FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Thomas Lane

Research Profile

Living Beings

Disorders

Chemicals & Drugs

Anatomy

Physiology

Co-author Network

Publications

TOP 3
Emanuele Tirotta; Michelle R Tsukamoto; Jean Oak; Patrick Duncker; Lanny Gov; Suzi Klaus; Thomas E Lane
Epstein-Barr virus-induced gene 3 negatively regulates neuroinflammation and T cell activation following coronavirus-induced encephalomyelitis.
Jason G Weinger; Brett S Marro; Martin P Hosking; Thomas E Lane
The chemokine receptor CXCR2 and coronavirus-induced neurologic disease.
Jason G Weinger; Brian M Weist; Suzi M Klaus; Warren C Plaisted; Craig M Walsh; Thomas E Lane
MHC mismatch results in neural progenitor cell rejection following spinal cord transplantation in a model of viral-induced demyelination.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Thomas Lane (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Emanuele Tirotta; Michelle R Tsukamoto; Jean Oak; Patrick Duncker; Lanny Gov; Suzi Klaus; Thomas E Lane
Epstein-Barr virus-induced gene 3 negatively regulates neuroinflammation and T cell activation following coronavirus-induced encephalomyelitis.
Journal of neuroimmunology 2013;254(1-2):110-6.
2013: Jason G Weinger; Brett S Marro; Martin P Hosking; Thomas E Lane
The chemokine receptor CXCR2 and coronavirus-induced neurologic disease.
Virology 2013;435(1):110-7.
2012: Jason G Weinger; Brian M Weist; Suzi M Klaus; Warren C Plaisted; Craig M Walsh; Thomas E Lane
MHC mismatch results in neural progenitor cell rejection following spinal cord transplantation in a model of viral-induced demyelination.
Stem cells (Dayton, Ohio) 2012;30(11):2584-95.
2012: Emanuele Tirotta; Maya N Hatch; Leslie A Kirby; Thomas E Lane
IFN-γ-induced apoptosis of human embryonic stem cell derived oligodendrocyte progenitor cells is restricted by CXCR2 signaling.
Stem cell research 2012;9(3):208-17.
2012: Lucia M Whitman; Caroline A Blanc; David H Rowitch; Chris S Schaumburg; Thomas E Lane
Olig1 function is required for remyelination potential of transplanted neural progenitor cells in a model of viral-induced demyelination.
Experimental neurology 2012;235(1):380-7.
2012: Janet Z Liu; Paolo Pasquali; Michele Pesciaroli; Adam J Poe; Andrea Battistoni; Walter J Chazin; Robert A Edwards; Martin P Hosking; Stefan Jellbauer; Thomas E Kehl-Fie; Thomas E Lane; Nicole A Restrepo; Johannes Roth; Eric P Skaar; Vivian Ton; Thomas Vogl; Manuela Raffatellu
Zinc sequestration by the neutrophil protein calprotectin enhances Salmonella growth in the inflamed gut.
Cell host & microbe 2012;11(3):227-39.
2011: Kevin S Carbajal; Juan L Miranda; Michelle R Tsukamoto; Thomas E Lane
CXCR4 signaling regulates remyelination by endogenous oligodendrocyte progenitor cells in a viral model of demyelination.
Glia 2011;59(12):1813-21.
2011: Emanuele Tirotta; Richard M Ransohoff; Thomas E Lane
CXCR2 signaling protects oligodendrocyte progenitor cells from IFN-γ/CXCL10-mediated apoptosis.
Glia 2011;59(10):1518-28.
2011: Jennifer V Lu; Keith A Luhrs; Brett S Marro; Long V Nguyen; Guy S Salvesen; Prathna Srinivas; Bram J van Raam; Bryan D Bell; Thomas E Lane; Brian M Weist; Craig M Walsh
Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(37):15312-7.
2011: Michael Sy; Masashi Kitazawa; Rodrigo Medeiros; Lucia Whitman; David Cheng; Thomas E Lane; Frank M LaFerla
Inflammation induced by infection potentiates tau pathological features in transgenic mice.
The American journal of pathology 2011;178(6):2811-22.
2011: Kevin S Carbajal; Chris S Schaumburg; Jason G Weinger; Lucia M Whitman; Thomas E Lane
Surgical transplantation of mouse neural stem cells into the spinal cords of mice infected with neurotropic mouse hepatitis virus.
Journal of visualized experiments : JoVE 2011;(53):e2834.
2010: Katherine S Held; Oswald Steward; Caroline Blanc; Thomas E Lane
Impaired immune responses following spinal cord injury lead to reduced ability to control viral infection.
Experimental neurology 2010;226(1):242-53.
2010: Emanuele Tirotta; Kevin S Carbajal; Chris S Schaumburg; Lucia Whitman; Thomas E Lane
Cell replacement therapies to promote remyelination in a viral model of demyelination.
Journal of neuroimmunology 2010;224(1-2):101-7.
2010: LiPing Liu; Lindsey Darnall; Taofang Hu; Karen Choi; Thomas E Lane; Richard M Ransohoff
Myelin repair is accelerated by inactivating CXCR2 on nonhematopoietic cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(27):9074-83.
2010: Kevin S Carbajal; Chris S Schaumburg; Robert Strieter; Joy Kane; Thomas E Lane
Migration of engrafted neural stem cells is mediated by CXCL12 signaling through CXCR4 in a viral model of multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(24):11068-73.
2010: Liping Liu; Abdelmadjid Belkadi; Lindsey Darnall; Taofang Hu; Caitlin Drescher; Anne C Cotleur; Dolly Padovani-Claudio; Tao He; Karen Choi; Thomas E Lane; Robert H Miller; Richard M Ransohoff
CXCR2-positive neutrophils are essential for cuprizone-induced demyelination: relevance to multiple sclerosis.
Nature neuroscience 2010;13(3):319-26.
2010: Martin P Hosking; Thomas E Lane
The role of chemokines during viral infection of the CNS.
PLoS pathogens 2010;6(7):e1000937.
2010: Martin P Hosking; Emanuele Tirotta; Richard M Ransohoff; Thomas E Lane
CXCR2 signaling protects oligodendrocytes and restricts demyelination in a mouse model of viral-induced demyelination.
PloS one 2010;5(6):e11340.
2010: Thomas E Lane; Martin P Hosking
The pathogenesis of murine coronavirus infection of the central nervous system.
Critical reviews in immunology 2010;30(2):119-30.
2009: Martin P Hosking; Liping Liu; Richard M Ransohoff; Thomas E Lane
A protective role for ELR+ chemokines during acute viral encephalomyelitis.
PLoS pathogens 2009;5(11):e1000648.
2009: Linda N Stiles; Michael T Liu; Joy A C Kane; Thomas E Lane
CXCL10 and trafficking of virus-specific T cells during coronavirus-induced demyelination.
Autoimmunity 2009;42(6):484-91.
2009: Maya N Hatch; Chris S Schaumburg; Thomas E Lane; Hans S Keirstead
Endogenous remyelination is induced by transplant rejection in a viral model of multiple sclerosis.
Journal of neuroimmunology 2009;212(1-2):74-81.
2009: Lucia Whitman; Haixia Zhou; Stanley Perlman; Thomas E Lane
IFN-gamma-mediated suppression of coronavirus replication in glial-committed progenitor cells.
Virology 2009;384(1):209-15.
2008: Michael Muse; Joy A C Kane; Daniel J J Carr; Joshua M Farber; Thomas E Lane
Insertion of the CXC chemokine ligand 9 (CXCL9) into the mouse hepatitis virus genome results in protection from viral-induced encephalitis and hepatitis.
Virology 2008;382(2):132-44.
2008: Chris S Schaumburg; B A O'Hara; Thomas E Lane; W J Atwood
Human embryonic stem cell-derived oligodendrocyte progenitor cells express the serotonin receptor and are susceptible to JC virus infection.
Journal of virology 2008;82(17):8896-9.
2008: Katherine S Held; William G Glass; Yevgeniya I Orlovsky; Kimberly A Shamberger; Ted D Petley; Patrick J Branigan; Jill M Carton; Heena S Beck; Mark R Cunningham; Jacqueline M Benson; Thomas E Lane
Generation of a protective T-cell response following coronavirus infection of the central nervous system is not dependent on IL-12/23 signaling.
Viral immunology 2008;21(2):173-88.
2008: Kevin B Walsh; Lewis L Lanier; Thomas E Lane
NKG2D receptor signaling enhances cytolytic activity by virus-specific CD8+ T cells: evidence for a protective role in virus-induced encephalitis.
Journal of virology 2008;82(6):3031-44.
2008: Kevin B Walsh; Melissa B Lodoen; Robert Edwards; Lewis L Lanier; Thomas E Lane
Evidence for differential roles for NKG2D receptor signaling in innate host defense against coronavirus-induced neurological and liver disease.
Journal of virology 2008;82(6):3021-30.
2008: Chris S Schaumburg; Katherine S Held; Thomas E Lane
Mouse hepatitis virus infection of the CNS: a model for defense, disease, and repair.
Frontiers in bioscience : a journal and virtual library 2008;13():4393-406.
2007: Michelle J Hickey; Katherine S Held; Elizabeth Baum; Ji-Liang Gao; Philip M Murphy; Thomas E Lane
CCR1 deficiency increases susceptibility to fatal coronavirus infection of the central nervous system.
Viral immunology 2007;20(4):599-608.
2007: Chris S Schaumburg; Martina Gatzka; Craig M Walsh; Thomas E Lane
DRAK2 regulates memory T cell responses following murine coronavirus infection.
Autoimmunity 2007;40(7):483-8.
2007: Rafael Gonzalez; Michelle J Hickey; Julio M Espinosa; Gabriel Nistor; Thomas E Lane; Hans S Keirstead
Therapeutic neutralization of CXCL10 decreases secondary degeneration and functional deficit after spinal cord injury in mice.
Regenerative medicine 2007;2(5):771-83.
2007: Kevin B Walsh; Robert Edwards; Kimberley M Romero; Matthew V Kotlajich; Stephen A Stohlman; Thomas E Lane
Expression of CXC chemokine ligand 10 from the mouse hepatitis virus genome results in protection from viral-induced neurological and liver disease.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(2):1155-65.
2007: Jonathan Deane; Michael G Kharas; Jean S Oak; Linda N Stiles; Ji Luo; Travis I Moore; Hong Ji; Christian Rommel; Lewis C Cantley; Thomas E Lane; David A Fruman
T-cell function is partially maintained in the absence of class IA phosphoinositide 3-kinase signaling.
Blood 2007;109(7):2894-902.
2007: Stephanie J Ramos; Jenny L Hardison; Linda N Stiles; Thomas E Lane; Craig M Walsh
Anti-viral effector T cell responses and trafficking are not dependent upon DRAK2 signaling following viral infection of the central nervous system.
Autoimmunity 2007;40(1):54-65.
2006: Linda N Stiles; Jenny L Hardison; Chris S Schaumburg; Lucia M Whitman; Thomas E Lane
T cell antiviral effector function is not dependent on CXCL10 following murine coronavirus infection.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(12):8372-80.
2006: Jean S Oak; Jonathan Deane; Michael G Kharas; Ji Luo; Thomas E Lane; Lewis C Cantley; David A Fruman
Sjögren's syndrome-like disease in mice with T cells lacking class 1A phosphoinositide-3-kinase.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(45):16882-7.
2006: Jenny L Hardison; William Kuziel; Jerry E Manning; Thomas E Lane
Chemokine CC receptor 2 is important for acute control of cardiac parasitism but does not contribute to cardiac inflammation after infection with Trypanosoma cruzi.
The Journal of infectious diseases 2006;193(11):1584-8.
2006: Linda N Stiles; Martin P Hosking; Robert Edwards; Robert M Strieter; Thomas E Lane
Differential roles for CXCR3 in CD4+ and CD8+ T cell trafficking following viral infection of the CNS.
European journal of immunology 2006;36(3):613-22.
2006: Cornelia C Bergmann; Thomas E Lane; Stephen A Stohlman
Coronavirus infection of the central nervous system: host-virus stand-off.
Nature reviews. Microbiology 2006;4(2):121-32.
2006: Jenny L Hardison; Gabriel Nistor; Rafael Gonzalez; Hans S Keirstead; Thomas E Lane
Transplantation of glial-committed progenitor cells into a viral model of multiple sclerosis induces remyelination in the absence of an attenuated inflammatory response.
Experimental neurology 2006;197(2):420-9.
2006: Kevin B Walsh; Melissa B Lodoen; Lewis L Lanier; Thomas E Lane
NKG2D signaling and host defense after mouse hepatitis virus infection of the central nervous system.
Advances in experimental medicine and biology 2006;581():369-72.
2006: Thomas E Lane; Jenny L Hardison; Kevin B Walsh
Functional diversity of chemokines and chemokine receptors in response to viral infection of the central nervous system.
Current topics in microbiology and immunology 2006;303():1-27.
2006: Jenny L Hardison; Ruth A Wrightsman; Philip M Carpenter; William Kuziel; Thomas E Lane; Jerry E Manning
The CC chemokine receptor 5 is important in control of parasite replication and acute cardiac inflammation following infection with Trypanosoma cruzi.
Infection and immunity 2006;74(1):135-43.
2006: Jenny L Hardison; Ruth A Wrightsman; Philip M Carpenter; Thomas E Lane; Jerry E Manning
The chemokines CXCL9 and CXCL10 promote a protective immune response but do not contribute to cardiac inflammation following infection with Trypanosoma cruzi.
Infection and immunity 2006;74(1):125-34.
2004: Katherine S Held; Benjamin P Chen; William Kuziel; Barrett J Rollins; Thomas E Lane
Differential roles of CCL2 and CCR2 in host defense to coronavirus infection.
Virology 2004;329(2):251-60.
2004: Matthew J Trifilo; Thomas E Lane
The CC chemokine ligand 3 regulates CD11c+CD11b+CD8alpha- dendritic cell maturation and activation following viral infection of the central nervous system: implications for a role in T cell activation.
Virology 2004;327(1):8-15.
2004: Jonathan Deane; Matthew J Trifilo; Claudine M Yballe; Sangdun Choi; Thomas E Lane; David A Fruman
Enhanced T cell proliferation in mice lacking the p85beta subunit of phosphoinositide 3-kinase.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(11):6615-25.
2004: Minodora O Totoiu; Gabriel Nistor; Thomas E Lane; Hans S Keirstead
Remyelination, axonal sparing, and locomotor recovery following transplantation of glial-committed progenitor cells into the MHV model of multiple sclerosis.
Experimental neurology 2004;187(2):254-65.
2004: William G Glass; Michelle J Hickey; Jenny L Hardison; Michael T Liu; Jerry E Manning; Thomas E Lane
Antibody targeting of the CC chemokine ligand 5 results in diminished leukocyte infiltration into the central nervous system and reduced neurologic disease in a viral model of multiple sclerosis.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(7):4018-25.
2004: Matthew J Trifilo; Cynthia Montalto-Morrison; Linda N Stiles; Kelley R Hurst; Jenny L Hardison; Jerry E Manning; Paul S Masters; Thomas E Lane
CXC chemokine ligand 10 controls viral infection in the central nervous system: evidence for a role in innate immune response through recruitment and activation of natural killer cells.
Journal of virology 2004;78(2):585-94.
2003: Rafael Gonzalez; Janette Glaser; Michael T Liu; Thomas E Lane; Hans S Keirstead
Reducing inflammation decreases secondary degeneration and functional deficit after spinal cord injury.
Experimental neurology 2003;184(1):456-63.
2003: William G Glass; Thomas E Lane
Functional analysis of the CC chemokine receptor 5 (CCR5) on virus-specific CD8+ T cells following coronavirus infection of the central nervous system.
Virology 2003;312(2):407-14.
2003: Matthew J Trifilo; Thomas E Lane
Adenovirus-mediated expression of CXCL10 in the central nervous system results in T-cell recruitment and limited neuropathology.
Journal of neurovirology 2003;9(3):315-24.
2003: Matthew J Trifilo; Cornelia C Bergmann; William Kuziel; Thomas E Lane
CC chemokine ligand 3 (CCL3) regulates CD8(+)-T-cell effector function and migration following viral infection.
Journal of virology 2003;77(7):4004-14.
2003: William G Glass; Thomas E Lane
Functional expression of chemokine receptor CCR5 on CD4(+) T cells during virus-induced central nervous system disease.
Journal of virology 2003;77(1):191-8.
2002: Benjamin P Chen; Thomas E Lane
Lack of nitric oxide synthase type 2 (NOS2) results in reduced neuronal apoptosis and mortality following mouse hepatitis virus infection of the central nervous system.
Journal of neurovirology 2002;8(1):58-63.
2002: William G Glass; Benjamin P Chen; Michael T Liu; Thomas E Lane
Mouse hepatitis virus infection of the central nervous system: chemokine-mediated regulation of host defense and disease.
Viral immunology 2002;15(2):261-72.
2001: Kazuhiro Kakimi; Thomas E Lane; Stefan F Wieland; Valérie C Asensio; Iain L Campbell; Francis V Chisari; Luca G Guidotti
Blocking chemokine responsive to gamma-2/interferon (IFN)-gamma inducible protein and monokine induced by IFN-gamma activity in vivo reduces the pathogenetic but not the antiviral potential of hepatitis B virus-specific cytotoxic T lymphocytes.
The Journal of experimental medicine 2001;194(12):1755-66.
2001: Kazuhiro Kakimi; Thomas E Lane; Francis V Chisari; Luca G Guidotti
Cutting edge: Inhibition of hepatitis B virus replication by activated NK T cells does not require inflammatory cell recruitment to the liver.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(12):6701-5.
2001: Benjamin P Chen; William Kuziel; Thomas E Lane
Lack of CCR2 results in increased mortality and impaired leukocyte activation and trafficking following infection of the central nervous system with a neurotropic coronavirus.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(8):4585-92.
2001: M T Liu; Hans S Keirstead; Thomas E Lane
Neutralization of the chemokine CXCL10 reduces inflammatory cell invasion and demyelination and improves neurological function in a viral model of multiple sclerosis.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(7):4091-7.
2001: William G Glass; Michael T Liu; William Kuziel; Thomas E Lane
Reduced macrophage infiltration and demyelination in mice lacking the chemokine receptor CCR5 following infection with a neurotropic coronavirus.
Virology 2001;288(1):8-17.
2001: Michael T Liu; D Armstrong; Thomas Hamilton; Thomas E Lane
Expression of Mig (monokine induced by interferon-gamma) is important in T lymphocyte recruitment and host defense following viral infection of the central nervous system.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(3):1790-5.
2001: Michael T Liu; Benjamin P Chen; P Oertel; Michael J Buchmeier; Thomas Hamilton; David A Armstrong; Thomas E Lane
The CXC chemokines IP-10 and Mig are essential in host defense following infection with a neurotropic coronavirus.
Advances in experimental medicine and biology 2001;494():323-7.
2001: Michael T Liu; Thomas E Lane
Chemokine expression and viral infection of the central nervous system: regulation of host defense and neuropathology.
Immunologic research 2001;24(2):111-9.
2000: Michael T Liu; Benjamin P Chen; P Oertel; Michael J Buchmeier; D Armstrong; Thomas Hamilton; Thomas E Lane
The T cell chemoattractant IFN-inducible protein 10 is essential in host defense against viral-induced neurologic disease.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(5):2327-30.
2000: Thomas E Lane; Michael T Liu; Benjamin P Chen; Valérie C Asensio; R M Samawi; AD Paoletti; Iain L Campbell; Steven Kunkel; Howard S Fox; Michael J Buchmeier
A central role for CD4(+) T cells and RANTES in virus-induced central nervous system inflammation and demyelination.
Journal of virology 2000;74(3):1415-24.
1999: Jyrki Törnwall; Thomas E Lane; Robert I Fox; Howard S Fox
T cell attractant chemokine expression initiates lacrimal gland destruction in nonobese diabetic mice.
Laboratory investigation; a journal of technical methods and pathology 1999;79(12):1719-26.
1999: Michael J Buchmeier; Thomas E Lane
Viral-induced neurodegenerative disease.
Current opinion in microbiology 1999;2(4):398-402.
1999: M Koo; Mohammed Bendahmane; G A Lettieri; A D Paoletti; Thomas E Lane; J H Fitchen; Michael J Buchmeier; Roger N Beachy
Protective immunity against murine hepatitis virus (MHV) induced by intranasal or subcutaneous administration of hybrids of tobacco mosaic virus that carries an MHV epitope.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(14):7774-9.
1999: Thomas E Lane; Howard S Fox; Michael J Buchmeier
Inhibition of nitric oxide synthase-2 reduces the severity of mouse hepatitis virus-induced demyelination: implications for NOS2/NO regulation of chemokine expression and inflammation.
Journal of neurovirology 1999;5(1):48-54.
1998: Thomas E Lane; Valérie C Asensio; N Yu; AD Paoletti; Iain L Campbell; Michael J Buchmeier
Dynamic regulation of alpha- and beta-chemokine expression in the central nervous system during mouse hepatitis virus-induced demyelinating disease.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(2):970-8.
1997: Thomas E Lane; AD Paoletti; Michael J Buchmeier
Disassociation between the in vitro and in vivo effects of nitric oxide on a neurotropic murine coronavirus.
Journal of virology 1997;71(3):2202-10.
1997: Thomas E Lane; Michael J Buchmeier
Murine coronavirus infection: a paradigm for virus-induced demyelinating disease.
Trends in microbiology 1997;5(1):9-14.
1996: Thomas E Lane; Michael J Buchmeier; D D Watry; Howard S Fox
Expression of inflammatory cytokines and inducible nitric oxide synthase in brains of SIV-infected rhesus monkeys: applications to HIV-induced central nervous system disease.
Molecular medicine (Cambridge, Mass.) 1996;2(1):27-37.
1995: Thomas E Lane; Michael J Buchmeier; D D Watry; D B Jakubowski; Howard S Fox
Serial passage of microglial SIV results in selection of homogeneous env quasispecies in the brain.
Virology 1995;212(2):458-65.
1995: D Watry; Thomas E Lane; M Streb; Howard S Fox
Transfer of neuropathogenic simian immunodeficiency virus with naturally infected microglia.
The American journal of pathology 1995;146(4):914-23.