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Bernhard Lämmle

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Sumit Som; Deirdra R Terrell; Cassandra C Deford; James N George; Mandi L Kaiser; Johanna A Kremer-Hovinga; Bernhard Lämmle; Sara K Vesely
Decreasing frequency of plasma exchange complications in patients treated for thrombotic thrombocytopenic purpura-hemolytic uremic syndrome, 1996 to 2011.
Tobias A. Fuchs; Johanna A Kremer-Hovinga; Daphne Schatzberg; Denisa D Wagner; Bernhard Lämmle
Circulating DNA and myeloperoxidase indicate disease activity in patients with thrombotic microangiopathies.
Spero R Cataland; James C Gilbert; Bernd Jilma; Johanna A Kremer-Hovinga; Bernhard Lämmle; Samuel J Machin; Pier M Mannucci; Flora Peyvandi; Gail Rock; Marie Scully; Haifeng Wu; Shangbin Yang; Paul Knoebl
Initial experience from a double-blind, placebo-controlled, clinical outcome study of ARC1779 in patients with thrombotic thrombocytopenic purpura.

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2012: Sumit Som; Deirdra R Terrell; Cassandra C Deford; James N George; Mandi L Kaiser; Johanna A Kremer-Hovinga; Bernhard Lämmle; Sara K Vesely
Decreasing frequency of plasma exchange complications in patients treated for thrombotic thrombocytopenic purpura-hemolytic uremic syndrome, 1996 to 2011.
Transfusion 2012;52(12):2525-32; quiz 2524.
2012: Tobias A. Fuchs; Johanna A Kremer-Hovinga; Daphne Schatzberg; Denisa D Wagner; Bernhard Lämmle
Circulating DNA and myeloperoxidase indicate disease activity in patients with thrombotic microangiopathies.
Blood 2012;120(6):1157-64.
2012: Spero R Cataland; James C Gilbert; Bernd Jilma; Johanna A Kremer-Hovinga; Bernhard Lämmle; Samuel J Machin; Pier M Mannucci; Flora Peyvandi; Gail Rock; Marie Scully; Haifeng Wu; Shangbin Yang; Paul Knoebl
Initial experience from a double-blind, placebo-controlled, clinical outcome study of ARC1779 in patients with thrombotic thrombocytopenic purpura.
American journal of hematology 2012;87(4):430-2.
2012: James N George; Johanna A Kremer-Hovinga; Deirdra R Terrell; Sara K Vesely; Bernhard Lämmle
Thrombotic microangiopathic syndromes associated with drugs, HIV infection, hematopoietic stem cell transplantation and cancer.
Presse médicale (Paris, France : 1983) 2012;41(3 Pt 2):e177-88.
2012: Rahel Froehlich-Zahnd; James N George; Khatira Aboulfatova; Ulrich Budde; Jing-Fei Dong; Bernhard Lämmle; Brenda M Luken; Irmela Sulzer; Deirdra R Terrell; Sara K Vesely; Jan Voorberg; Johanna A Kremer-Hovinga
Evidence for a role of anti-ADAMTS13 autoantibodies despite normal ADAMTS13 activity in recurrent thrombotic thrombocytopenic purpura.
Haematologica 2012;97(2):297-303.
2012: Johanna A Kremer-Hovinga; Bernhard Lämmle
Role of ADAMTS13 in the pathogenesis, diagnosis, and treatment of thrombotic thrombocytopenic purpura.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2012;2012():610-6.
2011: Lorenzo Alberio; Bernhard Lämmle
On the dosing of lepirudin.
British journal of clinical pharmacology 2011;72(4):717.
2011: Deirdra R Terrell; James N George; Johanna A Kremer-Hovinga; Bernhard Lämmle; David G Motto; Sara K Vesely
Blood group O and black race are independent risk factors for thrombotic thrombocytopenic purpura associated with severe ADAMTS13 deficiency.
Transfusion 2011;51(10):2237-43.
2011: R Luginbühl; G Barizzi; Irmela Sulzer; Bernhard Lämmle; Lorenzo Alberio
Screening for lupus anticoagulant: improving the performance of the lupus-sensitive PTT-LA.
International journal of laboratory hematology 2011;33(2):168-75.
2011: Alexander Brill; Tobias A. Fuchs; Anil K Chauhan; Janie J Yang; Simon F De Meyer; Maria Köllnberger; Thomas W Wakefield; Bernhard Lämmle; Steffen Massberg; Denisa D Wagner
von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models.
Blood 2011;117(4):1400-7.
2011: Pirmin Schmid; Heinz Zimmermann; Andreas Hirt; Daniel Inderbitzin; Hans-Peter Kohler; Bernhard Lämmle; Martin Luginbühl; Andrea Mordasini; Bruno Regli; Lorenzo Alberio
Low-dose recombinant factor VIIa for massive bleeding: a single centre observational cohort study with 73 patients.
Swiss medical weekly 2011;141():w13213.
2010: Deirdra R Terrell; Sara Vesely; Bernhard Lämmle; Johanna A Kremer Hovinga; James N George
Different disparities of gender and race among the thrombotic thrombocytopenic purpura and hemolytic-uremic syndromes.
American journal of hematology 2010;85(11):844-7.
2010: Johanna A Kremer Hovinga; Sara K Vesely; Deirdra R Terrell; Bernhard Lämmle; James N George
Survival and relapse in patients with thrombotic thrombocytopenic purpura.
Blood 2010;115(8):1500-11; quiz 1662.
2010: Jörg Isenegger; Niklaus Meier; Bernhard Lämmle; Lorenzo Alberio; Urs Fischer; Krassen Nedeltchev; Jan Gralla; Hans-Peter Kohler; Heinrich P Mattle; Marcel Arnold
D-dimers predict stroke subtype when assessed early.
Cerebrovascular diseases (Basel, Switzerland) 2010;29(1):82-6.
2010: Patrick Dubach; Georgios Mantokoudis; Bernhard Lämmle
Rumpel-Leede sign in thrombocytopenia due to Epstein-Barr virus-induced mononucleosis.
British journal of haematology 2010;148(1):2.
2009: Giuseppe Colucci; Lorenzo Alberio; Maximilian Jahns; Peter Keller; Simon Steiner; Ilka Rüsges-Wolter; Bernhard Lämmle
Effective therapy with tranexamic acid in a case of chronic disseminated intravascular coagulation with acquired alpha2-antiplasmin deficiency associated with AL amyloidosis.
Thrombosis and haemostasis 2009;102(6):1285-7.
2009: S Schneiter; G Colucci; Irmela Sulzer; G Barizzi; Bernhard Lämmle; Lorenzo Alberio
Variability of anti-PF4/heparin antibody results obtained by the rapid testing system ID-H/PF4-PaGIA.
Journal of thrombosis and haemostasis : JTH 2009;7(10):1649-55.
2009: April S Kennedy; Qurana F Lewis; James G Scott; Johanna A Kremer-Hovinga; Bernhard Lämmle; Deirdra R Terrell; Sara Vesely; James N George
Cognitive deficits after recovery from thrombotic thrombocytopenic purpura.
Transfusion 2009;49(6):1092-101.
2009: Karen K Swisher; Deirdra R Terrell; Sara Vesely; Johanna A Kremer-Hovinga; Bernhard Lämmle; James N George
Clinical outcomes after platelet transfusions in patients with thrombotic thrombocytopenic purpura.
Transfusion 2009;49(5):873-87.
2009: Melody Benjamin; Deirdra R Terrell; Sara Vesely; Gene W Voskuhl; Bruce J Dezube; Johanna A Kremer-Hovinga; Bernhard Lämmle; James N George
Frequency and significance of HIV infection among patients diagnosed with thrombotic thrombocytopenic purpura.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2009;48(8):1129-37.
2009: Martina Tschudi; Bernhard Lämmle; Lorenzo Alberio
Dosing lepirudin in patients with heparin-induced thrombocytopenia and normal or impaired renal function: a single-center experience with 68 patients.
Blood 2009;113(11):2402-9.
2008: Sara C Meyer; Ramzi Jeddi; Balkis Meddeb; Emna Gouider; Bernhard Lämmle; Johanna A Kremer-Hovinga
A first case of congenital TTP on the African continent due to a new homozygous mutation in the catalytic domain of ADAMTS13.
Annals of hematology 2008;87(8):663-6.
2008: Charity A Karpac; Xiaoning Li; Deirdra R Terrell; Johanna A Kremer-Hovinga; Bernhard Lämmle; Sara Vesely; James N George
Sporadic bloody diarrhoea-associated thrombotic thrombocytopenic purpura-haemolytic uraemic syndrome: an adult and paediatric comparison.
British journal of haematology 2008;141(5):696-707.
2008: James N George; Johanna A Kremer-Hovinga; Deirdra R Terrell; Sara Vesely; Bernhard Lämmle
The Oklahoma Thrombotic Thrombocytopenic Purpura-Hemolytic Uremic Syndrome Registry: the Swiss connection.
European journal of haematology 2008;80(4):277-86.
2008: Lars M Asmis; Reto Asmis; Irmela Sulzer; Miha Furlan; Bernhard Lämmle
Contact system activation in human sepsis - 47kD HK, a marker of sepsis severity?
Swiss medical weekly 2008;138(9-10):142-9.
2008: Manuel Zürcher; Irmela Sulzer; Gabriela Barizzi; Bernhard Lämmle; Lorenzo Alberio
Stability of coagulation assays performed in plasma from citrated whole blood transported at ambient temperature.
Thrombosis and haemostasis 2008;99(2):416-26.
2008: Bernhard Lämmle; Johanna A Kremer-Hovinga; James N George
Acquired thrombotic thrombocytopenic purpura: ADAMTS13 activity, anti-ADAMTS13 autoantibodies and risk of recurrent disease.
Haematologica 2008;93(2):172-7.
2007: Robert M Kalicki; Fabienne Aregger; Lorenzo Alberio; Bernhard Lämmle; Felix J Frey; Dominik Uehlinger
Use of the pentasaccharide fondaparinux as an anticoagulant during haemodialysis.
Thrombosis and haemostasis 2007;98(6):1200-7.
2007: Johanna A Kremer-Hovinga; Sacha Zeerleder; P Kessler; Thalia Romani de Wit; Jan A van Mourik; C Erik Hack; Hugo ten Cate; Pieter H Reitsma; Walter A Wuillemin; Bernhard Lämmle
ADAMTS-13, von Willebrand factor and related parameters in severe sepsis and septic shock.
Journal of thrombosis and haemostasis : JTH 2007;5(11):2284-90.
2007: Axel Rüfer; Doreen Brodmann; Michael Gregor; Johanna A Kremer-Hovinga; Bernhard Lämmle; Walter A Wuillemin
Rituximab for acute plasma-refractory thrombotic thrombocytopenic purpura. A case report and concise review of the literature.
Swiss medical weekly 2007;137(37-38):518-24.
2007: S C Meyer; Irmela Sulzer; Bernhard Lämmle; Johanna A Kremer-Hovinga
Hyperbilirubinemia interferes with ADAMTS-13 activity measurement by FRETS-VWF73 assay: diagnostic relevance in patients suffering from acute thrombotic microangiopathies.
Journal of thrombosis and haemostasis : JTH 2007;5(4):866-7.
2007: Tapani Ruutu; Giovanni Barosi; Richard J Benjamin; Richard E Clark; James N George; Alois Gratwohl; Ernst Holler; Massimo Iacobelli; Karim Kentouche; Bernhard Lämmle; Joel L Moake; Paul Richardson; Gérard Socié; Zella R Zeigler; Dietger Niederwieser; Tiziano Barbui
Diagnostic criteria for hematopoietic stem cell transplant-associated microangiopathy: results of a consensus process by an International Working Group.
Haematologica 2007;92(1):95-100.
2007: Sacha Zeerleder; Verena Schroeder; Bernhard Lämmle; Walter A Wuillemin; C Erik Hack; Hans P Kohler
Factor XIII in severe sepsis and septic shock.
Thrombosis research 2007;119(3):311-8.
2006: Ralph Kickuth; Suzanne Anderson; Kristiina Peter-Salonen; Bernhard Lämmle; Stefan Eggli; Jürgen Triller
Hemophilia A pseudoaneurysm in a patient with high responding inhibitors complicating total knee arthroplasty: embolization: a cost-reducing alternative to medical therapy.
Cardiovascular and interventional radiology 2006;29(6):1132-5.
2006: Reinhard Schneppenheim; Johanna A Kremer-Hovinga; Tim Becker; Ulrich Budde; Diana Karpman; Wolfgang Brockhaus; Ingrid Hrachovinová; Bartosz Korczowski; Florian Oyen; Simon Rittich; Johannes von Rosen; Geir Tjønnfjord; John E Pimanda; Thomas F Wienker; Bernhard Lämmle
A common origin of the 4143insA ADAMTS13 mutation.
Thrombosis and haemostasis 2006;96(1):3-6.
2006: John-John B Schnog; Soraya Krieg; Sakir Akin; Bernhard Lämmle; D P M Brandjes; Melvin R Mac Gillavry; Fred D Muskiet; Ashley J Duits; Johanna A Kremer Hovinga
ADAMTS13 activity in sickle cell disease.
American journal of hematology 2006;81(7):492-8.
2006: Bernhard Lämmle; Johanna A Kremer-Hovinga
A new tool to further explore the role of ADAMTS-13 in health and disease.
Journal of thrombosis and haemostasis : JTH 2006;4(5):952-4.
2006: Stefano Fontana; Johanna A Kremer-Hovinga; Bernhard Lämmle; Behrouz Mansouri Taleghani
Treatment of thrombotic thrombocytopenic purpura.
Vox sanguinis 2006;90(4):245-54.
2005: Soraya Krieg; Jan-Dirk Studt; Irmela Sulzer; Bernhard Lämmle; Johanna A Kremer Hovinga
Is factor V Leiden a risk factor for thrombotic microangiopathies without severe ADAMTS 13 deficiency?
Thrombosis and haemostasis 2005;94(6):1186-9.
2005: Manfred Rieger; Pier Mannuccio Mannucci; Johanna A Kremer-Hovinga; Andrea Herzog; Gabi Gerstenbauer; Christian Konetschny; Klaus Zimmermann; Inge Scharrer; Flora Peyvandi; Miriam Galbusera; Giuseppe Remuzzi; Martina Böhm; Barbara Plaimauer; Bernhard Lämmle; Friedrich Scheiflinger
ADAMTS13 autoantibodies in patients with thrombotic microangiopathies and other immunomediated diseases.
Blood 2005;106(4):1262-7.
2005: Bernhard Lämmle; Johanna A Kremer-Hovinga; Lorenzo Alberio
Thrombotic thrombocytopenic purpura.
Journal of thrombosis and haemostasis : JTH 2005;3(8):1663-75.
2005: Deirdra R Terrell; L A Williams; Sara Vesely; Bernhard Lämmle; J A K Hovinga; James N George
The incidence of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: all patients, idiopathic patients, and patients with severe ADAMTS-13 deficiency.
Journal of thrombosis and haemostasis : JTH 2005;3(7):1432-6.
2005: Jan-Dirk Studt; Gerhard Antoine; Martin Hermann; Manfred Rieger; Friedrich Scheiflinger; Johanna A Kremer Hovinga; Bernhard Lämmle
Fatal congenital thrombotic thrombocytopenic purpura with apparent ADAMTS13 inhibitor: in vitro inhibition of ADAMTS13 activity by hemoglobin.
Blood 2005;105(2):542-4.
2004: Christoph Klaus; Barbara Plaimauer; Jan-Dirk Studt; Friedrich Dorner; Bernhard Lämmle; Pier Mannuccio Mannucci; Friedrich Scheiflinger
Epitope mapping of ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura.
Blood 2004;103(12):4514-9.
2004: Jan-Dirk Studt; Radovan Radonic; Vladimir Gasparovic; Dragutin Ivanovic; Marijan Merkler; Urs Wirthmueller; Clemens Dahinden; Miha Furlan; Johanna A Kremer Hovinga; Bernhard Lämmle
Familial acquired thrombotic thrombocytopenic purpura: ADAMTS13 inhibitory autoantibodies in identical twins.
Blood 2004;103(11):4195-7.
2004: Lara Chilver-Stainer; Bernhard Lämmle; Lorenzo Alberio
Titre of anti-heparin/PF4-antibodies and extent of in vivo activation of the coagulation and fibrinolytic systems.
Thrombosis and haemostasis 2004;91(2):276-82.
2004: Bernhard Lämmle; Johanna A Kremer-Hovinga; Jan-Dirk Studt; Behrouz Mansouri Taleghani; Lorenzo Alberio
Thrombotic thrombocytopenic purpura.
The hematology journal : the official journal of the European Haematology Association / EHA 2004;5 Suppl 3():S6-11.
2004: Johanna A Kremer Hovinga; Jan-Dirk Studt; Lorenzo Alberio; Bernhard Lämmle
von Willebrand factor-cleaving protease (ADAMTS-13) activity determination in the diagnosis of thrombotic microangiopathies: the Swiss experience.
Seminars in hematology 2004;41(1):75-82.
2004: Stefano Fontana; Jan-Dirk Studt; Lorenzo Alberio; Bernhard Lämmle; Johanna A Kremer Hovinga; Behrouz Mansouri Taleghani
Plasma therapy in thrombotic thrombocytopenic purpura: review of the literature and the Bern experience in a subgroup of patients with severe acquired ADAMTS-13 deficiency.
Seminars in hematology 2004;41(1):48-59.
2004: Bernhard Lämmle; James N George
Thrombotic thrombocytopenic purpura: advances in pathophysiology, diagnosis, and treatment--introduction.
Seminars in hematology 2004;41(1):1-3.
2003: Franziska Demarmels Biasiutti; Daniela Berger; Heinrich P Mattle; Bernhard Lämmle; Walter A Wuillemin
Hemostatic risk factors in ischemic stroke.
Thrombosis and haemostasis 2003;90(6):1094-9.
2003: Johanna A Kremer-Hovinga; Jan-Dirk Studt; Bernhard Lämmle
The von Willebrand factor-cleaving protease (ADAMTS-13) and the diagnosis of thrombotic thrombocytopenic purpura (TTP).
Pathophysiology of haemostasis and thrombosis 2003;33(5-6):417-21.
2003: Jan-Dirk Studt; M Böhm; U Budde; J-P Girma; K Varadi; Bernhard Lämmle
Measurement of von Willebrand factor-cleaving protease (ADAMTS-13) activity in plasma: a multicenter comparison of different assay methods.
Journal of thrombosis and haemostasis : JTH 2003;1(9):1882-7.
2003: D Friess; Bernhard Lämmle; Lorenzo Alberio
Qualitative platelet defect and thrombohaemorrhagic complications in a patient with polycythaemia vera. Case 10.
Hämostaseologie 2003;23(3):138-43.
2003: P Baud; Andreas Tobler; Bernhard Lämmle; Lorenzo Alberio
Acquired von Willebrand syndrome in a myeloproliferative disorder. Case 6.
Hämostaseologie 2003;23(3):121-4.
2003: A Winkler; Johanna A Kremer-Hovinga; Valentina Bianchi; Jan-Dirk Studt; Bernhard Lämmle
Schistocytic anaemia, severe thrombocytopenia, and renal dysfunction: thrombotic microangiopathy due to severe acquired ADAMTS-13 deficiency. Case 2.
Hämostaseologie 2003;23(3):103-8.
2003: Sacha Zeerleder; Bas Zwart; Walter A Wuillemin; Lucien A Aarden; A B Johan Groeneveld; Christoph Caliezi; Annemarie E M van Nieuwenhuijze; Gerard van Mierlo; Anke J M Eerenberg; Bernhard Lämmle; C Erik Hack
Elevated nucleosome levels in systemic inflammation and sepsis.
Critical care medicine 2003;31(7):1947-51.
2003: Sara Vesely; James N George; Bernhard Lämmle; Jan-Dirk Studt; Lorenzo Alberio; Mayez A El-Harake; Gary E Raskob
ADAMTS13 activity in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: relation to presenting features and clinical outcomes in a prospective cohort of 142 patients.
Blood 2003;102(1):60-8.
2003: Jan-Dirk Studt; Johanna A Kremer-Hovinga; Lorenzo Alberio; Valentina Bianchi; Bernhard Lämmle
Von Willebrand factor-cleaving protease (ADAMTS-13) activity in thrombotic microangiopathies: diagnostic experience 2001/2002 of a single research laboratory.
Swiss medical weekly 2003;133(23-24):325-32.
2003: Lorenzo Alberio; Sabine Kimmerle; Annalies Baumann; Behrouz Mansouri Taleghani; Franziska Demarmels Biasiutti; Bernhard Lämmle
Rapid determination of anti-heparin/platelet factor 4 antibody titers in the diagnosis of heparin-induced thrombocytopenia.
The American journal of medicine 2003;114(7):528-36.
2003: Nils Kucher; Hans P Kohler; T Dornhöfer; Dieter Wallmann; Bernhard Lämmle
Accuracy of D-dimer/fibrinogen ratio to predict pulmonary embolism: a prospective diagnostic study.
Journal of thrombosis and haemostasis : JTH 2003;1(4):708-13.
2003: Bernhard Lämmle; Franziska Demarmels Biasiutti; Maurice Redondo; Walter A Wuillemin
Prospective cross-sectional study of haemostatic factors in patients with and without coronary artery disease.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2003;14(3):313.
2003: Gerhard Antoine; Klaus Zimmermann; Barbara Plaimauer; Monika Grillowitzer; Jan-Dirk Studt; Bernhard Lämmle; Friedrich Scheiflinger
ADAMTS13 gene defects in two brothers with constitutional thrombotic thrombocytopenic purpura and normalization of von Willebrand factor-cleaving protease activity by recombinant human ADAMTS13.
British journal of haematology 2003;120(5):821-4.
2003: Bernhard Lämmle
[Clinical problems with oral anticoagulation -- 3 case reports].
Therapeutische Umschau. Revue thérapeutique 2003;60(1):63-6.
2002: Barbara Plaimauer; Klaus Zimmermann; Dirk Völkel; Gerhard Antoine; Randolf J Kerschbaumer; Pegah Jenab; Miha Furlan; Helen Gerritsen; Bernhard Lämmle; Hans Peter Schwarz; Friedrich Scheiflinger
Cloning, expression, and functional characterization of the von Willebrand factor-cleaving protease (ADAMTS13).
Blood 2002;100(10):3626-32.
2002: Walter A Wuillemin; K atherina M Gasser; Sacha Zeerleder; Bernhard Lämmle
Evaluation of a Platelet Function Analyser (PFA-100) in patients with a bleeding tendency.
Swiss medical weekly 2002;132(31-32):443-8.
2002: Christoph Caliezi; Sacha Zeerleder; Maurice Redondo; Bruno Regli; Hans Rothen; Regula Zürcher-Zenklusen; Robert Rieben; Jan Devay; C Erik Hack; Bernhard Lämmle; Walter A Wuillemin
C1-inhibitor in patients with severe sepsis and septic shock: beneficial effect on renal dysfunction.
Critical care medicine 2002;30(8):1722-8.
2002: Valentina Bianchi; Rodolfo Robles; Lorenzo Alberio; Miha Furlan; Bernhard Lämmle
Von Willebrand factor-cleaving protease (ADAMTS13) in thrombocytopenic disorders: a severely deficient activity is specific for thrombotic thrombocytopenic purpura.
Blood 2002;100(2):710-3.
2002: Miha Furlan; Bernhard Lämmle
Assays of von Willebrand factor-cleaving protease: a test for diagnosis of familial and acquired thrombotic thrombocytopenic purpura.
Seminars in thrombosis and hemostasis 2002;28(2):167-72.
2002: Christoph Merlo; Walter A Wuillemin; Maurice Redondo; Miha Furlan; Irmela Sulzer; Johanna A Kremer-Hovinga; Bernd R Binder; Bernhard Lämmle
Elevated levels of plasma prekallikrein, high molecular weight kininogen and factor XI in coronary heart disease.
Atherosclerosis 2002;161(2):261-7.
2002: Lars M Asmis; Irmela Sulzer; Miha Furlan; Bernhard Lämmle
Prekallikrein deficiency: the characteristic normalization of the severely prolonged aPTT following increased preincubation time is due to autoactivation of factor XII.
Thrombosis research 2002;105(6):463-70.
2002: Sacha Zeerleder; Thomas Mauron; Bernhard Lämmle; Walter A Wuillemin
Effect of low-molecular weight dextran sulfate on coagulation and platelet function tests.
Thrombosis research 2002;105(5):441-6.
2002: James N George; J Evan Sadler; Bernhard Lämmle
Platelets: thrombotic thrombocytopenic purpura.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2002;():315-34.
2001: Helen Gerritsen; Rodolfo Robles; Bernhard Lämmle; Miha Furlan
Partial amino acid sequence of purified von Willebrand factor-cleaving protease.
Blood 2001;98(6):1654-61.
2001: Maurice Redondo; Christoph Caliezi; Franziska Demarmels Biasiutti; Bernhard Lämmle; Walter A Wuillemin
Increased fibrin monomer plasma concentration in stable coronary artery disease in patients without oral anticoagulation.
Atherosclerosis 2001;157(2):417-22.
2001: K Kobelt; Franziska Demarmels Biasiutti; H P Mattle; Bernhard Lämmle; Walter A Wuillemin
Protein Z in ischaemic stroke.
British journal of haematology 2001;114(1):169-73.
2001: Miha Furlan; Bernhard Lämmle
Aetiology and pathogenesis of thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome: the role of von Willebrand factor-cleaving protease.
Best practice & research. Clinical haematology 2001;14(2):437-54.
2001: José Barbot; Elísio Costa; M Guerra; M S Barreirinho; P Isvarlal; Rodolfo Robles; Helen Gerritsen; Bernhard Lämmle; Miha Furlan
Ten years of prophylactic treatment with fresh-frozen plasma in a child with chronic relapsing thrombotic thrombocytopenic purpura as a result of a congenital deficiency of von Willebrand factor-cleaving protease.
British journal of haematology 2001;113(3):649-51.
2001: Lorenzo Alberio; Bernhard Lämmle; Charles T Esmon
Protein C replacement in severe meningococcemia: rationale and clinical experience.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2001;32(9):1338-46.
2001: N Fünfsinn; Christoph Caliezi; Franziska Demarmels Biasiutti; Wolfgang C. Korte; A Z'Brun; Iris Baumgartner; M Ulrich; C Cottier; Bernhard Lämmle; Walter A Wuillemin
Rapid D-dimer testing and pre-test clinical probability in the exclusion of deep venous thrombosis in symptomatic outpatients.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2001;12(3):165-70.
2001: Stefano Fontana; Helen Gerritsen; Johanna A Kremer-Hovinga; Miha Furlan; Bernhard Lämmle
Microangiopathic haemolytic anaemia in metastasizing malignant tumours is not associated with a severe deficiency of the von Willebrand factor-cleaving protease.
British journal of haematology 2001;113(1):100-2.
2001: Maurice Redondo; V A Carroll; Thomas Mauron; Franziska Demarmels Biasiutti; Bernd R Binder; Bernhard Lämmle; Walter A Wuillemin
Hemostatic and fibrinolytic parameters in survivors of myocardial infarction: a low plasma level of plasmin-alpha2-antiplasmin complex is an independent predictor of coronary re-events.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2001;12(1):17-24.
2000: Christoph Caliezi; M Waber; D Pfiffner; H Saner; Bernhard Lämmle; Walter A Wuillemin
[Patient self-monitoring of oral anticoagulation with CoaguChek].
Schweizerische medizinische Wochenschrift 2000;130(24):916-23.
2000: Thomas Mauron; Bernhard Lämmle; Walter A Wuillemin
High molecular weight kininogen is cleaved by FXIa at three sites: Arg409-Arg410, Lys502-Thr503 and Lys325-Lys326.
Thrombosis and haemostasis 2000;83(5):709-14.
2000: Christoph Caliezi; G Reber; Bernhard Lämmle; P de Moerloose; Walter A Wuillemin
Agreement of D-dimer results measured by a rapid ELISA (VIDAS) before and after storage during 24h or transportation of the original whole blood samples.
Thrombosis and haemostasis 2000;83(1):177-8.
1999: Bettina Bolliger-Stucki; P Bucciarelli; Bernhard Lämmle; Miha Furlan
Fibrinogen Milano XIII (Aalpha 19 Arg-->Gly): a dysfunctional variant with an amino acid substitution in the N-terminal polymerization site.
Thrombosis research 1999;96(5):399-405.
1999: Helen Gerritsen; P L Turecek; Hans Peter Schwarz; Bernhard Lämmle; Miha Furlan
Assay of von Willebrand factor (vWF)-cleaving protease based on decreased collagen binding affinity of degraded vWF: a tool for the diagnosis of thrombotic thrombocytopenic purpura (TTP)
Thrombosis and haemostasis 1999;82(5):1386-9.
1999: Sacha Zeerleder; M Schloesser; Maurice Redondo; Walter A Wuillemin; Wolfgang Engel; Miha Furlan; Bernhard Lämmle
Reevaluation of the incidence of thromboembolic complications in congenital factor XII deficiency--a study on 73 subjects from 14 Swiss families.
Thrombosis and haemostasis 1999;82(4):1240-6.
1999: K Kriz-Kozak; Bernhard Lämmle
[46-year-old woman with multiple hematomas and bleeding of the base of the tongue: phenprocoumon poisoning].
Therapeutische Umschau. Revue thérapeutique 1999;56(9):541-3.
1999: Max Solenthaler; Bernhard Lämmle
[Severe hemorrhage, lymphocytosis and leukoerythroblastic blood picture--disseminated intravascular coagulation in metastatic prostate carcinoma and chronic lymphatic leukemia].
Therapeutische Umschau. Revue thérapeutique 1999;56(9):533-6.
1999: S Fontana; Bernhard Lämmle
[Chronic, hemorrhage-induced iron deficiency anemia in Osler disease].
Therapeutische Umschau. Revue thérapeutique 1999;56(9):526-8.
1999: A Bohler; Bernhard Lämmle
[Decreased Quick percentage, acquired factor X deficiency, hemarthrosis and ecchymosis: amyloidosis].
Therapeutische Umschau. Revue thérapeutique 1999;56(9):523-5.
1999: K Peter; M Furlan; Bernhard Lämmle
[Life-long hemorrhagic diathesis in a young man with unclottable global coagulation tests--congenital afibrinogenemia].
Therapeutische Umschau. Revue thérapeutique 1999;56(9):516-8.
1999: Sacha Zeerleder; L Asmis; Maurice Redondo; Irmela Sulzer; Bernhard Lämmle
[A patient with isolated prolongation of aPTT without hemorrhagic diathesis anamnesis: severe, hereditary factor XII deficiency].
Therapeutische Umschau. Revue thérapeutique 1999;56(9):509-12.
1999: A Bohler; Maurice Redondo; Bernhard Lämmle
[Increased thrombin time in a patient with multiple myeloma].
Therapeutische Umschau. Revue thérapeutique 1999;56(9):491-4.
1999: S Fontana; Sacha Zeerleder; Bernhard Lämmle
[Derailed oral anticoagulation with very high INR values and poor response to oral vitamin K--cholestasis as a possible cause].
Therapeutische Umschau. Revue thérapeutique 1999;56(9):477-80.
1999: Miha Furlan; Bernhard Lämmle
von Willebrand factor in thrombotic thrombocytopenic purpura.
Thrombosis and haemostasis 1999;82(2):592-600.
1999: Maurice Redondo; H H Watzke; B Stucki; Irmela Sulzer; Franziska Demarmels Biasiutti; Bernd R Binder; Miha Furlan; Bernhard Lämmle; Walter A Wuillemin
Coagulation factors II, V, VII, and X, prothrombin gene 20210G-->A transition, and factor V Leiden in coronary artery disease: high factor V clotting activity is an independent risk factor for myocardial infarction.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(4):1020-5.
1999: B Stucki; R Zenhäusern; B Biedermann; Francesco Baudo; Rosaria Redaelli; Bernhard Lämmle; Miha Furlan
Fibrinogens Bern IV, Bern V and Milano XI: three dysfunctional variants with amino acid substitutions in the thrombin cleavage site of the Aalpha-chain.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1999;10(2):93-9.
1999: B Stucki; P Schmutz; L Schmid; André Haeberli; Bernhard Lämmle; Miha Furlan
Fibrinogen St. Gallen I (gamma 292 Gly--> Val): evidence for structural alterations causing defective polymerization and fibrinogenolysis.
Thrombosis and haemostasis 1999;81(2):268-74.
1999: Miha Furlan; Rodolfo Robles; B Morselli; P Sandoz; Bernhard Lämmle
Recovery and half-life of von Willebrand factor-cleaving protease after plasma therapy in patients with thrombotic thrombocytopenic purpura.
Thrombosis and haemostasis 1999;81(1):8-13.
1999: Christoph Caliezi; N Fünfsinn; Thomas Mauron; Iris Baumgartner; Irmela Sulzer; M Ulrich; C Cottier; Franziska Demarmels Biasiutti; Bernhard Lämmle; Walter A Wuillemin
Performance of a new fibrin monomer assay to exclude deep vein thrombosis in symptomatic outpatients.
Thrombosis and haemostasis 1999;81(1):50-3.
1998: L Alberio; Bernhard Lämmle
Images in clinical medicine. Capnocytophaga canimorsus sepsis.
The New England journal of medicine 1998;339(25):1827.
1998: Miha Furlan; Rodolfo Robles; Miriam Galbusera; G Remuzzi; P A Kyrle; B Brenner; M Krause; I Scharrer; Volker Aumann; Uwe Mittler; Max Solenthaler; Bernhard Lämmle
von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome.
The New England journal of medicine 1998;339(22):1578-84.
1998: S Burri; Franziska Demarmels Biasiutti; Bernhard Lämmle; Walter A Wuillemin
[Comparison of Quick/INR values of whole capillary blood (CoaguChek Plus) and venous citrate plasma in patients with and without oral anticoagulation].
Schweizerische medizinische Wochenschrift 1998;128(44):1723-9.
1998: S Ravi; Thomas Mauron; Bernhard Lämmle; Walter A Wuillemin
Protein Z in healthy human individuals and in patients with a bleeding tendency.
British journal of haematology 1998;102(5):1219-23.
1998: Franziska Demarmels Biasiutti; Irmela Sulzer; B Stucki; Walter A Wuillemin; Miha Furlan; Bernhard Lämmle
Is plasminogen deficiency a thrombotic risk factor? A study on 23 thrombophilic patients and their family members.
Thrombosis and haemostasis 1998;80(1):167-70.
1998: Thomas Mauron; Bernhard Lämmle; Walter A Wuillemin
Influence of low molecular weight heparin and low molecular weight dextran sulfate on the inhibition of coagulation factor XIa by serpins.
Thrombosis and haemostasis 1998;80(1):82-6.
1998: Miha Furlan; Bernhard Lämmle
Deficiency of von Willebrand factor-cleaving protease in familial and acquired thrombotic thrombocytopenic purpura.
Baillière's clinical haematology 1998;11(2):509-14.
1998: Thomas Mauron; Iris Baumgartner; A Z'Brun; Franziska Demarmels Biasiutti; Maurice Redondo; D D Do; Bernhard Lämmle; Walter A Wuillemin
SimpliRED D-dimer assay: comparability of capillary and citrated venous whole blood, between-assay variability, and performance of the test for exclusion of deep vein thrombosis in symptomatic outpatients.
Thrombosis and haemostasis 1998;79(6):1217-9.
1998: Miha Furlan; Rodolfo Robles; Max Solenthaler; Bernhard Lämmle
Acquired deficiency of von Willebrand factor-cleaving protease in a patient with thrombotic thrombocytopenic purpura.
Blood 1998;91(8):2839-46.
1997: M Schloesser; Sacha Zeerleder; G Lutze; W M Halbmayer; S Hofferbert; Bernd Hinney; H Koestering; Bernhard Lämmle; G Pindur; K Thies; Michael Köhler; Wolfgang Engel
Mutations in the human factor XII gene.
Blood 1997;90(10):3967-77.
1997: Walter A Wuillemin; R Zenhäusern; M C Bernhard; Bernhard Lämmle
Phenprocoumon-induced hepatitis delaying precise diagnosis in a thrombophilic patient with activated protein C resistance due to factor V R506Q mutation.
The American journal of medicine 1997;103(5):437-9.
1997: M Züger; Franziska Demarmels Biasiutti; Walter A Wuillemin; Miha Furlan; Bernhard Lämmle
Subcutaneous low-molecular-weight heparin for treatment of Trousseau's syndrome.
Annals of hematology 1997;75(4):165-7.
1997: Einar Wilder-Smith; I Kothbauer-Margreiter; Bernhard Lämmle; Matthias Sturzenegger; Christoph Ozdoba; SP Hauser
Dural puncture and activated protein C resistance: risk factors for cerebral venous sinus thrombosis.
Journal of neurology, neurosurgery, and psychiatry 1997;63(3):351-6.
1997: Miha Furlan; Rodolfo Robles; Max Solenthaler; M Wassmer; P Sandoz; Bernhard Lämmle
Deficient activity of von Willebrand factor-cleaving protease in chronic relapsing thrombotic thrombocytopenic purpura.
Blood 1997;89(9):3097-103.
1997: Franziska Demarmels Biasiutti; B Stucki; Max Solenthaler; A Tobler; Miha Furlan; Bernhard Lämmle
Venous thrombosis after caesarean section in a young woman with homozygous APC resistance and type I protein S deficiency.
European journal of haematology 1997;58(2):127-9.
1997: Bernhard Lämmle; Franziska Demarmels Biasiutti; Walter A Wuillemin; B Stucki; Miha Furlan
[The significance of APC resistance (activated protein C) for clinical practice].
Praxis 1997;86(5):154-61.
1996: Miha Furlan; B Stucki; C Steinmann; M Jungo; Bernhard Lämmle
Normal binding of calcium to five fibrinogen variants with mutations in the carboxy terminal part of the gamma-chain.
Thrombosis and haemostasis 1996;76(3):377-83.
1996: Miha Furlan; C Steinmann; M Jungo; Bernhard Lämmle
Binding of calcium ions and their effect on clotting of fibrinogen Milano III, a variant with truncated A alpha-chains.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1996;7(3):331-5.
1996: C Steinmann; M Jungo; E A Beck; Bernhard Lämmle; Miha Furlan
Fibrinogen Claro--another dysfunctional fibrinogen variant with gamma 275 arginine-->histidine substitution.
Thrombosis research 1996;81(1):145-50.
1995: Franziska Demarmels Biasiutti; C Merlo; Miha Furlan; Irmela Sulzer; B R Binder; Bernhard Lämmle
No association of APC resistance with myocardial infarction.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1995;6(5):456-9.
1995: M Schloesser; S Hofferbert; U Bartz; G Lutze; Bernhard Lämmle; Wolfgang Engel
The novel acceptor splice site mutation 11396(G-->A) in the factor XII gene causes a truncated transcript in cross-reacting material negative patients.
Human molecular genetics 1995;4(7):1235-7.
1995: R Bühler; J K Hovinga; I Aebi-Huber; Miha Furlan; Bernhard Lämmle
Improved detection of proteolytically cleaved high molecular weight kininogen by immunoblotting using an antiserum against its reduced 47 kDa light chain.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1995;6(3):223-32.
1994: Miha Furlan; C Steinmann; M Jungo; C Bögli; Francesco Baudo; Rosaria Redaelli; F Fedeli; Bernhard Lämmle
A frameshift mutation in Exon V of the A alpha-chain gene leading to truncated A alpha-chains in the homozygous dysfibrinogen Milano III.
The Journal of biological chemistry 1994;269(52):33129-34.
1994: F D Biasiutti; Bernhard Lämmle
[Prevention of venous thromboembolism--in whom, when and how?].
Therapeutische Umschau. Revue thérapeutique 1994;51(10):663-70.
1994: C Steinmann; C Bögli; M Jungo; Bernhard Lämmle; G Heinemann; Bendicht Wermuth; Rosaria Redaelli; Francesco Baudo; Miha Furlan
A new substitution, gamma 358 Ser-->Cys, in fibrinogen Milano VII causes defective fibrin polymerization.
Blood 1994;84(6):1874-80.
1994: J K Hovinga; J Schaller; Hans Stricker; Walter A Wuillemin; Miha Furlan; Bernhard Lämmle
Coagulation factor XII Locarno: the functional defect is caused by the amino acid substitution Arg 353-->Pro leading to loss of a kallikrein cleavage site.
Blood 1994;84(4):1173-81.
1994: C Steinmann; C Bögli; M Jungo; Bernhard Lämmle; G Heinemann; Bendicht Wermuth; Rosaria Redaelli; Francesco Baudo; Miha Furlan
Fibrinogen Milano V: a congenital dysfibrinogenaemia with a gamma 275 Arg-->Cys substitution.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1994;5(4):463-71.
1994: H Bänninger; Bernhard Lämmle; Miha Furlan
Binding of alpha-thrombin to fibrin depends on the quality of the fibrin network.
The Biochemical journal 1994;298 ( Pt 1)():157-63.
1993: H Bänninger; T Hardegger; A Tobler; A Barth; P Schüpbach; W Reinhart; Bernhard Lämmle; M Furlan
Fibrin glue in surgery: frequent development of inhibitors of bovine thrombin and human factor V.
British journal of haematology 1993;85(3):528-32.
1993: C Steinmann; P Reber; M Jungo; Bernhard Lämmle; G Heinemann; Bendicht Wermuth; Miha Furlan
Fibrinogen Bern I: substitution gamma 337 Asn-->Lys is responsible for defective fibrin monomer polymerization.
Blood 1993;82(7):2104-8.
1993: Walter A Wuillemin; Miha Furlan; A von Felten; Bernhard Lämmle
Functional characterization of a variant prekallikrein (PK Zürich).
Thrombosis and haemostasis 1993;70(3):427-32.
1993: Bernhard Lämmle; T Hardegger; P W Straub; P Vock; M Furlan
[Internal bleeding in patients on oral anticoagulants].
Schweizerische medizinische Wochenschrift 1993;123(15):701-10.
1993: A Barth; M Furlan; Bernhard Lämmle
[Unexpectedly prolonged thrombin time].
Schweizerische medizinische Wochenschrift 1993;123(12):523-9.
1992: T Hardegger; Bernhard Lämmle
[Thromboembolic diseases from the hematologic viewpoint: 13 case examples].
Therapeutische Umschau. Revue thérapeutique 1992;49(12):859-66.
1992: Franziska Demarmels Biasiutti; Bernhard Lämmle
[Evaluating the origin of thrombophilia: indications and implementation].
Therapeutische Umschau. Revue thérapeutique 1992;49(12):850-8.
1992: Roland von Känel; Walter A Wuillemin; Miha Furlan; Bernhard Lämmle
Factor XII clotting activity and antigen levels in patients with thromboembolic disease.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1992;3(5):555-61.
1992: P Macherel; I Sulzer; M Furlan; Bernhard Lämmle
Determination of thrombin-antithrombin-III-complex is not a suitable screening test for detecting deficiency of protein C or protein S.
Thrombosis research 1992;66(6):775-7.
1992: Walter A Wuillemin; Miha Furlan; Hans Stricker; Bernhard Lämmle
Functional characterization of a variant factor XII (F XII Locarno) in a cross reacting material positive F XII deficient plasma.
Thrombosis and haemostasis 1992;67(2):219-25.
1991: Walter A Wuillemin; I Huber; Miha Furlan; Bernhard Lämmle
Functional characterization of an abnormal factor XII molecule (F XII Bern).
Blood 1991;78(4):997-1004.
1991: Miha Furlan; L Leupin; F D Biasiutti; Bernhard Lämmle
[Fibrinogen Bern III: a further case of hereditary fibrinogen variants with substitution A alpha 16 Arg----Cys].
Schweizerische medizinische Wochenschrift 1991;121(29):1068-71.
1991: Miha Furlan; R Robles; Bernhard Lämmle; J Zimmermann; E Hunziker
Immunogold labelling of human von Willebrand factor adsorbed to collagen.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1991;2(3):441-6.
1991: Walter A Wuillemin; Miha Furlan; I Huber; Bernhard Lämmle
Purified factor XII has a higher specific activity than the parent molecule in plasma.
Thrombosis and haemostasis 1991;65(2):169-73.
1991: Bernhard Lämmle; Walter A Wuillemin; I Huber; M Krauskopf; C Zürcher; R Pflugshaupt; Miha Furlan
Thromboembolism and bleeding tendency in congenital factor XII deficiency--a study on 74 subjects from 14 Swiss families.
Thrombosis and haemostasis 1991;65(2):117-21.
1991: Bernhard Lämmle; Henning Schneider
[Venous thromboembolism in pregnancy and puerperium: pathophysiology, therapy, prevention].
Archives of gynecology and obstetrics 1991;249 Suppl():S38-45.
1990: F Demarmels; Annette Ridolfi Lüthy; Andreas Hirt; Miha Furlan; Bernhard Lämmle
Inferior vena cava thrombosis in a child with nephroblastoma and combined deficiency of antithrombin III and free protein S.
Blut 1990;61(5):295-7.
1990: J K Hovinga; R Felix; Miha Furlan; Bernhard Lämmle
Malondialdehyde formation by blood platelets: a diagnostic test to assess acetylsalicylic acid induced thrombocytopathy?
Thrombosis research 1990;59(1):89-95.
1990: Walter A Wuillemin; Miha Furlan; Bernhard Lämmle
A quantitative dot immunobinding assay for coagulation factor XII in plasma.
Journal of immunological methods 1990;130(1):133-40.
1989: Miha Furlan; R Felix; N Escher; Bernhard Lämmle
How high is the true fibrinogen content of fibrinogen standards?
Thrombosis research 1989;56(5):583-92.
1989: Peter Bärtsch; Bernhard Lämmle; I Huber; André Haeberli; P Vock; O Oelz; P W Straub
Contact phase of blood coagulation is not activated in edema of high altitude.
Journal of applied physiology (Bethesda, Md. : 1985) 1989;67(4):1336-40.
1989: D Thommen; E Buhrfeind; R Felix; I Sulzer; Miha Furlan; Bernhard Lämmle
[Hemostasis parameters in 55 patients with venous and/or arterial thromboembolisms].
Schweizerische medizinische Wochenschrift 1989;119(16):493-9.
1989: Bernhard Lämmle; Miha Furlan; I Sulzer
[Comparison of a sensitive rabbit brain thromboplastin and a human placenta thromboplastin for thromboplastin time determination].
Schweizerische medizinische Wochenschrift 1989;119(6):178-83.
1988: Hans Stricker; Bernhard Lämmle; Miha Furlan; I Sulzer
Heparin-dependent in vitro aggregation of normal platelets by plasma of a patient with heparin-induced skin necrosis: specific diagnostic test for a rare side effect.
The American journal of medicine 1988;85(5):721-4.
1988: D Thommen; I Sulzer; E Buhrfeind; R Naef; Miha Furlan; Bernhard Lämmle
[Measurement of bleeding time and study of thrombocyte aggregation. Standardization of methods, normal values and results in patients with suspected hemorrhagic diathesis].
Schweizerische medizinische Wochenschrift 1988;118(43):1559-67.
1988: Miha Furlan; Bernhard Lämmle; A Aeberhard; E Kirste; Irmela Sulzer
Virus-inactivated factor VIII concentrate prevents postoperative bleeding in a patient with von Willebrand's disease.
Transfusion 1988;28(5):489-92.