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Arthur Landy

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Physiology

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Genes & Molecular Sequences

Cruciform DNA

Phenomena

Protein Binding

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Co-Publications
Name
16
Nunes-Düby, Simone
12
Ellenberger, Tom
9
Radman-Livaja, Marta
8
Tirumalai, Radhakrishna
6
Aihara, Hideki
6
Biswas, Tapan
6
Lee, Sang Yeol
4
Kwon, Hyock Joo
4
Azaro, Marco
4
Warren, David
4
Sarkar, Dibyendu
3
Weisberg, Robert
2
Wojciak, Jonathan
2
Mierke, Dale
2
Hazelbaker, Dane

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Publications

TOP 3
Warren David; Laxmikanthan Gurunathan; Landy Arthur
A chimeric Cre recombinase with regulated directionality.
Hazelbaker Dane; Azaro Marco A; Landy Arthur
A biotin interference assay highlights two different asymmetric interaction profiles for lambda integrase arm-type binding sites in integrative versus excisive recombination.
Sun Xingmin; Mierke Dale F; Biswas Tapan; Lee Sang Yeol; Landy Arthur; Radman-Livaja Marta
Architecture of the 99 bp DNA-six-protein regulatory complex of the lambda att site.

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All Publications

2008: Warren David; Laxmikanthan Gurunathan; Landy Arthur
A chimeric Cre recombinase with regulated directionality.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(47):18278-83.
2008: Hazelbaker Dane; Azaro Marco A; Landy Arthur
A biotin interference assay highlights two different asymmetric interaction profiles for lambda integrase arm-type binding sites in integrative versus excisive recombination.
The Journal of biological chemistry 2008;283(18):12402-14.
2006: Sun Xingmin; Mierke Dale F; Biswas Tapan; Lee Sang Yeol; Landy Arthur; Radman-Livaja Marta
Architecture of the 99 bp DNA-six-protein regulatory complex of the lambda att site.
Molecular cell 2006;24(4):569-80.
2006: Mumm Jeffrey P; Landy Arthur; Gelles Jeff
Viewing single lambda site-specific recombination events from start to finish.
The EMBO journal 2006;25(19):4586-95.
2006: Radman-Livaja Marta; Biswas Tapan; Ellenberger Tom; Landy Arthur; Aihara Hideki
DNA arms do the legwork to ensure the directionality of lambda site-specific recombination.
Current opinion in structural biology 2006;16(1):42-50.
2005: Hazelbaker Dane; Radman-Livaja Marta; Landy Arthur
Receipt of the C-terminal tail from a neighboring lambda Int protomer allosterically stimulates Holliday junction resolution.
Journal of molecular biology 2005;351(5):948-55.
2005: Biswas Tapan; Aihara Hideki; Radman-Livaja Marta; Filman David; Landy Arthur; Ellenberger Tom
A structural basis for allosteric control of DNA recombination by lambda integrase.
Nature 2005;435(7045):1059-66.
2005: Radman-Livaja Marta; Biswas Tapan; Mierke Dale; Landy Arthur
Architecture of recombination intermediates visualized by in-gel FRET of lambda integrase-Holliday junction-arm DNA complexes.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(11):3913-20.
2005: Warren David; Lee Sang Yeol; Landy Arthur
Mutations in the amino-terminal domain of lambda-integrase have differential effects on integrative and excisive recombination.
Molecular microbiology 2005;55(4):1104-12.
2005: Lee Sang Yeol; Radman-Livaja Marta; Warren David; Aihara Hideki; Ellenberger Tom; Landy Arthur
Non-equivalent interactions between amino-terminal domains of neighboring lambda integrase protomers direct Holliday junction resolution.
Journal of molecular biology 2005;345(3):475-85.
2004: Lee Sang Yeol; Landy Arthur
The efficiency of mispaired ligations by lambda integrase is extremely sensitive to context.
Journal of molecular biology 2004;342(5):1647-58.
2004: Lee Sang Yeol; Aihara Hideki; Ellenberger Tom; Landy Arthur
Two structural features of lambda integrase that are critical for DNA cleavage by multimers but not by monomers.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(9):2770-5.
2003: Aihara Hideki; Kwon Hyock Joo; Nunes-Düby Simone E; Landy Arthur; Ellenberger Tom
A conformational switch controls the DNA cleavage activity of lambda integrase.
Molecular cell 2003;12(1):187-98.
2003: Warren David; Sam My D; Manley Kate; Sarkar Dibyendu; Lee Sang Yeol; Abbani Mohamad; Wojciak Jonathan M; Clubb Robert T; Landy Arthur
Identification of the lambda integrase surface that interacts with Xis reveals a residue that is also critical for Int dimer formation.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(14):8176-81.
2003: Radman-Livaja Marta; Shaw Christine; Azaro Marco; Biswas Tapan; Ellenberger Tom; Landy Arthur
Arm sequences contribute to the architecture and catalytic function of a lambda integrase-Holliday junction complex.
Molecular cell 2003;11(3):783-94.
2002: Sarkar Dibyendu; Azaro Marco A; Aihara Hideki; Papagiannis Christie V; Tirumalai Radhakrishna; Nunes-Düby Simone E; Johnson Reid C; Ellenberger Tom; Landy Arthur
Differential affinity and cooperativity functions of the amino-terminal 70 residues of lambda integrase.
Journal of molecular biology 2002;324(4):775-89.
2002: Tekle Michael; Warren David J; Biswas Tapan; Ellenberger Tom; Landy Arthur; Nunes-Düby Simone E
Attenuating functions of the C terminus of lambda integrase.
Journal of molecular biology 2002;324(4):649-65.
2002: Kovach Margaret J; Tirumalai Radhakrishna; Landy Arthur
Site-specific photo-cross-linking between lambda integrase and its DNA recombination target.
The Journal of biological chemistry 2002;277(17):14530-8.
2002: Wojciak Jonathan M; Sarkar Dibyendu; Landy Arthur; Clubb Robert T
Arm-site binding by lambda -integrase: solution structure and functional characterization of its amino-terminal domain.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):3434-9.
2002: Nunes-Düby Simone E; Radman-Livaja Marta; Kuimelis Robert G; Pearline Rachel V; McLaughlin Larry W; Landy Arthur
Gamma integrase complementation at the level of DNA binding and complex formation.
Journal of bacteriology 2002;184(5):1385-94.
2001: Sarkar D; Radman-Livaja M; Landy A
The small DNA binding domain of lambda integrase is a context-sensitive modulator of recombinase functions.
The EMBO journal 2001;20(5):1203-12.
1999: Landy A
Coming or going it's another pretty picture for the lambda-Int family album.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(13):7122-4.
1998: Tirumalai R S; Kwon H J; Cardente E H; Ellenberger T; Landy A
Recognition of core-type DNA sites by lambda integrase.
Journal of molecular biology 1998;279(3):513-27.
1998: Nunes-Düby S E; Kwon H J; Tirumalai R S; Ellenberger T; Landy A
Similarities and differences among 105 members of the Int family of site-specific recombinases.
Nucleic acids research 1998;26(2):391-406.
1997: Nunes-Düby S E; Yu D; Landy A
Sensing homology at the strand-swapping step in lambda excisive recombination.
Journal of molecular biology 1997;272(4):493-508.
1997: Azaro M A; Landy A
The isomeric preference of Holliday junctions influences resolution bias by lambda integrase.
The EMBO journal 1997;16(12):3744-55.
1997: Tirumalai R S; Healey E; Landy A
The catalytic domain of lambda site-specific recombinase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(12):6104-9.
1997: Kwon H J; Tirumalai R; Landy A; Ellenberger T
Flexibility in DNA recombination: structure of the lambda integrase catalytic core.
Science (New York, N.Y.) 1997;276(5309):126-31.
1997: Ellenberger T; Landy A
A good turn for DNA: the structure of integration host factor bound to DNA.
Structure (London, England : 1993) 1997;5(2):153-7.
1996: Tirumalai R S; Pargellis C A; Landy A
Identification and characterization of the N-ethylmaleimide-sensitive site in lambda-integrase.
The Journal of biological chemistry 1996;271(47):29599-604.
1995: Nunes-Düby S E; Smith-Mungo L I; Landy A
Single base-pair precision and structural rigidity in a small IHF-induced DNA loop.
Journal of molecular biology 1995;253(2):228-42.
1995: Nunes-Düby S E; Azaro M A; Landy A
Swapping DNA strands and sensing homology without branch migration in lambda site-specific recombination.
Current biology : CB 1995;5(2):139-48.
1995: Franz B; Landy A
The Holliday junction intermediates of lambda integrative and excisive recombination respond differently to the bending proteins integration host factor and excisionase.
The EMBO journal 1995;14(2):397-406.
1994: Nunes-Düby S E; Tirumalai R S; Dorgai L; Yagil E; Weisberg R A; Landy A
Lambda integrase cleaves DNA in cis.
The EMBO journal 1994;13(18):4421-30.
1994: Smith-Mungo L; Chan I T; Landy A
Structure of the P22 att site. Conservation and divergence in the lambda motif of recombinogenic complexes.
The Journal of biological chemistry 1994;269(32):20798-805.
1994: Kho S H; Landy A
Dissecting the resolution reaction of lambda integrase using suicide Holliday junction substrates.
The EMBO journal 1994;13(11):2714-24.
1993: Landy A
Mechanistic and structural complexity in the site-specific recombination pathways of Int and FLP.
Current opinion in genetics & development 1993;3(5):699-707.
1992: Kim S; Landy A
Lambda Int protein bridges between higher order complexes at two distant chromosomal loci attL and attR.
Science (New York, N.Y.) 1992;256(5054):198-203.
1991: Moitoso de Vargas L; Landy A
A switch in the formation of alternative DNA loops modulates lambda site-specific recombination.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(2):588-92.
1990: Kim S; Moitoso de Vargas L; Nunes-Düby S E; Landy A
Mapping of a higher order protein-DNA complex: two kinds of long-range interactions in lambda attL.
Cell 1990;63(4):773-81.
1990: Franz B; Landy A
Interactions between lambda Int molecules bound to sites in the region of strand exchange are required for efficient Holliday junction resolution.
Journal of molecular biology 1990;215(4):523-35.
1989: Nunes-Düby S E; Matsumoto L; Landy A
Half-att site substrates reveal the homology independence and minimal protein requirements for productive synapsis in lambda excisive recombination.
Cell 1989;59(1):197-206.
1989: Snyder U K; Thompson J F; Landy A
Phasing of protein-induced DNA bends in a recombination complex.
Nature 1989;341(6239):255-7.
1989: Moitoso de Vargas L; Kim S; Landy A
DNA looping generated by DNA bending protein IHF and the two domains of lambda integrase.
Science (New York, N.Y.) 1989;244(4911):1457-61.
1989: Landy A
Dynamic, structural, and regulatory aspects of lambda site-specific recombination.
Annual review of biochemistry 1989;58():913-49.
1989: Madden K A; Landy A
Rho-dependent transcription termination in the tyrT operon of Escherichia coli.
Gene 1989;76(2):271-80.
1988: Thompson J F; Landy A
Empirical estimation of protein-induced DNA bending angles: applications to lambda site-specific recombination complexes.
Nucleic acids research 1988;16(20):9687-705.
1988: Moitoso de Vargas L; Pargellis C A; Hasan N M; Bushman E W; Landy A
Autonomous DNA binding domains of lambda integrase recognize two different sequence families.
Cell 1988;54(7):923-9.
1988: Thompson J F; Snyder U K; Landy A
Helical-repeat dependence of integrative recombination of bacteriophage lambda: role of the P1 and H1 protein binding sites.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(17):6323-7.
1988: Pargellis C A; Nunes-Düby S E; de Vargas L M; Landy A
Suicide recombination substrates yield covalent lambda integrase-DNA complexes and lead to identification of the active site tyrosine.
The Journal of biological chemistry 1988;263(16):7678-85.
1987: Thompson J F; Moitoso de Vargas L; Koch C; Kahmann R; Landy A
Cellular factors couple recombination with growth phase: characterization of a new component in the lambda site-specific recombination pathway.
Cell 1987;50(6):901-8.
1987: Nunes-Düby S E; Matsumoto L; Landy A
Site-specific recombination intermediates trapped with suicide substrates.
Cell 1987;50(5):779-88.
1987: Thompson J F; de Vargas L M; Skinner S E; Landy A
Protein-protein interactions in a higher-order structure direct lambda site-specific recombination.
Journal of molecular biology 1987;195(3):481-93.
1986: Thompson J F; Waechter-Brulla D; Gumport R I; Gardner J F; Moitoso de Vargas L; Landy A
Mutations in an integration host factor-binding site: effect on lambda site-specific recombination and regulatory implications.
Journal of bacteriology 1986;168(3):1343-51.
1986: Leong J M; Nunes-Düby S E; Oser A B; Lesser C F; Youderian P; Susskind M M; Landy A
Structural and regulatory divergence among site-specific recombination genes of lambdoid phage.
Journal of molecular biology 1986;189(4):603-16.
1986: Argos P; Landy A; Abremski K; Egan J B; Haggard-Ljungquist E; Hoess R H; Kahn M L; Kalionis B; Narayana S V; Pierson L S
The integrase family of site-specific recombinases: regional similarities and global diversity.
The EMBO journal 1986;5(2):433-40.
1985: Leong J M; Nunes-Düby S E; Landy A
Generation of single base-pair deletions, insertions, and substitutions by a site-specific recombination system.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(20):6990-4.
1985: Leong J M; Nunes-Düby S; Lesser C F; Youderian P; Susskind M M; Landy A
The phi 80 and P22 attachment sites. Primary structure and interaction with Escherichia coli integration host factor.
The Journal of biological chemistry 1985;260(7):4468-77.
1984: Hsu P L; Landy A
Resolution of synthetic att-site Holliday structures by the integrase protein of bacteriophage lambda.
Nature 1984;311(5988):721-6.
1984: Leong J M; Nunes-Duby S; Oser A; Lesser C F; Youderian P; Susskind M M; Landy A
Site-specific recombination systems of phages phi 80 and P22: binding sites of integration host factor and recombination-induced mutations.
Cold Spring Harbor symposia on quantitative biology 1984;49():707-14.
1983: Weisberg R A; Enquist L W; Foeller C; Landy A
Role for DNA homology in site-specific recombination. The isolation and characterization of a site affinity mutant of coliphage lambda.
Journal of molecular biology 1983;170(2):319-42.
1981: Mizuuchi K; Weisberg R; Enquist L; Mizuuchi M; Buraczynska M; Foeller C; Hsu P L; Ross W; Landy A
Structure and function of the phage lambda att site: size, int-binding sites, and location of the crossover point.
Cold Spring Harbor symposia on quantitative biology 1981;45 Pt 1():429-37.
1980: Landy A; Hsu P L; Ross W; Buraczynska M
Site-specific recombination in bacteriophage lambda: structural analyses of reactive DNA sequences.
The American journal of tropical medicine and hygiene 1980;29(5 Suppl):1099-106.
1980: Hoess R H; Foeller C; Bidwell K; Landy A
Site-specific recombination functions of bacteriophage lambda: DNA sequence of regulatory regions and overlapping structural genes for Int and Xis.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(5):2482-6.
1980: Hsu P L; Ross W; Landy A
The lambda phage att site: functional limits and interaction with Int protein.
Nature 1980;285(5760):85-91.

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