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Ute Bank

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Peter Röhnert; Werner Schmidt; Michael Täger; Sabine Wrenger; Siegfried Ansorge; Ute Bank; Patrick Emmerlich; Alexander Goihl; Karsten Nordhoff; Dirk Reinhold; Frank Striggow
Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia.
Aliza Biton; Siegfried Ansorge; Ute Bank; Dirk Reinhold; Michael Täger; Stefan Brocke
Divergent actions by inhibitors of DP IV and APN family enzymes on CD4+ Teff cell motility and functions.
Ute Bank; Anke Heimburg; Astrid Wohlfarth; Gudrun Koch; Karsten Nordhoff; Heiko Julius; Martin Helmuth; Doreen Breyer; Dirk Reinhold; Michael Täger; Siegfried Ansorge
Outside or inside: role of the subcellular localization of DP4-like enzymes for substrate conversion and inhibitor effects.

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2012: Peter Röhnert; Werner Schmidt; Michael Täger; Sabine Wrenger; Siegfried Ansorge; Ute Bank; Patrick Emmerlich; Alexander Goihl; Karsten Nordhoff; Dirk Reinhold; Frank Striggow
Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia.
Journal of neuroinflammation 2012;9():44.
2011: Aliza Biton; Siegfried Ansorge; Ute Bank; Dirk Reinhold; Michael Täger; Stefan Brocke
Divergent actions by inhibitors of DP IV and APN family enzymes on CD4+ Teff cell motility and functions.
Immunobiology 2011;216(12):1295-301.
2011: Ute Bank; Anke Heimburg; Astrid Wohlfarth; Gudrun Koch; Karsten Nordhoff; Heiko Julius; Martin Helmuth; Doreen Breyer; Dirk Reinhold; Michael Täger; Siegfried Ansorge
Outside or inside: role of the subcellular localization of DP4-like enzymes for substrate conversion and inhibitor effects.
Biological chemistry 2011;392(3):169-87.
2011: Dirk Reinhold; Ute Bank; Dominik Entz; Alexander Goihl; Diana Stoye; Sabine Wrenger; Stefan Brocke; Anja Thielitz; Sofia Stefin; Karsten Nordhoff; Anke Heimburg; Michael Täger; Siegfried Ansorge
PETIR-001, a dual inhibitor of dipeptidyl peptidase IV (DP IV) and aminopeptidase N (APN), ameliorates experimental autoimmune encephalomyelitis in SJL/J mice.
Biological chemistry 2011;392(3):233-7.
2011: Siegfried Ansorge; Karsten Nordhoff; Ute Bank; Anke Heimburg; Heiko Julius; Doreen Breyer; Anja Thielitz; Dirk Reinhold; Michael Täger
Novel aspects of cellular action of dipeptidyl peptidase IV/CD26.
Biological chemistry 2011;392(3):153-68.
2009: Dirk Reinhold; Alexander Goihl; Sabine Wrenger; Annegret Reinhold; Ulrike C Kühlmann; Jürgen Faust; Klaus Neubert; Anja Thielitz; Stefan Brocke; Michael Täger; Siegfried Ansorge; Ute Bank
Role of dipeptidyl peptidase IV (DP IV)-like enzymes in T lymphocyte activation: investigations in DP IV/CD26-knockout mice.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2009;47(3):268-74.
2008: Anja Thielitz; Siegfried Ansorge; Ute Bank; Michael Tager; Sabine Wrenger; Harald Gollnick; Dirk Reinhold
The ectopeptidases dipeptidyl peptidase IV (DP IV) and aminopeptidase N (APN) and their related enzymes as possible targets in the treatment of skin diseases.
Frontiers in bioscience : a journal and virtual library 2008;13():2364-75.
2008: Dirk Reinhold; Ute Bank; Michael Täger; Siegfried Ansorge; Sabine Wrenger; Anja Thielitz; Uwe Lendeckel; Jürgen Faust; Klaus Neubert; Stefan Brocke
DP IV/CD26, APN/CD13 and related enzymes as regulators of T cell immunity: implications for experimental encephalomyelitis and multiple sclerosis.
Frontiers in bioscience : a journal and virtual library 2008;13():2356-63.
2007: Ute Bank; Janine Tadje; Michael Täger; Carmen Wolke; Alicja Bukowska; Annelore Ittenson; Dirk Reinhold; Martin Helmuth; Siegfried Ansorge; Ann Shakespeare; Michael Vieth; Peter Malfertheiner; Michael Naumann; Uwe Lendeckel
Inhibition of alanyl-aminopeptidase on CD4+CD25+ regulatory T-cells enhances expression of FoxP3 and TGF-beta1 and ameliorates acute colitis in mice.
International journal of molecular medicine 2007;20(4):483-92.
2007: Dirk Reinhold; Aliza Biton; Alexander Goihl; Stefanie Pieper; Uwe Lendeckel; Jürgen Faust; Klaus Neubert; Ute Bank; Michael Täger; Siegfried Ansorge; Stefan Brocke
Dual inhibition of dipeptidyl peptidase IV and aminopeptidase N suppresses inflammatory immune responses.
Annals of the New York Academy of Sciences 2007;1110():402-9.
2007: Anja Thielitz; Dirk Reinhold; Robert Vetter; Ute Bank; Martin Helmuth; Roland Hartig; Sabine Wrenger; Ingrid Wiswedel; Uwe Lendeckel; Thilo Kähne; Klaus Neubert; Jürgen Faust; Christos Zouboulis; Siegfried Ansorge; Harald Gollnick
Inhibitors of dipeptidyl peptidase IV and aminopeptidase N target major pathogenetic steps in acne initiation.
The Journal of investigative dermatology 2007;127(5):1042-51.
2006: Dirk Reinhold; Aliza Biton; Stefanie Pieper; Uwe Lendeckel; Jürgen Faust; Klaus Neubert; Ute Bank; Michael Täger; Siegfried Ansorge; Stefan Brocke
Dipeptidyl peptidase IV (DP IV, CD26) and aminopeptidase N (APN, CD13) as regulators of T cell function and targets of immunotherapy in CNS inflammation.
International immunopharmacology 2006;6(13-14):1935-42.
2006: Ute Bank; Anke Heimburg; Martin Helmuth; Sofia Stefin; Uwe Lendeckel; Dirk Reinhold; Jürgen Faust; Petra Fuchs; Bianca Sens; Klaus Neubert; Michael Täger; Siegfried Ansorge
Triggering endogenous immunosuppressive mechanisms by combined targeting of Dipeptidyl peptidase IV (DPIV/CD26) and Aminopeptidase N (APN/ CD13)--a novel approach for the treatment of inflammatory bowel disease.
International immunopharmacology 2006;6(13-14):1925-34.
2006: Carmen Wolke; Janine Tadje; Alicja Bukowska; Michael Täger; Ute Bank; Annelore Ittenson; Siegfried Ansorge; Uwe Lendeckel
Assigning the phenotype of a natural regulatory T-cell to the human T-cell line, KARPAS-299.
International journal of molecular medicine 2006;17(2):275-8.
2006: Aliza Biton; Ute Bank; Michael Täger; Siegfried Ansorge; Dirk Reinhold; Uwe Lendeckel; Stefan Brocke
Dipeptidyl peptidase IV (DP IV, CD26) and aminopeptidase N (APN, CD13) as regulators of T cell function and targets of immunotherapy in CNS inflammation.
Advances in experimental medicine and biology 2006;575():177-86.
2006: Anja Thielitz; Dirk Reinhold; Robert Vetter; Uwe Lendeckel; Thilo Kähne; Ute Bank; Martin Helmuth; Klaus Neubert; Jürgen Faust; Roland Hartig; Sabine Wrenger; Christos Zouboulis; Siegfried Ansorge; Harald Gollnick
Possible role of DP IV inhibitors in acne therapy.
Advances in experimental medicine and biology 2006;575():163-7.
2006: Ute Bank; Janine Tadje; Martin Helmuth; Sofia Stefin; Michael Täger; Carmen Wolke; Anke Wischeropp; Annelore Ittenson; Dirk Reinhold; Siegfried Ansorge; Uwe Lendeckel
Dipeptidylpeptidase IV (DPIV) and alanyl-aminopeptidases (AAPs) as a new target complex for treatment of autoimmune and inflammatory diseases-proof of concept in a mouse model of colitis.
Advances in experimental medicine and biology 2006;575():143-53.
2005: Christine E Schneemilch; Annelore Ittenson; Siegfried Ansorge; Thomas Hachenberg; Ute Bank
Effect of 2 anesthetic techniques on the postoperative proinflammatory and anti-inflammatory cytokine response and cellular immune function to minor surgery.
Journal of clinical anesthesia 2005;17(7):517-27.
2005: Christine E Schneemilch; Thomas Hachenberg; Siegfried Ansorge; Annelore Ittenson; Ute Bank
Effects of different anaesthetic agents on immune cell function in vitro.
European journal of anaesthesiology 2005;22(8):616-23.
2004: Christine E Schneemilch; Thomas Schilling; Ute Bank
Effects of general anaesthesia on inflammation.
Best practice & research. Clinical anaesthesiology 2004;18(3):493-507.
2001: Ute Bank; S Ansorge
More than destructive: neutrophil-derived serine proteases in cytokine bioactivity control.
Journal of leukocyte biology 2001;69(2):197-206.
2001: Christine E Schneemilch; Ute Bank
[Release of pro- and anti-inflammatory cytokines during different anesthesia procedures].
Anaesthesiologie und Reanimation 2001;26(1):4-10.
2000: C H Szymkowiak; E Csernok; Dirk Reinhold; Ute Bank; W L Gross; Jörn Kekow
Neutrophils synthesize and activate TGFbeta2.
Cytokine 2000;12(4):397-400.
2000: Ute Bank; B Küpper; Siegfried Ansorge
Inactivation of interleukin-6 by neutrophil proteases at sites of inflammation. Protective effects of soluble IL-6 receptor chains.
Advances in experimental medicine and biology 2000;477():431-7.
2000: Ute Bank; Sabine Krüger; J Langner; Albert Roessner
Review: peptidases and peptidase inhibitors in the pathogenesis of diseases. Disturbances in the ubiquitin-mediated proteolytic system. Protease-antiprotease imbalance in inflammatory reactions. Role of cathepsins in tumour progression.
Advances in experimental medicine and biology 2000;477():349-78.
1999: Ute Bank; B Küpper; Dirk Reinhold; T Hoffmann; Siegfried Ansorge
Evidence for a crucial role of neutrophil-derived serine proteases in the inactivation of interleukin-6 at sites of inflammation.
FEBS letters 1999;461(3):235-40.
1999: Ute Bank; Dirk Reinhold; Christine E Schneemilch; D Kunz; Hans J Synowitz; Siegfried Ansorge
Selective proteolytic cleavage of IL-2 receptor and IL-6 receptor ligand binding chains by neutrophil-derived serine proteases at foci of inflammation.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1999;19(11):1277-87.
1999: Marco Arndt; Ute Bank; Karin Frank; Bernhard A Sabel; Siegfried Ansorge; Uwe Lendeckel
R-esp1, a rat homologue of drosophila groucho, is differentially expressed after optic nerve crush and mediates NGF-induced survival of PC12 cells.
FEBS letters 1999;457(2):246-50.
1997: D Reinhold; Ute Bank; F Bühling; U Junker; Jörn Kekow; E Schleicher; S Ansorge
A detailed protocol for the measurement of TGF-beta1 in human blood samples.
Journal of immunological methods 1997;209(2):203-6.
1997: Dirk Reinhold; Ute Bank; Frank Bühling; Uwe Lendeckel; Jürgen Faust; Klaus Neubert; Siegfried Ansorge
Inhibitors of dipeptidyl peptidase IV induce secretion of transforming growth factor-beta 1 in PWM-stimulated PBMC and T cells.
Immunology 1997;91(3):354-60.
1997: Dirk Reinhold; Ute Bank; Frank Bühling; Michael Täger; Ilona Born; Jürgen Faust; Klaus Neubert; Siegfried Ansorge
Inhibitors of dipeptidyl peptidase IV (DP IV, CD26) induces secretion of transforming growth factor-beta 1 (TGF-beta 1) in stimulated mouse splenocytes and thymocytes.
Immunology letters 1997;58(1):29-35.
1997: Ute Bank; Dirk Reinhold; D Kunz; Siegfried Ansorge
Selective proteolytical cleavage of the ligand-binding chains of the IL-2-receptor and IL-6-receptor by neutrophil-derived proteases.
Advances in experimental medicine and biology 1997;421():231-42.
1997: Dirk Reinhold; Thilo Kähne; Michael Täger; Uwe Lendeckel; Frank Bühling; Ute Bank; Sabine Wrenger; Jürgen Faust; Klaus Neubert; Siegfried Ansorge
The effect of anti-CD26 antibodies on DNA synthesis and cytokine production (IL-2, IL-10 and IFN-gamma) depends on enzymatic activity of DP IV/CD26.
Advances in experimental medicine and biology 1997;421():149-55.
1996: Dirk Reinhold; Sabine Wrenger; Ute Bank; Frank Bühling; T Hoffmann; Klaus Neubert; M Kraft; R Frank; Siegfried Ansorge
CD26 mediates the action of HIV-1 Tat protein on DNA synthesis and cytokine production in U937 cells.
Immunobiology 1996;195(1):119-28.
1995: Dirk Reinhold; Ute Bank; Frank Bühling; Uwe Lendeckel; Siegfried Ansorge
Transforming growth factor beta 1 inhibits interleukin-10 mRNA expression and production in pokeweed mitogen-stimulated peripheral blood mononuclear cells and T cells.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1995;15(8):685-90.
1995: Ute Bank; Dirk Reinhold; Dagmar Kunz; Hans-Ulrich Schulz; C Schneemilch; W Brandt; Siegfried Ansorge
Effects of interleukin-6 (IL-6) and transforming growth factor-beta (TGF-beta) on neutrophil elastase release.
Inflammation 1995;19(1):83-99.
1994: Dirk Reinhold; Ute Bank; Frank Bühling; Thilo Kähne; D Kunt; Jürgen Faust; Klaus Neubert; Siegfried Ansorge
Inhibitors of dipeptidyl peptidase IV (DP IV, CD26) specifically suppress proliferation and modulate cytokine production of strongly CD26 expressing U937 cells.
Immunobiology 1994;192(1-2):121-36.
1994: Dirk Reinhold; Ute Bank; Frank Bühling; Uwe Lendeckel; Artur J Ulmer; Hans-Dieter Flad; Siegfried Ansorge
Transforming growth factor-beta 1 (TGF-beta 1) inhibits DNA synthesis of PWM-stimulated PBMC via suppression of IL-2 and IL-6 production.
Cytokine 1994;6(4):382-8.
1993: Dirk Reinhold; Ute Bank; Frank Bühling; Klaus Neubert; T Mattern; Artur J Ulmer; Hans-Dieter Flad; Siegfried Ansorge
Dipeptidyl peptidase IV (CD26) on human lymphocytes. Synthetic inhibitors of and antibodies against dipeptidyl peptidase IV suppress the proliferation of pokeweed mitogen-stimulated peripheral blood mononuclear cells, and IL-2 and IL-6 production.
Immunobiology 1993;188(4-5):403-14.
1991: Ute Bank; Dirk Reinhold; Siegfried Ansorge
[Measurement of cellular activity with the MTT test. Optimization of the method].
Allergie und Immunologie 1991;37(3-4):119-23.