of patients with non-small cell lung cancer on dose limiting normal tissues and radiation dose-escalation: a planning study.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2005;77(1):5-10.
2005: Marianne Koritzinsky; Renaud Seigneuric; Michaël G Magagnin; Twan van den Beucken; Philippe Lambin; Bradly G Wouters
The hypoxic proteome is influenced by gene-specific changes in mRNA translation.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2005;76(2):177-86.
2005: Dirk De Ruysscher; Stofferinus Wanders; Erik van Haren; Monique Hochstenbag; Wiel Geeraedts; Irwan Utama; Jean Simons; Jo Dohmen; Ali Rhami; Udalrich Buell; Paul Thimister; Gabriel Snoep; Liesbeth J Boersma; Tom Verschueren; Angela van Baardwijk; Andre Minken; Søren M Bentzen; Philippe Lambin
Selective mediastinal node irradiation based on FDG-PET scan data in patients with non-small-cell lung cancer: a prospective clinical study.
International journal of radiation oncology, biology, physics 2005;62(4):988-94.
2005: Sofie Barbé; Lieve Van Mellaert; Jan Theys; Nick Geukens; Elke Lammertyn; Philippe Lambin; Jozef Anne
Secretory production of biologically active rat interleukin-2 by Clostridium acetobutylicum DSM792 as a tool for anti-tumor treatment.
FEMS microbiology letters 2005;246(1):67-73.
2005: Antoinet van Der Wel; S M J J G Nijsten; Monique Hochstenbag; Rob Lamers; Liesbeth J Boersma; Rinus Wanders; Ludy C H W Lutgens; Michael Zimny; Søren M Bentzen; Bradly G Wouters; Philippe Lambin; Dirk De Ruysscher
Increased therapeutic ratio by 18FDG-PET CT planning in patients with clinical CT stage N2-N3M0 non-small-cell lung cancer: a modeling study.
International journal of radiation oncology, biology, physics 2005;61(3):649-55.
2005: Ludy C H W Lutgens; N M A Blijlevens; Nicolaas E P Deutz; J Peter Donnelly; Philippe Lambin; Ben E de Pauw
Monitoring myeloablative therapy-induced small bowel toxicity by serum citrulline concentration: a comparison with sugar permeability tests.
Cancer 2005;103(1):191-9.
2004: barbara bussels; Alex Maes; Patrick Flamen; Philippe Lambin; Katrien Erven; Robert Hermans; Sandra Nuyts; Caroline Weltens; Silvia Cecere; Emmanuel Lesaffre; Walter Van den Bogaert
Dose-response relationships within the parotid gland after radiotherapy for head and neck cancer.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2004;73(3):297-306.
2004: Ludy C H W Lutgens; Nicolaas E P Deutz; Marlies Granzier-Peeters; Regina Beets-Tan; Dirk De Ruysscher; John Gueulette; Jack P M Cleutjens; Martijn Berger; Bradly G Wouters; Maarten F von Meyenfeldt; Philippe Lambin
Plasma citrulline concentration: a surrogate end point for radiation-induced mucosal atrophy of the small bowel. A feasibility study in 23 patients.
International journal of radiation oncology, biology, physics 2004;60(1):275-85.
2004: Bradly G Wouters; Twan van den Beucken; Michaël G Magagnin; Philippe Lambin; Constantinos Koumenis
Targeting hypoxia tolerance in cancer.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2004;7(1):25-40.
2004: S M J J G Nijsten; Andre Minken; Philippe Lambin; I A D Bruinvis
Verification of treatment parameter transfer by means of electronic portal dosimetry.
Medical physics 2004;31(2):341-7.
2003: Robert Hermans; Martijn Meijerink; Walter Van den Bogaert; Alexis Rijnders; Caroline Weltens; Philippe Lambin
Tumor perfusion rate determined noninvasively by dynamic computed tomography predicts outcome in head-and-neck cancer after radiotherapy.
International journal of radiation oncology, biology, physics 2003;57(5):1351-6.
2003: Ludy C H W Lutgens; Nicolaas E P Deutz; John Gueulette; Jack P M Cleutjens; Martijn P F Berger; Bradly G Wouters; Maarten F von Meyenfeldt; Philippe Lambin
Citrulline: a physiologic marker enabling quantitation and monitoring of epithelial radiation-induced small bowel damage.
International journal of radiation oncology, biology, physics 2003;57(4):1067-74.
2003: Tom Dresselaers; Jan Theys; Sandra Nuyts; Bradly G Wouters; Ernst A de Bruijn; Jozef Anne; Philippe Lambin; Paul Van Hecke; Willy Landuyt
Non-invasive 19F MR spectroscopy of 5-fluorocytosine to 5-fluorouracil conversion by recombinant Salmonella in tumours.
British journal of cancer 2003;89(9):1796-801.
2003: Jan Theys; Sofie Barbé; Willy Landuyt; Sandra Nuyts; Lieve Van Mellaert; Bradly G Wouters; Jozef Anne; Philippe Lambin
Tumor-specific gene delivery using genetically engineered bacteria.
Current gene therapy 2003;3(3):207-21.
2003: Bisan Ahmed; Loes I van Eijk; Jessica C A Bouma-Ter Steege; Daisy W J van der Schaft; Anita M Van Esch; Susan R Joosten-Achjanie; Philippe Lambin; Willy Landuyt; Arjan W Griffioen
Vascular targeting effect of combretastatin A-4 phosphate dominates the inherent angiogenesis inhibitory activity.
International journal of cancer. Journal international du cancer 2003;105(1):20-5.
2003: Bradly G Wouters; Marianne Koritzinsky; Roland K Chiu; Jan Theys; Jeroen Buijsen; Philippe Lambin
Modulation of cell death in the tumor microenvironment.
Seminars in radiation oncology 2003;13(1):31-41.
2002: Shaoping Mei; Jan Theys; Willy Landuyt; Jozef Anne; Philippe Lambin
Optimization of tumor-targeted gene delivery by engineered attenuated Salmonella typhimurium.
Anticancer research 2002;22(6A):3261-6.
2002: Karin Stellamans; Yolande Lievens; Philippe Lambin; Danielle Van den Weyngaert; Walter Van den Bogaert; Pierre Scalliet; Liesbeth Hutsebaut; Karin Haustermans
Does sucralfate reduce early side effects of pelvic radiation? A double-blind randomized trial.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2002;65(2):105-8.
2002: Willy Landuyt; Stefan Sunaert; Davide Farina; Martijn Meijerink; Eric Béatse; Paul Van Hecke; Robert Hermans; Guy Marchal; Philippe Lambin; Hilde Bosmans
In vivo animal functional MRI: improved image quality with a body-adapted mold.
Journal of magnetic resonance imaging : JMRI 2002;16(2):224-7.
2002: Alex Maes; Caroline Weltens; Patrick Flamen; Philippe Lambin; Ria Bogaerts; Xuan Liu; Jan Baetens; Robert Hermans; Walter Van den Bogaert
Preservation of parotid function with uncomplicated conformal radiotherapy.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2002;63(2):203-11.
2002: Sandra Nuyts; Lieve Van Mellaert; Jan Theys; Willy Landuyt; Philippe Lambin; Jozef Anne
Clostridium spores for tumor-specific drug delivery.
Anti-cancer drugs 2002;13(2):115-25.
2002: Bradly G Wouters; Sherry A Weppler; Marianne Koritzinsky; Willy Landuyt; Sandra Nuyts; Jan Theys; Roland K Chiu; Philippe Lambin
Hypoxia as a target for combined modality treatments.
European journal of cancer (Oxford, England : 1990) 2002;38(2):240-57.
2001: Sandra Nuyts; Lieve Van Mellaert; Sofie Barbé; Elke Lammertyn; Jan Theys; Willy Landuyt; Eugene Bosmans; Philippe Lambin; Jozef Anne
Insertion or deletion of the Cheo box modifies radiation inducibility of Clostridium promoters.
Applied and environmental microbiology 2001;67(10):4464-70.
2001: Sandra Nuyts; Lieve Van Mellaert; Jan Theys; Willy Landuyt; Eugene Bosmans; Jozef Anne; Philippe Lambin
Radio-responsive recA promoter significantly increases TNFalpha production in recombinant clostridia after 2 Gy irradiation.
Gene therapy 2001;8(15):1197-201.
2001: Sandra Nuyts; Lieve Van Mellaert; Jan Theys; Willy Landuyt; Philippe Lambin; Jozef Anne
The use of radiation-induced bacterial promoters in anaerobic conditions: a means to control gene expression in clostridium-mediated therapy for cancer.
Radiation research 2001;155(5):716-23.
2001: Jan Theys; Willy Landuyt; Sandra Nuyts; Lieve Van Mellaert; Allan van Oosterom; Philippe Lambin; Jozef Anne
Specific targeting of cytosine deaminase to solid tumors by engineered Clostridium acetobutylicum.
Cancer gene therapy 2001;8(4):294-7.
2001: Sandra Nuyts; Lieve Van Mellaert; Philippe Lambin; Jozef Anne
Efficient isolation of total RNA from Clostridium without DNA contamination.
Journal of microbiological methods 2001;44(3):235-8.
2001: Sandra Nuyts; Jan Theys; Willy Landuyt; Lieve Van Mellaert; Philippe Lambin; Jozef Anne
Increasing specificity of anti-tumor therapy: cytotoxic protein delivery by non-pathogenic clostridia under regulation of radio-induced promoters.
Anticancer research 2001;21(2A):857-61.
2001: Frank Van Acker; Patrick Flamen; Philippe Lambin; A Maes; Gerald J Kutcher; Caroline Weltens; Robert Hermans; J Baetens; Patrick Dupont; Alexis Rijnders; Alex Maes; Walter Van den Bogaert; Luc Mortelmans
The utility of SPECT in determining the relationship between radiation dose and salivary gland dysfunction after radiotherapy.
Nuclear medicine communications 2001;22(2):225-31.
2001: Willy Landuyt; Bisan Ahmed; Sandra Nuyts; Jan Theys; M Op de Beeck; Alexis Rijnders; Jozef Anne; Allan van Oosterom; Walter Van den Bogaert; Philippe Lambin
In vivo antitumor effect of vascular targeting combined with either ionizing radiation or anti-angiogenesis treatment.
International journal of radiation oncology, biology, physics 2001;49(2):443-50.
2001: Jan Theys; Willy Landuyt; Sandra Nuyts; Lieve Van Mellaert; Eugene Bosmans; Alexis Rijnders; Walter Van den Bogaert; Allan van Oosterom; Jozef Anne; Philippe Lambin
Improvement of Clostridium tumour targeting vectors evaluated in rat rhabdomyosarcomas.
FEMS immunology and medical microbiology 2001;30(1):37-41.
2001: Jan Theys; A W Landuyt; Sandra Nuyts; Lieve Van Mellaert; Philippe Lambin; Jozef Anne
Clostridium as a tumor-specific delivery system of therapeutic proteins.
Cancer detection and prevention 2001;25(6):548-57.
2001: Willy Landuyt; Robert Hermans; Hilde Bosmans; Stefan Sunaert; Erik Béatse; D Farina; Martijn Meijerink; H Zhang; Walter Van den Bogaert; Philippe Lambin; Guy Marchal
BOLD contrast fMRI of whole rodent tumour during air or carbogen breathing using echo-planar imaging at 1.5 T.
European radiology 2001;11(11):2332-40.
2001: Willy Landuyt; Jan Theys; Sandra Nuyts; Maria Drijkoningen; J Fowler; A Reijnders; Sandra Liekens; Johan Neyts; Ernst A de Bruijn; Jozef Anne; Philippe Lambin
Effect of TNP-470 (AGM-1470) on the growth of rat rhabdomyosarcoma tumors of different sizes.
Cancer investigation 2001;19(1):35-40.
2000: Philippe Lambin; Sandra Nuyts; Willy Landuyt; Jan Theys; Ernst A de Bruijn; Jozef Anne; Lieve Van Mellaert; J Fowler
The potential therapeutic gain of radiation-associated gene therapy with the suicide gene cytosine deaminase.
International journal of radiation biology 2000;76(3):285-93.
1999: Robert Hermans; Philippe Lambin; Ann Van Der Goten; Walter Van den Bogaert; B Verbist; Caroline Weltens; Pierre Delaere
Tumoural perfusion as measured by dynamic computed tomography in head and neck carcinoma.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1999;53(2):105-11.
1999: Jan Theys; Sandra Nuyts; Willy Landuyt; Lieve Van Mellaert; Chris Dillen; Michael Böhringer; Peter Dürre; Philippe Lambin; Jozef Anne
Stable Escherichia coli-Clostridium acetobutylicum shuttle vector for secretion of murine tumor necrosis factor alpha.
Applied and environmental microbiology 1999;65(10):4295-300.
1998: Philippe Lambin; Jan Theys; Willy Landuyt; P Rijken; AJ van der Kogel; E van der Schueren; R Hodgkiss; J Fowler; Sandra Nuyts; Ernst A de Bruijn; Lieve Van Mellaert; Jozef Anne
Colonisation of Clostridium in the body is restricted to hypoxic and necrotic areas of tumours.
Anaerobe 1998;4(4):183-8.
1998: Yolande Lievens; Karin Haustermans; Danielle Van den Weyngaert; Walter Van den Bogaert; Pierre Scalliet; L Hutsebaut; J Fowler; Philippe Lambin
Does sucralfate reduce the acute side-effects in head and neck cancer treated with radiotherapy? A double-blind randomized trial.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1998;47(2):149-53.
1997: Karin Haustermans; J Fowler; Willy Landuyt; Philippe Lambin; AJ van der Kogel; E van der Schueren
Is pulsed dose rate more damaging to spinal cord of rats than continuous low dose rate?
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1997;45(1):39-47.
1997: Robert Hermans; Philippe Lambin; Walter Van den Bogaert; Karin Haustermans; Ann Van Der Goten; AL Baert
Non-invasive tumour perfusion measurement by dynamic CT: preliminary results.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1997;44(2):159-62.
1997: Brian Marples; Philippe Lambin; K A Skov; Michael Charles Joiner
Low dose hyper-radiosensitivity and increased radioresistance in mammalian cells.
International journal of radiation biology 1997;71(6):721-35.