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Peter Lansdorp

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Anatomy

Chemicals & Drugs

Procedures

Physiology

Living Beings

Mice

Disorders

Dyskeratosis Congenita

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Co-Publications
Name
23
Baerlocher, Gabriela
23
Dragowska, W
16
Humphries, Keith
15
Eaves, Allen
12
Hogge, Donna
10
Sutherland, Heather
9
Young, Neal
8
Rebel, Vivienne
7
Vulto, Irma
7
Schertzer, Mike
7
Brümmendorf, Tim
7
Chavez, Elizabeth
7
Krystal, Gerald
6
Martens, Uwe
6
CHANOCK, STEPHEN

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Publications

TOP 3
Breakey Vicky Rowena; Meyn Stephen; Ng Vicky; Allen Christopher; Dokal Inderjeet; Lansdorp Peter M; Abla Oussama; Dror Yigal
Hepatitis-associated aplastic anemia presenting as a familial bone marrow failure syndrome.
Hills Mark; Lansdorp Peter M
Short telomeres resulting from heritable mutations in the telomerase reverse transcriptase gene predispose for a variety of malignancies.
Lansdorp Peter M
Telomeres and disease.

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All Publications

2009: Breakey Vicky Rowena; Meyn Stephen; Ng Vicky; Allen Christopher; Dokal Inderjeet; Lansdorp Peter M; Abla Oussama; Dror Yigal
Hepatitis-associated aplastic anemia presenting as a familial bone marrow failure syndrome.
Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology 2009;31(11):884-7.
2009: Hills Mark; Lansdorp Peter M
Short telomeres resulting from heritable mutations in the telomerase reverse transcriptase gene predispose for a variety of malignancies.
Annals of the New York Academy of Sciences 2009;1176():178-90.
2009: Lansdorp Peter M
Telomeres and disease.
The EMBO journal 2009;28(17):2532-40.
2009: Decker Michelle L; Chavez Elizabeth; Vulto Irma; Lansdorp Peter M
Telomere length in Hutchinson-Gilford progeria syndrome.
Mechanisms of ageing and development 2009;130(6):377-83.
2009: Hills Mark; Lücke Kai; Chavez Elizabeth A; Eaves Connie J; Lansdorp Peter M
Probing the mitotic history and developmental stage of hematopoietic cells using single telomere length analysis (STELA).
Blood 2009;113(23):5765-75.
2009: Calado Rodrigo T; Regal Joshua A; Hills Mark; Yewdell William T; Dalmazzo Leandro F; Zago Marco A; Lansdorp Peter M; Hogge Donna; Chanock Stephen J; Estey Elihu H; Falcão Roberto P; Young Neal S
Constitutional hypomorphic telomerase mutations in patients with acute myeloid leukemia.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(4):1187-92.
2008: Halaschek-Wiener Julius; Vulto Irma; Fornika Dan; Collins Jennifer; Connors Joseph M; Le Nhu D; Lansdorp Peter M; Brooks-Wilson Angela
Reduced telomere length variation in healthy oldest old.
Mechanisms of ageing and development 2008;129(11):638-41.
2008: Alder Jonathan K; Chen Julian J-L; Lancaster Lisa; Danoff Sonye; Su Shu-chih; Cogan Joy D; Vulto Irma; Xie Mingyi; Qi Xiaodong; Tuder Rubin M; Phillips John A; Lansdorp Peter M; Loyd James E; Armanios Mary Y
Short telomeres are a risk factor for idiopathic pulmonary fibrosis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(35):13051-6.
2008: Goldman Frederick D; Aubert Geraldine; Klingelhutz Al J; Hills Mark; Cooper Sarah R; Hamilton Wendy S; Schlueter Annette J; Lambie Karen; Eaves Connie J; Lansdorp Peter M
Characterization of primitive hematopoietic cells from patients with dyskeratosis congenita.
Blood 2008;111(9):4523-31.
2008: Aubert Geraldine; Lansdorp Peter M
Telomeres and aging.
Physiological reviews 2008;88(2):557-79.
2008: Lansdorp Peter M
Telomeres, stem cells, and hematology.
Blood 2008;111(4):1759-66.
2008: Savage Sharon A; Giri Neelam; Baerlocher Gabriela M; Orr Nick; Lansdorp Peter M; Alter Blanche P
TINF2, a component of the shelterin telomere protection complex, is mutated in dyskeratosis congenita.
American journal of human genetics 2008;82(2):501-9.
2008: Berger Carolina; Jensen Michael C; Lansdorp Peter M; Gough Mike; Elliott Carole; Riddell Stanley R
Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates.
The Journal of clinical investigation 2008;118(1):294-305.
2007: Röth A; Dürig J; Himmelreich H; Bug S; Siebert R; Dührsen U; Lansdorp P M; Baerlocher G M
Short telomeres and high telomerase activity in T-cell prolymphocytic leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(12):2456-62.
2007: Baerlocher Gabriela M; Sloand Elaine M; Young Neal S; Lansdorp Peter M
Telomere length in paroxysmal nocturnal hemoglobinuria correlates with clone size.
Experimental hematology 2007;35(12):1777-81.
2007: Shepherd Bryan E; Kiem Hans-Peter; Lansdorp Peter M; Dunbar Cynthia E; Aubert Geraldine; LaRochelle Andre; Seggewiss Ruth; Guttorp Peter; Abkowitz Janis L
Hematopoietic stem-cell behavior in nonhuman primates.
Blood 2007;110(6):1806-13.
2007: Alter Blanche P; Baerlocher Gabriela M; Savage Sharon A; Chanock Stephen J; Weksler Babette B; Willner Judith P; Peters June A; Giri Neelam; Lansdorp Peter M
Very short telomere length by flow fluorescence in situ hybridization identifies patients with dyskeratosis congenita.
Blood 2007;110(5):1439-47.
2007: Calado Rodrigo T; Graf Solomon A; Wilkerson Keisha L; Kajigaya Sachiko; Ancliff Philip J; Dror Yigal; Chanock Stephen J; Lansdorp Peter M; Young Neal S
Mutations in the SBDS gene in acquired aplastic anemia.
Blood 2007;110(4):1141-6.
2007: Lansdorp Peter M
Immortal strands? Give me a break.
Cell 2007;129(7):1244-7.
2007: Westin Erik R; Chavez Elizabeth; Lee Kimberly M; Gourronc Francoise A; Riley Soraya; Lansdorp Peter M; Goldman Frederick D; Klingelhutz Aloysius J
Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts.
Aging cell 2007;6(3):383-94.
2007: Ouyang Qin; Baerlocher Gabriela; Vulto Irma; Lansdorp Peter M
Telomere length in human natural killer cell subsets.
Annals of the New York Academy of Sciences 2007;1106():240-52.
2007: Armanios Mary Y; Chen Julian J-L; Cogan Joy D; Alder Jonathan K; Ingersoll Roxann G; Markin Cheryl; Lawson William E; Xie Mingyi; Vulto Irma; Phillips John A; Lansdorp Peter M; Greider Carol W; Loyd James E
Telomerase mutations in families with idiopathic pulmonary fibrosis.
The New England journal of medicine 2007;356(13):1317-26.
2007: Sharma Sudha; Stumpo Deborah J; Balajee Adayabalam S; Bock Cheryl B; Lansdorp Peter M; Brosh Robert M; Blackshear Perry J
RECQL, a member of the RecQ family of DNA helicases, suppresses chromosomal instability.
Molecular and cellular biology 2007;27(5):1784-94.
2007: Baerlocher Gabriela M; Rice Karen; Vulto Irma; Lansdorp Peter M
Longitudinal data on telomere length in leukocytes from newborn baboons support a marked drop in stem cell turnover around 1 year of age.
Aging cell 2007;6(1):121-3.
2007: Xin Zhong-Tao; Beauchamp Adam D; Calado Rodrigo T; Bradford Jennifer W; Regal Joshua A; Shenoy Aarthi; Liang Yuying; Lansdorp Peter M; Young Neal S; Ly Hinh
Functional characterization of natural telomerase mutations found in patients with hematologic disorders.
Blood 2007;109(2):524-32.
2006: Lansdorp Peter M
Stress, social rank and leukocyte telomere length.
Aging cell 2006;5(6):583-4.
2006: Savage Sharon A; Stewart Brian J; Weksler Babette B; Baerlocher Gabriela M; Lansdorp Peter M; Chanock Stephen J; Alter Blanche P
Mutations in the reverse transcriptase component of telomerase (TERT) in patients with bone marrow failure.
Blood cells, molecules & diseases 2006;37(2):134-6.
2006: Baerlocher Gabriela M; Vulto Irma; de Jong Gary; Lansdorp Peter M
Flow cytometry and FISH to measure the average length of telomeres (flow FISH).
Nature protocols 2006;1(5):2365-76.
2006: Cheung Iris; Schertzer Michael; Rose Ann; Lansdorp Peter M
High incidence of rapid telomere loss in telomerase-deficient Caenorhabditis elegans.
Nucleic acids research 2006;34(1):96-103.
2005: Ly Hinh; Schertzer Mike; Jastaniah Wasil; Davis Jeff; Yong Siu Li; Ouyang Qin; Blackburn Elizabeth H; Parslow Tristram G; Lansdorp Peter M
Identification and functional characterization of 2 variant alleles of the telomerase RNA template gene (TERC) in a patient with dyskeratosis congenita.
Blood 2005;106(4):1246-52.
2005: Lansdorp Peter M
Major cutbacks at chromosome ends.
Trends in biochemical sciences 2005;30(7):388-95.
2005: Röth Alexander; Baerlocher Gabriela M; Schertzer Mike; Chavez Elizabeth; Dührsen Ulrich; Lansdorp Peter M
Telomere loss, senescence, and genetic instability in CD4+ T lymphocytes overexpressing hTERT.
Blood 2005;106(1):43-50.
2005: Lansdorp Peter M
Role of telomerase in hematopoietic stem cells.
Annals of the New York Academy of Sciences 2005;1044():220-7.
2005: Masutomi Kenkichi; Possemato Richard; Wong Judy M Y; Currier Jennifer L; Tothova Zuzana; Manola Judith B; Ganesan Shridar; Lansdorp Peter M; Collins Kathleen; Hahn William C
The telomerase reverse transcriptase regulates chromatin state and DNA damage responses.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(23):8222-7.
2005: Yamaguchi Hiroki; Calado Rodrigo T; Ly Hinh; Kajigaya Sachiko; Baerlocher Gabriela M; Chanock Stephen J; Lansdorp Peter M; Young Neal S
Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia.
The New England journal of medicine 2005;352(14):1413-24.
2005: Ly Hinh; Calado Rodrigo T; Allard Paulette; Baerlocher Gabriela M; Lansdorp Peter M; Young Neal S; Parslow Tristram G
Functional characterization of telomerase RNA variants found in patients with hematologic disorders.
Blood 2005;105(6):2332-9.
2004: Ochsenbein Adrian F; Riddell Stanley R; Brown Michele; Corey Lawrence; Baerlocher Gabriela M; Lansdorp Peter M; Greenberg Philip D
CD27 expression promotes long-term survival of functional effector-memory CD8+ cytotoxic T lymphocytes in HIV-infected patients.
The Journal of experimental medicine 2004;200(11):1407-17.
2004: Shepherd Bryan E; Guttorp Peter; Lansdorp Peter M; Abkowitz Janis L
Estimating human hematopoietic stem cell kinetics using granulocyte telomere lengths.
Experimental hematology 2004;32(11):1040-50.
2004: Ding Hao; Schertzer Mike; Wu Xiaoli; Gertsenstein Marina; Selig Sara; Kammori Makoto; Pourvali Reza; Poon Steven; Vulto Irma; Chavez Elizabeth; Tam Patrick P L; Nagy Andras; Lansdorp Peter M
Regulation of murine telomere length by Rtel: an essential gene encoding a helicase-like protein.
Cell 2004;117(7):873-86.
2004: Baross Agnes; Schertzer Mike; Zuyderduyn Scott D; Jones Steven J M; Marra Marco A; Lansdorp Peter M
Effect of TERT and ATM on gene expression profiles in human fibroblasts.
Genes, chromosomes & cancer 2004;39(4):298-310.
2004: Baerlocher Gabriela M; Lansdorp Peter M
Telomere length measurements using fluorescence in situ hybridization and flow cytometry.
Methods in cell biology 2004;75():719-50.
2004: Cheung Iris; Schertzer Mike; Baross Agnes; Rose Ann M; Lansdorp Peter M; Baird Duncan M
Strain-specific telomere length revealed by single telomere length analysis in Caenorhabditis elegans.
Nucleic acids research 2004;32(11):3383-91.
2003: Röth A; Vercauteren S; Sutherland H J; Lansdorp P M
Telomerase is limiting the growth of acute myeloid leukemia cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(12):2410-7.
2003: Greenwood Matthew J; Lansdorp Peter M
Telomeres, telomerase, and hematopoietic stem cell biology.
Archives of medical research 2003;34(6):489-95.
2003: Fogarty Patrick F; Yamaguchi Hiroki; Wiestner Adrian; Baerlocher Gabriela M; Sloand Elaine; Zeng Weihua S; Read Elizabeth J; Lansdorp Peter M; Young Neal S
Late presentation of dyskeratosis congenita as apparently acquired aplastic anaemia due to mutations in telomerase RNA.
Lancet 2003;362(9396):1628-30.
2003: Baerlocher Gabriela M; Lansdorp Peter M
Telomere length measurements in leukocyte subsets by automated multicolor flow-FISH.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2003;55(1):1-6.
2003: Roth Alexander; Yssel Hans; Pene Jerome; Chavez Elizabeth A; Schertzer Mike; Lansdorp Peter M; Spits Hergen; Luiten Rosalie M
Telomerase levels control the lifespan of human T lymphocytes.
Blood 2003;102(3):849-57.
2003: Yamaguchi Hiroki; Baerlocher Gabriela M; Lansdorp Peter M; Chanock Stephen J; Nunez Olga; Sloand Elaine; Young Neal S
Mutations of the human telomerase RNA gene (TERC) in aplastic anemia and myelodysplastic syndrome.
Blood 2003;102(3):916-8.
2003: Ning Yi; Xu Jing-Fan; Li Yu; Chavez Liz; Riethman Harold C; Lansdorp Peter M; Weng Nan-Ping
Telomere length and the expression of natural telomeric genes in human fibroblasts.
Human molecular genetics 2003;12(11):1329-36.
2003: Baerlocher Gabriela M; Roth Alexander; Lansdorp Peter M
Telomeres in hematopoietic stem cells.
Annals of the New York Academy of Sciences 2003;996():44-8.
2003: Brummendorf Tim H; Ersoz Inci; Hartmann Ulrike; Balabanov Stefan; Wolke Holger; Paschka Peter; Lahaye Tanja; Berner Birgit; Bartolovic Kerol; Kreil Sebastian; Berger Ute; Gschaidmeier Harald; Bokemeyer Carsten; Hehlmann Rudiger; Dietz Klaus; Lansdorp Peter M; Kanz Lothar; Hochhaus Andreas
Normalization of previously shortened telomere length under treatment with imatinib argues against a preexisting telomere length deficit in normal hematopoietic stem cells from patients with chronic myeloid leukemia.
Annals of the New York Academy of Sciences 2003;996():26-38.
2003: Baerlocher Gabriela M; Mak Jennifer; Röth Alexander; Rice Karen S; Lansdorp Peter M
Telomere shortening in leukocyte subpopulations from baboons.
Journal of leukocyte biology 2003;73(2):289-96.
2003: Tchirkov Andrei; Lansdorp Peter M
Role of oxidative stress in telomere shortening in cultured fibroblasts from normal individuals and patients with ataxia-telangiectasia.
Human molecular genetics 2003;12(3):227-32.
2003: Brümmendorf Tim H; Ersöz Inci; Hartmann Ulrike; Bartolovic Kerol; Balabanov Stefan; Wahl Alexandra; Paschka Peter; Kreil Sebastian; Lahaye Tanja; Berger Ute; Gschaidmeier Harald; Bokemeyer Carsten; Hehlmann Rüdiger; Dietz Klaus; Lansdorp Peter M; Kanz Lothar; Hochhaus Andreas
Telomere length in peripheral blood granulocytes reflects response to treatment with imatinib in patients with chronic myeloid leukemia.
Blood 2003;101(1):375-6.
2003: McBurney Michael W; Yang Xiaofeng; Jardine Karen; Hixon Mary; Boekelheide Kim; Webb John R; Lansdorp Peter M; Lemieux Madeleine
The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis.
Molecular and cellular biology 2003;23(1):38-54.
2003: Van Ziffle Jessica A G; Baerlocher Gabriela M; Lansdorp Peter M
Telomere length in subpopulations of human hematopoietic cells.
Stem cells (Dayton, Ohio) 2003;21(6):654-60.
2002: Tong Wei-Min; Cortes Ulrich; Hande M Prakash; Ohgaki Hiroko; Cavalli Luciane R; Lansdorp Peter M; Haddad Bassem R; Wang Zhao-Qi
Synergistic role of Ku80 and poly(ADP-ribose) polymerase in suppressing chromosomal aberrations and liver cancer formation.
Cancer research 2002;62(23):6990-6.
2002: Martens Uwe M; Brass Volker; Sedlacek Lucie; Pantic Milena; Exner Carolin; Guo Yalin; Engelhardt Monika; Lansdorp Peter M; Waller Cornelius F; Lange Winand
Telomere maintenance in human B lymphocytes.
British journal of haematology 2002;119(3):810-8.
2002: Brümmendorf Tim H; Mak Jennifer; Sabo Kathleen M; Baerlocher Gabriela M; Dietz Klaus; Abkowitz Janis L; Lansdorp Peter M
Longitudinal studies of telomere length in feline blood cells: implications for hematopoietic stem cell turnover in vivo.
Experimental hematology 2002;30(10):1147-52.
2002: Abramovich Carolina; Chavez Elizabeth A; Lansdorp Peter M; Humphries R Keith
Functional characterization of multiple domains involved in the subcellular localization of the hematopoietic Pbx interacting protein (HPIP).
Oncogene 2002;21(44):6766-71.
2002: Cheung Iris; Schertzer Michael; Rose Ann; Lansdorp Peter M
Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA.
Nature genetics 2002;31(4):405-9.
2002: Mousavi Parvin; Ward Rabab Kreidieh; Fels Sidney S; Sameti Mohammad; Lansdorp Peter M
Feature analysis and centromere segmentation of human chromosome images using an iterative fuzzy algorithm.
IEEE transactions on bio-medical engineering 2002;49(4):363-71.
2002: Baerlocher Gabriela M; Mak Jennifer; Tien Teri; Lansdorp Peter M
Telomere length measurement by fluorescence in situ hybridization and flow cytometry: tips and pitfalls.
Cytometry 2002;47(2):89-99.
2002: Awaya Norihiro; Baerlocher Gabriela M; Manley Thomas J; Sanders Jean E; Mielcarek Marco; Torok-Storb Beverly; Lansdorp Peter M
Telomere shortening in hematopoietic stem cell transplantation: a potential mechanism for late graft failure?
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2002;8(11):597-600.
2002: Verfaillie Catherine M; Pera Martin F; Lansdorp Peter M
Stem cells: hype and reality.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2002;():369-91.
2001: Poon S S; Lansdorp P M
Quantitative fluorescence in situ hybridization (Q-FISH).
Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] 2001;Chapter 18():Unit 18.4.
2001: Brümmendorf T H; Rufer N; Holyoake T L; Maciejewski J; Barnett M J; Eaves C J; Eaves A C; Young N; Lansdorp P M
Telomere length dynamics in normal individuals and in patients with hematopoietic stem cell-associated disorders.
Annals of the New York Academy of Sciences 2001;938():293-303; discussion 303-4.
2001: Brümmendorf T H; Rufer N; Baerlocher G M; Roosnek E; Lansdorp P M
Limited telomere shortening in hematopoietic stem cells after transplantation.
Annals of the New York Academy of Sciences 2001;938():1-7; discussion 7-8.
2001: Tong W M; Hande M P; Lansdorp P M; Wang Z Q
DNA strand break-sensing molecule poly(ADP-Ribose) polymerase cooperates with p53 in telomere function, chromosome stability, and tumor suppression.
Molecular and cellular biology 2001;21(12):4046-54.
2001: Hande M P; Balajee A S; Tchirkov A; Wynshaw-Boris A; Lansdorp P M
Extra-chromosomal telomeric DNA in cells from Atm(-/-) mice and patients with ataxia-telangiectasia.
Human molecular genetics 2001;10(5):519-28.
2001: Brümmendorf T H; Maciejewski J P; Mak J; Young N S; Lansdorp P M
Telomere length in leukocyte subpopulations of patients with aplastic anemia.
Blood 2001;97(4):895-900.
2001: Poon S S; Lansdorp P M
Measurements of telomere length on individual chromosomes by image cytometry.
Methods in cell biology 2001;64():69-96.
2000: Mathioudakis G; Storb R; McSweeney P A; Torok-Storb B; Lansdorp P M; Brümmendorf T H; Gass M J; Bryant E M; Storek J; Flowers M E; Gooley T; Nash R A
Polyclonal hematopoiesis with variable telomere shortening in human long-term allogeneic marrow graft recipients.
Blood 2000;96(12):3991-4.
2000: Martens U M; Chavez E A; Poon S S; Schmoor C; Lansdorp P M
Accumulation of short telomeres in human fibroblasts prior to replicative senescence.
Experimental cell research 2000;256(1):291-9.
1999: Poon S S; Martens U M; Ward R K; Lansdorp P M
Telomere length measurements using digital fluorescence microscopy.
Cytometry 1999;36(4):267-78.
1999: Rufer N; Brümmendorf T H; Kolvraa S; Bischoff C; Christensen K; Wadsworth L; Schulzer M; Lansdorp P M
Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood.
The Journal of experimental medicine 1999;190(2):157-67.
1999: Brümmendorf T H; Dragowska W; Lansdorp P M
Asymmetric cell divisions in hematopoietic stem cells.
Annals of the New York Academy of Sciences 1999;872():265-72; discussion 272-3.
1999: Kipling D; Wynford-Thomas D; Jones C J; Akbar A; Aspinall R; Bacchetti S; Blasco M A; Broccoli D; DePinho R A; Edwards D R; Effros R B; Harley C B; Lansdorp P M; Linskens M H; Prowse K R; Newbold R F; Olovnikov A M; Parkinson E K; Pawelec G; Pontén J; Shall S; Zijlmans M; Faragher R G
Telomere-dependent senescence.
Nature biotechnology 1999;17(4):313-4.
1999: Wan T S; Martens U M; Poon S S; Tsao S W; Chan L C; Lansdorp P M
Absence or low number of telomere repeats at junctions of dicentric chromosomes.
Genes, chromosomes & cancer 1999;24(1):83-6.
1998: Brummendorf T H; Dragowska W; Zijlmans JMJM; Thornbury G; Lansdorp P M
Asymmetric cell divisions sustain long-term hematopoiesis from single-sorted human fetal liver cells.
The Journal of experimental medicine 1998;188(6):1117-24.
1998: Rufer N; Dragowska W; Thornbury G; Roosnek E; Lansdorp P M
Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry.
Nature biotechnology 1998;16(8):743-7.
1998: Yui J; Chiu C P; Lansdorp P M
Telomerase activity in candidate stem cells from fetal liver and adult bone marrow.
Blood 1998;91(9):3255-62.
1998: Martens U M; Zijlmans J M; Poon S S; Dragowska W; Yui J; Chavez E A; Ward R K; Lansdorp P M
Short telomeres on human chromosome 17p.
Nature genetics 1998;18(1):76-80.
1997: Lansdorp P M
Self-renewal of stem cells.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 1997;3(4):171-8.
1997: Zijlmans J M; Martens U M; Poon S S; Raap A K; Tanke H J; Ward R K; Lansdorp P M
Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(14):7423-8.
1997: Cashman J D; Lapidot T; Wang J C; Doedens M; Shultz L D; Lansdorp P; Dick J E; Eaves C J
Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice.
Blood 1997;89(12):4307-16.
1997: Blair A; Hogge D E; Ailles L E; Lansdorp P M; Sutherland H J
Lack of expression of Thy-1 (CD90) on acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo.
Blood 1997;89(9):3104-12.
1997: Little M T; Langlois S; Wilson R D; Lansdorp P M
Frequency of fetal cells in sorted subpopulations of nucleated erythroid and CD34+ hematopoietic progenitor cells from maternal peripheral blood.
Blood 1997;89(7):2347-58.
1997: Miller C L; Rebel V I; Helgason C D; Lansdorp P M; Eaves C J
Impaired steel factor responsiveness differentially affects the detection and long-term maintenance of fetal liver hematopoietic stem cells in vivo.
Blood 1997;89(4):1214-23.
1997: Thorsteinsdottir U; Sauvageau G; Hough M R; Dragowska W; Lansdorp P M; Lawrence H J; Largman C; Humphries R K
Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia.
Molecular and cellular biology 1997;17(1):495-505.
1997: Lansdorp P M; Poon S; Chavez E; Dragowska V; Zijlmans M; Bryan T; Reddel R; Egholm M; Bacchetti S; Martens U
Telomeres in the haemopoietic system.
Ciba Foundation symposium 1997;211():209-18; discussion 219-22.
1997: Lansdorp P M
Intrinsic control of stem cell fate.
Stem cells (Dayton, Ohio) 1997;15 Suppl 1():223-5; discussion 225-7.
1996: Hogge D E; Lansdorp P M; Reid D; Gerhard B; Eaves C J
Enhanced detection, maintenance, and differentiation of primitive human hematopoietic cells in cultures containing murine fibroblasts engineered to produce human steel factor, interleukin-3, and granulocyte colony-stimulating factor.
Blood 1996;88(10):3765-73.
1996: Petzer A L; Eaves C J; Lansdorp P M; Ponchio L; Barnett M J; Eaves A C
Characterization of primitive subpopulations of normal and leukemic cells present in the blood of patients with newly diagnosed as well as established chronic myeloid leukemia.
Blood 1996;88(6):2162-71.
1996: Lansdorp P M; Verwoerd N P; van de Rijke F M; Dragowska V; Little M T; Dirks R W; Raap A K; Tanke H J
Heterogeneity in telomere length of human chromosomes.
Human molecular genetics 1996;5(5):685-91.
1996: Rebel V I; Miller C L; Thornbury G R; Dragowska W H; Eaves C J; Lansdorp P M
A comparison of long-term repopulating hematopoietic stem cells in fetal liver and adult bone marrow from the mouse.
Experimental hematology 1996;24(5):638-48.
1996: Rebel V I; Miller C L; Eaves C J; Lansdorp P M
The repopulation potential of fetal liver hematopoietic stem cells in mice exceeds that of their liver adult bone marrow counterparts.
Blood 1996;87(8):3500-7.
1996: Watari K; Mayani H; Lee F; Dragowska W; Lansdorp P M; Schrader J W
Production of interleukin 1beta by human hematopoietic progenitor cells.
The Journal of clinical investigation 1996;97(7):1666-74.
1996: Chiu C P; Dragowska W; Kim N W; Vaziri H; Yui J; Thomas T E; Harley C B; Lansdorp P M
Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow.
Stem cells (Dayton, Ohio) 1996;14(2):239-48.
1996: Rebel V I; Lansdorp P M
Culture of purified stem cells from fetal liver results in loss of in vivo repopulating potential.
Journal of hematotherapy 1996;5(1):25-37.
1996: Miller C L; Rebel V I; Lemieux M E; Helgason C D; Lansdorp P M; Eaves C J
Studies of W mutant mice provide evidence for alternate mechanisms capable of activating hematopoietic stem cells.
Experimental hematology 1996;24(2):185-94.
1996: Sirard C; Lapidot T; Vormoor J; Cashman J D; Doedens M; Murdoch B; Jamal N; Messner H; Addey L; Minden M; Laraya P; Keating A; Eaves A; Lansdorp P M; Eaves C J; Dick J E
Normal and leukemic SCID-repopulating cells (SRC) coexist in the bone marrow and peripheral blood from CML patients in chronic phase, whereas leukemic SRC are detected in blast crisis.
Blood 1996;87(4):1539-48.
1995: Mayani H; Lansdorp P M
Proliferation of individual hematopoietic progenitors purified from umbilical cord blood.
Experimental hematology 1995;23(14):1453-62.
1995: Rebel V I; Miller C L; Spinelli J J; Thomas T E; Eaves C J; Lansdorp P M
Nonlinear effects of radiation dose on donor-cell reconstitution by limited numbers of purified stem cells.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 1995;1(1):32-9.
1995: Ghaffari S; Dougherty G J; Lansdorp P M; Eaves A C; Eaves C J
Differentiation-associated changes in CD44 isoform expression during normal hematopoiesis and their alteration in chronic myeloid leukemia.
Blood 1995;86(8):2976-85.
1995: Lemieux M E; Rebel V I; Lansdorp P M; Eaves C J
Characterization and purification of a primitive hematopoietic cell type in adult mouse marrow capable of lymphomyeloid differentiation in long-term marrow "switch" cultures.
Blood 1995;86(4):1339-47.
1995: Sauvageau G; Thorsteinsdottir U; Eaves C J; Lawrence H J; Largman C; Lansdorp P M; Humphries R K
Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo.
Genes & development 1995;9(14):1753-65.
1995: Mayani H; Little M T; Dragowska W; Thornbury G; Lansdorp P M
Differential effects of the hematopoietic inhibitors MIP-1 alpha, TGF-beta, and TNF-alpha on cytokine-induced proliferation of subpopulations of CD34+ cells purified from cord blood and fetal liver.
Experimental hematology 1995;23(5):422-7.
1995: Lansdorp P M
Developmental changes in the function of hematopoietic stem cells.
Experimental hematology 1995;23(3):187-91.
1995: Sutherland H J; Hogge D E; Lansdorp P M; Phillips G L; Eaves A C; Eaves C J
Quantitation, mobilization, and clinical use of long-term culture-initiating cells in blood cell autografts.
Journal of hematotherapy 1995;4(1):3-10.
1994: Sauvageau G; Lansdorp P M; Eaves C J; Hogge D E; Dragowska W H; Reid D S; Largman C; Lawrence H J; Humphries R K
Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(25):12223-7.
1994: Pawliuk R; Kay R; Lansdorp P; Humphries R K
Selection of retrovirally transduced hematopoietic cells using CD24 as a marker of gene transfer.
Blood 1994;84(9):2868-77.
1994: Vaziri H; Dragowska W; Allsopp R C; Thomas T E; Harley C B; Lansdorp P M
Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(21):9857-60.
1994: Craig W; Poppema S; Little M T; Dragowska W; Lansdorp P M
CD45 isoform expression on human haemopoietic cells at different stages of development.
British journal of haematology 1994;88(1):24-30.
1994: Krystal G; Lam V; Dragowska W; Takahashi C; Appel J; Gontier A; Jenkins A; Lam H; Quon L; Lansdorp P
Transforming growth factor beta 1 is an inducer of erythroid differentiation.
The Journal of experimental medicine 1994;180(3):851-60.
1994: Watari K; Lansdorp P M; Dragowska W; Mayani H; Schrader J W
Expression of interleukin-1 beta gene in candidate human hematopoietic stem cells.
Blood 1994;84(1):36-43.
1994: Sutherland H J; Eaves C J; Lansdorp P M; Phillips G L; Hogge D E
Kinetics of committed and primitive blood progenitor mobilization after chemotherapy and growth factor treatment and their use in autotransplants.
Blood 1994;83(12):3808-14.
1994: Mayani H; Lansdorp P M
Thy-1 expression is linked to functional properties of primitive hematopoietic progenitor cells from human umbilical cord blood.
Blood 1994;83(9):2410-7.
1994: Hogge D E; Sutherland H J; Cashman J D; Lansdorp P M; Humphries R K; Eaves C J
Cytokines acting early in human haematopoiesis.
Baillière's clinical haematology 1994;7(1):49-63.
1994: Rebel V I; Dragowska W; Eaves C J; Humphries R K; Lansdorp P M
Amplification of Sca-1+ Lin- WGA+ cells in serum-free cultures containing steel factor, interleukin-6, and erythropoietin with maintenance of cells with long-term in vivo reconstituting potential.
Blood 1994;83(1):128-36.
1994: Lansdorp P M; Dragowska W; Thomas T E; Little M T; Mayani H
Age-related decline in proliferative potential of purified stem cell candidates.
Blood cells 1994;20(2-3):376-80; discussion 380-1.
1994: Thomas T E; Lansdorp P M
Selective separation of cells using magnetic colloids.
Progress in clinical and biological research 1994;389():65-77.
1994: Roath S; Thomas T E; Watson J H; Lansdorp P M; Smith R J; Richards A J
Specific capture of targeted hematopoietic cells by high gradient magnetic separation by the use of ordered wire array filters and tetrameric antibody complexes linked to a dextran iron particle.
Progress in clinical and biological research 1994;389():155-63.
1993: Mayani H; Dragowska W; Lansdorp P M
Lineage commitment in human hemopoiesis involves asymmetric cell division of multipotent progenitors and does not appear to be influenced by cytokines.
Journal of cellular physiology 1993;157(3):579-86.
1993: Mayani H; Dragowska W; Lansdorp P M
Characterization of functionally distinct subpopulations of CD34+ cord blood cells in serum-free long-term cultures supplemented with hematopoietic cytokines.
Blood 1993;82(9):2664-72.
1993: Hogge D E; Sutherland H J; Lansdorp P M; Phillips G L; Eaves C J
The elusive peripheral blood hemopoietic stem cell.
Seminars in hematology 1993;30(4 Suppl 4):82-9; discussion 90-1.
1993: Lansdorp P M; Dragowska W
Maintenance of hematopoiesis in serum-free bone marrow cultures involves sequential recruitment of quiescent progenitors.
Experimental hematology 1993;21(10):1321-7.
1993: Lansdorp P M; Dragowska W; Mayani H
Ontogeny-related changes in proliferative potential of human hematopoietic cells.
The Journal of experimental medicine 1993;178(3):787-91.
1993: Mayani H; Dragowska W; Lansdorp P M
Cytokine-induced selective expansion and maturation of erythroid versus myeloid progenitors from purified cord blood precursor cells.
Blood 1993;81(12):3252-8.
1993: Craig W; Kay R; Cutler R L; Lansdorp P M
Expression of Thy-1 on human hematopoietic progenitor cells.
The Journal of experimental medicine 1993;177(5):1331-42.
1993: Thomas T E; Richards A J; Roath O S; Watson J H; Smith R J; Lansdorp P M
Positive selection of human blood cells using improved high gradient magnetic separation filters.
Journal of hematotherapy 1993;2(3):297-303.
1992: Udomsakdi C; Eaves C J; Lansdorp P M; Eaves A C
Phenotypic heterogeneity of primitive leukemic hematopoietic cells in patients with chronic myeloid leukemia.
Blood 1992;80(10):2522-30.
1992: Udomsakdi C; Lansdorp P M; Hogge D E; Reid D S; Eaves A C; Eaves C J
Characterization of primitive hematopoietic cells in normal human peripheral blood.
Blood 1992;80(10):2513-21.
1992: Thomas T E; Abraham S J; Otter A J; Blackmore E W; Lansdorp P M
High gradient magnetic separation of cells on the basis of expression levels of cell surface antigens.
Journal of immunological methods 1992;154(2):245-52.
1992: Hughes P F; Thacker J D; Hogge D; Sutherland H J; Thomas T E; Lansdorp P M; Eaves C J; Humphries R K
Retroviral gene transfer to primitive normal and leukemic hematopoietic cells using clinically applicable procedures.
The Journal of clinical investigation 1992;89(6):1817-24.
1992: Lansdorp P M; Dragowska W
Long-term erythropoiesis from constant numbers of CD34+ cells in serum-free cultures initiated with highly purified progenitor cells from human bone marrow.
The Journal of experimental medicine 1992;175(6):1501-9.
1992: Thomas T E; Abraham S J; Phillips G L; Lansdorp P M
A simple procedure for large-scale density separation of bone marrow cells for transplantation.
Transplantation 1992;53(5):1163-5.
1992: Wognum A W; Krystal G; Eaves C J; Eaves A C; Lansdorp P M
Increased erythropoietin-receptor expression on CD34-positive bone marrow cells from patients with chronic myeloid leukemia.
Blood 1992;79(3):642-9.
1992: Eaves C; Fraser C; Udomsakdi C; Sutherland H; Barnett M; Szilvassy S; Hogge D; Lansdorp P; Eaves A
Manipulation of the hematopoietic stem cell in vitro.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1992;6 Suppl 1():27-30.
1992: Eaves C J; Sutherland H J; Udomsakdi C; Lansdorp P M; Szilvassy S J; Fraser C C; Humphries R K; Barnett M J; Phillips G L; Eaves A C
The human hematopoietic stem cell in vitro and in vivo.
Blood cells 1992;18(2):301-7.
1992: Craig W H; Thomas T E; Lansdorp P M
Use of lectins for characterization and purification of human bone marrow cells that express CD34.
Journal of hematotherapy 1992;1(1):55-64.
1992: Thomas T E; Lansdorp P M
Purification of CD34 positive cells from human bone marrow using high gradient magnetic separation.
Progress in clinical and biological research 1992;377():537-44.
1992: Lansdorp P M; Schmitt C; Sutherland H J; Craig W H; Dragowska W; Thomas T E; Eaves C J
Hemopoietic stem cell characterization.
Progress in clinical and biological research 1992;377():475-84; discussion 485-6.
1991: Sutherland H J; Eaves C J; Lansdorp P M; Thacker J D; Hogge D E
Differential regulation of primitive human hematopoietic cells in long-term cultures maintained on genetically engineered murine stromal cells.
Blood 1991;78(3):666-72.
1991: Eaves C J; Cashman J D; Kay R J; Dougherty G J; Otsuka T; Gaboury L A; Hogge D E; Lansdorp P M; Eaves A C; Humphries R K
Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. II. Analysis of positive and negative regulators produced by stromal cells within the adherent layer.
Blood 1991;78(1):110-7.
1991: Udomsakdi C; Eaves C J; Sutherland H J; Lansdorp P M
Separation of functionally distinct subpopulations of primitive human hematopoietic cells using rhodamine-123.
Experimental hematology 1991;19(5):338-42.
1991: Eaves C J; Sutherland H J; Cashman J D; Otsuka T; Lansdorp P M; Humphries R K; Eaves A C; Hogge D E
Regulation of primitive human hematopoietic cells in long-term marrow culture.
Seminars in hematology 1991;28(2):126-31.
1991: Terstappen L W; Huang S; Safford M; Lansdorp P M; Loken M R
Sequential generations of hematopoietic colonies derived from single nonlineage-committed CD34+CD38- progenitor cells.
Blood 1991;77(6):1218-27.
1991: Lansdorp P M; Smith C; Safford M; Terstappen L W; Thomas T E
Single laser three color immunofluorescence staining procedures based on energy transfer between phycoerythrin and cyanine 5.
Cytometry 1991;12(8):723-30.
1990: Szilvassy S J; Humphries R K; Lansdorp P M; Eaves A C; Eaves C J
Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategy.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(22):8736-40.
1990: Wognum A W; Lansdorp P M; Humphries R K; Krystal G
Detection and isolation of the erythropoietin receptor using biotinylated erythropoietin.
Blood 1990;76(4):697-705.
1990: Wognum A W; Lansdorp P M; Krystal G
Immunochemical analysis of monoclonal antibodies to human erythropoietin.
Experimental hematology 1990;18(3):228-33.
1989: Szilvassy S J; Fraser C C; Eaves C J; Lansdorp P M; Eaves A C; Humphries R K
Retrovirus-mediated gene transfer to purified hemopoietic stem cells with long-term lympho-myelopoietic repopulating ability.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(22):8798-802.
1989: Sutherland H J; Eaves C J; Eaves A C; Dragowska W; Lansdorp P M
Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro.
Blood 1989;74(5):1563-70.
1989: Szilvassy S J; Lansdorp P M; Humphries R K; Eaves A C; Eaves C J
Isolation in a single step of a highly enriched murine hematopoietic stem cell population with competitive long-term repopulating ability.
Blood 1989;74(3):930-9.
1989: Wognum A W; Lansdorp P M; Eaves A C; Krystal G
An enzyme-linked immunosorbent assay for erythropoietin using monoclonal antibodies, tetrameric immune complexes, and substrate amplification.
Blood 1989;74(2):622-8.
1989: Thomas T E; Sutherland H J; Lansdorp P M
Specific binding and release of cells from beads using cleavable tetrameric antibody complexes.
Journal of immunological methods 1989;120(2):221-31.
1988: Humphries R K; Abraham S; Krystal G; Lansdorp P; Lemoine F; Eaves C J
Activation of multiple hemopoietic growth factor genes in Abelson virus-transformed myeloid cells.
Experimental hematology 1988;16(9):774-81.
1988: Thomas T E; Lansdorp P M
Immunoadsorption of T cells onto glass beads using tetramolecular complexes of monoclonal antibodies.
Journal of immunological methods 1988;112(2):219-26.
1988: Wognum A W; Lansdorp P M; Eaves C J; Krystal G
Use of a sensitive bioimmunoabsorbent assay to isolate and characterize monoclonal antibodies to biologically active human erythropoietin.
Blood 1988;71(6):1731-7.

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