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Aazdine Lamouri

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Catherine Gomez; Vincent Jarlier; Aazdine Lamouri; Alix Pantel; Prishila Ponien; Nawal Serradji; Guillaume Anquetin; Estelle Capton; Alexandra Aubry
Synthesis of gatifloxacin derivatives and their biological activities against Mycobacterium leprae and Mycobacterium tuberculosis.
Sarra Gam-Derouich; Aazdine Lamouri; François Maurel; Catherine Redeuilh; Yusuf Yagci; Gorkem Yilmaz; Selim Beyazıt; Benjamin Carbonnier; Philippe Decorse; Mohamed Chehimi
Diazonium salt-derived 4-(dimethylamino)phenyl groups as hydrogen donors in surface-confined radical photopolymerization for bioactive poly(2-hydroxyethyl methacrylate) grafts.
Ouardia Ait-Mohamed; Djebbar Atmani; Valentine Battisti; Christine Fahy; Lauriane Fritsch; Véronique Joliot; Aazdine Lamouri; Souhila Medjkane; Julien Pontis; Catherine Redeuilh; Mohamed Rholam; SLIMANE AIT-SI-ALI
Acetonic extract of Buxus sempervirens induces cell cycle arrest, apoptosis and autophagy in breast cancer cells.

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All Publications

2013: Catherine Gomez; Vincent Jarlier; Aazdine Lamouri; Alix Pantel; Prishila Ponien; Nawal Serradji; Guillaume Anquetin; Estelle Capton; Alexandra Aubry
Synthesis of gatifloxacin derivatives and their biological activities against Mycobacterium leprae and Mycobacterium tuberculosis.
Bioorganic & medicinal chemistry 2013;21(4):948-56.
2012: Sarra Gam-Derouich; Aazdine Lamouri; François Maurel; Catherine Redeuilh; Yusuf Yagci; Gorkem Yilmaz; Selim Beyazıt; Benjamin Carbonnier; Philippe Decorse; Mohamed Chehimi
Diazonium salt-derived 4-(dimethylamino)phenyl groups as hydrogen donors in surface-confined radical photopolymerization for bioactive poly(2-hydroxyethyl methacrylate) grafts.
Langmuir : the ACS journal of surfaces and colloids 2012;28(21):8035-45.
2011: Ouardia Ait-Mohamed; Djebbar Atmani; Valentine Battisti; Christine Fahy; Lauriane Fritsch; Véronique Joliot; Aazdine Lamouri; Souhila Medjkane; Julien Pontis; Catherine Redeuilh; Mohamed Rholam; SLIMANE AIT-SI-ALI
Acetonic extract of Buxus sempervirens induces cell cycle arrest, apoptosis and autophagy in breast cancer cells.
PloS one 2011;6(9):e24537.
2010: Nadia Meddad-Belhabich; Darina Aoun; Atimé Djimdé; Catherine Redeuilh; Georges Dive; France Massicot; François Chau; Françoise Heymans; Aazdine Lamouri
Design of new potent and selective secretory phospholipase A(2) inhibitors. 6-Synthesis, structure-activity relationships and molecular modelling of 1-substituted-4-[4,5-dihydro-1,2,4-(4H)-oxadiazol-5-one-3-yl(methyl)]-functionalized aryl piperazin/one/dione derivatives.
Bioorganic & medicinal chemistry 2010;18(10):3588-600.
2009: Marta Martins; Fernando Rodrigues-Lima; Julien Dairou; Aazdine Lamouri; Fabienne Malagnac; Philippe Silar; Jean-Marie Dupret
An acetyltransferase conferring tolerance to toxic aromatic amine chemicals: molecular and functional studies.
The Journal of biological chemistry 2009;284(28):18726-33.
2008: Latifa Boukli; Mohamed Touaibia; Nadia Meddad-Belhabich; Atimé Djimdé; Chang-Ha Park; Jung-Joo Kim; Joo-Hyoung Yoon; Aazdine Lamouri; Françoise Heymans
Design of new potent and selective secretory phospholipase A2 inhibitors. Part 5: synthesis and biological activity of 1-alkyl-4-[4,5-dihydro-1,2,4-[4H]-oxadiazol-5-one-3-ylmethylbenz-4'-yl(oyl)] piperazines.
Bioorganic & medicinal chemistry 2008;16(3):1242-53.
2007: Mohamed Touaibia; Atimé Djimdé; Fei Cao; Eric Boilard; Laboratoire Biochimie et Genie Enzymatique des Lipases; Gérard Lambeau; Catherine Redeuilh; Aazdine Lamouri; France Massicot; François Chau; Chang-Zhi Dong; Françoise Heymans
Inhibition of secreted phospholipase A2. 4-glycerol derivatives of 4,5-dihydro-3-(4-tetradecyloxybenzyl)-1,2,4-4H-oxadiazol-5-one with broad activities.
Journal of medicinal chemistry 2007;50(7):1618-26.
2006: Nawal Serradji; Okkacha Bensaid; Marc Martin; Wafa Sallem; Nathalie Dereuddre-Bosquet; Houcine Benmehdi; Catherine Redeuilh; Aazdine Lamouri; Georges Dive; Pascal Clayette; Françoise Heymans
Structure-activity relationships in platelet-activating factor. Part 13: synthesis and biological evaluation of piperazine derivatives with dual anti-PAF and anti-HIV-1 or pure antiretroviral activity.
Bioorganic & medicinal chemistry 2006;14(23):8109-25.
2005: Léon Assogba; Azali Ahamada-Himidi; Nadia Meddad-Bel Habich; Darina Aoun; Latifa Boukli; France Massicot; Carine M Mounier; Jack Huet; Aazdine Lamouri; Jean-Edouard Ombetta; Jean-Jacques Godfroid; Chang-Zhi Dong; Françoise Heymans
Inhibition of secretory phospholipase A2. 1-design, synthesis and structure-activity relationship studies starting from 4-tetradecyloxybenzamidine to obtain specific inhibitors of group II sPLA2s.
European journal of medicinal chemistry 2005;40(9):850-61.
2004: Nawal Serradji; Marc Martin; Okkacha Bensaid; salvatore cisternino; Christophe Rousselle; Nathalie Dereuddre-Bosquet; Jack Huet; Catherine Redeuilh; Aazdine Lamouri; Chang-Zhi Dong; Pascal Clayette; Jean-Michel Scherrmann; Dominique Dormont; Françoise Heymans
Structure-activity relationships in platelet-activating factor. 12. Synthesis and biological evaluation of platelet-activating factor antagonists with anti-HIV-1 activity.
Journal of medicinal chemistry 2004;47(25):6410-9.
2000: Marc Martin; Nawal Serradji; Nathalie Dereuddre-Bosquet; Gwenaelle Le Pavec; G Fichet; Aazdine Lamouri; Françoise Heymans; Jean-Jacques Godfroid; Pascal Clayette; Dominique Dormont
PMS-601, a new platelet-activating factor receptor antagonist that inhibits human immunodeficiency virus replication and potentiates zidovudine activity in macrophages.
Antimicrobial agents and chemotherapy 2000;44(11):3150-4.
2000: Marc Martin; Nawal Serradji; Nathalie Dereuddre-Bosquet; O Bensaïd; G Fichet; Aazdine Lamouri; Françoise Heymans; Pascal Clayette; Jean-Jacques Godfroid; Dominique Dormont
[Antiretroviral ant anti-inflammatory properties of a novel platelet activation factor antagonist, PMS-601].
Pathologie-biologie 2000;48(5):513-9.
2000: Nawal Serradji; Okkacha Bensaid; Marc Martin; E Kan; Nathalie Dereuddre-Bosquet; Catherine Redeuilh; Jack Huet; Françoise Heymans; Aazdine Lamouri; Pascal Clayette; Chang-Zhi Dong; Dominique Dormont; Jean-Jacques Godfroid
Structure-activity relationships in platelet-activating factor (PAF). 10. From PAF antagonism to inhibition of HIV-1 replication.
Journal of medicinal chemistry 2000;43(11):2149-54.
1999: A Pelé-Tounian; S L Chan; F Rondu; G Le Bihan; Marie-Hélène Giroix; Aazdine Lamouri; E Touboul; Bruno Pfeiffer; Dominique Manechez; Pierre Renard; B Guardiola-Lemaître; Jean-Jacques Godfroid; Luc Pénicaud; N G Morgan; Alain Ktorza
Effect of the new imidazoline derivative S-22068 (PMS 847) on insulin secretion in vitro and glucose turnover in vivo in rats.
European journal of pharmacology 1999;377(1):81-7.
1999: G Le Bihan; F Rondu; A Pelé-Tounian; X Wang; S Lidy; E Touboul; Aazdine Lamouri; Georges Dive; Jack Huet; Bruno Pfeiffer; Pierre Renard; B Guardiola-Lemaître; D Manéchez; Luc Pénicaud; Alain Ktorza; Jean-Jacques Godfroid
Design and synthesis of imidazoline derivatives active on glucose homeostasis in a rat model of type II diabetes. 2. Syntheses and biological activities of 1,4-dialkyl-, 1,4-dibenzyl, and 1-benzyl-4-alkyl-2-(4',5'-dihydro-1'H-imidazol-2'-yl)piperazines and isosteric analogues of imidazoline.
Journal of medicinal chemistry 1999;42(9):1587-603.
1998: A Pelé-Tounian; X Wang; F Rondu; Aazdine Lamouri; E Touboul; S Marc; R Dokhan; Bruno Pfeiffer; Dominique Manechez; Pierre Renard; B Guardiola-Lemaître; Jean-Jacques Godfroid; Luc Pénicaud; Alain Ktorza
Potent antihyperglycaemic property of a new imidazoline derivative S-22068 (PMS 847) in a rat model of NIDDM.
British journal of pharmacology 1998;124(8):1591-6.
1997: F Rondu; G Le Bihan; X Wang; Aazdine Lamouri; E Touboul; Georges Dive; T Bellahsene; Bruno Pfeiffer; Pierre Renard; B Guardiola-Lemaitre; Dominique Manechez; L Penicaud; Alain Ktorza; Jean-Jacques Godfroid
Design and synthesis of imidazoline derivatives active on glucose homeostasis in a rat model of type II diabetes. 1. Synthesis and biological activities of N-benzyl-N'-(arylalkyl)-2-(4',5'-dihydro-1'H-imidazol-2'-yl)piperazines .
Journal of medicinal chemistry 1997;40(23):3793-803.
1997: France Massicot; Aazdine Lamouri; Chantal Martin; Chuong Pham-Huy; Françoise Heymans; Jean-Michel Warnet; Jean-Jacques Godfroid; Jean-Roger Claude
Preventive effects of two PAF-antagonists, PMS 536 and PMS 549, on cyclosporin-induced LLC-PK1 oxidative injury.
Journal of lipid mediators and cell signalling 1997;15(2):203-14.
1997: Françoise Heymans; Georges Dive; Aazdine Lamouri; T Bellahsene; E Touboul; Jack Huet; F Tavet; Catherine Redeuilh; Jean-Jacques Godfroid
Design and modeling of new platelet-activating factor antagonists. 3. Relative importance of hydrophobicity and electronic distribution in piperazinic series.
Journal of lipid mediators and cell signalling 1997;15(2):161-73.
1997: F Tavet; Aazdine Lamouri; Françoise Heymans; Georges Dive; E Touboul; N Blavet; Jean-Jacques Godfroid
Design and modeling of new platelet-activating factor antagonists. 2. Synthesis and biological activity of 1,4-bis-(3',4',5'-trimethoxybenzoyl)-2-alkyl and 2-alkyloxymethylpiperazines.
Journal of lipid mediators and cell signalling 1997;15(2):145-59.
1996: X Wang; F Rondu; Aazdine Lamouri; R Dokhan; S Marc; E Touboul; Bruno Pfeiffer; Dominique Manechez; Pierre Renard; B Guardiola-Lemaitre; Jean-Jacques Godfroid; Alain Ktorza; Luc Pénicaud
Effect of S-21663 (PMS 812), an imidazoline derivative, on glucose tolerance and insulin secretion in a rat model of type II diabetes.
The Journal of pharmacology and experimental therapeutics 1996;278(1):82-9.
1993: Aazdine Lamouri; Françoise Heymans; F Tavet; Georges Dive; J P Batt; N Blavet; P Braquet; Jean-Jacques Godfroid
Design and modeling of new platelet-activating factor antagonists. 1. Synthesis and biological activity of 1,4-bis(3',4',5'-trimethoxybenzoyl)-2-[[(substituted carbonyl and carbamoyl)oxy]methyl]piperazines.
Journal of medicinal chemistry 1993;36(8):990-1000.
1991: Josette Lamotte-Brasseur; Françoise Heymans; Georges Dive; Aazdine Lamouri; J P Batt; C Redeuilh; D Hosford; P Braquet; Jean-Jacques Godfroid
PAF receptor and "Cache-oreilles" effect. Simple PAF antagonists.
Lipids 1991;26(12):1167-71.
1991: J P Batt; Aazdine Lamouri; F Tavet; Françoise Heymans; Georges Dive; Jean-Jacques Godfroid
New hypothesis on the conformation of the PAF-receptor from studies on the geometry of selected platelet-activating factor-antagonists.
Journal of lipid mediators 1991;4(3):343-6.
1991: Josette Lamotte-Brasseur; Georges Dive; Aazdine Lamouri; Françoise Heymans; Jean-Jacques Godfroid
PAF-receptor. III. Conformational and electronic properties of PAF-like agonists and antagonists.
Biochimica et biophysica acta 1991;1085(1):91-105.
1991: J B Stensland; J P Batt; Aazdine Lamouri; Jean-Jacques Godfroid
Platelet activating factor antagonists. Structure of N,N'-bis(3,4,5-trimethoxybenzoyl)-2-piperazinylmethyl 2,2-dimethylpropanoate.
Acta crystallographica. Section C, Crystal structure communications 1991;47 ( Pt 7)():1453-7.