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Robert Langer

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

TOP 3
Hook Andrew L; Anderson Daniel G; Langer Robert; Williams Paul; Davies Martyn C; Alexander Morgan R
High throughput methods applied in biomaterial development and discovery.
Gerecht Sharon; Ferreira Lino S; Langer Robert
Vascular differentiation of human embryonic stem cells in bioactive hydrogel-based scaffolds.
Dang Tram T; Xu Qiaobing; Bratlie Kaitlin M; O'Sullivan Esther S; Chen Xiao Y; Langer Robert; Anderson Daniel G
Microfabrication of homogenous, asymmetric cell-laden hydrogel capsules.

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All Publications

2010: Hook Andrew L; Anderson Daniel G; Langer Robert; Williams Paul; Davies Martyn C; Alexander Morgan R
High throughput methods applied in biomaterial development and discovery.
Biomaterials 2010;31(2):187-98.
2010: Gerecht Sharon; Ferreira Lino S; Langer Robert
Vascular differentiation of human embryonic stem cells in bioactive hydrogel-based scaffolds.
Methods in molecular biology (Clifton, N.J.) 2010;584():333-54.
2009: Dang Tram T; Xu Qiaobing; Bratlie Kaitlin M; O'Sullivan Esther S; Chen Xiao Y; Langer Robert; Anderson Daniel G
Microfabrication of homogenous, asymmetric cell-laden hydrogel capsules.
Biomaterials 2009;30(36):6896-902.
2009: Bettinger Christopher J; Bruggeman Joost P; Borenstein Jeffrey T; Langer Robert
In vitro and in vivo degradation of poly(1,3-diamino-2-hydroxypropane-co-polyol sebacate) elastomers.
Journal of biomedical materials research. Part A 2009;91(4):1077-88.
2009: George Paul M; Saigal Rajiv; Lawlor Michael W; Moore Michael J; LaVan David A; Marini Robert P; Selig Martin; Makhni Melvin; Burdick Jason A; Langer Robert; Kohane Daniel S
Three-dimensional conductive constructs for nerve regeneration.
Journal of biomedical materials research. Part A 2009;91(2):519-27.
2009: Nguyen David N; Chen Steve C-Y; Lu James; Goldberg Michael; Kim Phillip; Sprague Andrew; Novobrantseva Tatiana; Sherman Jennifer; Shulga-Morskaya Svetlana; de Fougerolles Antonin; Chen Jianzhu; Langer Robert; Anderson Daniel G
Drug delivery-mediated control of RNA immunostimulation.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(9):1555-62.
2009: Kraehenbuehl Thomas P; Ferreira Lino S; Zammaretti Prisca; Hubbell Jeffrey A; Langer Robert
Cell-responsive hydrogel for encapsulation of vascular cells.
Biomaterials 2009;30(26):4318-24.
2009: Huang Yu-Hung; Zugates Gregory T; Peng Weidan; Holtz David; Dunton Charles; Green Jordan J; Hossain Naushad; Chernick Michael R; Padera Robert F; Langer Robert; Anderson Daniel G; Sawicki Janet A
Nanoparticle-delivered suicide gene therapy effectively reduces ovarian tumor burden in mice.
Cancer research 2009;69(15):6184-91.
2009: Yang Fan; Mei Ying; Langer Robert; Anderson Daniel G
High throughput optimization of stem cell microenvironments.
Combinatorial chemistry & high throughput screening 2009;12(6):554-61.
2009: Daniel Karen D; Kim Grace Y; Vassiliou Christophoros C; Galindo Marilyn; Guimaraes Alexander R; Weissleder Ralph; Charest Al; Langer Robert; Cima Michael J
Implantable diagnostic device for cancer monitoring.
Biosensors & bioelectronics 2009;24(11):3252-7.
2009: Redenti Stephen; Neeley William L; Rompani Santiago; Saigal Sunita; Yang Jing; Klassen Henry; Langer Robert; Young Michael J
Engineering retinal progenitor cell and scrollable poly(glycerol-sebacate) composites for expansion and subretinal transplantation.
Biomaterials 2009;30(20):3405-14.
2009: Nguyen David N; Kim Phillip; Martínez-Sobrido Luis; Beitzel Brett; García-Sastre Adolfo; Langer Robert; Anderson Daniel G
A novel high-throughput cell-based method for integrated quantification of type I interferons and in vitro screening of immunostimulatory RNA drug delivery.
Biotechnology and bioengineering 2009;103(4):664-75.
2009: Xu Qiaobing; Hashimoto Michinao; Dang Tram T; Hoare Todd; Kohane Daniel S; Whitesides George M; Langer Robert; Anderson Daniel G
Preparation of monodisperse biodegradable polymer microparticles using a microfluidic flow-focusing device for controlled drug delivery.
Small (Weinheim an der Bergstrasse, Germany) 2009;5(13):1575-81.
2009: Lee Jae-Seung; Green Jordan J; Love Kevin T; Sunshine Joel; Langer Robert; Anderson Daniel G
Gold, poly(beta-amino ester) nanoparticles for small interfering RNA delivery.
Nano letters 2009;9(6):2402-6.
2009: Bettinger Christopher J; Kulig Katherine M; Vacanti Joseph P; Langer Robert; Borenstein Jeffrey T
Nanofabricated collagen-inspired synthetic elastomers for primary rat hepatocyte culture.
Tissue engineering. Part A 2009;15(6):1321-9.
2009: Lu James J; Langer Robert; Chen Jianzhu
A novel mechanism is involved in cationic lipid-mediated functional siRNA delivery.
Molecular pharmaceutics 2009;6(3):763-71.
2009: Akinc Akin; Goldberg Michael; Qin June; Dorkin J Robert; Gamba-Vitalo Christina; Maier Martin; Jayaprakash K Narayanannair; Jayaraman Muthusamy; Rajeev Kallanthottathil G; Manoharan Muthiah; Koteliansky Victor; Röhl Ingo; Leshchiner Elizaveta S; Langer Robert; Anderson Daniel G
Development of lipidoid-siRNA formulations for systemic delivery to the liver.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(5):872-9.
2009: Salvador-Morales Carolina; Zhang Liangfang; Langer Robert; Farokhzad Omid C
Immunocompatibility properties of lipid-polymer hybrid nanoparticles with heterogeneous surface functional groups.
Biomaterials 2009;30(12):2231-40.
2009: Yang F; Green J J; Dinio T; Keung L; Cho S-W; Park H; Langer R; Anderson D G
Gene delivery to human adult and embryonic cell-derived stem cells using biodegradable nanoparticulate polymeric vectors.
Gene therapy 2009;16(4):533-46.
2009: Chan Juliana M; Zhang Liangfang; Yuet Kai P; Liao Grace; Rhee June-Wha; Langer Robert; Farokhzad Omid C
PLGA-lecithin-PEG core-shell nanoparticles for controlled drug delivery.
Biomaterials 2009;30(8):1627-34.
2009: Shapiro Mikhail G; Szablowski Jerzy O; Langer Robert; Jasanoff Alan
Protein nanoparticles engineered to sense kinase activity in MRI.
Journal of the American Chemical Society 2009;131(7):2484-6.
2009: Salvador-Morales Carolina; Gao Weiwei; Ghatalia Pooja; Murshed Farhan; Aizu Wataru; Langer Robert; Farokhzad Omid C
Multifunctional nanoparticles for prostate cancer therapy.
Expert review of anticancer therapy 2009;9(2):211-21.
2009: Whitehead Kathryn A; Langer Robert; Anderson Daniel G
Knocking down barriers: advances in siRNA delivery.
Nature reviews. Drug discovery 2009;8(2):129-38.
2009: Stone Geoffrey W; Barzee Suzanne; Snarsky Victoria; Santucci Camila; Tran Brian; Langer Robert; Zugates Gregory T; Anderson Daniel G; Kornbluth Richard S
Nanoparticle-delivered multimeric soluble CD40L DNA combined with Toll-Like Receptor agonists as a treatment for melanoma.
PloS one 2009;4(10):e7334.
2009: Bettinger Christopher J; Langer Robert; Borenstein Jeffrey T
Engineering substrate topography at the micro- and nanoscale to control cell function.
Angewandte Chemie (International ed. in English) 2009;48(30):5406-15.
2009: Gu Frank; Langer Robert; Farokhzad Omid C
Formulation/preparation of functionalized nanoparticles for in vivo targeted drug delivery.
Methods in molecular biology (Clifton, N.J.) 2009;544():589-98.
2008: Zhang Liangfang; Chan Juliana M; Gu Frank X; Rhee June-Wha; Wang Andrew Z; Radovic-Moreno Aleksandar F; Alexis Frank; Langer Robert; Farokhzad Omid C
Self-assembled lipid--polymer hybrid nanoparticles: a robust drug delivery platform.
ACS nano 2008;2(8):1696-702.
2008: Parsa Saba; Wang Yong; Fuller Jason; Langer Robert; Pfeifer Blaine A
A comparison between polymeric microsphere and bacterial vectors for macrophage P388D1 gene delivery.
Pharmaceutical research 2008;25(5):1202-8.
2008: Zhang L; Gu F X; Chan J M; Wang A Z; Langer R S; Farokhzad O C
Nanoparticles in medicine: therapeutic applications and developments.
Clinical pharmacology and therapeutics 2008;83(5):761-9.
2008: Wright Dylan; Rajalingam Bimalraj; Karp Jeffrey M; Selvarasah Selvapraba; Ling Yibo; Yeh Judy; Langer Robert; Dokmeci Mehmet R; Khademhosseini Ali
Reusable, reversibly sealable parylene membranes for cell and protein patterning.
Journal of biomedical materials research. Part A 2008;85(2):530-8.
2008: Karnik Rohit; Hong Seungpyo; Zhang Huanan; Mei Ying; Anderson Daniel G; Karp Jeffrey M; Langer Robert
Nanomechanical control of cell rolling in two dimensions through surface patterning of receptors.
Nano letters 2008;8(4):1153-8.
2008: Mahdavi Alborz; Ferreira Lino; Sundback Cathryn; Nichol Jason W; Chan Edwin P; Carter David J D; Bettinger Chris J; Patanavanich Siamrut; Chignozha Loice; Ben-Joseph Eli; Galakatos Alex; Pryor Howard; Pomerantseva Irina; Masiakos Peter T; Faquin William; Zumbuehl Andreas; Hong Seungpyo; Borenstein Jeffrey; Vacanti Joseph; Langer Robert; Karp Jeffrey M
A biodegradable and biocompatible gecko-inspired tissue adhesive.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2307-12.
2008: Gu Frank; Zhang Liangfang; Teply Benjamin A; Mann Nina; Wang Andrew; Radovic-Moreno Aleksandar F; Langer Robert; Farokhzad Omid C
Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2586-91.
2008: Wood Kris C; Azarin Samira M; Arap Wadih; Pasqualini Renata; Langer Robert; Hammond Paula T
Tumor-targeted gene delivery using molecularly engineered hybrid polymers functionalized with a tumor-homing peptide.
Bioconjugate chemistry 2008;19(2):403-5.
2008: Neeley William L; Redenti Stephen; Klassen Henry; Tao Sarah; Desai Tejal; Young Michael J; Langer Robert
A microfabricated scaffold for retinal progenitor cell grafting.
Biomaterials 2008;29(4):418-26.
2008: Kushner Joseph; Blankschtein Daniel; Langer Robert
Evaluation of hydrophilic permeant transport parameters in the localized and non-localized transport regions of skin treated simultaneously with low-frequency ultrasound and sodium lauryl sulfate.
Journal of pharmaceutical sciences 2008;97(2):906-18.
2008: Kang Lifeng; Chung Bong Geun; Langer Robert; Khademhosseini Ali
Microfluidics for drug discovery and development: from target selection to product lifecycle management.
Drug discovery today 2008;13(1-2):1-13.
2008: Alexis Frank; Rhee June-Wha; Richie Jerome P; Radovic-Moreno Aleksandar F; Langer Robert; Farokhzad Omid C
New frontiers in nanotechnology for cancer treatment.
Urologic oncology 2008;26(1):74-85.
2007: Adams Dana R; Toner Mehmet; Langer Robert
Role of trehalose in prevention of giant vesicle adsorption and encapsulated solute leakage in anhydrobiotic preservation.
Langmuir : the ACS journal of surfaces and colloids 2007;23(26):13013-23.
2007: Kushner Joseph; Blankschtein Daniel; Langer Robert
Evaluation of the porosity, the tortuosity, and the hindrance factor for the transdermal delivery of hydrophilic permeants in the context of the aqueous pore pathway hypothesis using dual-radiolabeled permeability experiments.
Journal of pharmaceutical sciences 2007;96(12):3263-82.
2007: Kushner Joseph; Deen William; Blankschtein Daniel; Langer Robert
First-principles, structure-based transdermal transport model to evaluate lipid partition and diffusion coefficients of hydrophobic permeants solely from stratum corneum permeation experiments.
Journal of pharmaceutical sciences 2007;96(12):3236-51.
2007: Evgenov Oleg V; Kohane Daniel S; Bloch Kenneth D; Stasch Johannes-Peter; Volpato Gian P; Bellas Evangelia; Evgenov Natalia V; Buys Emmanuel S; Gnoth Mark J; Graveline Amanda R; Liu Rong; Hess Dean R; Langer Robert; Zapol Warren M
Inhaled agonists of soluble guanylate cyclase induce selective pulmonary vasodilation.
American journal of respiratory and critical care medicine 2007;176(11):1138-45.
2007: Townsend Seth A; Evrony Gilad D; Gu Frank X; Schulz Martin P; Brown Robert H; Langer Robert
Tetanus toxin C fragment-conjugated nanoparticles for targeted drug delivery to neurons.
Biomaterials 2007;28(34):5176-84.
2007: Khademhosseini Ali; Langer Robert
Microengineered hydrogels for tissue engineering.
Biomaterials 2007;28(34):5087-92.
2007: Hong Seungpyo; Lee Dooyoung; Zhang Huanan; Zhang Jennifer Q; Resvick Jennifer N; Khademhosseini Ali; King Michael R; Langer Robert; Karp Jeffrey M
Covalent immobilization of p-selectin enhances cell rolling.
Langmuir : the ACS journal of surfaces and colloids 2007;23(24):12261-8.
2007: Zugates Gregory T; Tedford Nathan C; Zumbuehl Andreas; Jhunjhunwala Siddharth; Kang Christina S; Griffith Linda G; Lauffenburger Douglas A; Langer Robert; Anderson Daniel G
Gene delivery properties of end-modified poly(beta-amino ester)s.
Bioconjugate chemistry 2007;18(6):1887-96.
2007: Kim Grace Y; Josephson Lee; Langer Robert; Cima Michael J
Magnetic relaxation switch detection of human chorionic gonadotrophin.
Bioconjugate chemistry 2007;18(6):2024-8.
2007: Gerecht Sharon; Townsend Seth A; Pressler Heather; Zhu Han; Nijst Christiaan L E; Bruggeman Joost P; Nichol Jason W; Langer Robert
A porous photocurable elastomer for cell encapsulation and culture.
Biomaterials 2007;28(32):4826-35.
2007: Karp Jeffrey M; Langer Robert
Development and therapeutic applications of advanced biomaterials.
Current opinion in biotechnology 2007;18(5):454-9.
2007: John Matthias; Constien Rainer; Akinc Akin; Goldberg Michael; Moon Young-Ah; Spranger Martina; Hadwiger Philipp; Soutschek Jürgen; Vornlocher Hans-Peter; Manoharan Muthiah; Stoffel Markus; Langer Robert; Anderson Daniel G; Horton Jay D; Koteliansky Victor; Bumcrot David
Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway.
Nature 2007;449(7163):745-7.
2007: Daniel Karen D; Kim Grace Y; Vassiliou Christophoros C; Jalali-Yazdi Farzad; Langer Robert; Cima Michael J
Multi-reservoir device for detecting a soluble cancer biomarker.
Lab on a chip 2007;7(10):1288-93.
2007: Bagalkot Vaishali; Zhang Liangfang; Levy-Nissenbaum Etgar; Jon Sangyong; Kantoff Philip W; Langer Robert; Farokhzad Omid C
Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer.
Nano letters 2007;7(10):3065-70.
2007: Nijst Christiaan L E; Bruggeman Joost P; Karp Jeffrey M; Ferreira Lino; Zumbuehl Andreas; Bettinger Christopher J; Langer Robert
Synthesis and characterization of photocurable elastomers from poly(glycerol-co-sebacate).
Biomacromolecules 2007;8(10):3067-73.
2007: Gerecht Sharon; Bettinger Christopher J; Zhang Zhitong; Borenstein Jeffrey T; Vunjak-Novakovic Gordana; Langer Robert
The effect of actin disrupting agents on contact guidance of human embryonic stem cells.
Biomaterials 2007;28(28):4068-77.
2007: Yeo Yoon; Bellas Evangelia; Highley Christopher B; Langer Robert; Kohane Daniel S
Peritoneal adhesion prevention with an in situ cross-linkable hyaluronan gel containing tissue-type plasminogen activator in a rabbit repeated-injury model.
Biomaterials 2007;28(25):3704-13.
2007: Zumbuehl Andreas; Ferreira Lino; Kuhn Duncan; Astashkina Anna; Long Lisa; Yeo Yoon; Iaconis Tiffany; Ghannoum Mahmoud; Fink Gerald R; Langer Robert; Kohane Daniel S
Antifungal hydrogels.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(32):12994-8.
2007: Radisic M; Park H; Gerecht S; Cannizzaro C; Langer R; Vunjak-Novakovic G
Biomimetic approach to cardiac tissue engineering.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2007;362(1484):1357-68.
2007: Ferreira Lino S; Gerecht Sharon; Shieh Hester F; Watson Nicki; Rupnick Maria A; Dallabrida Susan M; Vunjak-Novakovic Gordana; Langer Robert
Vascular progenitor cells isolated from human embryonic stem cells give rise to endothelial and smooth muscle like cells and form vascular networks in vivo.
Circulation research 2007;101(3):286-94.
2007: Park Hyoungshin; Cannizzaro Christopher; Vunjak-Novakovic Gordana; Langer Robert; Vacanti Charles A; Farokhzad Omid C
Nanofabrication and microfabrication of functional materials for tissue engineering.
Tissue engineering 2007;13(8):1867-77.
2007: Levenberg Shulamit; Zoldan Janet; Basevitch Yaara; Langer Robert
Endothelial potential of human embryonic stem cells.
Blood 2007;110(3):806-14.
2007: Gerecht Sharon; Burdick Jason A; Ferreira Lino S; Townsend Seth A; Langer Robert; Vunjak-Novakovic Gordana
Hyaluronic acid hydrogel for controlled self-renewal and differentiation of human embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(27):11298-303.
2007: Zugates Gregory T; Peng Weidan; Zumbuehl Andreas; Jhunjhunwala Siddharth; Huang Yu-Hung; Langer Robert; Sawicki Janet A; Anderson Daniel G
Rapid optimization of gene delivery by parallel end-modification of poly(beta-amino ester)s.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(7):1306-12.
2007: Karp Jeffrey M; Yeh Judy; Eng George; Fukuda Junji; Blumling James; Suh Kahp-Yang; Cheng Jianjun; Mahdavi Alborz; Borenstein Jeffrey; Langer Robert; Khademhosseini Ali
Controlling size, shape and homogeneity of embryoid bodies using poly(ethylene glycol) microwells.
Lab on a chip 2007;7(6):786-94.
2007: Figallo Elisa; Cannizzaro Christopher; Gerecht Sharon; Burdick Jason A; Langer Robert; Elvassore Nicola; Vunjak-Novakovic Gordana
Micro-bioreactor array for controlling cellular microenvironments.
Lab on a chip 2007;7(6):710-9.
2007: Ferreira Lino S; Gerecht Sharon; Fuller Jason; Shieh Hester F; Vunjak-Novakovic Gordana; Langer Robert
Bioactive hydrogel scaffolds for controllable vascular differentiation of human embryonic stem cells.
Biomaterials 2007;28(17):2706-17.
2007: Green Jordan J; Chiu Eugene; Leshchiner Elizaveta S; Shi Julie; Langer Robert; Anderson Daniel G
Electrostatic ligand coatings of nanoparticles enable ligand-specific gene delivery to human primary cells.
Nano letters 2007;7(4):874-9.
2007: Khademhosseini Ali; Eng George; Yeh Judy; Kucharczyk Peter A; Langer Robert; Vunjak-Novakovic Gordana; Radisic Milica
Microfluidic patterning for fabrication of contractile cardiac organoids.
Biomedical microdevices 2007;9(2):149-57.
2007: Choleris Elena; Little Steven R; Mong Jessica A; Puram Sidharth V; Langer Robert; Pfaff Donald W
Microparticle-based delivery of oxytocin receptor antisense DNA in the medial amygdala blocks social recognition in female mice.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(11):4670-5.
2007: Ward M S; Khoobehi A; Lavik E B; Langer R; Young M J
Neuroprotection of retinal ganglion cells in DBA/2J mice with GDNF-loaded biodegradable microspheres.
Journal of pharmaceutical sciences 2007;96(3):558-68.
2007: Cheng Jianjun; Teply Benjamin A; Sherifi Ines; Sung Josephine; Luther Gaurav; Gu Frank X; Levy-Nissenbaum Etgar; Radovic-Moreno Aleksandar F; Langer Robert; Farokhzad Omid C
Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery.
Biomaterials 2007;28(5):869-76.
2007: Jiang Caihui; Moore Michael J; Zhang Xinmei; Klassen Henry; Langer Robert; Young Michael
Intravitreal injections of GDNF-loaded biodegradable microspheres are neuroprotective in a rat model of glaucoma.
Molecular vision 2007;13():1783-92.
2007: Goldberg Michael; Langer Robert; Jia Xinqiao
Nanostructured materials for applications in drug delivery and tissue engineering.
Journal of biomaterials science. Polymer edition 2007;18(3):241-68.
2006: Luo Ying; Kobler James B; Zeitels Steven M; Langer Robert
Effects of growth factors on extracellular matrix production by vocal fold fibroblasts in 3-dimensional culture.
Tissue engineering 2006;12(12):3365-74.
2006: Jia Xinqiao; Yeo Yoon; Clifton Rodney J; Jiao Tong; Kohane Daniel S; Kobler James B; Zeitels Steven M; Langer Robert
Hyaluronic acid-based microgels and microgel networks for vocal fold regeneration.
Biomacromolecules 2006;7(12):3336-44.
2006: Bagalkot Vaishali; Farokhzad Omid C; Langer Robert; Jon Sangyong
An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform.
Angewandte Chemie (International ed. in English) 2006;45(48):8149-52.
2006: Khademhosseini Ali; Ferreira Lino; Blumling James; Yeh Judy; Karp Jeffrey M; Fukuda Junji; Langer Robert
Co-culture of human embryonic stem cells with murine embryonic fibroblasts on microwell-patterned substrates.
Biomaterials 2006;27(36):5968-77.
2006: Khademhosseini Ali; Eng George; Yeh Judy; Fukuda Junji; Blumling James; Langer Robert; Burdick Jason A
Micromolding of photocrosslinkable hyaluronic acid for cell encapsulation and entrapment.
Journal of biomedical materials research. Part A 2006;79(3):522-32.
2006: Yeh Judy; Ling Yibo; Karp Jeffrey M; Gantz Jay; Chandawarkar Akash; Eng George; Blumling James; Langer Robert; Khademhosseini Ali
Micromolding of shape-controlled, harvestable cell-laden hydrogels.
Biomaterials 2006;27(31):5391-8.
2006: Hofmann Sandra; Knecht Sven; Langer Robert; Kaplan David L; Vunjak-Novakovic Gordana; Merkle Hans P; Meinel Lorenz
Cartilage-like tissue engineering using silk scaffolds and mesenchymal stem cells.
Tissue engineering 2006;12(10):2729-38.
2006: Zugates Gregory T; Anderson Daniel G; Little Steven R; Lawhorn Ingrid E B; Langer Robert
Synthesis of poly(beta-amino ester)s with thiol-reactive side chains for DNA delivery.
Journal of the American Chemical Society 2006;128(39):12726-34.
2006: Fukuda Junji; Khademhosseini Ali; Yeo Yoon; Yang Xiaoyu; Yeh Judy; Eng George; Blumling James; Wang Chi-Fong; Kohane Daniel S; Langer Robert
Micromolding of photocrosslinkable chitosan hydrogel for spheroid microarray and co-cultures.
Biomaterials 2006;27(30):5259-67.
2006: Meinel Lorenz; Hofmann Sandra; Betz Oliver; Fajardo Robert; Merkle Hans P; Langer Robert; Evans Christopher H; Vunjak-Novakovic Gordana; Kaplan David L
Osteogenesis by human mesenchymal stem cells cultured on silk biomaterials: comparison of adenovirus mediated gene transfer and protein delivery of BMP-2.
Biomaterials 2006;27(28):4993-5002.
2006: Meinel L; Betz O; Fajardo R; Hofmann S; Nazarian A; Cory E; Hilbe M; McCool J; Langer R; Vunjak-Novakovic G; Merkle H P; Rechenberg B; Kaplan D L; Kirker-Head C
Silk based biomaterials to heal critical sized femur defects.
Bone 2006;39(4):922-31.
2006: Farokhzad Omid C; Dimitrakov Jordan D; Karp Jeffrey M; Khademhosseini Ali; Freeman Michael R; Langer Robert
Drug delivery systems in urology--getting "smarter".
Urology 2006;68(3):463-9.
2006: Green Jordan J; Shi Julie; Chiu Eugene; Leshchiner Elizaveta S; Langer Robert; Anderson Daniel G
Biodegradable polymeric vectors for gene delivery to human endothelial cells.
Bioconjugate chemistry 2006;17(5):1162-9.
2006: Berry David; Lynn David M; Berry Eric; Sasisekharan Ram; Langer Robert
Heparin localization and fine structure regulate Burkitt's lymphoma growth.
Biochemical and biophysical research communications 2006;348(3):850-6.
2006: Yeo Yoon; Highley Christopher B; Bellas Evangelia; Ito Taichi; Marini Robert; Langer Robert; Kohane Daniel S
In situ cross-linkable hyaluronic acid hydrogels prevent post-operative abdominal adhesions in a rabbit model.
Biomaterials 2006;27(27):4698-705.
2006: Yeo Yoon; Burdick Jason A; Highley Christopher B; Marini Robert; Langer Robert; Kohane Daniel S
Peritoneal application of chitosan and UV-cross-linkable chitosan.
Journal of biomedical materials research. Part A 2006;78(4):668-75.
2006: Radisic Milica; Park Hyoungshin; Chen Fen; Salazar-Lazzaro Johanna E; Wang Yadong; Dennis Robert; Langer Robert; Freed Lisa E; Vunjak-Novakovic Gordana
Biomimetic approach to cardiac tissue engineering: oxygen carriers and channeled scaffolds.
Tissue engineering 2006;12(8):2077-91.
2006: Suh Kahp Y; Khademhosseini Ali; Jon Sangyong; Langer Robert
Direct confinement of individual viruses within polyethylene glycol (PEG) nanowells.
Nano letters 2006;6(6):1196-201.
2006: Farokhzad Omid C; Karp Jeffrey M; Langer Robert
Nanoparticle-aptamer bioconjugates for cancer targeting.
Expert opinion on drug delivery 2006;3(3):311-24.
2006: Kohane Daniel S; Tse Julie Y; Yeo Yoon; Padera Robert; Shubina Maria; Langer Robert
Biodegradable polymeric microspheres and nanospheres for drug delivery in the peritoneum.
Journal of biomedical materials research. Part A 2006;77(2):351-61.
2006: Farokhzad Omid C; Cheng Jianjun; Teply Benjamin A; Sherifi Ines; Jon Sangyong; Kantoff Philip W; Richie Jerome P; Langer Robert
Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(16):6315-20.
2006: Hahn Mariah S; Kobler James B; Zeitels Steven M; Langer Robert
Quantitative and comparative studies of the vocal fold extracellular matrix II: collagen.
The Annals of otology, rhinology, and laryngology 2006;115(3):225-32.
2006: Chau Ying; Dang Natalie M; Tan Frederick E; Langer Robert
Investigation of targeting mechanism of new dextran-peptide-methotrexate conjugates using biodistribution study in matrix-metalloproteinase-overexpressing tumor xenograft model.
Journal of pharmaceutical sciences 2006;95(3):542-51.
2006: Fukuda Junji; Khademhosseini Ali; Yeh Judy; Eng George; Cheng Jianjun; Farokhzad Omid C; Langer Robert
Micropatterned cell co-cultures using layer-by-layer deposition of extracellular matrix components.
Biomaterials 2006;27(8):1479-86.
2006: Chau Ying; Padera Robert F; Dang Natalie M; Langer Robert
Antitumor efficacy of a novel polymer-peptide-drug conjugate in human tumor xenograft models.
International journal of cancer. Journal international du cancer 2006;118(6):1519-26.
2006: Hahn Mariah S; Teply Benjamin A; Stevens Molly M; Zeitels Steven M; Langer Robert
Collagen composite hydrogels for vocal fold lamina propria restoration.
Biomaterials 2006;27(7):1104-9.
2006: Hahn Mariah S; Kobler James B; Starcher Barry C; Zeitels Steven M; Langer Robert
Quantitative and comparative studies of the vocal fold extracellular matrix. I: Elastic fibers and hyaluronic acid.
The Annals of otology, rhinology, and laryngology 2006;115(2):156-64.
2006: Khademhosseini Ali; Langer Robert; Borenstein Jeffrey; Vacanti Joseph P
Microscale technologies for tissue engineering and biology.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(8):2480-7.
2006: Lee Philip J; Ahmad Naina; Langer Robert; Mitragotri Samir; Prasad Shastri V
Evaluation of chemical enhancers in the transdermal delivery of lidocaine.
International journal of pharmaceutics 2006;308(1-2):33-9.
2006: Radisic Milica; Malda Jos; Epping Eric; Geng Wenliang; Langer Robert; Vunjak-Novakovic Gordana
Oxygen gradients correlate with cell density and cell viability in engineered cardiac tissue.
Biotechnology and bioengineering 2006;93(2):332-43.
2006: Burdick Jason A; Ward Matthew; Liang Ellen; Young Michael J; Langer Robert
Stimulation of neurite outgrowth by neurotrophins delivered from degradable hydrogels.
Biomaterials 2006;27(3):452-9.
2006: Khademhosseini Ali; Bettinger Chris; Karp Jeffrey M; Yeh Judy; Ling Yibo; Borenstein Jeffrey; Fukuda Junji; Langer Robert
Interplay of biomaterials and micro-scale technologies for advancing biomedical applications.
Journal of biomaterials science. Polymer edition 2006;17(11):1221-40.
2006: Gerecht-Nir Sharon; Radisic Milica; Park Hyoungshin; Cannizzaro Christopher; Boublik Jan; Langer Robert; Vunjak-Novakovic Gordana
Biophysical regulation during cardiac development and application to tissue engineering.
The International journal of developmental biology 2006;50(2-3):233-43.
2005: Khademhosseini Ali; Yeh Judy; Eng George; Karp Jeffrey; Kaji Hirokazu; Borenstein Jeffrey; Farokhzad Omid C; Langer Robert
Cell docking inside microwells within reversibly sealed microfluidic channels for fabricating multiphenotype cell arrays.
Lab on a chip 2005;5(12):1380-6.
2005: Stevens Molly M; Mayer Michael; Anderson Daniel G; Weibel Douglas B; Whitesides George M; Langer Robert
Direct patterning of mammalian cells onto porous tissue engineering substrates using agarose stamps.
Biomaterials 2005;26(36):7636-41.
2005: Tomita Minoru; Lavik Erin; Klassen Henry; Zahir Tasneem; Langer Robert; Young Michael J
Biodegradable polymer composite grafts promote the survival and differentiation of retinal progenitor cells.
Stem cells (Dayton, Ohio) 2005;23(10):1579-88.
2005: Pfeifer Blaine A; Burdick Jason A; Little Steve R; Langer Robert
Poly(ester-anhydride):poly(beta-amino ester) micro- and nanospheres: DNA encapsulation and cellular transfection.
International journal of pharmaceutics 2005;304(1-2):210-9.
2005: Meinel Lorenz; Fajardo Robert; Hofmann Sandra; Langer Robert; Chen Jake; Snyder Brian; Vunjak-Novakovic Gordana; Kaplan David
Silk implants for the healing of critical size bone defects.
Bone 2005;37(5):688-98.
2005: Warfvinge Karin; Kiilgaard Jens F; Lavik Erin B; Scherfig Erik; Langer Robert; Klassen Henry J; Young Michael J
Retinal progenitor cell xenografts to the pig retina: morphologic integration and cytochemical differentiation.
Archives of ophthalmology 2005;123(10):1385-93.
2005: Wood Kris C; Little Steven R; Langer Robert; Hammond Paula T
A family of hierarchically self-assembling linear-dendritic hybrid polymers for highly efficient targeted gene delivery.
Angewandte Chemie (International ed. in English) 2005;44(41):6704-8.
2005: Little Steven R; Lynn David M; Puram Sidharth V; Langer Robert
Formulation and characterization of poly (beta amino ester) microparticles for genetic vaccine delivery.
Journal of controlled release : official journal of the Controlled Release Society 2005;107(3):449-62.
2005: Yeo Yoon; Bellas Evangelia; Firestone William; Langer Robert; Kohane Daniel S
Complex coacervates for thermally sensitive controlled release of flavor compounds.
Journal of agricultural and food chemistry 2005;53(19):7518-25.
2005: Farokhzad Omid C; Khademhosseini Ali; Jon Sangyong; Hermmann Aurelia; Cheng Jianjun; Chin Curtis; Kiselyuk Alice; Teply Benjamin; Eng George; Langer Robert
Microfluidic system for studying the interaction of nanoparticles and microparticles with cells.
Analytical chemistry 2005;77(17):5453-9.
2005: Li Yawen; Ho Duc Hong Linh; Tyler Betty; Williams Tiffany; Tupper Malinda; Langer Robert; Brem Henry; Cima Michael J
In vivo delivery of BCNU from a MEMS device to a tumor model.
Journal of controlled release : official journal of the Controlled Release Society 2005;106(1-2):138-45.
2005: Stevens Molly M; Marini Robert P; Schaefer Dirk; Aronson Joshua; Langer Robert; Shastri V Prasad
In vivo engineering of organs: the bone bioreactor.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(32):11450-5.
2005: Anderson Daniel G; Putnam David; Lavik Erin B; Mahmood Tahir A; Langer Robert
Biomaterial microarrays: rapid, microscale screening of polymer-cell interaction.
Biomaterials 2005;26(23):4892-7.
2005: Levenberg Shulamit; Rouwkema Jeroen; Macdonald Mara; Garfein Evan S; Kohane Daniel S; Darland Diane C; Marini Robert; van Blitterswijk Clemens A; Mulligan Richard C; D'Amore Patricia A; Langer Robert
Engineering vascularized skeletal muscle tissue.
Nature biotechnology 2005;23(7):879-84.
2005: Hahn Mariah S; Kobler James B; Zeitels Steven M; Langer Robert
Midmembranous vocal fold lamina propria proteoglycans across selected species.
The Annals of otology, rhinology, and laryngology 2005;114(6):451-62.
2005: George Paul M; Lyckman Alvin W; LaVan David A; Hegde Anita; Leung Yuika; Avasare Rupali; Testa Chris; Alexander Phillip M; Langer Robert; Sur Mriganka
Fabrication and biocompatibility of polypyrrole implants suitable for neural prosthetics.
Biomaterials 2005;26(17):3511-9.
2005: Lavik E B; Klassen H; Warfvinge K; Langer R; Young M J
Fabrication of degradable polymer scaffolds to direct the integration and differentiation of retinal progenitors.
Biomaterials 2005;26(16):3187-96.
2005: Grayson Amy C Richards; Cima Michael J; Langer Robert
Size and temperature effects on poly(lactic-co-glycolic acid) degradation and microreservoir device performance.
Biomaterials 2005;26(14):2137-45.
2005: Akinc Akin; Thomas Mini; Klibanov Alexander M; Langer Robert
Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis.
The journal of gene medicine 2005;7(5):657-63.
2005: Lee Philip J; Langer Robert; Shastri V Prasad
Role of n-methyl pyrrolidone in the enhancement of aqueous phase transdermal transport.
Journal of pharmaceutical sciences 2005;94(4):912-7.
2005: Levenberg Shulamit; Burdick Jason A; Kraehenbuehl Thomas; Langer Robert
Neurotrophin-induced differentiation of human embryonic stem cells on three-dimensional polymeric scaffolds.
Tissue engineering 2005;11(3-4):506-12.
2005: Anderson Daniel G; Akinc Akin; Hossain Naushad; Langer Robert
Structure/property studies of polymeric gene delivery using a library of poly(beta-amino esters).
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(3):426-34.
2005: Radisic Milica; Deen William; Langer Robert; Vunjak-Novakovic Gordana
Mathematical model of oxygen distribution in engineered cardiac tissue with parallel channel array perfused with culture medium containing oxygen carriers.
American journal of physiology. Heart and circulatory physiology 2005;288(3):H1278-89.
2005: Suh Kahp Y; Yang Jen Ming; Khademhosseini Ali; Berry David; Tran Thanh-Nga T; Park Hyongshin; Langer Robert
Characterization of chemisorbed hyaluronic acid directly immobilized on solid substrates.
Journal of biomedical materials research. Part B, Applied biomaterials 2005;72(2):292-8.
2005: LaVan David A; Padera Robert F; Friedmann Thomas A; Sullivan John P; Langer Robert; Kohane Daniel S
In vivo evaluation of tetrahedral amorphous carbon.
Biomaterials 2005;26(5):465-73.
2005: Fidkowski Christina; Kaazempur-Mofrad Mohammad R; Borenstein Jeffrey; Vacanti Joseph P; Langer Robert; Wang Yadong
Endothelialized microvasculature based on a biodegradable elastomer.
Tissue engineering 2005;11(1-2):302-9.
2005: Burdick Jason A; Chung Cindy; Jia Xinqiao; Randolph Mark A; Langer Robert
Controlled degradation and mechanical behavior of photopolymerized hyaluronic acid networks.
Biomacromolecules 2005;6(1):386-91.
2005: Meinel Lorenz; Hofmann Sandra; Karageorgiou Vassilis; Kirker-Head Carl; McCool John; Gronowicz Gloria; Zichner Ludwig; Langer Robert; Vunjak-Novakovic Gordana; Kaplan David L
The inflammatory responses to silk films in vitro and in vivo.
Biomaterials 2005;26(2):147-55.
2005: Pfeifer Blaine A; Burdick Jason A; Langer Robert
Formulation and surface modification of poly(ester-anhydride) micro- and nanospheres.
Biomaterials 2005;26(2):117-24.
2005: Little Steven R; Langer Robert
Nonviral delivery of cancer genetic vaccines.
Advances in biochemical engineering/biotechnology 2005;99():93-118.
2004: Radisic Milica; Park Hyoungshin; Shing Helen; Consi Thomas; Schoen Frederick J; Langer Robert; Freed Lisa E; Vunjak-Novakovic Gordana
Functional assembly of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(52):18129-34.
2004: Shawgo Rebecca S; Voskerician Gabriela; Duc Hong Linh Ho; Li Yawen; Lynn Aaron; MacEwan Matthew; Langer Robert; Anderson James M; Cima Michael J
Repeated in vivo electrochemical activation and the biological effects of microelectromechanical systems drug delivery device.
Journal of biomedical materials research. Part A 2004;71(4):559-68.
2004: Li Yawen; Shawgo Rebecca S; Tyler Betty; Henderson Paul T; Vogel John S; Rosenberg Aron; Storm Phillip B; Langer Robert; Brem Henry; Cima Michael J
In vivo release from a drug delivery MEMS device.
Journal of controlled release : official journal of the Controlled Release Society 2004;100(2):211-9.
2004: Anderson Daniel G; Peng Weidan; Akinc Akin; Hossain Naushad; Kohn Anat; Padera Robert; Langer Robert; Sawicki Janet A
A polymer library approach to suicide gene therapy for cancer.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(45):16028-33.
2004: Farokhzad Omid C; Jon Sangyong; Khademhosseini Ali; Tran Thanh-Nga T; Lavan David A; Langer Robert
Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells.
Cancer research 2004;64(21):7668-72.
2004: Meinel Lorenz; Hofmann Sandra; Karageorgiou Vassilis; Zichner Ludwig; Langer Robert; Kaplan David; Vunjak-Novakovic Gordana
Engineering cartilage-like tissue using human mesenchymal stem cells and silk protein scaffolds.
Biotechnology and bioengineering 2004;88(3):379-91.
2004: Kushner Joseph; Blankschtein Daniel; Langer Robert
Experimental demonstration of the existence of highly permeable localized transport regions in low-frequency sonophoresis.
Journal of pharmaceutical sciences 2004;93(11):2733-45.
2004: Khademhosseini Ali; Yeh Judy; Jon Sangyong; Eng George; Suh Kahp Y; Burdick Jason A; Langer Robert
Molded polyethylene glycol microstructures for capturing cells within microfluidic channels.
Lab on a chip 2004;4(5):425-30.
2004: Meinel Lorenz; Karageorgiou Vassilis; Hofmann Sandra; Fajardo Robert; Snyder Brian; Li Chunmei; Zichner Ludwig; Langer Robert; Vunjak-Novakovic Gordana; Kaplan David L
Engineering bone-like tissue in vitro using human bone marrow stem cells and silk scaffolds.
Journal of biomedical materials research. Part A 2004;71(1):25-34.
2004: Anderson Daniel G; Burdick Jason A; Langer Robert
Materials science. Smart biomaterials.
Science (New York, N.Y.) 2004;305(5692):1923-4.
2004: Suh Kahp Y; Khademhosseini Ali; Yoo Pil J; Langer Robert
Patterning and separating infected bacteria using host-parasite and virus-antibody interactions.
Biomedical microdevices 2004;6(3):223-9.
2004: Stevens Molly M; Marini Robert P; Martin Ivan; Langer Robert; Prasad Shastri V
FGF-2 enhances TGF-beta1-induced periosteal chondrogenesis.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2004;22(5):1114-9.
2004: Haining W Nicholas; Anderson Daniel G; Little Steven R; von Bergwelt-Baildon Michael S; Cardoso Angelo A; Alves Pedro; Kosmatopoulos Kostas; Nadler Lee M; Langer Robert; Kohane Daniel S;
pH-triggered microparticles for peptide vaccination.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(4):2578-85.
2004: Jia Xinqiao; Colombo Gaia; Padera Robert; Langer Robert; Kohane Daniel S
Prolongation of sciatic nerve blockade by in situ cross-linked hyaluronic acid.
Biomaterials 2004;25(19):4797-804.
2004: Khademhosseini Ali; Suh Kahp Y; Yang Jen M; Eng George; Yeh Judy; Levenberg Shulamit; Langer Robert
Layer-by-layer deposition of hyaluronic acid and poly-L-lysine for patterned cell co-cultures.
Biomaterials 2004;25(17):3583-92.
2004: Marini Robert P; Stevens Molly M; Langer Robert; Shastri V Prasad
Hydraulic elevation of the periosteum: a novel technique for periosteal harvest.
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2004;17(4):229-33.
2004: Chau Ying; Tan Frederick E; Langer Robert
Synthesis and characterization of dextran-peptide-methotrexate conjugates for tumor targeting via mediation by matrix metalloproteinase II and matrix metalloproteinase IX.
Bioconjugate chemistry 2004;15(4):931-41.
2004: Suh Kahp Y; Khademhosseini Ali; Eng George; Langer Robert
Single nanocrystal arrays on patterned poly(ethylene glycol) copolymer microstructures using selective wetting and drying.
Langmuir : the ACS journal of surfaces and colloids 2004;20(15):6080-4.
2004: Khademhosseini Ali; Suh Kahp Y; Jon Sangyong; Eng George; Yeh Judy; Chen Guan-Jong; Langer Robert
A soft lithographic approach to fabricate patterned microfluidic channels.
Analytical chemistry 2004;76(13):3675-81.
2004: Lavik E; Langer R
Tissue engineering: current state and perspectives.
Applied microbiology and biotechnology 2004;65(1):1-8.
2004: Anderson Daniel G; Levenberg Shulamit; Langer Robert
Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells.
Nature biotechnology 2004;22(7):863-6.
2004: Qi Yiwei; Zhao Ganlin; Liu Dongfang; Shriver Zachary; Sundaram Mallik; Sengupta Shiladitya; Venkataraman Ganesh; Langer Robert; Sasisekharan Ram
Delivery of therapeutic levels of heparin and low-molecular-weight heparin through a pulmonary route.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(26):9867-72.
2004: Little Steven R; Lynn David M; Ge Qing; Anderson Daniel G; Puram Sidharth V; Chen Jianzhu; Eisen Herman N; Langer Robert
Poly-beta amino ester-containing microparticles enhance the activity of nonviral genetic vaccines.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(26):9534-9.
2004: Richards Grayson Amy C; Cima Michael J; Langer Robert
Molecular release from a polymeric microreservoir device: Influence of chemistry, polymer swelling, and loading on device performance.
Journal of biomedical materials research. Part A 2004;69(3):502-12.
2004: Berry David; Lynn David M; Sasisekharan Ram; Langer Robert
Poly(beta-amino ester)s promote cellular uptake of heparin and cancer cell death.
Chemistry & biology 2004;11(4):487-98.
2004: Voskerician Gabriela; Shawgo Rebecca S; Hiltner P Anne; Anderson James M; Cima Michael J; Langer Robert
In vivo inflammatory and wound healing effects of gold electrode voltammetry for MEMS micro-reservoir drug delivery device.
IEEE transactions on bio-medical engineering 2004;51(4):627-35.
2004: Langer Robert; Tirrell David A
Designing materials for biology and medicine.
Nature 2004;428(6982):487-92.
2004: Wang Chun; Ge Qing; Ting David; Nguyen David; Shen Hui-Rong; Chen Jianzhu; Eisen Herman N; Heller Jorge; Langer Robert; Putnam David
Molecularly engineered poly(ortho ester) microspheres for enhanced delivery of DNA vaccines.
Nature materials 2004;3(3):190-6.
2004: Prausnitz Mark R; Mitragotri Samir; Langer Robert
Current status and future potential of transdermal drug delivery.
Nature reviews. Drug discovery 2004;3(2):115-24.
2004: Stevens Molly M; Qanadilo Hala F; Langer Robert; Prasad Shastri V
A rapid-curing alginate gel system: utility in periosteum-derived cartilage tissue engineering.
Biomaterials 2004;25(5):887-94.
2004: Shastri Venkatram Prasad; Padera Robert F; Tarcha Peter; Langer Robert
A preliminary report on the biocompatibility of photopolymerizable semi-interpenetrating anhydride networks.
Biomaterials 2004;25(4):715-21.
2004: Suh Kahp Y; Seong Jiehyun; Khademhosseini Ali; Laibinis Paul E; Langer Robert
A simple soft lithographic route to fabrication of poly(ethylene glycol) microstructures for protein and cell patterning.
Biomaterials 2004;25(3):557-63.
2004: Radisic Milica; Yang Liming; Boublik Jan; Cohen Richard J; Langer Robert; Freed Lisa E; Vunjak-Novakovic Gordana
Medium perfusion enables engineering of compact and contractile cardiac tissue.
American journal of physiology. Heart and circulatory physiology 2004;286(2):H507-16.
2004: Pouliot Roxane; Azhari Rosa; Qanadilo Hala F; Mahmood Tahir A; Triantafyllou Michael S; Langer Robert
Tissue engineering of fish skin: behavior of fish cells on poly(ethylene glycol terephthalate)/poly(butylene terephthalate) copolymers in relation to the composition of the polymer substrate as an initial step in constructing a robotic/living tissue hybrid.
Tissue engineering 2004;10(1-2):7-21.
2004: Meinel Lorenz; Karageorgiou Vassilis; Fajardo Robert; Snyder Brian; Shinde-Patil Vivek; Zichner Ludwig; Kaplan David; Langer Robert; Vunjak-Novakovic Gordana
Bone tissue engineering using human mesenchymal stem cells: effects of scaffold material and medium flow.
Annals of biomedical engineering 2004;32(1):112-22.
2004: Grayson Amy C R; Voskerician Gabriela; Lynn Aaron; Anderson James M; Cima Michael J; Langer Robert
Differential degradation rates in vivo and in vitro of biocompatible poly(lactic acid) and poly(glycolic acid) homo- and co-polymers for a polymeric drug-delivery microchip.
Journal of biomaterials science. Polymer edition 2004;15(10):1281-304.
2004: Levenberg Shulamit; Langer Robert
Advances in tissue engineering.
Current topics in developmental biology 2004;61():113-34.
2004: Seidel J O; Pei M; Gray M L; Langer R; Freed L E; Vunjak-Novakovic G
Long-term culture of tissue engineered cartilage in a perfused chamber with mechanical stimulation.
Biorheology 2004;41(3-4):445-58.
2003: Yu Betty; Kim Ki Hean; So Peter T C; Blankschtein Daniel; Langer Robert
Evaluation of fluorescent probe surface intensities as an indicator of transdermal permeant distributions using wide-area two-photon fluorescence microscopy.
Journal of pharmaceutical sciences 2003;92(12):2354-65.
2003: Richards Grayson Amy C; Choi Insung S; Tyler Betty M; Wang Paul P; Brem Henry; Cima Michael J; Langer Robert
Multi-pulse drug delivery from a resorbable polymeric microchip device.
Nature materials 2003;2(11):767-72.
2003: Jon Sangyong; Anderson Daniel G; Langer Robert
Degradable poly(amino alcohol esters) as potential DNA vectors with low cytotoxicity.
Biomacromolecules 2003;4(6):1759-62.
2003: Putnam David; Zelikin Alexander N; Izumrudov Vladimir A; Langer Robert
Polyhistidine-PEG:DNA nanocomposites for gene delivery.
Biomaterials 2003;24(24):4425-33.
2003: Kohane Daniel S; Anderson Daniel G; Yu Christine; Langer Robert
pH-triggered release of macromolecules from spray-dried polymethacrylate microparticles.
Pharmaceutical research 2003;20(10):1533-8.
2003: Levenberg Shulamit; Huang Ngan F; Lavik Erin; Rogers Arlin B; Itskovitz-Eldor Joseph; Langer Robert
Differentiation of human embryonic stem cells on three-dimensional polymer scaffolds.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(22):12741-6.
2003: LaVan David A; McGuire Terry; Langer Robert
Small-scale systems for in vivo drug delivery.
Nature biotechnology 2003;21(10):1184-91.
2003: Akinc Akin; Anderson Daniel G; Lynn David M; Langer Robert
Synthesis of poly(beta-amino ester)s optimized for highly effective gene delivery.
Bioconjugate chemistry 2003;14(5):979-88.
2003: Shastri Venkatram Prasad; Hildgen Patrice; Langer Robert
In situ pore formation in a polymer matrix by differential polymer degradation.
Biomaterials 2003;24(18):3133-7.
2003: Fu Karen; Harrell Roy; Zinski Kim; Um Christina; Jaklenec Ana; Frazier Jan; Lotan Noah; Burke Paul; Klibanov Alexander M; Langer Robert
A potential approach for decreasing the burst effect of protein from PLGA microspheres.
Journal of pharmaceutical sciences 2003;92(8):1582-91.
2003: Anderson Daniel G; Lynn David M; Langer Robert
Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery.
Angewandte Chemie (International ed. in English) 2003;42(27):3153-8.
2003: Kohane Daniel S; Smith Sarah E; Louis David N; Colombo Gaia; Ghoroghchian Peter; Hunfeld Nicole G M; Berde Charles B; Langer Robert
Prolonged duration local anesthesia from tetrodotoxin-enhanced local anesthetic microspheres.
Pain 2003;104(1-2):415-21.
2003: Wang Yadong; Kim Yu Mi; Langer Robert
In vivo degradation characteristics of poly(glycerol sebacate).
Journal of biomedical materials research. Part A 2003;66(1):192-7.
2003: Nashat Amir H; Langer Robert
Temporal characteristics of activation, deactivation, and restimulation of signal transduction following depolarization in the pheochromocytoma cell line PC12.
Molecular and cellular biology 2003;23(14):4788-95.
2003: Baroli Bianca; Shastri Venkatram Prasad; Langer Robert
A method to protect sensitive molecules from a light-induced polymerizing environment.
Journal of pharmaceutical sciences 2003;92(6):1186-95.
2003: Akinc Akin; Lynn David M; Anderson Daniel G; Langer Robert
Parallel synthesis and biophysical characterization of a degradable polymer library for gene delivery.
Journal of the American Chemical Society 2003;125(18):5316-23.
2003: Lahann Jörg; Balcells Mercedes; Lu Hang; Rodon Teresa; Jensen Klavs F; Langer Robert
Reactive polymer coatings: a first step toward surface engineering of microfluidic devices.
Analytical chemistry 2003;75(9):2117-22.
2003: Radisic Milica; Euloth Michelle; Yang Liming; Langer Robert; Freed Lisa E; Vunjak-Novakovic Gordana
High-density seeding of myocyte cells for cardiac tissue engineering.
Biotechnology and bioengineering 2003;82(4):403-14.
2003: Voskerician Gabriela; Shive Matthew S; Shawgo Rebecca S; von Recum Horst; Anderson James M; Cima Michael J; Langer Robert
Biocompatibility and biofouling of MEMS drug delivery devices.
Biomaterials 2003;24(11):1959-67.
2003: LaVan David A; George Paul M; Langer Robert
Simple, three-dimensional microfabrication of electrodeposited structures.
Angewandte Chemie (International ed. in English) 2003;42(11):1262-5.
2003: Yu Betty; Kim Ki Hean; So Peter T C; Blankschtein Daniel; Langer Robert
Visualization of oleic acid-induced transdermal diffusion pathways using two-photon fluorescence microscopy.
The Journal of investigative dermatology 2003;120(3):448-55.
2003: Lee Philp J; Langer Robert; Shastri V Prasad
Novel microemulsion enhancer formulation for simultaneous transdermal delivery of hydrophilic and hydrophobic drugs.
Pharmaceutical research 2003;20(2):264-9.
2003: Lahann Joerg; Mitragotri Samir; Tran Thanh-Nga; Kaido Hiroki; Sundaram Jagannathan; Choi Insung S; Hoffer Saskia; Somorjai Gabor A; Langer Robert
A reversibly switching surface.
Science (New York, N.Y.) 2003;299(5605):371-4.
2003: Sundaram Mallik; Qi Yiwei; Shriver Zachary; Liu Dongfang; Zhao Ganlin; Venkataraman Ganesh; Langer Robert; Sasisekharan Ram
Rational design of low-molecular weight heparins with improved in vivo activity.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(2):651-6.
2003: Valente André X C N; Langer Robert; Stone Howard A; Edwards David A
Recent advances in the development of an inhaled insulin product.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2003;17(1):9-17.
2002: Madry Henning; Padera Robert; Seidel Joachim; Langer Robert; Freed Lisa E; Trippel Stephen B; Vunjak-Novakovic Gordana
Gene transfer of a human insulin-like growth factor I cDNA enhances tissue engineering of cartilage.
Human gene therapy 2002;13(13):1621-30.
2002: Tang Hua; Wang Chiao Chun Joanne; Blankschtein Daniel; Langer Robert
An investigation of the role of cavitation in low-frequency ultrasound-mediated transdermal drug transport.
Pharmaceutical research 2002;19(8):1160-9.
2002: Rupnick Maria A; Panigrahy Dipak; Zhang Chen-Yu; Dallabrida Susan M; Lowell Bradford B; Langer Robert; Folkman M Judah
Adipose tissue mass can be regulated through the vasculature.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10730-5.
2002: Kohane Daniel S; Plesnila Nikolaus; Thomas Sunu S; Le Dean; Langer Robert; Moskowitz Michael A
Lipid-sugar particles for intracranial drug delivery: safety and biocompatibility.
Brain research 2002;946(2):206-13.
2002: Tang Hua; Blankschtein Daniel; Langer Robert
Prediction of steady-state skin permeabilities of polar and nonpolar permeants across excised pig skin based on measurements of transient diffusion: characterization of hydration effects on the skin porous pathway.
Journal of pharmaceutical sciences 2002;91(8):1891-907.
2002: Tang Hua; Blankschtein Daniel; Langer Robert
Effects of low-frequency ultrasound on the transdermal permeation of mannitol: comparative studies with in vivo and in vitro skin.
Journal of pharmaceutical sciences 2002;91(8):1776-94.
2002: Akinc Akin; Langer Robert
Measuring the pH environment of DNA delivered using nonviral vectors: implications for lysosomal trafficking.
Biotechnology and bioengineering 2002;78(5):503-8.
2002: Yu Betty; Hean Kim Ki; So Peter T C; Blankschtein Daniel; Langer Robert
Topographic heterogeneity in transdermal transport revealed by high-speed two-photon microscopy: determination of representative skin sample sizes.
The Journal of investigative dermatology 2002;118(6):1085-8.
2002: Wang Yadong; Ameer Guillermo A; Sheppard Barbara J; Langer Robert
A tough biodegradable elastomer.
Nature biotechnology 2002;20(6):602-6.
2002: Carrier Rebecca L; Rupnick Maria; Langer Robert; Schoen Frederick J; Freed Lisa E; Vunjak-Novakovic Gordana
Effects of oxygen on engineered cardiac muscle.
Biotechnology and bioengineering 2002;78(6):617-25.
2002: Zelikin Alexander N; Putnam David; Shastri Prasad; Langer Robert; Izumrudov Vladimir A
Aliphatic ionenes as gene delivery agents: elucidation of structure-function relationship through modification of charge density and polymer length.
Bioconjugate chemistry 2002;13(3):548-53.
2002: Carrier Rebecca L; Rupnick Maria; Langer Robert; Schoen Frederick J; Freed Lisa E; Vunjak-Novakovic Gordana
Perfusion improves tissue architecture of engineered cardiac muscle.
Tissue engineering 2002;8(2):175-88.
2002: Levenberg Shulamit; Golub Justin S; Amit Michal; Itskovitz-Eldor Joseph; Langer Robert
Endothelial cells derived from human embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4391-6.
2002: Terahara Takaaki; Mitragotri Samir; Langer Robert
Porous resins as a cavitation enhancer for low-frequency sonophoresis.
Journal of pharmaceutical sciences 2002;91(3):753-9.
2002: Terahara T; Mitragotri S; Kost J; Langer R
Dependence of low-frequency sonophoresis on ultrasound parameters; distance of the horn and intensity.
International journal of pharmaceutics 2002;235(1-2):35-42.
2002: Teng Yang D; Lavik Erin B; Qu Xianlu; Park Kook I; Ourednik Jitka; Zurakowski David; Langer Robert; Snyder Evan Y
Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3024-9.
2002: Kohane Daniel S; Lipp Michael; Kinney Ramsey C; Anthony Douglas C; Louis David N; Lotan Noah; Langer Robert
Biocompatibility of lipid-protein-sugar particles containing bupivacaine in the epineurium.
Journal of biomedical materials research 2002;59(3):450-9.
2002: Blunk Torsten; Sieminski Alisha L; Gooch Keith J; Courter Donald L; Hollander Anthony P; Nahir A Menahem; Langer Robert; Vunjak-Novakovic Gordana; Freed Lisa E
Differential effects of growth factors on tissue-engineered cartilage.
Tissue engineering 2002;8(1):73-84.
2002: Zelikin Alexander N; Lynn David M; Farhadi Jian; Martin Ivan; Shastri Venkatram; Langer Robert
Erodible conducting polymers for potential biomedical applications.
Angewandte Chemie (International ed. in English) 2002;41(1):141-4.
2002: LaVan David A; Lynn David M; Langer Robert
Moving smaller in drug discovery and delivery.
Nature reviews. Drug discovery 2002;1(1):77-84.
2002: Ameer G A; Mahmood T A; Langer R
A biodegradable composite scaffold for cell transplantation.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2002;20(1):16-9.
2002: Lavik Erin; Teng Yang D; Snyder Evan; Langer Robert
Seeding neural stem cells on scaffolds of PGA, PLA, and their copolymers.
Methods in molecular biology (Clifton, N.J.) 2002;198():89-97.
2001: Elisseeff J; McIntosh W; Fu K; Blunk B T; Langer R
Controlled-release of IGF-I and TGF-beta1 in a photopolymerizing hydrogel for cartilage tissue engineering.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2001;19(6):1098-104.
2001: Choi W S; Murthy G G; Edwards D A; Langer R; Klibanov A M
Inhalation delivery of proteins from ethanol suspensions.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11103-7.
2001: Ameer G A; Crumpler E T; Langer R
Cell-killing potential of a water-soluble radical initiator.
International journal of cancer. Journal international du cancer 2001;93(6):875-9.
2001: Lynn D M; Anderson D G; Putnam D; Langer R
Accelerated discovery of synthetic transfection vectors: parallel synthesis and screening of a degradable polymer library.
Journal of the American Chemical Society 2001;123(33):8155-6.
2001: Perez C; Sanchez A; Putnam D; Ting D; Langer R; Alonso M J
Poly(lactic acid)-poly(ethylene glycol) nanoparticles as new carriers for the delivery of plasmid DNA.
Journal of controlled release : official journal of the Controlled Release Society 2001;75(1-2):211-24.
2001: Yu B; Dong C Y; So P T; Blankschtein D; Langer R
In vitro visualization and quantification of oleic acid induced changes in transdermal transport using two-photon fluorescence microscopy.
The Journal of investigative dermatology 2001;117(1):16-25.
2001: Langer R
Drug delivery. Drugs on target.
Science (New York, N.Y.) 2001;293(5527):58-9.
2001: Lavik E B; Hrkach J S; Lotan N; Nazarov R; Langer R
A simple synthetic route to the formation of a block copolymer of poly(lactic-co-glycolic acid) and polylysine for the fabrication of functionalized, degradable structures for biomedical applications.
Journal of biomedical materials research 2001;58(3):291-4.
2001: Tang H; Mitragotri S; Blankschtein D; Langer R
Theoretical description of transdermal transport of hydrophilic permeants: application to low-frequency sonophoresis.
Journal of pharmaceutical sciences 2001;90(5):545-68.
2001: Martin I; Shastri V P; Padera R F; Yang J; Mackay A J; Langer R; Vunjak-Novakovic G; Freed L E
Selective differentiation of mammalian bone marrow stromal cells cultured on three-dimensional polymer foams.
Journal of biomedical materials research 2001;55(2):229-35.
2001: Ameer G A; Grovender E A; Ploegh H; Ting D; Owen W F; Rupnick M; Langer R
A novel immunoadsorption device for removing beta2-microglobulin from whole blood.
Kidney international 2001;59(4):1544-50.
2001: Hirosue S; Müller B G; Mulligan R C; Langer R
Plasmid DNA encapsulation and release from solvent diffusion nanospheres.
Journal of controlled release : official journal of the Controlled Release Society 2001;70(1-2):231-42.
2001: Putnam D; Gentry C A; Pack D W; Langer R
Polymer-based gene delivery with low cytotoxicity by a unique balance of side-chain termini.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(3):1200-5.
2001: Papadaki M; Bursac N; Langer R; Merok J; Vunjak-Novakovic G; Freed L E
Tissue engineering of functional cardiac muscle: molecular, structural, and electrophysiological studies.
American journal of physiology. Heart and circulatory physiology 2001;280(1):H168-78.
2001: Papadaki M; Mahmood T; Gupta P; Claase M B; Grijpma D W; Riesle J; van Blitterswijk C A; Langer R
The different behaviors of skeletal muscle cells and chondrocytes on PEGT/PBT block copolymers are related to the surface properties of the substrate.
Journal of biomedical materials research 2001;54(1):47-58.
2000: Schaefer D; Martin I; Shastri P; Padera R F; Langer R; Freed L E; Vunjak-Novakovic G
In vitro generation of osteochondral composites.
Biomaterials 2000;21(24):2599-606.
2000: Kohane D S; Lipp M; Kinney R C; Lotan N; Langer R
Sciatic nerve blockade with lipid-protein-sugar particles containing bupivacaine.
Pharmaceutical research 2000;17(10):1243-9.
2000: Mitragotri S; Coleman M; Kost J; Langer R
Analysis of ultrasonically extracted interstitial fluid as a predictor of blood glucose levels.
Journal of applied physiology (Bethesda, Md. : 1985) 2000;89(3):961-6.
2000: Elisseeff J; McIntosh W; Anseth K; Riley S; Ragan P; Langer R
Photoencapsulation of chondrocytes in poly(ethylene oxide)-based semi-interpenetrating networks.
Journal of biomedical materials research 2000;51(2):164-71.
2000: Mitragotri S; Ray D; Farrell J; Tang H; Yu B; Kost J; Blankschtein D; Langer R
Synergistic effect of low-frequency ultrasound and sodium lauryl sulfate on transdermal transport.
Journal of pharmaceutical sciences 2000;89(7):892-900.
2000: Mitragotri S; Coleman M; Kost J; Langer R
Transdermal extraction of analytes using low-frequency ultrasound.
Pharmaceutical research 2000;17(4):466-70.
2000: Shastri V P; Martin I; Langer R
Macroporous polymer foams by hydrocarbon templating.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(5):1970-5.
2000: Langer R
Biomaterials in drug delivery and tissue engineering: one laboratory's experience.
Accounts of chemical research 2000;33(2):94-101.
2000: Kim B S; Hrkach J S; Langer R
Biodegradable photo-crosslinked poly(ether-ester) networks for lubricious coatings.
Biomaterials 2000;21(3):259-65.
2000: Langer R
Tissue engineering.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;1(1):12-5.
2000: Fu K; Pack D W; Klibanov A M; Langer R
Visual evidence of acidic environment within degrading poly(lactic-co-glycolic acid) (PLGA) microspheres.
Pharmaceutical research 2000;17(1):100-6.
2000: Mitragotri S; Farrell J; Tang H; Terahara T; Kost J; Langer R
Determination of threshold energy dose for ultrasound-induced transdermal drug transport.
Journal of controlled release : official journal of the Controlled Release Society 2000;63(1-2):41-52.
2000: Pack D W; Putnam D; Langer R
Design of imidazole-containing endosomolytic biopolymers for gene delivery.
Biotechnology and bioengineering 2000;67(2):217-23.
2000: Martin I; Obradovic B; Treppo S; Grodzinsky A J; Langer R; Freed L E; Vunjak-Novakovic G
Modulation of the mechanical properties of tissue engineered cartilage.
Biorheology 2000;37(1-2):141-7.
2000: Patel N; Bhandari R; Shakesheff K M; Cannizzaro S M; Davies M C; Langer R; Roberts C J; Tendler S J; Williams P M
Printing patterns of biospecifically-adsorbed protein.
Journal of biomaterials science. Polymer edition 2000;11(3):319-31.
1999: Martin I; Vunjak-Novakovic G; Yang J; Langer R; Freed L E
Mammalian chondrocytes expanded in the presence of fibroblast growth factor 2 maintain the ability to differentiate and regenerate three-dimensional cartilaginous tissue.
Experimental cell research 1999;253(2):681-8.
1999: Vanbever R; Mintzes J D; Wang J; Nice J; Chen D; Batycky R; Langer R; Edwards D A
Formulation and physical characterization of large porous particles for inhalation.
Pharmaceutical research 1999;16(11):1735-42.
1999: Tobío M; Schwendeman S P; Guo Y; McIver J; Langer R; Alonso M J
Improved immunogenicity of a core-coated tetanus toxoid delivery system.
Vaccine 1999;18(7-8):618-22.
1999: Zewert T E; Pliquett U F; Vanbever R; Langer R; Weaver J C
Creation of transdermal pathways for macromolecule transport by skin electroporation and a low toxicity, pathway-enlarging molecule.
Bioelectrochemistry and bioenergetics (Lausanne, Switzerland) 1999;49(1):11-20.
1999: Elisseeff J; Anseth K; Sims D; McIntosh W; Randolph M; Yaremchuk M; Langer R
Transdermal photopolymerization of poly(ethylene oxide)-based injectable hydrogels for tissue-engineered cartilage.
Plastic and reconstructive surgery 1999;104(4):1014-22.
1999: Carrier R L; Papadaki M; Rupnick M; Schoen F J; Bursac N; Langer R; Freed L E; Vunjak-Novakovic G
Cardiac tissue engineering: cell seeding, cultivation parameters, and tissue construct characterization.
Biotechnology and bioengineering 1999;64(5):580-9.
1999: Ameer G A; Raghavan S; Sasisekharan R; Harmon W; Cooney C L; Langer R
Regional heparinization via simultaneous separation and reaction in a novel Taylor-Couette flow device.
Biotechnology and bioengineering 1999;63(5):618-24.
1999: Sinisterra R D; Shastri V P; Najjar R; Langer R
Encapsulation and release of rhodium(II) citrate and its association complex with hydroxypropyl-beta-cyclodextrin from biodegradable polymer microspheres.
Journal of pharmaceutical sciences 1999;88(5):574-6.
1999: Ben-Jebria A; Chen D; Eskew M L; Vanbever R; Langer R; Edwards D A
Large porous particles for sustained protection from carbachol-induced bronchoconstriction in guinea pigs.
Pharmaceutical research 1999;16(4):555-61.
1999: Langer R S; Vacanti J P
Tissue engineering: the challenges ahead.
Scientific American 1999;280(4):86-9.
1999: Ameer G A; Harmon W; Sasisekharan R; Langer R
Investigation of a whole blood fluidized bed Taylor-Couette flow device for enzymatic heparin neutralization.
Biotechnology and bioengineering 1999;62(5):602-8.
1999: Elisseeff J; Anseth K; Sims D; McIntosh W; Randolph M; Langer R
Transdermal photopolymerization for minimally invasive implantation.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3104-7.
1999: Ameer G A; Barabino G; Sasisekharan R; Harmon W; Cooney C L; Langer R
Ex vivo evaluation of a Taylor-Couette flow, immobilized heparinase I device for clinical application.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):2350-5.
1999: Ma P X; Langer R
Morphology and mechanical function of long-term in vitro engineered cartilage.
Journal of biomedical materials research 1999;44(2):217-21.
1999: Chen T; Langer R; Weaver J C
Charged microbeads are not transported across the human stratum corneum in vitro by short high-voltage pulses.
Bioelectrochemistry and bioenergetics (Lausanne, Switzerland) 1999;48(1):181-92.
1999: Anseth K S; Shastri V R; Langer R
Photopolymerizable degradable polyanhydrides with osteocompatibility.
Nature biotechnology 1999;17(2):156-9.
1999: Vunjak-Novakovic G; Martin I; Obradovic B; Treppo S; Grodzinsky A J; Langer R; Freed L E
Bioreactor cultivation conditions modulate the composition and mechanical properties of tissue-engineered cartilage.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1999;17(1):130-8.
1999: Santini J T; Cima M J; Langer R
A controlled-release microchip.
Nature 1999;397(6717):335-8.
1999: Caponetti G; Hrkach J S; Kriwet B; Poh M; Lotan N; Colombo P; Langer R
Microparticles of novel branched copolymers of lactic acid and amino acids: preparation and characterization.
Journal of pharmaceutical sciences 1999;88(1):136-41.
1999: Ando S; Putnam D; Pack D W; Langer R
PLGA microspheres containing plasmid DNA: preservation of supercoiled DNA via cryopreparation and carbohydrate stabilization.
Journal of pharmaceutical sciences 1999;88(1):126-30.
1998: Riesle J; Hollander A P; Langer R; Freed L E; Vunjak-Novakovic G
Collagen in tissue-engineered cartilage: types, structure, and crosslinks.
Journal of cellular biochemistry 1998;71(3):313-27.
1998: Gao J; Niklason L; Langer R
Surface hydrolysis of poly(glycolic acid) meshes increases the seeding density of vascular smooth muscle cells.
Journal of biomedical materials research 1998;42(3):417-24.
1998: Chen T; Segall E M; Langer R; Weaver J C
Skin electroporation: rapid measurements of the transdermal voltage and flux of four fluorescent molecules show a transition to large fluxes near 50 V.
Journal of pharmaceutical sciences 1998;87(11):1368-74.
1998: Patel N; Padera R; Sanders G H; Cannizzaro S M; Davies M C; Langer R; Roberts C J; Tendler S J; Williams P M; Shakesheff K M
Spatially controlled cell engineering on biodegradable polymer surfaces.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(14):1447-54.
1998: Chen T; Langer R; Weaver J C
Skin electroporation causes molecular transport across the stratum corneum through localized transport regions.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 1998;3(2):159-65.
1998: Edwards D A; Ben-Jebria A; Langer R
Recent advances in pulmonary drug delivery using large, porous inhaled particles.
Journal of applied physiology (Bethesda, Md. : 1985) 1998;85(2):379-85.
1998: Cannizzaro S M; Padera R F; Langer R; Rogers R A; Black F E; Davies M C; Tendler S J; Shakesheff K M
A novel biotinylated degradable polymer for cell-interactive applications.
Biotechnology and bioengineering 1998;58(5):529-35.
1998: Schwendeman S P; Tobío M; Joworowicz M; Alonso M J; Langer R
New strategies for the microencapsulation of tetanus vaccine.
Journal of microencapsulation 1998;15(3):299-318.
1998: Langer R
Drug delivery and targeting.
Nature 1998;392(6679 Suppl):5-10.
1998: Freed L E; Hollander A P; Martin I; Barry J R; Langer R; Vunjak-Novakovic G
Chondrogenesis in a cell-polymer-bioreactor system.
Experimental cell research 1998;240(1):58-65.
1998: Vunjak-Novakovic G; Obradovic B; Martin I; Bursac P M; Langer R; Freed L E
Dynamic cell seeding of polymer scaffolds for cartilage tissue engineering.
Biotechnology progress 1998;14(2):193-202.
1998: Costantino H R; Schwendeman S P; Langer R; Klibanov A M
Deterioration of lyophilized pharmaceutical proteins.
Biochemistry. Biokhimii?a 1998;63(3):357-63.
1998: Evora C; Soriano I; Rogers R A; Shakesheff K N; Hanes J; Langer R
Relating the phagocytosis of microparticles by alveolar macrophages to surface chemistry: the effect of 1,2-dipalmitoylphosphatidylcholine.
Journal of controlled release : official journal of the Controlled Release Society 1998;51(2-3):143-52.
1998: Tobío M; Gref R; Sánchez A; Langer R; Alonso M J
Stealth PLA-PEG nanoparticles as protein carriers for nasal administration.
Pharmaceutical research 1998;15(2):270-5.
1998: Gao J; Niklason L; Zhao X M; Langer R
Surface modification of polyanhydride microspheres.
Journal of pharmaceutical sciences 1998;87(2):246-8.
1998: Hanes J; Chiba M; Langer R
Degradation of porous poly(anhydride-co-imide) microspheres and implications for controlled macromolecule delivery.
Biomaterials 1998;19(1-3):163-72.
1997: Batycky R P; Hanes J; Langer R; Edwards D A
A theoretical model of erosion and macromolecular drug release from biodegrading microspheres.
Journal of pharmaceutical sciences 1997;86(12):1464-77.
1997: Freed L E; Langer R; Martin I; Pellis N R; Vunjak-Novakovic G
Tissue engineering of cartilage in space.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):13885-90.
1997: Mooney D J; Sano K; Kaufmann P M; Majahod K; Schloo B; Vacanti J P; Langer R
Long-term engraftment of hepatocytes transplanted on biodegradable polymer sponges.
Journal of biomedical materials research 1997;37(3):413-20.
1997: Cook A D; Pajvani U B; Hrkach J S; Cannizzaro S M; Langer R
Colorimetric analysis of surface reactive amino groups on poly(lactic acid-co-lysine):poly(lactic acid) blends.
Biomaterials 1997;18(21):1417-24.
1997: Mitragotri S; Blankschtein D; Langer R
An explanation for the variation of the sonophoretic transdermal transport enhancement from drug to drug.
Journal of pharmaceutical sciences 1997;86(10):1190-2.
1997: Johnson M E; Blankschtein D; Langer R
Evaluation of solute permeation through the stratum corneum: lateral bilayer diffusion as the primary transport mechanism.
Journal of pharmaceutical sciences 1997;86(10):1162-72.
1997: Schmidt C E; Shastri V R; Vacanti J P; Langer R
Stimulation of neurite outgrowth using an electrically conducting polymer.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(17):8948-53.
1997: Langer R
Tissue engineering: a new field and its challenges.
Pharmaceutical research 1997;14(7):840-1.
1997: Chiba M; Hanes J; Langer R
Controlled protein delivery from biodegradable tyrosine-containing poly(anhydride-co-imide) microspheres.
Biomaterials 1997;18(13):893-901.
1997: Cook A D; Hrkach J S; Gao N N; Johnson I M; Pajvani U B; Cannizzaro S M; Langer R
Characterization and development of RGD-peptide-modified poly(lactic acid-co-lysine) as an interactive, resorbable biomaterial.
Journal of biomedical materials research 1997;35(4):513-23.
1997: Edwards D A; Hanes J; Caponetti G; Hrkach J; Ben-Jebria A; Eskew M L; Mintzes J; Deaver D; Lotan N; Langer R
Large porous particles for pulmonary drug delivery.
Science (New York, N.Y.) 1997;276(5320):1868-71.
1997: Chen H; Langer R
Magnetically-responsive polymerized liposomes as potential oral delivery vehicles.
Pharmaceutical research 1997;14(4):537-40.
1997: Kim T H; Lee H M; Utsonomiya H; Ma P; Langer R; Schmidt E V; Vacanti J P
Enhanced survival of transgenic hepatocytes expressing hepatocyte growth factor in hepatocyte tissue engineering.
Transplantation proceedings 1997;29(1-2):858-60.
1997: Hrkach J S; Peracchia M T; Domb A; Lotan N; Langer R
Nanotechnology for biomaterials engineering: structural characterization of amphiphilic polymeric nanoparticles by 1H NMR spectroscopy.
Biomaterials 1997;18(1):27-30.
1997: Gref R; Minamitake Y; Peracchia M T; Domb A; Trubetskoy V; Torchilin V; Langer R
Poly(ethylene glycol)-coated nanospheres: potential carriers for intravenous drug administration.
Pharmaceutical biotechnology 1997;10():167-98.
1996: Prausnitz M R; Gimm J A; Guy R H; Langer R; Weaver J C; Cullander C
Imaging regions of transport across human stratum corneum during high-voltage and low-voltage exposures.
Journal of pharmaceutical sciences 1996;85(12):1363-70.
1996: Brown L R; Edelman E R; Fischel-Ghodsian F; Langer R
Characterization of glucose-mediated insulin release from implantable polymers.
Journal of pharmaceutical sciences 1996;85(12):1341-5.
1996: Costantino H R; Schwendeman S P; Griebenow K; Klibanov A M; Langer R
The secondary structure and aggregation of lyophilized tetanus toxoid.
Journal of pharmaceutical sciences 1996;85(12):1290-3.
1996: Yaszemski M J; Payne R G; Hayes W C; Langer R; Mikos A G
In vitro degradation of a poly(propylene fumarate)-based composite material.
Biomaterials 1996;17(22):2127-30.
1996: Castillo J; Curley J; Hotz J; Uezono M; Tigner J; Chasin M; Wilder R; Langer R; Berde C
Glucocorticoids prolong rat sciatic nerve blockade in vivo from bupivacaine microspheres.
Anesthesiology 1996;85(5):1157-66.
1996: Johnson M E; Berk D A; Blankschtein D; Golan D E; Jain R K; Langer R S
Lateral diffusion of small compounds in human stratum corneum and model lipid bilayer systems.
Biophysical journal 1996;71(5):2656-68.
1996: Shinoka T; Ma P X; Shum-Tim D; Breuer C K; Cusick R A; Zund G; Langer R; Vacanti J P; Mayer J E
Tissue-engineered heart valves. Autologous valve leaflet replacement study in a lamb model.
Circulation 1996;94(9 Suppl):II164-8.
1996: Chen H; Torchilin V; Langer R
Lectin-bearing polymerized liposomes as potential oral vaccine carriers.
Pharmaceutical research 1996;13(9):1378-83.
1996: Edwards D A; Schneck F; Zhang I; Davis A M; Chen H; Langer R
Spontaneous vesicle formation at lipid bilayer membranes.
Biophysical journal 1996;71(3):1208-14.
1996: Godavarti R; Davis M; Venkataraman G; Cooney C; Langer R; Sasisekharan R
Heparinase III from Flavobacterium heparinum: cloning and recombinant expression in Escherichia coli.
Biochemical and biophysical research communications 1996;225(3):751-8.
1996: Mooney D J; Baldwin D F; Suh N P; Vacanti J P; Langer R
Novel approach to fabricate porous sponges of poly(D,L-lactic-co-glycolic acid) without the use of organic solvents.
Biomaterials 1996;17(14):1417-22.
1996: Johnson M E; Mitragotri S; Patel A; Blankschtein D; Langer R
Synergistic effects of chemical enhancers and therapeutic ultrasound on transdermal drug delivery.
Journal of pharmaceutical sciences 1996;85(7):670-9.
1996: Sanchez A; Gupta R K; Alonso M J; Siber G R; Langer R
Pulsed controlled-released system for potential use in vaccine delivery.
Journal of pharmaceutical sciences 1996;85(6):547-52.
1996: Curley J; Castillo J; Hotz J; Uezono M; Hernandez S; Lim J O; Tigner J; Chasin M; Langer R; Berde C
Prolonged regional nerve blockade. Injectable biodegradable bupivacaine/polyester microspheres.
Anesthesiology 1996;84(6):1401-10.
1996: Sano K; Cusick R A; Lee H; Pollok J M; Kaufmann P M; Uyama S; Mooney D; Langer R; Vacanti J P
Regenerative signals for heterotopic hepatocyte transplantation.
Transplantation proceedings 1996;28(3):1857-8.
1996: Attawia M A; Uhrich K E; Botchwey E; Langer R; Laurencin C T
In vitro bone biocompatibility of poly (anhydride-co-imides) containing pyromellitylimidoalanine.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1996;14(3):445-54.
1996: Godavarti R; Cooney C L; Langer R; Sasisekharan R
Heparinase I from Flavobacterium heparinum. Identification of a critical histidine residue essential for catalysis as probed by chemical modification and site-directed mutagenesis.
Biochemistry 1996;35(21):6846-52.
1996: Ernst S; Venkataraman G; Winkler S; Godavarti R; Langer R; Cooney C L; Sasisekharan R
Expression in Escherichia coli, purification and characterization of heparinase I from Flavobacterium heparinum.
The Biochemical journal 1996;315 ( Pt 2)():589-97.
1996: Edwards D A; Gooch K J; Zhang I; McKinley G H; Langer R
The nucleation of receptor-mediated endocytosis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(5):1786-91.
1996: Mitragotri S; Blankschtein D; Langer R
Transdermal drug delivery using low-frequency sonophoresis.
Pharmaceutical research 1996;13(3):411-20.
1996: Sasisekharan R; Venkataraman G; Godavarti R; Ernst S; Cooney C L; Langer R
Heparinase I from Flavobacterium heparinum. Mapping and characterization of the heparin binding domain.
The Journal of biological chemistry 1996;271(6):3124-31.
1996: Pliquett U F; Zewert T E; Chen T; Langer R; Weaver J C
Imaging of fluorescent molecule and small ion transport through human stratum corneum during high voltage pulsing: localized transport regions are involved.
Biophysical chemistry 1996;58(1-2):185-204.
1996: Yaszemski M J; Payne R G; Hayes W C; Langer R; Mikos A G
Evolution of bone transplantation: molecular, cellular and tissue strategies to engineer human bone.
Biomaterials 1996;17(2):175-85.
1996: Mooney D J; Mazzoni C L; Breuer C; McNamara K; Hern D; Vacanti J P; Langer R
Stabilized polyglycolic acid fibre-based tubes for tissue engineering.
Biomaterials 1996;17(2):115-24.
1996: Venkataraman G; Sasisekharan V; Herr A B; Ornitz D M; Waksman G; Cooney C L; Langer R; Sasisekharan R
Preferential self-association of basic fibroblast growth factor is stabilized by heparin during receptor dimerization and activation.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(2):845-50.
1996: Schwendeman S P; Costantino H R; Gupta R K; Tobio M; Chang A C; Alonso M J; Siber G R; Langer R
Strategies for stabilising tetanus toxoid towards the development of a single-dose tetanus vaccine.
Developments in biological standardization 1996;87():293-306.
1995: Shinoka T; Breuer C K; Tanel R E; Zund G; Miura T; Ma P X; Langer R; Vacanti J P; Mayer J E
Tissue engineering heart valves: valve leaflet replacement study in a lamb model.
The Annals of thoracic surgery 1995;60(6 Suppl):S513-6.
1995: Ma P X; Schloo B; Mooney D; Langer R
Development of biomechanical properties and morphogenesis of in vitro tissue engineered cartilage.
Journal of biomedical materials research 1995;29(12):1587-95.
1995: Prausnitz M R; Edelman E R; Gimm J A; Langer R; Weaver J C
Transdermal delivery of heparin by skin electroporation.
Bio/technology (Nature Publishing Company) 1995;13(11):1205-9.
1995: Sasisekharan R; Leckband D; Godavarti R; Venkataraman G; Cooney C L; Langer R
Heparinase I from Flavobacterium heparinum: the role of the cysteine residue in catalysis as probed by chemical modification and site-directed mutagenesis.
Biochemistry 1995;34(44):14441-8.
1995: Costantino H R; Griebenow K; Mishra P; Langer R; Klibanov A M
Fourier-transform infrared spectroscopic investigation of protein stability in the lyophilized form.
Biochimica et biophysica acta 1995;1253(1):69-74.
1995: Pliquett U; Langer R; Weaver J C
Changes in the passive electrical properties of human stratum corneum due to electroporation.
Biochimica et biophysica acta 1995;1239(2):111-21.
1995: Schwendeman S P; Costantino H R; Gupta R K; Siber G R; Klibanov A M; Langer R
Stabilization of tetanus and diphtheria toxoids against moisture-induced aggregation.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(24):11234-8.
1995: Attawia M A; Uhrich K E; Botchwey E; Fan M; Langer R; Laurencin C T
Cytotoxicity testing of poly(anhydride-co-imides) for orthopedic applications.
Journal of biomedical materials research 1995;29(10):1233-40.
1995: Johnson M E; Blankschtein D; Langer R
Permeation of steroids through human skin.
Journal of pharmaceutical sciences 1995;84(9):1144-6.
1995: Mitragotri S; Blankschtein D; Langer R
Ultrasound-mediated transdermal protein delivery.
Science (New York, N.Y.) 1995;269(5225):850-3.
1995: Mooney D J; Park S; Kaufmann P M; Sano K; McNamara K; Vacanti J P; Langer R
Biodegradable sponges for hepatocyte transplantation.
Journal of biomedical materials research 1995;29(8):959-65.
1995: Zewert T E; Pliquett U F; Langer R; Weaver J C
Transdermal transport of DNA antisense oligonucleotides by electroporation.
Biochemical and biophysical research communications 1995;212(2):286-92.
1995: Venkataraman G; Sasisekharan V; Cooney C L; Langer R; Sasisekharan R
Complex flexibility of the transforming growth factor beta superfamily.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(12):5406-10.
1995: Mooney D J; Langer R; Ingber D E
Cytoskeletal filament assembly and the control of cell spreading and function by extracellular matrix.
Journal of cell science 1995;108 ( Pt 6)():2311-20.
1995: Mitragotri S; Edwards D A; Blankschtein D; Langer R
A mechanistic study of ultrasonically-enhanced transdermal drug delivery.
Journal of pharmaceutical sciences 1995;84(6):697-706.
1995: Costantino H R; Langer R; Klibanov A M
Aggregation of a lyophilized pharmaceutical protein, recombinant human albumin: effect of moisture and stabilization by excipients.
Bio/technology (Nature Publishing Company) 1995;13(5):493-6.
1995: Prausnitz M R; Corbett J D; Gimm J A; Golan D E; Langer R; Weaver J C
Millisecond measurement of transport during and after an electroporation pulse.
Biophysical journal 1995;68(5):1864-70.
1995: Wake M C; Mikos A G; Sarakinos G; Vacanti J P; Langer R
Dynamics of fibrovascular tissue ingrowth in hydrogel foams.
Cell transplantation 1995;4(3):275-9.
1995: Okada J; Cohen S; Langer R
In vitro evaluation of polymerized liposomes as an oral drug delivery system.
Pharmaceutical research 1995;12(4):576-82.
1995: Shefer S D; Breslau J; Langer R
Computer simulation of low-density lipoprotein removal in the presence of a bioreactor containing phospholipase A2.
Biotechnology progress 1995;11(2):133-9.
1995: Langer R
1994 Whitaker Lecture: polymers for drug delivery and tissue engineering.
Annals of biomedical engineering 1995;23(2):101-11.
1995: Takeda T; Kim T H; Lee S K; Langer R; Vacanti J P
Hepatocyte transplantation in biodegradable polymer scaffolds using the Dalmatian dog model of hyperuricosuria.
Transplantation proceedings 1995;27(1):635-6.
1995: Langer R; Vacanti J P; Vacanti C A; Atala A; Freed L E; Vunjak-Novakovic G
Tissue engineering: biomedical applications.
Tissue engineering 1995;1(2):151-61.
1995: Mooney D J; Breuer C; McNamara K; Vacanti J P; Langer R
Fabricating tubular devices from polymers of lactic and glycolic Acid for tissue engineering.
Tissue engineering 1995;1(2):107-18.
1995: Yaszemski M J; Payne R G; Hayes W C; Langer R S; Aufdemorte T B; Mikos A G
The ingrowth of new bone tissue and initial mechanical properties of a degrading polymeric composite scaffold.
Tissue engineering 1995;1(1):41-52.
1995: Ernst S; Langer R; Cooney C L; Sasisekharan R
Enzymatic degradation of glycosaminoglycans.
Critical reviews in biochemistry and molecular biology 1995;30(5):387-444.
1995: Hanes J; Chiba M; Langer R
Polymer microspheres for vaccine delivery.
Pharmaceutical biotechnology 1995;6():389-412.
1994: Mooney D J; Kaufmann P M; Sano K; McNamara K M; Vacanti J P; Langer R
Transplantation of hepatocytes using porous, biodegradable sponges.
Transplantation proceedings 1994;26(6):3425-6.
1994: Cao Y; Vacanti J P; Ma X; Paige K T; Upton J; Chowanski Z; Schloo B; Langer R; Vacanti C A
Generation of neo-tendon using synthetic polymers seeded with tenocytes.
Transplantation proceedings 1994;26(6):3390-2.
1994: Sakata J; Vacanti C A; Schloo B; Healy G B; Langer R; Vacanti J P
Tracheal composites tissue engineered from chondrocytes, tracheal epithelial cells, and synthetic degradable scaffolding.
Transplantation proceedings 1994;26(6):3309-10.
1994: Prausnitz M R; Pliquett U; Langer R; Weaver J C
Rapid temporal control of transdermal drug delivery by electroporation.
Pharmaceutical research 1994;11(12):1834-7.
1994: Costantino H R; Langer R; Klibanov A M
Solid-phase aggregation of proteins under pharmaceutically relevant conditions.
Journal of pharmaceutical sciences 1994;83(12):1662-9.
1994: Shieh L; Tamada J; Chen I; Pang J; Domb A; Langer R
Erosion of a new family of biodegradable polyanhydrides.
Journal of biomedical materials research 1994;28(12):1465-75.
1994: Mooney D J; Hansen L K; Langer R; Vacanti J P; Ingber D E
Extracellular matrix controls tubulin monomer levels in hepatocytes by regulating protein turnover.
Molecular biology of the cell 1994;5(12):1281-8.
1994: Ferreira J P; Sasisekharan R; Louie O; Langer R
A study on the functional subunits of phospholipases A2 by enzyme immobilization.
The Biochemical journal 1994;303 ( Pt 2)():527-30.
1994: Edwards D A; Langer R
A linear theory of transdermal transport phenomena.
Journal of pharmaceutical sciences 1994;83(9):1315-34.
1994: Rosenthal R A; Moses M A; Shintani Y; Megyesi J F; Langer R; Folkman J
Purification and characterization of two collagenase inhibitors from mouse sarcoma 180 conditioned medium.
Journal of cellular biochemistry 1994;56(1):97-105.
1994: Puelacher W C; Mooney D; Langer R; Upton J; Vacanti J P; Vacanti C A
Design of nasoseptal cartilage replacements synthesized from biodegradable polymers and chondrocytes.
Biomaterials 1994;15(10):774-8.
1994: Freed L E; Grande D A; Lingbin Z; Emmanual J; Marquis J C; Langer R
Joint resurfacing using allograft chondrocytes and synthetic biodegradable polymer scaffolds.
Journal of biomedical materials research 1994;28(8):891-9.
1994: Ferreira J P; Sasisekharan R; Louie O; Langer R
Carbodiimide modification enhances activity of pig pancreatic phospholipase A2.
European journal of biochemistry / FEBS 1994;223(2):611-6.
1994: Johnson L B; Aiken J; Mooney D; Schloo B L; Griffith-Cima L; Langer R; Vacanti J P
The mesentery as a laminated vascular bed for hepatocyte transplantation.
Cell transplantation 1994;3(4):273-81.
1994: Freed L E; Vunjak-Novakovic G; Biron R J; Eagles D B; Lesnoy D C; Barlow S K; Langer R
Biodegradable polymer scaffolds for tissue engineering.
Bio/technology (Nature Publishing Company) 1994;12(7):689-93.
1994: Venkataraman G; Sasisekharan V; Cooney C L; Langer R; Sasisekharan R
A stereochemical approach to pyranose ring flexibility: its implications for the conformation of dermatan sulfate.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(13):6171-5.
1994: Prausnitz M R; Milano C D; Gimm J A; Langer R; Weaver J C
Quantitative study of molecular transport due to electroporation: uptake of bovine serum albumin by erythrocyte ghosts.
Biophysical journal 1994;66(5):1522-30.
1994: Wong J Y; Langer R; Ingber D E
Electrically conducting polymers can noninvasively control the shape and growth of mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(8):3201-4.
1994: Alonso M J; Gupta R K; Min C; Siber G R; Langer R
Biodegradable microspheres as controlled-release tetanus toxoid delivery systems.
Vaccine 1994;12(4):299-306.
1994: Gref R; Minamitake Y; Peracchia M T; Trubetskoy V; Torchilin V; Langer R
Biodegradable long-circulating polymeric nanospheres.
Science (New York, N.Y.) 1994;263(5153):1600-3.
1994: Wu M P; Tamada J A; Brem H; Langer R
In vivo versus in vitro degradation of controlled release polymers for intracranial surgical therapy.
Journal of biomedical materials research 1994;28(3):387-95.
1994: Mooney D J; Organ G; Vacanti J P; Langer R
Design and fabrication of biodegradable polymer devices to engineer tubular tissues.
Cell transplantation 1994;3(2):203-10.
1994: Sasisekharan R; Moses M A; Nugent M A; Cooney C L; Langer R
Heparinase inhibits neovascularization.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(4):1524-8.
1994: Mikos A G; Lyman M D; Freed L E; Langer R
Wetting of poly(L-lactic acid) and poly(DL-lactic-co-glycolic acid) foams for tissue culture.
Biomaterials 1994;15(1):55-8.
1994: Costantino H R; Langer R; Klibanov A M
Moisture-induced aggregation of lyophilized insulin.
Pharmaceutical research 1994;11(1):21-9.
1994: Tabata Y; Domb A; Langer R
Injectable polyanhydride granules provide controlled release of water-soluble drugs with a reduced initial burst.
Journal of pharmaceutical sciences 1994;83(1):5-11.
1993: Prausnitz M R; Bose V G; Langer R; Weaver J C
Electroporation of mammalian skin: a mechanism to enhance transdermal drug delivery.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(22):10504-8.
1993: Masters D B; Berde C B; Dutta S; Turek T; Langer R
Sustained local anesthetic release from bioerodible polymer matrices: a potential method for prolonged regional anesthesia.
Pharmaceutical research 1993;10(10):1527-32.
1993: Ferreira J P; Sasisekharan R; Louie O; Langer R
Influence of chemistry in immobilization of cobra venom phospholipase A2: implications as to mechanism.
Biochemistry 1993;32(32):8098-102.
1993: Masters D B; Berde C B; Dutta S K; Griggs C T; Hu D; Kupsky W; Langer R
Prolonged regional nerve blockade by controlled release of local anesthetic from a biodegradable polymer matrix.
Anesthesiology 1993;79(2):340-6.
1993: Edelman E R; Langer R
Optimization of release from magnetically controlled polymeric drug release devices.
Biomaterials 1993;14(8):621-6.
1993: Alonso M J; Cohen S; Park T G; Gupta R K; Siber G R; Langer R
Determinants of release rate of tetanus vaccine from polyester microspheres.
Pharmaceutical research 1993;10(7):945-53.
1993: Prausnitz M R; Lau B S; Milano C D; Conner S; Langer R; Weaver J C
A quantitative study of electroporation showing a plateau in net molecular transport.
Biophysical journal 1993;65(1):414-22.
1993: Langer R; Vacanti J P
Tissue engineering.
Science (New York, N.Y.) 1993;260(5110):920-6.
1993: Ron E; Turek T; Mathiowitz E; Chasin M; Hageman M; Langer R
Controlled release of polypeptides from polyanhydrides.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(9):4176-80.
1993: Mikos A G; Sarakinos G; Leite S M; Vacanti J P; Langer R
Laminated three-dimensional biodegradable foams for use in tissue engineering.
Biomaterials 1993;14(5):323-30.
1993: Tabata Y; Gutta S; Langer R
Controlled delivery systems for proteins using polyanhydride microspheres.
Pharmaceutical research 1993;10(4):487-96.
1993: Sasisekharan R; Bulmer M; Moremen K W; Cooney C L; Langer R
Cloning and expression of heparinase I gene from Flavobacterium heparinum.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3660-4.
1993: Labeque R; Mullon C J; Ferreira J P; Lees R S; Langer R
Enzymatic modification of plasma low density lipoproteins in rabbits: a potential treatment for hypercholesterolemia.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3476-80.
1993: Shefer S D; Ferreira J; Mullon C J; Langer R
Extracorporeal enzymatic removal of low density lipoproteins in rabbits: efficacy and safety.
The International journal of artificial organs 1993;16(4):218-28.
1993: Freed L E; Vunjak-Novakovic G; Langer R
Cultivation of cell-polymer cartilage implants in bioreactors.
Journal of cellular biochemistry 1993;51(3):257-64.
1993: Laurencin C T; Gerhart T; Witschger P; Satcher R; Domb A; Rosenberg A E; Hanff P; Edsberg L; Hayes W; Langer R
Bioerodible polyanhydrides for antibiotic drug delivery: in vivo osteomyelitis treatment in a rat model system.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1993;11(2):256-62.
1993: Tabata Y; Langer R
Polyanhydride microspheres that display near-constant release of water-soluble model drug compounds.
Pharmaceutical research 1993;10(3):391-9.
1993: Fontaine M; Hansen L K; Thompson S; Uyama S; Ingber D E; Langer R; Vacanti J P
Transplantation of genetically altered hepatocytes using cell-polymer constructs.
Transplantation proceedings 1993;25(1 Pt 2):1002-4.
1993: Mikos A G; Bao Y; Cima L G; Ingber D E; Vacanti J P; Langer R
Preparation of poly(glycolic acid) bonded fiber structures for cell attachment and transplantation.
Journal of biomedical materials research 1993;27(2):183-9.
1993: Tamada J A; Langer R
Erosion kinetics of hydrolytically degradable polymers.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(2):552-6.
1993: Freed L E; Marquis J C; Nohria A; Emmanual J; Mikos A G; Langer R
Neocartilage formation in vitro and in vivo using cells cultured on synthetic biodegradable polymers.
Journal of biomedical materials research 1993;27(1):11-23.
1993: Wald H L; Sarakinos G; Lyman M D; Mikos A G; Vacanti J P; Langer R
Cell seeding in porous transplantation devices.
Biomaterials 1993;14(4):270-8.
1993: Freed L E; Vunjak-Novakovic G V; Bernstein H; Cooney C L; Langer R
Kinetics of immobilized heparinase in human blood.
Annals of biomedical engineering 1993;21(1):67-76.
1993: Freed L E; Vunjak-Novakovic G V; Drinker P A; Langer R
Bioreactor based on suspended particles of immobilized enzyme.
Annals of biomedical engineering 1993;21(1):57-65.
1992: D'Emanuele A; Hill J; Tamada J A; Domb A J; Langer R
Molecular weight changes in polymer erosion.
Pharmaceutical research 1992;9(10):1279-83.
1992: Simons M; Edelman E R; DeKeyser J L; Langer R; Rosenberg R D
Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo.
Nature 1992;359(6390):67-70.
1992: Soltys P J; Mullon C; Langer R
Oral treatment for jaundice using immobilized bilirubin oxidase.
Artificial organs 1992;16(4):331-5.
1992: Mooney D; Hansen L; Vacanti J; Langer R; Farmer S; Ingber D
Switching from differentiation to growth in hepatocytes: control by extracellular matrix.
Journal of cellular physiology 1992;151(3):497-505.
1992: During M J; Freese A; Deutch A Y; Kibat P G; Sabel B A; Langer R; Roth R H
Biochemical and behavioral recovery in a rodent model of Parkinson's disease following stereotactic implantation of dopamine-containing liposomes.
Experimental neurology 1992;115(2):193-9.
1992: Park T G; Cohen S; Langer R
Controlled protein release from polyethyleneimine-coated poly(L-lactic acid)/pluronic blend matrices.
Pharmaceutical research 1992;9(1):37-9.
1992: Wintermantel E; Cima L; Schloo B; Langer R
Angiopolarity of cell carriers: directional angiogenesis in resorbable liver cell transplantation devices.
EXS 1992;61():331-4.
1992: Tamada J; Langer R
The development of polyanhydrides for drug delivery applications.
Journal of biomaterials science. Polymer edition 1992;3(4):315-53.
1991: Cohen S; Bernstein H; Hewes C; Chow M; Langer R
The pharmacokinetics of, and humoral responses to, antigen delivered by microencapsulated liposomes.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(23):10440-4.
1991: Sluzky V; Tamada J A; Klibanov A M; Langer R
Kinetics of insulin aggregation in aqueous solutions upon agitation in the presence of hydrophobic surfaces.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(21):9377-81.
1991: Edelman E R; Mathiowitz E; Langer R; Klagsbrun M
Controlled and modulated release of basic fibroblast growth factor.
Biomaterials 1991;12(7):619-26.
1991: Wintermantel E; Cima L; Schloo B; Langer R
Angiopolarity: a new design parameter for cell transplantation devices and its application to degradable systems.
ASAIO transactions / American Society for Artificial Internal Organs 1991;37(3):M334-6.
1991: Cima L G; Vacanti J P; Vacanti C; Ingber D; Mooney D; Langer R
Tissue engineering by cell transplantation using degradable polymer substrates.
Journal of biomechanical engineering 1991;113(2):143-51.
1991: Carmen Bañó M; Cohen S; Visscher K B; Allcock H R; Langer R
A novel synthetic method for hybridoma cell encapsulation.
Bio/technology (Nature Publishing Company) 1991;9(5):468-71.
1991: Langer R; Moses M
Biocompatible controlled release polymers for delivery of polypeptides and growth factors.
Journal of cellular biochemistry 1991;45(4):340-5.
1991: Langer R; Kost J
Real time response polymeric delivery systems.
Annals of the New York Academy of Sciences 1991;618():330-4.
1990: Laurencin C; Domb A; Morris C; Brown V; Chasin M; McConnell R; Lange N; Langer R
Poly(anhydride) administration in high doses in vivo: studies of biocompatibility and toxicology.
Journal of biomedical materials research 1990;24(11):1463-81.
1990: Langer R; Cima L G; Tamada J A; Wintermantel E
Future directions in biomaterials.
Biomaterials 1990;11(9):738-45.
1990: Laurencin C T; Pierre-Jacques H M; Langer R
Toxicology and biocompatibility considerations in the evaluation of polymeric materials for biomedical applications.
Clinics in laboratory medicine 1990;10(3):549-70.
1990: Langer R
New methods of drug delivery.
Science (New York, N.Y.) 1990;249(4976):1527-33.
1990: Lucas P A; Laurencin C; Syftestad G T; Domb A; Goldberg V M; Caplan A I; Langer R
Ectopic induction of cartilage and bone by water-soluble proteins from bovine bone using a polyanhydride delivery vehicle.
Journal of biomedical materials research 1990;24(7):901-11.
1990: Mathiowitz E; Kline D; Langer R
Morphology of polyanhydride microsphere delivery systems.
Scanning microscopy 1990;4(2):329-40.
1990: Kibat P G; Igari Y; Wheatley M A; Eisen H N; Langer R
Enzymatically activated microencapsulated liposomes can provide pulsatile drug release.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1990;4(8):2533-9.
1990: Aiken J; Cima L; Schloo B; Mooney D; Johnson L; Langer R; Vacanti J P
Studies in rat liver perfusion for optimal harvest of hepatocytes.
Journal of pediatric surgery 1990;25(1):140-4; discussion 144-5.
1989: During M J; Freese A; Sabel B A; Saltzman W M; Deutch A; Roth R H; Langer R
Controlled release of dopamine from a polymeric brain implant: in vivo characterization.
Annals of neurology 1989;25(4):351-6.
1989: Freese A; Sabel B A; Saltzman W M; During M J; Langer R
Controlled release of dopamine from a polymeric brain implant: in vitro characterization.
Experimental neurology 1989;103(3):234-8.
1989: Larsen A K; Rice K G; Linhardt R J; Wogan G; Langer R
Resistance of heparinase-derived heparin fragments to biotransformation.
The Journal of biological chemistry 1989;264(3):1570-7.
1988: Bernstein H; Langer R
Ex vivo model of an immobilized-enzyme reactor.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(22):8751-5.
1988: Langer R
Biodegradable polymers for drug delivery to the brain.
ASAIO transactions / American Society for Artificial Internal Organs 1988;34(4):945-6.
1988: Bindschaedler C; Leong K; Mathiowitz E; Langer R
Polyanhydride microsphere formulation by solvent extraction.
Journal of pharmaceutical sciences 1988;77(8):696-8.
1988: Freed L E; Vunjak G V; Drinker P A; Langer R
A novel bioreactor based on suspended particles of agarose-immobilized species.
ASAIO transactions / American Society for Artificial Internal Organs 1988;34(3):732-8.
1988: Fischel-Ghodsian F; Brown L; Mathiowitz E; Brandenburg D; Langer R
Enzymatically controlled drug delivery.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(7):2403-6.
1988: Vacanti J P; Morse M A; Saltzman W M; Domb A J; Perez-Atayde A; Langer R
Selective cell transplantation using bioabsorbable artificial polymers as matrices.
Journal of pediatric surgery 1988;23(1 Pt 2):3-9.
1988: Bernstein H; Yang V C; Cooney C L; Langer R
Immobilized heparin lyase system for blood deheparinization.
Methods in enzymology 1988;137():515-29.
1988: Brown L; Langer R
Transdermal delivery of drugs.
Annual review of medicine 1988;39():221-9.
1987: Kost J; Wolfrum J; Langer R
Magnetically enhanced insulin release in diabetic rats.
Journal of biomedical materials research 1987;21(12):1367-73.
1987: Laurencin C T; Koh H J; Neenan T X; Allcock H R; Langer R
Controlled release using a new bioerodible polyphosphazene matrix system.
Journal of biomedical materials research 1987;21(10):1231-46.
1987: Yang V C; Bernstein H; Cooney C L; Langer R
Large scale preparation and characterization of mucopolysaccharase contamination free heparinase.
Applied biochemistry and biotechnology 1987;16():35-50.
1987: Bernstein H; Yang V C; Langer R
An investigation of heparinase immobilization.
Applied biochemistry and biotechnology 1987;16():129-43.
1986: Yang V C; Bernstein H; Cooney C L; Kadam J C; Langer R
Removal of the anticoagulant activities of the low molecular weight heparin fractions and fragments with flavobacterial heparinase.
Thrombosis research 1986;44(5):599-610.
1985: Leong K W; Brott B C; Langer R
Bioerodible polyanhydrides as drug-carrier matrices. I: Characterization, degradation, and release characteristics.
Journal of biomedical materials research 1985;19(8):941-55.
1985: Kost J; Noecker R; Kunica E; Langer R
Magnetically controlled release systems: effect of polymer composition.
Journal of biomedical materials research 1985;19(8):935-40.
1985: Yang V C; Linhardt R J; Bernstein H; Cooney C L; Langer R
Purification and characterization of heparinase from Flavobacterium heparinum.
The Journal of biological chemistry 1985;260(3):1849-57.

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