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Alan Lambowitz

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
15
Perlman, Philip
11
Akins, Robert
10
Mohr, Sabine
8
Del Campo, Mark
8
Zimmerly, Steven
6
Belfort, Marlene
6
Mohr, Georg
6
Perutka, Jiri
6
Nargang, Frank
5
Jankowsky, Eckhard
5
Zhong, Jin
4
Yang, Quansheng
4
Yao, Jun
4
San Filippo, Joseph
4
Paukstelis, Paul

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Publications

TOP 3
Zhuang Fanglei; Mastroianni Marta; White Travis B; Lambowitz Alan M
Linear group II intron RNAs can retrohome in eukaryotes and may use nonhomologous end-joining for cDNA ligation.
Del Campo Mark; Lambowitz Alan M
Structure of the Yeast DEAD box protein Mss116p reveals two wedges that crimp RNA.
Del Campo Mark; Lambowitz Alan M
Crystallization and preliminary X-ray diffraction of the DEAD-box protein Mss116p complexed with an RNA oligonucleotide and AMP-PNP.

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All Publications

2009: Zhuang Fanglei; Mastroianni Marta; White Travis B; Lambowitz Alan M
Linear group II intron RNAs can retrohome in eukaryotes and may use nonhomologous end-joining for cDNA ligation.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(43):18189-94.
2009: Del Campo Mark; Lambowitz Alan M
Structure of the Yeast DEAD box protein Mss116p reveals two wedges that crimp RNA.
Molecular cell 2009;35(5):598-609.
2009: Del Campo Mark; Lambowitz Alan M
Crystallization and preliminary X-ray diffraction of the DEAD-box protein Mss116p complexed with an RNA oligonucleotide and AMP-PNP.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 8):832-5.
2009: Markov Dmitriy A; Savkina Maria; Anikin Michael; Del Campo Mark; Ecker Karen; Lambowitz Alan M; De Gnore Jon P; McAllister William T
Identification of proteins associated with the yeast mitochondrial RNA polymerase by tandem affinity purification.
Yeast (Chichester, England) 2009;26(8):423-40.
2009: Del Campo Mark; Mohr Sabine; Jiang Yue; Jia Huijue; Jankowsky Eckhard; Lambowitz Alan M
Unwinding by local strand separation is critical for the function of DEAD-box proteins as RNA chaperones.
Journal of molecular biology 2009;389(4):674-93.
2009: Zhuang Fanglei; Karberg Michael; Perutka Jiri; Lambowitz Alan M
EcI5, a group IIB intron with high retrohoming frequency: DNA target site recognition and use in gene targeting.
RNA (New York, N.Y.) 2009;15(3):432-49.
2008: Vicens Quentin; Paukstelis Paul J; Westhof Eric; Lambowitz Alan M; Cech Thomas R
Toward predicting self-splicing and protein-facilitated splicing of group I introns.
RNA (New York, N.Y.) 2008;14(10):2013-29.
2008: Zhao Junhua; Niu Wei; Yao Jun; Mohr Sabine; Marcotte Edward M; Lambowitz Alan M
Group II intron protein localization and insertion sites are affected by polyphosphate.
PLoS biology 2008;6(6):e150.
2008: Dai Lixin; Chai Dinggeng; Gu Shan-Qing; Gabel Jesse; Noskov Sergei Y; Blocker Forrest J H; Lambowitz Alan M; Zimmerly Steven
A three-dimensional model of a group II intron RNA and its interaction with the intron-encoded reverse transcriptase.
Molecular cell 2008;30(4):472-85.
2008: Paukstelis Paul J; Lambowitz Alan M
Identification and evolution of fungal mitochondrial tyrosyl-tRNA synthetases with group I intron splicing activity.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(16):6010-5.
2008: Mohr Georg; Del Campo Mark; Mohr Sabine; Yang Quansheng; Jia Huijue; Jankowsky Eckhard; Lambowitz Alan M
Function of the C-terminal domain of the DEAD-box protein Mss116p analyzed in vivo and in vitro.
Journal of molecular biology 2008;375(5):1344-64.
2008: Paukstelis Paul J; Chen Jui-Hui; Chase Elaine; Lambowitz Alan M; Golden Barbara L
Structure of a tyrosyl-tRNA synthetase splicing factor bound to a group I intron RNA.
Nature 2008;451(7174):94-7.
2008: Mastroianni Marta; Watanabe Kazuo; White Travis B; Zhuang Fanglei; Vernon Jamie; Matsuura Manabu; Wallingford John; Lambowitz Alan M
Group II intron-based gene targeting reactions in eukaryotes.
PloS one 2008;3(9):e3121.
2007: Yang Quansheng; Del Campo Mark; Lambowitz Alan M; Jankowsky Eckhard
DEAD-box proteins unwind duplexes by local strand separation.
Molecular cell 2007;28(2):253-63.
2007: Del Campo Mark; Tijerina Pilar; Bhaskaran Hari; Mohr Sabine; Yang Quansheng; Jankowsky Eckhard; Russell Rick; Lambowitz Alan M
Do DEAD-box proteins promote group II intron splicing without unwinding RNA?
Molecular cell 2007;28(1):159-66.
2007: Yao Jun; Lambowitz Alan M
Gene targeting in gram-negative bacteria by use of a mobile group II intron ("Targetron") expressed from a broad-host-range vector.
Applied and environmental microbiology 2007;73(8):2735-43.
2007: Grohman Jacob K; Del Campo Mark; Bhaskaran Hari; Tijerina Pilar; Lambowitz Alan M; Russell Rick
Probing the mechanisms of DEAD-box proteins as general RNA chaperones: the C-terminal domain of CYT-19 mediates general recognition of RNA.
Biochemistry 2007;46(11):3013-22.
2007: Halls Coralie; Mohr Sabine; Del Campo Mark; Yang Quansheng; Jankowsky Eckhard; Lambowitz Alan M
Involvement of DEAD-box proteins in group I and group II intron splicing. Biochemical characterization of Mss116p, ATP hydrolysis-dependent and -independent mechanisms, and general RNA chaperone activity.
Journal of molecular biology 2007;365(3):835-55.
2006: Noah James W; Park Soyeun; Whitt Jacob T; Perutka Jiri; Frey Wolfgang; Lambowitz Alan M
Atomic force microscopy reveals DNA bending during group II intron ribonucleoprotein particle integration into double-stranded DNA.
Biochemistry 2006;45(41):12424-35.
2006: Yao Jun; Zhong Jin; Fang Yuan; Geisinger Edward; Novick Richard P; Lambowitz Alan M
Use of targetrons to disrupt essential and nonessential genes in Staphylococcus aureus reveals temperature sensitivity of Ll.LtrB group II intron splicing.
RNA (New York, N.Y.) 2006;12(7):1271-81.
2006: Mohr Sabine; Matsuura Manabu; Perlman Philip S; Lambowitz Alan M
A DEAD-box protein alone promotes group II intron splicing and reverse splicing by acting as an RNA chaperone.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(10):3569-74.
2005: Zhao Junhua; Lambowitz Alan M
Inaugural Article: A bacterial group II intron-encoded reverse transcriptase localizes to cellular poles.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(45):16133-40.
2005: Smith Dorie; Zhong Jin; Matsuura Manabu; Lambowitz Alan M; Belfort Marlene
Recruitment of host functions suggests a repair pathway for late steps in group II intron retrohoming.
Genes & development 2005;19(20):2477-87.
2005: Jones John Patrick; Kierlin Monique N; Coon Robert G; Perutka Jiri; Lambowitz Alan M; Sullenger Bruce A
Retargeting mobile group II introns to repair mutant genes.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(5):687-94.
2005: Coros Colin J; Landthaler Markus; Piazza Carol Lyn; Beauregard Arthur; Esposito Donna; Perutka Jiri; Lambowitz Alan M; Belfort Marlene
Retrotransposition strategies of the Lactococcus lactis Ll.LtrB group II intron are dictated by host identity and cellular environment.
Molecular microbiology 2005;56(2):509-24.
2005: Paukstelis Paul J; Coon Robert; Madabusi Lakshmi; Nowakowski Jacek; Monzingo Arthur; Robertus Jon; Lambowitz Alan M
A tyrosyl-tRNA synthetase adapted to function in group I intron splicing by acquiring a new RNA binding surface.
Molecular cell 2005;17(3):417-28.
2005: Huang Hon-Ren; Rowe Claire E; Mohr Sabine; Jiang Yue; Lambowitz Alan M; Perlman Philip S
The splicing of yeast mitochondrial group I and group II introns requires a DEAD-box protein with RNA chaperone function.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(1):163-8.
2005: Blocker Forrest J H; Mohr Georg; Conlan Lori H; Qi Li; Belfort Marlene; Lambowitz Alan M
Domain structure and three-dimensional model of a group II intron-encoded reverse transcriptase.
RNA (New York, N.Y.) 2005;11(1):14-28.
2005: Yao Jun; Zhong Jin; Lambowitz Alan M
Gene targeting using randomly inserted group II introns (targetrons) recovered from an Escherichia coli gene disruption library.
Nucleic acids research 2005;33(10):3351-62.
2004: Watanabe Kazuo; Lambowitz Alan M
High-affinity binding site for a group II intron-encoded reverse transcriptase/maturase within a stem-loop structure in the intron RNA.
RNA (New York, N.Y.) 2004;10(9):1433-43.
2004: Cui Xiaoxia; Matsuura Manabu; Wang Qin; Ma Hongwen; Lambowitz Alan M
A group II intron-encoded maturase functions preferentially in cis and requires both the reverse transcriptase and X domains to promote RNA splicing.
Journal of molecular biology 2004;340(2):211-31.
2004: Chen Xin; Mohr Georg; Lambowitz Alan M
The Neurospora crassa CYT-18 protein C-terminal RNA-binding domain helps stabilize interdomain tertiary interactions in group I introns.
RNA (New York, N.Y.) 2004;10(4):634-44.
2004: Perutka Jiri; Wang Wenjun; Goerlitz David; Lambowitz Alan M
Use of computer-designed group II introns to disrupt Escherichia coli DExH/D-box protein and DNA helicase genes.
Journal of molecular biology 2004;336(2):421-39.
2004: Lambowitz Alan M; Zimmerly Steven
Mobile group II introns.
Annual review of genetics 2004;38():1-35.
2003: Huang Hon-Ren; Chao Michael Y; Armstrong Barbara; Wang Yong; Lambowitz Alan M; Perlman Philip S
The DIVa maturase binding site in the yeast group II intron aI2 is essential for intron homing but not for in vivo splicing.
Molecular and cellular biology 2003;23(23):8809-19.
2003: Noah James W; Lambowitz Alan M
Effects of maturase binding and Mg2+ concentration on group II intron RNA folding investigated by UV cross-linking.
Biochemistry 2003;42(43):12466-80.
2003: Zhong Jin; Lambowitz Alan M
Group II intron mobility using nascent strands at DNA replication forks to prime reverse transcription.
The EMBO journal 2003;22(17):4555-65.
2003: Muñoz-Adelantado Estefanía; San Filippo Joseph; Martínez-Abarca Francisco; García-Rodríguez Fernando M; Lambowitz Alan M; Toro Nicolás
Mobility of the Sinorhizobium meliloti group II intron RmInt1 occurs by reverse splicing into DNA, but requires an unknown reverse transcriptase priming mechanism.
Journal of molecular biology 2003;327(5):931-43.
2003: Aizawa Yasunori; Xiang Qing; Lambowitz Alan M; Pyle Anna Marie
The pathway for DNA recognition and RNA integration by a group II intron retrotransposon.
Molecular cell 2003;11(3):795-805.
2003: Zhong Jin; Karberg Michael; Lambowitz Alan M
Targeted and random bacterial gene disruption using a group II intron (targetron) vector containing a retrotransposition-activated selectable marker.
Nucleic acids research 2003;31(6):1656-64.
2003: Frazier Courtney L; San Filippo Joseph; Lambowitz Alan M; Mills David A
Genetic manipulation of Lactococcus lactis by using targeted group II introns: generation of stable insertions without selection.
Applied and environmental microbiology 2003;69(2):1121-8.
2003: Mohr Georg; Lambowitz Alan M
Putative proteins related to group II intron reverse transcriptase/maturases are encoded by nuclear genes in higher plants.
Nucleic acids research 2003;31(2):647-52.
2002: San Filippo Joseph; Lambowitz Alan M
Characterization of the C-terminal DNA-binding/DNA endonuclease region of a group II intron-encoded protein.
Journal of molecular biology 2002;324(5):933-51.
2002: Mohr Sabine; Stryker John M; Lambowitz Alan M
A DEAD-box protein functions as an ATP-dependent RNA chaperone in group I intron splicing.
Cell 2002;109(6):769-79.
2002: Singh Ravindra N; Saldanha Roland J; D'Souza Lisa M; Lambowitz Alan M
Binding of a group II intron-encoded reverse transcriptase/maturase to its high affinity intron RNA binding site involves sequence-specific recognition and autoregulates translation.
Journal of molecular biology 2002;318(2):287-303.
2002: Myers Christopher A; Kuhla Birte; Cusack Stephen; Lambowitz Alan M
tRNA-like recognition of group I introns by a tyrosyl-tRNA synthetase.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):2630-5.
2001: Matsuura M; Noah J W; Lambowitz A M
Mechanism of maturase-promoted group II intron splicing.
The EMBO journal 2001;20(24):7259-70.
2001: Karberg M; Guo H; Zhong J; Coon R; Perutka J; Lambowitz A M
Group II introns as controllable gene targeting vectors for genetic manipulation of bacteria.
Nature biotechnology 2001;19(12):1162-7.
2001: Dickson L; Huang H R; Liu L; Matsuura M; Lambowitz A M; Perlman P S
Retrotransposition of a yeast group II intron occurs by reverse splicing directly into ectopic DNA sites.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(23):13207-12.
2001: Singh N N; Lambowitz A M
Interaction of a group II intron ribonucleoprotein endonuclease with its DNA target site investigated by DNA footprinting and modification interference.
Journal of molecular biology 2001;309(2):361-86.
2001: Caprara M G; Myers C A; Lambowitz A M
Interaction of the Neurospora crassa mitochondrial tyrosyl-tRNA synthetase (CYT-18 protein) with the group I intron P4-P6 domain. Thermodynamic analysis and the role of metal ions.
Journal of molecular biology 2001;308(2):165-90.
2001: Mohr G; Rennard R; Cherniack A D; Stryker J; Lambowitz A M
Function of the Neurospora crassa mitochondrial tyrosyl-tRNA synthetase in RNA splicing. Role of the idiosyncratic N-terminal extension and different modes of interaction with different group I introns.
Journal of molecular biology 2001;307(1):75-92.
2000: Eskes R; Liu L; Ma H; Chao M Y; Dickson L; Lambowitz A M; Perlman P S
Multiple homing pathways used by yeast mitochondrial group II introns.
Molecular and cellular biology 2000;20(22):8432-46.
2000: Chen X; Gutell R R; Lambowitz A M
Function of tyrosyl-tRNA synthetase in splicing group I introns: an induced-fit model for binding to the P4-P6 domain based on analysis of mutations at the junction of the P4-P6 stacked helices.
Journal of molecular biology 2000;301(2):265-83.
2000: Mohr S; Wanner L A; Bertrand H; Lambowitz A M
Characterization of an unusual tRNA-like sequence found inserted in a Neurospora retroplasmid.
Nucleic acids research 2000;28(13):1514-24.
2000: Guo H; Karberg M; Long M; Jones J P; Sullenger B; Lambowitz A M
Group II introns designed to insert into therapeutically relevant DNA target sites in human cells.
Science (New York, N.Y.) 2000;289(5478):452-7.
2000: Mohr S; Wanner L A; Bertrand H; Lambowitz A M
Characterization of an unusual tRNA-like sequence found inserted in a Neurospora retroplasmid.
Nucleic acids research 2000;28(7):1514-24.
2000: Mohr G; Smith D; Belfort M; Lambowitz A M
Rules for DNA target-site recognition by a lactococcal group II intron enable retargeting of the intron to specific DNA sequences.
Genes & development 2000;14(5):559-73.
1999: Wank H; SanFilippo J; Singh R N; Matsuura M; Lambowitz A M
A reverse transcriptase/maturase promotes splicing by binding at its own coding segment in a group II intron RNA.
Molecular cell 1999;4(2):239-50.
1999: Saldanha R; Chen B; Wank H; Matsuura M; Edwards J; Lambowitz A M
RNA and protein catalysis in group II intron splicing and mobility reactions using purified components.
Biochemistry 1999;38(28):9069-83.
1999: Zimmerly S; Moran J V; Perlman P S; Lambowitz A M
Group II intron reverse transcriptase in yeast mitochondria. Stabilization and regulation of reverse transcriptase activity by the intron RNA.
Journal of molecular biology 1999;289(3):473-90.
1998: Yang J; Mohr G; Perlman P S; Lambowitz A M
Group II intron mobility in yeast mitochondria: target DNA-primed reverse transcription activity of aI1 and reverse splicing into DNA transposition sites in vitro.
Journal of molecular biology 1998;282(3):505-23.
1998: Cousineau B; Smith D; Lawrence-Cavanagh S; Mueller J E; Yang J; Mills D; Manias D; Dunny G; Lambowitz A M; Belfort M
Retrohoming of a bacterial group II intron: mobility via complete reverse splicing, independent of homologous DNA recombination.
Cell 1998;94(4):451-62.
1997: Guo H; Zimmerly S; Perlman P S; Lambowitz A M
Group II intron endonucleases use both RNA and protein subunits for recognition of specific sequences in double-stranded DNA.
The EMBO journal 1997;16(22):6835-48.
1997: Matsuura M; Saldanha R; Ma H; Wank H; Yang J; Mohr G; Cavanagh S; Dunny G M; Belfort M; Lambowitz A M
A bacterial group II intron encoding reverse transcriptase, maturase, and DNA endonuclease activities: biochemical demonstration of maturase activity and insertion of new genetic information within the intron.
Genes & development 1997;11(21):2910-24.
1997: Chen B; Lambowitz A M
De novo and DNA primer-mediated initiation of cDNA synthesis by the mauriceville retroplasmid reverse transcriptase involve recognition of a 3' CCA sequence.
Journal of molecular biology 1997;271(3):311-32.
1997: Chiang C C; Lambowitz A M
The Mauriceville retroplasmid reverse transcriptase initiates cDNA synthesis de novo at the 3' end of tRNAs.
Molecular and cellular biology 1997;17(8):4526-35.
1997: Eskes R; Yang J; Lambowitz A M; Perlman P S
Mobility of yeast mitochondrial group II introns: engineering a new site specificity and retrohoming via full reverse splicing.
Cell 1997;88(6):865-74.
1997: Wallweber G J; Mohr S; Rennard R; Caprara M G; Lambowitz A M
Characterization of Neurospora mitochondrial group I introns reveals different CYT-18 dependent and independent splicing strategies and an alternative 3' splice site for an intron ORF.
RNA (New York, N.Y.) 1997;3(2):114-31.
1996: Caprara M G; Lehnert V; Lambowitz A M; Westhof E
A tyrosyl-tRNA synthetase recognizes a conserved tRNA-like structural motif in the group I intron catalytic core.
Cell 1996;87(6):1135-45.
1996: Myers C A; Wallweber G J; Rennard R; Kemel Y; Caprara M G; Mohr G; Lambowitz A M
A tyrosyl-tRNA synthetase suppresses structural defects in the two major helical domains of the group I intron catalytic core.
Journal of molecular biology 1996;262(2):87-104.
1996: Saldanha R; Ellington A; Lambowitz A M
Analysis of the CYT-18 protein binding site at the junction of stacked helices in a group I intron RNA by quantitative binding assays and in vitro selection.
Journal of molecular biology 1996;261(1):23-42.
1996: Yang J; Zimmerly S; Perlman P S; Lambowitz A M
Efficient integration of an intron RNA into double-stranded DNA by reverse splicing.
Nature 1996;381(6580):332-5.
1996: Caprara M G; Mohr G; Lambowitz A M
A tyrosyl-tRNA synthetase protein induces tertiary folding of the group I intron catalytic core.
Journal of molecular biology 1996;257(3):512-31.
1995: Zimmerly S; Guo H; Eskes R; Yang J; Perlman P S; Lambowitz A M
A group II intron RNA is a catalytic component of a DNA endonuclease involved in intron mobility.
Cell 1995;83(4):529-38.
1995: Zimmerly S; Guo H; Perlman P S; Lambowitz A M
Group II intron mobility occurs by target DNA-primed reverse transcription.
Cell 1995;82(4):545-54.
1995: Moran J V; Zimmerly S; Eskes R; Kennell J C; Lambowitz A M; Butow R A; Perlman P S
Mobile group II introns of yeast mitochondrial DNA are novel site-specific retroelements.
Molecular and cellular biology 1995;15(5):2828-38.
1995: Kennell J C; Saville B J; Mohr S; Kuiper M T; Sabourin J R; Collins R A; Lambowitz A M
The VS catalytic RNA replicates by reverse transcription as a satellite of a retroplasmid.
Genes & development 1995;9(3):294-303.
1995: Saldanha R J; Patel S S; Surendran R; Lee J C; Lambowitz A M
Involvement of Neurospora mitochondrial tyrosyl-tRNA synthetase in RNA splicing. A new method for purifying the protein and characterization of physical and enzymatic properties pertinent to splicing.
Biochemistry 1995;34(4):1275-87.
1994: Chiang C C; Kennell J C; Wanner L A; Lambowitz A M
A mitochondrial retroplasmid integrates into mitochondrial DNA by a novel mechanism involving the synthesis of a hybrid cDNA and homologous recombination.
Molecular and cellular biology 1994;14(10):6419-32.
1994: Mohr G; Caprara M G; Guo Q; Lambowitz A M
A tyrosyl-tRNA synthetase can function similarly to an RNA structure in the Tetrahymena ribozyme.
Nature 1994;370(6485):147-50.
1994: Kennell J C; Wang H; Lambowitz A M
The Mauriceville plasmid of Neurospora spp. uses novel mechanisms for initiating reverse transcription in vivo.
Molecular and cellular biology 1994;14(5):3094-107.
1993: Wang H; Lambowitz A M
The Mauriceville plasmid reverse transcriptase can initiate cDNA synthesis de novo and may be related to reverse transcriptase and DNA polymerase progenitor.
Cell 1993;75(6):1071-81.
1993: Mohr G; Perlman P S; Lambowitz A M
Evolutionary relationships among group II intron-encoded proteins and identification of a conserved domain that may be related to maturase function.
Nucleic acids research 1993;21(22):4991-7.
1993: Wang H; Lambowitz A M
Reverse transcription of the Mauriceville plasmid of Neurospora. Lack of ribonuclease H activity associated with the reverse transcriptase and possible use of mitochondrial ribonuclease H.
The Journal of biological chemistry 1993;268(25):18951-9.
1993: Kennell J C; Moran J V; Perlman P S; Butow R A; Lambowitz A M
Reverse transcriptase activity associated with maturase-encoding group II introns in yeast mitochondria.
Cell 1993;73(1):133-46.
1993: Saldanha R; Mohr G; Belfort M; Lambowitz A M
Group I and group II introns.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1993;7(1):15-24.
1992: Wang H; Kennell J C; Kuiper M T; Sabourin J R; Saldanha R; Lambowitz A M
The Mauriceville plasmid of Neurospora crassa: characterization of a novel reverse transcriptase that begins cDNA synthesis at the 3' end of template RNA.
Molecular and cellular biology 1992;12(11):5131-44.
1992: Guo Q; Lambowitz A M
A tyrosyl-tRNA synthetase binds specifically to the group I intron catalytic core.
Genes & development 1992;6(8):1357-72.
1992: Mohr G; Zhang A; Gianelos J A; Belfort M; Lambowitz A M
The neurospora CYT-18 protein suppresses defects in the phage T4 td intron by stabilizing the catalytically active structure of the intron core.
Cell 1992;69(3):483-94.
1992: Nargang F E; Pande S; Kennell J C; Akins R A; Lambowitz A M
Evidence that a 1.6 kilobase region of Neurospora mtDNA was derived by insertion of part of the LaBelle mitochondrial plasmid.
Nucleic acids research 1992;20(5):1101-8.
1992: Turcq B; Dobinson K F; Serizawa N; Lambowitz A M
A protein required for RNA processing and splicing in Neurospora mitochondria is related to gene products involved in cell cycle protein phosphatase functions.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(5):1676-80.
1991: Mohr G; Lambowitz A M
Integration of a group I intron into a ribosomal RNA sequence promoted by a tyrosyl-tRNA synthetase.
Nature 1991;354(6349):164-7.
1991: Kubelik A R; Turcq B; Lambowitz A M
The Neurospora crassa cyt-20 gene encodes cytosolic and mitochondrial valyl-tRNA synthetases and may have a second function in addition to protein synthesis.
Molecular and cellular biology 1991;11(8):4022-35.
1991: Kittle J D; Mohr G; Gianelos J A; Wang H; Lambowitz A M
The Neurospora mitochondrial tyrosyl-tRNA synthetase is sufficient for group I intron splicing in vitro and uses the carboxy-terminal tRNA-binding domain along with other regions.
Genes & development 1991;5(6):1009-21.
1991: Schulte U; Lambowitz A M
The LaBelle mitochondrial plasmid of Neurospora intermedia encodes a novel DNA polymerase that may be derived from a reverse transcriptase.
Molecular and cellular biology 1991;11(3):1696-706.
1991: Guo Q B; Akins R A; Garriga G; Lambowitz A M
Structural analysis of the Neurospora mitochondrial large rRNA intron and construction of a mini-intron that shows protein-dependent splicing.
The Journal of biological chemistry 1991;266(3):1809-19.
1990: Lambowitz A M; Perlman P S
Involvement of aminoacyl-tRNA synthetases and other proteins in group I and group II intron splicing.
Trends in biochemical sciences 1990;15(11):440-4.
1990: Akins R A; Lambowitz A M
Analysis of large deletions in the Mauriceville and Varkud mitochondrial plasmids of Neurospora.
Current genetics 1990;18(4):365-9.
1990: Cherniack A D; Garriga G; Kittle J D; Akins R A; Lambowitz A M
Function of Neurospora mitochondrial tyrosyl-tRNA synthetase in RNA splicing requires an idiosyncratic domain not found in other synthetases.
Cell 1990;62(4):745-55.
1990: Kuiper M T; Sabourin J R; Lambowitz A M
Identification of the reverse transcriptase encoded by the Mauriceville and Varkud mitochondrial plasmids of Neurospora.
The Journal of biological chemistry 1990;265(12):6936-43.
1990: Kubelik A R; Kennell J C; Akins R A; Lambowitz A M
Identification of Neurospora mitochondrial promoters and analysis of synthesis of the mitochondrial small rRNA in wild-type and the promoter mutant [poky].
The Journal of biological chemistry 1990;265(8):4515-26.
1989: Drygas M E; Lambowitz A M; Nargang F E
Cloning and analysis of the Neurospora crassa gene for cytochrome c heme lyase.
The Journal of biological chemistry 1989;264(30):17897-906.
1989: Kennell J C; Lambowitz A M
Development of an in vitro transcription system for Neurospora crassa mitochondrial DNA and identification of transcription initiation sites.
Molecular and cellular biology 1989;9(9):3603-13.
1989: Dobinson K F; Henderson M; Kelley R L; Collins R A; Lambowitz A M
Mutations in nuclear gene cyt-4 of Neurospora crassa result in pleiotropic defects in processing and splicing of mitochondrial RNAs.
Genetics 1989;123(1):97-108.
1989: Majumder A L; Akins R A; Wilkinson J G; Kelley R L; Snook A J; Lambowitz A M
Involvement of tyrosyl-tRNA synthetase in splicing of group I introns in Neurospora crassa mitochondria: biochemical and immunochemical analyses of splicing activity.
Molecular and cellular biology 1989;9(5):2089-104.
1989: Lambowitz A M; Sabourin J R; Bertrand H; Nickels R; McIntosh L
Immunological identification of the alternative oxidase of Neurospora crassa mitochondria.
Molecular and cellular biology 1989;9(3):1362-4.
1989: Lambowitz A M
Infectious introns.
Cell 1989;56(3):323-6.
1989: Akins R A; Kelley R L; Lambowitz A M
Characterization of mutant mitochondrial plasmids of Neurospora spp. that have incorporated tRNAs by reverse transcription.
Molecular and cellular biology 1989;9(2):678-91.
1988: Akins R A; Grant D M; Stohl L L; Bottorff D A; Nargang F E; Lambowitz A M
Nucleotide sequence of the Varkud mitochondrial plasmid of Neurospora and synthesis of a hybrid transcript with a 5' leader derived from mitochondrial RNA.
Journal of molecular biology 1988;204(1):1-25.
1988: Kuiper M T; Lambowitz A M
A novel reverse transcriptase activity associated with mitochondrial plasmids of Neurospora.
Cell 1988;55(4):693-704.
1986: Akins R A; Kelley R L; Lambowitz A M
Mitochondrial plasmids of Neurospora: integration into mitochondrial DNA and evidence for reverse transcription in mitochondria.
Cell 1986;47(4):505-16.
1986: Garriga G; Lambowitz A M
Protein-dependent splicing of a group I intron in ribonucleoprotein particles and soluble fractions.
Cell 1986;46(5):669-80.
1986: Garriga G; Lambowitz A M; Inoue T; Cech T R
Mechanism of recognition of the 5' splice site in self-splicing group I introns.
Nature 1986;322(6074):86-9.
1986: Vincent R D; Goewert R; Goldman W E; Kobayashi G S; Lambowitz A M; Medoff G
Classification of Histoplasma capsulatum isolates by restriction fragment polymorphisms.
Journal of bacteriology 1986;165(3):813-8.
1986: Lambowitz A M; Akins R A; Kelley R L; Pande S; Nargang F E
Mitochondrial plasmids of Neurospora and other filamentous fungi.
Basic life sciences 1986;40():83-92.
1984: Garriga G; Lambowitz A M
RNA splicing in neurospora mitochondria: self-splicing of a mitochondrial intron in vitro.
Cell 1984;39(3 Pt 2):631-41.
1984: Nargang F E; Bell J B; Stohl L L; Lambowitz A M
The DNA sequence and genetic organization of a Neurospora mitochondrial plasmid suggest a relationship to introns and mobile elements.
Cell 1984;38(2):441-53.
1984: Stohl L L; Akins R A; Lambowitz A M
Characterization of deletion derivatives of an autonomously replicating Neurospora plasmid.
Nucleic acids research 1984;12(15):6169-78.
1984: Garriga G; Bertrand H; Lambowitz A M
RNA splicing in Neurospora mitochondria: nuclear mutants defective in both splicing and 3' end synthesis of the large rRNA.
Cell 1984;36(3):623-34.
1983: Garriga G; Lambowitz A M
RNA splicing in Neurospora mitochondria. The large rRNA intron contains a noncoded, 5'-terminal guanosine residue.
The Journal of biological chemistry 1983;258(24):14745-8.
1983: Stohl L L; Lambowitz A M
A colony filter-hybridization procedure for the filamentous fungus Neurospora crassa.
Analytical biochemistry 1983;134(1):82-5.
1983: Nargang F E; Bell J B; Stohl L L; Lambowitz A M
A family of repetitive palindromic sequences found in Neurospora mitochondrial DNA is also found in a mitochondrial plasmid DNA.
The Journal of biological chemistry 1983;258(7):4257-60.
1983: Stohl L L; Lambowitz A M
Construction of a shuttle vector for the filamentous fungus Neurospora crassa.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(4):1058-62.
1982: Bertrand H; Bridge P; Collins R A; Garriga G; Lambowitz A M
RNA splicing in Neurospora mitochondria. Characterization of new nuclear mutants with defects in splicing the mitochondrial large rRNA.
Cell 1982;29(2):517-26.
1982: Stohl L L; Collins R A; Cole M D; Lambowitz A M
Characterization of two new plasmid DNAs found in mitochondria of wild-type Neurospora intermedia strains.
Nucleic acids research 1982;10(5):1439-58.
1981: Grimm M F; Cole M D; Lambowitz A M
Ribonucleic acid splicing in Neurospora Mitochondria: secondary structure of the 35S ribosomal precursor ribonucleic acid investigated by digestion with ribonuclease III and by electron microscopy.
Biochemistry 1981;20(10):2836-42.
1981: Collins R A; Stohl L L; Cole M D; Lambowitz A M
Characterization of a novel plasmid DNA found in mitochondria of N. crassa.
Cell 1981;24(2):443-52.
1981: Green M R; Grimm M F; Goewert R R; Collins R A; Cole M D; Lambowitz A M; Heckman J E; Yin S; RajBhandary U L
Transcripts and processing patterns for the ribosomal RNA and transfer RNA region of Neurospora crassa mitochondrial DNA.
The Journal of biological chemistry 1981;256(4):2027-34.
1980: Bertrand H; Collins R A; Stohl L L; Goewert R R; Lambowitz A M
Deletion mutants of Neurospora crassa mitochondrial DNA and their relationship to the "stop-start" growth phenotype.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(10):6032-6.

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