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Robert Langer

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Tram T Dang; Joshua C Doloff; Zhen Gu; Jennifer Hollister-Lock; Robert Langer; Minglin Ma; Karolina Siniakowicz; Jeremy E Slosberg; Katherine M Tang; Anh V Thai; Gordon C Weir; Hao Cheng; Joshua Cohen; Daniel G Anderson
Enhanced function of immuno-isolated islets in diabetes therapy by co-encapsulation with an anti-inflammatory drug.
Andrew L Hook; Robert Langer; Paul Williams; Jing Yang; Daniel G Anderson; Steve Atkinson; Chien-Yi Chang; Martyn C Davies; Morgan R Alexander
Discovery of novel materials with broad resistance to bacterial attachment using combinatorial polymer microarrays.
Pedro M Valencia; Neil H Bander; Suresh Gadde; Philip W Kantoff; Rohit Karnik; Robert Langer; Stephen J Lippard; Brian Perea; Eric M Pridgen; Christopher Sweeney; Omid C Farokhzad
Synergistic cytotoxicity of irinotecan and cisplatin in dual-drug targeted polymeric nanoparticles.

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2013: Tram T Dang; Joshua C Doloff; Zhen Gu; Jennifer Hollister-Lock; Robert Langer; Minglin Ma; Karolina Siniakowicz; Jeremy E Slosberg; Katherine M Tang; Anh V Thai; Gordon C Weir; Hao Cheng; Joshua Cohen; Daniel G Anderson
Enhanced function of immuno-isolated islets in diabetes therapy by co-encapsulation with an anti-inflammatory drug.
Biomaterials 2013;34(23):5792-801.
2013: Andrew L Hook; Robert Langer; Paul Williams; Jing Yang; Daniel G Anderson; Steve Atkinson; Chien-Yi Chang; Martyn C Davies; Morgan R Alexander
Discovery of novel materials with broad resistance to bacterial attachment using combinatorial polymer microarrays.
Advanced materials (Deerfield Beach, Fla.) 2013;25(18):2542-7.
2013: Pedro M Valencia; Neil H Bander; Suresh Gadde; Philip W Kantoff; Rohit Karnik; Robert Langer; Stephen J Lippard; Brian Perea; Eric M Pridgen; Christopher Sweeney; Omid C Farokhzad
Synergistic cytotoxicity of irinotecan and cisplatin in dual-drug targeted polymeric nanoparticles.
Nanomedicine (London, England) 2013;8(5):687-98.
2013: Nazila Kamaly; Robert Langer; Aleksandar Pesic; Manikandan Subramanian; Ira Tabas; Louis Cheung; Zahi Adel Fayad; Gabrielle Fredman; Suresh Gadde; Omid Cameron Farokhzad
Development and in vivo efficacy of targeted polymeric inflammation-resolving nanoparticles.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(16):6506-11.
2013: Daniel K Bonner; Hilda Buss; Robert Langer; Xiaoyong Zhao; Paula T Hammond
Crosslinked linear polyethylenimine enhances delivery of DNA to the cytoplasm.
Journal of controlled release : official journal of the Controlled Release Society 2013;167(1):101-7.
2013: Shan Jiang; Robert Langer; Kevin T Love; Ahmed A Eltoukhy; Daniel G Anderson
Lipidoid-coated iron oxide nanoparticles for efficient DNA and siRNA delivery.
Nano letters 2013;13(3):1059-64.
2013: Ahmed A Eltoukhy; Robert Langer; Christopher A Alabi; Delai Chen; Daniel G Anderson
Degradable terpolymers with alkyl side chains demonstrate enhanced gene delivery potency and nanoparticle stability.
Advanced materials (Deerfield Beach, Fla.) 2013;25(10):1487-93.
2013: Daniel A Heller; Shan Jiang; Daniel S Kohane; Robert Langer; Yair Levi; Miguel Manzano; Jeisa M Pelet; George W Pratt; William Querbes; Gaurav Sahay; Avi Schroeder; Josh E Schroeder; Jasmine Wallas; Christopher Zurenko; Yieu Chyan; Joshua C Doloff; Daniel G Anderson
Modular 'click-in-emulsion' bone-targeted nanogels.
Advanced materials (Deerfield Beach, Fla.) 2013;25(10):1449-54.
2013: Rizwan Haq; Elena B Hawryluk; Dave S B Hoon; Göran B Jönsson; Robert Langer; Kevin T Love; Kevin McHenry; Donald L Morton; Dale Porter; Jun S Song; Thanh-Nga Tran; Jennifer A Wargo; Satoru Yokoyama; Daniel G Anderson; Lyn McDivitt Duncan; Dennie Tompers Frederick; Levi A Garraway; David E Fisher
BCL2A1 is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(11):4321-6.
2013: Rebekah A Neal; Hyoungshin Park; Patrick B Wu; George C Engelmayr; James Hsiao; Aurélie Jean; Robert Langer; Lisa E Freed
Three-dimensional elastomeric scaffolds designed with cardiac-mimetic structural and mechanical features.
Tissue engineering. Part A 2013;19(5-6):793-807.
2013: Maria José Nunes Pereira; Irina Pomerantseva; Debanjan Sarkar; Cathryn A Sundback; Pedro Del Nido; Lino S Ferreira; Ingeborg Friehs; Nora Lang; Robert Langer; Peter T Masiakos; Jacob McFadden; Mark C Mochel; Shwetha Mureli; Olive Mwizerwa; Ben Ouyang; jeff karp
A highly tunable biocompatible and multifunctional biodegradable elastomer.
Advanced materials (Deerfield Beach, Fla.) 2013;25(8):1209-15.
2013: Armon Sharei; Woo Young Sim; Janet Zoldan; Andrea Adamo; Daniel G Anderson; Pamela A Basto; Nahyun Cho; Min-Joon Han; George C Hartoularos; Daniel A Heller; Emily Jackson; Siddharth Jhunjhunwala; Jeon Woong Kang; Kwang-Soo Kim; Robert Langer; Jungmin Lee; Abigail Lytton-Jean; Shirley Mao; Sabine Schneider; Klavs F Jensen
A vector-free microfluidic platform for intracellular delivery.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(6):2082-7.
2013: Michinao Hashimoto; Robert Langer; Daniel S Kohane
Benchtop fabrication of microfluidic systems based on curable polymers with improved solvent compatibility.
Lab on a chip 2013;13(2):252-9.
2013: Mingming Ma; Daniel G Anderson; Liang Guo; Robert Langer
Bio-inspired polymer composite actuator and generator driven by water gradients.
Science (New York, N.Y.) 2013;339(6116):186-9.
2013: Xiaojuan Khoo; Homer H Chiang; Julia M Hickey; Robert Langer; Stephen I Pelton; John J Rosowski; Vishakha Sabharwal; Emmanuel J Simons; Daniel S Kohane
Formulations for trans-tympanic antibiotic delivery.
Biomaterials 2013;34(4):1281-8.
2013: Christopher A Alabi; Robert Langer; Gaurav Sahay; Daniel G Anderson
Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles.
Integrative biology : quantitative biosciences from nano to macro 2013;5(1):224-30.
2012: Christian J Kastrup; Robert Langer; Haeshin Lee; Timothy Lee; Samantha MacDougall; Matthias Nahrendorf; Michael Okonkwo; Christopher D Pritchard; Cory D Siegel; James R Stone; Anh Thai; Arturo J Vegas; Ralph Weissleder; Ju Hun Yeon; Hao Cheng; Seung-Woo Cho; Arthur J Coury; Tram T Dang; Partha Dutta; Jose-Luiz Figueiredo; Rostic Gorbatov; Yoshiko Iwamoto; Swetha Kambhampati; Daniel G Anderson
Painting blood vessels and atherosclerotic plaques with an adhesive drug depot.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(52):21444-9.
2012: Jungmin Lee; Armon Sharei; Woo Young Sim; Andrea Adamo; Klavs F Jensen; Robert Langer; Moungi G Bawendi
Nonendocytic delivery of functional engineered nanoparticles into the cytoplasm of live cells using a novel, high-throughput microfluidic device.
Nano letters 2012;12(12):6322-7.
2012: Halil Tekin; Karen Dubbin; Christian Landeros; Robert Langer; Jefferson G Sanchez; Ali Khademhosseini
Controlling spatial organization of multiple cell types in defined 3D geometries.
Advanced materials (Deerfield Beach, Fla.) 2012;24(41):5543-7, 5542.
2012: Sahadev A Shankarappa; Jonathan H Tsui; Jenny C Dohlman; Kristine N Kim; Robert Langer; Gally Reznor; Daniel S Kohane
Prolonged nerve blockade delays the onset of neuropathic pain.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(43):17555-60.
2012: Tzahi Cohen-Karni; Adam Graham; Kyung Jae Jeong; Robert Langer; Carolyn Marks; Mirela Mustata; Gally Reznor; Jonathan H Tsui; Meni Wanunu; David C Bell; Daniel S Kohane
Nanocomposite gold-silk nanofibers.
Nano letters 2012;12(10):5403-6.
2012: Nathaniel M Vacanti; Shanée Watson; Hao Cheng; Tram T Dang; João D T Guerreiro; Paulina S Hill; Nathaniel S Hwang; Robert Langer; Minglin Ma; Daniel G Anderson
Localized delivery of dexamethasone from electrospun fibers reduces the foreign body response.
Biomacromolecules 2012;13(10):3031-8.
2012: Leon M Bellan; Donald M Cropek; Matthew Pearsall; Robert Langer
A 3D interconnected microchannel network formed in gelatin by sacrificial shellac microfibers.
Advanced materials (Deerfield Beach, Fla.) 2012;24(38):5187-91.
2012: Robert Langer
Leading the way in biomedical engineering: an interview with Robert Langer. Interview by Hannah Stanwix, Commissioning Editor.
Nanomedicine (London, England) 2012;7(10):1483-4.
2012: Pedro M Valencia; Omid C Farokhzad; Rohit Karnik; Robert Langer
Microfluidic technologies for accelerating the clinical translation of nanoparticles.
Nature nanotechnology 2012;7(10):623-9.
2012: Andrew L Hook; Derek J Irvine; Robert Langer; Jeni Luckett; Ying Mei; Paul Williams; Jing Yang; Daniel G Anderson; Steve Atkinson; Roger Bayston; Chien-Yi Chang; Alan Cockayne; Martyn C Davies; Morgan R Alexander
Combinatorial discovery of polymers resistant to bacterial attachment.
Nature biotechnology 2012;30(9):868-75.
2012: Tzahi Cohen-Karni; Robert Langer; Daniel S Kohane
The smartest materials: the future of nanoelectronics in medicine.
ACS nano 2012;6(8):6541-5.
2012: Byron C Masi; Betty M. Tyler; Robert T Wicks; Yuan Xue; Hansen Bow; Henry Brem; Robert Langer; Michael J Cima
Intracranial MEMS based temozolomide delivery in a 9L rat gliosarcoma model.
Biomaterials 2012;33(23):5768-75.
2012: Christopher A Alabi; Robert Langer; Kevin T Love; Gaurav Sahay; Tina Stutzman; Whitney T Young; Daniel G Anderson
FRET-labeled siRNA probes for tracking assembly and disassembly of siRNA nanocomplexes.
ACS nano 2012;6(7):6133-41.
2012: YongTae Kim; Omid C Farokhzad; Zahi A Fayad; Bomy Lee Chung; Mingming Ma; Willem J M Mulder; Robert Langer
Mass production and size control of lipid-polymer hybrid nanoparticles through controlled microvortices.
Nano letters 2012;12(7):3587-91.
2012: Hao Cheng; Nathaniel S Hwang; Christian J Kastrup; Robert Langer; Won Woo Lee; Matthias Nahrendorf; Albert K Tai; Xiaoyang Xu; Cathy T Zhang; Marta Byrska-Bishop; Daniel G Anderson
Stem cell membrane engineering for cell rolling using peptide conjugation and tuning of cell-selectin interaction kinetics.
Biomaterials 2012;33(20):5004-12.
2012: Avi Schroeder; Yingxia Wang; Michael S Goldberg; Shan Jiang; Brian J Joseph; Sneha T Kannan; Christian Kastrup; Robert Langer; Christopher G Levins; Daniel G Anderson
Remotely activated protein-producing nanoparticles.
Nano letters 2012;12(6):2685-9.
2012: Omar Z Fisher; David Graupner; Paulina S Hill; Nermin Seda Kehr; Robert Langer; Benjamin L Larson; Mai-Thi Nguyen-Kim; Luisa De Cola; Daniel G Anderson
Melanin-like hydrogels derived from gallic macromers.
Advanced materials (Deerfield Beach, Fla.) 2012;24(22):3032-6.
2012: Hyukjin Lee; Kevin T Love; Abigail K R Lytton-Jean; Muthiah Manoharan; Matthias Nahrendorf; Angela I Park; Chang G Peng; William Querbes; Alfica Sehgal; Jessica Truelove; Christopher S Zurenko; Anna Borodovsky; Klaus Charisse; Yi Chen; Jessica S Donahoe; Muthusamy Jayaraman; Emmanouil D Karagiannis; Robert Langer; Daniel G Anderson
Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery.
Nature nanotechnology 2012;7(6):389-93.
2012: Ana Jaklenec; Angela Sherwin; Andrea Stamp; Elizabeth Deweerd; Robert Langer
Progress in the tissue engineering and stem cell industry "are we there yet?".
Tissue engineering. Part B, Reviews 2012;18(3):155-66.
2012: Rong Tong; Robert Langer; Houman D Hemmati; Daniel S Kohane
Photoswitchable nanoparticles for triggered tissue penetration and drug delivery.
Journal of the American Chemical Society 2012;134(21):8848-55.
2012: Aleksandar F Radovic-Moreno; Christopher J Yoon; Robert Langer; Timothy K Lu; Vlad A Puscasu; Omid C Farokhzad
Surface charge-switching polymeric nanoparticles for bacterial cell wall-targeted delivery of antibiotics.
ACS nano 2012;6(5):4279-87.
2012: Kaitlin M Bratlie; Michael A Invernale; Robert Langer; Roger L York; Daniel G Anderson
Materials for diabetes therapeutics.
Advanced healthcare materials 2012;1(3):267-84.
2012: Ahmed A Eltoukhy; Robert Langer; Jay S Rajan; Daniel J Siegwart; Christopher A Alabi; Daniel G Anderson
Effect of molecular weight of amine end-modified poly(β-amino ester)s on gene delivery efficiency and toxicity.
Biomaterials 2012;33(13):3594-603.
2012: Iris Shichor; Noam Shomron; Janet Zoldan; Seul A Bae; Robert Langer; Michael W Lawlor; Daniel S Kohane
Toxicogenomic analysis of a sustained release local anesthetic delivery system.
Biomaterials 2012;33(13):3586-93.
2012: David N Nguyen; Alain P Vicari; Jianzhu Chen; Steve Chen; Ghania Chikh; Hattie Chung; Michael Goldberg; Phillip Kim; Arthur M Krieg; Robert Langer; Kevin T Love; Kerry P Mahon; Daniel G Anderson
Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(14):E797-803.
2012: Leon M Bellan; Donald M Cropek; Alla A Epshteyn; Ernest S Kim; Tatiana Kniazeva; Robert Langer; Jeffrey T Borenstein
Fabrication of a hybrid microfluidic system incorporating both lithographically patterned microchannels and a 3D fiber-formed microfluidic network.
Advanced healthcare materials 2012;1(2):164-7.
2012: Jennifer E Seto; Brett VanVeller; Robert Langer; Renata F V Lopez; Baris E Polat; Daniel Blankschtein
Fluorescent penetration enhancers for transdermal applications.
Journal of controlled release : official journal of the Controlled Release Society 2012;158(1):85-92.
2012: Zeyu Xiao; Frank Alexis; Juliana M Chan; Judy Cheng; Elise Digga; Robert Langer; Etgar Levy-Nissenbaum; Andrej Lupták; Jinjun Shi; Benjamin A Teply; Omid C Farokhzad
Engineering of targeted nanoparticles for cancer therapy using internalizing aptamers isolated by cell-uptake selection.
ACS nano 2012;6(1):696-704.
2012: Shuo Sun; Ming Wang; Daniel G Anderson; Xiao Hu; David L Kaplan; Sarah A Knupp; Robert Langer; Yadira Soto-Feliciano; Qiaobing Xu
Combinatorial library of lipidoids for in vitro DNA delivery.
Bioconjugate chemistry 2012;23(1):135-40.
2012: Juying Li; Huifei Liu; Kevin T Love; Jun S Song; Thanh-Nga T Tran; Daniel G Anderson; Robert J A Bell; Rizwan Haq; Robert Langer; Lionel Larue; David E Fisher
YY1 regulates melanocyte development and function by cooperating with MITF.
PLoS genetics 2012;8(5):e1002688.
2012: Andrew L Hook; Robert Langer; David J Scurr; Paul Williams; Jing Yang; Daniel G Anderson; Steve Atkinson; Chien-Yi Chang; Martyn C Davies; Morgan R Alexander
Polymer microarrays for high throughput discovery of biomaterials.
Journal of visualized experiments : JoVE 2012;(59):e3636.
2012: Zhuang Wang; Robert Langer; Omid C Farokhzad
Nanoparticle delivery of cancer drugs.
Annual review of medicine 2012;63():185-98.
2011: Janet Zoldan; Daniel G Anderson; Emmanouil D Karagiannis; Robert Langer; Christopher Y Lee; Shulamit Levenberg
The influence of scaffold elasticity on germ layer specification of human embryonic stem cells.
Biomaterials 2011;32(36):9612-21.
2011: Juliana M Chan; Chester L Drum; Gershon Golomb; Robert Langer; June-Wha Rhee; Roderick T Bronson; Omid C Farokhzad
In vivo prevention of arterial restenosis with paclitaxel-encapsulated targeted lipid-polymeric nanoparticles.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(48):19347-52.
2011: Tal Dvir; Hongwei Jin; Sandeep S Karajanagi; Robert Langer; Oren Levy; Shreesh R Naik; Kevin K Parker; Brian P Timko; Mark D Brigham; Daniel S Kohane
Nanowired three-dimensional cardiac patches.
Nature nanotechnology 2011;6(11):720-5.
2011: Nikita K Malavia; Amy M Princiotto; Avi Schroeder; Joseph Sodroski; David Zurakowski; Hila E Barash; Robert Langer; Anna R Laury; Navid Madani; Daniel S Kohane
Liposomes for HIV prophylaxis.
Biomaterials 2011;32(33):8663-8.
2011: Janet Zoldan; Leon M Bellan; Kaila Deiorio-Haggar; Emmanouil D Karagiannis; Robert Langer; Abigail K R Lytton-Jean; Daniel G Anderson
Directing human embryonic stem cell differentiation by non-viral delivery of siRNA in 3D culture.
Biomaterials 2011;32(31):7793-800.
2011: Tal Dvir; Daniel G Anderson; Michael Bauer; Robert Langer; Ronglih Liao; Avi Schroeder; Jonathan H Tsui; Daniel S Kohane
Nanoparticles targeting the infarcted heart.
Nano letters 2011;11(10):4411-4.
2011: Thomas P Kraehenbuehl; Robert Langer; Lino S Ferreira
Three-dimensional biomaterials for the study of human pluripotent stem cells.
Nature methods 2011;8(9):731-6.
2011: Liqiang Wang; David Zurakowski; Robert Langer; Irmgard Behlau; Homer H Chiang; James Chodosh; Claes H Dohlman; Kyung Jae Jeong; Daniel S Kohane
Hydroxyapatite for keratoprosthesis biointegration.
Investigative ophthalmology & visual science 2011;52(10):7392-9.
2011: Pedro M Valencia; Weiwei Gao; Mikhail H Hanewich-Hollatz; Fawziya Karim; Rohit Karnik; Robert Langer; Omid C Farokhzad
Effects of ligands with different water solubilities on self-assembly and properties of targeted nanoparticles.
Biomaterials 2011;32(26):6226-33.
2011: Halil Tekin; Tonia Tsinman; Gulden Camci-Unal; Brianna J Jones; Robert Langer; Jason W Nichol; Jefferson G Sanchez; Ali Khademhosseini
Responsive micromolds for sequential patterning of hydrogel microstructures.
Journal of the American Chemical Society 2011;133(33):12944-7.
2011: Daniel K Bonner; Jane Chen-Liang; Loice Chingozha; Robert Langer; Cheuk Leung; Paula T Hammond
Intracellular trafficking of polyamidoamine-poly(ethylene glycol) block copolymers in DNA delivery.
Bioconjugate chemistry 2011;22(8):1519-25.
2011: Daniel J Siegwart; Arturo Vegas; Kathryn A Whitehead; Christopher Zurenko; Hao Cheng; Sean P Collins; Christina Cortez; Patrick Fenton; Janice Jang; Shan Jiang; Robert Langer; Haeshin Lee; Christopher G Levins; Ying Fei Li; Kevin T Love; Abigail Lytton-Jean; Minglin Ma; Tatiana Novobrantseva; Lutz Nuhn; William Querbes; Gaurav Sahay; Daniel G Anderson
Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(32):12996-3001.
2011: Phillip A Sharp; Robert Langer
Research agenda. Promoting convergence in biomedical science.
Science (New York, N.Y.) 2011;333(6042):527.
2011: Tram T Dang; Kaitlin M Bratlie; Said R Bogatyrev; Xiao Y Chen; Robert Langer; Daniel G Anderson
Spatiotemporal effects of a controlled-release anti-inflammatory drug on the cellular dynamics of host response.
Biomaterials 2011;32(19):4464-70.
2011: Sandeep S Karajanagi; Roshan Yoganathan; Raffaella Mammucari; Hyoungshin Park; Julian Cox; Steven M Zeitels; Robert Langer; Neil R Foster
Application of a dense gas technique for sterilizing soft biomaterials.
Biotechnology and bioengineering 2011;108(7):1716-25.
2011: Fredrik Ghosh; Karin Arnér; William L Neeley; Robert Langer
Selective removal of photoreceptor cells in vivo using the biodegradable elastomer poly(glycerol sebacate).
Tissue engineering. Part A 2011;17(13-14):1675-82.
2011: Baris E Polat; Douglas Hart; Robert Langer; Daniel Blankschtein
Ultrasound-mediated transdermal drug delivery: mechanisms, scope, and emerging trends.
Journal of controlled release : official journal of the Controlled Release Society 2011;152(3):330-48.
2011: Nathaniel S Hwang; Sung Gap Im; Patrick B Wu; David A Bichara; Xing Zhao; Mark A Randolph; Robert Langer; Daniel G Anderson
Chondrogenic priming adipose-mesenchymal stem cells for cartilage tissue regeneration.
Pharmaceutical research 2011;28(6):1395-405.
2011: Halil Tekin; Gozde Ozaydin-Ince; Tonia Tsinman; Karen K Gleason; Robert Langer; Ali Khademhosseini; Melik C Demirel
Responsive microgrooves for the formation of harvestable tissue constructs.
Langmuir : the ACS journal of surfaces and colloids 2011;27(9):5671-9.
2011: Minsoung Rhee; Pedro M Valencia; Maria I Rodriguez; Robert Langer; Omid C Farokhzad; Rohit Karnik
Synthesis of size-tunable polymeric nanoparticles enabled by 3D hydrodynamic flow focusing in single-layer microchannels.
Advanced materials (Deerfield Beach, Fla.) 2011;23(12):H79-83.
2011: Hao Cheng; Paulina S Hill; Daniel J Siegwart; Nathaniel Vacanti; Abigail K R Lytton-Jean; Seung-Woo Cho; Anne Ye; Robert Langer; Daniel G Anderson
A novel family of biodegradable poly(ester amide) elastomers.
Advanced materials (Deerfield Beach, Fla.) 2011;23(12):H95-100.
2011: Sandeep S Karajanagi; Gerardo Lopez-Guerra; Hyoungshin Park; James B Kobler; Marilyn Galindo; Jon Aanestad; Daryush D Mehta; Yoshihiko Kumai; Nicholas Giordano; Anthony d'Almeida; James T Heaton; Robert Langer; Victoria L M Herrera; William Faquin; Robert E Hillman; Steven M Zeitels
Assessment of canine vocal fold function after injection of a new biomaterial designed to treat phonatory mucosal scarring.
The Annals of otology, rhinology, and laryngology 2011;120(3):175-84.
2011: Wendy F Liu; Minglin Ma; Kaitlin M Bratlie; Tram T Dang; Robert Langer; Daniel G Anderson
Real-time in vivo detection of biomaterial-induced reactive oxygen species.
Biomaterials 2011;32(7):1796-801.
2011: Christopher D Pritchard; Sven Crafoord; Sten Andréasson; Karin M Arnér; Timothy M O'Shea; Robert Langer; Fredrik K Ghosh
Evaluation of viscoelastic poly(ethylene glycol) sols as vitreous substitutes in an experimental vitrectomy model in rabbits.
Acta biomaterialia 2011;7(3):936-43.
2011: Hirokazu Kaji; Gulden Camci-Unal; Robert Langer; Ali Khademhosseini
Engineering systems for the generation of patterned co-cultures for controlling cell-cell interactions.
Biochimica et biophysica acta 2011;1810(3):239-50.
2011: Baris E Polat; Shangchao Lin; Jonathan D Mendenhall; Brett VanVeller; Robert Langer; Daniel Blankschtein
Experimental and molecular dynamics investigation into the amphiphilic nature of sulforhodamine B.
The journal of physical chemistry. B 2011;115(6):1394-402.
2011: Thomas Kraehenbuehl; Lino S Ferreira; Alison M Hayward; Matthias Nahrendorf; André J van der Vlies; Eliza Vasile; Ralph Weissleder; Robert Langer; Jeffrey A Hubbell
Human embryonic stem cell-derived microvascular grafts for cardiac tissue preservation after myocardial infarction.
Biomaterials 2011;32(4):1102-9.
2011: Baris E Polat; Pedro L Figueroa; Daniel Blankschtein; Robert Langer
Transport pathways and enhancement mechanisms within localized and non-localized transport regions in skin treated with low-frequency sonophoresis and sodium lauryl sulfate.
Journal of pharmaceutical sciences 2011;100(2):512-29.
2011: Tal Dvir; Brian P Timko; Daniel S Kohane; Robert Langer
Nanotechnological strategies for engineering complex tissues.
Nature nanotechnology 2011;6(1):13-22.
2011: Renata F V Lopez; Jennifer E Seto; Daniel Blankschtein; Robert Langer
Enhancing the transdermal delivery of rigid nanoparticles using the simultaneous application of ultrasound and sodium lauryl sulfate.
Biomaterials 2011;32(3):933-41.
2011: Christopher D Pritchard; Timothy M O'Shea; Daniel J Siegwart; Eliezer Calo; Daniel G Anderson; Francis M Reynolds; John A Thomas; Jonathan R Slotkin; Eric J Woodard; Robert Langer
An injectable thiol-acrylate poly(ethylene glycol) hydrogel for sustained release of methylprednisolone sodium succinate.
Biomaterials 2011;32(2):587-97.
2010: Baris E Polat; Daniel Blankschtein; Robert Langer
Low-frequency sonophoresis: application to the transdermal delivery of macromolecules and hydrophilic drugs.
Expert opinion on drug delivery 2010;7(12):1415-32.
2010: Martyn C Davies; Morgan R Alexander; Andrew L Hook; Jing Yang; Ying Mei; Michael Taylor; Andrew J Urquhart; Robert Langer; Daniel G Anderson
High throughput surface characterization: A review of a new tool for screening prospective biomedical material arrays.
Journal of drug targeting 2010;18(10):741-51.
2010: Jing Yang; Ying Mei; Andrew L Hook; Michael Taylor; Andrew J Urquhart; Said R Bogatyrev; Robert Langer; Daniel G Anderson; Martyn C Davies; Morgan R Alexander
Polymer surface functionalities that control human embryoid body cell adhesion revealed by high throughput surface characterization of combinatorial material microarrays.
Biomaterials 2010;31(34):8827-38.
2010: Ying Mei; Jennifer Hollister-Lock; Said R Bogatyrev; Seung-Woo Cho; Gordon C Weir; Robert Langer; Daniel G Anderson
A high throughput micro-array system of polymer surfaces for the manipulation of primary pancreatic islet cells.
Biomaterials 2010;31(34):8989-95.
2010: Christoffer K Abrahamsson; Fan Yang; Hyoungshin Park; Jonathan M Brunger; Piia Valonen; Robert Langer; Jean F Welter; Arnold I Caplan; Farshid Guilak; Lisa E Freed
Chondrogenesis and mineralization during in vitro culture of human mesenchymal stem cells on three-dimensional woven scaffolds.
Tissue engineering. Part A 2010;16(12):3709-18.
2010: Maxime D Guillemette; Hyoungshin Park; James C Hsiao; Saloni R Jain; Benjamin L Larson; Robert Langer; Lisa E Freed
Combined technologies for microfabricating elastomeric cardiac tissue engineering scaffolds.
Macromolecular bioscience 2010;10(11):1330-7.
2010: Yu-Hung Huang; Joseph A Cozzitorto; Nathan G Richards; Ahmed A Eltoukhy; Charles J Yeo; Robert Langer; Daniel G Anderson; Jonathan R Brody; Janet A Sawicki
CanScript, an 18-Base pair DNA sequence, boosts tumor cell-specific promoter activity: implications for targeted gene therapy.
Cancer biology & therapy 2010;10(9):878-84.
2010: N M Elman; B C Masi; Michael J Cima; Robert Langer
Electro-thermally induced structural failure actuator (ETISFA) for implantable controlled drug delivery devices based on micro-electro-mechanical-systems.
Lab on a chip 2010;10(20):2796-804.
2010: John M Maloney; Dessy Nikova; Franziska Lautenschläger; Emer Clarke; Robert Langer; Jochen Guck; Krystyn J Van Vliet
Mesenchymal stem cell mechanics from the attached to the suspended state.
Biophysical journal 2010;99(8):2479-87.
2010: Nagesh Kolishetti; shanta dhar; Pedro M Valencia; Lucy Q Lin; Rohit Karnik; Stephen J Lippard; Robert Langer; Omid C Farokhzad
Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(42):17939-44.
2010: Joost P Bruggeman; Christopher Bettinger; Robert Langer
Biodegradable xylitol-based elastomers: in vivo behavior and biocompatibility.
Journal of biomedical materials research. Part A 2010;95(1):92-104.
2010: Halil Tekin; Michael Anaya; Mark D Brigham; Claire Nauman; Robert Langer; Ali Khademhosseini
Stimuli-responsive microwells for formation and retrieval of cell aggregates.
Lab on a chip 2010;10(18):2411-8.
2010: Jinjun Shi; Alexander R Votruba; Omid C Farokhzad; Robert Langer
Nanotechnology in drug delivery and tissue engineering: from discovery to applications.
Nano letters 2010;10(9):3223-30.
2010: Weiwei Gao; Robert Langer; Omid C Farokhzad
Poly(ethylene glycol) with observable shedding.
Angewandte Chemie (International ed. in English) 2010;49(37):6567-71.
2010: Ying Mei; Krishanu Saha; Said R Bogatyrev; Jing Yang; Andrew L Hook; Z Ilke Kalcioglu; Seung-Woo Cho; Maisam Mitalipova; Neena Pyzocha; Fredrick Rojas; Krystyn J Van Vliet; Martyn C Davies; Morgan R Alexander; Robert Langer; Rudolf Jaenisch; Daniel G Anderson
Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells.
Nature materials 2010;9(9):768-78.
2010: Kerry P Mahon; Kevin T Love; Kathryn A Whitehead; June Qin; Akin Akinc; Elizaveta Leshchiner; Ignaty Leshchiner; Robert Langer; Daniel G Anderson
Combinatorial approach to determine functional group effects on lipidoid-mediated siRNA delivery.
Bioconjugate chemistry 2010;21(8):1448-54.
2010: Fan Yang; Seung-Woo Cho; Sun Mi Son; Sarah P Hudson; Said Bogatyrev; Lily Keung; Daniel S Kohane; Robert Langer; Daniel G Anderson
Combinatorial extracellular matrices for human embryonic stem cell differentiation in 3D.
Biomacromolecules 2010;11(8):1909-14.
2010: Hila Epstein-Barash; Gizem Orbey; Baris E Polat; Randy H Ewoldt; Jameel Feshitan; Robert Langer; Mark A Borden; Daniel S Kohane
A microcomposite hydrogel for repeated on-demand ultrasound-triggered drug delivery.
Biomaterials 2010;31(19):5208-17.
2010: Jennifer E Seto; Baris E Polat; Renata F V Lopez; Daniel Blankschtein; Robert Langer
Effects of ultrasound and sodium lauryl sulfate on the transdermal delivery of hydrophilic permeants: Comparative in vitro studies with full-thickness and split-thickness pig and human skin.
Journal of controlled release : official journal of the Controlled Release Society 2010;145(1):26-32.
2010: Shulamit Levenberg; Lino S Ferreira; Limor Chen-Konak; Thomas Kraehenbuehl; Robert Langer
Isolation, differentiation and characterization of vascular cells derived from human embryonic stem cells.
Nature protocols 2010;5(6):1115-26.
2010: Zhuang Wang; Kai Yuet; Liangfang Zhang; Frank X Gu; Minh Huynh-Le; Aleksandar F Radovic-Moreno; Philip W Kantoff; Neil H Bander; Robert Langer; Omid C Farokhzad
ChemoRad nanoparticles: a novel multifunctional nanoparticle platform for targeted delivery of concurrent chemoradiation.
Nanomedicine (London, England) 2010;5(3):361-8.
2010: Pedro M Valencia; Pamela A Basto; Liangfang Zhang; Minsoung Rhee; Robert Langer; Omid C Farokhzad; Rohit Karnik
Single-step assembly of homogenous lipid-polymeric and lipid-quantum dot nanoparticles enabled by microfluidic rapid mixing.
ACS nano 2010;4(3):1671-9.
2010: Mikhail G Shapiro; Gil G Westmeyer; Philip A Romero; Jerzy O Szablowski; Benedict Küster; Ameer Shah; Christopher R Otey; Robert Langer; Frances H Arnold; Alan Jasanoff
Directed evolution of a magnetic resonance imaging contrast agent for noninvasive imaging of dopamine.
Nature biotechnology 2010;28(3):264-70.
2010: Fan Yang; Seung-Woo Cho; Sun Mi Son; Said R Bogatyrev; Deepika Singh; Jordan Green; Ying Mei; Sohyun Park; Suk Ho Bhang; Byung-Soo Kim; Robert Langer; Daniel G Anderson
Genetic engineering of human stem cells for enhanced angiogenesis using biodegradable polymeric nanoparticles.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(8):3317-22.
2010: Juliana M Chan; Liangfang Zhang; Rong Tong; Debuyati Ghosh; Weiwei Gao; Grace Liao; Kai P Yuet; David Gray; June-Wha Rhee; Jianjun Cheng; Gershon Golomb; Peter Libby; Robert Langer; Omid C Farokhzad
Spatiotemporal controlled delivery of nanoparticles to injured vasculature.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(5):2213-8.
2010: Kevin T Love; Kerry P Mahon; Christopher G Levins; Kathryn A Whitehead; William Querbes; J Robert Dorkin; June Qin; William Cantley; Liu-liang Qin; Timothy Racie; Maria Frank-Kamenetsky; Ka Ning Yip; Rene Alvarez; Dinah W Y Sah; Antonin de Fougerolles; Kevin Fitzgerald; Victor E Koteliansky; Akin Akinc; Robert Langer; Daniel G Anderson
Lipid-like materials for low-dose, in vivo gene silencing.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(5):1864-9.
2010: Tewodros Mamo; E Ashley Moseman; Nagesh Kolishetti; Carolina Salvador-Morales; Jinjun Shi; Daniel R Kuritzkes; Robert Langer; Ulrich von Andrian; Omid C Farokhzad
Emerging nanotechnology approaches for HIV/AIDS treatment and prevention.
Nanomedicine (London, England) 2010;5(2):269-85.
2010: Sarah P Hudson; Robert Langer; Gerald R Fink; Daniel S Kohane
Injectable in situ cross-linking hydrogels for local antifungal therapy.
Biomaterials 2010;31(6):1444-52.
2010: Todd J Harris; Jordan Green; Peter W Fung; Robert Langer; Daniel G Anderson; Sangeeta N Bhatia
Tissue-specific gene delivery via nanoparticle coating.
Biomaterials 2010;31(5):998-1006.
2010: Todd Hoare; David Zurakowski; Robert Langer; Daniel S Kohane
Rheological blends for drug delivery. I. Characterization in vitro.
Journal of biomedical materials research. Part A 2010;92(2):575-85.
2010: Weiwei Gao; Zeyu Xiao; Alex Radovic-Moreno; Jinjun Shi; Robert Langer; Omid C Farokhzad
Progress in siRNA delivery using multifunctional nanoparticles.
Methods in molecular biology (Clifton, N.J.) 2010;629():53-67.
2010: Kaitlin M Bratlie; Tram T Dang; Stephen Lyle; Matthias Nahrendorf; Ralph Weissleder; Robert Langer; Daniel G Anderson
Rapid biocompatibility analysis of materials via in vivo fluorescence imaging of mouse models.
PloS one 2010;5(4):e10032.
2010: Juliana M Chan; Pedro M Valencia; Liangfang Zhang; Robert Langer; Omid C Farokhzad
Polymeric nanoparticles for drug delivery.
Methods in molecular biology (Clifton, N.J.) 2010;624():163-75.
2010: Frank Alexis; Eric M Pridgen; Robert Langer; Omid C Farokhzad
Nanoparticle technologies for cancer therapy.
Handbook of experimental pharmacology 2010;(197):55-86.
2010: A Schroeder; C G Levins; C Cortez; Robert Langer; Daniel G Anderson
Lipid-based nanotherapeutics for siRNA delivery.
Journal of internal medicine 2010;267(1):9-21.
2010: Sharon Gerecht; Lino S Ferreira; Robert Langer
Vascular differentiation of human embryonic stem cells in bioactive hydrogel-based scaffolds.
Methods in molecular biology (Clifton, N.J.) 2010;584():333-54.
2010: Tal Dvir; Matthew R Banghart; Brian P Timko; Robert Langer; Daniel S Kohane
Photo-targeted nanoparticles.
Nano letters 2010;10(1):250-4.
2010: Andrew L Hook; Daniel G Anderson; Robert Langer; Paul Williams; Martyn C Davies; Morgan R Alexander
High throughput methods applied in biomaterial development and discovery.
Biomaterials 2010;31(2):187-98.
2009: Christopher Bettinger; Joost P Bruggeman; Jeffrey Borenstein; Robert Langer
In vitro and in vivo degradation of poly(1,3-diamino-2-hydroxypropane-co-polyol sebacate) elastomers.
Journal of biomedical materials research. Part A 2009;91(4):1077-88.
2009: Tram T Dang; Qiaobing Xu; Kaitlin M Bratlie; Esther S O'Sullivan; Xiao Y Chen; Robert Langer; Daniel G Anderson
Microfabrication of homogenous, asymmetric cell-laden hydrogel capsules.
Biomaterials 2009;30(36):6896-902.
2009: Paul M George; Rajiv Saigal; Michael W Lawlor; Michael J Moore; David A LaVan; Robert P Marini; Martin Selig; Melvin Makhni; Jason A Burdick; Robert Langer; Daniel S Kohane
Three-dimensional conductive constructs for nerve regeneration.
Journal of biomedical materials research. Part A 2009;91(2):519-27.
2009: Robert Langer
Perspectives and challenges in tissue engineering and regenerative medicine.
Advanced materials (Deerfield Beach, Fla.) 2009;21(32-33):3235-6.
2009: David N Nguyen; Steve C-Y Chen; James Lu; Michael Goldberg; Phillip Kim; Andrew Sprague; Tatiana Novobrantseva; Jennifer Sherman; Svetlana Shulga-Morskaya; Antonin de Fougerolles; Jianzhu Chen; Robert Langer; Daniel G Anderson
Drug delivery-mediated control of RNA immunostimulation.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(9):1555-62.
2009: Thomas Kraehenbuehl; Lino S Ferreira; Prisca Zammaretti; Jeffrey A Hubbell; Robert Langer
Cell-responsive hydrogel for encapsulation of vascular cells.
Biomaterials 2009;30(26):4318-24.
2009: Yu-Hung Huang; Gregory T Zugates; Weidan Peng; David Holtz; Charles Dunton; Jordan Green; Naushad Hossain; Michael R Chernick; Robert F Padera; Robert Langer; Daniel G Anderson; Janet A Sawicki
Nanoparticle-delivered suicide gene therapy effectively reduces ovarian tumor burden in mice.
Cancer research 2009;69(15):6184-91.
2009: Karen D Daniel; Grace Y Kim; Christophoros C Vassiliou; Marilyn Galindo; Alexander R Guimaraes; Ralph Weissleder; Al Charest; Robert Langer; Michael J Cima
Implantable diagnostic device for cancer monitoring.
Biosensors & bioelectronics 2009;24(11):3252-7.
2009: Fan Yang; Ying Mei; Robert Langer; Daniel G Anderson
High throughput optimization of stem cell microenvironments.
Combinatorial chemistry & high throughput screening 2009;12(6):554-61.
2009: Stephen Redenti; William L Neeley; Santiago Rompani; Sunita Saigal; Jing Yang; Henry Klassen; Robert Langer; Michael J Young
Engineering retinal progenitor cell and scrollable poly(glycerol-sebacate) composites for expansion and subretinal transplantation.
Biomaterials 2009;30(20):3405-14.
2009: David N Nguyen; Phillip Kim; Luis Martinez-Sobrido; Brett Beitzel; Adolfo García-Sastre; Robert Langer; Daniel G Anderson
A novel high-throughput cell-based method for integrated quantification of type I interferons and in vitro screening of immunostimulatory RNA drug delivery.
Biotechnology and bioengineering 2009;103(4):664-75.
2009: Qiaobing Xu; Michinao Hashimoto; Tram T Dang; Todd Hoare; Daniel S Kohane; George M Whitesides; Robert Langer; Daniel G Anderson
Preparation of monodisperse biodegradable polymer microparticles using a microfluidic flow-focusing device for controlled drug delivery.
Small (Weinheim an der Bergstrasse, Germany) 2009;5(13):1575-81.
2009: Jae-Seung Lee; Jordan Green; Kevin T Love; Joel Sunshine; Robert Langer; Daniel G Anderson
Gold, poly(beta-amino ester) nanoparticles for small interfering RNA delivery.
Nano letters 2009;9(6):2402-6.
2009: Christopher Bettinger; Katherine M Kulig; Joseph P Vacanti; Robert Langer; Jeffrey Borenstein
Nanofabricated collagen-inspired synthetic elastomers for primary rat hepatocyte culture.
Tissue engineering. Part A 2009;15(6):1321-9.
2009: James J Lu; Robert Langer; Jianzhu Chen
A novel mechanism is involved in cationic lipid-mediated functional siRNA delivery.
Molecular pharmaceutics 2009;6(3):763-71.
2009: Akin Akinc; Michael Goldberg; June Qin; J Robert Dorkin; Christina Gamba-Vitalo; Martin Maier; K Narayanannair Jayaprakash; Muthusamy Jayaraman; Kallanthottathil G Rajeev; Muthiah Manoharan; Victor Koteliansky; Ingo Röhl; Elizaveta S Leshchiner; Robert Langer; Daniel G Anderson
Development of lipidoid-siRNA formulations for systemic delivery to the liver.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(5):872-9.
2009: Carolina Salvador-Morales; Liangfang Zhang; Robert Langer; Omid C Farokhzad
Immunocompatibility properties of lipid-polymer hybrid nanoparticles with heterogeneous surface functional groups.
Biomaterials 2009;30(12):2231-40.
2009: F Yang; Jordan Green; T Dinio; L Keung; Seung-Woo Cho; Hyoungshin Park; Robert Langer; Daniel G Anderson
Gene delivery to human adult and embryonic cell-derived stem cells using biodegradable nanoparticulate polymeric vectors.
Gene therapy 2009;16(4):533-46.
2009: Juliana M Chan; Liangfang Zhang; Kai P Yuet; Grace Liao; June-Wha Rhee; Robert Langer; Omid C Farokhzad
PLGA-lecithin-PEG core-shell nanoparticles for controlled drug delivery.
Biomaterials 2009;30(8):1627-34.
2009: Mikhail G Shapiro; Jerzy O Szablowski; Robert Langer; Alan Jasanoff
Protein nanoparticles engineered to sense kinase activity in MRI.
Journal of the American Chemical Society 2009;131(7):2484-6.
2009: Carolina Salvador-Morales; Weiwei Gao; Pooja Ghatalia; Farhan Murshed; Wataru Aizu; Robert Langer; Omid C Farokhzad
Multifunctional nanoparticles for prostate cancer therapy.
Expert review of anticancer therapy 2009;9(2):211-21.
2009: Kathryn A Whitehead; Robert Langer; Daniel G Anderson
Knocking down barriers: advances in siRNA delivery.
Nature reviews. Drug discovery 2009;8(2):129-38.
2009: Geoffrey Stone; Suzanne Barzee; Victoria Snarsky; Camila Santucci; Brian Tran; Robert Langer; Gregory T Zugates; Daniel G Anderson; Richard Kornbluth
Nanoparticle-delivered multimeric soluble CD40L DNA combined with Toll-Like Receptor agonists as a treatment for melanoma.
PloS one 2009;4(10):e7334.
2009: Christopher J Bettinger; Robert Langer; Jeffrey T Borenstein
Engineering substrate topography at the micro- and nanoscale to control cell function.
Angewandte Chemie (International ed. in English) 2009;48(30):5406-15.
2009: Frank Gu; Robert Langer; Omid C Farokhzad
Formulation/preparation of functionalized nanoparticles for in vivo targeted drug delivery.
Methods in molecular biology (Clifton, N.J.) 2009;544():589-98.
2008: Liangfang Zhang; Juliana M Chan; Frank X Gu; June-Wha Rhee; Zhuang Wang; Aleksandar F Radovic-Moreno; Frank Alexis; Robert Langer; Omid C Farokhzad
Self-assembled lipid--polymer hybrid nanoparticles: a robust drug delivery platform.
ACS nano 2008;2(8):1696-702.
2008: Saba Parsa; Yong Wang; Jason Fuller; Robert Langer; Blaine A Pfeifer
A comparison between polymeric microsphere and bacterial vectors for macrophage P388D1 gene delivery.
Pharmaceutical research 2008;25(5):1202-8.
2008: L Zhang; Frank X Gu; J M Chan; Zhuang Wang; Robert Langer; Omid C Farokhzad
Nanoparticles in medicine: therapeutic applications and developments.
Clinical pharmacology and therapeutics 2008;83(5):761-9.
2008: Dylan Wright; Bimalraj Rajalingam; jeff karp; Selvapraba Selvarasah; Yibo Ling; Judy Yeh; Robert Langer; Mehmet R Dokmeci; Ali Khademhosseini
Reusable, reversibly sealable parylene membranes for cell and protein patterning.
Journal of biomedical materials research. Part A 2008;85(2):530-8.
2008: Rohit Karnik; Seungpyo Hong; Huanan Zhang; Ying Mei; Daniel G Anderson; jeff karp; Robert Langer
Nanomechanical control of cell rolling in two dimensions through surface patterning of receptors.
Nano letters 2008;8(4):1153-8.
2008: Alborz Mahdavi; Lino Ferreira; Cathryn Sundback; Jason W Nichol; Edwin P Chan; David J D Carter; Christopher Bettinger; Siamrut Patanavanich; Loice Chignozha; Eli Ben-Joseph; Alex Galakatos; Howard Pryor; Irina Pomerantseva; Peter T Masiakos; William Faquin; Andreas Zumbuehl; Seungpyo Hong; Jeffrey Borenstein; Joseph P Vacanti; Robert Langer; jeff karp
A biodegradable and biocompatible gecko-inspired tissue adhesive.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2307-12.
2008: Frank Gu; Liangfang Zhang; Benjamin A Teply; Nina Mann; Andrew Zhuang Wang; Aleksandar F Radovic-Moreno; Robert Langer; Omid C Farokhzad
Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2586-91.
2008: Kris C Wood; Samira M Azarin; Wadih Arap; Renata Pasqualini; Robert Langer; Paula T Hammond
Tumor-targeted gene delivery using molecularly engineered hybrid polymers functionalized with a tumor-homing peptide.
Bioconjugate chemistry 2008;19(2):403-5.
2008: William L Neeley; Stephen Redenti; Henry Klassen; Sarah Tao; Tejal Desai; Michael J Young; Robert Langer
A microfabricated scaffold for retinal progenitor cell grafting.
Biomaterials 2008;29(4):418-26.
2008: Joseph Kushner; Daniel Blankschtein; Robert Langer
Evaluation of hydrophilic permeant transport parameters in the localized and non-localized transport regions of skin treated simultaneously with low-frequency ultrasound and sodium lauryl sulfate.
Journal of pharmaceutical sciences 2008;97(2):906-18.
2008: Lifeng Kang; Bong Geun Chung; Robert Langer; Ali Khademhosseini
Microfluidics for drug discovery and development: from target selection to product lifecycle management.
Drug discovery today 2008;13(1-2):1-13.
2008: Frank Alexis; June-Wha Rhee; Jerome P Richie; Aleksandar F Radovic-Moreno; Robert Langer; Omid C Farokhzad
New frontiers in nanotechnology for cancer treatment.
Urologic oncology 2008;26(1):74-85.
2007: Dana R Adams; Mehmet Toner; Robert Langer
Role of trehalose in prevention of giant vesicle adsorption and encapsulated solute leakage in anhydrobiotic preservation.
Langmuir : the ACS journal of surfaces and colloids 2007;23(26):13013-23.
2007: Joseph Kushner; Daniel Blankschtein; Robert Langer
Evaluation of the porosity, the tortuosity, and the hindrance factor for the transdermal delivery of hydrophilic permeants in the context of the aqueous pore pathway hypothesis using dual-radiolabeled permeability experiments.
Journal of pharmaceutical sciences 2007;96(12):3263-82.
2007: Joseph Kushner; William Deen; Daniel Blankschtein; Robert Langer
First-principles, structure-based transdermal transport model to evaluate lipid partition and diffusion coefficients of hydrophobic permeants solely from stratum corneum permeation experiments.
Journal of pharmaceutical sciences 2007;96(12):3236-51.
2007: Oleg V Evgenov; Daniel S Kohane; Kenneth D Bloch; Johannes-Peter Stasch; Gian P Volpato; Evangelia Bellas; Natalia V Evgenov; Emmanuel Buys; Mark J Gnoth; Amanda R Graveline; Rong Liu; Dean R Hess; Robert Langer; Warren M Zapol
Inhaled agonists of soluble guanylate cyclase induce selective pulmonary vasodilation.
American journal of respiratory and critical care medicine 2007;176(11):1138-45.
2007: Seth Townsend; Gilad D Evrony; Frank X Gu; Martin P Schulz; Robert H Brown; Robert Langer
Tetanus toxin C fragment-conjugated nanoparticles for targeted drug delivery to neurons.
Biomaterials 2007;28(34):5176-84.
2007: Ali Khademhosseini; Robert Langer
Microengineered hydrogels for tissue engineering.
Biomaterials 2007;28(34):5087-92.
2007: Seungpyo Hong; Dooyoung Lee; Huanan Zhang; Jennifer Q Zhang; Jennifer N Resvick; Ali Khademhosseini; Michael King; Robert Langer; jeff karp
Covalent immobilization of p-selectin enhances cell rolling.
Langmuir : the ACS journal of surfaces and colloids 2007;23(24):12261-8.
2007: Gregory T Zugates; Nathan C Tedford; Andreas Zumbuehl; Siddharth Jhunjhunwala; Christina S Kang; Linda G Griffith; Douglas A Lauffenburger; Robert Langer; Daniel G Anderson
Gene delivery properties of end-modified poly(beta-amino ester)s.
Bioconjugate chemistry 2007;18(6):1887-96.
2007: Grace Y Kim; Lee Josephson; Robert Langer; Michael J Cima
Magnetic relaxation switch detection of human chorionic gonadotrophin.
Bioconjugate chemistry 2007;18(6):2024-8.
2007: Sharon Gerecht; Seth Townsend; Heather Pressler; Han Zhu; Christiaan L E Nijst; Joost P Bruggeman; Jason W Nichol; Robert Langer
A porous photocurable elastomer for cell encapsulation and culture.
Biomaterials 2007;28(32):4826-35.
2007: Matthias John; Rainer Constien; Akin Akinc; Michael Goldberg; Young-Ah Moon; Martina Spranger; Philipp Hadwiger; juergen soutschek; Hans-Peter Vornlocher; Muthiah Manoharan; Markus Stoffel; Robert Langer; Daniel G Anderson; Jay D Horton; Victor E Koteliansky; David Bumcrot
Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway.
Nature 2007;449(7163):745-7.
2007: jeff karp; Robert Langer
Development and therapeutic applications of advanced biomaterials.
Current opinion in biotechnology 2007;18(5):454-9.
2007: Karen D Daniel; Grace Y Kim; Christophoros C Vassiliou; Farzad Jalali-Yazdi; Robert Langer; Michael J Cima
Multi-reservoir device for detecting a soluble cancer biomarker.
Lab on a chip 2007;7(10):1288-93.
2007: Vaishali Bagalkot; Liangfang Zhang; Etgar Levy-Nissenbaum; Sangyong Jon; Philip W Kantoff; Robert Langer; Omid C Farokhzad
Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer.
Nano letters 2007;7(10):3065-70.
2007: Christiaan L E Nijst; Joost P Bruggeman; jeff karp; Lino Ferreira; Andreas Zumbuehl; Christopher Bettinger; Robert Langer
Synthesis and characterization of photocurable elastomers from poly(glycerol-co-sebacate).
Biomacromolecules 2007;8(10):3067-73.
2007: Sharon Gerecht; Christopher Bettinger; Zhitong Zhang; Jeffrey T Borenstein; Gordana Vunjak-Novakovic; Robert Langer
The effect of actin disrupting agents on contact guidance of human embryonic stem cells.
Biomaterials 2007;28(28):4068-77.
2007: Yoon Yeo; Evangelia Bellas; Christopher B Highley; Robert Langer; Daniel S Kohane
Peritoneal adhesion prevention with an in situ cross-linkable hyaluronan gel containing tissue-type plasminogen activator in a rabbit repeated-injury model.
Biomaterials 2007;28(25):3704-13.
2007: Milica Radisic; Hyoungshin Park; Sharon Gerecht; Christopher Cannizzaro; Robert Langer; Gordana Vunjak-Novakovic
Biomimetic approach to cardiac tissue engineering.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2007;362(1484):1357-68.
2007: Andreas Zumbuehl; Lino Ferreira; Duncan Kuhn; Anna Astashkina; Lisa Long; Yoon Yeo; Tiffany Iaconis; Mahmoud Ghannoum; Gerald R Fink; Robert Langer; Daniel S Kohane
Antifungal hydrogels.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(32):12994-8.
2007: Lino S Ferreira; Sharon Gerecht; Hester F Shieh; Nicki Watson; Maria A Rupnick; Susan M Dallabrida; Gordana Vunjak-Novakovic; Robert Langer
Vascular progenitor cells isolated from human embryonic stem cells give rise to endothelial and smooth muscle like cells and form vascular networks in vivo.
Circulation research 2007;101(3):286-94.
2007: Hyoungshin Park; Christopher Cannizzaro; Gordana Vunjak-Novakovic; Robert Langer; Charles A Vacanti; Omid C Farokhzad
Nanofabrication and microfabrication of functional materials for tissue engineering.
Tissue engineering 2007;13(8):1867-77.
2007: Shulamit Levenberg; Janet Zoldan; Yaara Basevitch; Robert Langer
Endothelial potential of human embryonic stem cells.
Blood 2007;110(3):806-14.
2007: Sharon Gerecht; Jason A Burdick; Lino S Ferreira; Seth Townsend; Robert Langer; Gordana Vunjak-Novakovic
Hyaluronic acid hydrogel for controlled self-renewal and differentiation of human embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(27):11298-303.
2007: Gregory T Zugates; Weidan Peng; Andreas Zumbuehl; Siddharth Jhunjhunwala; Yu-Hung Huang; Robert Langer; Janet A Sawicki; Daniel G Anderson
Rapid optimization of gene delivery by parallel end-modification of poly(beta-amino ester)s.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(7):1306-12.
2007: jeff karp; Judy Yeh; George Eng; Junji Fukuda; James Blumling; Kahp Y Suh; Jianjun Cheng; Alborz Mahdavi; Jeffrey Borenstein; Robert Langer; Ali Khademhosseini
Controlling size, shape and homogeneity of embryoid bodies using poly(ethylene glycol) microwells.
Lab on a chip 2007;7(6):786-94.
2007: Elisa Figallo; Christopher Cannizzaro; Sharon Gerecht; Jason A Burdick; Robert Langer; Nicola Elvassore; Gordana Vunjak-Novakovic
Micro-bioreactor array for controlling cellular microenvironments.
Lab on a chip 2007;7(6):710-9.
2007: Lino S Ferreira; Sharon Gerecht; Jason Fuller; Hester F Shieh; Gordana Vunjak-Novakovic; Robert Langer
Bioactive hydrogel scaffolds for controllable vascular differentiation of human embryonic stem cells.
Biomaterials 2007;28(17):2706-17.
2007: Jordan Green; Eugene Chiu; Elizaveta S Leshchiner; Julie Shi; Robert Langer; Daniel G Anderson
Electrostatic ligand coatings of nanoparticles enable ligand-specific gene delivery to human primary cells.
Nano letters 2007;7(4):874-9.
2007: Ali Khademhosseini; George Eng; Judy Yeh; Peter A Kucharczyk; Robert Langer; Gordana Vunjak-Novakovic; Milica Radisic
Microfluidic patterning for fabrication of contractile cardiac organoids.
Biomedical microdevices 2007;9(2):149-57.
2007: Elena Choleris; Steven R Little; Jessica Mong; Sidharth V Puram; Robert Langer; Donald Pfaff
Microparticle-based delivery of oxytocin receptor antisense DNA in the medial amygdala blocks social recognition in female mice.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(11):4670-5.
2007: M S Ward; khoobehi ali; Erin Lavik; Robert Langer; Michael J Young
Neuroprotection of retinal ganglion cells in DBA/2J mice with GDNF-loaded biodegradable microspheres.
Journal of pharmaceutical sciences 2007;96(3):558-68.
2007: Jianjun Cheng; Benjamin A Teply; Ines Sherifi; Josephine Sung; Gaurav Luther; Frank X Gu; Etgar Levy-Nissenbaum; Aleksandar F Radovic-Moreno; Robert Langer; Omid C Farokhzad
Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery.
Biomaterials 2007;28(5):869-76.
2007: Caihui Jiang; Michael J Moore; Xinmei Zhang; Henry Klassen; Robert Langer; Michael Young
Intravitreal injections of GDNF-loaded biodegradable microspheres are neuroprotective in a rat model of glaucoma.
Molecular vision 2007;13():1783-92.
2007: Michael Goldberg; Robert Langer; Xinqiao Jia
Nanostructured materials for applications in drug delivery and tissue engineering.
Journal of biomaterials science. Polymer edition 2007;18(3):241-68.
2006: Vaishali Bagalkot; Omid C Farokhzad; Robert Langer; Sangyong Jon
An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform.
Angewandte Chemie (International ed. in English) 2006;45(48):8149-52.
2006: Ying Luo; James B Kobler; Steven M Zeitels; Robert Langer
Effects of growth factors on extracellular matrix production by vocal fold fibroblasts in 3-dimensional culture.
Tissue engineering 2006;12(12):3365-74.
2006: Xinqiao Jia; Yoon Yeo; Rodney J Clifton; Tong Jiao; Daniel S Kohane; James B Kobler; Steven M Zeitels; Robert Langer
Hyaluronic acid-based microgels and microgel networks for vocal fold regeneration.
Biomacromolecules 2006;7(12):3336-44.
2006: Ali Khademhosseini; Lino Ferreira; James Blumling; Judy Yeh; jeff karp; Junji Fukuda; Robert Langer
Co-culture of human embryonic stem cells with murine embryonic fibroblasts on microwell-patterned substrates.
Biomaterials 2006;27(36):5968-77.
2006: Ali Khademhosseini; George Eng; Judy Yeh; Junji Fukuda; James Blumling; Robert Langer; Jason A Burdick
Micromolding of photocrosslinkable hyaluronic acid for cell encapsulation and entrapment.
Journal of biomedical materials research. Part A 2006;79(3):522-32.
2006: Judy Yeh; Yibo Ling; jeff karp; Jay Gantz; Akash Chandawarkar; George Eng; James Blumling; Robert Langer; Ali Khademhosseini
Micromolding of shape-controlled, harvestable cell-laden hydrogels.
Biomaterials 2006;27(31):5391-8.
2006: Gregory T Zugates; Daniel G Anderson; Steven R Little; Ingrid E B Lawhorn; Robert Langer
Synthesis of poly(beta-amino ester)s with thiol-reactive side chains for DNA delivery.
Journal of the American Chemical Society 2006;128(39):12726-34.
2006: Sandra Hofmann; Sven Knecht; Robert Langer; David L Kaplan; Gordana Vunjak-Novakovic; Hans P Merkle; Lorenz Meinel
Cartilage-like tissue engineering using silk scaffolds and mesenchymal stem cells.
Tissue engineering 2006;12(10):2729-38.
2006: Junji Fukuda; Ali Khademhosseini; Yoon Yeo; Xiaoyu Yang; Judy Yeh; George Eng; James Blumling; Chi-Fong Wang; Daniel S Kohane; Robert Langer
Micromolding of photocrosslinkable chitosan hydrogel for spheroid microarray and co-cultures.
Biomaterials 2006;27(30):5259-67.
2006: Lorenz Meinel; Sandra Hofmann; Oliver Betz; Robert Fajardo; Hans P Merkle; Robert Langer; Christopher H Evans; Gordana Vunjak-Novakovic; David L Kaplan
Osteogenesis by human mesenchymal stem cells cultured on silk biomaterials: comparison of adenovirus mediated gene transfer and protein delivery of BMP-2.
Biomaterials 2006;27(28):4993-5002.
2006: Lorenz Meinel; Oliver Betz; Robert Fajardo; Sandra Hofmann; A Nazarian; E Cory; Monika Hilbe; John McCool; Robert Langer; Gordana Vunjak-Novakovic; Hans P Merkle; B Rechenberg; David L Kaplan; Carl A Kirker-Head
Silk based biomaterials to heal critical sized femur defects.
Bone 2006;39(4):922-31.
2006: David Berry; David M Lynn; Eric Berry; Ram Sasisekharan; Robert Langer
Heparin localization and fine structure regulate Burkitt's lymphoma growth.
Biochemical and biophysical research communications 2006;348(3):850-6.
2006: Yoon Yeo; Jason A Burdick; Christopher B Highley; Robert Marini; Robert Langer; Daniel S Kohane
Peritoneal application of chitosan and UV-cross-linkable chitosan.
Journal of biomedical materials research. Part A 2006;78(4):668-75.
2006: Omid C Farokhzad; Jordan D Dimitrakov; jeff karp; Ali Khademhosseini; Michael R Freeman; Robert Langer
Drug delivery systems in urology--getting "smarter".
Urology 2006;68(3):463-9.
2006: Jordan Green; Julie Shi; Eugene Chiu; Elizaveta S Leshchiner; Robert Langer; Daniel G Anderson
Biodegradable polymeric vectors for gene delivery to human endothelial cells.
Bioconjugate chemistry 2006;17(5):1162-9.
2006: Yoon Yeo; Christopher B Highley; Evangelia Bellas; Taichi Ito; Robert Marini; Robert Langer; Daniel S Kohane
In situ cross-linkable hyaluronic acid hydrogels prevent post-operative abdominal adhesions in a rabbit model.
Biomaterials 2006;27(27):4698-705.
2006: Milica Radisic; Hyoungshin Park; Fen Chen; Johanna E Salazar-Lazzaro; Yadong Wang; Robert Dennis; Robert Langer; Lisa E Freed; Gordana Vunjak-Novakovic
Biomimetic approach to cardiac tissue engineering: oxygen carriers and channeled scaffolds.
Tissue engineering 2006;12(8):2077-91.
2006: Kahp Y Suh; Ali Khademhosseini; Sangyong Jon; Robert Langer
Direct confinement of individual viruses within polyethylene glycol (PEG) nanowells.
Nano letters 2006;6(6):1196-201.
2006: Omid C Farokhzad; jeff karp; Robert Langer
Nanoparticle-aptamer bioconjugates for cancer targeting.
Expert opinion on drug delivery 2006;3(3):311-24.
2006: Daniel S Kohane; Julie Y Tse; Yoon Yeo; Robert F Padera; Maria Shubina; Robert Langer
Biodegradable polymeric microspheres and nanospheres for drug delivery in the peritoneum.
Journal of biomedical materials research. Part A 2006;77(2):351-61.
2006: Omid C Farokhzad; Jianjun Cheng; Benjamin A Teply; Ines Sherifi; Sangyong Jon; Philip W Kantoff; Jerome P Richie; Robert Langer
Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(16):6315-20.
2006: Ying Chau; Robert F Padera; Natalie M Dang; Robert Langer
Antitumor efficacy of a novel polymer-peptide-drug conjugate in human tumor xenograft models.
International journal of cancer. Journal international du cancer 2006;118(6):1519-26.
2006: Mariah S Hahn; James B Kobler; Steven M Zeitels; Robert Langer
Quantitative and comparative studies of the vocal fold extracellular matrix II: collagen.
The Annals of otology, rhinology, and laryngology 2006;115(3):225-32.
2006: Ying Chau; Natalie M Dang; Frederick E Tan; Robert Langer
Investigation of targeting mechanism of new dextran-peptide-methotrexate conjugates using biodistribution study in matrix-metalloproteinase-overexpressing tumor xenograft model.
Journal of pharmaceutical sciences 2006;95(3):542-51.
2006: Junji Fukuda; Ali Khademhosseini; Judy Yeh; George Eng; Jianjun Cheng; Omid C Farokhzad; Robert Langer
Micropatterned cell co-cultures using layer-by-layer deposition of extracellular matrix components.
Biomaterials 2006;27(8):1479-86.
2006: Mariah S Hahn; Benjamin A Teply; Molly M Stevens; Steven M Zeitels; Robert Langer
Collagen composite hydrogels for vocal fold lamina propria restoration.
Biomaterials 2006;27(7):1104-9.
2006: Ali Khademhosseini; Robert Langer; Jeffrey Borenstein; Joseph P Vacanti
Microscale technologies for tissue engineering and biology.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(8):2480-7.
2006: Milica Radisic; Jos Malda; Eric Epping; Wenliang Geng; Robert Langer; Gordana Vunjak-Novakovic
Oxygen gradients correlate with cell density and cell viability in engineered cardiac tissue.
Biotechnology and bioengineering 2006;93(2):332-43.
2006: Philip Lee; Naina Ahmad; Robert Langer; Samir Mitragotri; V Prasad Shastri
Evaluation of chemical enhancers in the transdermal delivery of lidocaine.
International journal of pharmaceutics 2006;308(1-2):33-9.
2006: Mariah S Hahn; James B Kobler; Barry Starcher; Steven M Zeitels; Robert Langer
Quantitative and comparative studies of the vocal fold extracellular matrix. I: Elastic fibers and hyaluronic acid.
The Annals of otology, rhinology, and laryngology 2006;115(2):156-64.
2006: Ali Khademhosseini; Chris Bettinger; jeff karp; Judy Yeh; Yibo Ling; Jeffrey Borenstein; Junji Fukuda; Robert Langer
Interplay of biomaterials and micro-scale technologies for advancing biomedical applications.
Journal of biomaterials science. Polymer edition 2006;17(11):1221-40.
2006: Sharon Gerecht-Nir; Milica Radisic; Hyoungshin Park; Christopher Cannizzaro; Jan Boublik; Robert Langer; Gordana Vunjak-Novakovic
Biophysical regulation during cardiac development and application to tissue engineering.
The International journal of developmental biology 2006;50(2-3):233-43.
2006: Jason A Burdick; Matthew Ward; Ellen Liang; Michael J Young; Robert Langer
Stimulation of neurite outgrowth by neurotrophins delivered from degradable hydrogels.
Biomaterials 2006;27(3):452-9.
2005: Ali Khademhosseini; Judy Yeh; George Eng; Jeffrey Karp; Hirokazu Kaji; Jeffrey Borenstein; Omid C Farokhzad; Robert Langer
Cell docking inside microwells within reversibly sealed microfluidic channels for fabricating multiphenotype cell arrays.
Lab on a chip 2005;5(12):1380-6.
2005: Molly M Stevens; Michael Mayer; Daniel G Anderson; Douglas B Weibel; George M Whitesides; Robert Langer
Direct patterning of mammalian cells onto porous tissue engineering substrates using agarose stamps.
Biomaterials 2005;26(36):7636-41.
2005: Blaine A Pfeifer; Jason A Burdick; Steve R Little; Robert Langer
Poly(ester-anhydride):poly(beta-amino ester) micro- and nanospheres: DNA encapsulation and cellular transfection.
International journal of pharmaceutics 2005;304(1-2):210-9.
2005: Minoru Tomita; Erin Lavik; Henry Klassen; Tasneem Zahir; Robert Langer; Michael J Young
Biodegradable polymer composite grafts promote the survival and differentiation of retinal progenitor cells.
Stem cells (Dayton, Ohio) 2005;23(10):1579-88.
2005: Lorenz Meinel; Robert Fajardo; Sandra Hofmann; Robert Langer; Jake Chen; Brian Snyder; Gordana Vunjak-Novakovic; David Kaplan
Silk implants for the healing of critical size bone defects.
Bone 2005;37(5):688-98.
2005: Kris C Wood; Steven R Little; Robert Langer; Paula T Hammond
A family of hierarchically self-assembling linear-dendritic hybrid polymers for highly efficient targeted gene delivery.
Angewandte Chemie (International ed. in English) 2005;44(41):6704-8.
2005: Steven R Little; David M Lynn; Sidharth V Puram; Robert Langer
Formulation and characterization of poly (beta amino ester) microparticles for genetic vaccine delivery.
Journal of controlled release : official journal of the Controlled Release Society 2005;107(3):449-62.
2005: Karin Warfvinge; Jens Folke Kiilgaard; Erin Lavik; Erik Scherfig; Robert Langer; Henry Klassen; Michael J Young
Retinal progenitor cell xenografts to the pig retina: morphologic integration and cytochemical differentiation.
Archives of ophthalmology 2005;123(10):1385-93.
2005: Yoon Yeo; Evangelia Bellas; William Firestone; Robert Langer; Daniel S Kohane
Complex coacervates for thermally sensitive controlled release of flavor compounds.
Journal of agricultural and food chemistry 2005;53(19):7518-25.
2005: Omid C Farokhzad; Ali Khademhosseini; Sangyong Jon; Aurelia Hermmann; Jianjun Cheng; Curtis Chin; Alice Kiselyuk; Benjamin A Teply; George Eng; Robert Langer
Microfluidic system for studying the interaction of nanoparticles and microparticles with cells.
Analytical chemistry 2005;77(17):5453-9.
2005: Yawen Li; Hong Linh Ho Duc; Betty M. Tyler; Tiffany Williams; Malinda Tupper; Robert Langer; Henry Brem; Michael J Cima
In vivo delivery of BCNU from a MEMS device to a tumor model.
Journal of controlled release : official journal of the Controlled Release Society 2005;106(1-2):138-45.
2005: Molly M Stevens; Robert P Marini; Dirk Schaefer; Joshua Aronson; Robert Langer; V Prasad Shastri
In vivo engineering of organs: the bone bioreactor.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(32):11450-5.
2005: Daniel G Anderson; David Putnam; Erin Lavik; Tahir A Mahmood; Robert Langer
Biomaterial microarrays: rapid, microscale screening of polymer-cell interaction.
Biomaterials 2005;26(23):4892-7.
2005: Shulamit Levenberg; Jeroen Rouwkema; Mara Macdonald; Evan Garfein; Daniel S Kohane; Diane C Darland; Robert Marini; Clemens A van Blitterswijk; Richard C Mulligan; Patricia A D'Amore; Robert Langer
Engineering vascularized skeletal muscle tissue.
Nature biotechnology 2005;23(7):879-84.
2005: Mariah S Hahn; James B Kobler; Steven M Zeitels; Robert Langer
Midmembranous vocal fold lamina propria proteoglycans across selected species.
The Annals of otology, rhinology, and laryngology 2005;114(6):451-62.
2005: Paul M George; Alvin W Lyckman; David A LaVan; Anita Hegde; Yuika Leung; Rupali Avasare; Chris Testa; Phillip M Alexander; Robert Langer; Mriganka Sur
Fabrication and biocompatibility of polypyrrole implants suitable for neural prosthetics.
Biomaterials 2005;26(17):3511-9.
2005: Erin Lavik; Henry Klassen; Karin Warfvinge; Robert Langer; Michael J Young
Fabrication of degradable polymer scaffolds to direct the integration and differentiation of retinal progenitors.
Biomaterials 2005;26(16):3187-96.
2005: Amy C Richards Grayson; Michael J Cima; Robert Langer
Size and temperature effects on poly(lactic-co-glycolic acid) degradation and microreservoir device performance.
Biomaterials 2005;26(14):2137-45.
2005: Akin Akinc; Mini Thomas; Alexander M Klibanov; Robert Langer
Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis.
The journal of gene medicine 2005;7(5):657-63.
2005: Philip Lee; Robert Langer; V Prasad Shastri
Role of n-methyl pyrrolidone in the enhancement of aqueous phase transdermal transport.
Journal of pharmaceutical sciences 2005;94(4):912-7.
2005: Shulamit Levenberg; Jason A Burdick; Thomas Kraehenbuehl; Robert Langer
Neurotrophin-induced differentiation of human embryonic stem cells on three-dimensional polymeric scaffolds.
Tissue engineering 2005;11(3-4):506-12.
2005: Daniel G Anderson; Akin Akinc; Naushad Hossain; Robert Langer
Structure/property studies of polymeric gene delivery using a library of poly(beta-amino esters).
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(3):426-34.
2005: Milica Radisic; William Deen; Robert Langer; Gordana Vunjak-Novakovic
Mathematical model of oxygen distribution in engineered cardiac tissue with parallel channel array perfused with culture medium containing oxygen carriers.
American journal of physiology. Heart and circulatory physiology 2005;288(3):H1278-89.
2005: Kahp Y Suh; Jen Ming Yang; Ali Khademhosseini; David Berry; Thanh-Nga T Tran; Hyongshin Park; Robert Langer
Characterization of chemisorbed hyaluronic acid directly immobilized on solid substrates.
Journal of biomedical materials research. Part B, Applied biomaterials 2005;72(2):292-8.
2005: David A LaVan; Robert F Padera; Thomas A Friedmann; John P Sullivan; Robert Langer; Daniel S Kohane
In vivo evaluation of tetrahedral amorphous carbon.
Biomaterials 2005;26(5):465-73.
2005: Steven R Little; Robert Langer
Nonviral delivery of cancer genetic vaccines.
Advances in biochemical engineering/biotechnology 2005;99():93-118.
2005: Christina Fidkowski; Mohammad MR Kaazempur-Mofrad; Jeffrey Borenstein; Joseph P Vacanti; Robert Langer; Yadong Wang
Endothelialized microvasculature based on a biodegradable elastomer.
Tissue engineering 2005;11(1-2):302-9.
2005: Jason A Burdick; Cindy Chung; Xinqiao Jia; Mark A Randolph; Robert Langer
Controlled degradation and mechanical behavior of photopolymerized hyaluronic acid networks.
Biomacromolecules 2005;6(1):386-91.
2005: Lorenz Meinel; Sandra Hofmann; Vassilis Karageorgiou; Carl A Kirker-Head; John McCool; Gloria A Gronowicz; Ludwig Zichner; Robert Langer; Gordana Vunjak-Novakovic; David L Kaplan
The inflammatory responses to silk films in vitro and in vivo.
Biomaterials 2005;26(2):147-55.
2005: Blaine A Pfeifer; Jason A Burdick; Robert Langer
Formulation and surface modification of poly(ester-anhydride) micro- and nanospheres.
Biomaterials 2005;26(2):117-24.
2004: Milica Radisic; Hyoungshin Park; Helen Shing; Thomas Consi; Frederick J Schoen; Robert Langer; Lisa E Freed; Gordana Vunjak-Novakovic
Functional assembly of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(52):18129-34.
2004: Rebecca S Shawgo; Gabriela Voskerician; Hong Linh Ho Duc; Yawen Li; Aaron Lynn; Matthew MacEwan; Robert Langer; James M Anderson; Michael J Cima
Repeated in vivo electrochemical activation and the biological effects of microelectromechanical systems drug delivery device.
Journal of biomedical materials research. Part A 2004;71(4):559-68.
2004: Yawen Li; Rebecca S Shawgo; Betty M. Tyler; Paul Henderson; John S Vogel; Aron Rosenberg; Phillip B Storm; Robert Langer; Henry Brem; Michael J Cima
In vivo release from a drug delivery MEMS device.
Journal of controlled release : official journal of the Controlled Release Society 2004;100(2):211-9.
2004: Daniel G Anderson; Weidan Peng; Akin Akinc; Naushad Hossain; Anat Kohn; Robert F Padera; Robert Langer; Janet A Sawicki
A polymer library approach to suicide gene therapy for cancer.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(45):16028-33.
2004: Lorenz Meinel; Sandra Hofmann; Vassilis Karageorgiou; Ludwig Zichner; Robert Langer; David Kaplan; Gordana Vunjak-Novakovic
Engineering cartilage-like tissue using human mesenchymal stem cells and silk protein scaffolds.
Biotechnology and bioengineering 2004;88(3):379-91.
2004: Omid C Farokhzad; Sangyong Jon; Ali Khademhosseini; Thanh-Nga T Tran; David A Lavan; Robert Langer
Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells.
Cancer research 2004;64(21):7668-72.
2004: Joseph Kushner; Daniel Blankschtein; Robert Langer
Experimental demonstration of the existence of highly permeable localized transport regions in low-frequency sonophoresis.
Journal of pharmaceutical sciences 2004;93(11):2733-45.
2004: Ali Khademhosseini; Judy Yeh; Sangyong Jon; George Eng; Kahp Y Suh; Jason A Burdick; Robert Langer
Molded polyethylene glycol microstructures for capturing cells within microfluidic channels.
Lab on a chip 2004;4(5):425-30.
2004: Lorenz Meinel; Vassilis Karageorgiou; Sandra Hofmann; Robert Fajardo; Brian Snyder; Chunmei Li; Ludwig Zichner; Robert Langer; Gordana Vunjak-Novakovic; David L Kaplan
Engineering bone-like tissue in vitro using human bone marrow stem cells and silk scaffolds.
Journal of biomedical materials research. Part A 2004;71(1):25-34.
2004: Daniel G Anderson; Jason A Burdick; Robert Langer
Materials science. Smart biomaterials.
Science (New York, N.Y.) 2004;305(5692):1923-4.
2004: Kahp Y Suh; Ali Khademhosseini; Pil J Yoo; Robert Langer
Patterning and separating infected bacteria using host-parasite and virus-antibody interactions.
Biomedical microdevices 2004;6(3):223-9.
2004: Molly M Stevens; Robert P Marini; Ivan Martin; Robert Langer; V Prasad Shastri
FGF-2 enhances TGF-beta1-induced periosteal chondrogenesis.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2004;22(5):1114-9.
2004: W Nicholas Haining; Daniel G Anderson; Steven R Little; Michael S von Bergwelt-Baildon; Angelo A Cardoso; Pedro Alves; Kostas Kosmatopoulos; Lee M Nadler; Robert Langer; Daniel S Kohane; Michael S von Berwelt-Baildon
pH-triggered microparticles for peptide vaccination.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(4):2578-85.
2004: Xinqiao Jia; Gaia Colombo; Robert F Padera; Robert Langer; Daniel S Kohane
Prolongation of sciatic nerve blockade by in situ cross-linked hyaluronic acid.
Biomaterials 2004;25(19):4797-804.
2004: Ali Khademhosseini; Kahp Y Suh; Jen M Yang; George Eng; Judy Yeh; Shulamit Levenberg; Robert Langer
Layer-by-layer deposition of hyaluronic acid and poly-L-lysine for patterned cell co-cultures.
Biomaterials 2004;25(17):3583-92.
2004: Kahp Y Suh; Ali Khademhosseini; George Eng; Robert Langer
Single nanocrystal arrays on patterned poly(ethylene glycol) copolymer microstructures using selective wetting and drying.
Langmuir : the ACS journal of surfaces and colloids 2004;20(15):6080-4.
2004: Robert P Marini; Molly M Stevens; Robert Langer; V Prasad Shastri
Hydraulic elevation of the periosteum: a novel technique for periosteal harvest.
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2004;17(4):229-33.
2004: Ying Chau; Frederick E Tan; Robert Langer
Synthesis and characterization of dextran-peptide-methotrexate conjugates for tumor targeting via mediation by matrix metalloproteinase II and matrix metalloproteinase IX.
Bioconjugate chemistry 2004;15(4):931-41.
2004: Ali Khademhosseini; Kahp Y Suh; Sangyong Jon; George Eng; Judy Yeh; Guan-Jong Chen; Robert Langer
A soft lithographic approach to fabricate patterned microfluidic channels.
Analytical chemistry 2004;76(13):3675-81.
2004: Erin Lavik; Robert Langer
Tissue engineering: current state and perspectives.
Applied microbiology and biotechnology 2004;65(1):1-8.
2004: Daniel G Anderson; Shulamit Levenberg; Robert Langer
Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells.
Nature biotechnology 2004;22(7):863-6.
2004: Yiwei Qi; Ganlin Zhao; Dongfang Liu; Zachary Shriver; Mallik Sundaram; shiladitya sengupta; Ganesh Venkataraman; Robert Langer; Ram Sasisekharan
Delivery of therapeutic levels of heparin and low-molecular-weight heparin through a pulmonary route.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(26):9867-72.
2004: Steven R Little; David M Lynn; Qing Ge; Daniel G Anderson; Sidharth V Puram; Jianzhu Chen; Herman N Eisen; Robert Langer
Poly-beta amino ester-containing microparticles enhance the activity of nonviral genetic vaccines.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(26):9534-9.
2004: Amy C Richards Grayson; Michael J Cima; Robert Langer
Molecular release from a polymeric microreservoir device: Influence of chemistry, polymer swelling, and loading on device performance.
Journal of biomedical materials research. Part A 2004;69(3):502-12.
2004: David Berry; David M Lynn; Ram Sasisekharan; Robert Langer
Poly(beta-amino ester)s promote cellular uptake of heparin and cancer cell death.
Chemistry & biology 2004;11(4):487-98.
2004: Gabriela Voskerician; Rebecca S Shawgo; P Anne Hiltner; James M Anderson; Michael J Cima; Robert Langer
In vivo inflammatory and wound healing effects of gold electrode voltammetry for MEMS micro-reservoir drug delivery device.
IEEE transactions on bio-medical engineering 2004;51(4):627-35.
2004: Robert Langer; David A Tirrell
Designing materials for biology and medicine.
Nature 2004;428(6982):487-92.
2004: Chun Wang; Qing Ge; David Ting; David Nguyen; Hui-Rong Shen; Jianzhu Chen; Herman N Eisen; Jorge Heller; Robert Langer; David Putnam
Molecularly engineered poly(ortho ester) microspheres for enhanced delivery of DNA vaccines.
Nature materials 2004;3(3):190-6.
2004: Mark R Prausnitz; Samir Mitragotri; Robert Langer
Current status and future potential of transdermal drug delivery.
Nature reviews. Drug discovery 2004;3(2):115-24.
2004: Molly M Stevens; Hala F Qanadilo; Robert Langer; V Prasad Shastri
A rapid-curing alginate gel system: utility in periosteum-derived cartilage tissue engineering.
Biomaterials 2004;25(5):887-94.
2004: V Prasad Shastri; Robert F Padera; Peter Tarcha; Robert Langer
A preliminary report on the biocompatibility of photopolymerizable semi-interpenetrating anhydride networks.
Biomaterials 2004;25(4):715-21.
2004: Kahp Y Suh; Jiehyun Seong; Ali Khademhosseini; Paul E Laibinis; Robert Langer
A simple soft lithographic route to fabrication of poly(ethylene glycol) microstructures for protein and cell patterning.
Biomaterials 2004;25(3):557-63.
2004: Milica Radisic; Liming Yang; Jan Boublik; Richard J Cohen; Robert Langer; Lisa E Freed; Gordana Vunjak-Novakovic
Medium perfusion enables engineering of compact and contractile cardiac tissue.
American journal of physiology. Heart and circulatory physiology 2004;286(2):H507-16.
2004: Amy C Richards Grayson; Gabriela Voskerician; Aaron Lynn; James M Anderson; Michael J Cima; Robert Langer
Differential degradation rates in vivo and in vitro of biocompatible poly(lactic acid) and poly(glycolic acid) homo- and co-polymers for a polymeric drug-delivery microchip.
Journal of biomaterials science. Polymer edition 2004;15(10):1281-304.
2004: Shulamit Levenberg; Robert Langer
Advances in tissue engineering.
Current topics in developmental biology 2004;61():113-34.
2004: J O Seidel; Ming Pei; Martha Gray; Robert Langer; Lisa E Freed; Gordana Vunjak-Novakovic
Long-term culture of tissue engineered cartilage in a perfused chamber with mechanical stimulation.
Biorheology 2004;41(3-4):445-58.
2004: Roxane Pouliot; Rosa Azhari; Hala F Qanadilo; Tahir A Mahmood; Michael S Triantafyllou; Robert Langer
Tissue engineering of fish skin: behavior of fish cells on poly(ethylene glycol terephthalate)/poly(butylene terephthalate) copolymers in relation to the composition of the polymer substrate as an initial step in constructing a robotic/living tissue hybrid.
Tissue engineering 2004;10(1-2):7-21.
2004: Lorenz Meinel; Vassilis Karageorgiou; Robert Fajardo; Brian Snyder; Vivek Shinde-Patil; Ludwig Zichner; David Kaplan; Robert Langer; Gordana Vunjak-Novakovic
Bone tissue engineering using human mesenchymal stem cells: effects of scaffold material and medium flow.
Annals of biomedical engineering 2004;32(1):112-22.
2003: Betty Yu; Ki Hean Kim; Peter So; Daniel Blankschtein; Robert Langer
Evaluation of fluorescent probe surface intensities as an indicator of transdermal permeant distributions using wide-area two-photon fluorescence microscopy.
Journal of pharmaceutical sciences 2003;92(12):2354-65.
2003: Amy C Richards Grayson; Insung S Choi; Betty M. Tyler; Paul P Wang; Henry Brem; Michael J Cima; Robert Langer
Multi-pulse drug delivery from a resorbable polymeric microchip device.
Nature materials 2003;2(11):767-72.
2003: Sangyong Jon; Daniel G Anderson; Robert Langer
Degradable poly(amino alcohol esters) as potential DNA vectors with low cytotoxicity.
Biomacromolecules 2003;4(6):1759-62.
2003: David Putnam; Alexander N Zelikin; Vladimir A Izumrudov; Robert Langer
Polyhistidine-PEG:DNA nanocomposites for gene delivery.
Biomaterials 2003;24(24):4425-33.
2003: Shulamit Levenberg; Ngan F Huang; Erin Lavik; Arlin Rogers; Joseph Itskovitz-Eldor; Robert Langer
Differentiation of human embryonic stem cells on three-dimensional polymer scaffolds.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(22):12741-6.
2003: Daniel S Kohane; Daniel G Anderson; Christine Yu; Robert Langer
pH-triggered release of macromolecules from spray-dried polymethacrylate microparticles.
Pharmaceutical research 2003;20(10):1533-8.
2003: David A LaVan; Terry McGuire; Robert Langer
Small-scale systems for in vivo drug delivery.
Nature biotechnology 2003;21(10):1184-91.
2003: Akin Akinc; Daniel G Anderson; David M Lynn; Robert Langer
Synthesis of poly(beta-amino ester)s optimized for highly effective gene delivery.
Bioconjugate chemistry 2003;14(5):979-88.
2003: V Prasad Shastri; Patrice Hildgen; Robert Langer
In situ pore formation in a polymer matrix by differential polymer degradation.
Biomaterials 2003;24(18):3133-7.
2003: Karen Fu; Roy Harrell; Kim Zinski; Christina Um; Ana Jaklenec; Jan Frazier; Noah Lotan; Paul Burke; Alexander M Klibanov; Robert Langer
A potential approach for decreasing the burst effect of protein from PLGA microspheres.
Journal of pharmaceutical sciences 2003;92(8):1582-91.
2003: Daniel G Anderson; David M Lynn; Robert Langer
Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery.
Angewandte Chemie (International ed. in English) 2003;42(27):3153-8.
2003: Daniel S Kohane; Sarah E Smith; David N Louis; Gaia Colombo; Peter Ghoroghchian; Nicole G M Hunfeld; Charles B Berde; Robert Langer
Prolonged duration local anesthesia from tetrodotoxin-enhanced local anesthetic microspheres.
Pain 2003;104(1-2):415-21.
2003: Yadong Wang; Yu Mi Kim; Robert Langer
In vivo degradation characteristics of poly(glycerol sebacate).
Journal of biomedical materials research. Part A 2003;66(1):192-7.
2003: Amir H Nashat; Robert Langer
Temporal characteristics of activation, deactivation, and restimulation of signal transduction following depolarization in the pheochromocytoma cell line PC12.
Molecular and cellular biology 2003;23(14):4788-95.
2003: Biancamaria Baroli; V Prasad Shastri; Robert Langer
A method to protect sensitive molecules from a light-induced polymerizing environment.
Journal of pharmaceutical sciences 2003;92(6):1186-95.
2003: Milica Radisic; Michelle Euloth; Liming Yang; Robert Langer; Lisa E Freed; Gordana Vunjak-Novakovic
High-density seeding of myocyte cells for cardiac tissue engineering.
Biotechnology and bioengineering 2003;82(4):403-14.
2003: Akin Akinc; David M Lynn; Daniel G Anderson; Robert Langer
Parallel synthesis and biophysical characterization of a degradable polymer library for gene delivery.
Journal of the American Chemical Society 2003;125(18):5316-23.
2003: Joerg Lahann; Mercedes Balcells; Hang Lu; Teresa Rodon; Klavs F Jensen; Robert Langer
Reactive polymer coatings: a first step toward surface engineering of microfluidic devices.
Analytical chemistry 2003;75(9):2117-22.
2003: Gabriela Voskerician; Matthew S Shive; Rebecca S Shawgo; Horst von Recum; James M Anderson; Michael J Cima; Robert Langer
Biocompatibility and biofouling of MEMS drug delivery devices.
Biomaterials 2003;24(11):1959-67.
2003: David A LaVan; Paul M George; Robert Langer
Simple, three-dimensional microfabrication of electrodeposited structures.
Angewandte Chemie (International ed. in English) 2003;42(11):1262-5.
2003: Betty Yu; Ki Hean Kim; Peter So; Daniel Blankschtein; Robert Langer
Visualization of oleic acid-induced transdermal diffusion pathways using two-photon fluorescence microscopy.
The Journal of investigative dermatology 2003;120(3):448-55.
2003: Philip Lee; Robert Langer; V Prasad Shastri
Novel microemulsion enhancer formulation for simultaneous transdermal delivery of hydrophilic and hydrophobic drugs.
Pharmaceutical research 2003;20(2):264-9.
2003: Mallik Sundaram; Yiwei Qi; Zachary Shriver; Dongfang Liu; Ganlin Zhao; Ganesh Venkataraman; Robert Langer; Ram Sasisekharan
Rational design of low-molecular weight heparins with improved in vivo activity.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(2):651-6.
2003: Joerg Lahann; Samir Mitragotri; Thanh-Nga Tran; Hiroki Kaido; Jagannathan Sundaram; Insung S Choi; Saskia Hoffer; Gabor A Somorjai; Robert Langer
A reversibly switching surface.
Science (New York, N.Y.) 2003;299(5605):371-4.
2003: André X C N Valente; Robert Langer; Howard A Stone; David A Edwards
Recent advances in the development of an inhaled insulin product.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2003;17(1):9-17.
2002: Henning Madry; Robert F Padera; Joachim Seidel; Robert Langer; Lisa E Freed; Stephen B Trippel; Gordana Vunjak-Novakovic
Gene transfer of a human insulin-like growth factor I cDNA enhances tissue engineering of cartilage.
Human gene therapy 2002;13(13):1621-30.
2002: Daniel S Kohane; Nikolaus Plesnila; Sunu S Thomas; Dean Le; Robert Langer; Michael A Moskowitz
Lipid-sugar particles for intracranial drug delivery: safety and biocompatibility.
Brain research 2002;946(2):206-13.
2002: Maria A Rupnick; Dipak Panigrahy; Chen-Yu zhang; Susan M Dallabrida; Bradford B Lowell; Robert Langer; M Judah Folkman
Adipose tissue mass can be regulated through the vasculature.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10730-5.
2002: Hua Tang; Chiao Chun Joanne Wang; Daniel Blankschtein; Robert Langer
An investigation of the role of cavitation in low-frequency ultrasound-mediated transdermal drug transport.
Pharmaceutical research 2002;19(8):1160-9.
2002: Hua Tang; Daniel Blankschtein; Robert Langer
Prediction of steady-state skin permeabilities of polar and nonpolar permeants across excised pig skin based on measurements of transient diffusion: characterization of hydration effects on the skin porous pathway.
Journal of pharmaceutical sciences 2002;91(8):1891-907.
2002: Hua Tang; Daniel Blankschtein; Robert Langer
Effects of low-frequency ultrasound on the transdermal permeation of mannitol: comparative studies with in vivo and in vitro skin.
Journal of pharmaceutical sciences 2002;91(8):1776-94.
2002: Rebecca L Carrier; Maria A Rupnick; Robert Langer; Frederick J Schoen; Lisa E Freed; Gordana Vunjak-Novakovic
Effects of oxygen on engineered cardiac muscle.
Biotechnology and bioengineering 2002;78(6):617-25.
2002: Akin Akinc; Robert Langer
Measuring the pH environment of DNA delivered using nonviral vectors: implications for lysosomal trafficking.
Biotechnology and bioengineering 2002;78(5):503-8.
2002: Betty Yu; Ki Hean Kim; Peter So; Daniel Blankschtein; Robert Langer
Topographic heterogeneity in transdermal transport revealed by high-speed two-photon microscopy: determination of representative skin sample sizes.
The Journal of investigative dermatology 2002;118(6):1085-8.
2002: Yadong Wang; Guillermo A Ameer; Barbara J Sheppard; Robert Langer
A tough biodegradable elastomer.
Nature biotechnology 2002;20(6):602-6.
2002: Alexander N Zelikin; David Putnam; Prasad Shastri; Robert Langer; Vladimir A Izumrudov
Aliphatic ionenes as gene delivery agents: elucidation of structure-function relationship through modification of charge density and polymer length.
Bioconjugate chemistry 2002;13(3):548-53.
2002: Shulamit Levenberg; Justin S Golub; Michal Amit; Joseph Itskovitz-Eldor; Robert Langer
Endothelial cells derived from human embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4391-6.
2002: Rebecca L Carrier; Maria A Rupnick; Robert Langer; Frederick J Schoen; Lisa E Freed; Gordana Vunjak-Novakovic
Perfusion improves tissue architecture of engineered cardiac muscle.
Tissue engineering 2002;8(2):175-88.
2002: Takaaki Terahara; Samir Mitragotri; Joseph Kost; Robert Langer
Dependence of low-frequency sonophoresis on ultrasound parameters; distance of the horn and intensity.
International journal of pharmaceutics 2002;235(1-2):35-42.
2002: yang teng; Erin Lavik; Xianlu Qu; Kook In Park; Jitka Ourednik; David Zurakowski; Robert Langer; Evan Y Snyder
Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3024-9.
2002: Daniel S Kohane; Michael Lipp; Ramsey C Kinney; Douglas C Anthony; David N Louis; Noah Lotan; Robert Langer
Biocompatibility of lipid-protein-sugar particles containing bupivacaine in the epineurium.
Journal of biomedical materials research 2002;59(3):450-9.
2002: Takaaki Terahara; Samir Mitragotri; Robert Langer
Porous resins as a cavitation enhancer for low-frequency sonophoresis.
Journal of pharmaceutical sciences 2002;91(3):753-9.
2002: Torsten Blunk; Alisha L Sieminski; Keith J Gooch; Donald L Courter; Anthony P Hollander; A Menahem Nahir; Robert Langer; Gordana Vunjak-Novakovic; Lisa E Freed
Differential effects of growth factors on tissue-engineered cartilage.
Tissue engineering 2002;8(1):73-84.
2002: Alexander N Zelikin; David M Lynn; jian farhadi; Ivan Martin; Venkatram Shastri; Robert Langer
Erodible conducting polymers for potential biomedical applications.
Angewandte Chemie (International ed. in English) 2002;41(1):141-4.
2002: David A LaVan; David M Lynn; Robert Langer
Moving smaller in drug discovery and delivery.
Nature reviews. Drug discovery 2002;1(1):77-84.
2002: Erin Lavik; yang teng; Evan Snyder; Robert Langer
Seeding neural stem cells on scaffolds of PGA, PLA, and their copolymers.
Methods in molecular biology (Clifton, N.J.) 2002;198():89-97.
2002: Guillermo A Ameer; T A Mahmood; Robert Langer
A biodegradable composite scaffold for cell transplantation.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2002;20(1):16-9.
2001: Jennifer H Elisseeff; W McIntosh; Karen Fu; B T Blunk; Robert Langer
Controlled-release of IGF-I and TGF-beta1 in a photopolymerizing hydrogel for cartilage tissue engineering.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2001;19(6):1098-104.
2001: W S Choi; G G Murthy; David A Edwards; Robert Langer; Alexander M Klibanov
Inhalation delivery of proteins from ethanol suspensions.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11103-7.
2001: Guillermo A Ameer; E T Crumpler; Robert Langer
Cell-killing potential of a water-soluble radical initiator.
International journal of cancer. Journal international du cancer 2001;93(6):875-9.
2001: David M Lynn; Daniel G Anderson; David Putnam; Robert Langer
Accelerated discovery of synthetic transfection vectors: parallel synthesis and screening of a degradable polymer library.
Journal of the American Chemical Society 2001;123(33):8155-6.
2001: C Perez; A Sanchez; David Putnam; David Ting; Robert Langer; María José Alonso
Poly(lactic acid)-poly(ethylene glycol) nanoparticles as new carriers for the delivery of plasmid DNA.
Journal of controlled release : official journal of the Controlled Release Society 2001;75(1-2):211-24.
2001: Robert Langer
Drug delivery. Drugs on target.
Science (New York, N.Y.) 2001;293(5527):58-9.
2001: Betty Yu; Chen-Yuan Dong; Peter So; Daniel Blankschtein; Robert Langer
In vitro visualization and quantification of oleic acid induced changes in transdermal transport using two-photon fluorescence microscopy.
The Journal of investigative dermatology 2001;117(1):16-25.
2001: Erin Lavik; JS Hrkach; N Lotan; R Nazarov; Robert Langer
A simple synthetic route to the formation of a block copolymer of poly(lactic-co-glycolic acid) and polylysine for the fabrication of functionalized, degradable structures for biomedical applications.
Journal of biomedical materials research 2001;58(3):291-4.
2001: Hua Tang; Samir Mitragotri; Daniel Blankschtein; Robert Langer
Theoretical description of transdermal transport of hydrophilic permeants: application to low-frequency sonophoresis.
Journal of pharmaceutical sciences 2001;90(5):545-68.
2001: Ivan Martin; V Prasad Shastri; Robert F Padera; J Yang; A J Mackay; Robert Langer; Gordana Vunjak-Novakovic; Lisa E Freed
Selective differentiation of mammalian bone marrow stromal cells cultured on three-dimensional polymer foams.
Journal of biomedical materials research 2001;55(2):229-35.
2001: Guillermo A Ameer; E A Grovender; Hidde L Ploegh; David Ting; W F Owen; Maria A Rupnick; Robert Langer
A novel immunoadsorption device for removing beta2-microglobulin from whole blood.
Kidney international 2001;59(4):1544-50.
2001: David Putnam; C A Gentry; Daniel W Pack; Robert Langer
Polymer-based gene delivery with low cytotoxicity by a unique balance of side-chain termini.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(3):1200-5.
2001: S Hirosue; B G Müller; R C Mulligan; Robert Langer
Plasmid DNA encapsulation and release from solvent diffusion nanospheres.
Journal of controlled release : official journal of the Controlled Release Society 2001;70(1-2):231-42.
2001: Maria Papadaki; Nenad Bursac; Robert Langer; Joshua R Merok; Gordana Vunjak-Novakovic; Lisa E Freed
Tissue engineering of functional cardiac muscle: molecular, structural, and electrophysiological studies.
American journal of physiology. Heart and circulatory physiology 2001;280(1):H168-78.
2001: Maria Papadaki; T Mahmood; Pavan K Gupta; Menno B Claase; Dirk W Grijpma; Jens Riesle; Clemens A van Blitterswijk; Robert Langer
The different behaviors of skeletal muscle cells and chondrocytes on PEGT/PBT block copolymers are related to the surface properties of the substrate.
Journal of biomedical materials research 2001;54(1):47-58.
2000: Dirk Schaefer; Ivan Martin; P Shastri; Robert F Padera; Robert Langer; Lisa E Freed; Gordana Vunjak-Novakovic
In vitro generation of osteochondral composites.
Biomaterials 2000;21(24):2599-606.
2000: Daniel S Kohane; M Lipp; R C Kinney; N Lotan; Robert Langer
Sciatic nerve blockade with lipid-protein-sugar particles containing bupivacaine.
Pharmaceutical research 2000;17(10):1243-9.
2000: Samir Mitragotri; M Coleman; Joseph Kost; Robert Langer
Analysis of ultrasonically extracted interstitial fluid as a predictor of blood glucose levels.
Journal of applied physiology (Bethesda, Md. : 1985) 2000;89(3):961-6.
2000: Jennifer H Elisseeff; W McIntosh; K Anseth; S Riley; PM Ragan; Robert Langer
Photoencapsulation of chondrocytes in poly(ethylene oxide)-based semi-interpenetrating networks.
Journal of biomedical materials research 2000;51(2):164-71.
2000: Samir Mitragotri; D Ray; J Farrell; H Tang; B Yu; Joseph Kost; Daniel Blankschtein; Robert Langer
Synergistic effect of low-frequency ultrasound and sodium lauryl sulfate on transdermal transport.
Journal of pharmaceutical sciences 2000;89(7):892-900.
2000: Samir Mitragotri; M Coleman; Joseph Kost; Robert Langer
Transdermal extraction of analytes using low-frequency ultrasound.
Pharmaceutical research 2000;17(4):466-70.
2000: V Prasad Shastri; Ivan Martin; Robert Langer
Macroporous polymer foams by hydrocarbon templating.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(5):1970-5.
2000: Robert Langer
Biomaterials in drug delivery and tissue engineering: one laboratory's experience.
Accounts of chemical research 2000;33(2):94-101.
2000: B S Kim; JS Hrkach; Robert Langer
Biodegradable photo-crosslinked poly(ether-ester) networks for lubricious coatings.
Biomaterials 2000;21(3):259-65.
2000: Daniel W Pack; David Putnam; Robert Langer
Design of imidazole-containing endosomolytic biopolymers for gene delivery.
Biotechnology and bioengineering 2000;67(2):217-23.
2000: Samir Mitragotri; J Farrell; Hua Tang; Takaaki Terahara; Joseph Kost; Robert Langer
Determination of threshold energy dose for ultrasound-induced transdermal drug transport.
Journal of controlled release : official journal of the Controlled Release Society 2000;63(1-2):41-52.
2000: Robert Langer
Tissue engineering.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;1(1):12-5.
2000: Ivan Martin; B Obradovic; S Treppo; Alan J Grodzinsky; Robert Langer; Lisa E Freed; Gordana Vunjak-Novakovic
Modulation of the mechanical properties of tissue engineered cartilage.
Biorheology 2000;37(1-2):141-7.
2000: N Patel; R Bhandari; Kevin M Shakesheff; SM Cannizzaro; Martyn C Davies; Robert Langer; Clive J Roberts; Saul J B Tendler; Philip M Williams
Printing patterns of biospecifically-adsorbed protein.
Journal of biomaterials science. Polymer edition 2000;11(3):319-31.
2000: Karen Fu; Daniel W Pack; Alexander M Klibanov; Robert Langer
Visual evidence of acidic environment within degrading poly(lactic-co-glycolic acid) (PLGA) microspheres.
Pharmaceutical research 2000;17(1):100-6.
1999: I Martin; Gordana Vunjak-Novakovic; J Yang; Robert Langer; L E Freed
Mammalian chondrocytes expanded in the presence of fibroblast growth factor 2 maintain the ability to differentiate and regenerate three-dimensional cartilaginous tissue.
Experimental cell research 1999;253(2):681-8.
1999: María Tobío; SP Schwendeman; Y Guo; J McIver; Robert Langer; María José Alonso
Improved immunogenicity of a core-coated tetanus toxoid delivery system.
Vaccine 1999;18(7-8):618-22.
1999: Rita Vanbever; J D Mintzes; J Wang; J Nice; D Chen; R Batycky; Robert Langer; David A Edwards
Formulation and physical characterization of large porous particles for inhalation.
Pharmaceutical research 1999;16(11):1735-42.
1999: thomas zewert; Uwe Pliquett; Rita Vanbever; Robert Langer; James C Weaver
Creation of transdermal pathways for macromolecule transport by skin electroporation and a low toxicity, pathway-enlarging molecule.
Bioelectrochemistry and bioenergetics (Lausanne, Switzerland) 1999;49(1):11-20.
1999: Rebecca L Carrier; Maria Papadaki; Maria A Rupnick; Frederick J Schoen; Nenad Bursac; Robert Langer; Lisa E Freed; Gordana Vunjak-Novakovic
Cardiac tissue engineering: cell seeding, cultivation parameters, and tissue construct characterization.
Biotechnology and bioengineering 1999;64(5):580-9.
1999: Jennifer H Elisseeff; K Anseth; D Sims; W McIntosh; M Randolph; Michael J Yaremchuk; Robert Langer
Transdermal photopolymerization of poly(ethylene oxide)-based injectable hydrogels for tissue-engineered cartilage.
Plastic and reconstructive surgery 1999;104(4):1014-22.
1999: Guillermo A Ameer; S Raghavan; Ram Sasisekharan; W Harmon; Charles Cooney; Robert Langer
Regional heparinization via simultaneous separation and reaction in a novel Taylor-Couette flow device.
Biotechnology and bioengineering 1999;63(5):618-24.
1999: Rubén D Sinisterra; V Prasad Shastri; R Najjar; Robert Langer
Encapsulation and release of rhodium(II) citrate and its association complex with hydroxypropyl-beta-cyclodextrin from biodegradable polymer microspheres.
Journal of pharmaceutical sciences 1999;88(5):574-6.
1999: Abdellaziz Ben-Jebria; D Chen; ML Eskew; Rita Vanbever; Robert Langer; David A Edwards
Large porous particles for sustained protection from carbachol-induced bronchoconstriction in guinea pigs.
Pharmaceutical research 1999;16(4):555-61.
1999: Robert Langer; Joseph P Vacanti
Tissue engineering: the challenges ahead.
Scientific American 1999;280(4):86-9.
1999: Jennifer H Elisseeff; K Anseth; D Sims; W McIntosh; M Randolph; Robert Langer
Transdermal photopolymerization for minimally invasive implantation.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3104-7.
1999: Guillermo A Ameer; W Harmon; Ram Sasisekharan; Robert Langer
Investigation of a whole blood fluidized bed Taylor-Couette flow device for enzymatic heparin neutralization.
Biotechnology and bioengineering 1999;62(5):602-8.
1999: Guillermo A Ameer; G Barabino; Ram Sasisekharan; W Harmon; Charles Cooney; Robert Langer
Ex vivo evaluation of a Taylor-Couette flow, immobilized heparinase I device for clinical application.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):2350-5.
1999: P X Ma; Robert Langer
Morphology and mechanical function of long-term in vitro engineered cartilage.
Journal of biomedical materials research 1999;44(2):217-21.
1999: T Chen; Robert Langer; James C Weaver
Charged microbeads are not transported across the human stratum corneum in vitro by short high-voltage pulses.
Bioelectrochemistry and bioenergetics (Lausanne, Switzerland) 1999;48(1):181-92.
1999: Kristi S Anseth; V R Shastri; Robert Langer
Photopolymerizable degradable polyanhydrides with osteocompatibility.
Nature biotechnology 1999;17(2):156-9.
1999: J T Santini; Michael J Cima; Robert Langer
A controlled-release microchip.
Nature 1999;397(6717):335-8.
1999: Gordana Vunjak-Novakovic; Ivan Martin; B Obradovic; S Treppo; Alan J Grodzinsky; Robert Langer; Lisa E Freed
Bioreactor cultivation conditions modulate the composition and mechanical properties of tissue-engineered cartilage.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1999;17(1):130-8.
1999: G Caponetti; JS Hrkach; B Kriwet; M Poh; N Lotan; P Colombo; Robert Langer
Microparticles of novel branched copolymers of lactic acid and amino acids: preparation and characterization.
Journal of pharmaceutical sciences 1999;88(1):136-41.
1999: S Ando; David Putnam; Daniel W Pack; Robert Langer
PLGA microspheres containing plasmid DNA: preservation of supercoiled DNA via cryopreparation and carbohydrate stabilization.
Journal of pharmaceutical sciences 1999;88(1):126-30.
1998: Jianchuan Gao; L Niklason; Robert Langer
Surface hydrolysis of poly(glycolic acid) meshes increases the seeding density of vascular smooth muscle cells.
Journal of biomedical materials research 1998;42(3):417-24.
1998: Jens Riesle; Anthony P Hollander; Robert Langer; Lisa E Freed; Gordana Vunjak-Novakovic
Collagen in tissue-engineered cartilage: types, structure, and crosslinks.
Journal of cellular biochemistry 1998;71(3):313-27.
1998: T Chen; E M Segall; Robert Langer; James C Weaver
Skin electroporation: rapid measurements of the transdermal voltage and flux of four fluorescent molecules show a transition to large fluxes near 50 V.
Journal of pharmaceutical sciences 1998;87(11):1368-74.
1998: N Patel; Robert F Padera; GH Sanders; SM Cannizzaro; Martyn C Davies; Robert Langer; Clive J Roberts; Saul J B Tendler; Philip M Williams; Kevin M Shakesheff
Spatially controlled cell engineering on biodegradable polymer surfaces.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(14):1447-54.
1998: T Chen; Robert Langer; James C Weaver
Skin electroporation causes molecular transport across the stratum corneum through localized transport regions.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 1998;3(2):159-65.
1998: David A Edwards; Abdellaziz Ben-Jebria; Robert Langer
Recent advances in pulmonary drug delivery using large, porous inhaled particles.
Journal of applied physiology (Bethesda, Md. : 1985) 1998;85(2):379-85.
1998: SM Cannizzaro; Robert F Padera; Robert Langer; R A Rogers; F E Black; Martyn C Davies; Saul J B Tendler; Kevin M Shakesheff
A novel biotinylated degradable polymer for cell-interactive applications.
Biotechnology and bioengineering 1998;58(5):529-35.
1998: SP Schwendeman; María Tobío; M Joworowicz; María José Alonso; Robert Langer
New strategies for the microencapsulation of tetanus vaccine.
Journal of microencapsulation 1998;15(3):299-318.
1998: Robert Langer
Drug delivery and targeting.
Nature 1998;392(6679 Suppl):5-10.
1998: L E Freed; Anthony P Hollander; I Martin; J R Barry; Robert Langer; Gordana Vunjak-Novakovic
Chondrogenesis in a cell-polymer-bioreactor system.
Experimental cell research 1998;240(1):58-65.
1998: Gordana Vunjak-Novakovic; B Obradovic; Ivan Martin; P M Bursac; Robert Langer; Lisa E Freed
Dynamic cell seeding of polymer scaffolds for cartilage tissue engineering.
Biotechnology progress 1998;14(2):193-202.
1998: H R Costantino; SP Schwendeman; Robert Langer; Alexander M Klibanov
Deterioration of lyophilized pharmaceutical proteins.
Biochemistry. Biokhimii͡a 1998;63(3):357-63.
1998: Carmen Evora; Isabel Soriano; R A Rogers; K N Shakesheff; Justin Hanes; Robert Langer
Relating the phagocytosis of microparticles by alveolar macrophages to surface chemistry: the effect of 1,2-dipalmitoylphosphatidylcholine.
Journal of controlled release : official journal of the Controlled Release Society 1998;51(2-3):143-52.
1998: María Tobío; Ruxandra Gref; A Sánchez; Robert Langer; María José Alonso
Stealth PLA-PEG nanoparticles as protein carriers for nasal administration.
Pharmaceutical research 1998;15(2):270-5.
1998: J Gao; L Niklason; X M Zhao; Robert Langer
Surface modification of polyanhydride microspheres.
Journal of pharmaceutical sciences 1998;87(2):246-8.
1998: Justin Hanes; M Chiba; Robert Langer
Degradation of porous poly(anhydride-co-imide) microspheres and implications for controlled macromolecule delivery.
Biomaterials 1998;19(1-3):163-72.
1997: Lisa E Freed; Robert Langer; Ivan Martin; N R Pellis; Gordana Vunjak-Novakovic
Tissue engineering of cartilage in space.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):13885-90.
1997: D J Mooney; K Sano; P M Kaufmann; K Majahod; B Schloo; Joseph P Vacanti; Robert Langer
Long-term engraftment of hepatocytes transplanted on biodegradable polymer sponges.
Journal of biomedical materials research 1997;37(3):413-20.
1997: R P Batycky; Justin Hanes; Robert Langer; David A Edwards
A theoretical model of erosion and macromolecular drug release from biodegrading microspheres.
Journal of pharmaceutical sciences 1997;86(12):1464-77.
1997: A D Cook; U B Pajvani; JS Hrkach; SM Cannizzaro; Robert Langer
Colorimetric analysis of surface reactive amino groups on poly(lactic acid-co-lysine):poly(lactic acid) blends.
Biomaterials 1997;18(21):1417-24.
1997: Samir Mitragotri; Daniel Blankschtein; Robert Langer
An explanation for the variation of the sonophoretic transdermal transport enhancement from drug to drug.
Journal of pharmaceutical sciences 1997;86(10):1190-2.
1997: M E Johnson; Daniel Blankschtein; Robert Langer
Evaluation of solute permeation through the stratum corneum: lateral bilayer diffusion as the primary transport mechanism.
Journal of pharmaceutical sciences 1997;86(10):1162-72.
1997: C E Schmidt; V R Shastri; Joseph P Vacanti; Robert Langer
Stimulation of neurite outgrowth using an electrically conducting polymer.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(17):8948-53.
1997: Robert Langer
Tissue engineering: a new field and its challenges.
Pharmaceutical research 1997;14(7):840-1.
1997: M Chiba; Justin Hanes; Robert Langer
Controlled protein delivery from biodegradable tyrosine-containing poly(anhydride-co-imide) microspheres.
Biomaterials 1997;18(13):893-901.
1997: David A Edwards; Justin Hanes; G Caponetti; JS Hrkach; Abdellaziz Ben-Jebria; ML Eskew; J Mintzes; DR Deaver; N Lotan; Robert Langer
Large porous particles for pulmonary drug delivery.
Science (New York, N.Y.) 1997;276(5320):1868-71.
1997: A D Cook; JS Hrkach; N N Gao; I M Johnson; U B Pajvani; SM Cannizzaro; Robert Langer
Characterization and development of RGD-peptide-modified poly(lactic acid-co-lysine) as an interactive, resorbable biomaterial.
Journal of biomedical materials research 1997;35(4):513-23.
1997: H Chen; Robert Langer
Magnetically-responsive polymerized liposomes as potential oral delivery vehicles.
Pharmaceutical research 1997;14(4):537-40.
1997: T H Kim; H M Lee; H Utsonomiya; P Ma; Robert Langer; Emmett V Schmidt; Joseph P Vacanti
Enhanced survival of transgenic hepatocytes expressing hepatocyte growth factor in hepatocyte tissue engineering.
Transplantation proceedings 1997;29(1-2):858-60.
1997: R Gref; Y Minamitake; M T Peracchia; A Domb; V Trubetskoy; V Torchilin; Robert Langer
Poly(ethylene glycol)-coated nanospheres: potential carriers for intravenous drug administration.
Pharmaceutical biotechnology 1997;10():167-98.
1997: JS Hrkach; M T Peracchia; A Domb; N Lotan; Robert Langer
Nanotechnology for biomaterials engineering: structural characterization of amphiphilic polymeric nanoparticles by 1H NMR spectroscopy.
Biomaterials 1997;18(1):27-30.
1996: Mark R Prausnitz; J A Gimm; R H Guy; Robert Langer; James C Weaver; C Cullander
Imaging regions of transport across human stratum corneum during high-voltage and low-voltage exposures.
Journal of pharmaceutical sciences 1996;85(12):1363-70.
1996: L R Brown; Elazer R Edelman; F Fischel-Ghodsian; Robert Langer
Characterization of glucose-mediated insulin release from implantable polymers.
Journal of pharmaceutical sciences 1996;85(12):1341-5.
1996: Henry R Costantino; S P Schwendeman; Kai Griebenow; Alexander M Klibanov; Robert Langer
The secondary structure and aggregation of lyophilized tetanus toxoid.
Journal of pharmaceutical sciences 1996;85(12):1290-3.
1996: Michael J Yaszemski; R G Payne; W C Hayes; Robert Langer; Antonios G Mikos
In vitro degradation of a poly(propylene fumarate)-based composite material.
Biomaterials 1996;17(22):2127-30.
1996: J Castillo; J Curley; J Hotz; M Uezono; J Tigner; M Chasin; R Wilder; Robert Langer; Charles B Berde
Glucocorticoids prolong rat sciatic nerve blockade in vivo from bupivacaine microspheres.
Anesthesiology 1996;85(5):1157-66.
1996: M E Johnson; David A Berk; Daniel Blankschtein; David E Golan; Rakesh K Jain; Robert Langer
Lateral diffusion of small compounds in human stratum corneum and model lipid bilayer systems.
Biophysical journal 1996;71(5):2656-68.
1996: T Shinoka; Peter X Ma; D Shum-Tim; C K Breuer; Robert A Cusick; G Zund; Robert Langer; J P Vacanti; John E Mayer
Tissue-engineered heart valves. Autologous valve leaflet replacement study in a lamb model.
Circulation 1996;94(9 Suppl):II164-8.
1996: H Chen; V Torchilin; Robert Langer
Lectin-bearing polymerized liposomes as potential oral vaccine carriers.
Pharmaceutical research 1996;13(9):1378-83.
1996: D A Edwards; F Schneck; I Zhang; A M Davis; H Chen; Robert Langer
Spontaneous vesicle formation at lipid bilayer membranes.
Biophysical journal 1996;71(3):1208-14.
1996: R Godavarti; M Davis; Ganesh Venkataraman; C Cooney; Robert Langer; Ram Sasisekharan
Heparinase III from Flavobacterium heparinum: cloning and recombinant expression in Escherichia coli.
Biochemical and biophysical research communications 1996;225(3):751-8.
1996: D J Mooney; D F Baldwin; N P Suh; J P Vacanti; Robert Langer
Novel approach to fabricate porous sponges of poly(D,L-lactic-co-glycolic acid) without the use of organic solvents.
Biomaterials 1996;17(14):1417-22.
1996: M E Johnson; Samir Mitragotri; A Patel; Daniel Blankschtein; Robert Langer
Synergistic effects of chemical enhancers and therapeutic ultrasound on transdermal drug delivery.
Journal of pharmaceutical sciences 1996;85(7):670-9.
1996: A Sanchez; R K Gupta; María José Alonso; G R Siber; Robert Langer
Pulsed controlled-released system for potential use in vaccine delivery.
Journal of pharmaceutical sciences 1996;85(6):547-52.
1996: J Curley; J Castillo; J Hotz; M Uezono; S Hernandez; J O Lim; J Tigner; M Chasin; Robert Langer; Charles B Berde
Prolonged regional nerve blockade. Injectable biodegradable bupivacaine/polyester microspheres.
Anesthesiology 1996;84(6):1401-10.
1996: K Sano; Robert A Cusick; Hanmin Lee; Jörg-Matthias Pollok; Peter M Kaufmann; S Uyama; David Mooney; Robert Langer; J P Vacanti
Regenerative signals for heterotopic hepatocyte transplantation.
Transplantation proceedings 1996;28(3):1857-8.
1996: R Godavarti; C L Cooney; Robert Langer; Ram Sasisekharan
Heparinase I from Flavobacterium heparinum. Identification of a critical histidine residue essential for catalysis as probed by chemical modification and site-directed mutagenesis.
Biochemistry 1996;35(21):6846-52.
1996: Mohamed Attawia; Kathryn E Uhrich; E Botchwey; Robert Langer; Cato T Laurencin
In vitro bone biocompatibility of poly (anhydride-co-imides) containing pyromellitylimidoalanine.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1996;14(3):445-54.
1996: S Ernst; Ganesh Venkataraman; S Winkler; R Godavarti; Robert Langer; C L Cooney; Ram Sasisekharan
Expression in Escherichia coli, purification and characterization of heparinase I from Flavobacterium heparinum.
The Biochemical journal 1996;315 ( Pt 2)():589-97.
1996: D A Edwards; K J Gooch; I Zhang; G H McKinley; Robert Langer
The nucleation of receptor-mediated endocytosis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(5):1786-91.
1996: Samir Mitragotri; Daniel Blankschtein; Robert Langer
Transdermal drug delivery using low-frequency sonophoresis.
Pharmaceutical research 1996;13(3):411-20.
1996: Ram Sasisekharan; Ganesh Venkataraman; R Godavarti; S Ernst; C L Cooney; Robert Langer
Heparinase I from Flavobacterium heparinum. Mapping and characterization of the heparin binding domain.
The Journal of biological chemistry 1996;271(6):3124-31.
1996: Ganesh Venkataraman; V Sasisekharan; A B Herr; David M Ornitz; Gabriel Waksman; C L Cooney; Robert Langer; Ram Sasisekharan
Preferential self-association of basic fibroblast growth factor is stabilized by heparin during receptor dimerization and activation.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(2):845-50.
1996: Uwe Pliquett; thomas zewert; T Chen; Robert Langer; James C Weaver
Imaging of fluorescent molecule and small ion transport through human stratum corneum during high voltage pulsing: localized transport regions are involved.
Biophysical chemistry 1996;58(1-2):185-204.
1996: S P Schwendeman; Henry R Costantino; R K Gupta; M Tobio; A C Chang; María José Alonso; G R Siber; Robert Langer
Strategies for stabilising tetanus toxoid towards the development of a single-dose tetanus vaccine.
Developments in biological standardization 1996;87():293-306.
1996: Michael J Yaszemski; R G Payne; W C Hayes; Robert Langer; Antonios G Mikos
Evolution of bone transplantation: molecular, cellular and tissue strategies to engineer human bone.
Biomaterials 1996;17(2):175-85.
1996: D J Mooney; C L Mazzoni; C Breuer; K McNamara; D Hern; J P Vacanti; Robert Langer
Stabilized polyglycolic acid fibre-based tubes for tissue engineering.
Biomaterials 1996;17(2):115-24.
1995: T Shinoka; C K Breuer; R E Tanel; G Zund; T Miura; Peter X Ma; Robert Langer; J P Vacanti; John E Mayer
Tissue engineering heart valves: valve leaflet replacement study in a lamb model.
The Annals of thoracic surgery 1995;60(6 Suppl):S513-6.
1995: P X Ma; B Schloo; David Mooney; Robert Langer
Development of biomechanical properties and morphogenesis of in vitro tissue engineered cartilage.
Journal of biomedical materials research 1995;29(12):1587-95.
1995: S P Schwendeman; Henry R Costantino; R K Gupta; G R Siber; Alexander M Klibanov; Robert Langer
Stabilization of tetanus and diphtheria toxoids against moisture-induced aggregation.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(24):11234-8.
1995: Henry R Costantino; Kai Griebenow; P Mishra; Robert Langer; Alexander M Klibanov
Fourier-transform infrared spectroscopic investigation of protein stability in the lyophilized form.
Biochimica et biophysica acta 1995;1253(1):69-74.
1995: Ram Sasisekharan; D Leckband; R Godavarti; Ganesh Venkataraman; C L Cooney; Robert Langer
Heparinase I from Flavobacterium heparinum: the role of the cysteine residue in catalysis as probed by chemical modification and site-directed mutagenesis.
Biochemistry 1995;34(44):14441-8.
1995: Mark R Prausnitz; E R Edelman; J A Gimm; Robert Langer; James C Weaver
Transdermal delivery of heparin by skin electroporation.
Bio/technology (Nature Publishing Company) 1995;13(11):1205-9.
1995: Uwe Pliquett; Robert Langer; James C Weaver
Changes in the passive electrical properties of human stratum corneum due to electroporation.
Biochimica et biophysica acta 1995;1239(2):111-21.
1995: Mohamed Attawia; Kathryn E Uhrich; E Botchwey; M Fan; Robert Langer; Cato T Laurencin
Cytotoxicity testing of poly(anhydride-co-imides) for orthopedic applications.
Journal of biomedical materials research 1995;29(10):1233-40.
1995: M E Johnson; Daniel Blankschtein; Robert Langer
Permeation of steroids through human skin.
Journal of pharmaceutical sciences 1995;84(9):1144-6.
1995: Samir Mitragotri; Daniel Blankschtein; Robert Langer
Ultrasound-mediated transdermal protein delivery.
Science (New York, N.Y.) 1995;269(5225):850-3.
1995: D J Mooney; S Park; Peter M Kaufmann; K Sano; K McNamara; J P Vacanti; Robert Langer
Biodegradable sponges for hepatocyte transplantation.
Journal of biomedical materials research 1995;29(8):959-65.
1995: thomas zewert; Uwe Pliquett; Robert Langer; James C Weaver
Transdermal transport of DNA antisense oligonucleotides by electroporation.
Biochemical and biophysical research communications 1995;212(2):286-92.
1995: Ganesh Venkataraman; V Sasisekharan; C L Cooney; Robert Langer; Ram Sasisekharan
Complex flexibility of the transforming growth factor beta superfamily.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(12):5406-10.
1995: D J Mooney; Robert Langer; Donald Ingber
Cytoskeletal filament assembly and the control of cell spreading and function by extracellular matrix.
Journal of cell science 1995;108 ( Pt 6)():2311-20.
1995: Samir Mitragotri; D A Edwards; Daniel Blankschtein; Robert Langer
A mechanistic study of ultrasonically-enhanced transdermal drug delivery.
Journal of pharmaceutical sciences 1995;84(6):697-706.
1995: Henry R Costantino; Robert Langer; Alexander M Klibanov
Aggregation of a lyophilized pharmaceutical protein, recombinant human albumin: effect of moisture and stabilization by excipients.
Bio/technology (Nature Publishing Company) 1995;13(5):493-6.
1995: Mark R Prausnitz; J D Corbett; J A Gimm; David E Golan; Robert Langer; James C Weaver
Millisecond measurement of transport during and after an electroporation pulse.
Biophysical journal 1995;68(5):1864-70.
1995: M C Wake; Antonios G Mikos; G Sarakinos; J P Vacanti; Robert Langer
Dynamics of fibrovascular tissue ingrowth in hydrogel foams.
Cell transplantation 1995;4(3):275-9.
1995: J Okada; S Cohen; Robert Langer
In vitro evaluation of polymerized liposomes as an oral drug delivery system.
Pharmaceutical research 1995;12(4):576-82.
1995: S D Shefer; J Breslau; Robert Langer
Computer simulation of low-density lipoprotein removal in the presence of a bioreactor containing phospholipase A2.
Biotechnology progress 1995;11(2):133-9.
1995: Robert Langer
1994 Whitaker Lecture: polymers for drug delivery and tissue engineering.
Annals of biomedical engineering 1995;23(2):101-11.
1995: T Takeda; T H Kim; S K Lee; Robert Langer; J P Vacanti
Hepatocyte transplantation in biodegradable polymer scaffolds using the Dalmatian dog model of hyperuricosuria.
Transplantation proceedings 1995;27(1):635-6.
1995: Robert Langer; Joseph P Vacanti; Charles A Vacanti; Anthony Atala; Lisa E Freed; Gordana Vunjak-Novakovic
Tissue engineering: biomedical applications.
Tissue engineering 1995;1(2):151-61.
1995: David J Mooney; C Breuer; K McNamara; Joseph P Vacanti; Robert Langer
Fabricating tubular devices from polymers of lactic and glycolic Acid for tissue engineering.
Tissue engineering 1995;1(2):107-18.
1995: Michael J Yaszemski; R G Payne; W C Hayes; Robert Langer; T B Aufdemorte; Antonios G Mikos
The ingrowth of new bone tissue and initial mechanical properties of a degrading polymeric composite scaffold.
Tissue engineering 1995;1(1):41-52.
1995: S Ernst; Robert Langer; C L Cooney; Ram Sasisekharan
Enzymatic degradation of glycosaminoglycans.
Critical reviews in biochemistry and molecular biology 1995;30(5):387-444.
1995: Justin Hanes; M Chiba; Robert Langer
Polymer microspheres for vaccine delivery.
Pharmaceutical biotechnology 1995;6():389-412.
1994: D J Mooney; Peter M Kaufmann; K Sano; K M McNamara; J P Vacanti; Robert Langer
Transplantation of hepatocytes using porous, biodegradable sponges.
Transplantation proceedings 1994;26(6):3425-6.
1994: Y Cao; J P Vacanti; X Ma; K T Paige; J Upton; Z Chowanski; B Schloo; Robert Langer; Charles A Vacanti
Generation of neo-tendon using synthetic polymers seeded with tenocytes.
Transplantation proceedings 1994;26(6):3390-2.
1994: J Sakata; Charles A Vacanti; B Schloo; G B Healy; Robert Langer; J P Vacanti
Tracheal composites tissue engineered from chondrocytes, tracheal epithelial cells, and synthetic degradable scaffolding.
Transplantation proceedings 1994;26(6):3309-10.
1994: Mark R Prausnitz; Uwe Pliquett; Robert Langer; James C Weaver
Rapid temporal control of transdermal drug delivery by electroporation.
Pharmaceutical research 1994;11(12):1834-7.
1994: Henry R Costantino; Robert Langer; Alexander M Klibanov
Solid-phase aggregation of proteins under pharmaceutically relevant conditions.
Journal of pharmaceutical sciences 1994;83(12):1662-9.
1994: L Shieh; J Tamada; I Chen; J Pang; A Domb; Robert Langer
Erosion of a new family of biodegradable polyanhydrides.
Journal of biomedical materials research 1994;28(12):1465-75.
1994: D J Mooney; L K Hansen; Robert Langer; J P Vacanti; Donald Ingber
Extracellular matrix controls tubulin monomer levels in hepatocytes by regulating protein turnover.
Molecular biology of the cell 1994;5(12):1281-8.
1994: J P Ferreira; Ram Sasisekharan; O Louie; Robert Langer
A study on the functional subunits of phospholipases A2 by enzyme immobilization.
The Biochemical journal 1994;303 ( Pt 2)():527-30.
1994: D A Edwards; Robert Langer
A linear theory of transdermal transport phenomena.
Journal of pharmaceutical sciences 1994;83(9):1315-34.
1994: R A Rosenthal; Marsha A Moses; Y Shintani; J F Megyesi; Robert Langer; Judah Folkman
Purification and characterization of two collagenase inhibitors from mouse sarcoma 180 conditioned medium.
Journal of cellular biochemistry 1994;56(1):97-105.
1994: W C Puelacher; David Mooney; Robert Langer; J Upton; J P Vacanti; Charles A Vacanti
Design of nasoseptal cartilage replacements synthesized from biodegradable polymers and chondrocytes.
Biomaterials 1994;15(10):774-8.
1994: Lisa E Freed; D A Grande; Z Lingbin; J Emmanual; J C Marquis; Robert Langer
Joint resurfacing using allograft chondrocytes and synthetic biodegradable polymer scaffolds.
Journal of biomedical materials research 1994;28(8):891-9.
1994: J P Ferreira; Ram Sasisekharan; O Louie; Robert Langer
Carbodiimide modification enhances activity of pig pancreatic phospholipase A2.
European journal of biochemistry / FEBS 1994;223(2):611-6.
1994: Lynt B Johnson; J Aiken; David Mooney; B L Schloo; L Griffith-Cima; Robert Langer; J P Vacanti
The mesentery as a laminated vascular bed for hepatocyte transplantation.
Cell transplantation 1994;3(4):273-81.
1994: Lisa E Freed; Gordana Vunjak-Novakovic; R J Biron; D B Eagles; D C Lesnoy; S K Barlow; Robert Langer
Biodegradable polymer scaffolds for tissue engineering.
Bio/technology (Nature Publishing Company) 1994;12(7):689-93.
1994: Ganesh Venkataraman; V Sasisekharan; C L Cooney; Robert Langer; Ram Sasisekharan
A stereochemical approach to pyranose ring flexibility: its implications for the conformation of dermatan sulfate.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(13):6171-5.
1994: Mark R Prausnitz; C D Milano; J A Gimm; Robert Langer; James C Weaver
Quantitative study of molecular transport due to electroporation: uptake of bovine serum albumin by erythrocyte ghosts.
Biophysical journal 1994;66(5):1522-30.
1994: Wong Wong; Robert Langer; Donald Ingber
Electrically conducting polymers can noninvasively control the shape and growth of mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(8):3201-4.
1994: R Gref; Y Minamitake; M T Peracchia; V Trubetskoy; V Torchilin; Robert Langer
Biodegradable long-circulating polymeric nanospheres.
Science (New York, N.Y.) 1994;263(5153):1600-3.
1994: María José Alonso; R K Gupta; C Min; G R Siber; Robert Langer
Biodegradable microspheres as controlled-release tetanus toxoid delivery systems.
Vaccine 1994;12(4):299-306.
1994: M P Wu; J A Tamada; Henry Brem; Robert Langer
In vivo versus in vitro degradation of controlled release polymers for intracranial surgical therapy.
Journal of biomedical materials research 1994;28(3):387-95.
1994: D J Mooney; G Organ; J P Vacanti; Robert Langer
Design and fabrication of biodegradable polymer devices to engineer tubular tissues.
Cell transplantation 1994;3(2):203-10.
1994: Ram Sasisekharan; Marsha A Moses; Matthew A Nugent; C L Cooney; Robert Langer
Heparinase inhibits neovascularization.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(4):1524-8.
1994: Antonios G Mikos; M D Lyman; Lisa E Freed; Robert Langer
Wetting of poly(L-lactic acid) and poly(DL-lactic-co-glycolic acid) foams for tissue culture.
Biomaterials 1994;15(1):55-8.
1994: Henry R Costantino; Robert Langer; Alexander M Klibanov
Moisture-induced aggregation of lyophilized insulin.
Pharmaceutical research 1994;11(1):21-9.
1994: Y Tabata; A Domb; Robert Langer
Injectable polyanhydride granules provide controlled release of water-soluble drugs with a reduced initial burst.
Journal of pharmaceutical sciences 1994;83(1):5-11.
1993: Mark R Prausnitz; V G Bose; Robert Langer; James C Weaver
Electroporation of mammalian skin: a mechanism to enhance transdermal drug delivery.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(22):10504-8.
1993: David Masters; Charles B Berde; S Dutta; Thomas Turek; Robert Langer
Sustained local anesthetic release from bioerodible polymer matrices: a potential method for prolonged regional anesthesia.
Pharmaceutical research 1993;10(10):1527-32.
1993: J P Ferreira; Ram Sasisekharan; O Louie; Robert Langer
Influence of chemistry in immobilization of cobra venom phospholipase A2: implications as to mechanism.
Biochemistry 1993;32(32):8098-102.
1993: David Masters; Charles B Berde; S K Dutta; C T Griggs; D Hu; William J Kupsky; Robert Langer
Prolonged regional nerve blockade by controlled release of local anesthetic from a biodegradable polymer matrix.
Anesthesiology 1993;79(2):340-6.
1993: Elazer R Edelman; Robert Langer
Optimization of release from magnetically controlled polymeric drug release devices.
Biomaterials 1993;14(8):621-6.
1993: María José Alonso; S Cohen; T G Park; R K Gupta; G R Siber; Robert Langer
Determinants of release rate of tetanus vaccine from polyester microspheres.
Pharmaceutical research 1993;10(7):945-53.
1993: Mark R Prausnitz; B S Lau; C D Milano; S Conner; Robert Langer; James C Weaver
A quantitative study of electroporation showing a plateau in net molecular transport.
Biophysical journal 1993;65(1):414-22.
1993: Robert Langer; J P Vacanti
Tissue engineering.
Science (New York, N.Y.) 1993;260(5110):920-6.
1993: E Ron; Thomas Turek; E Mathiowitz; M Chasin; M Hageman; Robert Langer
Controlled release of polypeptides from polyanhydrides.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(9):4176-80.
1993: Ram Sasisekharan; M Bulmer; Kelley W Moremen; C L Cooney; Robert Langer
Cloning and expression of heparinase I gene from Flavobacterium heparinum.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3660-4.
1993: R Labeque; C J Mullon; J P Ferreira; R S Lees; Robert Langer
Enzymatic modification of plasma low density lipoproteins in rabbits: a potential treatment for hypercholesterolemia.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3476-80.
1993: Antonios G Mikos; G Sarakinos; S M Leite; J P Vacanti; Robert Langer
Laminated three-dimensional biodegradable foams for use in tissue engineering.
Biomaterials 1993;14(5):323-30.
1993: Y Tabata; S Gutta; Robert Langer
Controlled delivery systems for proteins using polyanhydride microspheres.
Pharmaceutical research 1993;10(4):487-96.
1993: S D Shefer; J Ferreira; C J Mullon; Robert Langer
Extracorporeal enzymatic removal of low density lipoproteins in rabbits: efficacy and safety.
The International journal of artificial organs 1993;16(4):218-28.
1993: Lisa E Freed; Gordana Vunjak-Novakovic; Robert Langer
Cultivation of cell-polymer cartilage implants in bioreactors.
Journal of cellular biochemistry 1993;51(3):257-64.
1993: C T Laurencin; T Gerhart; P Witschger; R Satcher; A Domb; Andrew E Rosenberg; P Hanff; L Edsberg; W Hayes; Robert Langer
Bioerodible polyanhydrides for antibiotic drug delivery: in vivo osteomyelitis treatment in a rat model system.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1993;11(2):256-62.
1993: Y Tabata; Robert Langer
Polyanhydride microspheres that display near-constant release of water-soluble model drug compounds.
Pharmaceutical research 1993;10(3):391-9.
1993: M Fontaine; L K Hansen; S Thompson; S Uyama; Donald Ingber; Robert Langer; J P Vacanti
Transplantation of genetically altered hepatocytes using cell-polymer constructs.
Transplantation proceedings 1993;25(1 Pt 2):1002-4.
1993: Antonios G Mikos; Y Bao; L G Cima; Donald Ingber; J P Vacanti; Robert Langer
Preparation of poly(glycolic acid) bonded fiber structures for cell attachment and transplantation.
Journal of biomedical materials research 1993;27(2):183-9.
1993: J A Tamada; Robert Langer
Erosion kinetics of hydrolytically degradable polymers.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(2):552-6.
1993: H L Wald; G Sarakinos; M D Lyman; Antonios G Mikos; J P Vacanti; Robert Langer
Cell seeding in porous transplantation devices.
Biomaterials 1993;14(4):270-8.
1993: Lisa E Freed; Gordana Vunjak-Novakovic; H Bernstein; C L Cooney; Robert Langer
Kinetics of immobilized heparinase in human blood.
Annals of biomedical engineering 1993;21(1):67-76.
1993: Lisa E Freed; Gordana Vunjak-Novakovic; P A Drinker; Robert Langer
Bioreactor based on suspended particles of immobilized enzyme.
Annals of biomedical engineering 1993;21(1):57-65.
1993: Lisa E Freed; J C Marquis; A Nohria; J Emmanual; Antonios G Mikos; Robert Langer
Neocartilage formation in vitro and in vivo using cells cultured on synthetic biodegradable polymers.
Journal of biomedical materials research 1993;27(1):11-23.
1992: A D'Emanuele; J Hill; J A Tamada; A J Domb; Robert Langer
Molecular weight changes in polymer erosion.
Pharmaceutical research 1992;9(10):1279-83.
1992: Michael Simons; Elazer R Edelman; J L DeKeyser; Robert Langer; R D Rosenberg
Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo.
Nature 1992;359(6390):67-70.
1992: P J Soltys; C Mullon; Robert Langer
Oral treatment for jaundice using immobilized bilirubin oxidase.
Artificial organs 1992;16(4):331-5.
1992: David Mooney; L Hansen; J Vacanti; Robert Langer; S Farmer; Donald Ingber
Switching from differentiation to growth in hepatocytes: control by extracellular matrix.
Journal of cellular physiology 1992;151(3):497-505.
1992: Matthew J During; Andrew Freese; Ariel Deutch; P G Kibat; Bernhard A Sabel; Robert Langer; Robert H Roth
Biochemical and behavioral recovery in a rodent model of Parkinson's disease following stereotactic implantation of dopamine-containing liposomes.
Experimental neurology 1992;115(2):193-9.
1992: T G Park; S Cohen; Robert Langer
Controlled protein release from polyethyleneimine-coated poly(L-lactic acid)/pluronic blend matrices.
Pharmaceutical research 1992;9(1):37-9.
1992: Erich Wintermantel; L Cima; B Schloo; Robert Langer
Angiopolarity of cell carriers: directional angiogenesis in resorbable liver cell transplantation devices.
EXS 1992;61():331-4.
1992: J Tamada; Robert Langer
The development of polyanhydrides for drug delivery applications.
Journal of biomaterials science. Polymer edition 1992;3(4):315-53.
1991: S Cohen; H Bernstein; C Hewes; M Chow; Robert Langer
The pharmacokinetics of, and humoral responses to, antigen delivered by microencapsulated liposomes.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(23):10440-4.
1991: V Sluzky; J A Tamada; Alexander M Klibanov; Robert Langer
Kinetics of insulin aggregation in aqueous solutions upon agitation in the presence of hydrophobic surfaces.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(21):9377-81.
1991: Elazer R Edelman; E Mathiowitz; Robert Langer; M Klagsbrun
Controlled and modulated release of basic fibroblast growth factor.
Biomaterials 1991;12(7):619-26.
1991: Erich Wintermantel; L Cima; B Schloo; Robert Langer
Angiopolarity: a new design parameter for cell transplantation devices and its application to degradable systems.
ASAIO transactions / American Society for Artificial Internal Organs 1991;37(3):M334-6.
1991: L G Cima; J P Vacanti; Charles A Vacanti; Donald Ingber; David Mooney; Robert Langer
Tissue engineering by cell transplantation using degradable polymer substrates.
Journal of biomechanical engineering 1991;113(2):143-51.
1991: M Carmen Bañó; S Cohen; K B Visscher; Harry R Allcock; Robert Langer
A novel synthetic method for hybridoma cell encapsulation.
Bio/technology (Nature Publishing Company) 1991;9(5):468-71.
1991: Robert Langer; Marsha A Moses
Biocompatible controlled release polymers for delivery of polypeptides and growth factors.
Journal of cellular biochemistry 1991;45(4):340-5.
1991: Robert Langer; J Kost
Real time response polymeric delivery systems.
Annals of the New York Academy of Sciences 1991;618():330-4.
1990: C Laurencin; Abraham J Domb; C Morris; V Brown; M Chasin; R McConnell; N Lange; Robert Langer
Poly(anhydride) administration in high doses in vivo: studies of biocompatibility and toxicology.
Journal of biomedical materials research 1990;24(11):1463-81.
1990: Robert Langer; L G Cima; J A Tamada; Erich Wintermantel
Future directions in biomaterials.
Biomaterials 1990;11(9):738-45.
1990: Robert Langer
New methods of drug delivery.
Science (New York, N.Y.) 1990;249(4976):1527-33.
1990: Cato T Laurencin; H M Pierre-Jacques; Robert Langer
Toxicology and biocompatibility considerations in the evaluation of polymeric materials for biomedical applications.
Clinics in laboratory medicine 1990;10(3):549-70.
1990: Paul A Lucas; C Laurencin; G T Syftestad; Abraham J Domb; Victor M Goldberg; Arnold I Caplan; Robert Langer
Ectopic induction of cartilage and bone by water-soluble proteins from bovine bone using a polyanhydride delivery vehicle.
Journal of biomedical materials research 1990;24(7):901-11.
1990: E Mathiowitz; D Kline; Robert Langer
Morphology of polyanhydride microsphere delivery systems.
Scanning microscopy 1990;4(2):329-40.
1990: P G Kibat; Y Igari; M A Wheatley; H N Eisen; Robert Langer
Enzymatically activated microencapsulated liposomes can provide pulsatile drug release.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1990;4(8):2533-9.
1990: J Aiken; L Cima; B Schloo; David Mooney; L Johnson; Robert Langer; J P Vacanti
Studies in rat liver perfusion for optimal harvest of hepatocytes.
Journal of pediatric surgery 1990;25(1):140-4; discussion 144-5.
1989: Matthew J During; Andrew Freese; Bernhard A Sabel; W M Saltzman; Ariel Deutch; Robert H Roth; Robert Langer
Controlled release of dopamine from a polymeric brain implant: in vivo characterization.
Annals of neurology 1989;25(4):351-6.
1989: Andrew Freese; Bernhard A Sabel; W M Saltzman; M J During; Robert Langer
Controlled release of dopamine from a polymeric brain implant: in vitro characterization.
Experimental neurology 1989;103(3):234-8.
1989: A K Larsen; K G Rice; R J Linhardt; G Wogan; Robert Langer
Resistance of heparinase-derived heparin fragments to biotransformation.
The Journal of biological chemistry 1989;264(3):1570-7.
1988: H Bernstein; Robert Langer
Ex vivo model of an immobilized-enzyme reactor.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(22):8751-5.
1988: Robert Langer
Biodegradable polymers for drug delivery to the brain.
ASAIO transactions / American Society for Artificial Internal Organs 1988;34(4):945-6.
1988: C Bindschaedler; K Leong; E Mathiowitz; Robert Langer
Polyanhydride microsphere formulation by solvent extraction.
Journal of pharmaceutical sciences 1988;77(8):696-8.
1988: Lisa E Freed; G V Vunjak; P A Drinker; Robert Langer
A novel bioreactor based on suspended particles of agarose-immobilized species.
ASAIO transactions / American Society for Artificial Internal Organs 1988;34(3):732-8.
1988: F Fischel-Ghodsian; L Brown; E Mathiowitz; D Brandenburg; Robert Langer
Enzymatically controlled drug delivery.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(7):2403-6.
1988: H Bernstein; V C Yang; C L Cooney; Robert Langer
Immobilized heparin lyase system for blood deheparinization.
Methods in enzymology 1988;137():515-29.
1988: L Brown; Robert Langer
Transdermal delivery of drugs.
Annual review of medicine 1988;39():221-9.
1988: J P Vacanti; M A Morse; W M Saltzman; A J Domb; Antonio Perez-Atayde; Robert Langer
Selective cell transplantation using bioabsorbable artificial polymers as matrices.
Journal of pediatric surgery 1988;23(1 Pt 2):3-9.
1987: J Kost; J Wolfrum; Robert Langer
Magnetically enhanced insulin release in diabetic rats.
Journal of biomedical materials research 1987;21(12):1367-73.
1987: Cato T Laurencin; H J Koh; T X Neenan; Harry R Allcock; Robert Langer
Controlled release using a new bioerodible polyphosphazene matrix system.
Journal of biomedical materials research 1987;21(10):1231-46.
1987: V C Yang; H Bernstein; C L Cooney; Robert Langer
Large scale preparation and characterization of mucopolysaccharase contamination free heparinase.
Applied biochemistry and biotechnology 1987;16():35-50.
1987: H Bernstein; V C Yang; Robert Langer
An investigation of heparinase immobilization.
Applied biochemistry and biotechnology 1987;16():129-43.
1986: V C Yang; H Bernstein; C L Cooney; J C Kadam; Robert Langer
Removal of the anticoagulant activities of the low molecular weight heparin fractions and fragments with flavobacterial heparinase.
Thrombosis research 1986;44(5):599-610.
1985: K W Leong; B C Brott; Robert Langer
Bioerodible polyanhydrides as drug-carrier matrices. I: Characterization, degradation, and release characteristics.
Journal of biomedical materials research 1985;19(8):941-55.
1985: J Kost; R Noecker; E Kunica; Robert Langer
Magnetically controlled release systems: effect of polymer composition.
Journal of biomedical materials research 1985;19(8):935-40.
1985: V C Yang; R J Linhardt; H Bernstein; C L Cooney; Robert Langer
Purification and characterization of heparinase from Flavobacterium heparinum.
The Journal of biological chemistry 1985;260(3):1849-57.