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Robert Landick

Research Profile

Chemicals & Drugs

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Escherichia coli

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Genes & Molecular Sequences

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Publications

TOP 3
Albert Weixlbaumer; Robert Landick; Katherine Leon; Seth A Darst
Structural basis of transcriptional pausing in bacteria.
Jason M Peters; Frances Tran; Jeffrey A Grass; Erik D Jessen; Rachel A Mooney; Robert Landick
Rho and NusG suppress pervasive antisense transcription in Escherichia coli.
Daniel J Koslover; Robert Landick; Rachel A Mooney; Furqan M Fazal; Steven M Block
Binding and translocation of termination factor rho studied at the single-molecule level.

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All Publications

2013: Albert Weixlbaumer; Robert Landick; Katherine Leon; Seth A Darst
Structural basis of transcriptional pausing in bacteria.
Cell 2013;152(3):431-41.
2012: Jason M Peters; Frances Tran; Jeffrey A Grass; Erik D Jessen; Rachel A Mooney; Robert Landick
Rho and NusG suppress pervasive antisense transcription in Escherichia coli.
Genes & development 2012;26(23):2621-33.
2012: Daniel J Koslover; Robert Landick; Rachel A Mooney; Furqan M Fazal; Steven M Block
Binding and translocation of termination factor rho studied at the single-molecule level.
Journal of molecular biology 2012;423(5):664-76.
2012: Björn M Burmann; Stefan H Knauer; Robert Landick; Rachel A Mooney; Kristian Schweimer; Anastasiya Sevostyanova; Irina Artsimovitch; Paul Rösch
An α helix to β barrel domain switch transforms the transcription factor RfaH into a translation factor.
Cell 2012;150(2):291-303.
2012: Murali Palangat; Steven M Block; Matthew H Larson; Averell Gnatt; Xiaopeng Hu; Robert Landick
Efficient reconstitution of transcription elongation complexes for single-molecule studies of eukaryotic RNA polymerase II.
Transcription 2012;3(3):146-53.
2012: Michael S Schwalbach; Mary Tremaine; Yaoping Zhang; Wesley D Marner; Jennifer L Reed; Venkatesh Balan; William Bothfeld; Cameron Cotten; Leonardo da Costa Sousa; Bruce Dale; James Ellinger; Jeffrey A Grass; Alan Higbee; Mingjie Jin; David H Keating; Patricia J Kiley; Robert Landick
Complex physiology and compound stress responses during fermentation of alkali-pretreated corn stover hydrolysate by an Escherichia coli ethanologen.
Applied and environmental microbiology 2012;78(9):3442-57.
2012: Matthew H Larson; Murali Palangat; Jing Zhou; Craig D Kaplan; Roger D Kornberg; Robert Landick; Steven M Block
Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(17):6555-60.
2012: Richard L Gourse; Robert Landick
CoSMoS unravels mysteries of transcription initiation.
Cell 2012;148(4):635-7.
2011: Jing Zhou; Kook Sun Ha; Arthur La Porta; Robert Landick; Steven M Block
Applied force provides insight into transcriptional pausing and its modulation by transcription factor NusA.
Molecular cell 2011;44(4):635-46.
2011: Jason M Peters; Abbey D Vangeloff; Robert Landick
Bacterial transcription terminators: the RNA 3'-end chronicles.
Journal of molecular biology 2011;412(5):793-813.
2011: Pyae P Hein; Murali Palangat; Robert Landick
RNA transcript 3'-proximal sequence affects translocation bias of RNA polymerase.
Biochemistry 2011;50(32):7002-14.
2011: Murali Palangat; Marie-France Langelier; Benoit Coulombe; Jeffrey A Grass; Robert Landick
The RPB2 flap loop of human RNA polymerase II is dispensable for transcription initiation and elongation.
Molecular and cellular biology 2011;31(16):3312-25.
2011: Anastasiya Sevostyanova; Georgiy A Belogurov; Robert Landick; Rachel A Mooney; Irina Artsimovitch
The β subunit gate loop is required for RNA polymerase modification by RfaH and NusG.
Molecular cell 2011;43(2):253-62.
2011: Matthew H Larson; Robert Landick; Steven M Block
Single-molecule studies of RNA polymerase: one singular sensation, every little step it takes.
Molecular cell 2011;41(3):249-62.
2011: Sarah E Davis; Rachel A Mooney; Elenita I Kanin; Jeff Grass; Robert Landick; Aseem Z Ansari
Mapping E. coli RNA polymerase and associated transcription factors and identifying promoters genome-wide.
Methods in enzymology 2011;498():449-71.
2010: Tom M Conrad; Michael Frazier; Andrew R Joyce; Byung-Kwan Cho; Eric M Knight; Nathan E Lewis; Robert Landick; Bernhard Ø Palsson
RNA polymerase mutants found through adaptive evolution reprogram Escherichia coli for optimal growth in minimal media.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(47):20500-5.
2010: Jason Huff; Agata Czyz; Robert Landick; Michael Niederweis
Taking phage integration to the next level as a genetic tool for mycobacteria.
Gene 2010;468(1-2):8-19.
2010: Kook Sun Ha; Innokenti Toulokhonov; Dmitry G Vassylyev; Robert Landick
The NusA N-terminal domain is necessary and sufficient for enhancement of transcriptional pausing via interaction with the RNA exit channel of RNA polymerase.
Journal of molecular biology 2010;401(5):708-25.
2010: Susan E Cohen; Cindi A Lewis; Rachel A Mooney; Michael A Kohanski; James J Collins; Robert Landick; Graham C Walker
Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(35):15517-22.
2010: Kristina M Herbert; Jing Zhou; Rachel A Mooney; Arthur La Porta; Robert Landick; Steven M Block
E. coli NusG inhibits backtracking and accelerates pause-free transcription by promoting forward translocation of RNA polymerase.
Journal of molecular biology 2010;399(1):17-30.
2010: Pyae P Hein; Robert Landick
The bridge helix coordinates movements of modules in RNA polymerase.
BMC biology 2010;8():141.
2010: Natacha Opalka; Jesse Brown; William J Lane; Kelly-Anne F Twist; Robert Landick; Francisco J Asturias; Seth A Darst
Complete structural model of Escherichia coli RNA polymerase from a hybrid approach.
PLoS biology 2010;8(9):.
2010: Jinwei Zhang; Murali Palangat; Robert Landick
Role of the RNA polymerase trigger loop in catalysis and pausing.
Nature structural & molecular biology 2010;17(1):99-104.
2009: Jason M Peters; Rachel A Mooney; Pei-Fen Kuan; Jennifer L Rowland; Sündüz Keles; Robert Landick
Rho directs widespread termination of intragenic and stable RNA transcription.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(36):15406-11.
2009: Rachel Anne Mooney; Kristian Schweimer; Paul Rösch; Max Gottesman; Robert Landick
Two structurally independent domains of E. coli NusG create regulatory plasticity via distinct interactions with RNA polymerase and regulators.
Journal of molecular biology 2009;391(2):341-58.
2009: Robert Landick
Transcriptional pausing without backtracking.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(22):8797-8.
2009: Robert Landick
Functional divergence in the growing family of RNA polymerases.
Structure (London, England : 1993) 2009;17(3):323-5.
2009: Georgiy A Belogurov; Rachel A Mooney; Vladimir Svetlov; Robert Landick; Irina Artsimovitch
Functional specialization of transcription elongation factors.
The EMBO journal 2009;28(2):112-22.
2009: Rachel A Mooney; Sarah E Davis; Jason M Peters; Jennifer L Rowland; Aseem Z Ansari; Robert Landick
Regulator trafficking on bacterial transcription units in vivo.
Molecular cell 2009;33(1):97-108.
2008: Yann S Dufour; Robert Landick; Timothy J Donohue
Organization and evolution of the biological response to singlet oxygen stress.
Journal of molecular biology 2008;383(3):713-30.
2008: Matthew H Larson; William J Greenleaf; Robert Landick; Steven M Block
Applied force reveals mechanistic and energetic details of transcription termination.
Cell 2008;132(6):971-82.
2008: Lars F Westblade; Leonid Minakhin; Konstantin Kuznedelov; Alan J Tackett; Emmanuel J Chang; Rachel A Mooney; Irina Vvedenskaya; Qing Jun Wang; David Fenyö; Michael P Rout; Robert Landick; Brian T Chait; Konstantin Severinov; Seth A Darst
Rapid isolation and identification of bacteriophage T4-encoded modifications of Escherichia coli RNA polymerase: a generic method to study bacteriophage/host interactions.
Journal of proteome research 2008;7(3):1244-50.
2007: Innokenti Toulokhonov; Jinwei Zhang; Murali Palangat; Robert Landick
A central role of the RNA polymerase trigger loop in active-site rearrangement during transcriptional pausing.
Molecular cell 2007;27(3):406-19.
2007: Dmitry G Vassylyev; Marina N Vassylyeva; Jinwei Zhang; Murali Palangat; Irina Artsimovitch; Robert Landick
Structural basis for substrate loading in bacterial RNA polymerase.
Nature 2007;448(7150):163-8.
2007: Scotty Kyzer; Kook Sun Ha; Robert Landick; Murali Palangat
Direct versus limited-step reconstitution reveals key features of an RNA hairpin-stabilized paused transcription complex.
The Journal of biological chemistry 2007;282(26):19020-8.
2007: Caroline Davis; Craig A Bingman; Robert Landick; M Thomas Record; Ruth M Saecker
Real-time footprinting of DNA in the first kinetically significant intermediate in open complex formation by Escherichia coli RNA polymerase.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(19):7833-8.
2006: Robert Landick
A long time in the making--the Nobel Prize for RNA polymerase.
Cell 2006;127(6):1087-90.
2006: Innokenti Toulokhonov; Robert Landick
The role of the lid element in transcription by E. coli RNA polymerase.
Journal of molecular biology 2006;361(4):644-58.
2006: Ravindra V Dalal; Matthew H Larson; Keir C Neuman; Jeff Gelles; Robert Landick; Steven M Block
Pulling on the nascent RNA during transcription does not alter kinetics of elongation or ubiquitous pausing.
Molecular cell 2006;23(2):231-9.
2006: Kristina M Herbert; Arthur La Porta; Becky J Wong; Rachel A Mooney; Keir C Neuman; Robert Landick; Steven M Block
Sequence-resolved detection of pausing by single RNA polymerase molecules.
Cell 2006;125(6):1083-94.
2006: Josefine Ederth; Rachel A Mooney; Leif A Isaksson; Robert Landick
Functional interplay between the jaw domain of bacterial RNA polymerase and allele-specific residues in the product RNA-binding pocket.
Journal of molecular biology 2006;356(5):1163-79.
2005: Robert Landick
NTP-entry routes in multi-subunit RNA polymerases.
Trends in biochemical sciences 2005;30(12):651-4.
2005: Elio A Abbondanzieri; William J Greenleaf; Joshua W Shaevitz; Robert Landick; Steven M Block
Direct observation of base-pair stepping by RNA polymerase.
Nature 2005;438(7067):460-5.
2005: Rachel Anne Mooney; Seth A Darst; Robert Landick
Sigma and RNA polymerase: an on-again, off-again relationship?
Molecular cell 2005;20(3):335-45.
2005: Murali Palangat; Dan B Renner; David H Price; Robert Landick
A negative elongation factor for human RNA polymerase II inhibits the anti-arrest transcript-cleavage factor TFIIS.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(42):15036-41.
2005: Christopher D Herring; Marni Raffaelle; Timothy Allen; Elenita I Kanin; Robert Landick; Aseem Z Ansari; Bernhard Ø Palsson
Immobilization of Escherichia coli RNA polymerase and location of binding sites by use of chromatin immunoprecipitation and microarrays.
Journal of bacteriology 2005;187(17):6166-74.
2005: Scotty Kyzer; Jinwei Zhang; Robert Landick
Inhibition of RNA polymerase by streptolydigin: no cycling allowed.
Cell 2005;122(4):494-6.
2004: Kati Geszvain; Tanja M Gruber; Rachel Anne Mooney; Carol A Gross; Robert Landick
A hydrophobic patch on the flap-tip helix of E.coli RNA polymerase mediates sigma(70) region 4 function.
Journal of molecular biology 2004;343(3):569-87.
2004: Murali Palangat; Christopher T Hittinger; Robert Landick
Downstream DNA selectively affects a paused conformation of human RNA polymerase II.
Journal of molecular biology 2004;341(2):429-42.
2004: Robert Landick
Active-site dynamics in RNA polymerases.
Cell 2004;116(3):351-3.
2004: Simon F Tolić-Nørrelykke; Anita M Engh; Robert Landick; Jeff Gelles
Diversity in the rates of transcript elongation by single RNA polymerase molecules.
The Journal of biological chemistry 2004;279(5):3292-9.
2003: Joshua W Shaevitz; Elio A Abbondanzieri; Robert Landick; Steven M Block
Backtracking by single RNA polymerase molecules observed at near-base-pair resolution.
Nature 2003;426(6967):684-7.
2003: Rachel Anne Mooney; Robert Landick
Tethering sigma70 to RNA polymerase reveals high in vivo activity of sigma factors and sigma70-dependent pausing at promoter-distal locations.
Genes & development 2003;17(22):2839-51.
2003: Keir C Neuman; Elio A Abbondanzieri; Robert Landick; Jeff Gelles; Steven M Block
Ubiquitous transcriptional pausing is independent of RNA polymerase backtracking.
Cell 2003;115(4):437-47.
2003: Innokenti Toulokhonov; Robert Landick
The flap domain is required for pause RNA hairpin inhibition of catalysis by RNA polymerase and can modulate intrinsic termination.
Molecular cell 2003;12(5):1125-36.
2003: Irina Artsimovitch; Clement Chu; A Simon Lynch; Robert Landick
A new class of bacterial RNA polymerase inhibitor affects nucleotide addition.
Science (New York, N.Y.) 2003;302(5645):650-4.
2003: Kelly-Anne Wilson; Markus Kalkum; Jennifer Ottesen; Julia Yuzenkova; Brian T Chait; Robert Landick; Tom Muir; Konstantin Severinov; Seth A Darst
Structure of microcin J25, a peptide inhibitor of bacterial RNA polymerase, is a lassoed tail.
Journal of the American Chemical Society 2003;125(41):12475-83.
2003: Thomas J Santangelo; Rachel Anne Mooney; Robert Landick; Jeffrey W Roberts
RNA polymerase mutations that impair conversion to a termination-resistant complex by Q antiterminator proteins.
Genes & development 2003;17(10):1281-92.
2003: Irina Artsimovitch; Vladimir Svetlov; Katsuhiko S Murakami; Robert Landick
Co-overexpression of Escherichia coli RNA polymerase subunits allows isolation and analysis of mutant enzymes lacking lineage-specific sequence insertions.
The Journal of biological chemistry 2003;278(14):12344-55.
2002: Julia Yuzenkova; Monica Delgado; Sergei Nechaev; Dhruti Savalia; Vitaly Epshtein; Irina Artsimovitch; Rachel A Mooney; Robert Landick; Ricardo N Farias; Raul Salomon; Konstantin Severinov
Mutations of bacterial RNA polymerase leading to resistance to microcin j25.
The Journal of biological chemistry 2002;277(52):50867-75.
2002: Josefine Ederth; Irina Artsimovitch; Leif A Isaksson; Robert Landick
The downstream DNA jaw of bacterial RNA polymerase facilitates both transcriptional initiation and pausing.
The Journal of biological chemistry 2002;277(40):37456-63.
2002: Irina Artsimovitch; Robert Landick
The transcriptional regulator RfaH stimulates RNA chain synthesis after recruitment to elongation complexes by the exposed nontemplate DNA strand.
Cell 2002;109(2):193-203.
2001: Murali Palangat; Robert Landick
Roles of RNA:DNA hybrid stability, RNA structure, and active site conformation in pausing by human RNA polymerase II.
Journal of molecular biology 2001;311(2):265-82.
2001: Tanja M Gruber; D Markov; Meghan M. Sharp; Brian A Young; Chi Zen Lu; Hong Ji Zhong; Irina Artsimovitch; Kati Geszvain; Terrance M Arthur; Richard R Burgess; Robert Landick; K Severinov; Carol A Gross
Binding of the initiation factor sigma(70) to core RNA polymerase is a multistep process.
Molecular cell 2001;8(1):21-31.
2001: Robert Landick
RNA polymerase clamps down.
Cell 2001;105(5):567-70.
2001: Innokenti Toulokhonov; Irina Artsimovitch; Robert Landick
Allosteric control of RNA polymerase by a site that contacts nascent RNA hairpins.
Science (New York, N.Y.) 2001;292(5517):730-3.
2000: Irina Artsimovitch; Vladimir Svetlov; Larry C Anthony; Richard R Burgess; Robert Landick
RNA polymerases from Bacillus subtilis and Escherichia coli differ in recognition of regulatory signals in vitro.
Journal of bacteriology 2000;182(21):6027-35.
2000: Larry C Anthony; Irina Artsimovitch; Vladimir Svetlov; Robert Landick; Richard R Burgess
Rapid purification of His(6)-tagged Bacillus subtilis core RNA polymerase.
Protein expression and purification 2000;19(3):350-4.
2000: Irina Artsimovitch; Robert Landick
Pausing by bacterial RNA polymerase is mediated by mechanistically distinct classes of signals.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(13):7090-5.
2000: Natacha Opalka; R A Mooney; Catherine Richter; Konstantin Severinov; Robert Landick; Seth A Darst
Direct localization of a beta-subunit domain on the three-dimensional structure of Escherichia coli RNA polymerase.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(2):617-22.
1999: H Yin; Irina Artsimovitch; Robert Landick; Jeff Gelles
Nonequilibrium mechanism of transcription termination from observations of single RNA polymerase molecules.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(23):13124-9.
1999: R A Mooney; Robert Landick
RNA polymerase unveiled.
Cell 1999;98(6):687-90.
1999: Tao Pan; Irina Artsimovitch; Xing-Wang Fang; Robert Landick; Tobin R Sosnick
Folding of a large ribozyme during transcription and the effect of the elongation factor NusA.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(17):9545-50.
1999: R G Keene; A Mueller; Robert Landick; L London
Transcriptional pause, arrest and termination sites for RNA polymerase II in mammalian N- and c-myc genes.
Nucleic acids research 1999;27(15):3173-82.
1999: Robert Landick
Shifting RNA polymerase into overdrive.
Science (New York, N.Y.) 1999;284(5414):598-9.
1998: M D Wang; Mark J Schnitzer; H Yin; Robert Landick; Jeff Gelles; Steven M Block
Force and velocity measured for single molecules of RNA polymerase.
Science (New York, N.Y.) 1998;282(5390):902-7.
1998: Irina Artsimovitch; Robert Landick
Interaction of a nascent RNA structure with RNA polymerase is required for hairpin-dependent transcriptional pausing but not for transcript release.
Genes & development 1998;12(19):3110-22.
1998: R A Mooney; Irina Artsimovitch; Robert Landick
Information processing by RNA polymerase: recognition of regulatory signals during RNA chain elongation.
Journal of bacteriology 1998;180(13):3265-75.
1998: Murali Palangat; T I Meier; R G Keene; Robert Landick
Transcriptional pausing at +62 of the HIV-1 nascent RNA modulates formation of the TAR RNA structure.
Molecular cell 1998;1(7):1033-42.
1998: Jeff Gelles; Robert Landick
RNA polymerase as a molecular motor.
Cell 1998;93(1):13-6.
1997: Konstantin Severinov; R Mooney; Seth A Darst; Robert Landick
Tethering of the large subunits of Escherichia coli RNA polymerase.
The Journal of biological chemistry 1997;272(39):24137-40.
1997: Robert Landick
RNA polymerase slides home: pause and termination site recognition.
Cell 1997;88(6):741-4.
1997: M D Wang; H Yin; Robert Landick; Jeff Gelles; Steven M Block
Stretching DNA with optical tweezers.
Biophysical journal 1997;72(3):1335-46.
1996: P L Tavormina; Robert Landick; Carol A Gross
Isolation, purification, and in vitro characterization of recessive-lethal-mutant RNA polymerases from Escherichia coli.
Journal of bacteriology 1996;178(17):5263-71.
1996: Robert Landick; J W Roberts
The shrewd grasp of RNA polymerase.
Science (New York, N.Y.) 1996;273(5272):202-3.
1996: L M Heisler; G Feng; D J Jin; Carol A Gross; Robert Landick
Amino acid substitutions in the two largest subunits of Escherichia coli RNA polymerase that suppress a defective Rho termination factor affect different parts of the transcription complex.
The Journal of biological chemistry 1996;271(24):14572-83.
1995: H Yin; M D Wang; K Svoboda; Robert Landick; Steven M Block; Jeff Gelles
Transcription against an applied force.
Science (New York, N.Y.) 1995;270(5242):1653-7.
1995: D Wang; T I Meier; C L Chan; G Feng; D N Lee; Robert Landick
Discontinuous movements of DNA and RNA in RNA polymerase accompany formation of a paused transcription complex.
Cell 1995;81(3):341-50.
1995: Jeff Gelles; H Yin; L Finzi; O K Wong; Robert Landick
Single-molecule kinetic studies on DNA transcription and transcriptional regulation.
Biophysical journal 1995;68(4 Suppl):73S.
1994: H Yin; Robert Landick; Jeff Gelles
Tethered particle motion method for studying transcript elongation by a single RNA polymerase molecule.
Biophysical journal 1994;67(6):2468-78.
1994: R Weilbaecher; C Hebron; G Feng; Robert Landick
Termination-altering amino acid substitutions in the beta' subunit of Escherichia coli RNA polymerase identify regions involved in RNA chain elongation.
Genes & development 1994;8(23):2913-27.
1994: D N Lee; G Feng; Robert Landick
GreA-induced transcript cleavage is accompanied by reverse translocation to a different transcription complex conformation.
The Journal of biological chemistry 1994;269(35):22295-303.
1994: G H Feng; D N Lee; D Wang; C L Chan; Robert Landick
GreA-induced transcript cleavage in transcription complexes containing Escherichia coli RNA polymerase is controlled by multiple factors, including nascent transcript location and structure.
The Journal of biological chemistry 1994;269(35):22282-94.
1993: L M Heisler; H Suzuki; Robert Landick; Carol A Gross
Four contiguous amino acids define the target for streptolydigin resistance in the beta subunit of Escherichia coli RNA polymerase.
The Journal of biological chemistry 1993;268(34):25369-75.
1993: C L Chan; Robert Landick
Dissection of the his leader pause site by base substitution reveals a multipartite signal that includes a pause RNA hairpin.
Journal of molecular biology 1993;233(1):25-42.
1992: D N Lee; Robert Landick
Structure of RNA and DNA chains in paused transcription complexes containing Escherichia coli RNA polymerase.
Journal of molecular biology 1992;228(3):759-77.
1991: L London; R G Keene; Robert Landick
Analysis of premature termination in c-myc during transcription by RNA polymerase II in a HeLa nuclear extract.
Molecular and cellular biology 1991;11(9):4599-615.
1990: Robert Landick; C Yanofsky; K Choo; L Phung
Replacement of the Escherichia coli trp operon attenuation control codons alters operon expression.
Journal of molecular biology 1990;216(1):25-37.
1990: D N Lee; L Phung; J Stewart; Robert Landick
Transcription pausing by Escherichia coli RNA polymerase is modulated by downstream DNA sequences.
The Journal of biological chemistry 1990;265(25):15145-53.
1990: Robert Landick; J Stewart; D N Lee
Amino acid changes in conserved regions of the beta-subunit of Escherichia coli RNA polymerase alter transcription pausing and termination.
Genes & development 1990;4(9):1623-36.
1990: Robert Landick; A Colwell; J Stewart
Insertional mutagenesis of a plasmid-borne Escherichia coli rpoB gene reveals alterations that inhibit beta-subunit assembly into RNA polymerase.
Journal of bacteriology 1990;172(6):2844-54.
1989: C L Chan; Robert Landick
The Salmonella typhimurium his operon leader region contains an RNA hairpin-dependent transcription pause site. Mechanistic implications of the effect on pausing of altered RNA hairpins.
The Journal of biological chemistry 1989;264(34):20796-804.